TLR4 (toll like receptor 4) - Rat Genome Database

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Gene: TLR4 (toll like receptor 4) Homo sapiens
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Symbol: TLR4
Name: toll like receptor 4
RGD ID: 737013
HGNC Page HGNC:11850
Description: Enables several functions, including lipopolysaccharide binding activity; lipopolysaccharide immune receptor activity; and protein heterodimerization activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of defense response; and response to lipopolysaccharide. Acts upstream of or within lipopolysaccharide-mediated signaling pathway. Located in several cellular components, including external side of plasma membrane; perinuclear region of cytoplasm; and phagocytic cup. Part of lipopolysaccharide receptor complex. Is active in endosome membrane and plasma membrane. Implicated in several diseases, including allergic contact dermatitis (multiple); artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Biomarker of several diseases, including autoimmune disease (multiple); eye disease (multiple); liver disease (multiple); middle ear disease (multiple); and tuberculosis (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ARMD10; CD284; homolog of Drosophila toll; hToll; TLR-4; TOLL; toll-like receptor 4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is relevant for COVID-19 treatment.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389117,704,403 - 117,724,735 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9117,704,175 - 117,724,735 (+)EnsemblGRCh38hg38GRCh38
GRCh379120,466,681 - 120,487,013 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369119,506,431 - 119,519,589 (+)NCBINCBI36Build 36hg18NCBI36
Build 349117,546,137 - 117,556,781NCBI
Celera991,114,228 - 91,127,535 (+)NCBICelera
Cytogenetic Map9q33.1NCBI
HuRef990,084,535 - 90,097,850 (+)NCBIHuRef
CHM1_19120,614,005 - 120,627,323 (+)NCBICHM1_1
T2T-CHM13v2.09129,898,286 - 129,918,621 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acanthamoeba Keratitis  (ISO)
acne  (IAGP)
Acne Conglobata  (IAGP)
Acute Coronary Syndrome  (EXP)
acute kidney failure  (EXP,ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
acute necrotizing pancreatitis  (ISO)
acute pancreatitis  (ISO)
Acute Tubulointerstitial Nephritis  (ISO)
Acute-On-Chronic Liver Failure  (ISO)
Alcoholic Fatty Liver  (ISO)
allergic conjunctivitis  (IEP,ISO)
allergic contact dermatitis  (IDA,ISO)
allergic rhinitis  (IAGP,IDA,IEP)
Alzheimer's disease  (IAGP)
ankylosing spondylitis  (IEP)
anogenital venereal wart  (IEP)
anterior uveitis  (IDA,ISO)
arteriosclerosis  (IAGP)
arthritis  (IAGP)
asthma  (IAGP,IEP,ISO)
atherosclerosis  (EXP)
atopic dermatitis  (IAGP,IEP)
Bacteremia  (IAGP)
Bacterial Keratitis  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (IAGP,IEP)
Brain Injuries  (EXP,ISO)
brain ischemia  (IAGP)
breast cancer  (IAGP)
Bronchial Hyperreactivity  (ISO)
carcinoma  (EXP)
carotid artery disease  (IAGP)
carotid stenosis  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholesteatoma  (IEP)
cholesteatoma of middle ear  (IEP)
Chronic Hepatitis B  (IEP)
Chronic Hepatitis C  (IAGP,IEP)
Chronic Intermittent Hypoxia  (ISO)
chronic obstructive pulmonary disease  (IAGP,IEP)
Chronic Pain  (IDA)
Chronic Periodontitis  (IEP)
colitis  (ISO)
Colorectal Neoplasms  (EXP)
contact dermatitis  (EXP)
coronary artery disease  (EXP,IAGP)
COVID-19  (IAGP)
Crohn's disease  (EXP)
cutaneous leishmaniasis  (IEP)
cystic echinococcosis  (IEP)
cystic fibrosis  (IEP,ISO)
dermatomyositis  (IEP)
diabetes mellitus  (IAGP,IEP)
Diabetic Foot  (IAGP)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (EXP,IAGP,ISO)
diabetic retinopathy  (IAGP)
dry eye syndrome  (IEP,ISO)
Dysbiosis  (EXP)
end stage renal disease  (IEP)
Endotoxemia  (ISO)
Entamoebiasis  (ISO)
Eosinophilia  (EXP)
Escherichia Coli Meningitis  (ISO)
esophagus adenocarcinoma  (EXP)
essential hypertension  (EXP)
eumycotic mycetoma  (ISO)
exfoliation syndrome  (IAGP)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Autoimmune Uveitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (EXP,ISO)
extrahepatic cholestasis  (EXP)
eye disease  (IEP)
familial mediterranean fever  (IAGP)
Fibrosis  (EXP)
Fungal Eye Infections  (ISO)
Fungal Keratitis  (ISO)
genetic disease  (IAGP)
glomerulonephritis  (ISO)
Hearing Loss  (EXP,IAGP)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (EXP,IAGP,IEP)
hepatorenal syndrome  (ISO)
Herpes Simplex Encephalitis  (ISO)
herpes simplex virus keratitis  (IEP,ISO)
Hyperalgesia  (IDA,ISO)
hypertension  (EXP)
ileitis  (ISO)
Inflammation  (EXP)
Insulin Resistance  (IEP,ISO)
invasive aspergillosis  (IAGP)
Kawasaki disease  (IEP)
keratitis  (IAGP,IEP,ISO)
kidney failure  (EXP,ISO)
Kidney Reperfusion Injury  (ISO)
learning disability  (EXP)
leptospirosis  (ISO)
liver cirrhosis  (IEP,ISO)
Liver Injury  (ISO)
Liver Reperfusion Injury  (ISO)
low tension glaucoma  (IAGP)
lung adenocarcinoma  (IAGP)
lung disease  (ISO)
Lung Injury  (EXP)
Lung Neoplasms  (EXP)
Lung Reperfusion Injury  (ISO)
Lymphatic Metastasis  (IEP)
macular degeneration  (EXP,IAGP)
mastitis  (ISO)
mastoiditis  (IEP)
melanoma  (EXP,IAGP)
membranoproliferative glomerulonephritis  (ISO)
meningococcal meningitis  (IAGP)
metabolic dysfunction-associated steatotic liver disease  (ISO)
multiple sclerosis  (IEP)
myocardial infarction  (IAGP)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (IEP)
Neoplasm Invasiveness  (EXP)
Neoplasm Metastasis  (EXP)
Neuralgia  (ISO)
obesity  (ISO)
Ocular Onchocerciasis  (ISO)
Optic Nerve Injuries  (ISO)
Oral Lichen Planus  (IEP)
otitis media  (IEP,ISO)
Otitis Media with Effusion  (ISO)
Ovarian Neoplasms  (EXP)
Pain  (ISO)
Painful Neuropathy  (ISO)
pancreatitis  (ISO)
perinatal necrotizing enterocolitis  (EXP,ISO)
periodontitis  (IAGP)
Plaque, Atherosclerotic  (IEP)
pleural tuberculosis  (IEP)
Pneumococcal Meningitis  (ISO)
pneumonia  (EXP,ISO)
pre-eclampsia  (IEP)
primary open angle glaucoma  (IAGP)
Prostatic Neoplasms  (EXP)
Pseudomonas Aeruginosa Keratitis  (IEP,ISO)
psoriasis  (IEP)
pulmonary edema  (ISO)
pulmonary emphysema  (ISO,ISS)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (IAGP,IEP)
pulpitis  (ISO)
renal fibrosis  (ISO)
Reperfusion Injury  (EXP,ISO)
respiratory allergy  (EXP,IAGP)
Respiratory Sounds  (IAGP)
respiratory syncytial virus infectious disease  (IAGP,ISO)
Retina Reperfusion Injury  (ISO)
Rhinosinusitis  (IEP)
sciatic neuropathy  (ISO)
Seasonal Allergic Rhinitis  (IAGP)
Sepsis  (EXP,ISO)
severe COVID-19  (IAGP)
sinusitis  (IEP,ISO)
Spinal Cord Injuries  (ISO)
Spinal Cord Reperfusion Injury  (ISO)
sporotrichosis  (ISO)
squamous cell carcinoma  (IAGP)
Stable Angina  (EXP)
steatotic liver disease  (EXP)
Stroke  (IEP)
Subarachnoid Hemorrhage  (ISO)
suppurative otitis media  (IEP)
systemic lupus erythematosus  (ISO)
temporal arteritis  (IAGP)
Transplant Rejection  (ISO)
tuberculosis  (ISO)
tympanosclerosis  (IAGP)
type 1 diabetes mellitus  (IEP,ISO)
type 2 diabetes mellitus  (IAGP,IEP,ISO)
urinary bladder cancer  (ISO)
urinary tract infection  (IAGP)
uveitis  (ISO)
Ventricular Dysfunction, Left  (EXP)
Viral Bronchiolitis  (IEP)
viral meningitis  (ISO)
vitiligo  (IAGP)
Wallerian Degeneration  (ISO)
Weight Loss  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-epicatechin-3-O-gallate  (EXP)
(+)-pilocarpine  (ISO)
(-)-demecolcine  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(24S)-24-hydroxycholesterol  (EXP)
(25R)-cholest-5-ene-3beta,26-diol  (EXP)
(S)-nicotine  (EXP,ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (ISO)
1,4-phenylenediamine  (EXP)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (ISO)
1-chloro-2,4,6-trinitrobenzene  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2,2-trichloroethanol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-amino-2-deoxy-D-galactopyranose  (ISO)
26-hydroxycholesterol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,4-dihydroxybenzoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-phenylprop-2-enal  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxy-3-[4-(2-hydroxyphenyl)phenyl]-6-oxo-7H-thieno[2,3-b]pyridine-5-carbonitrile  (ISO)
4-hydroxynon-2-enal  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP)
6-propyl-2-thiouracil  (ISO)
7alpha-hydroxycholesterol  (EXP)
acetamide  (ISO)
acetate ester  (EXP)
acetic acid  (ISO)
acrolein  (EXP)
acrylamide  (ISO)
adenosine  (EXP)
aflatoxin B1  (EXP,ISO)
agomelatine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP)
all-trans-retinol  (EXP)
alpha-D-galactose  (ISO)
alpha-pinene  (EXP)
Alternaramide  (ISO)
aluminium hydroxide  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
anethole  (ISO)
antirheumatic drug  (EXP)
apigenin  (EXP,ISO)
arachidonic acid  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
aspalathin  (EXP)
astaxanthin  (ISO)
atazanavir sulfate  (EXP)
atorvastatin calcium  (EXP,ISO)
ATP  (ISO)
atrazine  (ISO)
auranofin  (ISO)
azathioprine  (ISO)
baicalin  (ISO)
benazepril  (EXP)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzylpenicillin  (ISO)
berberine  (ISO)
Bergenin  (ISO)
Besigomsin  (ISO)
bicalutamide  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisdemethoxycurcumin  (EXP)
Bisibuthiamine  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol F  (EXP,ISO)
boldenone  (ISO)
bortezomib  (EXP,ISO)
bosentan  (ISO)
butyric acid  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
casticin  (EXP)
catalpol  (ISO)
ceftaroline  (EXP)
cerium trichloride  (ISO)
CGP 52608  (EXP)
chaetoglobosin A  (ISO)
chenodeoxycholic acid  (EXP)
chitosan  (EXP)
chlorogenic acid  (ISO)
chloroquine  (ISO)
chlorothalonil  (EXP)
chlorpyrifos  (ISO)
cholesterol  (ISO)
choline  (ISO)
chromium atom  (EXP)
chrysin  (EXP,ISO)
cirsilineol  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (EXP)
cordycepin  (ISO)
corticosterone  (ISO)
cortisol  (EXP)
crocin-1  (ISO)
cudratricusxanthone A  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyhalothrin  (ISO)
D-glucose  (EXP,ISO)
DAPT  (ISO)
daunorubicin  (ISO)
decabromodiphenyl ether  (ISO)
dehydroepiandrosterone  (ISO)
deoxycholic acid  (EXP)
deoxynivalenol  (ISO)
desferrioxamine B  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dienogest  (EXP)
dihydrogen  (ISO)
dimethylarsinous acid  (EXP)
dioxygen  (ISO)
diprotium  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (ISO)
enalapril  (EXP)
enalaprilat dihydrate  (ISO)
erythromycin A  (ISO)
esculetin  (ISO)
ethanol  (EXP,ISO)
ethion  (ISO)
ethyl methanesulfonate  (EXP)
ethylparaben  (EXP)
eugenol  (EXP)
euxanthone  (EXP)
Fargesin  (ISO)
ferric oxide  (ISO)
ferroheme b  (ISO)
ferulic acid  (ISO)
fisetin  (ISO)
flavonoids  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
formononetin  (ISO)
fructose  (ISO)
furan  (ISO)
gadolinium trichloride  (ISO)
galactose  (ISO)
galangin  (ISO)
gallocatechin  (EXP)
gamma-hexachlorocyclohexane  (ISO)
ganglioside GM1  (ISO)
Gastrodin  (ISO)
geldanamycin  (EXP)
genistein  (ISO)
genkwanin  (EXP)
gentamycin  (ISO)
geraniol  (ISO)
Ginkgolide A  (ISO)
ginsenoside Re  (ISO)
glucose  (EXP,ISO)
glutathione  (EXP)
glyburide  (ISO)
glycerol  (ISO)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
halothane  (ISO)
Harpagide  (ISO)
helenalin  (ISO)
heme b  (ISO)
hexadecanoic acid  (ISO)
hyaluronic acid  (EXP,ISO)
hydrogen cyanide  (ISO)
hydroquinone  (ISO)
ifosfamide  (EXP)
indometacin  (EXP,ISO)
indoprofen  (EXP)
irinotecan  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
isoamylol  (ISO)
isoprenaline  (ISO)
ivermectin  (EXP)
kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside  (EXP)
kainic acid  (ISO)
ketamine  (ISO)
Kukoamine B  (ISO)
L-1,4-dithiothreitol  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lactulose  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lidocaine  (ISO)
linsidomine  (ISO)
lipophosphoglycan  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
liquiritigenin  (ISO)
liquiritin  (ISO)
lithium chloride  (ISO)
LY294002  (ISO)
lycopene  (EXP,ISO)
magnesium dihydroxide  (ISO)
malathion  (ISO)
melatonin  (ISO)
melittin  (ISO)
melphalan  (EXP)
mesalamine  (ISO)
metformin  (EXP,ISO)
methadone  (EXP,ISO)
methamphetamine  (ISO)
methimazole  (ISO)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (EXP)
methylisothiazolinone  (EXP)
Methylthiouracil  (EXP)
metronidazole  (ISO)
mirabegron  (ISO)
mirtazapine  (ISO)
monocrotaline  (ISO)
monodansylcadaverine  (ISO)
morphine  (EXP,ISO)
Morphine-3-glucuronide  (EXP,ISO)
Morroniside  (ISO)
muramyl dipeptide  (EXP,ISO)
myo-inositol hexakisphosphate  (EXP)
myrtenol  (ISO)
N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (EXP)
naloxone  (EXP)
naproxen  (ISO)
nefazodone  (EXP)
neomycin  (ISO)
nerolidol  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (EXP,ISO)
nicorandil  (ISO)
nicotine  (EXP,ISO)
nitric oxide  (ISO)
Nonidet P-40  (EXP)
Nonylphenol  (ISO)
o-anisidine  (EXP)
obeticholic acid  (ISO)
omeprazole  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PD 0325901  (EXP)
pelargonidin  (EXP)
pentachlorophenol  (EXP)
Pentoxifylline  (ISO)
perampanel  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
perindopril  (ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenylmercury acetate  (EXP)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phosphatidylinositol dimannoside  (ISO)
phosphoramide mustard  (ISO)
picropodophyllotoxin  (ISO)
pipoxolan  (ISO)
pirinixic acid  (ISO)
platycodin D  (ISO)
polymyxin B2  (EXP)
potassium chromate  (EXP)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
probenecid  (ISO)
procyanidin B1  (EXP)
progesterone  (EXP)
propofol  (ISO)
puerarin  (ISO)
Pyridostigmine bromide  (ISO)
quercetin  (EXP,ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
rosmarinic acid  (ISO)
rotenone  (ISO)
S-allylcysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
Salvianolic acid A  (ISO)
salvianolic acid B  (ISO)
SB 431542  (EXP)
scoparone  (ISO)
scopoletin  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP,ISO)
sodium acetate trihydrate  (ISO)
sodium arsenite  (EXP,ISO)
sodium cholate  (ISO)
sodium propionate  (ISO)
streptozocin  (EXP,ISO)
succimer  (ISO)
sulfadimethoxine  (ISO)
sulfasalazine  (ISO)
sulforaphane  (EXP,ISO)
sulfur dioxide  (EXP)
sumatriptan  (ISO)
tartrazine  (EXP)
tectorigenin  (ISO)
telmisartan  (EXP)
temozolomide  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetrachloropalladate(2-)  (EXP)
thiamine(1+) chloride  (ISO)
thioacetamide  (ISO)
thymoquinone  (EXP,ISO)
Timosaponin b ii  (ISO)
titanium atom  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
trans-anethole  (ISO)
trichloroethene  (ISO)
tropisetron  (ISO)
ubiquinone-0  (EXP)
valproic acid  (EXP)
vancomycin  (ISO)
vinclozolin  (ISO)
Vinpocetine  (ISO)
vitamin D  (EXP,ISO)
Y-27632  (EXP)
zinc atom  (ISO)
zinc oxide  (ISO)
zinc protoporphyrin  (ISO)
zinc(0)  (ISO)
zingerone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of innate immune response  (IEA,ISO)
astrocyte development  (IEA,ISO)
B cell proliferation  (IEA,ISO)
B cell proliferation involved in immune response  (IEA,ISO)
cellular response to amyloid-beta  (IDA,IGI)
cellular response to lipopolysaccharide  (IDA,IEA,IGI,ISO,ISS)
cellular response to lipoteichoic acid  (IEA,ISO)
cellular response to mechanical stimulus  (IEP,ISO)
cellular response to oxidised low-density lipoprotein particle stimulus  (IDA,IEA,ISS)
cellular response to platelet-derived growth factor stimulus  (IEA)
cellular response to retinoic acid  (ISO)
cellular response to type II interferon  (IDA)
defense response to bacterium  (TAS)
defense response to Gram-negative bacterium  (IBA,IC,IEA,ISO)
detection of fungus  (NAS)
detection of lipopolysaccharide  (IBA,IDA,IEA)
detection of mechanical stimulus involved in sensory perception of pain  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (ISO)
ERK1 and ERK2 cascade  (IEA,ISO)
gene expression  (IEA,ISO)
immune response  (IEA,TAS)
immunoglobulin mediated immune response  (ISO)
inflammatory response  (IBA,IEA,ISO)
innate immune response  (IEA,NAS,TAS)
innate immune response-activating signaling pathway  (ISO)
intestinal epithelial structure maintenance  (IEA,ISS)
JNK cascade  (IEA,ISO)
leukotriene metabolic process  (ISO)
lipopolysaccharide-mediated signaling pathway  (IDA,IEA,IGI)
lymphocyte proliferation  (IEA,ISO)
macrophage activation  (IMP)
MHC class II biosynthetic process  (IEA,ISO)
