Gene: COX6A2 (cytochrome c oxidase subunit VIa polypeptide 2)  Homo sapiens

Symbol: COX6A2
Name: cytochrome c oxidase subunit VIa polypeptide 2
Description: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: COX VIa-M; COX6AH; COXVIAH; cytochrome c oxidase polypeptide VIa-heart; cytochrome c oxidase subunit 6A2, mitochondrial; cytochrome c oxidase subunit VIA-muscle; OTTHUMP00000163297
Orthologs: Mus musculus : Cox6a2 (cytochrome c oxidase subunit VIa polypeptide 2)  MGI
Rattus norvegicus : Cox6a2 (cytochrome c oxidase subunit VIa polypeptide 2)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11632,440,117 - 32,440,814-NCBI
Human Genome Assembly HuRef1628,999,436 - 29,000,138-NCBI
Human Genome Assembly GRCh371631,439,052 - 31,439,749-NCBI
Human Celera Assembly1628,868,661 - 28,869,331+NCBI
Human Genome Assembly Build 361631,346,556 - 31,347,222-NCBI
Human Cytogenetic Map16p11.12 NCBI
Human Genome Assembly1631,346,555 - 31,347,222 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on COX6A2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736247
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE