ID2 (inhibitor of DNA binding 2, dominant negative helix-loop-helix protein)

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Keyword

Gene: ID2 (inhibitor of DNA binding 2, dominant negative helix-loop-helix protein) Homo sapiens

Symbol:

ID2

Name:

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

Description:

The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

bHLHb26; cell growth-inhibiting gene 8; class B basic helix-loop-helix protein 26; DNA-binding protein inhibitor ID-2; DNA-binding protein inhibitor ID2; GIG8; helix-loop-helix protein ID2; ID2A; ID2H; inhibitor of differentiation 2; MGC26389; OTTHUMP00000140258; OTTHUMP00000200297

Orthologs:

Mus musculus : Id2 (inhibitor of DNA binding 2) MGI
Rattus norvegicus : Id2 (inhibitor of DNA binding 2)

Related Pseudogenes:

ID2B

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	8,794,575 - 8,797,045	+	NCBI
Human Genome Assembly HuRef	2	8,668,297 - 8,670,767	+	NCBI
Human Genome Assembly GRCh37	2	8,822,113 - 8,824,583	+	NCBI
Human Genome Assembly Build 36	2	8,739,564 - 8,742,034	+	NCBI
Human Cytogenetic Map	2	p25		NCBI
Human Genome Assembly	2	8,772,710 - 8,775,179		NCBI