Gene: CHEK1 (checkpoint kinase 1)  Homo sapiens Symbol: CHEK1 Name: checkpoint kinase 1 Description: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011] Type: protein-coding RefSeq Status: REVIEWED Also known as: cell cycle checkpoint kinase; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHK1; CHK1 checkpoint homolog; Chk1-S; OTTHUMP00000231300; OTTHUMP00000231301; OTTHUMP00000231306; OTTHUMP00000231307; OTTHUMP00000231309; serine/threonine-protein kinase Chk1 Orthologs: Mus musculus : Chek1 (checkpoint kinase 1)  MGI Rattus norvegicus : Chek1 (checkpoint kinase 1) Latest Assembly: Human Genome Assembly GRCh37 Position: Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI Human Genome Assembly Build 36 11 125,001,547 - 125,030,847 + NCBI Human Cytogenetic Map 11 q24.2   NCBI Human Genome Assembly 11 125,001,546 - 125,030,847   NCBI Model Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19) Annotation    (Toggle Detail/Summary View) Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Neoplasm Metastasis   IEP   2317235 associated with Pancreatic Neoplasms RGD   Pancreatic Neoplasms Disease_progression IAGP   2317234 DNA:SNP: :35G>A (human) RGD   Gene-Chemical Interaction Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) 1,3-dinitrobenzene increases expression ISO RGD:620545 6480464 3-dinitrobenzene results in increased expression of CHEK1 mRNA CTD PMID:22841810 17alpha-ethynylestradiol affects expression ISO RGD:732293 6480464 Ethinyl Estradiol affects the expression of CHEK1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:732293 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHEK1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:732293 6480464 Ethinyl Estradiol results in increased expression of CHEK1 mRNA CTD PMID:17942748 17beta-estradiol increases expression EXP   6480464 Estradiol results in increased expression of CHEK1 mRNA CTD PMID:16474171 17beta-estradiol increases expression EXP   6480464 Estradiol results in increased expression of CHEK1 mRNA CTD PMID:16474171 PMID:19167446 17beta-estradiol affects expression ISO RGD:732293 6480464 Estradiol affects the expression of CHEK1 mRNA CTD PMID:15598610 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression EXP   6480464 Metribolone results in increased expression of CHEK1 mRNA CTD PMID:19318562 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases phosphorylation EXP   6480464 Metribolone results in increased phosphorylation of CHEK1 protein CTD PMID:23272087 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732293 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHEK1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732293 6480464 Tetrachlorodibenzodioxin affects the expression of CHEK1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP   6480464 Tetrachlorodibenzodioxin results in decreased expression of CHEK1 mRNA CTD PMID:21802500 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:732293 6480464 Tetrachlorodibenzodioxin results in increased expression of CHEK1 mRNA CTD PMID:15667827 PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:732293 6480464 Tetrachlorodibenzodioxin results in increased expression of CHEK1 mRNA CTD PMID:19465110 PMID:15667827 2,6-di-tert-butyl-4-methylphenol increases expression ISO RGD:732293 6480464 Butylated Hydroxytoluene results in increased expression of CHEK1 mRNA CTD PMID:19000923 2-methylcholine affects expression EXP   6480464 beta-methylcholine affects the expression of CHEK1 mRNA CTD PMID:21179406 3,3',5-triiodo-L-thyronine increases phosphorylation EXP   6480464 Triiodothyronine analog results in increased phosphorylation of CHEK1 protein CTD PMID:22383522 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:732293 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of CHEK1 mRNA CTD PMID:20188158 4-hydroxynon-2-enal decreases expression ISO RGD:732293 6480464 4-hydroxy-2-nonenal results in decreased expression of CHEK1 mRNA CTD PMID:19191707 5-aza-2'-deoxycytidine affects localization EXP   6480464 decitabine affects the localization of CHEK1 protein modified form CTD PMID:17991895 5-fluoro-2'-deoxyuridine multiple interactions EXP   6480464 Floxuridine results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21613406 PMID:22194930 5-fluorouracil affects response to substance EXP   6480464 CHEK1 protein affects the susceptibility to Fluorouracil CTD PMID:18698031 5-fluorouracil decreases expression ISO RGD:732293 6480464 Fluorouracil results in decreased expression of CHEK1 mRNA CTD PMID:19272435 5-fluorouracil multiple interactions EXP   6480464 Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21613406 PMID:22194930 5-fluorouracil multiple interactions EXP   6480464 TP53 protein inhibits the reaction [Fluorouracil results in increased expression of CHEK1 protein]; more ... CTD PMID:15016801 5-fluorouracil increases expression EXP   6480464 Fluorouracil results in increased expression of CHEK1 protein CTD PMID:15016801 5-fluorouracil multiple interactions EXP   6480464 [CHEK1 protein co-treated with TP53 protein] affects the susceptibility to Fluorouracil; more ... CTD PMID:18698031 7,12-dimethyltetraphene increases expression ISO RGD:732293 6480464 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CHEK1 protein CTD PMID:20025956 acrylamide increases expression ISO RGD:732293 6480464 Acrylamide results in increased expression of CHEK1 protein CTD PMID:20025956 aflatoxin B1 affects expression EXP   6480464 Aflatoxin B1 affects the expression of CHEK1 protein CTD PMID:20106945 all-trans-retinoic acid decreases expression EXP   6480464 Tretinoin results in decreased expression of CHEK1 mRNA CTD PMID:21934132 all-trans-retinoic acid increases expression ISO RGD:732293 6480464 Tretinoin results in increased expression of CHEK1 protein CTD PMID:20025956 ammonium chloride affects expression ISO RGD:620545 6480464 Ammonium Chloride affects the expression of CHEK1 mRNA CTD PMID:16483693 ammonium chloride decreases expression ISO RGD:620545 6480464 Ammonium Chloride results in decreased expression of CHEK1 protein CTD PMID:16483693 anthracene-1,8,9-triol increases expression ISO RGD:732293 6480464 Anthralin results in increased expression of CHEK1 protein CTD PMID:20025956 aphidicolin multiple interactions ISO RGD:732293 6480464 [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein]; more ... CTD PMID:22003191 benzo[a]pyrene increases phosphorylation EXP   6480464 Benzo(a)pyrene results in increased phosphorylation of CHEK1 protein CTD PMID:20542099 benzo[a]pyrene multiple interactions EXP   6480464 cobaltous chloride promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of CHEK1 protein] CTD PMID:20228066 benzo[a]pyrene multiple interactions EXP   6480464 CLSPN mRNA affects the reaction [Benzo(a)pyrene results in increased phosphorylation of CHEK1 protein] CTD PMID:19464357 benzo[a]pyrene decreases expression EXP   6480464 Benzo(a)pyrene results in decreased expression of CHEK1 mRNA CTD PMID:21802500 benzo[a]pyrene increases phosphorylation EXP   6480464 Benzo(a)pyrene results in increased phosphorylation of CHEK1 protein CTD PMID:19464357 more ... benzo[a]pyrene increases expression ISO RGD:620545 6480464 Benzo(a)pyrene results in increased expression of CHEK1 protein modified form CTD PMID:21604763 bis(2-chloroethyl) sulfide multiple interactions EXP   6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK1 protein]; more ... CTD PMID:22119920 bis(2-chloroethyl) sulfide increases phosphorylation EXP   6480464 Mustard Gas results in increased phosphorylation of CHEK1 protein CTD PMID:22119920 bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of CHEK1 mRNA CTD PMID:16474171 busulfan multiple interactions EXP   6480464 [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased phosphorylation of CHEK1 protein CTD PMID:20933509 caffeine multiple interactions EXP   6480464 Caffeine inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein] CTD PMID:19261750 caffeine multiple interactions EXP   6480464 Caffeine inhibits the reaction [resveratrol results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]]; more ... CTD PMID:15975956 caffeine decreases expression ISO RGD:732293 6480464 Caffeine results in decreased expression of CHEK1 protein modified form CTD PMID:21505179 caffeine decreases phosphorylation EXP   6480464 Caffeine results in decreased phosphorylation of CHEK1 protein CTD PMID:21561856 caffeine multiple interactions EXP   6480464 Caffeine inhibits the reaction [Hydroxyurea promotes the reaction [ATR protein results in increased phosphorylation of and results in increased activity of CHEK1 protein]] CTD PMID:18158334 carmustine multiple interactions EXP   6480464 ATR protein affects the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; more ... CTD PMID:19261750 catechol increases expression ISO RGD:732293 6480464 catechol results in increased expression of CHEK1 protein CTD PMID:20025956 cefaloridine increases expression ISO RGD:620545 6480464 Cephaloridine results in increased expression of CHEK1 mRNA CTD PMID:18500788 chlorpyrifos decreases expression ISO RGD:732293 6480464 Chlorpyrifos results in decreased expression of CHEK1 mRNA CTD PMID:20350560 cholic acid increases expression ISO RGD:732293 6480464 Cholic Acid results in increased expression of CHEK1 protein CTD PMID:20025956 choline affects expression EXP   6480464 Choline affects the expression of CHEK1 mRNA CTD PMID:17616785 choline multiple interactions ISO RGD:732293 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHEK1 mRNA CTD PMID:20938992 ciprofloxacin increases expression ISO RGD:620545 6480464 Ciprofloxacin results in increased expression of CHEK1 protein CTD PMID:18512786 cisplatin multiple interactions EXP   6480464 BRCA1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased activity of and results in increased phosphorylation of CHEK1 protein]]]; more ... CTD PMID:21875941 cisplatin multiple interactions ISO RGD:732293 6480464 [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Cisplatin results in increased expression of CHEK2 mRNA]; more ... CTD PMID:22003191 cisplatin multiple interactions EXP   6480464 ESR2 protein inhibits the reaction [Cisplatin results in increased phosphorylation of CHEK1 protein] CTD PMID:20623183 cisplatin increases phosphorylation EXP   6480464 Cisplatin results in increased phosphorylation of CHEK1 protein CTD PMID:20623183 more ... cisplatin multiple interactions EXP   6480464 Cisplatin results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21107699 PMID:21875941 cisplatin increases phosphorylation ISO RGD:732293 6480464 Cisplatin results in increased phosphorylation of CHEK1 protein CTD PMID:21285353 PMID:22006019 cisplatin increases activity EXP   6480464 Cisplatin results in increased activity of CHEK1 protein CTD PMID:21592546 PMID:21324906 cisplatin increases phosphorylation EXP   6480464 Cisplatin results in increased phosphorylation of CHEK1 protein CTD PMID:21285353 PMID:21356574 cisplatin increases phosphorylation ISO RGD:732293 6480464 Cisplatin results in increased phosphorylation of CHEK1 protein CTD PMID:22006019 PMID:21285353 cisplatin multiple interactions ISO RGD:732293 6480464 PRKDC protein mutant form promotes the reaction [Cisplatin results in increased phosphorylation of CHEK1 protein] CTD PMID:21324906 cisplatin multiple interactions EXP   6480464 ERCC6 protein inhibits the reaction [Cisplatin results in increased