microglia differentiation  (IEA,ISO)
microglial cell activation  (ISO)
MyD88-dependent toll-like receptor signaling pathway  (IBA,IDA,IEA,ISS)
negative regulation of cold-induced thermogenesis  (IEA,ISS)
negative regulation of ERK1 and ERK2 cascade  (IEA,ISS)
negative regulation of interleukin-17 production  (IEA,ISS)
negative regulation of interleukin-23 production  (IEA,ISS)
negative regulation of interleukin-6 production  (IEA,ISS)
negative regulation of osteoclast differentiation  (NAS)
negative regulation of tumor necrosis factor production  (IEA,ISS)
negative regulation of type II interferon production  (IEA,ISS)
neurogenesis  (IEA,ISO)
nitric oxide biosynthetic process  (IEA,ISO)
nitric oxide production involved in inflammatory response  (IEA,ISO)
nucleotide-binding oligomerization domain containing 1 signaling pathway  (IEA,ISO)
nucleotide-binding oligomerization domain containing 2 signaling pathway  (IEA,ISO)
phagocytosis  (IDA)
positive regulation of apoptotic process  (ISO)
positive regulation of B cell proliferation  (IEA,ISO)
positive regulation of canonical NF-kappaB signal transduction  (IEA,IGI,ISO)
positive regulation of cellular response to macrophage colony-stimulating factor stimulus  (IDA)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (IMP)
positive regulation of chemokine production  (IDA,IEA)
positive regulation of cytokine production involved in inflammatory response  (IEA,IMP,ISS)
positive regulation of DNA binding  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IEA,ISO)
positive regulation of extrinsic apoptotic signaling pathway  (IEA,ISS)
positive regulation of gene expression  (IEA,IMP,ISO,ISS)
positive regulation of inflammatory response  (IC,IEA,IMP)
positive regulation of interferon-alpha production  (IEA,ISS)
positive regulation of interferon-beta production  (IEA,ISO,ISS)
positive regulation of interleukin-1 beta production  (IDA,IEA,ISS)
positive regulation of interleukin-1 production  (IEA,ISS)
positive regulation of interleukin-10 production  (IEA,ISO,ISS)
positive regulation of interleukin-12 production  (IDA,IEA,ISS)
positive regulation of interleukin-6 production  (IDA,IEA,IMP,ISO)
positive regulation of interleukin-8 production  (IDA)
positive regulation of JNK cascade  (IEA,ISO)
positive regulation of lymphocyte proliferation  (IEA,ISO)
positive regulation of macrophage activation  (IEA,ISS)
positive regulation of macrophage cytokine production  (IEA,ISO)
positive regulation of matrix metallopeptidase secretion  (IMP)
positive regulation of MHC class II biosynthetic process  (IEA,ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of nitric oxide biosynthetic process  (IEA,ISO,ISS)
positive regulation of nitric-oxide synthase biosynthetic process  (IEA,ISS)
positive regulation of NLRP3 inflammasome complex assembly  (IEA,ISS)
positive regulation of non-canonical NF-kappaB signal transduction  (IDA)
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway  (IEA,ISO)
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway  (IEA,ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of platelet activation  (IEA,ISS)
positive regulation of reactive oxygen species biosynthetic process  (IEA,ISS)
positive regulation of smooth muscle cell migration  (IEA,ISO)
positive regulation of smooth muscle cell proliferation  (IEA,ISO)
positive regulation of stress-activated MAPK cascade  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISS)
positive regulation of tumor necrosis factor production  (IDA,IEA,IMP,ISO,ISS)
positive regulation of type II interferon production  (IEA,ISS)
regulation of dendritic cell cytokine production  (IEA,ISO)
regulation of inflammatory response  (IEA)
regulation of tumor necrosis factor production  (ISO)
response to activity  (ISO)
response to bacterium  (IEA,ISO)
response to ethanol  (ISO)
response to fatty acid  (ISO)
response to glucocorticoid  (ISO)
response to gold nanoparticle  (ISO)
response to hypoxia  (ISO)
response to insulin  (ISO)
response to lipopolysaccharide  (IC,IDA,IEA,ISO)
response to oxidative stress  (ISO)
response to progesterone  (ISO)
response to retinoic acid  (ISO)
response to toxic substance  (ISO)
skeletal muscle contraction  (ISO)
stress-activated MAPK cascade  (IEA,ISO)
T-helper 1 type immune response  (NAS)
toll-like receptor 4 signaling pathway  (IBA,IDA,IEA,ISO)
toll-like receptor signaling pathway  (IDA,IEA,ISO)
TRIF-dependent toll-like receptor signaling pathway  (IEA,ISS)
wound healing involved in inflammatory response  (IEA)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abdominal pain  (IAGP)
Abnormal blistering of the skin  (IAGP)
Abnormal delayed hypersensitivity skin test  (IAGP)
Abnormal myocardium morphology  (IAGP)
Abnormal pyramidal sign  (IAGP)
Abnormality of the urinary system  (IAGP)
Acne  (IAGP)
Anorexia  (IAGP)
Aortic regurgitation  (IAGP)
Arterial thrombosis  (IAGP)
Arthralgia  (IAGP)
Arthritis  (IAGP)
Ataxia  (IAGP)
Atypical behavior  (IAGP)
Avascular necrosis  (IAGP)
Blindness  (IAGP)
Cataract  (IAGP)
Cerebral ischemia  (IAGP)
Confusion  (IAGP)
Cranial nerve paralysis  (IAGP)
Developmental regression  (IAGP)
Endocarditis  (IAGP)
Fatigue  (IAGP)
Fever  (IAGP)
Gait disturbance  (IAGP)
Gangrene  (IAGP)
Gastrointestinal hemorrhage  (IAGP)
Glomerulopathy  (IAGP)
Hemiparesis  (IAGP)
Hemoptysis  (IAGP)
Hyperreflexia  (IAGP)
Immunologic hypersensitivity  (IAGP)
Increased circulating IgE level  (IAGP)
Increased inflammatory response  (IAGP)
Increased intracranial pressure  (IAGP)
Infectious encephalitis  (IAGP)
Irritability  (IAGP)
Keratoconjunctivitis sicca  (IAGP)
Lung adenocarcinoma  (IAGP)
Lymphadenopathy  (IAGP)
Malabsorption  (IAGP)
Memory impairment  (IAGP)
Meningitis  (IAGP)
Migraine  (IAGP)
Mitral regurgitation  (IAGP)
Myalgia  (IAGP)
Myocardial infarction  (IAGP)
Myositis  (IAGP)
Nausea and vomiting  (IAGP)
Optic neuritis  (IAGP)
Oral ulcer  (IAGP)
Orchitis  (IAGP)
Pancreatitis  (IAGP)
Papule  (IAGP)
Paresthesia  (IAGP)
Pericarditis  (IAGP)
Photophobia  (IAGP)
Pleural effusion  (IAGP)
Pleuritis  (IAGP)
Pulmonary embolism  (IAGP)
Pulmonary infiltrates  (IAGP)
Recurrent aphthous stomatitis  (IAGP)
Renal insufficiency  (IAGP)
Retinopathy  (IAGP)
Retrobulbar optic neuritis  (IAGP)
Seizure  (IAGP)
Splenomegaly  (IAGP)
Squamous cell carcinoma  (IAGP)
Subcutaneous nodule  (IAGP)
Vasculitis  (IAGP)
Venous thrombosis  (IAGP)
Vertigo  (IAGP)
Weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
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2. Serum Toll-Like Receptor-2, Toll-Like Receptor-4 Levels in Patients with HBeAg-Negative Chronic Viral Hepatitis B. Akbal E, etal., Viral Immunol. 2017 May;30(4):278-282. doi: 10.1089/vim.2016.0131. Epub 2017 Apr 17.
3. Gingerol protects against experimental liver fibrosis in rats via suppression of pro-inflammatory and profibrogenic mediators. Algandaby MM, etal., Naunyn Schmiedebergs Arch Pharmacol. 2016 Apr;389(4):419-28. doi: 10.1007/s00210-016-1210-1. Epub 2016 Jan 26.
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6. Lack of association between Toll-like receptor 4 gene polymorphisms and giant cell arteritis. Alvarez-Rodriguez L, etal., Rheumatology (Oxford). 2011 Sep;50(9):1562-8. doi: 10.1093/rheumatology/ker168. Epub 2011 May 17.
7. Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis. Andersson A, etal., J Leukoc Biol. 2008 Nov;84(5):1248-55. Epub 2008 Jul 21.
8. Whole-blood gene expression profiling in ankylosing spondylitis shows upregulation of toll-like receptor 4 and 5. Assassi S, etal., J Rheumatol. 2011 Jan;38(1):87-98. doi: 10.3899/jrheum.100469. Epub 2010 Oct 15.
9. Systemic Toll-like receptor stimulation suppresses experimental allergic asthma and autoimmune diabetes in NOD mice. Aumeunier A, etal., PLoS One. 2010 Jul 7;5(7):e11484.
10. Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children. Awomoyi AA, etal., J Immunol. 2007 Sep 1;179(5):3171-7.
11. Toll-like receptor 4 and inducible nitric oxide synthase gene polymorphisms are associated with Type 2 diabetes. Bagarolli RA, etal., J Diabetes Complications. 2009 Apr 21.
12. TLR4 links podocytes with the innate immune system to mediate glomerular injury. Banas MC, etal., J Am Soc Nephrol. 2008 Apr;19(4):704-13. doi: 10.1681/ASN.2007040395. Epub 2008 Feb 6.
13. Toll-like-receptor gene polymorphisms in a Tunisian population with Behcet's disease. Ben Dhifallah I, etal., Clin Exp Rheumatol. 2009 Mar-Apr;27(2 Suppl 53):S58-62.
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15. Influence of perineurial cells and Toll-like receptors 2 and 9 on Herpes simplex type 1 entry to the central nervous system in rat encephalitis. Bereczky-Veress B, etal., PLoS One. 2010 Aug 27;5(8):e12350.
16. Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice. Bettoni I, etal., Glia. 2008 Sep;56(12):1312-9. doi: 10.1002/glia.20699.
17. Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury. Boivin A, etal., J Neurosci. 2007 Nov 14;27(46):12565-76.
18. Expression of Toll-like receptors in healthy and allergic conjunctiva. Bonini S, etal., Ophthalmology. 2005 Sep;112(9):1528; discussion 1548-9.
19. Differential regulation of Toll-like receptor mRNAs in experimental murine central nervous system infections. Bottcher T, etal., Neurosci Lett. 2003 Jun 19;344(1):17-20.
20. MyD88 signaling pathway is involved in renal fibrosis by favoring a TH2 immune response and activating alternative M2 macrophages. Braga TT, etal., Mol Med. 2012 Oct 24;18:1231-9. doi: 10.2119/molmed.2012.00131.
21. TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis. Brown HJ, etal., J Immunol. 2006 Aug 1;177(3):1925-31.
22. Toll-like receptor 4 gene polymorphism and early onset of diabetic retinopathy in patients with type 2 diabetes. Buraczynska M, etal., Hum Immunol. 2009 Feb;70(2):121-4. Epub 2009 Jan 7.
23. Toll-like receptor-4 genotype influences the survival of cystic fibrosis mice. Canale-Zambrano JC, etal., Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G381-90. Epub 2010 Jun 3.
24. Polymorphisms in toll-like receptor genes and susceptibility to pulmonary aspergillosis. Carvalho A, etal., J Infect Dis. 2008 Feb 15;197(4):618-21.
25. Safety of the intranasal toll-like receptor 4 agonist CRX-675 in allergic rhinitis. Casale TB, etal., Ann Allergy Asthma Immunol. 2006 Oct;97(4):454-6.
26. TLR2, TLR4 and the MYD88 signaling pathway are crucial for neutrophil migration in acute kidney injury induced by sepsis. Castoldi A, etal., PLoS One. 2012;7(5):e37584. doi: 10.1371/journal.pone.0037584. Epub 2012 May 24.
27. Changes in Toll-like receptor (TLR)-2 and TLR4 expression and function but not polymorphisms are associated with acute anterior uveitis. Chang JH, etal., Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1711-7.
28. TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans. Chassin C, etal., J Immunol. 2009 Aug 15;183(4):2669-77. doi: 10.4049/jimmunol.0900506. Epub 2009 Jul 27.
29. Toll-like receptor 4 regulates heme oxygenase-1 expression after hemorrhagic shock induced acute lung injury in mice: requirement of p38 mitogen-activated protein kinase activation. Chen C, etal., Shock. 2009 May;31(5):486-92.
30. Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion. Chen G, etal., Ann Clin Lab Sci. 2008 Winter;38(1):65-74.
31. Expression of toll-like receptor 4 in uvea-resident tissue macrophages during endotoxin-induced uveitis. Chen W, etal., Mol Vis. 2009;15:619-28. Epub 2009 Mar 30.
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33. Effect of Toll-like receptor 4 gene polymorphisms on work-related respiratory symptoms and sensitization to wheat flour in bakery workers. Cho HJ, etal., Ann Allergy Asthma Immunol. 2011 Jul;107(1):57-64. doi: 10.1016/j.anai.2011.04.003. Epub 2011 May 19.
34. Toll-like receptor polymorphisms and age-related macular degeneration: replication in three case-control samples. Cho Y, etal., Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5614-8. doi: 10.1167/iovs.09-3688. Epub 2009 Jul 23.
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36. Pivotal role of Toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritis. Correa-Costa M, etal., PLoS One. 2011;6(12):e29004. doi: 10.1371/journal.pone.0029004. Epub 2011 Dec 14.
37. A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype. Cundy T, etal., Hum Mol Genet. 2002 Sep 1;11(18):2119-27.
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39. Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance. Deng ZB, etal., Diabetes. 2009 Aug 12.
40. Comprehensive analysis of the candidate genes CCL2, CCR2, and TLR4 in age-related macular degeneration. Despriet DD, etal., Invest Ophthalmol Vis Sci. 2008 Jan;49(1):364-71. doi: 10.1167/iovs.07-0656.
41. Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. Devaraj S, etal., J Clin Endocrinol Metab. 2008 Feb;93(2):578-83. Epub 2007 Nov 20.
42. Toll-like receptor 4 regulates platelet function and contributes to coagulation abnormality and organ injury in hemorrhagic shock and resuscitation. Ding N, etal., Circ Cardiovasc Genet. 2014 Oct;7(5):615-24. doi: 10.1161/CIRCGENETICS.113.000398. Epub 2014 Jul 21.
43. Regulation by 1, 25-dihydroxy-vitamin D3 on altered TLRs expression and response to ligands of monocyte from autoimmune diabetes. Du T, etal., Clin Chim Acta. 2009 Apr;402(1-2):133-8. Epub 2009 Jan 11.
44. Modulation of monocyte hyperresponsiveness to TLR ligands by 1,25-dihydroxy-vitamin D3 from LADA and T2DM. Du T, etal., Diabetes Res Clin Pract. 2009 Feb;83(2):208-14. Epub 2008 Nov 17.
45. Toll-like receptor 4 contributes to retinal ischemia/reperfusion injury. Dvoriantchikova G, etal., Mol Vis. 2010 Sep 30;16:1907-12.
46. Significant correlation of TLR4 expression with the clinicopathological features of invasive ductal carcinoma of the breast. Ehsan N, etal., Tumour Biol. 2013 Apr;34(2):1053-9. doi: 10.1007/s13277-013-0645-y. Epub 2013 Jan 22.
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48. Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke. Enquobahrie DA, etal., Am J Cardiol. 2008 Jun 15;101(12):1683-8. Epub 2008 Apr 9.
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50. A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children. Fageras Bottcher M, etal., J Allergy Clin Immunol. 2004 Sep;114(3):561-7.
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53. Differential effect of insulin treatment on decreased levels of beta-defensins and Toll-like receptors in diabetic rats. Froy O, etal., Mol Immunol. 2007 Feb;44(5):796-802. Epub 2006 Jun 5.
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56. TLR4 mediates early graft failure after intraportal islet transplantation. Gao Q, etal., Am J Transplant. 2010 Jul;10(7):1588-96. doi: 10.1111/j.1600-6143.2010.03151.x.
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58. TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. Garantziotis S, etal., Am J Respir Crit Care Med. 2010 Apr 1;181(7):666-75. Epub 2009 Dec 10.
59. Increased gene expression of Toll-like receptor 4 on peripheral blood mononuclear cells in patients with psoriasis. Garcia-Rodriguez S, etal., J Eur Acad Dermatol Venereol. 2013 Feb;27(2):242-50.
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61. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
62. Single nucleotide polymorphisms of toll-like receptor-4 protect against acne conglobata. Grech I, etal., J Eur Acad Dermatol Venereol. 2012 Dec;26(12):1538-43. doi: 10.1111/j.1468-3083.2011.04338.x. Epub 2011 Nov 16.
63. Combinations of TLR and NOD2 ligands stimulate rat microglial P2X4R expression. Guo LH, etal., Biochem Biophys Res Commun. 2006 Oct 27;349(3):1156-62. Epub 2006 Sep 1.
64. Neutrophil TLR4 expression is reduced in the airways of infants with severe bronchiolitis. Halfhide CP, etal., Thorax. 2009 Sep;64(9):798-805. Epub 2009 Jun 3.
65. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Hammad H, etal., Nat Med. 2009 Apr;15(4):410-6. Epub 2009 Mar 29.
66. Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women. Hawn TR, etal., PLoS One. 2009 Jun 22;4(6):e5990. doi: 10.1371/journal.pone.0005990.
67. Resveratrol preconditioning protects hepatocytes against hepatic ischemia reperfusion injury via Toll-like receptor 4/nuclear factor-κB signaling pathway in vitro and in vivo. He D, etal., Int Immunopharmacol. 2016 Jun;35:201-209. doi: 10.1016/j.intimp.2016.03.032. Epub 2016 Apr 16.
