(+)-alpha-viniferin increases activity EXP 6480464 alpha-viniferin analog results in increased activity of CASP8 protein and alpha-viniferin results in increased activity of CASP8 protein CTD PMID:16158945 (+)-catechin increases activity EXP 6480464 Catechin results in increased activity of CASP8 protein CTD PMID:20206613 (+)-dexrazoxane increases expression ISO Casp8 (Mus musculus) 6480464 Dexrazoxane results in increased expression of CASP8 mRNA CTD PMID:26873546 (+)-Tetrandrine multiple interactions EXP 6480464 tetrandrine results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:26822499 (+)-Tetrandrine increases cleavage EXP 6480464 tetrandrine results in increased cleavage of CASP8 protein CTD PMID:25266202 (+)-Tetrandrine increases expression EXP 6480464 tetrandrine results in increased expression of CASP8 protein CTD PMID:31255635 (-)-anisomycin increases activity EXP 6480464 Anisomycin results in increased activity of CASP8 protein CTD PMID:18241849 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CASP8 mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate multiple interactions ISO Casp8 (Mus musculus) 6480464 epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP8 protein] CTD PMID:37286014 (-)-gambogic acid multiple interactions EXP 6480464 [gambogic acid co-treated with Bortezomib] results in increased activity of CASP8 protein and [Verapamil co-treated with gambogic acid] results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:24291039 and PMID:24373880 (1->4)-beta-D-glucan multiple interactions ISO Casp8 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CASP8 mRNA CTD PMID:36331819 (20S)-ginsenoside Rg3 multiple interactions EXP 6480464 ginsenoside Rg3 inhibits the reaction [cagA protein and Helicobacter pylori results in decreased cleavage of CASP8 protein] CTD PMID:26427350 (R)-carnitine multiple interactions EXP 6480464 Carnitine inhibits the reaction [quinone results in increased activity of CASP8 protein] CTD PMID:32478940 (R)-lipoic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in decreased expression of CASP8 mRNA CTD PMID:23830814 (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Zinc Oxide analog results in increased activity of CASP8 protein] CTD PMID:27544635 (R)-noradrenaline affects activity ISO Casp8 (Rattus norvegicus) 6480464 Norepinephrine affects the activity of CASP8 protein CTD PMID:25437044 (R,R,R)-alpha-tocopherol increases cleavage EXP 6480464 alpha-Tocopherol analog results in increased cleavage of CASP8 protein CTD PMID:20686688 (S)-colchicine increases expression ISO Casp8 (Rattus norvegicus) 6480464 Colchicine results in increased expression of CASP8 mRNA CTD PMID:18255150 (S)-nicotine affects expression ISO Casp8 (Rattus norvegicus) 6480464 Nicotine affects the expression of CASP8 mRNA CTD PMID:20426880 (Z)-3-butylidenephthalide increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 butylidenephthalide results in increased cleavage of CASP8 protein CTD PMID:16987298 (Z)-3-butylidenephthalide increases cleavage EXP 6480464 butylidenephthalide results in increased cleavage of CASP8 protein CTD PMID:16987298 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression ISO Casp8 (Rattus norvegicus) 6480464 o and p'-DDT analog results in decreased expression of CASP8 mRNA CTD PMID:22937105 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO Casp8 (Rattus norvegicus) 6480464 o and p'-DDT results in increased expression of CASP8 mRNA CTD PMID:22937105 1,2-dichloroethane increases cleavage ISO Casp8 (Mus musculus) 6480464 ethylene dichloride results in increased cleavage of CASP8 protein CTD PMID:31520740 1,2-dimethylhydrazine multiple interactions ISO Casp8 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CASP8 mRNA CTD PMID:22206623 1,3-Dinitropyrene multiple interactions ISO Casp8 (Mus musculus) 6480464 1 and 3-dinitropyrene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:17240030 1,4-benzoquinone multiple interactions EXP 6480464 Carnitine inhibits the reaction [quinone results in increased activity of CASP8 protein] CTD PMID:32478940 1,4-benzoquinone increases activity EXP 6480464 quinone results in increased activity of CASP8 protein CTD PMID:32478940 1,4-dithiothreitol multiple interactions ISO Casp8 (Mus musculus) 6480464 Dithiothreitol inhibits the reaction [2-methyl-3-(2-((4-nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester results in decreased activity of CASP8 protein] CTD PMID:11226294 1,4-naphthoquinone increases activity EXP 6480464 1 and 4-naphthoquinone results in increased activity of CASP8 protein CTD PMID:20138029 1-nitropyrene multiple interactions ISO Casp8 (Mus musculus) 6480464 1-nitropyrene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:17240030 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15498850 17beta-estradiol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Caspase Inhibitors results in decreased activity of CASP8 protein] inhibits the reaction [Estradiol results in increased activity of CASP3 protein] more ... CTD PMID:15545282 more ... 