activity of CHEK1 protein] CTD PMID:21324906 cisplatin multiple interactions EXP   6480464 Lovastatin inhibits the reaction [Cisplatin results in increased phosphorylation of CHEK1 protein] CTD PMID:21356574 cisplatin increases phosphorylation EXP   6480464 Cisplatin results in increased phosphorylation of CHEK1 protein CTD PMID:21356574 PMID:21285353 cisplatin increases activity EXP   6480464 Cisplatin results in increased activity of CHEK1 protein CTD PMID:21324906 PMID:21592546 cisplatin decreases expression EXP   6480464 Cisplatin results in decreased expression of CHEK1 protein CTD PMID:12740909 clofarabine multiple interactions EXP   6480464 [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased phosphorylation of CHEK1 protein CTD PMID:20933509 clofibrate increases expression ISO RGD:732293 6480464 Clofibrate results in increased expression of CHEK1 protein CTD PMID:20025956 cobalt dichloride decreases expression EXP   6480464 cobaltous chloride results in decreased expression of CHEK1 mRNA CTD PMID:19376846 PMID:19320972 cobalt dichloride decreases expression EXP   6480464 cobaltous chloride results in decreased expression of CHEK1 mRNA CTD PMID:19320972 PMID:19376846 cobalt dichloride increases phosphorylation EXP   6480464 cobaltous chloride results in increased phosphorylation of CHEK1 protein CTD PMID:20228066 cobalt dichloride multiple interactions EXP   6480464 cobaltous chloride promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of CHEK1 protein] CTD PMID:20228066 copper atom increases expression ISO RGD:620545 6480464 Copper results in increased expression of CHEK1 mRNA CTD PMID:22465980 copper atom multiple interactions EXP   6480464 [NSC 689534 binds to Copper] which results in decreased expression of CHEK1 mRNA CTD PMID:20971185 copper(0) increases expression ISO RGD:620545 6480464 Copper results in increased expression of CHEK1 mRNA CTD PMID:22465980 copper(0) multiple interactions EXP   6480464 [NSC 689534 binds to Copper] which results in decreased expression of CHEK1 mRNA CTD PMID:20971185 copper(2+) sulfate decreases expression EXP   6480464 Copper Sulfate results in decreased expression of CHEK1 mRNA CTD PMID:19549813 coumestrol multiple interactions EXP   6480464 [Coumestrol co-treated with resveratrol] results in increased expression of CHEK1 mRNA; more ... CTD PMID:19167446 coumestrol increases expression EXP   6480464 Coumestrol results in increased expression of CHEK1 mRNA CTD PMID:19167446 curcumin decreases response to substance EXP   6480464 CHEK1 protein results in decreased susceptibility to Curcumin CTD PMID:18602917 curcumin increases activity EXP   6480464 Curcumin results in increased activity of CHEK1 protein CTD PMID:18602917 curcumin increases phosphorylation EXP   6480464 Curcumin results in increased phosphorylation of CHEK1 protein CTD PMID:19401701 cyclosporin A decreases expression EXP   6480464 Cyclosporine results in decreased expression of CHEK1 mRNA CTD PMID:20106945 cyclosporin A decreases expression EXP   6480464 Cyclosporine results in decreased expression of CHEK1 mRNA CTD PMID:20106945 PMID:21632981 diarsenic trioxide increases phosphorylation ISO RGD:732293 6480464 arsenic trioxide results in increased phosphorylation of CHEK1 protein CTD PMID:16891316 diarsenic trioxide increases phosphorylation EXP   6480464 arsenic trioxide results in increased phosphorylation of CHEK1 protein CTD PMID:16891316 dibutyl phthalate decreases expression ISO RGD:732293 6480464 Dibutyl Phthalate results in decreased expression of CHEK1 mRNA CTD PMID:21266533 digitoxin decreases expression EXP   6480464 Digitoxin results in decreased expression of CHEK1 protein; more ... CTD PMID:22037315 doxorubicin multiple interactions EXP   6480464 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Doxorubicin results in increased phosphorylation of CHEK1 protein]; more ... CTD PMID:17085670 doxorubicin increases phosphorylation EXP   6480464 Doxorubicin results in increased phosphorylation of CHEK1 protein CTD PMID:17085670 more ... doxorubicin increases phosphorylation EXP   6480464 Doxorubicin results in increased phosphorylation of CHEK1 protein CTD PMID:17088865 more ... doxorubicin multiple interactions EXP   6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased phosphorylation of CHEK1 protein] CTD PMID:21356574 PMID:17088865 doxorubicin increases phosphorylation EXP   6480464 Doxorubicin results in increased phosphorylation of CHEK1 protein CTD PMID:21356574 more ... doxorubicin increases phosphorylation EXP   6480464 Doxorubicin results in increased phosphorylation of CHEK1 protein CTD PMID:21356574 more ... doxorubicin increases phosphorylation EXP   6480464 Doxorubicin results in increased phosphorylation of CHEK1 protein CTD PMID:17088865 more ... doxorubicin affects response to substance EXP   6480464 CHEK1 protein affects the susceptibility to Doxorubicin CTD PMID:16217747 PMID:18698031 doxorubicin multiple interactions EXP   6480464 TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Doxorubicin] CTD PMID:18698031 doxorubicin increases phosphorylation EXP   6480464 Doxorubicin results in increased phosphorylation of CHEK1 protein CTD PMID:17085670 more ... doxorubicin multiple interactions EXP   6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased phosphorylation of CHEK1 protein] CTD PMID:17088865 PMID:21356574 doxorubicin multiple interactions EXP   6480464 Doxorubicin results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:17320279 doxorubicin decreases expression EXP   6480464 Doxorubicin results in decreased expression of CHEK1 protein CTD PMID:15870702 doxorubicin decreases expression EXP   6480464 Doxorubicin results in decreased expression of CHEK1 mRNA CTD PMID:16036217 doxorubicin multiple interactions EXP   6480464 Doxorubicin promotes the reaction [DNMT1 protein binds to CHEK1 protein] CTD PMID:17991895 doxorubicin affects response to substance EXP   6480464 CHEK1 protein affects the susceptibility to Doxorubicin CTD PMID:18698031 PMID:16217747 doxorubicin multiple interactions EXP   6480464 Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]] CTD PMID:15489221 etoposide affects response to substance EXP   6480464 CHEK1 protein affects the susceptibility to Etoposide CTD PMID:18698031 etoposide multiple interactions EXP   6480464 TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide] CTD PMID:18698031 fenofibrate increases expression ISO RGD:620545 6480464 Fenofibrate results in increased expression of CHEK1 mRNA CTD PMID:17264098 folic acid affects expression EXP   6480464 Folic Acid affects the expression of CHEK1 mRNA CTD PMID:16361273 folic acid multiple interactions ISO RGD:732293 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHEK1 mRNA CTD PMID:20938992 furan increases expression ISO RGD:620545 6480464 furan results in increased expression of CHEK1 mRNA CTD PMID:20562052 furan increases expression ISO RGD:732293 6480464 furan results in increased expression of CHEK1 mRNA CTD PMID:20194422 furan increases expression ISO RGD:620545 6480464 furan results in increased expression of CHEK1 mRNA CTD PMID:20562052 PMID:22079235 furosemide affects expression ISO RGD:620545 6480464 Furosemide affects the expression of CHEK1 mRNA CTD PMID:17497460 genistein increases expression EXP   6480464 Genistein results in increased expression of CHEK1 mRNA CTD PMID:16474171 Goe 6976 decreases activity EXP   6480464 Go 6976 results in decreased activity of CHEK1 protein CTD PMID:20619533 hydrogen peroxide decreases expression EXP   6480464 Hydrogen Peroxide results in decreased expression of CHEK1 mRNA CTD PMID:12414654 hydroxyurea multiple interactions EXP   6480464 Caffeine inhibits the reaction [Hydroxyurea promotes the reaction [ATR protein results in increased phosphorylation of and results in increased activity of CHEK1 protein]] CTD PMID:18158334 hydroxyurea decreases expression ISO RGD:732293 6480464 Hydroxyurea results in decreased expression of CHEK1 mRNA CTD PMID:12929121 indole-3-methanol affects expression ISO RGD:620545 6480464 indole-3-carbinol affects the expression of CHEK1 mRNA CTD PMID:21396975 indole-3-methanol multiple interactions ISO RGD:620545 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHEK1 mRNA CTD PMID:22129741 iron dichloride increases expression ISO RGD:732293 6480464 ferrous chloride results in increased expression of CHEK1 protein CTD PMID:20025956 iron trichloride increases expression ISO RGD:732293 6480464 ferric chloride results in increased expression of CHEK1 protein CTD PMID:20025956 isoflurane decreases expression ISO RGD:620545 6480464 Isoflurane results in decreased expression of CHEK1 mRNA CTD PMID:16978161 L-methionine multiple interactions ISO RGD:732293 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHEK1 mRNA CTD PMID:20938992 lead diacetate increases expression ISO RGD:732293 6480464 lead acetate results in increased expression of CHEK1 mRNA CTD PMID:22609695 leptomycin B decreases expression EXP   6480464 leptomycin B results in decreased expression of CHEK1 mRNA CTD PMID:20803015 lovastatin multiple interactions EXP   6480464 Lovastatin inhibits the reaction [Cisplatin results in increased phosphorylation of CHEK1 protein] CTD PMID:21356574 lovastatin multiple interactions EXP   6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased phosphorylation of CHEK1 protein] CTD PMID:17088865 PMID:21356574 lovastatin multiple interactions EXP   6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased phosphorylation of CHEK1 protein] CTD PMID:21356574 PMID:17088865 menadione decreases expression EXP   6480464 Vitamin K 3 results in decreased expression of CHEK1 mRNA CTD PMID:12414654 methyl isocyanate increases expression ISO RGD:732293 6480464 methyl isocyanate results in increased expression of CHEK1 mRNA CTD PMID:22223508 methylmercury chloride decreases expression ISO RGD:732293 6480464 methylmercuric chloride results in decreased expression of CHEK1 mRNA CTD PMID:20061341 N-acetyl-L-cysteine multiple interactions EXP   6480464 Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]] CTD PMID:15489221 N-nitrosodiethylamine multiple interactions ISO RGD:732293 6480464 ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 protein]; more ... CTD PMID:19919837 N-nitrosodiethylamine multiple interactions ISO RGD:620545 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHEK1 mRNA CTD PMID:22129741 N-nitrosodiethylamine increases expression ISO RGD:732293 6480464 Diethylnitrosamine results in increased expression of CHEK1 mRNA CTD PMID:17854601 PMID:19919837 N-nitrosodiethylamine increases expression ISO RGD:732293 6480464 Diethylnitrosamine results in increased expression of CHEK1 protein CTD PMID:19919837 N-nitrosodiethylamine multiple interactions ISO RGD:732293 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 mRNA] CTD PMID:17854601 N-nitrosodiethylamine increases expression ISO RGD:732293 6480464 Diethylnitrosamine results in increased expression of CHEK1 mRNA CTD PMID:19919837 PMID:17854601 ochratoxin A increases expression ISO RGD:620545 6480464 ochratoxin A results in increased expression of CHEK1 mRNA CTD PMID:19237604 ozone increases expression ISO RGD:732293 6480464 Ozone results in increased expression of CHEK1 mRNA CTD PMID:19555225 paclitaxel decreases expression ISO RGD:732293 6480464 Paclitaxel results in decreased expression of CHEK1 mRNA CTD PMID:12929121 paracetamol increases