68. Inhibiting toll-like receptor 4 signaling ameliorates pulmonary fibrosis during acute lung injury induced by lipopolysaccharide: an experimental study. He Z, etal., Respir Res. 2009 Dec 18;10:126.
69. Exacerbation of murine ileitis by Toll-like receptor 4 mediated sensing of lipopolysaccharide from commensal Escherichia coli. Heimesaat MM, etal., Gut. 2007 Jul;56(7):941-8. Epub 2007 Jan 25.
70. Expression of toll-like receptors in chronic otitis media and cholesteatoma. Hirai H, etal., Int J Pediatr Otorhinolaryngol. 2013 May;77(5):674-6. doi: 10.1016/j.ijporl.2013.01.010. Epub 2013 Feb 4.
71. Bone marrow and nonbone marrow Toll like receptor 4 regulate acute hepatic injury induced by endotoxemia. Hochhauser E, etal., PLoS One. 2013 Aug 15;8(8):e73041. doi: 10.1371/journal.pone.0073041. eCollection 2013.
72. Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction. Holloway JW, etal., Pharmacogenet Genomics. 2005 Jan;15(1):15-21.
73. Association of TLR4 polymorphisms with Behcet's disease in a Korean population. Horie Y, etal., Rheumatology (Oxford). 2009 Jun;48(6):638-42. doi: 10.1093/rheumatology/kep077. Epub 2009 Apr 24.
74. STAT2*C related genotypes and allele but not TLR4 and CD40 gene polymorphisms are associated with higher susceptibility for asthma. Hsieh YY, etal., Int J Biol Sci. 2009;5(1):74-81. Epub 2009 Jan 9.
75. Potential role of macrophages in experimental keratomycosis. Hu J, etal., Invest Ophthalmol Vis Sci. 2009 May;50(5):2087-94. doi: 10.1167/iovs.07-1237. Epub 2008 Dec 13.
76. Expression of Toll-like receptor 4 in rat liver during the course of carbon tetrachloride-induced liver injury. Hua J, etal., J Gastroenterol Hepatol. 2007 Jun;22(6):862-9. doi: 10.1111/j.1440-1746.2007.04896.x. Epub 2007 May 17.
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78. TLR4 is required for host resistance in Pseudomonas aeruginosa keratitis. Huang X, etal., Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4910-6.
79. Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and susceptibility to asthma and allergic rhinitis: a case-control analysis. Hussein YM, etal., Cell Immunol. 2012;274(1-2):34-8. doi: 10.1016/j.cellimm.2012.02.006. Epub 2012 Feb 17.
80. Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). Hutchinson MR, etal., Eur J Neurosci. 2008 Jul;28(1):20-9.
81. The endotoxin receptor TLR4 polymorphism is not associated with diabetes or components of the metabolic syndrome. Illig T, etal., Diabetes. 2003 Nov;52(11):2861-4.
82. Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury. Impellizzeri D, etal., Immunobiology. 2015 Sep;220(9):1039-49. doi: 10.1016/j.imbio.2015.05.013. Epub 2015 May 11.
83. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Inokuchi S, etal., Alcohol Clin Exp Res. 2011 Aug;35(8):1509-18. doi: 10.1111/j.1530-0277.2011.01487.x. Epub 2011 Apr 4.
84. Expression of Toll-Like Receptors 2, 4 and Nuclear Factor Kappa B in Mucosal Lesions of Human Otitis: Pattern and Relationship in a Clinical Immunohistochemical Study. Jesic S, etal., Ann Otol Rhinol Laryngol. 2014 Apr 1.
85. Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury. Jeyaseelan S, etal., Infect Immun. 2005 Mar;73(3):1754-63.
86. Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease. Jia L, etal., Mol Metab. 2018 Aug;14:121-129. doi: 10.1016/j.molmet.2018.05.015. Epub 2018 May 23.
87. Inhibition of Toll-like receptor 4 with vasoactive intestinal peptide attenuates liver ischemia-reperfusion injury. Jiang W, etal., Transplant Proc. 2011 Jun;43(5):1462-7.
88. A functional variant at miR-34a binding site in toll-like receptor 4 gene alters susceptibility to hepatocellular carcinoma in a Chinese Han population. Jiang ZC, etal., Tumour Biol. 2014 Dec;35(12):12345-52. doi: 10.1007/s13277-014-2547-z. Epub 2014 Sep 2.
89. Activation of Toll-like receptors 2 and 4 in Aspergillus fumigatus keratitis. Jie Zhao, etal., Innate Immun. 2009 Jun;15(3):155-68.
90. Expression of toll-like receptors in the healthy and herpes simplex virus-infected cornea. Jin X, etal., Cornea. 2007 Aug;26(7):847-52.
91. Expression of toll-like receptors in the Fusarium solani infected cornea. Jin X, etal., Curr Eye Res. 2008 Apr;33(4):319-24. doi: 10.1080/02713680802008238.
92. The delayed response of Toll-like receptors may relate to Pseudomonas aeruginosa keratitis exacerbating rapidly at the early stages of infection. Jin X, etal., Eur J Clin Microbiol Infect Dis. 2010 Feb;29(2):231-8. doi: 10.1007/s10096-009-0844-z. Epub 2009 Dec 13.
93. [Effects of intestinal trefoil factor on Toll-like receptors 2 and 4 expression in intestinal tissue in young rats with endotoxemia]. Jing K and Sun M, Zhongguo Dang Dai Er Ke Za Zhi. 2011 Dec;13(12):985-8.
94. Identification of polymorphisms in the Toll-like receptor gene and the association with allergic rhinitis. Kang I, etal., Eur Arch Otorhinolaryngol. 2010 Mar;267(3):385-9. Epub 2009 Sep 18.
95. TLR2 and TLR4 gene polymorphisms in Turkish vitiligo patients. Karaca N, etal., J Eur Acad Dermatol Venereol. 2013 Jan;27(1):e85-90. doi: 10.1111/j.1468-3083.2012.04514.x. Epub 2012 Mar 16.
96. Enhanced TLR4 endothelial cell immunohistochemical expression in symptomatic carotid atherosclerotic plaques. Katsargyris A, etal., Expert Opin Ther Targets. 2010 Jan;14(1):1-10. doi: 10.1517/14728220903401294.
97. Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma. Kerkhof M, etal., Thorax. 2010 Aug;65(8):690-7.
98. Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis. Kim GT, etal., Clin Rheumatol. 2010 Mar;29(3):273-9. doi: 10.1007/s10067-009-1316-7. Epub 2009 Dec 2.
99. Dietary omega-3 polyunsaturated fatty acids attenuate hepatic ischemia/reperfusion injury in rats by modulating toll-like receptor recruitment into lipid rafts. Kim K, etal., Clin Nutr. 2013 Oct;32(5):855-62. doi: 10.1016/j.clnu.2012.11.026. Epub 2013 Jan 23.
100. Toll-like receptor 4: a potential link between "danger signals," the innate immune system, and preeclampsia? Kim YM, etal., Am J Obstet Gynecol. 2005 Sep;193(3 Pt 2):921-7.
101. Association of reduced heme oxygenase-1 with excessive Toll-like receptor 4 expression in peripheral blood mononuclear cells in Behcet's disease. Kirino Y, etal., Arthritis Res Ther. 2008;10(1):R16. doi: 10.1186/ar2367. Epub 2008 Jan 31.
102. Expression of Toll-like receptor 4 in various organs in rats with D-galactosamine-induced acute hepatic failure. Kitazawa T, etal., J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e494-8. Epub 2007 Dec 7.
103. Salvage effect of E5564, Toll-like receptor 4 antagonist on d-galactosamine and lipopolysaccharide-induced acute liver failure in rats. Kitazawa T, etal., J Gastroenterol Hepatol. 2010 May;25(5):1009-12. doi: 10.1111/j.1440-1746.2009.06145.x.
104. Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia. Knapp S, etal., Am J Respir Crit Care Med. 2006 Jan 1;173(1):122-9. Epub 2005 Oct 6.
105. Toll-like receptor expression in monocytes in patients with chronic kidney disease and haemodialysis: relation with inflammation. Koc M, etal., Nephrol Dial Transplant. 2011 Mar;26(3):955-63. doi: 10.1093/ndt/gfq500. Epub 2010 Aug 20.
106. Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. Kolek MJ, etal., Am Heart J. 2004 Dec;148(6):1034-40.
107. TLR2 and TLR4 polymorphisms are not associated with acne vulgaris. Koreck A, etal., Dermatology. 2006;213(3):267-9.
108. Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats. Kuang X, etal., Eur J Pharmacol. 2012 Feb 15;676(1-3):51-6. doi: 10.1016/j.ejphar.2011.11.037. Epub 2011 Dec 7.
109. Pathogen recognition by the innate immune system. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
110. TLR 2 and 4 responsiveness from isolated peripheral blood mononuclear cells from rats and humans as potential chronic pain biomarkers. Kwok YH, etal., PLoS One. 2013 Oct 30;8(10):e77799. doi: 10.1371/journal.pone.0077799. eCollection 2013.
111. Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus. Lartigue A, etal., J Immunol. 2009 Nov 15;183(10):6207-16. doi: 10.4049/jimmunol.0803219. Epub 2009 Oct 19.
112. TLR4 and TLR9 Expression in Different Phenotypes of Rhinitis. Lauriello M, etal., Int J Otolaryngol. 2012;2012:925164. doi: 10.1155/2012/925164. Epub 2012 Apr 10.
113. Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis. Leal SM Jr, etal., PLoS Pathog. 2010 Jul 1;6:e1000976. doi: 10.1371/journal.ppat.1000976.
114. TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media. Leichtle A, etal., Innate Immun. 2009 Aug;15(4):205-15. doi: 10.1177/1753425909103170. Epub 2009 Jul 8.
115. [Polymorphism 896A/G of TLR4 gene rather than 1196C/T and 2258G/A of TLR2 gene determines severe and complicated course of atopic dermatitis in children]. Levchenko LIu, etal., Tsitol Genet. 2013 May-Jun;47(3):46-53.
116. Modulating Toll-like receptor mediated signaling by (1-->3)-beta-D-glucan rapidly induces cardioprotection. Li C, etal., Cardiovasc Res 2004 Feb 15;61(3):538-47.
117. Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4-dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways. Li DQ, etal., J Allergy Clin Immunol. 2011 Dec;128(6):1318-1325.e2. doi: 10.1016/j.jaci.2011.06.041. Epub 2011 Aug 6.
118. Toll-like receptor 4-myeloid differentiation factor 88 signaling contributes to ventilator-induced lung injury in mice. Li H, etal., Anesthesiology. 2010 Sep;113(3):619-29.
119. [Toll-like receptor 2 and Toll-like receptor 4 participates in mediation of acute otitis media and mortality in pneumococcal infections in mice]. Li SL, etal., Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Dec;46(12):1009-18.
120. Blockade of high-mobility group box-1 ameliorates acute on chronic liver failure in rats. Li X, etal., Inflamm Res. 2013 Jul;62(7):703-9. doi: 10.1007/s00011-013-0624-1. Epub 2013 Apr 17.
121. Quercetin attenuates the activation of hepatic stellate cells and liver fibrosis in mice through modulation of HMGB1-TLR2/4-NF-κB signaling pathways. Li X, etal., Toxicol Lett. 2016 Nov 2;261:1-12. doi: 10.1016/j.toxlet.2016.09.002. Epub 2016 Sep 4.
122. Down-Regulation of CXCL12/CXCR4 Expression Alleviates Ischemia-Reperfusion-Induced Inflammatory Pain via Inhibiting Glial TLR4 Activation in the Spinal Cord. Li XQ, etal., PLoS One. 2016 Oct 19;11(10):e0163807. doi: 10.1371/journal.pone.0163807. eCollection 2016.
123. Cyclosporine-induced renal injury induces toll-like receptor and maturation of dendritic cells. Lim SW, etal., Transplantation. 2005 Sep 15;80(5):691-9.
124. Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy. Lin M, etal., J Am Soc Nephrol. 2012 Jan;23(1):86-102. doi: 10.1681/ASN.2010111210. Epub 2011 Oct 21.
125. TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats. Lin ZP, etal., Mol Med Rep. 2020 Aug;22(2):651-660. doi: 10.3892/mmr.2020.11134. Epub 2020 May 7.
126. HMGB1 in ischemic and non-ischemic liver after selective warm ischemia/reperfusion in rat. Liu A, etal., Histochem Cell Biol. 2011 May;135(5):443-52. doi: 10.1007/s00418-011-0802-6. Epub 2011 Mar 24.
127. Changes in gut toll-like receptor-4 and nod-like receptor family pyrin domain containing-3 innate pathways in liver cirrhosis rats with bacterial translocation. Liu L, etal., Clin Res Hepatol Gastroenterol. 2016 Nov;40(5):575-583. doi: 10.1016/j.clinre.2016.02.008. Epub 2016 Apr 6.
128. Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis. Liu Y, etal., Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G442-50. Epub 2009 Jul 16.
129. [Effects of antimicrobial agents on the Toll like receptors and myeloid differentiation protein-2 in liver tissue of alcohol-induced liver disease: experiment with rats] Lu ZQ, etal., Zhonghua Yi Xue Za Zhi. 2009 Jan 13;89(2):138-41.
130. Curcumin attenuates inflammation through inhibition of TLR-4 receptor in experimental colitis. Lubbad A, etal., Mol Cell Biochem. 2009 Feb;322(1-2):127-35. Epub 2008 Nov 11.
131. Expression and functional analysis of toll-like receptors of peripheral blood cells in asthmatic patients: implication for immunopathological mechanism in asthma. Lun SW, etal., J Clin Immunol. 2009 May;29(3):330-42. Epub 2008 Dec 6.
132. Evaluation of importance of Toll-like receptor 4 in acute Streptococcus pneumoniae sinusitis in mice. Luxameechanporn T, etal., Arch Otolaryngol Head Neck Surg. 2005 Nov;131(11):1001-6.
133. Toll-like receptor 4/nuclear factor-kappa B signaling detected in brain after early subarachnoid hemorrhage. Ma CX, etal., Chin Med J (Engl). 2009 Jul 5;122(13):1575-81.
134. The innate immune response to Entamoeba histolytica lipopeptidophosphoglycan is mediated by toll-like receptors 2 and 4. Maldonado-Bernal C, etal., Parasite Immunol. 2005 Apr;27(4):127-37.
135. Comparison of Cellular Uptake and Inflammatory Response via Toll-Like Receptor 4 to Lipopolysaccharide and Titanium Dioxide Nanoparticles. Mano SS, etal., Int J Mol Sci. 2013 Jun 26;14(7):13154-70. doi: 10.3390/ijms140713154.
136. Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity. Martin SF, etal., J Exp Med. 2008 Sep 1;205(9):2151-62. doi: 10.1084/jem.20070509. Epub 2008 Aug 25.
137. Association of the toll-like receptor 4 gene polymorphisms with Behcet's disease. Meguro A, etal., Ann Rheum Dis. 2008 May;67(5):725-7. doi: 10.1136/ard.2007.079871.
138. Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome. Methe H, etal., Circulation. 2005 May 24;111(20):2654-61. Epub 2005 May 9.
139. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity. Milanski M, etal., J Neurosci. 2009 Jan 14;29(2):359-70.
140. In situ TLR2 and TLR4 expression in a murine model of mycetoma caused by Nocardia brasiliensis. Millan-Chiu BE, etal., FEMS Immunol Med Microbiol. 2011 Apr;61(3):278-87. doi: 10.1111/j.1574-695X.2010.00775.x. Epub 2011 Jan 31.
141. Single nucleotide polymorphisms of Toll-like receptor 4 decrease the risk of development of hepatocellular carcinoma. Minmin S, etal., PLoS One. 2011 Apr 29;6(4):e19466. doi: 10.1371/journal.pone.0019466.
142. Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease. Minoretti P, etal., Neurosci Lett. 2006 Jan 2;391(3):147-9. Epub 2005 Sep 12.
143. Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse. Mohammad MK, etal., Int Immunol. 2006 Jul;18(7):1101-13. Epub 2006 May 25.
144. Respiratory syncytial virus activates innate immunity through Toll-like receptor 2. Murawski MR, etal., J Virol. 2009 Feb;83(3):1492-500. Epub 2008 Nov 19.
145. Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population. Najmi N, etal., Tissue Antigens. 2010 Aug;76(2):102-9. Epub 2010 Apr 8.
146. Involvement of innate immunity in the pathogenesis of intestinal Behcet's disease. Nara K, etal., Clin Exp Immunol. 2008 May;152(2):245-51. doi: 10.1111/j.1365-2249.2008.03626.x. Epub 2008 Mar 10.
147. Toll-like receptor 4 signaling in trigeminal ganglion neurons contributes tongue-referred pain associated with tooth pulp inflammation. Ohara K, etal., J Neuroinflammation. 2013 Nov 23;10:139. doi: 10.1186/1742-2094-10-139.
148. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
149. Association between toll-like receptor 4 gene polymorphism and biopsy-proven giant cell arteritis. Palomino-Morales R, etal., J Rheumatol. 2009 Jul;36(7):1501-6. doi: 10.3899/jrheum.081286. Epub 2009 Jun 16.
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151. Myeloid differentiation 2 as a therapeutic target of inflammatory disorders. Park SH, etal., Pharmacol Ther. 2012 Mar;133(3):291-8. doi: 10.1016/j.pharmthera.2011.11.001. Epub 2011 Nov 19.
152. Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis. Pasternak BA, etal., Inflamm Bowel Dis. 2010 May;16(5):856-69. doi: 10.1002/ibd.21132.
153. Common human Toll-like receptor 4 polymorphisms--role in susceptibility to respiratory syncytial virus infection and functional immunological relevance. Paulus SC, etal., Clin Immunol. 2007 Jun;123(3):252-7. Epub 2007 Apr 20.
154. Combined Tlr2 and Tlr4 deficiency increases radiation-induced pulmonary fibrosis in mice. Paun A, etal., Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):1198-205.
155. Deletion of toll-like receptor-4 downregulates protein kinase C-zeta and attenuates liver injury in experimental pancreatitis. Peng Y, etal., Surgery. 2008 May;143(5):679-85. doi: 10.1016/j.surg.2008.01.005.
156. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
157. C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Poggi M, etal., Diabetologia. 2007 Apr 11;.
158. TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid. Prabha C, etal., Immunol Lett. 2008 Apr 15;117(1):26-34. Epub 2007 Dec 3.
159. TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease. Puthothu B, etal., Dis Markers. 2006;22(5-6):303-8.
160. Toll-like receptor expression and activation in mice with experimental dry eye. Redfern RL, etal., Invest Ophthalmol Vis Sci. 2013 Feb 28;54(2):1554-63. doi: 10.1167/iovs.12-10739.
