Gene: VEGFA (vascular endothelial growth factor A)  Homo sapiens
Symbol: VEGFA
Name: vascular endothelial growth factor A
Description: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC70609; MVCD1; OTTHUMP00000016487; OTTHUMP00000016488; OTTHUMP00000165985; OTTHUMP00000165986; OTTHUMP00000165987; OTTHUMP00000224107; OTTHUMP00000224108; OTTHUMP00000224109; OTTHUMP00000224153; OTTHUMP00000224154; OTTHUMP00000224423; OTTHUMP00000224424; OTTHUMP00000224425; OTTHUMP00000224426; OTTHUMP00000224427; OTTHUMP00000224428; OTTHUMP00000224429; OTTHUMP00000224430; vascular endothelial growth factor; vascular endothelial growth factor A; vascular permeability factor; VEGF; VEGF-A; VPF
Orthologs: Mus musculus : Vegfa (vascular endothelial growth factor A)  MGI
Rattus norvegicus : Vegfa (vascular endothelial growth factor A)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1643,648,511 - 43,664,790+NCBI
Human Genome Assembly HuRef643,458,106 - 43,474,385+NCBI
Human Genome Assembly GRCh37643,737,946 - 43,754,224+NCBI
Human Genome Assembly Build 36643,845,931 - 43,862,202+NCBI
Human Cytogenetic Map6p12 NCBI
Human Genome Assembly643,845,923 - 43,860,314 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

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References - curated
References - uncurated