17beta-estradiol increases expression EXP 6480464 Estradiol analog results in increased expression of CASP8 mRNA and Estradiol analog results in increased expression of CASP8 protein CTD PMID:36460128 17beta-estradiol decreases activity EXP 6480464 Estradiol results in decreased activity of CASP8 protein CTD PMID:31278978 17beta-estradiol increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Estradiol results in increased cleavage of CASP8 protein CTD PMID:15545282 17beta-estradiol increases activity EXP 6480464 Estradiol results in increased activity of CASP8 protein CTD PMID:19095654 17beta-estradiol 3-benzoate increases expression ISO Casp8 (Rattus norvegicus) 6480464 estradiol 3-benzoate results in increased expression of CASP8 mRNA CTD PMID:24316378 17beta-estradiol 3-benzoate multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 estradiol 3-benzoate results in increased expression of and results in increased activity of CASP8 protein more ... CTD PMID:24316378 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:20638727 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 wortmannin inhibits the reaction [2 more ... CTD PMID:24726520 2,2',4,4',5,5'-hexachlorobiphenyl affects expression EXP 6480464 2 more ... CTD PMID:20638727 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:26808241 2,2',4,4'-Tetrabromodiphenyl ether affects expression EXP 6480464 2 more ... CTD PMID:27589474 2,2',4,4'-Tetrabromodiphenyl ether affects activity EXP 6480464 2 more ... CTD PMID:27589474 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO Casp8 (Mus musculus) 6480464 2 more ... CTD PMID:25462306 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CASP8 mRNA CTD PMID:16039398 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Casp8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CASP8 mRNA CTD PMID:22666406 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Casp8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CASP8 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO Casp8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased activity of CASP8 protein CTD PMID:21846477 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Casp8 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CASP8 mRNA CTD PMID:19520675 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Casp8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CASP8 mRNA and Tetrachlorodibenzodioxin results in increased expression of CASP8 protein CTD PMID:12167310 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Casp8 (Mus musculus) 6480464 NFE2L2 gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CASP8 protein] and Tetrachlorodibenzodioxin results in increased cleavage of and affects the activity of CASP8 protein CTD PMID:15664267 and PMID:21846477 2,4,6-trinitrobenzenesulfonic acid decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form CTD PMID:30503585 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form] CTD PMID:30503585 2,4-D multiple interactions ISO Casp8 (Mus musculus) 6480464 FAS protein promotes the reaction [2 more ... CTD PMID:36214342 2,4-D increases expression ISO Casp8 (Rattus norvegicus) 6480464 2 more ... CTD PMID:36214342 2,4-D increases expression ISO Casp8 (Mus musculus) 6480464 2 more ... CTD PMID:36214342 2,4-D multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [2 more ... CTD PMID:36085217 and PMID:36214342 2,4-dinitrotoluene affects expression ISO Casp8 (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of CASP8 mRNA CTD PMID:21346803 2,5-hexanedione decreases expression ISO Casp8 (Mus musculus) 6480464 2 and 5-hexanedione results in decreased expression of CASP8 protein CTD PMID:33197454 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 [Verapamil co-treated with gambogic acid] results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:24373880 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases activity ISO Casp8 (Rattus norvegicus) 6480464 4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased activity of CASP8 protein CTD PMID:22983118 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Casp8 (Mus musculus) 6480464 3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide more ... CTD PMID:20558151 more ... 