BAD (BCL2-associated agonist of cell death)

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Keyword

Gene: BAD (BCL2-associated agonist of cell death) Homo sapiens

Symbol:

BAD

Name:

BCL2-associated agonist of cell death

Description:

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

BBC2; bcl-2 associated death agonist; bcl-2-binding component 6; bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; bcl2 antagonist of cell death; BCL2-antagonist of cell death; BCL2-antagonist of cell death protein; BCL2-binding component 6; BCL2-binding protein; bcl2-L-8; BCL2L8; OTTHUMP00000165928; OTTHUMP00000165929

Orthologs:

Mus musculus : Bad (BCL2-associated agonist of cell death) MGI
Rattus norvegicus : Bad (BCL2-associated agonist of cell death)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	11	63,956,625 - 63,971,484	-	NCBI
Human Genome Assembly HuRef	11	60,365,093 - 60,379,900	-	NCBI
Human Genome Assembly GRCh37	11	64,037,300 - 64,052,176	-	NCBI
Human Genome Assembly Build 36	11	63,793,878 - 63,808,740	-	NCBI
Human Cytogenetic Map	11	q13.1		NCBI
Human Genome Assembly	11	63,793,877 - 63,808,740		NCBI