161. Lack of association between polymorphisms of the toll-like receptor 4 gene and cerebral ischemia. Reismann P, etal., J Neurol. 2004 Jul;251(7):853-8.
162. Toll-like receptor 4 signalling pathway activation in a rat model of Acanthamoeba Keratitis. Ren MY and Wu XY, Parasite Immunol. 2011 Jan;33(1):25-33. doi: 10.1111/j.1365-3024.2010.01247.x.
163. Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. Reyna SM, etal., Diabetes. 2008 Oct;57(10):2595-602. Epub 2008 Jul 15.
164. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
165. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
166. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
167. Expression of toll-like receptors 2, 4 and 9 is increased in gingival tissue from patients with type 2 diabetes and chronic periodontitis. Rojo-Botello NR, etal., J Periodontal Res. 2012 Feb;47(1):62-73. doi: 10.1111/j.1600-0765.2011.01405.x. Epub 2011 Aug 17.
168. CD14 C(-159)T polymorphism is a risk factor for development of pulmonary tuberculosis. Rosas-Taraco AG, etal., J Infect Dis. 2007 Dec 1;196(11):1698-706. Epub 2007 Oct 25.
169. Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes. Rudofsky G Jr, etal., Diabetes Care. 2004 Jan;27(1):179-83.
170. Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury. Rusai K, etal., Pediatr Nephrol. 2010 May;25(5):853-60. doi: 10.1007/s00467-009-1422-4. Epub 2010 Feb 4.
171. The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma. Sackesen C, etal., Allergy. 2005 Dec;60(12):1485-92.
172. Single-nucleotide polymorphism of Toll-like receptor 4 and interleukin-10 in response to interferon-based therapy in Egyptian chronic hepatitis C patients. Sadik NA, etal., Arch Virol. 2015 Sep;160(9):2181-95. doi: 10.1007/s00705-015-2493-0. Epub 2015 Jun 23.
173. The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness. Saint Andre Av, etal., Science. 2002 Mar 8;295(5561):1892-5.
174. Innate recognition network driving herpes simplex virus-induced corneal immunopathology: role of the toll pathway in early inflammatory events in stromal keratitis. Sarangi PP, etal., J Virol. 2007 Oct;81(20):11128-38. Epub 2007 Aug 8.
175. The role of TLR4 in photoreceptor {alpha}a crystallin upregulation during early experimental autoimmune uveitis. Saraswathy S, etal., Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3680-6. doi: 10.1167/iovs.09-4575. Epub 2010 Mar 5.
176. Response of macrophage Toll-like receptor 4 to a Sporothrix schenckii lipid extract during experimental sporotrichosis. Sassa MF, etal., Immunology. 2009 Oct;128(2):301-9. doi: 10.1111/j.1365-2567.2009.03118.x.
177. Expression of toll-like receptor 2 and 4 in intestinal mucosa in experimental severe acute pancreatitis. Sawa H, etal., Hepatogastroenterology. 2008 Nov-Dec;55(88):2247-51.
178. Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel. Schmidt M, etal., Nat Immunol. 2010 Sep;11(9):814-9. doi: 10.1038/ni.1919. Epub 2010 Aug 15.
179. Association of polymorphisms of toll-like receptor 4 with a reduced prevalence of hay fever and atopy. Senthilselvan A, etal., Ann Allergy Asthma Immunol. 2008 May;100(5):463-8.
180. Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression. Shah N, etal., J Hepatol. 2012 May;56(5):1047-53. Epub 2012 Jan 17.
181. TLR2 and TLR4 expression in peripheral blood mononuclear cells of patients with chronic cystic echinococcosis and its relationship with IL-10. Shan JY, etal., Parasite Immunol. 2011 Dec;33(12):692-6. doi: 10.1111/j.1365-3024.2011.01335.x.
182. Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice. Sharif R, etal., Gut. 2009 Jun;58(6):813-9. Epub 2009 Feb 6.
183. TLR4 links innate immunity and fatty acid-induced insulin resistance. Shi H, etal., J Clin Invest. 2006 Nov;116(11):3015-25. Epub 2006 Oct 19.
184. Mechanistic investigation of immunosuppression in patients with condyloma acuminata. Shi YJ, etal., Mol Med Rep. 2013 Aug;8(2):480-6. doi: 10.3892/mmr.2013.1511. Epub 2013 Jun 6.
185. Toll-like receptor 4 mediates lung ischemia-reperfusion injury. Shimamoto A, etal., Ann Thorac Surg. 2006 Dec;82(6):2017-23.
186. Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis. Shirai Y, etal., J Gastroenterol Hepatol. 2013 Apr;28(4):723-30. doi: 10.1111/jgh.12112.
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188. Intestinal epithelial barrier dysfunction and dendritic cell redistribution during early stages of inflammation in the rat: role for TLR-2 and -4 blockage. Silva MA, etal., Inflamm Bowel Dis. 2008 May;14(5):632-44.
189. Association of Toll-like receptor 4 polymorphisms with diabetic foot ulcers and application of artificial neural network in DFU risk assessment in type 2 diabetes patients. Singh K, etal., Biomed Res Int. 2013;2013:318686. doi: 10.1155/2013/318686. Epub 2013 Jul 11.
190. TLR4 and TLR9 are induced in oral lichen planus. Siponen M, etal., J Oral Pathol Med. 2012 Nov;41(10):741-7. doi: 10.1111/j.1600-0714.2012.01169.x. Epub 2012 Jun 5.
191. Association of TLR4-T399I polymorphism with chronic obstructive pulmonary disease in smokers. Speletas M, etal., Clin Dev Immunol. 2009;2009:260286. Epub 2010 Feb 15.
192. TLR2 and TLR4 polymorphisms in familial Mediterranean fever. Speletas M, etal., Hum Immunol. 2009 Sep;70(9):750-3. doi: 10.1016/j.humimm.2009.05.004. Epub 2009 May 13.
193. Monocytes from children with clinically stable cystic fibrosis show enhanced expression of Toll-like receptor 4. Sturges NC, etal., Pediatr Pulmonol. 2010 Sep;45(9):883-9.
194. Toll-like receptor 4 gene polymorphisms do not associate with normal tension glaucoma in a Korean population. Suh W, etal., Mol Vis. 2011;17:2343-8. Epub 2011 Aug 31.
195. Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis. Summers SA, etal., Kidney Int. 2010 Sep 15.
196. Biofilm formation and Toll-like receptor 2, Toll-like receptor 4, and NF-kappaB expression in sinus tissues of patients with chronic rhinosinusitis. Sun Y, etal., Am J Rhinol Allergy. 2012 Mar-Apr;26(2):104-9. doi: 10.2500/ajra.2012.26.3718. Epub 2011 Dec 16.
197. A murine model of contact lens-associated fusarium keratitis. Sun Y, etal., Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1511-6. doi: 10.1167/iovs.09-4237. Epub 2009 Oct 29.
198. Association of Toll-like receptor 4 gene polymorphisms in Japanese subjects with primary open-angle, normal-tension, and exfoliation glaucoma. Takano Y, etal., Am J Ophthalmol. 2012 Nov;154(5):825-832.e1. doi: 10.1016/j.ajo.2012.03.050. Epub 2012 Jul 24.
199. Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 4. Takeuchi A, etal., Int Immunopharmacol. 2009 Dec;9(13-14):1562-7. doi: 10.1016/j.intimp.2009.09.012. Epub 2009 Sep 27.
200. Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain. Tanga FY, etal., Neurochem Int 2004 Jul-Aug;45(2-3):397-407.
201. The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy. Tanga FY, etal., Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5856-61. Epub 2005 Apr 4.
202. Effects of antibiotics on expression and function of Toll-like receptors 2 and 4 on mononuclear cells in patients with advanced cirrhosis. Testro AG, etal., J Hepatol. 2010 Feb;52(2):199-205. doi: 10.1016/j.jhep.2009.11.006. Epub 2009 Dec 16.
203. Toll-like receptors gene polymorphisms may confer increased susceptibility to breast cancer development. Theodoropoulos GE, etal., Breast. 2012 Aug;21(4):534-8. doi: 10.1016/j.breast.2012.04.001. Epub 2012 May 2.
204. Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients. Tittarelli A, etal., Cancer Immunol Immunother. 2012 Nov;61(11):2067-77. doi: 10.1007/s00262-012-1268-7. Epub 2012 May 3.
205. Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression. Tu CT, etal., Food Chem Toxicol. 2012 Sep;50(9):3343-51. doi: 10.1016/j.fct.2012.05.050. Epub 2012 Jun 7.
206. Modulation of immune signaling, bacterial clearance, and corneal integrity by toll-like receptors during streptococcus pneumoniae keratitis. Tullos NA, etal., Curr Eye Res. 2013 Oct;38(10):1036-48. doi: 10.3109/02713683.2013.804094. Epub 2013 Jul 10.
207. The expression of TLR2, TLR4 and TLR9 in the epidermis of patients with cutaneous leishmaniasis. Tuon FF, etal., J Dermatol Sci. 2010 Jul;59(1):55-7. doi: 10.1016/j.jdermsci.2010.04.009. Epub 2010 May 20.
208. Synergistic effect of Toll-like receptor 4 and CD14 polymorphisms on the total atherosclerosis burden in patients with peripheral arterial disease. Vainas T, etal., J Vasc Surg. 2006 Aug;44(2):326-32.
209. Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis. van Well GT, etal., PLoS One. 2012;7(5):e35837. doi: 10.1371/journal.pone.0035837. Epub 2012 May 25.
210. Single nucleotide polymorphisms in pathogen recognition receptor genes are associated with susceptibility to meningococcal meningitis in a pediatric cohort. van Well GT, etal., PLoS One. 2013 May 14;8(5):e64252. doi: 10.1371/journal.pone.0064252. Print 2013.
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PMID:27286259   PMID:27290609   PMID:27302095   PMID:27307558   PMID:27310139   PMID:27316642   PMID:27321310   PMID:27323124   PMID:27323819   PMID:27339100   PMID:27340831   PMID:27354597  
PMID:27380627   PMID:27381289   PMID:27418354   PMID:27426724   PMID:27428420   PMID:27442627   PMID:27444640   PMID:27468689   PMID:27486667   PMID:27492306   PMID:27492456   PMID:27495090  
PMID:27526043   PMID:27545207   PMID:27548265   PMID:27551155   PMID:27557632   PMID:27567430   PMID:27569284   PMID:27571579   PMID:27590200   PMID:27590684   PMID:27591966   PMID:27603404  
PMID:27614743   PMID:27615723   PMID:27619660   PMID:27628304   PMID:27636754   PMID:27636999   PMID:27639573   PMID:27649507   PMID:27665434   PMID:27669113   PMID:27669374   PMID:27684822  
PMID:27685627   PMID:27694932   PMID:27714571   PMID:27714813   PMID:27720227   PMID:27744428   PMID:27748869   PMID:27762043   PMID:27769858   PMID:27769864   PMID:27783847   PMID:27793087  
PMID:27793374   PMID:27793853   PMID:27815256   PMID:27837433   PMID:27856281   PMID:27861595   PMID:27878326   PMID:27882497   PMID:27892755   PMID:27895089   PMID:27895422   PMID:27897392  
PMID:27909057   PMID:27909766   PMID:27917620   PMID:27921405   PMID:27925202   PMID:27934908   PMID:27941651   PMID:27943385   PMID:27958344   PMID:27977294   PMID:27981790   PMID:27986871  
PMID:27993530   PMID:27996041   PMID:27997892   PMID:28002812   PMID:28013342   PMID:28013346   PMID:28025440   PMID:28028951   PMID:28058014   PMID:28060792   PMID:28077646   PMID:28083607  
PMID:28089910   PMID:28092654   PMID:28096525   PMID:28210837   PMID:28214954   PMID:28219695   PMID:28220810   PMID:28222760   PMID:28241747   PMID:28241976   PMID:28246611   PMID:28255201  
PMID:28256509   PMID:28256612   PMID:28260877   PMID:28266028   PMID:28272553   PMID:28284355   PMID:28286252   PMID:28296959   PMID:28320058   PMID:28327786   PMID:28330785   PMID:28343193  
PMID:28344199   PMID:28346614   PMID:28347236   PMID:28347875   PMID:28349674   PMID:28359064   PMID:28369600   PMID:28370906   PMID:28386844   PMID:28400700   PMID:28407320   PMID:28407405  
PMID:28411360   PMID:28412855   PMID:28424490   PMID:28427048   PMID:28431986   PMID:28440494   PMID:28463985   PMID:28472619   PMID:28494727   PMID:28497211   PMID:28500692   PMID:28500897  
PMID:28530841   PMID:28531216   PMID:28536249   PMID:28537236   PMID:28537664   PMID:28598999   PMID:28607410   PMID:28609685   PMID:28619997   PMID:28620993   PMID:28623542   PMID:28626766  
PMID:28630139   PMID:28638086   PMID:28653898   PMID:28658622   PMID:28703296   PMID:28733463   PMID:28749716   PMID:28759049   PMID:28765537   PMID:28771725   PMID:28771774   PMID:28776644  
PMID:28793055   PMID:28823914   PMID:28842322   PMID:28844675   PMID:28855621   PMID:28858111   PMID:28858846   PMID:28898406   PMID:28905155   PMID:28930057   PMID:28945461   PMID:28957360  
PMID:28963650   PMID:28965571   PMID:28982115   PMID:28982864   PMID:28987944   PMID:28988039   PMID:28991224   PMID:29020088   PMID:29021606   PMID:29028278   PMID:29030987   PMID:29036538  
PMID:29038465   PMID:29051178   PMID:29055077   PMID:29061842   PMID:29063638   PMID:29066305   PMID:29073942   PMID:29075930   PMID:29085211   PMID:29133417   PMID:29135054   PMID:29136006  
PMID:29136627   PMID:29146546   PMID:29150600   PMID:29150625   PMID:29190778   PMID:29206292   PMID:29227975   PMID:29230705   PMID:29257348   PMID:29276096   PMID:29281684   PMID:29311138  
PMID:29323707   PMID:29324261   PMID:29338742   PMID:29339093   PMID:29343453   PMID:29382328   PMID:29421805   PMID:29440514   PMID:29449625   PMID:29452169   PMID:29472602   PMID:29475090  
PMID:29488617   PMID:29502561   PMID:29521104   PMID:29534643   PMID:29542272   PMID:29543867   PMID:29547441   PMID:29551349   PMID:29553590   PMID:29566186   PMID:29593718   PMID:29593733  
PMID:29602239   PMID:29602972   PMID:29609510   PMID:29649455   PMID:29653364   PMID:29656212   PMID:29663491   PMID:29670828   PMID:29670922   PMID:29681442   PMID:29695002   PMID:29702280  
PMID:29704988   PMID:29728859   PMID:29734352   PMID:29737518   PMID:29740218   PMID:29754966   PMID:29762844   PMID:29762851   PMID:29779787   PMID:29782315   PMID:29804125   PMID:29883450  
PMID:29901164   PMID:29901170   PMID:29916535   PMID:29921378   PMID:29923769   PMID:29924447   PMID:29927028   PMID:29963041   PMID:29968427   PMID:29982285   PMID:29990607   PMID:30013439  
PMID:30015859   PMID:30029898   PMID:30037846   PMID:30042006   PMID:30057921   PMID:30066873   PMID:30071285   PMID:30085081   PMID:30093453   PMID:30098292   PMID:30104241   PMID:30112862  
PMID:30118525   PMID:30124945   PMID:30132861   PMID:30134799   PMID:30138900   PMID:30145468   PMID:30177119   PMID:30204113   PMID:30206272   PMID:30211669   PMID:30220001   PMID:30221732  
PMID:30226538   PMID:30229834   PMID:30233718   PMID:30238832   PMID:30246618   PMID:30273064   PMID:30273982   PMID:30292843   PMID:30299441   PMID:30301709   PMID:30302814   PMID:30309485  
PMID:30321456   PMID:30336978   PMID:30338912   PMID:30341559   PMID:30355052   PMID:30357962   PMID:30365988   PMID:30367515   PMID:30385233   PMID:30403590   PMID:30414341   PMID:30419930  
PMID:30421643   PMID:30463495   PMID:30471852   PMID:30476082   PMID:30497069   PMID:30497388   PMID:30501882   PMID:30512209   PMID:30527625   PMID:30530865   PMID:30536547   PMID:30569830  
PMID:30592973   PMID:30594449   PMID:30626470   PMID:30626473   PMID:30639993   PMID:30649440   PMID:30664982   PMID:30684342   PMID:30710321   PMID:30711948   PMID:30765614   PMID:30771815  
PMID:30776150   PMID:30782639   PMID:30784241   PMID:30785200   PMID:30790400   PMID:30816669   PMID:30824741   PMID:30836660   PMID:30853520   PMID:30857550   PMID:30877182   PMID:30883606  
PMID:30910647   PMID:30915756   PMID:30922233   PMID:30922374   PMID:30924423   PMID:30945288   PMID:30953645   PMID:30954023   PMID:30954991   PMID:30959420   PMID:30972742   PMID:30989725  
PMID:31028612   PMID:31049139   PMID:31065010   PMID:31075178   PMID:31075559   PMID:31081044   PMID:31082340   PMID:31082501   PMID:31083239   PMID:31098402   PMID:31115903   PMID:31153046  
PMID:31153054   PMID:31162913   PMID:31175027   PMID:31180798   PMID:31183391   PMID:31186484   PMID:31190084   PMID:31201585   PMID:31222667   PMID:31238737   PMID:31253871   PMID:31278284  
PMID:31293094   PMID:31304782   PMID:31316302   PMID:31319868   PMID:31328431   PMID:31344401   PMID:31346169   PMID:31357779   PMID:31358689   PMID:31365550   PMID:31382038   PMID:31391207  
PMID:31391320   PMID:31403268   PMID:31407069   PMID:31427442   PMID:31428642   PMID:31456484   PMID:31477211   PMID:31477445   PMID:31484595   PMID:31511519   PMID:31511522   PMID:31515080  
PMID:31530336   PMID:31537875   PMID:31560926   PMID:31561304   PMID:31577725   PMID:31578573   PMID:31586781   PMID:31615295   PMID:31630796   PMID:31640653   PMID:31645185   PMID:31662521  