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid multiple interactions EXP 6480464 [anacardic acid co-treated with TNF protein] results in increased cleavage of CASP8 protein CTD PMID:18349320 2-methoxy-17beta-estradiol increases expression EXP 6480464 2-Methoxyestradiol results in increased expression of CASP8 protein modified form CTD PMID:23967052 25-hydroxycholesterol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 6-hydroxy-2 more ... CTD PMID:25845326 25-hydroxycholesterol increases activity ISO Casp8 (Rattus norvegicus) 6480464 25-hydroxycholesterol results in increased activity of CASP8 protein CTD PMID:25845326 28-deoxonimbolide increases activity EXP 6480464 28-deoxonimbolide results in increased activity of CASP8 protein CTD PMID:21381696 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Casp8 (Mus musculus) 6480464 3 more ... CTD PMID:31563530 3,3',5,5'-tetraiodothyroacetic acid increases expression EXP 6480464 tetraiodothyroacetic acid results in increased expression of CASP8 protein and tetraiodothyroacetic acid results in increased expression of CASP8 protein modified form CTD PMID:35151786 3,3',5,5'-tetraiodothyroacetic acid multiple interactions EXP 6480464 [tetraiodothyroacetic acid affects the susceptibility to heteronemin] which results in increased expression of CASP8 protein modified form and heteronemin promotes the reaction [tetraiodothyroacetic acid results in increased expression of CASP8 protein modified form] CTD PMID:35151786 3,4-methylenedioxymethamphetamine increases activity ISO Casp8 (Rattus norvegicus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased activity of CASP8 protein CTD PMID:22983118 and PMID:27255387 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide increases activity EXP 6480464 thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 3-chloropropane-1,2-diol increases activity EXP 6480464 alpha-Chlorohydrin results in increased activity of CASP8 protein CTD PMID:28070108 3-chloropropane-1,2-diol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:34915118 3-chloropropane-1,2-diol multiple interactions EXP 6480464 alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP8 protein and quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP8 protein] CTD PMID:27732882 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of CASP8 mRNA CTD PMID:27732882 3-hydroxybutyric acid multiple interactions ISO Casp8 (Mus musculus) 6480464 3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide and E coli O55-B5 co-treated with Galactosamine] results in increased expression of CASP8 protein] CTD PMID:31332890 3-methyladenine multiple interactions EXP 6480464 3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]] more ... CTD PMID:20104024 3-Nitrofluoranthene increases activity ISO Casp8 (Mus musculus) 6480464 3-nitrofluoranthene results in increased activity of CASP8 protein CTD PMID:19041363 3-nitropropanoic acid increases activity ISO Casp8 (Rattus norvegicus) 6480464 3-nitropropionic acid results in increased activity of CASP8 protein CTD PMID:15571979 3-phenylprop-2-enal increases activity EXP 6480464 cinnamaldehyde results in increased activity of CASP8 protein CTD PMID:15964311 4'-epidoxorubicin multiple interactions EXP 6480464 Epirubicin promotes the reaction [formononetin results in increased activity of CASP8 protein] and Epirubicin promotes the reaction [formononetin results in increased expression of CASP8 mRNA] CTD PMID:23867903 4,4'-sulfonyldiphenol increases activity ISO Casp8 (Rattus norvegicus) 6480464 bisphenol S results in increased activity of CASP8 protein CTD PMID:23458715 4,4'-sulfonyldiphenol increases expression ISO Casp8 (Mus musculus) 6480464 bisphenol S results in increased expression of CASP8 mRNA CTD PMID:30951980 4,5,6,7-TETRABROMOBENZOTRIAZOLE multiple interactions EXP 6480464 [4 more ... CTD PMID:16489027 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO Casp8 (Mus musculus) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CASP8 mRNA CTD PMID:21167638 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of CASP8 mRNA CTD PMID:12419474 4-hydroxyphenyl retinamide multiple interactions EXP 6480464 [Fenretinide co-treated with TNFSF10 protein] results in increased activity of CASP8 protein CTD PMID:17273769 4-nitro-m-cresol increases activity EXP 6480464 4-nitro-3-cresol results in increased activity of CASP8 protein CTD PMID:29307546 4-nitro-m-cresol increases activity ISO Casp8 (Mus musculus) 6480464 4-nitro-3-cresol results in increased activity of CASP8 protein CTD PMID:29307546 