Gene: LDHA (lactate dehydrogenase A)  Homo sapiens

Symbol: LDHA
Name: lactate dehydrogenase A
Description: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cell proliferation-inducing gene 19 protein; GSD11; L-lactate dehydrogenase A chain; lactate dehydrogenase M; LDH muscle subunit; LDH-A; LDH-M; LDH-M; LDH1; LDHM; OTTHUMP00000165205; OTTHUMP00000165206; OTTHUMP00000165207; OTTHUMP00000236636; OTTHUMP00000236642; OTTHUMP00000236646; OTTHUMP00000236647; PIG19; proliferation-inducing gene 19; renal carcinoma antigen NY-REN-59
Orthologs: Mus musculus : Ldha (lactate dehydrogenase A)  MGI
Rattus norvegicus : Ldha (lactate dehydrogenase A)
Related Pseudogenes: LDHAP1   LDHAP2   LDHAP3   LDHAP4   LDHAP5   LDHAP7  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11118,340,126 - 18,354,011+NCBI
Human Genome Assembly HuRef1118,101,143 - 18,114,981+NCBI
Human Genome Assembly GRCh371118,415,936 - 18,429,765+NCBI
Human Genome Assembly Build 361118,372,687 - 18,385,969+NCBI
Human Cytogenetic Map11p15.4 NCBI
Human Genome Assembly1118,372,686 - 18,385,969 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on LDHA
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736025
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-04-16
Status: ACTIVE