PMID:31678998   PMID:31690518   PMID:31691860   PMID:31697008   PMID:31705388   PMID:31718931   PMID:31724242   PMID:31732468   PMID:31734268   PMID:31734843   PMID:31739216   PMID:31746424  
PMID:31749314   PMID:31755594   PMID:31759058   PMID:31764760   PMID:31775878   PMID:31785408   PMID:31791577   PMID:31837816   PMID:31843260   PMID:31903617   PMID:31926490   PMID:31936430  
PMID:31952223   PMID:31962161   PMID:31964749   PMID:31977025   PMID:31996057   PMID:32023919   PMID:32026322   PMID:32028672   PMID:32035159   PMID:32050430   PMID:32057259   PMID:32066304  
PMID:32074942   PMID:32097101   PMID:32102594   PMID:32124747   PMID:32146682   PMID:32170544   PMID:32173390   PMID:32173651   PMID:32205424   PMID:32209460   PMID:32221312   PMID:32222425  
PMID:32223496   PMID:32278794   PMID:32281447   PMID:32320335   PMID:32338995   PMID:32345778   PMID:32354122   PMID:32359123   PMID:32378734   PMID:32383269   PMID:32384667   PMID:32388012  
PMID:32391647   PMID:32411792   PMID:32421725   PMID:32424165   PMID:32424768   PMID:32449979   PMID:32468028   PMID:32473847   PMID:32486097   PMID:32494918   PMID:32513051   PMID:32524234  
PMID:32526705   PMID:32552358   PMID:32554157   PMID:32558389   PMID:32579053   PMID:32606656   PMID:32615574   PMID:32648572   PMID:32650475   PMID:32674360   PMID:32702524   PMID:32708841  
PMID:32739154   PMID:32740454   PMID:32753695   PMID:32755994   PMID:32764765   PMID:32790017   PMID:32799375   PMID:32799786   PMID:32800556   PMID:32802180   PMID:32808884   PMID:32822099  
PMID:32822111   PMID:32827217   PMID:32842834   PMID:32844696   PMID:32852789   PMID:32862585   PMID:32863955   PMID:32871478   PMID:32914185   PMID:32929325   PMID:32930944   PMID:32931797  
PMID:32950783   PMID:32961144   PMID:32967147   PMID:32988728   PMID:32989935   PMID:33007372   PMID:33040333   PMID:33046755   PMID:33052227   PMID:33053215   PMID:33057840   PMID:33072072  
PMID:33073533   PMID:33073966   PMID:33079297   PMID:33114004   PMID:33138336   PMID:33148838   PMID:33195243   PMID:33199767   PMID:33216117   PMID:33247673   PMID:33255670   PMID:33276244  
PMID:33318565   PMID:33324395   PMID:33355374   PMID:33356682   PMID:33369094   PMID:33383282   PMID:33386789   PMID:33396586   PMID:33426065   PMID:33436266   PMID:33446670   PMID:33446690  
PMID:33476981   PMID:33481008   PMID:33505220   PMID:33512337   PMID:33512737   PMID:33516663   PMID:33528653   PMID:33556340   PMID:33570702   PMID:33576548   PMID:33581132   PMID:33589625  
PMID:33627146   PMID:33649824   PMID:33692011   PMID:33724604   PMID:33731807   PMID:33742149   PMID:33755965   PMID:33776924   PMID:33868293   PMID:33903586   PMID:33910419   PMID:33932524  
PMID:33938125   PMID:33939072   PMID:33955317   PMID:33962830   PMID:33982771   PMID:33991642   PMID:34021857   PMID:34022297   PMID:34068701   PMID:34091792   PMID:34093588   PMID:34099337  
PMID:34110366   PMID:34119822   PMID:34149728   PMID:34192627   PMID:34206009   PMID:34215697   PMID:34216140   PMID:34226490   PMID:34234778   PMID:34279173   PMID:34282358   PMID:34287094  
PMID:34307192   PMID:34334784   PMID:34339079   PMID:34341172   PMID:34378353   PMID:34385421   PMID:34416273   PMID:34420402   PMID:34463846   PMID:34479599   PMID:34544967   PMID:34550727  
PMID:34588497   PMID:34605740   PMID:34609157   PMID:34626426   PMID:34651657   PMID:34655744   PMID:34657898   PMID:34710721   PMID:34718133   PMID:34746034   PMID:34780278   PMID:34814947  
PMID:34829995   PMID:34844429   PMID:34882370   PMID:34884442   PMID:34893207   PMID:34928049   PMID:34982175   PMID:35020096   PMID:35034101   PMID:35049137   PMID:35113284   PMID:35120922  
PMID:35128637   PMID:35140704   PMID:35158151   PMID:35171542   PMID:35278458   PMID:35294925   PMID:35325354   PMID:35327577   PMID:35343654   PMID:35345353   PMID:35349724   PMID:35369030  
PMID:35396219   PMID:35404176   PMID:35432371   PMID:35434747   PMID:35434749   PMID:35459439   PMID:35459853   PMID:35463988   PMID:35468924   PMID:35500224   PMID:35577786   PMID:35612375  
PMID:35618937   PMID:35667541   PMID:35690624   PMID:35720418   PMID:35757501   PMID:35767946   PMID:35779195   PMID:35798718   PMID:35812397   PMID:35815676   PMID:35832490   PMID:35855659  
PMID:35897640   PMID:35910856   PMID:35955552   PMID:35993243   PMID:35994955   PMID:36008864   PMID:36012696   PMID:36052709   PMID:36102304   PMID:36135817   PMID:36142893   PMID:36158875  
PMID:36164994   PMID:36165200   PMID:36165427   PMID:36203339   PMID:36230982   PMID:36231099   PMID:36232715   PMID:36233127   PMID:36240653   PMID:36260448   PMID:36264772   PMID:36401285  
PMID:36454439   PMID:36462956   PMID:36463168   PMID:36464762   PMID:36495029   PMID:36563560   PMID:36585554   PMID:36586092   PMID:36591765   PMID:36636919   PMID:36648243   PMID:36654387  
PMID:36658449   PMID:36674930   PMID:36717005   PMID:36719505   PMID:36736217   PMID:36827055   PMID:36857178   PMID:36890438   PMID:36915050   PMID:36926756   PMID:36978183   PMID:37075527  
PMID:37085277   PMID:37097031   PMID:37102696   PMID:37115397   PMID:37150251   PMID:37150813   PMID:37178812   PMID:37187734   PMID:37231959   PMID:37239362   PMID:37257791   PMID:37272109  
PMID:37287037   PMID:37330637   PMID:37396730   PMID:37408202   PMID:37459905   PMID:37462743   PMID:37468052   PMID:37511459   PMID:37554278   PMID:37567009   PMID:37571378   PMID:37578655  
PMID:37580395   PMID:37605037   PMID:37671668   PMID:37686069   PMID:37691112   PMID:37718198   PMID:37733613   PMID:37773690   PMID:37828881   PMID:37830554   PMID:37844099   PMID:37846082  
PMID:37849336   PMID:37876569   PMID:37885279   PMID:37904102   PMID:37937521   PMID:37977066   PMID:37994415   PMID:38007427   PMID:38029833   PMID:38103365   PMID:38157380   PMID:38195088  
PMID:38240248   PMID:38280480   PMID:38287815   PMID:38367924   PMID:38415550   PMID:38431805   PMID:38433829   PMID:38500425   PMID:38558098   PMID:38567476   PMID:38577560   PMID:38585277  


Genomics

Comparative Map Data
TLR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389117,704,403 - 117,724,735 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9117,704,175 - 117,724,735 (+)EnsemblGRCh38hg38GRCh38
GRCh379120,466,681 - 120,487,013 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369119,506,431 - 119,519,589 (+)NCBINCBI36Build 36hg18NCBI36
Build 349117,546,137 - 117,556,781NCBI
Celera991,114,228 - 91,127,535 (+)NCBICelera
Cytogenetic Map9q33.1NCBI
HuRef990,084,535 - 90,097,850 (+)NCBIHuRef
CHM1_19120,614,005 - 120,627,323 (+)NCBICHM1_1
T2T-CHM13v2.09129,898,286 - 129,918,621 (+)NCBIT2T-CHM13v2.0
Tlr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39466,745,788 - 66,765,338 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl466,745,821 - 66,848,521 (+)EnsemblGRCm39 Ensembl
GRCm38466,827,551 - 66,846,581 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl466,827,584 - 66,930,284 (+)EnsemblGRCm38mm10GRCm38
MGSCv37466,488,845 - 66,503,831 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36466,314,172 - 66,329,158 (+)NCBIMGSCv36mm8
Celera465,431,141 - 65,446,127 (+)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.66NCBI
Tlr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8585,161,247 - 85,174,882 (+)NCBIGRCr8
mRatBN7.2580,145,867 - 80,159,501 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl580,145,826 - 80,159,628 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx582,524,918 - 82,538,532 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0584,342,217 - 84,355,831 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0584,317,856 - 84,331,470 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0582,587,424 - 82,601,056 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl582,587,420 - 82,601,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0586,690,670 - 86,704,302 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4583,564,100 - 83,577,735 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1583,569,212 - 83,582,848 (+)NCBI
Celera579,045,293 - 79,058,928 (+)NCBICelera
RH 3.4 Map5643.7RGD
Cytogenetic Map5q24NCBI
Tlr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541910,191,120 - 10,202,135 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541910,190,937 - 10,201,896 (-)NCBIChiLan1.0ChiLan1.0
TLR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21121,637,696 - 21,650,558 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1921,630,343 - 21,652,922 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0988,827,495 - 88,840,458 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19117,180,250 - 117,193,510 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9117,180,550 - 117,190,711 (+)Ensemblpanpan1.1panPan2
TLR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11171,356,390 - 71,367,166 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1171,356,390 - 71,367,165 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1169,768,502 - 69,779,281 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01172,483,514 - 72,494,289 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1172,483,210 - 72,494,579 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11171,012,889 - 71,023,665 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01171,034,981 - 71,045,756 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01171,767,611 - 71,778,394 (+)NCBIUU_Cfam_GSD_1.0
Tlr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947186,750,688 - 186,763,650 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364876,518,441 - 6,533,095 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364876,519,140 - 6,532,018 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1258,044,610 - 258,058,970 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11258,044,610 - 258,054,641 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21289,775,816 - 289,785,847 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TLR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11221,873,762 - 21,885,562 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1221,871,773 - 21,885,515 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603521,002,852 - 21,019,229 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tlr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476017,598,630 - 17,609,120 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476017,596,516 - 17,608,955 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TLR4
50 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_138554.5(TLR4):c.1779G>A (p.Trp593Ter) single nucleotide variant not provided [RCV001725884] Chr9:117713907 [GRCh38]
Chr9:120476185 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.896A>G (p.Asp299Gly) single nucleotide variant COPD, severe early onset [RCV003390649]|Pericementitis [RCV001729340]|Susceptibility to severe coronavirus disease (COVID-19) [RCV003231092]|TLR4 POLYMORPHISM [RCV000007040] Chr9:117713024 [GRCh38]
Chr9:120475302 [GRCh37]
Chr9:9q33.1		 pathogenic|risk factor|likely risk allele|benign|protective|uncertain significance
NM_138554.5(TLR4):c.1196C>T (p.Thr399Ile) single nucleotide variant COPD, severe early onset [RCV003390650]|TLR4 POLYMORPHISM [RCV000007043]|not provided [RCV000086999] Chr9:117713324 [GRCh38]
Chr9:120475602 [GRCh37]
Chr9:9q33.1		 pathogenic|benign|uncertain significance|not provided
GRCh38/hg38 9q33.1(chr9:117189877-119261350)x3 copy number gain See cases [RCV000050343] Chr9:117189877..119261350 [GRCh38]
Chr9:119952156..122023628 [GRCh37]
Chr9:118991977..121063449 [NCBI36]
Chr9:9q33.1		 uncertain significance
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000050348] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124532)x3 copy number gain See cases [RCV000053745] Chr9:193412..138124532 [GRCh38]
Chr9:204193..141018984 [GRCh37]
Chr9:194193..140138805 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|See cases [RCV000053748] Chr9:193412..138179445 [GRCh38]
Chr9:266045..141073897 [GRCh37]
Chr9:256045..140193718 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138114463)x3 copy number gain See cases [RCV000053746] Chr9:193412..138114463 [GRCh38]
Chr9:214367..141008915 [GRCh37]
Chr9:204367..140128736 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
NM_138554.4(TLR4):c.720A>G (p.Leu240=) single nucleotide variant Malignant melanoma [RCV000068513] Chr9:117712848 [GRCh38]
Chr9:120475126 [GRCh37]
Chr9:119514947 [NCBI36]
Chr9:9q33.1		 not provided
NM_138554.4(TLR4):c.866G>A (p.Arg289Gln) single nucleotide variant Malignant melanoma [RCV000068514] Chr9:117712994 [GRCh38]
Chr9:120475272 [GRCh37]
Chr9:119515093 [NCBI36]
Chr9:9q33.1		 not provided
NM_138554.4(TLR4):c.2110C>T (p.Gln704Ter) single nucleotide variant Malignant melanoma [RCV000068515] Chr9:117714238 [GRCh38]
Chr9:120476516 [GRCh37]
Chr9:119516337 [NCBI36]
Chr9:9q33.1		 not provided
NM_138554.4(TLR4):c.1057C>T (p.Leu353Phe) single nucleotide variant Malignant melanoma [RCV000061876] Chr9:117713185 [GRCh38]
Chr9:120475463 [GRCh37]
Chr9:119515284 [NCBI36]
Chr9:9q33.1		 not provided
NM_138554.4(TLR4):c.261-240C>T single nucleotide variant Lung cancer [RCV000108088] Chr9:117712149 [GRCh38]
Chr9:120474427 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.842G>A (p.Cys281Tyr) single nucleotide variant not provided [RCV000087000] Chr9:117712970 [GRCh38]
Chr9:120475248 [GRCh37]
Chr9:9q33.1		 not provided
GRCh38/hg38 9p24.3-q34.3(chr9:204193-138179445) copy number gain See cases [RCV000133791] Chr9:204193..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9q33.1(chr9:117132868-119269252)x3 copy number gain See cases [RCV000137303] Chr9:117132868..119269252 [GRCh38]
Chr9:119895147..122031530 [GRCh37]
Chr9:118934968..121071351 [NCBI36]
Chr9:9q33.1		 likely benign
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124524)x3 copy number gain See cases [RCV000138783] Chr9:193412..138124524 [GRCh38]
Chr9:204090..141018976 [GRCh37]
Chr9:194090..140138797 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9p11.2-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000139207] Chr9:193412..138159073 [GRCh38]
Chr9:68420641..141053525 [GRCh37]
Chr9:67910461..140173346 [NCBI36]
Chr9:9p11.2-q34.3		 pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000138962] Chr9:193412..138159073 [GRCh38]
Chr9:204104..141053525 [GRCh37]
Chr9:194104..140173346 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic|conflicting data from submitters
GRCh38/hg38 9q31.2-33.1(chr9:107530314-117965944)x1 copy number loss See cases [RCV000140794] Chr9:107530314..117965944 [GRCh38]
Chr9:110292595..120728222 [GRCh37]
Chr9:109332416..119768043 [NCBI36]
Chr9:9q31.2-33.1		 pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:203861-138125937)x3 copy number gain See cases [RCV000141876] Chr9:203861..138125937 [GRCh38]
Chr9:203861..141020389 [GRCh37]
Chr9:193861..140140210 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9q33.1(chr9:117027717-119196572)x3 copy number gain See cases [RCV000141541] Chr9:117027717..119196572 [GRCh38]
Chr9:119789996..121958850 [GRCh37]
Chr9:118829817..120998671 [NCBI36]
Chr9:9q33.1		 uncertain significance
GRCh38/hg38 9p24.3-q34.3(chr9:203862-138125937)x3 copy number gain See cases [RCV000143476] Chr9:203862..138125937 [GRCh38]
Chr9:203862..141020389 [GRCh37]
Chr9:193862..140140210 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000148113] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3		 pathogenic
GRCh38/hg38 9q33.1(chr9:117189877-119261350)x3 copy number gain See cases [RCV000148174] Chr9:117189877..119261350 [GRCh38]
Chr9:119952156..122023628 [GRCh37]
Chr9:118991977..121063449 [NCBI36]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9p24.3-q34.3(chr9:163131-141122114)x3 copy number gain See cases [RCV000240081] Chr9:163131..141122114 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:62525-141006407) copy number gain See cases [RCV000449375] Chr9:62525..141006407 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020389)x3 copy number gain not specified [RCV003986800] Chr9:203861..141020389 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203864-141020389)x3 copy number gain See cases [RCV000448978] Chr9:203864..141020389 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9q31.1-33.3(chr9:104604851-126253089)x1 copy number loss See cases [RCV000447763] Chr9:104604851..126253089 [GRCh37]