expression ISO RGD:732293 6480464 Acetaminophen results in increased expression of CHEK1 protein CTD PMID:20025956 phorbol 13-acetate 12-myristate increases expression ISO RGD:732293 6480464 Tetradecanoylphorbol Acetate results in increased expression of CHEK1 mRNA CTD PMID:19000923 pirinixic acid increases expression ISO RGD:732293 6480464 pirinixic acid results in increased expression of CHEK1 mRNA CTD PMID:20813756 pirinixic acid multiple interactions ISO RGD:732293 6480464 [pirinixic acid co-treated with PPARA] results in increased expression of CHEK1 mRNA CTD PMID:20813756 platinum multiple interactions EXP   6480464 Platinum analog results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21107699 platinum(0) multiple interactions EXP   6480464 Platinum analog results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21107699 propiconazole increases expression ISO RGD:732293 6480464 propiconazole results in increased expression of CHEK1 mRNA CTD PMID:21278054 resveratrol increases expression EXP   6480464 resveratrol results in increased expression of CHEK1 mRNA CTD PMID:19167446 resveratrol decreases expression EXP   6480464 resveratrol results in decreased expression of CHEK1 mRNA CTD PMID:18089832 resveratrol affects expression EXP   6480464 resveratrol affects the expression of CHEK1 protein CTD PMID:18089832 resveratrol multiple interactions EXP   6480464 [Coumestrol co-treated with resveratrol] results in increased expression of CHEK1 mRNA CTD PMID:19167446 resveratrol multiple interactions EXP   6480464 Caffeine inhibits the reaction [[resveratrol results in increased activity of [ATM protein co-treated with ATR protein]] results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]]; more ... CTD PMID:15975956 rotenone increases expression EXP   6480464 Rotenone results in increased expression of CHEK1 mRNA CTD PMID:18191903 saccharin increases expression ISO RGD:732293 6480464 Saccharin results in increased expression of CHEK1 mRNA CTD PMID:19000923 silver(1+) nitrate increases expression EXP   6480464 Silver Nitrate analog results in increased expression of CHEK1 mRNA CTD PMID:22831968 styrene oxide increases expression ISO RGD:732293 6480464 styrene oxide results in increased expression of CHEK1 protein CTD PMID:20025956 succimer multiple interactions ISO RGD:732293 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of CHEK1 mRNA CTD PMID:21641980 tamoxifen affects expression ISO RGD:732293 6480464 Tamoxifen affects the expression of CHEK1 mRNA CTD PMID:17555576 temozolomide increases phosphorylation EXP   6480464 temozolomide results in increased phosphorylation of CHEK1 protein CTD PMID:15930307 tert-butyl hydroperoxide decreases expression EXP   6480464 tert-Butylhydroperoxide results in decreased expression of CHEK1 mRNA CTD PMID:12414654 thioacetamide increases expression ISO RGD:620545 6480464 Thioacetamide results in increased expression of CHEK1 mRNA CTD PMID:22659510 thioacetamide increases phosphorylation ISO RGD:620545 6480464 Thioacetamide results in increased phosphorylation of CHEK1 protein CTD PMID:22659510 trans-resveratrol increases expression EXP   6480464 resveratrol results in increased expression of CHEK1 mRNA CTD PMID:19167446 trans-resveratrol decreases expression EXP   6480464 resveratrol results in decreased expression of CHEK1 mRNA CTD PMID:18089832 trans-resveratrol affects expression EXP   6480464 resveratrol affects the expression of CHEK1 protein CTD PMID:18089832 trans-resveratrol multiple interactions EXP   6480464 [Coumestrol co-treated with resveratrol] results in increased expression of CHEK1 mRNA CTD PMID:19167446 trans-resveratrol multiple interactions EXP   6480464 Caffeine inhibits the reaction [[resveratrol results in increased activity of [ATM protein co-treated with ATR protein]] results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]]; more ... CTD PMID:15975956 trimellitic anhydride increases expression ISO RGD:732293 6480464 trimellitic anhydride results in increased expression of CHEK1 mRNA CTD PMID:19042947 troglitazone decreases expression EXP   6480464 troglitazone results in decreased expression of CHEK1 mRNA CTD PMID:19140230 valproic acid decreases expression EXP   6480464 Valproic Acid results in decreased expression of CHEK1 mRNA CTD PMID:20585447 wortmannin multiple interactions EXP   6480464 wortmannin inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein] CTD PMID:19261750 wortmannin multiple interactions EXP   6480464 wortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK1 protein] CTD PMID:22119920 wortmannin decreases expression EXP   6480464 wortmannin results in decreased expression of CHEK1 protein CTD PMID:22409540 zidovudine increases phosphorylation EXP   6480464 Zidovudine results in increased phosphorylation of CHEK1 protein CTD PMID:19541796 zidovudine decreases expression EXP   6480464 Zidovudine results in decreased expression of CHEK1 protein CTD PMID:19541796 zinc dichloride increases expression ISO RGD:732293 6480464 zinc chloride results in increased expression of CHEK1 mRNA CTD PMID:19000923 Gene Ontology Annotations Biological Process Term Qualifier Evidence With Reference Notes Source Original Reference(s) cell cycle checkpoint   TAS   2290271 Reactome:REACT_1538 Reactome Reactome:REACT_1538 cellular response to caffeine   IEA Ensembl:ENSRNOP00000011226 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 cellular response to mechanical stimulus   IEP   2290271 PMID:19593445 UniProtKB PMID:19593445 chromatin-mediated maintenance of transcription   ISS UniProtKB:O35280 2290271 GO_REF:0000024 UniProtKB GO_REF:0000024 chromatin-mediated maintenance of transcription   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 DNA damage checkpoint   IDA   2290271 PMID:16963448 UniProtKB PMID:16963448 DNA damage checkpoint   IMP   2290271 PMID:19716789 UniProtKB PMID:19716789 DNA damage induced protein phosphorylation   IDA   2290271 PMID:16963448 UniProtKB PMID:16963448 DNA damage induced protein phosphorylation   IEA Ensembl:ENSRNOP00000011226 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 DNA repair   IMP   2290271 PMID:19716789 UniProtKB PMID:19716789 DNA repair   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 DNA replication   TAS   2290271 Reactome:REACT_6769 Reactome Reactome:REACT_6769 G2 DNA damage checkpoint   IMP   2290271 PMID:20932473 UniProtKB PMID:20932473 G2 DNA damage checkpoint   IEA Ensembl:ENSRNOP00000011226 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 G2/M transition of mitotic cell cycle   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 histone H3-T11 phosphorylation   IDA   2290271 PMID:18243098 GOC PMID:18243098 negative regulation of mitosis   IDA   2290271 PMID:15311285 UniProtKB PMID:15311285 peptidyl-threonine phosphorylation   IDA   2290271 PMID:15665856 UniProtKB PMID:15665856 regulation of cell proliferation   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 regulation of double-strand break repair via homologous recombination   IDA   2290271 PMID:15665856 UniProtKB PMID:15665856 regulation of histone H3-K9 acetylation   ISS UniProtKB:O35280 2290271 GO_REF:0000024 UniProtKB GO_REF:0000024 regulation of histone H3-K9 acetylation   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 regulation of mitotic centrosome separation   IDA   2290271 PMID:15311285 UniProtKB PMID:15311285 regulation of S phase   IEA Ensembl:ENSRNOP00000011226 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage   ISS UniProtKB:O35280 2290271 GO_REF:0000024 UniProtKB GO_REF:0000024 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 replicative senescence   NAS   2290271 PMID:15149599 BHF-UCL PMID:15149599 response to DNA damage stimulus   IMP   2290271 PMID:20932473 UniProtKB PMID:20932473 Cellular Component Term Qualifier Evidence With Reference Notes Source Original Reference(s) centrosome   IDA   2290271 PMID:15311285 UniProtKB PMID:15311285 chromatin   ISS UniProtKB:O35280 2290271 GO_REF:0000024 UniProtKB GO_REF:0000024 chromatin   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 chromosome, telomeric region colocalizes_with IDA   2290271 PMID:15149599 BHF-UCL PMID:15149599 condensed nuclear chromosome   IDA   2290271 PMID:9382850 UniProtKB PMID:9382850 cytosol   TAS   2290271 Reactome:REACT_111221 Reactome Reactome:REACT_111221 nucleoplasm   TAS   2290271 Reactome:REACT_1170 Reactome Reactome:REACT_1170 nucleoplasm   TAS   2290271 Reactome:REACT_845 Reactome Reactome:REACT_845 nucleoplasm   TAS   2290271 Reactome:REACT_6869 Reactome Reactome:REACT_6869 nucleus   IDA   2290271 PMID:15311285 UniProtKB PMID:15311285 nucleus   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 nucleus   IDA   2290271 PMID:20932473 UniProtKB PMID:20932473 replication fork   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 Molecular Function Term Qualifier Evidence With Reference Notes Source Original Reference(s) ATP binding   IEA UniProtKB-KW:KW-0067 2290271 GO_REF:0000037 UniProtKB GO_REF:0000037 ATP binding   IEA InterPro:IPR000719|InterPro:IPR017441 2290271 GO_REF:0000002 InterPro GO_REF:0000002 ATP binding   IEA InterPro:IPR000719 2290271 GO_REF:0000002 InterPro GO_REF:0000002 ATP binding   IEA UniProtKB-KW:KW-0067 2290271 GO_REF:0000038 UniProtKB GO_REF:0000038 histone kinase activity (H3-T11 specific)   IDA   2290271 PMID:18243098 UniProtKB PMID:18243098 histone kinase activity (H3-T11 specific)   IEA Ensembl:ENSMUSP00000034625 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 protein binding   IPI UniProtKB:P08238 2290271 PMID:16330544 IntAct PMID:16330544 protein binding   IPI UniProtKB:P08238 2290271 PMID:22939624 IntAct PMID:22939624 protein binding   IPI UniProtKB:Q9NRD1 2290271 PMID:19716789 UniProtKB PMID:19716789 protein binding   IPI UniProtKB:Q9UK73 2290271 PMID:19330022 UniProtKB PMID:19330022 protein binding   IPI UniProtKB:Q9HAW4 2290271 PMID:16963448 IntAct PMID:16963448 protein binding   IPI UniProtKB:P30307 2290271 PMID:16330544 IntAct PMID:16330544 protein binding   IPI UniProtKB:Q9UNS1 2290271 PMID:15798197 IntAct PMID:15798197 protein binding   IPI UniProtKB:Q06609 2290271 PMID:15665856 IntAct PMID:15665856 protein binding   IPI UniProtKB:P38398 2290271 PMID:11836499 IntAct PMID:11836499 protein binding   IPI UniProtKB:P30307 2290271 PMID:11836499 IntAct PMID:11836499 protein serine/threonine kinase activity   IEA InterPro:IPR008271 2290271 GO_REF:0000002 InterPro GO_REF:0000002 protein serine/threonine kinase activity   IDA   2290271 PMID:16963448 UniProtKB PMID:16963448 Molecular Pathway Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) cell cycle pathway, mitotic   IEA RGD:732292 6907045   KEGG hsa:04110 G2/M DNA damage checkpoint pathway   ISS RGD:620545 2316109   RGD   p53 signaling pathway   TAS   2316155   RGD   p53 signaling pathway   IEA RGD:732292 6907045   KEGG hsa:04115 p53 signaling pathway   EXP   6484113   PID PID:200206 p53 signaling pathway   TAS   2316156   RGD   External Database Links KEGG Pathway Cell cycle HTLV-I infection p53 signaling pathway Viral carcinogenesis Pathway Interaction Database ATR signaling pathway (PID:200038) Circadian rhythm pathway (PID:200081) Fanconi anemia pathway (PID:200002) p53 pathway (PID:200206) p73 transcription factor network (PID:200017) Disease Annotations Neoplasm Metastasis  (IEP) Pancreatic Neoplasms  (IAGP) Gene-Chemical Interaction Annotations 1,3-dinitrobenzene  (ISO) 17alpha-ethynylestradiol  (ISO) 