Gene: BAG1 (BCL2-associated athanogene)  Homo sapiens

Symbol: BAG1
Name: BCL2-associated athanogene
Description: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BAG family molecular chaperone regulator 1; BAG-1; BAG-1; Bcl-2 associating athanogene-1 protein; bcl-2-associated athanogene 1; Bcl-2-binding protein; glucocortoid receptor-associated protein RAP46; HAP; OTTHUMP00000021198; OTTHUMP00000021199; RAP46; receptor-associated protein, 46-KD
Orthologs: Mus musculus : Bag1 (BCL2-associated athanogene 1)  MGI
Rattus norvegicus : Bag1 (BCL2-associated athanogene)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1933,221,708 - 33,234,001-NCBI
Human Genome Assembly HuRef933,209,370 - 33,221,664-NCBI
Human Genome Assembly GRCh37933,252,469 - 33,264,759-NCBI
Human Genome Assembly Build 36933,242,469 - 33,254,761-NCBI
Human Cytogenetic Map9p12 NCBI
Human Genome Assembly933,245,025 - 33,254,737 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on BAG1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1313091
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-05-14
Status: ACTIVE