4-nitro-m-cresol multiple interactions EXP 6480464 CASP8 protein promotes the reaction [4-nitro-3-cresol results in increased expression of FAS mRNA] more ... CTD PMID:29307546 4-nonylphenol increases cleavage ISO Casp8 (Mus musculus) 6480464 4-nonylphenol results in increased cleavage of CASP8 protein CTD PMID:22056370 4-nonylphenol increases expression ISO Casp8 (Rattus norvegicus) 6480464 4-nonylphenol results in increased expression of CASP8 mRNA CTD PMID:30228064 4-nonylphenol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 4-nonylphenol affects the reaction [bisphenol A results in increased expression of CASP8 mRNA] and bisphenol A affects the reaction [4-nonylphenol results in increased expression of CASP8 mRNA] CTD PMID:30228064 4-nonylphenol decreases expression ISO Casp8 (Rattus norvegicus) 6480464 4-nonylphenol results in decreased expression of CASP8 mRNA CTD PMID:27087316 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased activity of CASP8 protein] CTD PMID:31364909 5-aminolevulinic acid increases activity EXP 6480464 Aminolevulinic Acid analog results in increased activity of CASP8 protein CTD PMID:21138480 5-aminolevulinic acid multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Aminolevulinic Acid analog results in increased activity of CASP8 protein] CTD PMID:21138480 5-aza-2'-deoxycytidine increases cleavage EXP 6480464 Decitabine results in increased cleavage of CASP8 protein CTD PMID:18636160 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 [[[Decitabine co-treated with IFNG protein] results in increased expression of CASP8 protein] which co-treated with TNFSF10 protein] results in increased activity of CASP8 protein more ... CTD PMID:16607283 more ... 5-aza-2'-deoxycytidine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Decitabine inhibits the reaction [Cadmium Chloride results in decreased cleavage of CASP8 protein] more ... CTD PMID:22457795 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of CASP8 mRNA and Decitabine results in increased expression of CASP8 protein CTD PMID:19214542 more ... 5-aza-2'-deoxycytidine decreases methylation EXP 6480464 Decitabine results in decreased methylation of CASP8 promoter CTD PMID:19440673 5-azacytidine increases expression EXP 6480464 Azacitidine results in increased expression of CASP8 mRNA CTD PMID:18082045 5-azacytidine increases expression ISO Casp8 (Mus musculus) 6480464 Azacitidine results in increased expression of CASP8 mRNA CTD PMID:23395740 5-fluorouracil multiple interactions EXP 6480464 [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CASP8 protein more ... CTD PMID:14607657 more ... 5-fluorouracil increases activity ISO Casp8 (Mus musculus) 6480464 Fluorouracil results in increased activity of CASP8 protein CTD PMID:32270916 5-fluorouracil increases cleavage EXP 6480464 Fluorouracil results in increased cleavage of CASP8 protein CTD PMID:19816940 and PMID:26544897 5-fluorouracil decreases expression EXP 6480464 Fluorouracil results in decreased expression of CASP8 mRNA CTD PMID:23941782 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of CASP8 mRNA and Fluorouracil results in increased expression of CASP8 protein CTD PMID:15585135 more ... 5-fluorouracil increases activity EXP 6480464 Fluorouracil results in increased activity of CASP8 protein CTD PMID:10779637 more ... 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases cleavage EXP 6480464 Omeprazole analog results in increased cleavage of CASP8 protein CTD PMID:18336733 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine multiple interactions EXP 6480464 4-cyclohexylmethoxy-5-nitrosopyrimidine-2 and 6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP8 protein] CTD PMID:26208482 6-bromoindirubin-3'-oxime multiple interactions EXP 6480464 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of CASP8 protein modified form] CTD PMID:28414160 6-formylpterin increases activity EXP 6480464 2-amino-4-hydroxy-6-formylpteridine results in increased activity of CASP8 protein CTD PMID:16019850 7-ketocholesterol increases activity ISO Casp8 (Rattus norvegicus) 6480464 7-ketocholesterol results in increased activity of CASP8 protein CTD PMID:25845326 7-ketocholesterol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 6-hydroxy-2 more ... CTD PMID:25845326 9'-cis-neoxanthin increases activity EXP 6480464 neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 9-cis-retinoic acid increases activity EXP 6480464 Alitretinoin results in increased activity of CASP8 protein CTD PMID:16449964 9-hydroxycanthin-6-one increases cleavage EXP 6480464 9-hydroxycanthin-6-one results in