17beta-estradiol  (EXP,ISO) 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP) 2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO) 2,6-di-tert-butyl-4-methylphenol  (ISO) 2-methylcholine  (EXP) 3,3',5-triiodo-L-thyronine  (EXP) 3,4-methylenedioxymethamphetamine  (ISO) 4-hydroxynon-2-enal  (ISO) 5-aza-2'-deoxycytidine  (EXP) 5-fluoro-2'-deoxyuridine  (EXP) 5-fluorouracil  (EXP,ISO) 7,12-dimethyltetraphene  (ISO) acrylamide  (ISO) aflatoxin B1  (EXP) all-trans-retinoic acid  (EXP,ISO) ammonium chloride  (ISO) anthracene-1,8,9-triol  (ISO) aphidicolin  (ISO) benzo[a]pyrene  (EXP,ISO) bis(2-chloroethyl) sulfide  (EXP) bisphenol A  (EXP) busulfan  (EXP) caffeine  (EXP,ISO) carmustine  (EXP) catechol  (ISO) cefaloridine  (ISO) chlorpyrifos  (ISO) cholic acid  (ISO) choline  (EXP,ISO) ciprofloxacin  (ISO) cisplatin  (EXP,ISO) clofarabine  (EXP) clofibrate  (ISO) cobalt dichloride  (EXP) copper atom  (EXP,ISO) copper(0)  (EXP,ISO) copper(2+) sulfate  (EXP) coumestrol  (EXP) curcumin  (EXP) cyclosporin A  (EXP) diarsenic trioxide  (EXP,ISO) dibutyl phthalate  (ISO) digitoxin  (EXP) doxorubicin  (EXP) etoposide  (EXP) fenofibrate  (ISO) folic acid  (EXP,ISO) furan  (ISO) furosemide  (ISO) genistein  (EXP) Goe 6976  (EXP) hydrogen peroxide  (EXP) hydroxyurea  (EXP,ISO) indole-3-methanol  (ISO) iron dichloride  (ISO) iron trichloride  (ISO) isoflurane  (ISO) L-methionine  (ISO) lead diacetate  (ISO) leptomycin B  (EXP) lovastatin  (EXP) menadione  (EXP) methyl isocyanate  (ISO) methylmercury chloride  (ISO) N-acetyl-L-cysteine  (EXP) N-nitrosodiethylamine  (ISO) ochratoxin A  (ISO) ozone  (ISO) paclitaxel  (ISO) paracetamol  (ISO) phorbol 13-acetate 12-myristate  (ISO) pirinixic acid  (ISO) platinum  (EXP) platinum(0)  (EXP) propiconazole  (ISO) resveratrol  (EXP) rotenone  (EXP) saccharin  (ISO) silver(1+) nitrate  (EXP) styrene oxide  (ISO) succimer  (ISO) tamoxifen  (ISO) temozolomide  (EXP) tert-butyl hydroperoxide  (EXP) thioacetamide  (ISO) trans-resveratrol  (EXP) trimellitic anhydride  (ISO) troglitazone  (EXP) valproic acid  (EXP) wortmannin  (EXP) zidovudine  (EXP) zinc dichloride  (ISO) Gene Ontology Annotations Biological Process cell cycle checkpoint  (TAS) cellular response to caffeine  (IEA) cellular response to mechanical stimulus  (IEP) chromatin-mediated maintenance of transcription  (IEA,ISS) DNA damage checkpoint  (IDA,IMP) DNA damage induced protein phosphorylation  (IDA,IEA) DNA repair  (IEA,IMP) DNA replication  (TAS) G2 DNA damage checkpoint  (IEA,IMP) G2/M transition of mitotic cell cycle  (IEA) histone H3-T11 phosphorylation  (IDA) negative regulation of mitosis  (IDA) peptidyl-threonine phosphorylation  (IDA) regulation of cell proliferation  (IEA) regulation of double-strand break repair via homologous recombination  (IDA) regulation of histone H3-K9 acetylation  (IEA,ISS) regulation of mitotic centrosome separation  (IDA) regulation of S phase  (IEA) regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage  (IEA,ISS) replicative senescence  (NAS) response to DNA damage stimulus  (IMP) Cellular Component centrosome  (IDA) chromatin  (IEA,ISS) chromosome, telomeric region  (IDA) condensed nuclear chromosome  (IDA) cytosol  (TAS) nucleoplasm  (TAS) nucleus  (IDA,IEA) replication fork  (IEA) Molecular Function ATP binding  (IEA) histone kinase activity (H3-T11 specific)  (IDA,IEA) protein binding  (IPI) protein serine/threonine kinase activity  (IDA,IEA) Molecular Pathway Annotations cell cycle pathway, mitotic  (IEA) G2/M DNA damage checkpoint pathway  (ISS) p53 signaling pathway  (EXP,IEA,TAS) External Database Links KEGG Pathway Cell cycle HTLV-I infection p53 signaling pathway Viral carcinogenesis Pathway Interaction Database ATR signaling pathway (PID:200038) Circadian rhythm pathway (PID:200081) Fanconi anemia pathway (PID:200002) p53 pathway (PID:200206) p73 transcription factor network (PID:200017) References - curated 1. GOA_HUMAN data from the GO Consortium 2. Hansel DE, etal., Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6152-8. 3. Hu B, etal., J Biol Chem. 2001 May 25;276(21):17693-8. Epub 2001 Mar 7. 4. Kruse JP and Gu W, Cell. 2009 May 15;137(4):609-22. 5. Lavin MF and Gueven N, Cell Death Differ. 2006 Jun;13(6):941-50. 6. Okazaki T, etal., Clin Cancer Res. 2008 Apr 1;14(7):2042-8. 7. Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology 8. Pipeline to import Pathway Interaction Database annotations from NCI into RGD 9. RGD automated import pipeline for gene-chemical interactions References - uncurated PubMed 10557092   10608806   10673501   10681541   10717241   10761933   10859164   11016625   11252893   11329013   11333986   11390642   11535615   11551930   11709713   11799067   11821419   11836499   11896572   11912127   12062056   12150968   12244092   12399544   12446774   12477932   12588868   12660173   12676583   12676925   12676962   12738771   12756247   12759351   12766152   12791699   12791985   12813133   12902976   12955071   12959929   12963847   14504477   14559997   14570880   14624239   14657349   14681206   14681223   14759516   14988723   15149599   15220350   15225637   15279790   15311285   15324660   15326376   15342556   15364958   15489334   15526025   15539958   15601819   15647386   15650047   15655357   15659650   15665856   15688426   15699047   15705874   15707391   15710331   15735702   15743907   15761153   15775976   15798197   15831461   15870257   15961392   15974586   16123041   16137618   16159883   16163388   16217032   16280359   16306615   16330544   16344560   16414312   16501606   16511572   16581803   16619043   16629900   16649252   16652144   16705183   16732333   16783362   16828751   16873548   16880517   16885021   16912045   16927022   16951182   16963448   17003105   17015476   17035231   17102638   17106257   17157788   17210576   17274954   17276342   17290223   17292828   17296736   17370265   17380128   17408908   17464182   17468739   17491592   17544403   17611684   17638866   17684142   17716975   17726372   17879369   17912454   17962807   17986860   17991895   18029388   18071310   18088187   18159231   18229454   18239674   18243098   18247328   18270339   18317453   18331829   18339864   18346918   18424430   18434539   18448427   18451105   18469532   18480045   18495871   18550533   18566216   18614046   18632613   18642443   18671143   18676680   18698031   18723495   18820127   18950845   18983824   19060337   19064565   19064572   19091954   19119425   19124506   19170196   19177015   19242509   19270516   19275579   19276361   19330022   19401701   19453842   19473886   19477924   19487575   19546241   19570909   19584159   19593445   19615254   19625176   19628579   19690177   19692168   19694479   19714462   19716789   19743875   19778378   19808933   19828454   19837665   19838212   19843865   19861535   19903823   19931269   20029092   20053681   20068082   20090422   20123862   20146081   20159774   20233725   20360068   20453000   20495005   20496165   20508983   20514472   20562859   20567916   20581453   20599444   20609246   20616048   20639859   20644561   20716119   20719863   20731661   20805465   20940144   20969866   21034966   21051833   21118956   21139048   21145461   21154811   21171266   21173116   21179472   21212274   21301228   21383502   21389083   21401699   21440578   21502314   21532626   21557990   21566061   21615992   21628425   21680529   21752283   21803008   21832049   21845734   21858151   21890473   21906983   21907702   21921034   21988832   21995812   22044003   22080164   22106282   22134241   22159421   22184239   22203733   22231448   22318606   22357623   22401965   22433954   22435685   22505024   22505724   22529391   22553144   22556425   22585575   22621920   22692200   22743332   22855742   22863316   22939624   22939629   22942255   23000965   23068608   23085068   23109433   23269272   23383273   8889549   9278511   9278512   9382850   9765199 RGD Disease Portals CHEK1 has been annotated in the following RGD Disease Portals. Biological Process Cancer Diseases Cancer Pathways Cardiovascular Pathways Diabetes Pathways Immune and Inflammatory Pathways Neurological Pathways Obesity Pathways Respiratory Pathways Genomics Comparative Map Data CHEK1   (Homo sapiens) Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI Human Genome Assembly Build 36 11 125,001,547 - 125,030,847 + NCBI Human Cytogenetic Map 11 q24.2   NCBI Human Genome Assembly 11 125,001,546 - 125,030,847   NCBI Chek1   (Mus musculus) Map Chr Position Strand Source Mouse Genome Assembly GRCm38 9 36,708,482 - 36,726,658 - NCBI Mouse cM Map 9   - NCBI Mouse Celera Assembly 9 33,911,337 - 33,929,618 - NCBI Mouse Genome Assembly Build 37 9 36,516,067 - 36,534,243 - NCBI Mouse Genome Assembly Build 36.1 9 36,516,067 - 36,534,212 - NCBI Mouse Cytogenetic Map 9 A5.3   NCBI Chek1   (Rattus norvegicus) Map Chr Position Strand Source Rat Cytogenetic Map 8 q21   NCBI RGSC Genome Assembly v5.0 8 39,184,020 - 39,204,446 - NCBI RGSC Genome Assembly v3.4 8 37,954,322 - 37,974,748 - NCBI Rat Celera Assembly 8 38,000,251 - 38,020,582 + NCBI Genome Assembly 3.1 8 37,963,088 - 37,983,514 - NCBI Position Markers RH17743   Map Chr Position Strand Source Human GeneMap99-GB4 RH Map 11 415.6   UniSTS Human Genome Assembly HuRef 11 121,483,831 - 121,483,951   UniSTS Human Genome Assembly GRCh37 11 125,542,453 - 125,542,573   UniSTS Human Celera Assembly 11 122,702,703 - 122,702,823   RGD Human Genome Assembly Build 36 11 125,047,663 - 125,047,783   RGD Human Cytogenetic Map 11 q24.2   UniSTS D11S2092   Map Chr Position Strand Source Human Genome Assembly HuRef 11 121,470,789 - 121,470,948   UniSTS Human Genome Assembly GRCh37 11 125,529,411 - 125,529,570   UniSTS Human Celera Assembly 11 122,689,659 - 122,689,818   RGD Human Genome Assembly Build 36 11 125,034,621 - 125,034,780   RGD Human Cytogenetic Map 11 q24.2   UniSTS RH92593   Map Chr Position Strand Source Human GeneMap99-GB4 RH Map 11 415.6   UniSTS Human Genome Assembly HuRef 11 121,436,525 - 121,436,654   UniSTS Human Genome Assembly GRCh37 11 125,495,159 - 125,495,288   UniSTS Human Celera Assembly 11 122,655,469 - 122,655,598   RGD Human Genome Assembly Build 36 11 125,000,369 - 125,000,498   RGD Human Cytogenetic Map 11 q24.2   UniSTS RH122396   Map Chr Position Strand Source Human TNG Radiation Hybrid Map 11 58915.0   UniSTS Human Genome Assembly HuRef 11 121,442,344 - 121,442,618   UniSTS Human Genome Assembly GRCh37 11 125,500,977 - 125,501,251   UniSTS Human Celera Assembly 11 122,661,287 - 122,661,561   RGD Human Genome Assembly Build 36 11 125,006,187 - 125,006,461   RGD Human Cytogenetic Map 11 q24.2   UniSTS A006U05   Map Chr Position Strand Source Human GeneMap99-GB4 RH Map 11 415.6   UniSTS Human Genome Assembly HuRef 11 121,468,177 - 121,468,283   UniSTS Human Genome Assembly GRCh37 11 125,526,799 - 125,526,905   UniSTS Human Celera Assembly 11 122,687,112 - 122,687,218   RGD Human Genome Assembly Build 36 11 125,032,009 - 125,032,115   RGD Human Cytogenetic Map 11 q24.2   UniSTS ACRV1_8189   Map Chr Position Strand Source Human Genome Assembly HuRef 11 121,483,421 - 121,483,945   UniSTS Human Genome Assembly GRCh37 11 125,542,043 - 125,542,567   UniSTS Human Celera Assembly 11 122,702,293 - 122,702,817   RGD Human Genome Assembly Build 36 11 125,047,253 - 125,047,777   RGD RH36540   Map Chr Position Strand Source Human GeneMap99-GB4 RH Map 11 415.6   UniSTS Human