Chr9:9q31.1-33.3		 pathogenic
GRCh37/hg19 9q33.1(chr9:119924832-122047582)x3 copy number gain See cases [RCV000447689] Chr9:119924832..122047582 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:118602947-121246861)x1 copy number loss See cases [RCV000511914] Chr9:118602947..121246861 [GRCh37]
Chr9:9q33.1		 likely pathogenic
GRCh37/hg19 9q31.3-33.2(chr9:114299780-123267736)x1 copy number loss See cases [RCV000511049] Chr9:114299780..123267736 [GRCh37]
Chr9:9q31.3-33.2		 pathogenic
GRCh37/hg19 9q21.11-34.3(chr9:71069743-140999928) copy number gain Global developmental delay [RCV000626548] Chr9:71069743..140999928 [GRCh37]
Chr9:9q21.11-34.3		 likely pathogenic
NM_138554.5(TLR4):c.901A>G (p.Ile301Val) single nucleotide variant Inborn genetic diseases [RCV003277601] Chr9:117713029 [GRCh38]
Chr9:120475307 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9p24.3-q34.3(chr9:203862-141020389) copy number gain See cases [RCV000512392] Chr9:203862..141020389 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9q33.1(chr9:120063442-121802501)x3 copy number gain not provided [RCV000683157] Chr9:120063442..121802501 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141114095)x2 copy number gain not provided [RCV000748054] Chr9:10590..141114095 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9q31.3-33.3(chr9:113083182-126779494)x1 copy number loss not provided [RCV000748606] Chr9:113083182..126779494 [GRCh37]
Chr9:9q31.3-33.3		 pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141122247)x3 copy number gain not provided [RCV000748055] Chr9:10590..141122247 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141107672)x3 copy number gain not provided [RCV000748053] Chr9:10590..141107672 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:46587-141066491)x3 copy number gain not provided [RCV000748063] Chr9:46587..141066491 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
NM_138554.5(TLR4):c.2288G>A (p.Arg763His) single nucleotide variant not provided [RCV001702261] Chr9:117714416 [GRCh38]
Chr9:120476694 [GRCh37]
Chr9:9q33.1		 likely benign
NM_138554.5(TLR4):c.1635C>T (p.Ser545=) single nucleotide variant not provided [RCV000944642] Chr9:117713763 [GRCh38]
Chr9:120476041 [GRCh37]
Chr9:9q33.1		 likely benign
NM_138554.5(TLR4):c.1959G>A (p.Lys653=) single nucleotide variant not provided [RCV000968942] Chr9:117714087 [GRCh38]
Chr9:120476365 [GRCh37]
Chr9:9q33.1		 benign
NM_138554.5(TLR4):c.435C>A (p.Pro145=) single nucleotide variant TLR4-related condition [RCV003918423]|not provided [RCV000969998] Chr9:117712563 [GRCh38]
Chr9:120474841 [GRCh37]
Chr9:9q33.1		 benign|likely benign
NM_138554.5(TLR4):c.339C>T (p.Pro113=) single nucleotide variant not provided [RCV000915125] Chr9:117712467 [GRCh38]
Chr9:120474745 [GRCh37]
Chr9:9q33.1		 benign
NM_138554.5(TLR4):c.1521A>G (p.Gln507=) single nucleotide variant not provided [RCV000931946] Chr9:117713649 [GRCh38]
Chr9:120475927 [GRCh37]
Chr9:9q33.1		 likely benign
NM_138554.5(TLR4):c.1062A>G (p.Lys354=) single nucleotide variant not provided [RCV000960266] Chr9:117713190 [GRCh38]
Chr9:120475468 [GRCh37]
Chr9:9q33.1		 benign|likely benign
GRCh37/hg19 9q33.1(chr9:119501624-120870515)x3 copy number gain not provided [RCV000848554] Chr9:119501624..120870515 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:119924909-122047532)x3 copy number gain not provided [RCV000848237] Chr9:119924909..122047532 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q21.11-34.3(chr9:71416475-141020389)x3 copy number gain not provided [RCV000847808] Chr9:71416475..141020389 [GRCh37]
Chr9:9q21.11-34.3		 pathogenic
GRCh37/hg19 9q33.1(chr9:120400158-122016593)x3 copy number gain not provided [RCV000848161] Chr9:120400158..122016593 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:119920495-122047532)x3 copy number gain not provided [RCV000846008] Chr9:119920495..122047532 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020388)x3 copy number gain not provided [RCV000845900] Chr9:203861..141020388 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
NM_138554.5(TLR4):c.1329C>T (p.Phe443=) single nucleotide variant not provided [RCV000886025] Chr9:117713457 [GRCh38]
Chr9:120475735 [GRCh37]
Chr9:9q33.1		 likely benign
NM_138554.5(TLR4):c.489A>G (p.Gln163=) single nucleotide variant not provided [RCV000890778] Chr9:117712617 [GRCh38]
Chr9:120474895 [GRCh37]
Chr9:9q33.1		 benign
NM_138554.5(TLR4):c.2474G>A (p.Gly825Glu) single nucleotide variant Hereditary angioedema with normal C1Inh [RCV001027422] Chr9:117714602 [GRCh38]
Chr9:120476880 [GRCh37]
Chr9:9q33.1		 not provided
NM_138554.5(TLR4):c.2308G>A (p.Val770Ile) single nucleotide variant not provided [RCV001357293] Chr9:117714436 [GRCh38]
Chr9:120476714 [GRCh37]
Chr9:9q33.1		 uncertain significance
NC_000009.12:g.117724891CA[28] microsatellite not provided [RCV001356600] Chr9:117724889..117724890 [GRCh38]
Chr9:120487167..120487168 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.*2010G>C single nucleotide variant not provided [RCV001687972] Chr9:117716658 [GRCh38]
Chr9:120478936 [GRCh37]
Chr9:9q33.1		 benign
GRCh37/hg19 9q33.1-33.2(chr9:117853848-124633077)x1 copy number loss Delayed speech and language development [RCV001801196] Chr9:117853848..124633077 [GRCh37]
Chr9:9q33.1-33.2		 uncertain significance
GRCh37/hg19 9q31.1-33.3(chr9:104604851-126253089) copy number loss not specified [RCV002052825] Chr9:104604851..126253089 [GRCh37]
Chr9:9q31.1-33.3		 pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:353349-141020389) copy number gain not specified [RCV002053823] Chr9:353349..141020389 [GRCh37]
Chr9:9p24.3-q34.3		 pathogenic
GRCh37/hg19 9q33.1(chr9:119722551-121219732) copy number gain not specified [RCV002052843] Chr9:119722551..121219732 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q32-34.11(chr9:116422275-131713233) copy number gain not specified [RCV002052831] Chr9:116422275..131713233 [GRCh37]
Chr9:9q32-34.11		 pathogenic
GRCh37/hg19 9q21.11-33.2(chr9:71349994-122603410) copy number gain not specified [RCV002053853] Chr9:71349994..122603410 [GRCh37]
Chr9:9q21.11-33.2		 likely pathogenic
GRCh37/hg19 9q33.1-33.3(chr9:120045175-127335905)x1 copy number loss not provided [RCV001834516] Chr9:120045175..127335905 [GRCh37]
Chr9:9q33.1-33.3		 pathogenic
NM_138554.5(TLR4):c.526_544del (p.Asn176fs) deletion Susceptibility to severe COVID-19 [RCV003120839]|not specified [RCV002223166] Chr9:117712650..117712668 [GRCh38]
Chr9:120474928..120474946 [GRCh37]
Chr9:9q33.1		 likely risk allele|uncertain significance
NM_138554.5(TLR4):c.*455G>A single nucleotide variant Lung adenocarcinoma [RCV003129602] Chr9:117715103 [GRCh38]
Chr9:120477381 [GRCh37]
Chr9:9q33.1		 likely benign
GRCh37/hg19 9p24.3-q34.11(chr9:203861-131603223)x3 copy number gain See cases [RCV002292402] Chr9:203861..131603223 [GRCh37]
Chr9:9p24.3-q34.11		 pathogenic
NM_138554.5(TLR4):c.1431A>T (p.Lys477Asn) single nucleotide variant Lung adenocarcinoma [RCV003129696] Chr9:117713559 [GRCh38]
Chr9:120475837 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.925A>T (p.Asn309Tyr) single nucleotide variant Inborn genetic diseases [RCV002752118] Chr9:117713053 [GRCh38]
Chr9:120475331 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.826G>T (p.Ala276Ser) single nucleotide variant Inborn genetic diseases [RCV002690001] Chr9:117712954 [GRCh38]
Chr9:120475232 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1688A>G (p.Glu563Gly) single nucleotide variant Inborn genetic diseases [RCV002883240] Chr9:117713816 [GRCh38]
Chr9:120476094 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1128G>T (p.Glu376Asp) single nucleotide variant Inborn genetic diseases [RCV002902024] Chr9:117713256 [GRCh38]
Chr9:120475534 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.64A>G (p.Arg22Gly) single nucleotide variant Inborn genetic diseases [RCV002973802] Chr9:117704536 [GRCh38]
Chr9:120466814 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:120197413-120521544)x3 copy number gain not provided [RCV002475840] Chr9:120197413..120521544 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.175C>G (p.Leu59Val) single nucleotide variant Inborn genetic diseases [RCV002759509] Chr9:117708644 [GRCh38]
Chr9:120470922 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.2046C>A (p.Ser682Arg) single nucleotide variant Inborn genetic diseases [RCV002870537] Chr9:117714174 [GRCh38]
Chr9:120476452 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1017C>A (p.Asn339Lys) single nucleotide variant Inborn genetic diseases [RCV002910312] Chr9:117713145 [GRCh38]
Chr9:120475423 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.2348T>C (p.Val783Ala) single nucleotide variant Inborn genetic diseases [RCV002804105] Chr9:117714476 [GRCh38]
Chr9:120476754 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.61G>A (p.Val21Met) single nucleotide variant Inborn genetic diseases [RCV002789502] Chr9:117704533 [GRCh38]
Chr9:120466811 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1015A>G (p.Asn339Asp) single nucleotide variant Inborn genetic diseases [RCV002788807] Chr9:117713143 [GRCh38]
Chr9:120475421 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1955A>G (p.Tyr652Cys) single nucleotide variant Inborn genetic diseases [RCV002920631] Chr9:117714083 [GRCh38]
Chr9:120476361 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.*6290C>A single nucleotide variant Squamous cell carcinoma [RCV003129683] Chr9:117720938 [GRCh38]
Chr9:120483216 [GRCh37]
Chr9:9q33.1		 likely benign
NM_138554.5(TLR4):c.*4092C>T single nucleotide variant Lung adenocarcinoma [RCV003129717] Chr9:117718740 [GRCh38]
Chr9:120481018 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.6G>T (p.Met2Ile) single nucleotide variant Lung adenocarcinoma [RCV003129691] Chr9:117704478 [GRCh38]
Chr9:120466756 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1676C>T (p.Ser559Phe) single nucleotide variant Inborn genetic diseases [RCV003203038] Chr9:117713804 [GRCh38]
Chr9:120476082 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.557A>G (p.Lys186Arg) single nucleotide variant Inborn genetic diseases [RCV003217954] Chr9:117712685 [GRCh38]
Chr9:120474963 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1855C>T (p.Pro619Ser) single nucleotide variant Inborn genetic diseases [RCV003261635] Chr9:117713983 [GRCh38]
Chr9:120476261 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.22G>T (p.Ala8Ser) single nucleotide variant Inborn genetic diseases [RCV003376290] Chr9:117704494 [GRCh38]
Chr9:120466772 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.436A>G (p.Ile146Val) single nucleotide variant Inborn genetic diseases [RCV003352633] Chr9:117712564 [GRCh38]
Chr9:120474842 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1093A>G (p.Asn365Asp) single nucleotide variant Inborn genetic diseases [RCV003354838] Chr9:117713221 [GRCh38]
Chr9:120475499 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:119347611-122171551)x3 copy number gain not provided [RCV003484780] Chr9:119347611..122171551 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:119924833-122047532)x3 copy number gain not provided [RCV003484781] Chr9:119924833..122047532 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:120399944-122017413)x3 copy number gain not provided [RCV003484783] Chr9:120399944..122017413 [GRCh37]
Chr9:9q33.1		 uncertain significance
GRCh37/hg19 9q33.1(chr9:119920495-122047673)x3 copy number gain not specified [RCV003986816] Chr9:119920495..122047673 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.277A>G (p.Ile93Val) single nucleotide variant TLR4-related condition [RCV003952013] Chr9:117712405 [GRCh38]
Chr9:120474683 [GRCh37]
Chr9:9q33.1		 likely benign
NM_138554.5(TLR4):c.1899C>A (p.Ile633=) single nucleotide variant TLR4-related condition [RCV003931496] Chr9:117714027 [GRCh38]
Chr9:120476305 [GRCh37]
Chr9:9q33.1		 likely benign
NM_138554.5(TLR4):c.523A>G (p.Thr175Ala) single nucleotide variant TLR4-related condition [RCV003911545] Chr9:117712651 [GRCh38]
Chr9:120474929 [GRCh37]
Chr9:9q33.1		 likely benign
GRCh37/hg19 9q33.1(chr9:119278687-121653529)x3 copy number gain not provided [RCV003885522] Chr9:119278687..121653529 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1366C>T (p.His456Tyr) single nucleotide variant not provided [RCV003884096] Chr9:117713494 [GRCh38]
Chr9:120475772 [GRCh37]
Chr9:9q33.1		 uncertain significance
NM_138554.5(TLR4):c.1530G>T (p.Gln510His) single nucleotide variant TLR4-related condition [RCV003914585] Chr9:117713658 [GRCh38]
Chr9:120475936 [GRCh37]
Chr9:9q33.1		 benign
NM_138554.5(TLR4):c.219C>G (p.Ser73Arg) single nucleotide variant TLR4-related condition [RCV003976703] Chr9:117708688 [GRCh38]
Chr9:120470966 [GRCh37]
Chr9:9q33.1		 benign
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR146Ahsa-miR-146a-5pMirtarbaseexternal_infoELISA//Luciferase reporter assay//Microarray//qRT-Functional MTI21329689
MIRLET7Ihsa-let-7i-5pMirecordsexternal_info{unchanged}{unchanged}NA17660297
MIRLET7Ihsa-let-7i-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI17660297

Predicted Target Of
Summary Value
Count of predictions:1325
Count of miRNA genes:624
Interacting mature miRNAs:696
Transcripts:ENST00000355622, ENST00000394487, ENST00000472304, ENST00000490685
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D9S1060E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,477,406 - 120,477,499UniSTSGRCh37
Build 369119,517,227 - 119,517,320RGDNCBI36
Celera991,125,173 - 91,125,266RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,095,487 - 90,095,580UniSTS
PMC128073P5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,475,141 - 120,475,576UniSTSGRCh37
Build 369119,514,962 - 119,515,397RGDNCBI36
Celera991,122,908 - 91,123,343RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,093,222 - 90,093,657UniSTS
PMC201071P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,574 - 120,476,680UniSTSGRCh37
Build 369119,516,395 - 119,516,501RGDNCBI36
Celera991,124,341 - 91,124,447RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,094,655 - 90,094,761UniSTS
PMC201071P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,606 - 120,476,680UniSTSGRCh37
Build 369119,516,427 - 119,516,501RGDNCBI36
Celera991,124,373 - 91,124,447RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,094,687 - 90,094,761UniSTS
PMC289161P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,474,990 - 120,475,402UniSTSGRCh37
Build 369119,514,811 - 119,515,223RGDNCBI36
Celera991,122,757 - 91,123,169RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,093,071 - 90,093,483UniSTS
PMC31919P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,474,611 - 120,474,941UniSTSGRCh37
Build 369119,514,432 - 119,514,762RGDNCBI36
Celera991,122,378 - 91,122,708RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,092,692 - 90,093,022UniSTS
PMC55404P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,474,790 - 120,475,080UniSTSGRCh37
Build 369119,514,611 - 119,514,901RGDNCBI36
Celera991,122,557 - 91,122,847RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,092,871 - 90,093,161UniSTS
PMC97668P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,039 - 120,476,533UniSTSGRCh37
Build 369119,515,860 - 119,516,354RGDNCBI36
Celera991,123,806 - 91,124,300RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,094,120 - 90,094,614UniSTS
PMC98129P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,010 - 120,476,516UniSTSGRCh37
Build 369119,515,831 - 119,516,337RGDNCBI36
Celera991,123,777 - 91,124,283RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,094,091 - 90,094,597UniSTS
