Gene: ACTB (actin beta) Homo sapiens
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Symbol: ACTB
Name: actin beta
Description: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: actin, beta; actin, cytoplasmic 1; beta cytoskeletal actin; BRWS1; OTTHUMP00000024886; PS1TP5-binding protein 1; PS1TP5BP1
Orthologs:
Mus musculus (house mouse) : Actb (actin, beta)  MGI  AGR
Rattus norvegicus (Norway rat) : Actb (actin, beta)  AGR
Chinchilla lanigera (long-tailed chinchilla) : Actb (actin beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTB (actin beta)
Canis lupus familiaris (dog) : ACTB (actin beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actb (actin beta)
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Related Pseudogenes: ACTBP1   ACTBP10   ACTBP11   ACTBP12   ACTBP13   ACTBP2   ACTBP3   ACTBP4   ACTBP6   ACTBP7   ACTBP8   ACTBP9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3875,527,148 - 5,530,601 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3775,566,779 - 5,570,232 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,533,312 - 5,536,747 (-)NCBINCBI36hg18NCBI36
Build 3475,340,026 - 5,343,462NCBI
Celera75,526,560 - 5,530,009 (-)NCBI
Cytogenetic Map7p22.1NCBI
HuRef75,479,343 - 5,482,774 (-)NCBIHuRef
CHM1_175,566,362 - 5,569,815 (-)NCBICHM1_1
CRA_TCAGchr7v275,613,124 - 5,616,577 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
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miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on ACTB
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735801
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2017-12-26
Status: ACTIVE