Genome Assembly HuRef 11 121,468,191 - 121,468,314   UniSTS Human Genome Assembly GRCh37 11 125,526,813 - 125,526,936   UniSTS Human Celera Assembly 11 122,687,126 - 122,687,249   RGD Human Genome Assembly Build 36 11 125,032,023 - 125,032,146   RGD Human Cytogenetic Map 11 q24.2   UniSTS RH66419   Map Chr Position Strand Source Human GeneMap99-GB4 RH Map 11 415.6   UniSTS Human Genome Assembly HuRef 11 121,471,766 - 121,471,845   UniSTS Human Genome Assembly GRCh37 11 125,530,388 - 125,530,467   UniSTS Human Celera Assembly 11 122,690,636 - 122,690,715   RGD Human Genome Assembly Build 36 11 125,035,598 - 125,035,677   RGD Human Cytogenetic Map 11 q24.2   UniSTS WI-7841   Map Chr Position Strand Source Human NCBI RH Map 11 1060.4   UniSTS Human Whitehead-YAC Contig Map 11     UniSTS Human Whitehead-RH Map 11 582.5   UniSTS Human GeneMap99-GB4 RH Map 11 416.22   UniSTS Human Genome Assembly HuRef 11 121,483,653 - 121,483,854   UniSTS Human Genome Assembly GRCh37 11 125,542,275 - 125,542,476   UniSTS Human Celera Assembly 11 122,702,525 - 122,702,726   RGD Human Genome Assembly Build 36 11 125,047,485 - 125,047,686   RGD Human Cytogenetic Map 11 q24.2   UniSTS ACRV1   Map Chr Position Strand Source Human GeneMap99-GB4 RH Map 11 415.6   UniSTS Human Genome Assembly HuRef 11 121,483,653 - 121,483,855   UniSTS Human Genome Assembly GRCh37 11 125,542,275 - 125,542,477   UniSTS Human Celera Assembly 11 122,702,525 - 122,702,727   RGD Human Genome Assembly Build 36 11 125,047,485 - 125,047,687   RGD Human Cytogenetic Map 11 q24.2   UniSTS D8S2279   Map Chr Position Strand Source Human Cytogenetic Map 21 q22.12   UniSTS Human Cytogenetic Map 15 q13   UniSTS Human Cytogenetic Map 9 q32   UniSTS Human Cytogenetic Map 15 q22.3   UniSTS Human Cytogenetic Map 17 p12   UniSTS Human Cytogenetic Map 21 q21.3   UniSTS Human Cytogenetic Map 3 p22-p21.3   UniSTS Human Cytogenetic Map 1 q21.1   UniSTS Human Cytogenetic Map 2 q24.2   UniSTS Human Cytogenetic Map 17 q24.2   UniSTS Human Cytogenetic Map 1 q32   UniSTS Human Cytogenetic Map 3 p25.3   UniSTS Human Cytogenetic Map 20 q13.3   UniSTS Human Cytogenetic Map 2 q31.1   UniSTS Human Cytogenetic Map 1 q21   UniSTS Human Cytogenetic Map 3 p14.1   UniSTS Human Cytogenetic Map 2 q37.3   UniSTS Human Cytogenetic Map 7 p14.1   UniSTS Human Cytogenetic Map 2 q22.3   UniSTS Human Cytogenetic Map 15 q13.2   UniSTS Human Cytogenetic Map 12 q24.1   UniSTS Human Cytogenetic Map 7 p15.2   UniSTS Human Cytogenetic Map 5 q31.2   UniSTS Human Cytogenetic Map 2 p25.2   UniSTS Human Cytogenetic Map 3 p24.3   UniSTS Human Cytogenetic Map 17 q25.3   UniSTS Human Cytogenetic Map 15 q22.31   UniSTS Human Cytogenetic Map 5 q14   UniSTS Human Cytogenetic Map 5 q31   UniSTS Human Cytogenetic Map 1 p36.32   UniSTS Human Cytogenetic Map 1 q42.12   UniSTS Human Cytogenetic Map 7 q21.11   UniSTS Human Cytogenetic Map 9 q34.2   UniSTS Human Cytogenetic Map 19 q13.3   UniSTS Human Cytogenetic Map 22 q13.33   UniSTS Human Cytogenetic Map 8 q22.3   UniSTS Human Cytogenetic Map 6 p21.1-p12   UniSTS Human Cytogenetic Map 1 p36.13   UniSTS Human Cytogenetic Map 7 q36.3   UniSTS Human Cytogenetic Map 2 p25.1   UniSTS Human Cytogenetic Map 7 p21.3   UniSTS Human Cytogenetic Map 4 q12   UniSTS Human Cytogenetic Map 22 q11.22   UniSTS Human Cytogenetic Map 11 p13   UniSTS Human Cytogenetic Map 1 q12   UniSTS Human Cytogenetic Map 8 p23   UniSTS Human Cytogenetic Map 11 q13.2-q13.3   UniSTS Human Cytogenetic Map 13 q14.1-q14.3   UniSTS Human Cytogenetic Map 3 q22-q24   UniSTS Human Cytogenetic Map 3 q13.1-q13.2   UniSTS Human Cytogenetic Map 16 q24   UniSTS Human Cytogenetic Map 5 q23.3-q31.1   UniSTS Human Cytogenetic Map 8 p21.3   UniSTS Human Cytogenetic Map 14 q32.3   UniSTS Human Cytogenetic Map 7 q11.23   UniSTS Human Cytogenetic Map 7 q32   UniSTS Human Cytogenetic Map 14 q32.33   UniSTS Human Cytogenetic Map 19 p13.2   UniSTS Human Cytogenetic Map 9 q34.3   UniSTS Human Cytogenetic Map 1 p32.3   UniSTS Human Cytogenetic Map 17 q11   UniSTS Human Cytogenetic Map 17 p13.1-p12   UniSTS Human Cytogenetic Map 18 q21.33   UniSTS Human Cytogenetic Map 19 p13.12   UniSTS Human Cytogenetic Map 5 q14.1   UniSTS Human Cytogenetic Map 14 q24.3   UniSTS Human Cytogenetic Map 1 q21-q23   UniSTS Human Cytogenetic Map X p11.23   UniSTS Human Cytogenetic Map 4 q21.1   UniSTS Human Cytogenetic Map 12 q13.13   UniSTS Human Cytogenetic Map 14 q23.3   UniSTS Human Cytogenetic Map 17 p12-p11.2   UniSTS Human Cytogenetic Map 6 p21.1   UniSTS Human Cytogenetic Map 1 q24   UniSTS Human Cytogenetic Map 1 q43   UniSTS Human Cytogenetic Map 9 q34.13   UniSTS Human Cytogenetic Map 19 q13.4   UniSTS Human Cytogenetic Map 2 q32   UniSTS Human Cytogenetic Map X p22.2   UniSTS Human Cytogenetic Map 19 p13.11   UniSTS Human Cytogenetic Map 2 q33   UniSTS Human Cytogenetic Map 10 p13   UniSTS Human Cytogenetic Map 2 q11.2   UniSTS Human Cytogenetic Map 3 q27   UniSTS Human Cytogenetic Map 17 q25.1   UniSTS Human Cytogenetic Map 4 p16.1   UniSTS Human Cytogenetic Map 14 q22.3   UniSTS Human Cytogenetic Map 10 q23-q24   UniSTS Human Cytogenetic Map 2 q37.1   UniSTS Human Cytogenetic Map 17 q12   UniSTS Human Cytogenetic Map 14 q31-q32   UniSTS Human Cytogenetic Map 5 p15.33   UniSTS Human Cytogenetic Map 1 q23.2   UniSTS Human Cytogenetic Map 16 q24.3   UniSTS Human Cytogenetic Map 4 p14   UniSTS Human Cytogenetic Map 2 q32.3   UniSTS Human Cytogenetic Map 15 q21.1   UniSTS Human Cytogenetic Map 4 q32.2   UniSTS Human Cytogenetic Map 10 q23   UniSTS Human Cytogenetic Map 5 q14.2   UniSTS Human Cytogenetic Map 4 q32.1   UniSTS Human Cytogenetic Map 1 q25.1   UniSTS Human Cytogenetic Map 11 q14.1   UniSTS Human Cytogenetic Map 4 p16.3   UniSTS Human Cytogenetic Map 1 p34.2   UniSTS Human Cytogenetic Map 11 q23.1   UniSTS Human Cytogenetic Map 3 p21.1   UniSTS Human Cytogenetic Map 16 q22.2   UniSTS Human Cytogenetic Map 14 q32.31   UniSTS Human Cytogenetic Map 16 q11.2   UniSTS Human Cytogenetic Map 6 q22   UniSTS Human Cytogenetic Map 10 p15.3   UniSTS Human Cytogenetic Map 11 q23   UniSTS Human Cytogenetic Map 22 q13.2   UniSTS Human Cytogenetic Map 12 q12   UniSTS Human Cytogenetic Map 19 q13.42   UniSTS Human Cytogenetic Map 19 q13.11   UniSTS Human Cytogenetic Map 12 q24.31   UniSTS Human Cytogenetic Map 15 q15   UniSTS Human Cytogenetic Map 2 q33.1   UniSTS Human Cytogenetic Map 22 q12.3   UniSTS Human Cytogenetic Map 20 q11   UniSTS Human Cytogenetic Map 22 q11.23   UniSTS Human Cytogenetic Map 17 q25   UniSTS Human Cytogenetic Map 1 p13.3   UniSTS Human Cytogenetic Map 3 p22.1   UniSTS Human Cytogenetic Map 8 q22.1   UniSTS Human Cytogenetic Map 16 q22.1   UniSTS Human Cytogenetic Map 18 p11.31   UniSTS Human Cytogenetic Map 19 p12   UniSTS Human Cytogenetic Map 11 q13.1   UniSTS Human Cytogenetic Map 19 p13.3   UniSTS Human Cytogenetic Map 2 p22.1   UniSTS Human Cytogenetic Map 16 p13.3   UniSTS Human Cytogenetic Map 1 p35.2   UniSTS Human Cytogenetic Map Y p11.2   UniSTS Human Cytogenetic Map 13 q13.1   UniSTS Human Cytogenetic Map 20 q11.22   UniSTS Human Cytogenetic Map 19 q13.2   UniSTS Human Cytogenetic Map 18 q12   UniSTS Human Cytogenetic Map 17 q21.33   UniSTS Human Cytogenetic Map 15 q15.1   UniSTS Human Cytogenetic Map 3 q27.2   UniSTS Human Cytogenetic Map 3 q21.3   UniSTS Human Cytogenetic Map 5 p15.2   UniSTS Human Cytogenetic Map 20 q13.12   UniSTS Human Cytogenetic Map 17 q21   UniSTS Human Cytogenetic Map 1 q42   UniSTS Human Cytogenetic Map 14 q32.11   UniSTS Human Cytogenetic Map 17 q21.2-q21.3   UniSTS Human Cytogenetic Map 5 q32-q34   UniSTS Human Cytogenetic Map 15 q14   UniSTS Human Cytogenetic Map 16 q13   UniSTS Human Cytogenetic Map 3 q21.2   UniSTS Human Cytogenetic Map 3 p21.3   UniSTS Human Cytogenetic Map 14 q24.2   UniSTS Human Cytogenetic Map 12 q24.13   UniSTS Human Cytogenetic Map 13 q14.11   UniSTS Human Cytogenetic Map 3 q27.3   UniSTS Human Cytogenetic Map 1 q32.3   UniSTS Human Cytogenetic Map 6 p22.1   UniSTS Human Cytogenetic Map 9 q34.11   UniSTS Human Cytogenetic Map 6 q21   UniSTS Human Cytogenetic Map 6 q25.3   UniSTS Human Cytogenetic Map 2 p11.2   UniSTS Human Cytogenetic Map 13 q14.3   UniSTS Human Cytogenetic Map 17 q11.2   UniSTS Human Cytogenetic Map 10 p12   UniSTS Human Cytogenetic Map 2 q33.3   UniSTS Human Cytogenetic Map 14 q21.3   UniSTS Human Cytogenetic Map 8 p22-p21   UniSTS Human Cytogenetic Map 18 q11.2   UniSTS Human Cytogenetic Map 2 p15   UniSTS Human Cytogenetic Map 17 q22   UniSTS Human Cytogenetic Map 12 q21.33   UniSTS Human Cytogenetic Map 20 q13.32   UniSTS Human Cytogenetic Map 1 p34.1   UniSTS Human Cytogenetic Map 10 q26   UniSTS Human Cytogenetic Map 8 p23.1   UniSTS Human Cytogenetic Map 19 p13   UniSTS Human Cytogenetic Map 7 q21.13   UniSTS Human Cytogenetic Map 7 q31.1   UniSTS Human Cytogenetic Map 1 p33   UniSTS Human Cytogenetic Map 21 q22.3   UniSTS Human Cytogenetic Map 1 p35.1   UniSTS Human Cytogenetic Map 22 q12.2   UniSTS Human Cytogenetic Map 9 q22.3   UniSTS Human Cytogenetic Map 8 q13.1   UniSTS Human Cytogenetic Map 3 q25   UniSTS Human Cytogenetic Map 1 p36.33   UniSTS Human Cytogenetic Map 20 q13.33   UniSTS Human Cytogenetic Map 1 p31.3   UniSTS Human Cytogenetic Map 14 q31.1   UniSTS Human Cytogenetic Map 22 q13.1   UniSTS Human Cytogenetic Map 12 q13.2   UniSTS Human Cytogenetic Map 22 q13.31-q13.33   UniSTS Human Cytogenetic Map 20 q13.31   UniSTS Human Cytogenetic Map 11 p11.2   UniSTS Human Cytogenetic Map 1 q41   UniSTS Human Cytogenetic Map 1 p36.11   UniSTS Human Cytogenetic Map 15 q25.2   UniSTS Human Cytogenetic Map 14 q11.2   UniSTS Human Cytogenetic Map 17 q23.2   UniSTS Human Cytogenetic Map 7 q32.2   UniSTS Human Cytogenetic Map 19 q13.12   UniSTS Human Cytogenetic Map 1 q32.1   UniSTS Human Cytogenetic Map 6 q25.1   UniSTS Human Cytogenetic Map 19 q13.43   UniSTS Human Cytogenetic Map 9 p13.3   UniSTS Human Cytogenetic Map 16 p11.2   UniSTS Human Cytogenetic Map 2 p13.1   UniSTS Human Cytogenetic Map 22 q11.21   UniSTS Human Cytogenetic Map 3 q29   UniSTS Human Cytogenetic Map 7 p13   UniSTS Human Cytogenetic Map 11 q23.3   UniSTS Human Cytogenetic Map 14 q31-q32.1   UniSTS Human Cytogenetic Map 1 q42.11   UniSTS Human Cytogenetic Map 4 q35.1   UniSTS Human Cytogenetic Map 2 p23.3   UniSTS Human Cytogenetic Map 2 p13.3   UniSTS Human Cytogenetic Map X p11.3   UniSTS Human Cytogenetic Map 2 q11.2-q12.1   UniSTS Human Cytogenetic Map 20 q13.13   UniSTS Human Cytogenetic Map 1 p22   UniSTS Human Cytogenetic Map 6 q16.2   UniSTS Human Cytogenetic Map 18 q23   UniSTS Human Cytogenetic Map 2 q14   UniSTS Human Cytogenetic Map 20 p11.23-p11.21   UniSTS Human Cytogenetic Map 16 p12.2   UniSTS Human Cytogenetic Map 8 p11.23   UniSTS Human Cytogenetic Map 19 q13.1   UniSTS Human Cytogenetic Map 19 q13   UniSTS Human Cytogenetic Map 8 p11.21   UniSTS Human Cytogenetic Map 12 q14.3   UniSTS Human Cytogenetic Map X q26.3   UniSTS Human Cytogenetic Map 8 q24.11   UniSTS Human Cytogenetic Map 10 q23.1   UniSTS Human Cytogenetic Map 1 q44   UniSTS Human Cytogenetic Map 9 q22.33   UniSTS Human Cytogenetic Map 3 p21.31   UniSTS Human Cytogenetic Map 17 p13.2   UniSTS Human Cytogenetic Map 9 q21.32   UniSTS Human Cytogenetic Map 7 q34   UniSTS Human Cytogenetic Map 9 q33.3   UniSTS Human Cytogenetic Map 1 p36.1   UniSTS Human Cytogenetic Map 20 q12   UniSTS Human Cytogenetic Map 4 q21.23   UniSTS Human Cytogenetic Map 5 q13.2   UniSTS Human Cytogenetic Map 22 q12.1   UniSTS Human