increased cleavage of CASP8 protein CTD PMID:29225138 9-Methoxycamptothecin increases activity EXP 6480464 9-methoxycamptothecin results in increased activity of CASP8 protein CTD PMID:23369935 ABT-737 multiple interactions EXP 6480464 3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]] more ... CTD PMID:20104024 ABT-737 increases cleavage EXP 6480464 ABT-737 results in increased cleavage of CASP8 protein CTD PMID:20104024 acetamide increases expression ISO Casp8 (Rattus norvegicus) 6480464 acetamide results in increased expression of CASP8 mRNA CTD PMID:31881176 acetylleucyl-leucyl-norleucinal multiple interactions ISO Casp8 (Mus musculus) 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein] CTD PMID:29111403 acetylsalicylic acid multiple interactions EXP 6480464 [Aspirin co-treated with TNFSF10 protein] results in increased activity of CASP8 protein more ... CTD PMID:15481331 more ... acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of CASP8 mRNA CTD PMID:20457246 acetylsalicylic acid increases activity EXP 6480464 Aspirin results in increased activity of CASP8 protein CTD PMID:11034327 aclacinomycin A increases activity EXP 6480464 Aclarubicin results in increased activity of CASP8 protein CTD PMID:20399885 acrolein affects activity EXP 6480464 Acrolein affects the activity of CASP8 protein CTD PMID:17222828 acrolein multiple interactions ISO Casp8 (Mus musculus) 6480464 capsazepine inhibits the reaction [Acrolein results in increased expression of CASP8 protein] and Glutathione inhibits the reaction [Acrolein results in increased expression of CASP8 protein] CTD PMID:24376112 acrolein increases expression ISO Casp8 (Mus musculus) 6480464 Acrolein results in increased expression of CASP8 protein CTD PMID:24376112 acrolein increases cleavage EXP 6480464 Acrolein results in increased cleavage of CASP8 protein CTD PMID:27238871 acrolein decreases activity ISO Casp8 (Mus musculus) 6480464 Acrolein results in decreased activity of CASP8 protein CTD PMID:11803030 acrolein multiple interactions EXP 6480464 Acrolein inhibits the reaction [FAS protein results in increased activity of CASP8 protein] more ... CTD PMID:17222828 and PMID:27238871 acrolein affects cleavage EXP 6480464 Acrolein affects the cleavage of CASP8 protein CTD PMID:17222828 acrolein affects alkylation EXP 6480464 Acrolein affects the alkylation of CASP8 protein CTD PMID:17222828 acrylamide increases expression ISO Casp8 (Rattus norvegicus) 6480464 Acrylamide results in increased expression of CASP8 mRNA CTD PMID:28959563 acrylamide decreases expression ISO Casp8 (Mus musculus) 6480464 Acrylamide results in decreased expression of CASP8 mRNA CTD PMID:35032568 actinomycin D decreases expression EXP 6480464 Dactinomycin results in decreased expression of CASP8 mRNA CTD PMID:16001973 adenosine increases activity EXP 6480464 Adenosine results in increased activity of CASP8 protein CTD PMID:17303086 adenosine increases activity ISO Casp8 (Rattus norvegicus) 6480464 Adenosine results in increased activity of CASP8 protein CTD PMID:16469385 adenosine multiple interactions EXP 6480464 Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP8 protein] CTD PMID:17303086 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CASP8 mRNA CTD PMID:27017951 more ... aflatoxin B1 increases expression ISO Casp8 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of CASP8 mRNA CTD PMID:28789997 aflatoxin B1 multiple interactions EXP 6480464 [Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA] more ... CTD PMID:27017951 and PMID:30668976 agomelatine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 agomelatine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP8 protein] CTD PMID:36356678 Ala-Gln multiple interactions EXP 6480464 alanylglutamine inhibits the reaction [tcdA protein and Clostridium difficile results in increased activity of CASP8 protein] CTD PMID:16368960 alantolactone increases cleavage EXP 6480464 alantolactone results in increased cleavage of CASP8 protein CTD PMID:22721982 alborixin increases activity EXP 6480464 alborixin results in increased activity of CASP8 protein CTD PMID:27378626 aldehydo-D-glucose increases activity ISO Casp8 (Mus musculus) 6480464 Glucose results in increased activity of CASP8 protein CTD PMID:18973755 aldehydo-D-glucose multiple interactions EXP 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA and Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA] CTD PMID:33962019 aldehydo-D-glucose multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8] CTD PMID:18791325 aldehydo-D-glucose increases activity ISO Casp8 (Rattus