PMC98226P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,010 - 120,476,516UniSTSGRCh37
Build 369119,515,831 - 119,516,337RGDNCBI36
Celera991,123,777 - 91,124,283RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,094,091 - 90,094,597UniSTS
PMC98510P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,374 - 120,476,838UniSTSGRCh37
Build 369119,516,195 - 119,516,659RGDNCBI36
Celera991,124,141 - 91,124,605RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,094,455 - 90,094,919UniSTS
PMC98826P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,209 - 120,476,805UniSTSGRCh37
Build 369119,516,030 - 119,516,626RGDNCBI36
Celera991,123,976 - 91,124,572RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,094,290 - 90,094,886UniSTS
TLR4_1086  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,477,257 - 120,478,067UniSTSGRCh37
Build 369119,517,078 - 119,517,888RGDNCBI36
Celera991,125,024 - 91,125,834RGD
HuRef990,095,338 - 90,096,148UniSTS
A009X32  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,477,457 - 120,477,604UniSTSGRCh37
Build 369119,517,278 - 119,517,425RGDNCBI36
Celera991,125,224 - 91,125,371RGD
Cytogenetic Map9q33.1UniSTS
HuRef990,095,538 - 90,095,685UniSTS
GeneMap99-GB4 RH Map9365.02UniSTS
TLR4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,476,680 - 120,476,851UniSTSGRCh37
Build 369119,516,501 - 119,516,672RGDNCBI36
Celera991,124,447 - 91,124,618RGD
HuRef990,094,761 - 90,094,932UniSTS
G32954  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379120,477,457 - 120,477,604UniSTSGRCh37
Celera991,125,224 - 91,125,371UniSTS
Cytogenetic Map9q33.1UniSTS
HuRef990,095,538 - 90,095,685UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 400 1396 573 118 1055 62 1338 242 619 146 239 1022 58 1171 559 2
Low 1971 1588 1128 490 501 387 2889 1923 3076 260 1151 459 109 1 33 2229 1
Below cutoff 24 2 12 8 268 9 92 6 15 6 28 49 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_011475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA598398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB445638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF177765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF177766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK226155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL160272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL710219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG622357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA126770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA187988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA218006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ018107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ018108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ018109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ018110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF535829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF535830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF535831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF535832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF535833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FB700885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GM869034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ903698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ903699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ903700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ903701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ903702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU071276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU143427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ480999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ481241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC580434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC580435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC624801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC712875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC720992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG385628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT672268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OP720910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OP720911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OR924455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OR924456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U69193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U93091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000355622   ⟹   ENSP00000363089
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl9117,704,403 - 117,724,735 (+)Ensembl
RefSeq Acc Id: ENST00000394487   ⟹   ENSP00000377997
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl9117,704,192 - 117,715,775 (+)Ensembl
RefSeq Acc Id: ENST00000472304   ⟹   ENSP00000496429
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl9117,704,175 - 117,714,952 (+)Ensembl
RefSeq Acc Id: ENST00000490685
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl9117,708,197 - 117,708,979 (+)Ensembl
RefSeq Acc Id: NM_003266   ⟹   NP_003257
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389117,704,403 - 117,724,735 (+)NCBI
HuRef990,084,535 - 90,097,850 (+)NCBI
CHM1_19120,614,005 - 120,627,323 (+)NCBI
T2T-CHM13v2.09129,898,286 - 129,918,621 (+)NCBI
Sequence:
RefSeq Acc Id: NM_138554   ⟹   NP_612564
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389117,704,403 - 117,724,735 (+)NCBI
GRCh379120,466,453 - 120,479,769 (+)NCBI
Build 369119,506,431 - 119,519,589 (+)NCBI Archive
HuRef990,084,535 - 90,097,850 (+)NCBI
CHM1_19120,614,005 - 120,627,323 (+)NCBI
T2T-CHM13v2.09129,898,286 - 129,918,621 (+)NCBI
Sequence:
RefSeq Acc Id: NM_138557   ⟹   NP_612567
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389117,704,403 - 117,724,735 (+)NCBI
HuRef990,084,535 - 90,097,850 (+)NCBI
CHM1_19120,614,005 - 120,627,323 (+)NCBI
T2T-CHM13v2.09129,898,286 - 129,918,621 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_003257 (Get FASTA)   NCBI Sequence Viewer  
  NP_612564 (Get FASTA)   NCBI Sequence Viewer  
  NP_612567 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC34135 (Get FASTA)   NCBI Sequence Viewer  
  AAC80227 (Get FASTA)   NCBI Sequence Viewer  
  AAF05316 (Get FASTA)   NCBI Sequence Viewer  
  AAF07823 (Get FASTA)   NCBI Sequence Viewer  
  AAF89753 (Get FASTA)   NCBI Sequence Viewer  
  AAI17423 (Get FASTA)   NCBI Sequence Viewer  
  AAY82267 (Get FASTA)   NCBI Sequence Viewer  
  AAY82268 (Get FASTA)   NCBI Sequence Viewer  
  AAY82269 (Get FASTA)   NCBI Sequence Viewer  
  AAY82270 (Get FASTA)   NCBI Sequence Viewer  
  ABU41662 (Get FASTA)   NCBI Sequence Viewer  
  ABU41663 (Get FASTA)   NCBI Sequence Viewer  
  ABU41664 (Get FASTA)   NCBI Sequence Viewer  
  ACX46980 (Get FASTA)   NCBI Sequence Viewer  
  ACX46981 (Get FASTA)   NCBI Sequence Viewer  
  ACX46982 (Get FASTA)   NCBI Sequence Viewer  
  ACX46983 (Get FASTA)   NCBI Sequence Viewer  
  ACX46984 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69536 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69537 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69538 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69539 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69540 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69541 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69542 (Get FASTA)   NCBI Sequence Viewer  
  ACZ69543 (Get FASTA)   NCBI Sequence Viewer  
  AFX71929 (Get FASTA)   NCBI Sequence Viewer  
  AFX71930 (Get FASTA)   NCBI Sequence Viewer  
  AFX71931 (Get FASTA)   NCBI Sequence Viewer  
  AFX71932 (Get FASTA)   NCBI Sequence Viewer  
  AFX71933 (Get FASTA)   NCBI Sequence Viewer  
  AFX71934 (Get FASTA)   NCBI Sequence Viewer  
  AFX71935 (Get FASTA)   NCBI Sequence Viewer  
  AFX71936 (Get FASTA)   NCBI Sequence Viewer  
  AFX71937 (Get FASTA)   NCBI Sequence Viewer  
  AFX71938 (Get FASTA)   NCBI Sequence Viewer  
  AFX71939 (Get FASTA)   NCBI Sequence Viewer  
  AFX71940 (Get FASTA)   NCBI Sequence Viewer  
  AFX71941 (Get FASTA)   NCBI Sequence Viewer  
  AFX71942 (Get FASTA)   NCBI Sequence Viewer  
  AFX71943 (Get FASTA)   NCBI Sequence Viewer  
  AFX71944 (Get FASTA)   NCBI Sequence Viewer  
  AFX71945 (Get FASTA)   NCBI Sequence Viewer  
  AFX71946 (Get FASTA)   NCBI Sequence Viewer  
  AFX71947 (Get FASTA)   NCBI Sequence Viewer  
  AFX71948 (Get FASTA)   NCBI Sequence Viewer  
  AFX71949 (Get FASTA)   NCBI Sequence Viewer  
  AFX71950 (Get FASTA)   NCBI Sequence Viewer  
  AFX71951 (Get FASTA)   NCBI Sequence Viewer  
  AFX71952 (Get FASTA)   NCBI Sequence Viewer  
  AFX71953 (Get FASTA)   NCBI Sequence Viewer  
  AFX71954 (Get FASTA)   NCBI Sequence Viewer  
  AFX71955 (Get FASTA)   NCBI Sequence Viewer  
  AFX71956 (Get FASTA)   NCBI Sequence Viewer  
  AFX71957 (Get FASTA)   NCBI Sequence Viewer  
  AFX71958 (Get FASTA)   NCBI Sequence Viewer  
  AFX71959 (Get FASTA)   NCBI Sequence Viewer  
  AFX71960 (Get FASTA)   NCBI Sequence Viewer  
  AFX71961 (Get FASTA)   NCBI Sequence Viewer  
  AFX71962 (Get FASTA)   NCBI Sequence Viewer  
  AFX71963 (Get FASTA)   NCBI Sequence Viewer  
  AFX71964 (Get FASTA)   NCBI Sequence Viewer  
  AFX71965 (Get FASTA)   NCBI Sequence Viewer  
  AFX71966 (Get FASTA)   NCBI Sequence Viewer  
  AFX71967 (Get FASTA)   NCBI Sequence Viewer  
  AFX71968 (Get FASTA)   NCBI Sequence Viewer  
  AFX71969 (Get FASTA)   NCBI Sequence Viewer  
  AFX71970 (Get FASTA)   NCBI Sequence Viewer  
  AFX71971 (Get FASTA)   NCBI Sequence Viewer  
  AFX71972 (Get FASTA)   NCBI Sequence Viewer  
  AFX71973 (Get FASTA)   NCBI Sequence Viewer  
  AFX71974 (Get FASTA)   NCBI Sequence Viewer  
  AFX71975 (Get FASTA)   NCBI Sequence Viewer  
  AFX71976 (Get FASTA)   NCBI Sequence Viewer  
  AFX71977 (Get FASTA)   NCBI Sequence Viewer  
  AFX71978 (Get FASTA)   NCBI Sequence Viewer  
  AFX71979 (Get FASTA)   NCBI Sequence Viewer  
  AFX71980 (Get FASTA)   NCBI Sequence Viewer  
  AFX71981 (Get FASTA)   NCBI Sequence Viewer  
  AFX71982 (Get FASTA)   NCBI Sequence Viewer  
  AFX71983 (Get FASTA)   NCBI Sequence Viewer  
  AFX71984 (Get FASTA)   NCBI Sequence Viewer  
  AFX71985 (Get FASTA)   NCBI Sequence Viewer  
  AFX71986 (Get FASTA)   NCBI Sequence Viewer  
  AFX71987 (Get FASTA)   NCBI Sequence Viewer  
  AFX71988 (Get FASTA)   NCBI Sequence Viewer  
  AFX71989 (Get FASTA)   NCBI Sequence Viewer  
  AFX71990 (Get FASTA)   NCBI Sequence Viewer  
  AFX71991 (Get FASTA)   NCBI Sequence Viewer  
  AFX71992 (Get FASTA)   NCBI Sequence Viewer  
  AFX71993 (Get FASTA)   NCBI Sequence Viewer  
  AFX71994 (Get FASTA)   NCBI Sequence Viewer  
  AFX71995 (Get FASTA)   NCBI Sequence Viewer  
  AFX71996 (Get FASTA)   NCBI Sequence Viewer  
  AFX71997 (Get FASTA)   NCBI Sequence Viewer  
  AFX71998 (Get FASTA)   NCBI Sequence Viewer  
  AFX71999 (Get FASTA)   NCBI Sequence Viewer  
  AFX72000 (Get FASTA)   NCBI Sequence Viewer  
  AFX72001 (Get FASTA)   NCBI Sequence Viewer  
  AFX72002 (Get FASTA)   NCBI Sequence Viewer  
  AFX72003 (Get FASTA)   NCBI Sequence Viewer  
  AFX72004 (Get FASTA)   NCBI Sequence Viewer  
  AFX72005 (Get FASTA)   NCBI Sequence Viewer  
  AFX72006 (Get FASTA)   NCBI Sequence Viewer  
  AFX72007 (Get FASTA)   NCBI Sequence Viewer  
  AFX72008 (Get FASTA)   NCBI Sequence Viewer  
  AFX72009 (Get FASTA)   NCBI Sequence Viewer  
  AFX72010 (Get FASTA)   NCBI Sequence Viewer  
  AFX72011 (Get FASTA)   NCBI Sequence Viewer  
  AFX72012 (Get FASTA)   NCBI Sequence Viewer  
  AFX72013 (Get FASTA)   NCBI Sequence Viewer  
  AFX72014 (Get FASTA)   NCBI Sequence Viewer  
  AFX72015 (Get FASTA)   NCBI Sequence Viewer  
  AFX72016 (Get FASTA)   NCBI Sequence Viewer  
  AFX72017 (Get FASTA)   NCBI Sequence Viewer  
  AFX72018 (Get FASTA)   NCBI Sequence Viewer  
  AFX72019 (Get FASTA)   NCBI Sequence Viewer  
  AFX72020 (Get FASTA)   NCBI Sequence Viewer  
  AFX72021 (Get FASTA)   NCBI Sequence Viewer  
  AFX72022 (Get FASTA)   NCBI Sequence Viewer  
  AFX72023 (Get FASTA)   NCBI Sequence Viewer  
  AFX72024 (Get FASTA)   NCBI Sequence Viewer  
  AFX72025 (Get FASTA)   NCBI Sequence Viewer  
  AFX72026 (Get FASTA)   NCBI Sequence Viewer  
  AFX72027 (Get FASTA)   NCBI Sequence Viewer  
  AFX72028 (Get FASTA)   NCBI Sequence Viewer  
  AFX72029 (Get FASTA)   NCBI Sequence Viewer  
  AFX72030 (Get FASTA)   NCBI Sequence Viewer  
  AFX72031 (Get FASTA)   NCBI Sequence Viewer  
  AFX72032 (Get FASTA)   NCBI Sequence Viewer  
  AFX72033 (Get FASTA)   NCBI Sequence Viewer  
  AFX72034 (Get FASTA)   NCBI Sequence Viewer  
  AFX72035 (Get FASTA)   NCBI Sequence Viewer  
  AFX72036 (Get FASTA)   NCBI Sequence Viewer  
  AFX72037 (Get FASTA)   NCBI Sequence Viewer  
  AFX72038 (Get FASTA)   NCBI Sequence Viewer  
  AFX72039 (Get FASTA)   NCBI Sequence Viewer  
  AFX72040 (Get FASTA)   NCBI Sequence Viewer  
  AFX72041 (Get FASTA)   NCBI Sequence Viewer  
  AFX72042 (Get FASTA)   NCBI Sequence Viewer  
  AFX72043 (Get FASTA)   NCBI Sequence Viewer  
  AFX72044 (Get FASTA)   NCBI Sequence Viewer  
  AFX72045 (Get FASTA)   NCBI Sequence Viewer  
  AFX72046 (Get FASTA)   NCBI Sequence Viewer  
  AFX72047 (Get FASTA)   NCBI Sequence Viewer  
  AFX72048 (Get FASTA)   NCBI Sequence Viewer  
  AFX72049 (Get FASTA)   NCBI Sequence Viewer  
  AFX72050 (Get FASTA)   NCBI Sequence Viewer  
  AFX72051 (Get FASTA)   NCBI Sequence Viewer  
  AFX72052 (Get FASTA)   NCBI Sequence Viewer  
  AFX72053 (Get FASTA)   NCBI Sequence Viewer  
  AFX72054 (Get FASTA)   NCBI Sequence Viewer  
  AFX72055 (Get FASTA)   NCBI Sequence Viewer  
  AFX72056 (Get FASTA)   NCBI Sequence Viewer  
  AFX72057 (Get FASTA)   NCBI Sequence Viewer  
  AFX72058 (Get FASTA)   NCBI Sequence Viewer  
  AFX72059 (Get FASTA)   NCBI Sequence Viewer  
  AFX72060 (Get FASTA)   NCBI Sequence Viewer  
  AFX72061 (Get FASTA)   NCBI Sequence Viewer  
  AFX72062 (Get FASTA)   NCBI Sequence Viewer  
  AFX72063 (Get FASTA)   NCBI Sequence Viewer  
  AFX72064 (Get FASTA)   NCBI Sequence Viewer  
  AFX72065 (Get FASTA)   NCBI Sequence Viewer  
  AFX72066 (Get FASTA)   NCBI Sequence Viewer  
  AFX72067 (Get FASTA)   NCBI Sequence Viewer  
  AFX72068 (Get FASTA)   NCBI Sequence Viewer  
  AFX72069 (Get FASTA)   NCBI Sequence Viewer  
  AFX72070 (Get FASTA)   NCBI Sequence Viewer  
  AFX72071 (Get FASTA)   NCBI Sequence Viewer  
  AFX72072 (Get FASTA)   NCBI Sequence Viewer  
  AFX72073 (Get FASTA)   NCBI Sequence Viewer  
  AFX72074 (Get FASTA)   NCBI Sequence Viewer  
  AFX72075 (Get FASTA)   NCBI Sequence Viewer  
  AFX72076 (Get FASTA)   NCBI Sequence Viewer  
  AFX72077 (Get FASTA)   NCBI Sequence Viewer  
  AFX72078 (Get FASTA)   NCBI Sequence Viewer  
  AFX72079 (Get FASTA)   NCBI Sequence Viewer  
  AFX72080 (Get FASTA)   NCBI Sequence Viewer  
  AFX72081 (Get FASTA)   NCBI Sequence Viewer  
  AFX72082 (Get FASTA)   NCBI Sequence Viewer  
  AFX72083 (Get FASTA)   NCBI Sequence Viewer  
  AFX72084 (Get FASTA)   NCBI Sequence Viewer  
  AFX72085 (Get FASTA)   NCBI Sequence Viewer  
  AFX72086 (Get FASTA)   NCBI Sequence Viewer  
  AFX72087 (Get FASTA)   NCBI Sequence Viewer  
  AFX72088 (Get FASTA)   NCBI Sequence Viewer  
  AFX72089 (Get FASTA)   NCBI Sequence Viewer  
  AFX72090 (Get FASTA)   NCBI Sequence Viewer  
  AFX72091 (Get FASTA)   NCBI Sequence Viewer  
  AFX72092 (Get FASTA)   NCBI Sequence Viewer  
  AFX72093 (Get FASTA)   NCBI Sequence Viewer  
  AFX72094 (Get FASTA)   NCBI Sequence Viewer  
  AFX72095 (Get FASTA)   NCBI Sequence Viewer  
  AFX72096 (Get FASTA)   NCBI Sequence Viewer  
  AFX72097 (Get FASTA)   NCBI Sequence Viewer  
  AFX72098 (Get FASTA)   NCBI Sequence Viewer  
  AFX72099 (Get FASTA)   NCBI Sequence Viewer  
  AFX72100 (Get FASTA)   NCBI Sequence Viewer  
  AFX72101 (Get FASTA)   NCBI Sequence Viewer  
  AFX72102 (Get FASTA)   NCBI Sequence Viewer  