Cytogenetic Map 5 q31.1   UniSTS Human Cytogenetic Map 2 q21.3   UniSTS Human Cytogenetic Map 7 q21.2   UniSTS Human Cytogenetic Map 17 q22.2   UniSTS Human Cytogenetic Map 17 p13   UniSTS Human Cytogenetic Map 12 q24.11   UniSTS Human Cytogenetic Map 18 q21   UniSTS Human Cytogenetic Map 10 q11.1   UniSTS Human Cytogenetic Map 22 q11.2   UniSTS Human Cytogenetic Map 19 q12   UniSTS Human Cytogenetic Map 7 q34-q35   UniSTS Human Cytogenetic Map 15 q24.1   UniSTS Human Cytogenetic Map 18 p11.21   UniSTS Human Cytogenetic Map 1 q23.1   UniSTS Human Cytogenetic Map 19 q13.41   UniSTS Human Cytogenetic Map 6 p25.1-p23   UniSTS Human Cytogenetic Map 11 p15.4   UniSTS Human Cytogenetic Map 10 q22   UniSTS Human Cytogenetic Map 5 q35.3   UniSTS Human Cytogenetic Map 18 q12.1-q21.1   UniSTS Human Cytogenetic Map 12 p13.1   UniSTS Human Cytogenetic Map 13 q12.1   UniSTS Human Cytogenetic Map 12 q15   UniSTS Human Cytogenetic Map 6 p21.32   UniSTS Human Cytogenetic Map 8 q24.3   UniSTS Human Cytogenetic Map 10 p14   UniSTS Human Cytogenetic Map 12 p13.1-p12.3   UniSTS Human Cytogenetic Map 3 p25.2   UniSTS Human Cytogenetic Map 6 p21.33   UniSTS Human Cytogenetic Map 6 p21.3   UniSTS Human Cytogenetic Map 3 p21.2   UniSTS Human Cytogenetic Map 10 q26.3   UniSTS Human Cytogenetic Map 1 q21.3   UniSTS Human Cytogenetic Map X p21.2   UniSTS Human Cytogenetic Map 7 q22.1   UniSTS Human Cytogenetic Map 14 q12   UniSTS Human Cytogenetic Map 8 p11.22   UniSTS Human Cytogenetic Map 19 q13.32   UniSTS Human Cytogenetic Map 2 q21.1   UniSTS Human Cytogenetic Map 9 q21.12   UniSTS Human Cytogenetic Map 15 q23   UniSTS Human Cytogenetic Map 7 p22.2   UniSTS Human Cytogenetic Map 8 p21.2   UniSTS Human Cytogenetic Map 7 q33   UniSTS Human Cytogenetic Map 15 q15.3   UniSTS Human Cytogenetic Map 4 q21.22   UniSTS Human Cytogenetic Map 12 q13.12   UniSTS Human Cytogenetic Map 10 q24.31   UniSTS Human Cytogenetic Map 12 p13.31   UniSTS Human Cytogenetic Map 14 q32.12   UniSTS Human Cytogenetic Map 10 q24.32   UniSTS Human Cytogenetic Map 11 q12.3   UniSTS Human Cytogenetic Map 16 p12.3   UniSTS Human Cytogenetic Map 1 p34.3   UniSTS Human Cytogenetic Map 1 p36.21   UniSTS Human Cytogenetic Map 2 q24.3   UniSTS Human Cytogenetic Map 2 q33.2   UniSTS Human Cytogenetic Map 16 q24.1   UniSTS Human Cytogenetic Map 1 p31.1   UniSTS Human Cytogenetic Map 19 q13.33   UniSTS Human Cytogenetic Map 1 p36.31   UniSTS Human Cytogenetic Map 3 q13.31   UniSTS Human Cytogenetic Map 15 q22.2   UniSTS Human Cytogenetic Map 5 q32   UniSTS Human Cytogenetic Map 6 q13   UniSTS Human Cytogenetic Map X q24   UniSTS Human Cytogenetic Map 6 q25   UniSTS Human Cytogenetic Map 6 p21   UniSTS Human Cytogenetic Map 2 q35   UniSTS Human Cytogenetic Map 12 p13-p12   UniSTS Human Cytogenetic Map 9 p13.2   UniSTS Human Cytogenetic Map 6 p22   UniSTS Human Cytogenetic Map 2 q12.1   UniSTS Human Cytogenetic Map 17 p13.3   UniSTS Human Cytogenetic Map 9 q22.2   UniSTS Human Cytogenetic Map 1 q22   UniSTS Human Cytogenetic Map 1 p22.1   UniSTS Human Cytogenetic Map 1 p36   UniSTS Human Cytogenetic Map 9 q13-q21   UniSTS Human Cytogenetic Map 11 p15.5   UniSTS Human Cytogenetic Map X p11.2   UniSTS Human Cytogenetic Map 19 p   UniSTS Human Cytogenetic Map 19 p13.1-p12   UniSTS Human Cytogenetic Map 7 q22   UniSTS Human Cytogenetic Map 12 q24.33   UniSTS Human Cytogenetic Map 3 q21   UniSTS Human Cytogenetic Map 8 q24   UniSTS Human Cytogenetic Map 18 p11.31-p11.21   UniSTS Human Cytogenetic Map 11 p15.3-p15.1   UniSTS Human Cytogenetic Map 11 q13   UniSTS Human Cytogenetic Map 8 q22   UniSTS Human Cytogenetic Map 4 p15.1   UniSTS Human Cytogenetic Map 1 q25.2   UniSTS Human Cytogenetic Map 2 p16.3   UniSTS Human Cytogenetic Map 16 p13.12   UniSTS Human Cytogenetic Map 7 p21.2   UniSTS Human Cytogenetic Map 12 q21.1   UniSTS Human Cytogenetic Map 2 p14   UniSTS Human Cytogenetic Map 6 q24.3   UniSTS Human Cytogenetic Map 10 q22.2   UniSTS Human Cytogenetic Map 5 q23.1   UniSTS Human Cytogenetic Map 10 q23.2   UniSTS Human Cytogenetic Map 7 p22.3   UniSTS Human Cytogenetic Map 21 q22.2   UniSTS Human Cytogenetic Map 6 q22.1   UniSTS Human Cytogenetic Map 1 q42.1   UniSTS Human Cytogenetic Map 1 q25   UniSTS Human Cytogenetic Map 6 p22.3   UniSTS Human Cytogenetic Map 1 q21.2   UniSTS Human Cytogenetic Map 15 q22.1   UniSTS Human Cytogenetic Map 12 p13.2   UniSTS Human Cytogenetic Map 12 q22   UniSTS Human Cytogenetic Map 3 p21-p12   UniSTS Human Cytogenetic Map 4 q35   UniSTS Human Cytogenetic Map 1 p34-p33   UniSTS Human Cytogenetic Map 21 q22.11   UniSTS Human Cytogenetic Map 3 p22-p21.33   UniSTS Human Cytogenetic Map 3 q23   UniSTS Human Cytogenetic Map 3 q22.1   UniSTS Human Cytogenetic Map 8 q21.11   UniSTS Human Cytogenetic Map X q22.3   UniSTS Human Cytogenetic Map 7 p14   UniSTS Human Cytogenetic Map 17 q21.1   UniSTS Human Cytogenetic Map 15 q21   UniSTS Human Cytogenetic Map 1 q42.3   UniSTS Human Cytogenetic Map 9 q22   UniSTS Human Cytogenetic Map 2 q12.3   UniSTS Human Cytogenetic Map 20 q11.2-q13.2   UniSTS Human Cytogenetic Map 17 q21.31   UniSTS Human Cytogenetic Map 17 q24   UniSTS Human Cytogenetic Map 3 q25.31   UniSTS Human Cytogenetic Map 6 p24.3   UniSTS Human Cytogenetic Map 2 q31.3   UniSTS Human Cytogenetic Map 1 q31   UniSTS Human Cytogenetic Map 7 q32-q33   UniSTS Human Cytogenetic Map 7 q21.1   UniSTS Human Cytogenetic Map 14 q23-q24.2   UniSTS Human Cytogenetic Map 19 q13.3-q13.4   UniSTS Human Cytogenetic Map 2 p24-p21   UniSTS Human Cytogenetic Map 15 q11.2   UniSTS Human Cytogenetic Map 15 q26.3   UniSTS Human Cytogenetic Map 7 p22   UniSTS Human Cytogenetic Map 12 p11   UniSTS Human Cytogenetic Map 1 p35.3   UniSTS Human Cytogenetic Map 1 p12   UniSTS Human Cytogenetic Map 13 q32.3   UniSTS Human Cytogenetic Map 5 q23.3   UniSTS Human Cytogenetic Map 20 q13   UniSTS Human Cytogenetic Map 17 q25.2   UniSTS Human Cytogenetic Map 7 q36.1   UniSTS Human Cytogenetic Map 10 p12.33   UniSTS Human Cytogenetic Map 17 q21.32   UniSTS Human Cytogenetic Map X p11.22   UniSTS Human Cytogenetic Map 12 p13.3   UniSTS Human Cytogenetic Map X q25-q26   UniSTS Human Cytogenetic Map 2 q36.1   UniSTS Human Cytogenetic Map 5 p13   UniSTS Human Cytogenetic Map 15 q25   UniSTS Human Cytogenetic Map 5 q12.1   UniSTS Human Cytogenetic Map 5 p12   UniSTS Human Cytogenetic Map 1 p36.22   UniSTS Human Cytogenetic Map 3 q26.31   UniSTS Human Cytogenetic Map 16 q12   UniSTS Human Cytogenetic Map 17 q22-q23   UniSTS Human Cytogenetic Map X p22.33   UniSTS Human Cytogenetic Map Y p11.3   UniSTS Human Cytogenetic Map 17 p11.2   UniSTS Human Cytogenetic Map X q13.2   UniSTS Human Cytogenetic Map 12 q23.1   UniSTS Human Cytogenetic Map 16 q12.2   UniSTS Human Cytogenetic Map 3 q26.32   UniSTS Human Cytogenetic Map 6 q22.31   UniSTS Human Cytogenetic Map 3 q26.2-q27   UniSTS Human Cytogenetic Map 1 q25.1-q25.2   UniSTS Human Cytogenetic Map 14 q24   UniSTS Human Cytogenetic Map 9 q21.13   UniSTS Human Cytogenetic Map 10 q11.22   UniSTS Human Cytogenetic Map 22 q13.31   UniSTS Human Cytogenetic Map 3 p25.1   UniSTS Human Cytogenetic Map 5 q21.3   UniSTS Human Cytogenetic Map 5 p13.3   UniSTS Human Cytogenetic Map 10 q22.1   UniSTS Human Cytogenetic Map 14 q12-q13   UniSTS Human Cytogenetic Map X p22   UniSTS Human Cytogenetic Map X q23   UniSTS Human Cytogenetic Map 20 p12.3-p11.21   UniSTS Human Cytogenetic Map 2 p21   UniSTS Human Cytogenetic Map 17 q11.2-q12   UniSTS Human Cytogenetic Map 4 q32-q34   UniSTS Human Cytogenetic Map X q25-q26.1   UniSTS Human Cytogenetic Map 2 p25-p24   UniSTS Human Cytogenetic Map 2 p25   UniSTS Human Cytogenetic Map 11 q13.2   UniSTS Human Cytogenetic Map X p22.2-p22.1   UniSTS Human Cytogenetic Map X q22.1   UniSTS Human Cytogenetic Map 4 q25   UniSTS Human Cytogenetic Map 3 p24.2   UniSTS Human Cytogenetic Map 22 q13   UniSTS Human Cytogenetic Map 20 q11.22-q12   UniSTS Human Cytogenetic Map 4 q34.2   UniSTS Human Cytogenetic Map 20 p13   UniSTS Human Cytogenetic Map 22 q13.1-q13.2   UniSTS Human Cytogenetic Map X q28   UniSTS Human Cytogenetic Map 12 q13-q14   UniSTS Human Cytogenetic Map 6 q14.1   UniSTS Human Cytogenetic Map 12 q13.3   UniSTS Human Cytogenetic Map 9 q31.2   UniSTS Human Cytogenetic Map 11 q13.1-q13.2   UniSTS Human Cytogenetic Map 12 q13   UniSTS Human Cytogenetic Map 1 p32-p31   UniSTS Human Cytogenetic Map 21 q21.2   UniSTS Human Cytogenetic Map 10 q24.3   UniSTS Human Cytogenetic Map 16 q21   UniSTS Human Cytogenetic Map 8 q21.1   UniSTS Human Cytogenetic Map 5 p13.2   UniSTS Human Cytogenetic Map 1 p34   UniSTS Human Cytogenetic Map 1 q32.2   UniSTS Human Cytogenetic Map 4 q21.3   UniSTS Human Cytogenetic Map 7 q21-q22   UniSTS Human Cytogenetic Map 3 q26.2   UniSTS Human Cytogenetic Map 2 q36.3   UniSTS Human Cytogenetic Map 8 p22   UniSTS Human Cytogenetic Map 11 q22.1   UniSTS Human Cytogenetic Map 3 q25.33   UniSTS Human Cytogenetic Map 10 q23.31   UniSTS Human Cytogenetic Map 4 p15.32   UniSTS Human Cytogenetic Map 18 q12.2   UniSTS Human Cytogenetic Map 15 q15.2   UniSTS Human Cytogenetic Map 5 q12.3   UniSTS Human Cytogenetic Map 14 q24.1   UniSTS Human Cytogenetic Map 12 q14.1   UniSTS Human Cytogenetic Map 6 p22.3-p22.1   UniSTS Human Cytogenetic Map 7 p11.2   UniSTS Human Cytogenetic Map 6 q15   UniSTS Human Cytogenetic Map 6 q23.3   UniSTS Human Cytogenetic Map 13 q14   UniSTS Human Cytogenetic Map 5 q35.2   UniSTS Human Cytogenetic Map 10 q22.3   UniSTS Human Cytogenetic Map 1 p35   UniSTS Human Cytogenetic Map 3 q12.3   UniSTS Human Cytogenetic Map 19 q13.31   UniSTS Human Cytogenetic Map 8 q23.1   UniSTS Human Cytogenetic Map 6 q27   UniSTS Human Cytogenetic Map 2 q14.3   UniSTS Human Cytogenetic Map X p11   UniSTS Human Cytogenetic Map 11 p15.3   UniSTS Human Cytogenetic Map 20 p12   UniSTS Human Cytogenetic Map 15 q13.1   UniSTS Human Cytogenetic Map X p22.3   UniSTS Human Cytogenetic Map 11 q13.5   UniSTS Human Cytogenetic Map 19 p13.3-p13.2   UniSTS Human Cytogenetic Map 1 p36.11-p34.2   UniSTS Human Cytogenetic Map 4 q22.1-q23   UniSTS Human Cytogenetic Map 7 q22.3   UniSTS Human Cytogenetic Map 9 p22   UniSTS Human Cytogenetic Map 17 q23.3   UniSTS Human Cytogenetic Map 16 q23.2   UniSTS Human Cytogenetic Map 2 p16.1   UniSTS Human Cytogenetic Map 3 q27.1   UniSTS Human Cytogenetic Map 2 p22.3   UniSTS Human Cytogenetic Map X q26.1   UniSTS Human Cytogenetic Map 4 q21.21   UniSTS Human Cytogenetic Map 22 q13.3   UniSTS Human Cytogenetic Map 2 q32.1   UniSTS Human Cytogenetic Map Y p11.32   UniSTS Human Cytogenetic Map 11 p14   UniSTS Human Cytogenetic Map 1 p32.1   UniSTS Human Cytogenetic Map 2 p25.3   UniSTS Human Cytogenetic Map 4 q34.3   UniSTS Human Cytogenetic Map 9 p12   UniSTS Human Cytogenetic Map 3 q13.13   UniSTS Human Cytogenetic Map 13 q34   UniSTS Human Cytogenetic Map 3 p21   UniSTS Human Cytogenetic Map 11 q23.2   UniSTS Human Cytogenetic Map 20 p11.23   UniSTS Human Cytogenetic Map 3 p13   UniSTS Human Cytogenetic Map 4 p13   UniSTS Human Cytogenetic Map 16 q23.1   UniSTS Human Cytogenetic Map 10 p11.23   UniSTS Human Cytogenetic Map 8 p21.1   UniSTS Human Cytogenetic Map 15 q22-q24   UniSTS Human Cytogenetic Map 8 q23   UniSTS Human Cytogenetic Map 16 q12.1   UniSTS Human Cytogenetic Map 14 q13.2   UniSTS Human Cytogenetic Map 18 q12.1   UniSTS Human Cytogenetic Map 5 q31.3   UniSTS Human Cytogenetic Map 11 q14   UniSTS Human Cytogenetic Map 13 q33.1   UniSTS Human Cytogenetic Map 14 q21.2   UniSTS Human