norvegicus) 6480464 Glucose results in increased activity of CASP8 CTD PMID:18791325 alginic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 Alginic Acid results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:35066102 all-trans-acitretin increases activity EXP 6480464 Acitretin results in increased activity of CASP8 protein CTD PMID:18624760 all-trans-neoxanthin increases activity EXP 6480464 neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 all-trans-retinoic acid multiple interactions EXP 6480464 [Tretinoin co-treated with Paclitaxel] results in increased cleavage of CASP8 protein more ... CTD PMID:16242776 and PMID:18098270 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of CASP8 mRNA CTD PMID:33167477 all-trans-retinoic acid increases cleavage EXP 6480464 Tretinoin results in increased cleavage of CASP8 protein CTD PMID:16135400 Aloe emodin increases activity EXP 6480464 aloe emodin results in increased activity of CASP8 protein CTD PMID:19928967 Aloe emodin multiple interactions EXP 6480464 [Fluorouracil co-treated with aloe emodin] affects the expression of CASP8 and Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP8 protein modified form] CTD PMID:19928967 Aloe emodin increases expression EXP 6480464 aloe emodin results in increased expression of CASP8 protein modified form CTD PMID:19928967 alpha-mangostin increases activity EXP 6480464 mangostin results in increased activity of CASP8 protein CTD PMID:24480042 alpha-naphthoflavone increases activity ISO Casp8 (Mus musculus) 6480464 alpha-naphthoflavone results in increased activity of CASP8 protein CTD PMID:18334599 alvocidib multiple interactions EXP 6480464 [alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP8 protein more ... CTD PMID:12231544 more ... alvocidib increases cleavage EXP 6480464 alvocidib results in increased cleavage of CASP8 protein CTD PMID:10896673 and PMID:12589031 amiloride multiple interactions EXP 6480464 Amiloride promotes the reaction [TNFSF10 protein results in increased activity of CASP8 protein] and Amiloride promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein] CTD PMID:15607733 and PMID:16059913 amiodarone multiple interactions EXP 6480464 [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein CTD PMID:21292685 amiodarone increases expression ISO Casp8 (Rattus norvegicus) 6480464 Amiodarone results in increased expression of CASP8 protein modified form CTD PMID:21224497 amlodipine multiple interactions EXP 6480464 [Amlodipine co-treated with Topotecan] results in increased activity of CASP8 protein CTD PMID:16516327 ammonium chloride affects expression ISO Casp8 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of CASP8 mRNA CTD PMID:16483693 ammonium chloride increases expression ISO Casp8 (Rattus norvegicus) 6480464 Ammonium Chloride results in increased expression of CASP8 protein CTD PMID:16483693 ammonium chloride increases activity ISO Casp8 (Rattus norvegicus) 6480464 Ammonium Chloride results in increased activity of CASP8 protein CTD PMID:18722528 amphibole asbestos increases expression EXP 6480464 Asbestos and Amphibole results in increased expression of CASP8 protein CTD PMID:20855422 andrographolide multiple interactions EXP 6480464 [andrographolide co-treated with Cisplatin] results in increased expression of CASP8 mRNA more ... CTD PMID:19097688 and PMID:24563380 andrographolide increases expression EXP 6480464 andrographolide results in increased expression of CASP8 mRNA CTD PMID:24563380 andrographolide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 andrographolide inhibits the reaction [Copper Sulfate results in increased activity of CASP8 protein] CTD PMID:20946909 andrographolide increases activity EXP 6480464 andrographolide results in increased activity of CASP8 protein CTD PMID:19097688 anthocyanin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein] CTD PMID:28856781 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [6-(N more ... CTD PMID:15501958 more ... antimycin A increases cleavage EXP 6480464 Antimycin A results in increased cleavage of CASP8 protein CTD PMID:32662599 antimycin A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP8 protein] CTD PMID:32662599 antirheumatic drug decreases expression EXP 6480464 Antirheumatic Agents results in decreased expression of CASP8 mRNA CTD PMID:24449571 apigenin increases cleavage EXP 6480464 Apigenin results in increased cleavage of CASP8 protein CTD PMID:15486995 apigenin multiple interactions EXP 6480464 [TNFSF10 protein results in increased susceptibility to Apigenin] which results in increased cleavage of CASP8 protein