BAK1 (BCL2-antagonist/killer 1) - Rat Genome Database

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Keyword

Gene: BAK1 (BCL2-antagonist/killer 1) Homo sapiens

Symbol:

BAK1

Name:

BCL2-antagonist/killer 1

Description:

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

apoptosis regulator BAK; BAK; BAK-LIKE; bcl-2 homologous antagonist/killer; bcl-2-like protein 7; bcl2-L-7; BCL2-like 7 protein; BCL2L7; CDN1; MGC117255; MGC3887; OTTHUMP00000016211; pro-apoptotic protein BAK

Orthologs:

Mus musculus : Bak1 (BCL2-antagonist/killer 1) MGI
Rattus norvegicus : Bak1 (BCL2-antagonist/killer 1)

Related Pseudogenes:

BAK1P1 BAK1P2

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	6	33,455,848 - 33,463,595	-	NCBI
Human Genome Assembly HuRef	6	33,281,784 - 33,289,531	-	NCBI
Human Genome Assembly GRCh37	6	33,540,323 - 33,548,070	-	NCBI
Human Genome Assembly Build 36	6	33,648,301 - 33,656,048	-	NCBI
Human Cytogenetic Map	6	p21.3		NCBI
Human Genome Assembly	6	33,648,306 - 33,655,959		NCBI