Cytogenetic Map 4 q31.3   UniSTS Human Cytogenetic Map 15 q21-q22   UniSTS Human Cytogenetic Map 3 p14.3   UniSTS Human Cytogenetic Map 17 p13.1   UniSTS Human Cytogenetic Map 13 q12.11   UniSTS Human Cytogenetic Map 6 p21.2   UniSTS Human Cytogenetic Map 15 q21.3   UniSTS Human Cytogenetic Map 3 q21.1   UniSTS Human Cytogenetic Map 6 p21.31   UniSTS Human Cytogenetic Map 10 p15.1   UniSTS Human Cytogenetic Map 1 q24.2   UniSTS Human Cytogenetic Map 12 p12   UniSTS Human Cytogenetic Map 7 p22.1   UniSTS Human Cytogenetic Map 11 q24   UniSTS Human Cytogenetic Map 21 q22.13   UniSTS Human Cytogenetic Map 15 q22.1-q22.31   UniSTS Human Cytogenetic Map 15 q22   UniSTS Human Cytogenetic Map X q13   UniSTS Human Cytogenetic Map 1 q31-q41   UniSTS Human Cytogenetic Map 6 p25   UniSTS Human Cytogenetic Map 14 q32.1   UniSTS Human Cytogenetic Map 16 q12-q13   UniSTS Human Cytogenetic Map X q12-q13   UniSTS Human Cytogenetic Map 14 q23   UniSTS Human Cytogenetic Map 12 q11-q12   UniSTS Human Cytogenetic Map 1 q42.1-q43   UniSTS Human Cytogenetic Map 3 q13.33   UniSTS Human Cytogenetic Map 7 q31   UniSTS Human Cytogenetic Map 12 q24   UniSTS Human Cytogenetic Map X p22.11   UniSTS Human Cytogenetic Map 11 q13.4   UniSTS Human Cytogenetic Map 2 p25.1-p24.1   UniSTS Human Cytogenetic Map 8 q24.21   UniSTS Human Cytogenetic Map 12 q13.1   UniSTS Human Cytogenetic Map 12 q22-q23.1   UniSTS Human Cytogenetic Map 11 q12.2   UniSTS Human Cytogenetic Map 1 p13.2   UniSTS Human Cytogenetic Map 5 q31.2-q34   UniSTS Human Cytogenetic Map 11 p15.1   UniSTS Human Cytogenetic Map 6 q24.2   UniSTS Human Cytogenetic Map 22 q   UniSTS Human Cytogenetic Map 12 q13.11-q14.3   UniSTS Human Cytogenetic Map 7 p11   UniSTS Human Cytogenetic Map X p22.12-p22.11   UniSTS Human Cytogenetic Map 7 q11.21   UniSTS Human Cytogenetic Map 20 q11.22-q11.23   UniSTS Human Cytogenetic Map 8 q24.22   UniSTS Human Cytogenetic Map 8 p22-p21.3   UniSTS Human Cytogenetic Map 10 q24   UniSTS Human Cytogenetic Map 1 q21.2-q21.3   UniSTS Human Cytogenetic Map 1 p36.12   UniSTS Human Cytogenetic Map 9 p24.1   UniSTS Human Cytogenetic Map 6 q25.2-q27   UniSTS Human Cytogenetic Map 9 q34   UniSTS Human Cytogenetic Map 5 p13.1   UniSTS Human Cytogenetic Map 8 q11.2   UniSTS Human Cytogenetic Map 3 q28-q29   UniSTS Human Cytogenetic Map 7 p14-p13   UniSTS Human Cytogenetic Map 12 q24.2   UniSTS Human Cytogenetic Map 6 p22.2   UniSTS Human Cytogenetic Map 7 q22-qter   UniSTS Human Cytogenetic Map 12 q24.2-q24.31   UniSTS Human Cytogenetic Map X q13.1   UniSTS Human Cytogenetic Map 6 p25.2   UniSTS Human Cytogenetic Map 1 p21   UniSTS Human Cytogenetic Map 1 q32.2-q41   UniSTS Human Cytogenetic Map 11 q22-q23   UniSTS Human Cytogenetic Map 3 q26.33   UniSTS Human Cytogenetic Map 12 q23-q24.1   UniSTS Human Cytogenetic Map 5 p15.1-p14.3   UniSTS Human Cytogenetic Map 16 p13.11   UniSTS Human Cytogenetic Map 6 q22-q23   UniSTS Human Cytogenetic Map 9 p21   UniSTS Human Cytogenetic Map 6 p12.3   UniSTS Human Cytogenetic Map 3 p12.1   UniSTS Human Cytogenetic Map 9 q21.11   UniSTS Human Cytogenetic Map 17 q24.1   UniSTS Human Cytogenetic Map 10 q11.21   UniSTS Human Cytogenetic Map 14 q21   UniSTS Human Cytogenetic Map 11 p15   UniSTS Human Cytogenetic Map 16 q22   UniSTS Human Cytogenetic Map 15 q11-q13   UniSTS Human Cytogenetic Map 13 q12-q14   UniSTS Human Cytogenetic Map 18 q21.1   UniSTS Human Cytogenetic Map 2 q24   UniSTS Human Cytogenetic Map 12 p13   UniSTS Human Cytogenetic Map 3 q28   UniSTS Human Cytogenetic Map 7 q32.1   UniSTS Human Cytogenetic Map X q22.2   UniSTS Human Cytogenetic Map 7 p12.3   UniSTS Human Cytogenetic Map 7 p15.1   UniSTS Human Cytogenetic Map 2 q37.2   UniSTS Human Cytogenetic Map 18 q22.3   UniSTS Human Cytogenetic Map 14 q32.13   UniSTS Human Cytogenetic Map 14 q22.1   UniSTS Human Cytogenetic Map 16 p13.1   UniSTS Human Cytogenetic Map 7 q31.3   UniSTS Human Cytogenetic Map 20 q13.2-q13.3   UniSTS Human Cytogenetic Map 1 p21.2   UniSTS Human Cytogenetic Map 9 q21.33   UniSTS Human Cytogenetic Map 14 q32.2   UniSTS Human Cytogenetic Map 13 q13.3   UniSTS Human Cytogenetic Map 10 p12.31   UniSTS Human Cytogenetic Map 22 q11.1   UniSTS Human Cytogenetic Map 5 q33.2   UniSTS Human Cytogenetic Map 13 q32.2   UniSTS Human Cytogenetic Map 14 q23.1   UniSTS Human Cytogenetic Map 8 q21.2   UniSTS Human Cytogenetic Map 2 q24.1   UniSTS Human Cytogenetic Map 10 q26.13   UniSTS Human Cytogenetic Map 2 q23.3   UniSTS Human Cytogenetic Map 19 p13.1   UniSTS Human Cytogenetic Map 15 q14-q15   UniSTS Human Cytogenetic Map 1 q42.13   UniSTS Human Cytogenetic Map 14 q31   UniSTS Human Cytogenetic Map 7 p21.1   UniSTS Human Cytogenetic Map 8 p12-p11   UniSTS Human Cytogenetic Map 18 p11.2   UniSTS Human Cytogenetic Map 7 p11.1   UniSTS Human Cytogenetic Map 1 q31-q32   UniSTS Human Cytogenetic Map 2 q12   UniSTS Human Cytogenetic Map 3 p21.32   UniSTS Human Cytogenetic Map 2 p24.2   UniSTS Human Cytogenetic Map 2 q33-q34   UniSTS Human Cytogenetic Map 6 q24.1   UniSTS Human Cytogenetic Map 4 q22.1   UniSTS Human Cytogenetic Map 15 q13.3   UniSTS Human Cytogenetic Map 10 q26.11   UniSTS Human Cytogenetic Map 7 p15.3   UniSTS Human Cytogenetic Map 10 q23.33   UniSTS Human Cytogenetic Map 12 p12.1   UniSTS Human Cytogenetic Map 7 p13-p12   UniSTS Human Cytogenetic Map X q25   UniSTS Human Cytogenetic Map 17 q11-q21   UniSTS Human Cytogenetic Map 12 q23   UniSTS Human Cytogenetic Map 6 p24-p22.3   UniSTS Human Cytogenetic Map 14 q23.2   UniSTS Human Cytogenetic Map 7 q31.1-q31.2   UniSTS Human Cytogenetic Map 8 q22.2   UniSTS Human Cytogenetic Map 15 q21.2   UniSTS Human Cytogenetic Map 3 p26.1-p25.1   UniSTS Human Cytogenetic Map 5 q35   UniSTS Human Cytogenetic Map 3 q13.2   UniSTS Human Cytogenetic Map 4 p15.2   UniSTS Human Cytogenetic Map 6 q16.3   UniSTS Human Cytogenetic Map 17 q24-q25   UniSTS Human Cytogenetic Map X q12   UniSTS Human Cytogenetic Map X q27.1   UniSTS Human Cytogenetic Map 8 q12.3   UniSTS Human Cytogenetic Map 5 q21.2   UniSTS Human Cytogenetic Map 5 q15   UniSTS Human Cytogenetic Map 5 q35.1   UniSTS Human Cytogenetic Map 4 q13.3   UniSTS Human Cytogenetic Map 4 q35.2   UniSTS Human Cytogenetic Map 3 p26.1   UniSTS Human Cytogenetic Map 3 p11.1   UniSTS Human Cytogenetic Map 17 q21.2   UniSTS Human Cytogenetic Map 2 q21.2   UniSTS Human Cytogenetic Map 19 p13.13   UniSTS Human Cytogenetic Map 18 q12.3   UniSTS Human Cytogenetic Map 18 p11.3   UniSTS Human Cytogenetic Map 17 q11.1   UniSTS Human Cytogenetic Map 15 q25.1   UniSTS Human Cytogenetic Map 13 q12.3   UniSTS Human Cytogenetic Map 12 q23.2   UniSTS Human Cytogenetic Map 12 q12-q13   UniSTS Human Cytogenetic Map 12 q14   UniSTS Human Cytogenetic Map 5 q33.1   UniSTS Human Cytogenetic Map 2 q32-q34   UniSTS Human Cytogenetic Map 16 q22.3   UniSTS Human Cytogenetic Map 2 p15-p13   UniSTS Human Cytogenetic Map X p11.4   UniSTS Human Cytogenetic Map 19 q13.33-q13.41   UniSTS Human Cytogenetic Map 20 p11   UniSTS Human Cytogenetic Map 6 q23-q24   UniSTS Human Cytogenetic Map 2 p12   UniSTS Human Cytogenetic Map 2 p13   UniSTS Human Cytogenetic Map 13 q11-q12   UniSTS Human Cytogenetic Map 6 p12.3-p11.2   UniSTS Human Cytogenetic Map 6 q16.1-q16.3   UniSTS Human Cytogenetic Map 22 q11   UniSTS Human Cytogenetic Map 7 q31.2   UniSTS Human Cytogenetic Map 10 q21.3   UniSTS Human Cytogenetic Map 3 q25.2   UniSTS Human Cytogenetic Map 3 p21.1-p14.3   UniSTS Human Cytogenetic Map 6 p12.1   UniSTS Human Cytogenetic Map 3 q23-q24   UniSTS Human Cytogenetic Map 3 q12   UniSTS Human Cytogenetic Map 7 q11.1   UniSTS Human Cytogenetic Map 3 q22.3   UniSTS Human Cytogenetic Map 7 q21.3   UniSTS Human Cytogenetic Map 4 q31.1   UniSTS Human Cytogenetic Map 22 q12-q13   UniSTS Human Cytogenetic Map 4 q23   UniSTS Human Cytogenetic Map X p22.12   UniSTS Human Cytogenetic Map 6 q16.1   UniSTS Human Cytogenetic Map 13 q14.13   UniSTS Human Cytogenetic Map 18 q21.3   UniSTS Human Cytogenetic Map 9 q33.2   UniSTS Human Cytogenetic Map 11 q21   UniSTS Human Cytogenetic Map 8 q12   UniSTS Human Cytogenetic Map 4 q28-q32   UniSTS Human Cytogenetic Map 17 q24.3   UniSTS Human Cytogenetic Map 6 p23   UniSTS Human Cytogenetic Map 8 p11   UniSTS Human Cytogenetic Map 5 q34   UniSTS Human Cytogenetic Map 1 q24.3   UniSTS Human Cytogenetic Map 9 q33.1   UniSTS Human Cytogenetic Map 1 q23.3   UniSTS Human Cytogenetic Map 2 p16.2   UniSTS Human Cytogenetic Map 9 q22.31   UniSTS Human Cytogenetic Map 9 p24.3   UniSTS Human Cytogenetic Map 7 q35   UniSTS Human Cytogenetic Map 1 p36.2   UniSTS Human Cytogenetic Map 11 q22.3   UniSTS Human Cytogenetic Map 16 p12   UniSTS Human Cytogenetic Map 1 q22-q23   UniSTS Human Cytogenetic Map 13 q22.1   UniSTS Human Cytogenetic Map 2 q12.2   UniSTS Human Cytogenetic Map 8 p12   UniSTS Human Cytogenetic Map 4 q21   UniSTS Human Cytogenetic Map 13 q12.2   UniSTS Human Cytogenetic Map 9 q31-q33   UniSTS Human Cytogenetic Map 6 p24.1   UniSTS Human Cytogenetic Map 1 q23   UniSTS Human Cytogenetic Map 11 q12-q13   UniSTS Human Cytogenetic Map 11 q13.3   UniSTS Human Cytogenetic Map 11 q24.2   UniSTS Human Cytogenetic Map 11 q12.1   UniSTS Human Cytogenetic Map 3 p26   UniSTS Human Cytogenetic Map 5 q13   UniSTS Human Cytogenetic Map 8 p21   UniSTS Human Cytogenetic Map 19 q13.1-q13.2   UniSTS Human Cytogenetic Map 1 p33-p32   UniSTS Human Cytogenetic Map 7 q36.2   UniSTS Human Cytogenetic Map 4 q32.3   UniSTS Human Cytogenetic Map 16 p13.2   UniSTS Human Cytogenetic Map 14 q32   UniSTS Human Cytogenetic Map 10 q11.23   UniSTS Human Cytogenetic Map 10 q26.1   UniSTS Human Cytogenetic Map 9 q32-q33.3   UniSTS Human Cytogenetic Map 9 q22.1-q22.2   UniSTS Human Cytogenetic Map 3 q26.1-q26.2   UniSTS Human Cytogenetic Map 5 q31-q34   UniSTS Human Cytogenetic Map 9 q33-q34   UniSTS Human Cytogenetic Map 5 q11.2-q13.2   UniSTS Human Cytogenetic Map 13 q32   UniSTS Human Cytogenetic Map 9 q22.32   UniSTS Human Cytogenetic Map 1 p36.3   UniSTS Human Cytogenetic Map 1 p36.3-p36.2   UniSTS Human Cytogenetic Map 4 q28.1   UniSTS Human Cytogenetic Map 5 q22   UniSTS Human Cytogenetic Map 12 p11.21   UniSTS Human Cytogenetic Map X q13.3   UniSTS Human Cytogenetic Map 9 q31.3   UniSTS Human Cytogenetic Map 3 p26.3   UniSTS Human Cytogenetic Map 2 q11.1   UniSTS Human Cytogenetic Map 21 q11.2   UniSTS Human Cytogenetic Map 18 q21.32   UniSTS Human Cytogenetic Map 15 q26.2   UniSTS Human Cytogenetic Map 12 q24.23   UniSTS Human Cytogenetic Map 10 q25.3   UniSTS Human Cytogenetic Map 20 q11.23   UniSTS Human Cytogenetic Map 20 p12.1   UniSTS Human Cytogenetic Map 2 q31.1-q31.2   UniSTS Human Cytogenetic Map X p22.31   UniSTS Human Cytogenetic Map X p21.3   UniSTS Human Cytogenetic Map 5 q33.3   UniSTS Human Cytogenetic Map 4 q28.2   UniSTS Human Cytogenetic Map 3 p14.2   UniSTS Human Cytogenetic Map 3 q24   UniSTS Human Cytogenetic Map 2 q13   UniSTS Human Cytogenetic Map 20 q13.2   UniSTS Human Cytogenetic Map 14 q11.2-q12   UniSTS Human Cytogenetic Map 3 p24   UniSTS Human Cytogenetic Map 12 q23.3   UniSTS Human Cytogenetic Map 11 q24.3   UniSTS Human Cytogenetic Map 11 q14.3   UniSTS Human Cytogenetic Map 10 q25.2   UniSTS Human Cytogenetic Map 3 q25.1   UniSTS Human Cytogenetic Map 8 q13   UniSTS Human Cytogenetic Map 1 p22.2   UniSTS Human Cytogenetic Map 3 p22.3   UniSTS Human Cytogenetic Map 18 q11.1   UniSTS Human Cytogenetic Map 8 q23.3   UniSTS Human Cytogenetic Map 15 q24   UniSTS Human Cytogenetic Map 11 cen-q12   