  AFX72103 (Get FASTA)   NCBI Sequence Viewer  
  AFX72104 (Get FASTA)   NCBI Sequence Viewer  
  AFX72105 (Get FASTA)   NCBI Sequence Viewer  
  AFX72106 (Get FASTA)   NCBI Sequence Viewer  
  AFX72107 (Get FASTA)   NCBI Sequence Viewer  
  AFX72108 (Get FASTA)   NCBI Sequence Viewer  
  AFX72109 (Get FASTA)   NCBI Sequence Viewer  
  AFX72110 (Get FASTA)   NCBI Sequence Viewer  
  AFX72111 (Get FASTA)   NCBI Sequence Viewer  
  AFX72112 (Get FASTA)   NCBI Sequence Viewer  
  AFX72113 (Get FASTA)   NCBI Sequence Viewer  
  AFX72114 (Get FASTA)   NCBI Sequence Viewer  
  AFX72115 (Get FASTA)   NCBI Sequence Viewer  
  AFX72116 (Get FASTA)   NCBI Sequence Viewer  
  AFX72117 (Get FASTA)   NCBI Sequence Viewer  
  AFX72118 (Get FASTA)   NCBI Sequence Viewer  
  AFX72119 (Get FASTA)   NCBI Sequence Viewer  
  AFX72120 (Get FASTA)   NCBI Sequence Viewer  
  AFX72121 (Get FASTA)   NCBI Sequence Viewer  
  AFX72122 (Get FASTA)   NCBI Sequence Viewer  
  AFX72123 (Get FASTA)   NCBI Sequence Viewer  
  AFX72124 (Get FASTA)   NCBI Sequence Viewer  
  AFX72125 (Get FASTA)   NCBI Sequence Viewer  
  AFX72126 (Get FASTA)   NCBI Sequence Viewer  
  AFX72127 (Get FASTA)   NCBI Sequence Viewer  
  AFX72128 (Get FASTA)   NCBI Sequence Viewer  
  AFX72129 (Get FASTA)   NCBI Sequence Viewer  
  AFX72130 (Get FASTA)   NCBI Sequence Viewer  
  AFX72131 (Get FASTA)   NCBI Sequence Viewer  
  AFX72132 (Get FASTA)   NCBI Sequence Viewer  
  AFX72133 (Get FASTA)   NCBI Sequence Viewer  
  AFX72134 (Get FASTA)   NCBI Sequence Viewer  
  AFX72135 (Get FASTA)   NCBI Sequence Viewer  
  AFX72136 (Get FASTA)   NCBI Sequence Viewer  
  AFX72137 (Get FASTA)   NCBI Sequence Viewer  
  AFX72138 (Get FASTA)   NCBI Sequence Viewer  
  AFX72139 (Get FASTA)   NCBI Sequence Viewer  
  AFX72140 (Get FASTA)   NCBI Sequence Viewer  
  AFX72141 (Get FASTA)   NCBI Sequence Viewer  
  AFX72142 (Get FASTA)   NCBI Sequence Viewer  
  AFX72143 (Get FASTA)   NCBI Sequence Viewer  
  AFX72144 (Get FASTA)   NCBI Sequence Viewer  
  AFX72145 (Get FASTA)   NCBI Sequence Viewer  
  AFX72146 (Get FASTA)   NCBI Sequence Viewer  
  AFX72147 (Get FASTA)   NCBI Sequence Viewer  
  AFX72148 (Get FASTA)   NCBI Sequence Viewer  
  AFX72149 (Get FASTA)   NCBI Sequence Viewer  
  AFX72150 (Get FASTA)   NCBI Sequence Viewer  
  AFX72151 (Get FASTA)   NCBI Sequence Viewer  
  AFX72152 (Get FASTA)   NCBI Sequence Viewer  
  AFX72153 (Get FASTA)   NCBI Sequence Viewer  
  AFX72154 (Get FASTA)   NCBI Sequence Viewer  
  AFX72155 (Get FASTA)   NCBI Sequence Viewer  
  AFX72156 (Get FASTA)   NCBI Sequence Viewer  
  AFX72157 (Get FASTA)   NCBI Sequence Viewer  
  AFX72158 (Get FASTA)   NCBI Sequence Viewer  
  AFX72159 (Get FASTA)   NCBI Sequence Viewer  
  AFX72160 (Get FASTA)   NCBI Sequence Viewer  
  AFX72161 (Get FASTA)   NCBI Sequence Viewer  
  AFX72162 (Get FASTA)   NCBI Sequence Viewer  
  AFX72163 (Get FASTA)   NCBI Sequence Viewer  
  AFX72164 (Get FASTA)   NCBI Sequence Viewer  
  AFX72165 (Get FASTA)   NCBI Sequence Viewer  
  AFX72166 (Get FASTA)   NCBI Sequence Viewer  
  AFX72167 (Get FASTA)   NCBI Sequence Viewer  
  AFX72168 (Get FASTA)   NCBI Sequence Viewer  
  AFX72169 (Get FASTA)   NCBI Sequence Viewer  
  AFX72170 (Get FASTA)   NCBI Sequence Viewer  
  AFX72171 (Get FASTA)   NCBI Sequence Viewer  
  AFX72172 (Get FASTA)   NCBI Sequence Viewer  
  AFX72173 (Get FASTA)   NCBI Sequence Viewer  
  AFX72174 (Get FASTA)   NCBI Sequence Viewer  
  AFX72175 (Get FASTA)   NCBI Sequence Viewer  
  AFX72176 (Get FASTA)   NCBI Sequence Viewer  
  AFX72177 (Get FASTA)   NCBI Sequence Viewer  
  AFX72178 (Get FASTA)   NCBI Sequence Viewer  
  AFX72179 (Get FASTA)   NCBI Sequence Viewer  
  AFX72180 (Get FASTA)   NCBI Sequence Viewer  
  AFX72181 (Get FASTA)   NCBI Sequence Viewer  
  AFX72182 (Get FASTA)   NCBI Sequence Viewer  
  AFX72183 (Get FASTA)   NCBI Sequence Viewer  
  AFX72184 (Get FASTA)   NCBI Sequence Viewer  
  AFX72185 (Get FASTA)   NCBI Sequence Viewer  
  AFX72186 (Get FASTA)   NCBI Sequence Viewer  
  AFX72187 (Get FASTA)   NCBI Sequence Viewer  
  AFX72188 (Get FASTA)   NCBI Sequence Viewer  
  AFX72189 (Get FASTA)   NCBI Sequence Viewer  
  AFX72190 (Get FASTA)   NCBI Sequence Viewer  
  AFX72191 (Get FASTA)   NCBI Sequence Viewer  
  AFX72192 (Get FASTA)   NCBI Sequence Viewer  
  AFX72193 (Get FASTA)   NCBI Sequence Viewer  
  AFX72194 (Get FASTA)   NCBI Sequence Viewer  
  AFX72195 (Get FASTA)   NCBI Sequence Viewer  
  AFX72196 (Get FASTA)   NCBI Sequence Viewer  
  AFX72197 (Get FASTA)   NCBI Sequence Viewer  
  AFX72198 (Get FASTA)   NCBI Sequence Viewer  
  AFX72199 (Get FASTA)   NCBI Sequence Viewer  
  AFX72200 (Get FASTA)   NCBI Sequence Viewer  
  AFX72201 (Get FASTA)   NCBI Sequence Viewer  
  AFX72202 (Get FASTA)   NCBI Sequence Viewer  
  AFX72203 (Get FASTA)   NCBI Sequence Viewer  
  AFX72204 (Get FASTA)   NCBI Sequence Viewer  
  AFX72205 (Get FASTA)   NCBI Sequence Viewer  
  AFX72206 (Get FASTA)   NCBI Sequence Viewer  
  AFX72207 (Get FASTA)   NCBI Sequence Viewer  
  AFX72208 (Get FASTA)   NCBI Sequence Viewer  
  AFX72209 (Get FASTA)   NCBI Sequence Viewer  
  AFX72210 (Get FASTA)   NCBI Sequence Viewer  
  AFX72211 (Get FASTA)   NCBI Sequence Viewer  
  AFX72212 (Get FASTA)   NCBI Sequence Viewer  
  AFX72213 (Get FASTA)   NCBI Sequence Viewer  
  AFX72214 (Get FASTA)   NCBI Sequence Viewer  
  AFX72215 (Get FASTA)   NCBI Sequence Viewer  
  AFX72216 (Get FASTA)   NCBI Sequence Viewer  
  AFX72217 (Get FASTA)   NCBI Sequence Viewer  
  AFX72218 (Get FASTA)   NCBI Sequence Viewer  
  AFX72219 (Get FASTA)   NCBI Sequence Viewer  
  AFX72220 (Get FASTA)   NCBI Sequence Viewer  
  AFX72221 (Get FASTA)   NCBI Sequence Viewer  
  AFX72222 (Get FASTA)   NCBI Sequence Viewer  
  AFX72223 (Get FASTA)   NCBI Sequence Viewer  
  AFX72224 (Get FASTA)   NCBI Sequence Viewer  
  AFX72225 (Get FASTA)   NCBI Sequence Viewer  
  AFX72226 (Get FASTA)   NCBI Sequence Viewer  
  AFX72227 (Get FASTA)   NCBI Sequence Viewer  
  AFX72228 (Get FASTA)   NCBI Sequence Viewer  
  AFX72229 (Get FASTA)   NCBI Sequence Viewer  
  AFX72230 (Get FASTA)   NCBI Sequence Viewer  
  AFX72231 (Get FASTA)   NCBI Sequence Viewer  
  AFX72232 (Get FASTA)   NCBI Sequence Viewer  
  AFX72233 (Get FASTA)   NCBI Sequence Viewer  
  AFX72234 (Get FASTA)   NCBI Sequence Viewer  
  AFX72235 (Get FASTA)   NCBI Sequence Viewer  
  AFX72236 (Get FASTA)   NCBI Sequence Viewer  
  AFX72237 (Get FASTA)   NCBI Sequence Viewer  
  AFX72238 (Get FASTA)   NCBI Sequence Viewer  
  AFX72239 (Get FASTA)   NCBI Sequence Viewer  
  AFX72240 (Get FASTA)   NCBI Sequence Viewer  
  AFX72241 (Get FASTA)   NCBI Sequence Viewer  
  AFX72242 (Get FASTA)   NCBI Sequence Viewer  
  AFX72243 (Get FASTA)   NCBI Sequence Viewer  
  AFX72244 (Get FASTA)   NCBI Sequence Viewer  
  AFX72245 (Get FASTA)   NCBI Sequence Viewer  
  AFX72246 (Get FASTA)   NCBI Sequence Viewer  
  AFX72247 (Get FASTA)   NCBI Sequence Viewer  
  AFX72248 (Get FASTA)   NCBI Sequence Viewer  
  AFX72249 (Get FASTA)   NCBI Sequence Viewer  
  AFX72250 (Get FASTA)   NCBI Sequence Viewer  
  AFX72251 (Get FASTA)   NCBI Sequence Viewer  
  AFX72252 (Get FASTA)   NCBI Sequence Viewer  
  AFX72253 (Get FASTA)   NCBI Sequence Viewer  
  AFX72254 (Get FASTA)   NCBI Sequence Viewer  
  AFX72255 (Get FASTA)   NCBI Sequence Viewer  
  AFX72256 (Get FASTA)   NCBI Sequence Viewer  
  AFX72257 (Get FASTA)   NCBI Sequence Viewer  
  AFX72258 (Get FASTA)   NCBI Sequence Viewer  
  AFX72259 (Get FASTA)   NCBI Sequence Viewer  
  AFX72260 (Get FASTA)   NCBI Sequence Viewer  
  AFX72261 (Get FASTA)   NCBI Sequence Viewer  
  AFX72262 (Get FASTA)   NCBI Sequence Viewer  
  AFX72263 (Get FASTA)   NCBI Sequence Viewer  
  AFX72264 (Get FASTA)   NCBI Sequence Viewer  
  AFX72265 (Get FASTA)   NCBI Sequence Viewer  
  AFX72266 (Get FASTA)   NCBI Sequence Viewer  
  AFX72267 (Get FASTA)   NCBI Sequence Viewer  
  AFX72268 (Get FASTA)   NCBI Sequence Viewer  
  AFX72269 (Get FASTA)   NCBI Sequence Viewer  
  AFX72270 (Get FASTA)   NCBI Sequence Viewer  
  AFX72271 (Get FASTA)   NCBI Sequence Viewer  
  AFX72272 (Get FASTA)   NCBI Sequence Viewer  
  AFX72273 (Get FASTA)   NCBI Sequence Viewer  
  AFX72274 (Get FASTA)   NCBI Sequence Viewer  
  AFX72275 (Get FASTA)   NCBI Sequence Viewer  
  AFX72276 (Get FASTA)   NCBI Sequence Viewer  
  AFX72277 (Get FASTA)   NCBI Sequence Viewer  
  AFX72278 (Get FASTA)   NCBI Sequence Viewer  
  AFX72279 (Get FASTA)   NCBI Sequence Viewer  
  AFX72280 (Get FASTA)   NCBI Sequence Viewer  
  AFX72281 (Get FASTA)   NCBI Sequence Viewer  
  AFX72282 (Get FASTA)   NCBI Sequence Viewer  
  AFX72283 (Get FASTA)   NCBI Sequence Viewer  
  AFX72284 (Get FASTA)   NCBI Sequence Viewer  
  AFX72285 (Get FASTA)   NCBI Sequence Viewer  
  AFX72286 (Get FASTA)   NCBI Sequence Viewer  
  AFX72287 (Get FASTA)   NCBI Sequence Viewer  
  AFX72288 (Get FASTA)   NCBI Sequence Viewer  
  AFX72289 (Get FASTA)   NCBI Sequence Viewer  
  AFX72290 (Get FASTA)   NCBI Sequence Viewer  
  AFX72291 (Get FASTA)   NCBI Sequence Viewer  
  AFX72292 (Get FASTA)   NCBI Sequence Viewer  
  AFX72293 (Get FASTA)   NCBI Sequence Viewer  
  AFX72294 (Get FASTA)   NCBI Sequence Viewer  
  AFX72295 (Get FASTA)   NCBI Sequence Viewer  
  AFX72296 (Get FASTA)   NCBI Sequence Viewer  
  AFX72297 (Get FASTA)   NCBI Sequence Viewer  
  AFX72298 (Get FASTA)   NCBI Sequence Viewer  
  AFX72299 (Get FASTA)   NCBI Sequence Viewer  
  AFX72300 (Get FASTA)   NCBI Sequence Viewer  
  AFX72301 (Get FASTA)   NCBI Sequence Viewer  
  AFX72302 (Get FASTA)   NCBI Sequence Viewer  
  AFX72303 (Get FASTA)   NCBI Sequence Viewer  
  AFX72304 (Get FASTA)   NCBI Sequence Viewer  
  AFX72305 (Get FASTA)   NCBI Sequence Viewer  
  AFX72306 (Get FASTA)   NCBI Sequence Viewer  
  AFX72307 (Get FASTA)   NCBI Sequence Viewer  
  AFX72308 (Get FASTA)   NCBI Sequence Viewer  
  AFX72309 (Get FASTA)   NCBI Sequence Viewer  
  AFX72310 (Get FASTA)   NCBI Sequence Viewer  
  AFX72311 (Get FASTA)   NCBI Sequence Viewer  
  AFX72312 (Get FASTA)   NCBI Sequence Viewer  
  AFX72313 (Get FASTA)   NCBI Sequence Viewer  
  AFX72314 (Get FASTA)   NCBI Sequence Viewer  
  AFX72315 (Get FASTA)   NCBI Sequence Viewer  
  AFX72316 (Get FASTA)   NCBI Sequence Viewer  
  AFX72317 (Get FASTA)   NCBI Sequence Viewer  
  AZI70866 (Get FASTA)   NCBI Sequence Viewer  
  BAF82742 (Get FASTA)   NCBI Sequence Viewer  
  BAF85757 (Get FASTA)   NCBI Sequence Viewer  
  BAG55035 (Get FASTA)   NCBI Sequence Viewer  
  BAG64706 (Get FASTA)   NCBI Sequence Viewer  
  CAS02255 (Get FASTA)   NCBI Sequence Viewer  
  CAT16978 (Get FASTA)   NCBI Sequence Viewer  
  EAW87448 (Get FASTA)   NCBI Sequence Viewer  
  EAW87449 (Get FASTA)   NCBI Sequence Viewer  
  EAW87451 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000363089
  ENSP00000363089.5
  ENSP00000377997
  ENSP00000377997.4
  ENSP00000496429.1
GenBank Protein O00206 (Get FASTA)   NCBI Sequence Viewer  
  QLJ58258 (Get FASTA)   NCBI Sequence Viewer  
  UZF98900 (Get FASTA)   NCBI Sequence Viewer  
  UZF98901 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_612564   ⟸   NM_138554
- Peptide Label: isoform A precursor
- UniProtKB: Q9UK78 (UniProtKB/Swiss-Prot),   Q5VZI9 (UniProtKB/Swiss-Prot),   Q5VZI8 (UniProtKB/Swiss-Prot),   D1CS53 (UniProtKB/Swiss-Prot),   D1CS52 (UniProtKB/Swiss-Prot),   B4E194 (UniProtKB/Swiss-Prot),   A9XLQ1 (UniProtKB/Swiss-Prot),   A9XLQ0 (UniProtKB/Swiss-Prot),   A9XLP9 (UniProtKB/Swiss-Prot),   A8K1Y8 (UniProtKB/Swiss-Prot),   Q9UM57 (UniProtKB/Swiss-Prot),   O00206 (UniProtKB/Swiss-Prot),   D1CS55 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_003257   ⟸   NM_003266
- Peptide Label: isoform C
- UniProtKB: D1CS55 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_612567   ⟸   NM_138557
- Peptide Label: isoform D
- UniProtKB: O00206 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000496429   ⟸   ENST00000472304
RefSeq Acc Id: ENSP00000363089   ⟸   ENST00000355622
RefSeq Acc Id: ENSP00000377997   ⟸   ENST00000394487
Protein Domains
LRRCT   TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O00206-F1-model_v2 AlphaFold O00206 1-839 view protein structure

Promoters
RGD ID:7216009
Promoter ID:EPDNEW_H13750
Type:initiation region
Name:TLR4_2
Description:toll like receptor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H13752  EPDNEW_H13751  EPDNEW_H13753  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh389117,704,182 - 117,704,242EPDNEW
RGD ID:7216013
Promoter ID:EPDNEW_H13751
Type:initiation region
Name:TLR4_1
Description:toll like receptor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H13750  EPDNEW_H13752  EPDNEW_H13753  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh389117,704,403 - 117,704,463EPDNEW
RGD ID:7216011
Promoter ID:EPDNEW_H13752
Type:initiation region
Name:TLR4_3
Description:toll like receptor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H13750  EPDNEW_H13751  EPDNEW_H13753  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh389117,714,505 - 117,714,565EPDNEW
RGD ID:7216015
Promoter ID:EPDNEW_H13753
Type:initiation region
Name:TLR4_4
Description:toll like receptor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H13750  EPDNEW_H13752  EPDNEW_H13751  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh389117,715,992 - 117,716,052EPDNEW
RGD ID:6808302
Promoter ID:HG_KWN:64705
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   Lymphoblastoid,   NB4
Transcripts:ENST00000355622,   UC004BKA.1,   UC004BKB.1
Position:
Human AssemblyChrPosition (strand)Source
Build 369119,506,264 - 119,506,764 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11850 AgrOrtholog
COSMIC TLR4 COSMIC
Ensembl Genes ENSG00000136869 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000355622 ENTREZGENE
  ENST00000355622.8 UniProtKB/Swiss-Prot
  ENST00000394487 ENTREZGENE
  ENST00000394487.5 UniProtKB/Swiss-Prot
  ENST00000472304.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000136869 GTEx
HGNC ID HGNC:11850 ENTREZGENE
Human Proteome Map TLR4 Human Proteome Map
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toll-like_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7099 UniProtKB/Swiss-Prot
NCBI Gene 7099 ENTREZGENE
OMIM 603030 OMIM
PANTHER FI03225P UniProtKB/TrEMBL
  FISH-LIPS, ISOFORM E UniProtKB/TrEMBL
  PTHR24365 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN UniProtKB/TrEMBL
  TOLL-LIKE RECEPTOR 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36552 PharmGKB, RGD
PIRSF Toll-like_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  Outer arm dynein light chain 1 UniProtKB/Swiss-Prot
  RNI-like UniProtKB/Swiss-Prot
  SSF52200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8Y7P4_HUMAN UniProtKB/TrEMBL
  A0A3Q8PZA0_HUMAN UniProtKB/TrEMBL
  A0A7D5XLN4_HUMAN UniProtKB/TrEMBL
  A8K1Y8 ENTREZGENE
  A9XLP9 ENTREZGENE
  A9XLQ0 ENTREZGENE
  A9XLQ1 ENTREZGENE
  B4E194 ENTREZGENE
  D1CS52 ENTREZGENE
  D1CS53 ENTREZGENE
  D1CS55 ENTREZGENE, UniProtKB/TrEMBL
  D2JYI2_HUMAN UniProtKB/TrEMBL
  D2JYI3_HUMAN UniProtKB/TrEMBL
  D2JYI4_HUMAN UniProtKB/TrEMBL
  D2JYI5_HUMAN UniProtKB/TrEMBL
  D2JYI6_HUMAN UniProtKB/TrEMBL
  D2JYI7_HUMAN UniProtKB/TrEMBL
  D2JYI8_HUMAN UniProtKB/TrEMBL
  D2JYI9_HUMAN UniProtKB/TrEMBL
  O00206 ENTREZGENE
  Q5VZI8 ENTREZGENE
  Q5VZI9 ENTREZGENE
  Q9UK78 ENTREZGENE
  Q9UM57 ENTREZGENE
  TLR4_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A8K1Y8 UniProtKB/Swiss-Prot
  A9XLP9 UniProtKB/Swiss-Prot
  A9XLQ0 UniProtKB/Swiss-Prot
  A9XLQ1 UniProtKB/Swiss-Prot
  B4E194 UniProtKB/Swiss-Prot
  D1CS52 UniProtKB/Swiss-Prot
  D1CS53 UniProtKB/Swiss-Prot
  Q5VZI8 UniProtKB/Swiss-Prot
  Q5VZI9 UniProtKB/Swiss-Prot
  Q9UK78 UniProtKB/Swiss-Prot
  Q9UM57 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-26 TLR4  toll like receptor 4    toll-like receptor 4  Symbol and/or name change 5135510 APPROVED