Gene: ITGA3 (integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor))  Homo sapiens

Symbol: ITGA3
Name: integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Description: The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antigen identified by monoclonal antibody J143; CD49 antigen-like family member C; CD49C; FLJ34631; FLJ34704; FRP-2; galactoprotein B3; GAP-B3; GAPB3; ILNEB; integrin alpha-3; MSK18; OTTHUMP00000220803; VCA-2; very late activation protein 3 receptor, alpha-3 subunit; VL3A; VLA-3 subunit alpha; VLA3a
Orthologs: Mus musculus : Itga3 (integrin alpha 3)  MGI
Rattus norvegicus : Itga3 (integrin, alpha 3)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11749,146,618 - 49,181,898+NCBI
Human Genome Assembly HuRef1743,500,496 - 43,535,731+NCBI
Human Genome Assembly GRCh371748,133,340 - 48,167,849+NCBI
Human Genome Assembly Build 361745,488,730 - 45,522,843+NCBI
Human Cytogenetic Map17q21.33 NCBI
Human Genome Assembly1745,488,729 - 45,522,843 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on ITGA3
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1321177
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-04-16
Status: ACTIVE