UniSTS Human Cytogenetic Map 11 q25   UniSTS Human Cytogenetic Map 3 p22.2   UniSTS Human Cytogenetic Map X p21.1   UniSTS Human Cytogenetic Map 7 q36   UniSTS Human Cytogenetic Map 7 p14.3   UniSTS Human Cytogenetic Map 12 q21   UniSTS Human Cytogenetic Map 7 p15   UniSTS Human Cytogenetic Map 7 q22-q31   UniSTS Human Cytogenetic Map 11 q22   UniSTS Human Cytogenetic Map 5 p15.3   UniSTS Human Cytogenetic Map 20 q13.3-qter   UniSTS Human Cytogenetic Map 1 p35-p34   UniSTS Human Cytogenetic Map 4 p13-p12   UniSTS Human Cytogenetic Map 10 q21-q22   UniSTS Human Cytogenetic Map 4 q22   UniSTS Human Cytogenetic Map 7 p13-p11.1   UniSTS Human Cytogenetic Map 9 q31-q34   UniSTS Human Cytogenetic Map 7 q21.1-q22   UniSTS Human Cytogenetic Map 15 q26.1   UniSTS Human Cytogenetic Map 3 q13.13-q13.2   UniSTS Human Cytogenetic Map X p22.13   UniSTS Human Cytogenetic Map 13 q12.12   UniSTS Human Cytogenetic Map 13 q14.2   UniSTS Human Cytogenetic Map 12 q   UniSTS Human Cytogenetic Map 1 p   UniSTS Human Cytogenetic Map 16 p   UniSTS Human Cytogenetic Map 15 q   UniSTS Human Cytogenetic Map 7 q   UniSTS Human Cytogenetic Map 2 q   UniSTS Human Cytogenetic Map 5 q13.1   UniSTS Human Cytogenetic Map 11 p14.1   UniSTS Human Cytogenetic Map 4 q32   UniSTS Human Cytogenetic Map 2 p22   UniSTS Human Cytogenetic Map 5 q14.3   UniSTS Human Cytogenetic Map 10 p12.1   UniSTS Human Cytogenetic Map 5 q23.2   UniSTS Human Cytogenetic Map 2 p24.1   UniSTS Human Cytogenetic Map 16 q22.1-q22.2   UniSTS Human Cytogenetic Map 8 q24.13   UniSTS Human Cytogenetic Map 12 p13.32   UniSTS Human Cytogenetic Map 9 p21.1   UniSTS QTLs in Region (Human Genome Assembly GRCh37) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 1559115 SCL20_H Serum cholesterol level QTL 20 (human) 3.22 .001213 Lipid level LDL cholesterol 11 100313159 126313159 Human 2293387 PRSTS275_H Prostate tumor susceptibility QTL 275 (human) Prostate tumor susceptibility 11 102287419 128287419 Human 1298500 RA19_H Rheumatoid arthritis QTL 19 (human) .0258 Joint/bone inflammation rheumatoid arthritis 11 104697838 130697838 Human 2289605 BW474_H Body weight QTL 474 (human) 1.4 Body fat amount abdominal 11 107828366 133828366 Human 2314734 GLUCO83_H Glucose level QTL 83 (human) .8 .041 Glucose level non-insulin dependent 11 107828366 133828366 Human 1559358 SCL91_H Serum cholesterol level QTL 91 (human) 2.03 .001 Lipid level triglyceride 11 109297904 134937540 Human 1559127 SCL54_H Serum cholesterol level QTL 54 (human) 1.93 Lipid level triglyceride 11 110626746 134937540 Human 1643285 SADIPOQ1_H Serum adiponectin level QTL 1 (human) 2.33 Hormone level serum adiponectin level 11 110626746 134937540 Human 1643503 BW290_H Body Weight QTL 290 (human) 2.1 Body weight BMI 11 110626746 134937540 Human 2292836 MYI33_H Myocardial infarction susceptibility QTL 33 (human) Myocardial infarction susceptibility early-onset 11 110626746 134937540 Human 2292856 MYI32_H Myocardial infarction susceptibility QTL 32 (human) Myocardial infarction susceptibility early-onset 11 110626746 134937540 Human 1298513 BP22_H Blood pressure QTL 22 (human) .004 Blood pressure hypertension susceptibility 11 113080426 134937540 Human 2289548 BW430_H Body weight QTL 430 (human) Body weight BMI 11 113080426 134937540 Human 1643437 SLIPL1_H Serum lipid level QTL 1 (human) 2.66 .00023 Lipid level 11 115624149 134937540 Human 1643567 GLUCO29_H Glucose level QTL 29 (human) .71 .035 Glucose level non-insulin-dependent 11 115624149 134937540 Human 2315060 GLUCO129_H Glucose level QTL 129 (human) 1.47 .0046 Glucose level 11 117697760 132586399 Human 2315062 GLUCO130_H Glucose level QTL 130 (human) 2.32 .0005 Glucose level 11 117697760 132586399 Human 2293444 PRSTS276_H Prostate tumor susceptibility QTL 276 (human) Prostate tumor susceptibility 11 118538165 134937540 Human 2314738 GLUCO84_H Glucose level QTL 84 (human) .89 .005 Glucose level non-insulin dependent 11 118605749 134937540 Human 2315059 GLUCO138_H Glucose level QTL 138 (human) 1.155 Glucose level 11 120828264 128624205 Human 1643548 SADIPOQ10_H Serum adiponectin level QTL 10 (human) 4.2 Hormone level adiponectin level 11 120828264 134937540 Human 2314991 INSUL34_H Insulin level QTL 34 (human) 1.8 Insulin level 11 123626627 128624205 Human Sequence Nucleotide Sequences Nucleotide RefSeqs NG_030049 (Get FASTA) Search GEO for Microarray Profiles   NM_001114121 (Get FASTA) Search GEO for Microarray Profiles   NM_001114122 (Get FASTA) Search GEO for Microarray Profiles   NM_001244846 (Get FASTA) Search GEO for Microarray Profiles   NM_001274 (Get FASTA) Search GEO for Microarray Profiles   NR_045204 (Get FASTA) Search GEO for Microarray Profiles   NR_045205 (Get FASTA) Search GEO for Microarray Profiles GenBank Nucleotide AA224205 (Get FASTA) Search GEO for Microarray Profiles   AB032387 (Get FASTA) Search GEO for Microarray Profiles   AB451222 (Get FASTA) Search GEO for Microarray Profiles   AB451345 (Get FASTA) Search GEO for Microarray Profiles   ABBA01031239 (Get FASTA) Search GEO for Microarray Profiles   AF016582 (Get FASTA) Search GEO for Microarray Profiles   AF032874 (Get FASTA) Search GEO for Microarray Profiles   AF527555 (Get FASTA) Search GEO for Microarray Profiles   AI750792 (Get FASTA) Search GEO for Microarray Profiles   AK292549 (Get FASTA) Search GEO for Microarray Profiles   AK293143 (Get FASTA) Search GEO for Microarray Profiles   AK299783 (Get FASTA) Search GEO for Microarray Profiles   AK300082 (Get FASTA) Search GEO for Microarray Profiles   AMYH01004108 (Get FASTA) Search GEO for Microarray Profiles   AP001132 (Get FASTA) Search GEO for Microarray Profiles   AW149126 (Get FASTA) Search GEO for Microarray Profiles   AY304548 (Get FASTA) Search GEO for Microarray Profiles   BC004202 (Get FASTA) Search GEO for Microarray Profiles   BC017575 (Get FASTA) Search GEO for Microarray Profiles   BG191840 (Get FASTA) Search GEO for Microarray Profiles   BG216281 (Get FASTA) Search GEO for Microarray Profiles   BG218896 (Get FASTA) Search GEO for Microarray Profiles   BG468734 (Get FASTA) Search GEO for Microarray Profiles   BM455102 (Get FASTA) Search GEO for Microarray Profiles   BP203333 (Get FASTA) Search GEO for Microarray Profiles   BP207812 (Get FASTA) Search GEO for Microarray Profiles   BX114781 (Get FASTA) Search GEO for Microarray Profiles   BX419129 (Get FASTA) Search GEO for Microarray Profiles   BX506561 (Get FASTA) Search GEO for Microarray Profiles   CA441277 (Get FASTA) Search GEO for Microarray Profiles   CA868104 (Get FASTA) Search GEO for Microarray Profiles   CH471065 (Get FASTA) Search GEO for Microarray Profiles   DA567616 (Get FASTA) Search GEO for Microarray Profiles   JF289264 (Get FASTA) Search GEO for Microarray Profiles Reference Sequences RefSeq Acc Id: NM_001114121 RefSeq Status: REVIEWED Type: CODING Protein Acc Id: NP_001107593 Peptide Label: isoform 1 Position: Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI RefSeq Acc Id: NM_001114122 RefSeq Status: REVIEWED Type: CODING Protein Acc Id: NP_001107594 Peptide Label: isoform 1 Position: Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI RefSeq Acc Id: NM_001274 RefSeq Status: REVIEWED Type: CODING Protein Acc Id: NP_001265 Peptide Label: isoform 1 Position: Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI Human Genome Assembly Build 36 11 125,001,547 - 125,030,847 + NCBI Archive RefSeq Acc Id: NM_001244846 RefSeq Status: REVIEWED Type: CODING Protein Acc Id: NP_001231775 Peptide Label: isoform 2 Position: Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI RefSeq Acc Id: NR_045204 RefSeq Status: REVIEWED Type: NON-CODING Position: Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI RefSeq Acc Id: NR_045205 RefSeq Status: REVIEWED Type: NON-CODING Position: Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 125,361,632 - 125,412,754 + NCBI Human Genome Assembly HuRef 11 121,436,397 - 121,487,529 + NCBI Human Genome Assembly GRCh37 11 125,495,031 - 125,546,150 + NCBI Protein Sequences Protein RefSeqs NP_001107593 (Get FASTA)   NP_001107594 (Get FASTA)   NP_001231775 (Get FASTA)   NP_001265 (Get FASTA) GenBank Protein AAB88852 (Get FASTA)   AAC51736 (Get FASTA)   AAH04202 (Get FASTA)   AAH17575 (Get FASTA)   AAM78553 (Get FASTA)   AAQ76038 (Get FASTA)   ABM83833 (Get FASTA)   ABM87141 (Get FASTA)   AEB71796 (Get FASTA)   BAA84577 (Get FASTA)   BAF85238 (Get FASTA)   BAG56691 (Get FASTA)   BAG61665 (Get FASTA)   BAG61885 (Get FASTA)   BAG70036 (Get FASTA)   BAG70159 (Get FASTA)   EAW67644 (Get FASTA)   O14757 (Get FASTA) Promoters RGD ID: 6788632 Promoter ID: HG_KWN:14519 Type: CpG-Island SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4 Transcripts: NM_001114121,   NM_001114122,   NM_001274,   UC001QCH.2,   UC001QCI.1,   UC009ZBP.1,   UC009ZBQ.1 Position: Map Chr Position Strand Source Human Genome Assembly Build 36 11 125,000,616 - 125,001,116 + MPROMDB RGD ID: 6852634 Promoter ID: EP74129 Type: initiation region Name: HS_CHEK1 Description: CHK1 checkpoint homolog (S. pombe). SO ACC ID: SO:0000170 Source: EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/) Experiment Methods: Mammalian gene collection (MGC) full-length cDNA cloning Position: Map Chr Position Strand Source Human Genome Assembly Build 36 11 125,001,094 - 125,001,154   EPD Additional Information External Database Links Database Acc Id Source(s) COSMIC CHEK1 COSMIC Ensembl Genes ENSG00000149554 ENTREZGENE Ensembl Protein ENSP00000435371 ENTREZGENE Ensembl Transcript ENST00000534070 ENTREZGENE Entrez Gene 1111 ENTREZGENE Germonline ENSG00000149554 HGNC ID 1925 ENTREZGENE HomoloGene Group ID 975 ENTREZGENE HPRD ID 04356 ENTREZGENE InterPro Kinase-like_dom UniProtKB/Swiss-Prot   Prot_kinase_cat_dom UniProtKB/Swiss-Prot   Protein_kinase_ATP_BS UniProtKB/Swiss-Prot   Ser/Thr_kinase_AS UniProtKB/Swiss-Prot   Ser/Thr_kinase_dom UniProtKB/Swiss-Prot IPI IPI00023664 UniProtKB/Swiss-Prot   IPI00909845 UniProtKB/TrEMBL   IPI00973081 UniProtKB/Swiss-Prot   IPI00978454 UniProtKB/TrEMBL   IPI00981751 UniProtKB/TrEMBL   IPI00983124 UniProtKB/TrEMBL   IPI00984333 UniProtKB/TrEMBL   IPI01008883 UniProtKB/TrEMBL KEGG Report hsa:1111 ENTREZGENE, UniProtKB/Swiss-Prot OMIM 603078 OMIM Pfam Pkinase UniProtKB/Swiss-Prot PharmGKB CHEK1 RGD, PharmGKB PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot   PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot   PROTEIN_KINASE_ST UniProtKB/Swiss-Prot SMART S_TKc UniProtKB/Swiss-Prot Superfamily-SCOP Kinase_like UniProtKB/Swiss-Prot UniGene Hs.24529 ENTREZGENE   Hs.595920 ENTREZGENE UniProt B4DT73_HUMAN UniProtKB/TrEMBL   CHK1_HUMAN UniProtKB/Swiss-Prot   E7EPP6_HUMAN UniProtKB/TrEMBL   E9PJI4_HUMAN UniProtKB/TrEMBL   E9PKQ3_HUMAN UniProtKB/TrEMBL   E9PM65_HUMAN UniProtKB/TrEMBL   E9PPA5_HUMAN UniProtKB/TrEMBL   E9PQW7_HUMAN UniProtKB/TrEMBL   E9PRU7_HUMAN UniProtKB/TrEMBL   J3KN87_HUMAN UniProtKB/TrEMBL Nomenclature History Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status 2011-11-22 CHEK1  checkpoint kinase 1  CHEK1  CHK1 checkpoint homolog (S. pombe)  Symbol and/or name change 39860 APPROVED 2011-10-11 CHEK1  CHK1 checkpoint homolog (S. pombe)  CHEK1  CHK1 checkpoint homolog (S. pombe)  Symbol and/or name change 39860 APPROVED

More on CHEK1 Entrez Gene Ensembl Gene Genome Browser: (hg18) (hg19) HGNC Report NCBI Map Viewer Vista Vista + UCSC RGD Object Information RGD ID: 732292 Created: 2004-01-12 Species: Homo sapiens Last Modified: 2013-04-16 Status: ACTIVE