MMP1 (matrix metallopeptidase 1 (interstitial collagenase))

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Keyword

Gene: MMP1 (matrix metallopeptidase 1 (interstitial collagenase)) Homo sapiens

Symbol:

MMP1

Name:

matrix metallopeptidase 1 (interstitial collagenase)

Description:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

CLG; CLGN; fibroblast collagenase; interstitial collagenase; matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1 (interstitial collagenase); OTTHUMP00000045866

Orthologs:

Rattus norvegicus : Mmp1 (matrix metallopeptidase 1 (interstitial collagenase))

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	11	102,530,130 - 102,538,456	-	NCBI
Human Genome Assembly HuRef	11	98,588,616 - 98,596,940	-	NCBI
Human Genome Assembly GRCh37	11	102,660,641 - 102,668,966	-	NCBI
Human Genome Assembly Build 36	11	102,165,861 - 102,174,104	-	NCBI
Human Cytogenetic Map	11	q22.3		NCBI
Human Genome Assembly	11	102,165,860 - 102,174,104		NCBI