CTD PMID:29247770 apigenin increases activity ISO Casp8 (Rattus norvegicus) 6480464 Apigenin results in increased activity of CASP8 protein CTD PMID:24144774 apigenin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP8 protein] more ... CTD PMID:24144774 and PMID:30152906 arachidonic acid increases activity EXP 6480464 Arachidonic Acid results in increased activity of CASP8 protein CTD PMID:19720122 arachidonic acid multiple interactions EXP 6480464 FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP8 protein] CTD PMID:19720122 arecoline increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Arecoline results in increased cleavage of CASP8 protein CTD PMID:33929070 arjunolic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 arjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of CASP8 protein] CTD PMID:21420465 Aroclor 1254 decreases expression ISO Casp8 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CASP8 mRNA CTD PMID:23650126 arsane affects methylation EXP 6480464 Arsenic affects the methylation of CASP8 gene CTD PMID:25304211 arsane multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased cleavage of CASP8 protein and ATF3 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased cleavage of CASP8 protein] CTD PMID:33921748 arsane increases expression EXP 6480464 Arsenic results in increased expression of CASP8 mRNA CTD PMID:27838757 arsenic atom affects methylation EXP 6480464 Arsenic affects the methylation of CASP8 gene CTD PMID:25304211 arsenic atom multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased cleavage of CASP8 protein and ATF3 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased cleavage of CASP8 protein] CTD PMID:33921748 arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of CASP8 mRNA CTD PMID:27838757 arsenous acid multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of CASP8 mRNA more ... CTD PMID:16174796 more ... arsenous acid increases cleavage EXP 6480464 Arsenic Trioxide results in increased cleavage of CASP8 protein CTD PMID:18491231 more ... arsenous acid increases activity ISO Casp8 (Mus musculus) 6480464 Arsenic Trioxide results in increased activity of CASP8 protein CTD PMID:21565247 and PMID:25410152 arsenous acid increases activity EXP 6480464 Arsenic Trioxide results in increased activity of CASP8 protein CTD PMID:10721769 more ... arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CASP8 mRNA more ... CTD PMID:20953137 more ... arsenous acid multiple interactions ISO Casp8 (Mus musculus) 6480464 Arsenic Trioxide promotes the reaction [Drugs and Chinese Herbal results in increased cleavage of CASP8 protein] CTD PMID:28587418 arsenous acid affects activity EXP 6480464 Arsenic Trioxide affects the activity of CASP8 protein CTD PMID:16010437 asarone increases activity EXP 6480464 asarone results in increased activity of CASP8 protein CTD PMID:29174417 atorvastatin calcium multiple interactions EXP 6480464 [Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP8 protein CTD PMID:18172863 atorvastatin calcium multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein] and [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of CASP8 protein] CTD PMID:20946910 atorvastatin calcium increases activity EXP 6480464 Atorvastatin results in increased activity of CASP8 protein CTD PMID:15705602 atrazine multiple interactions ISO Casp8 (Mus musculus) 6480464 Melatonin inhibits the reaction [Atrazine results in increased cleavage of CASP8 protein] CTD PMID:25259610 atrazine increases cleavage ISO Casp8 (Mus musculus) 6480464 Atrazine results in increased cleavage of CASP8 protein CTD PMID:25259610 auranofin multiple interactions EXP 6480464 Auranofin results in decreased expression of and results in increased cleavage of CASP8 protein CTD PMID:20542334 Auriculasin multiple interactions EXP 6480464 [auriculasin co-treated with TNFSF10 protein] results in increased expression of CASP8 protein and TNFRSF10B protein affects the reaction [[auriculasin co-treated with TNFSF10 protein] results in increased expression of CASP8 protein] CTD PMID:30817944 azadirachtin A increases expression EXP 6480464 azadirachtin results in increased expression of CASP8 protein CTD PMID:20429769 azadiradione increases activity EXP 6480464 azadiradione results in increased activity of CASP8 protein CTD PMID:21381696 bafilomycin A1 multiple interactions ISO Casp8 (Mus musculus) 6480464 bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein] CTD PMID:29111403 bafilomycin A1 multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein] CTD PMID:28378122 baicalein multiple interactions ISO Casp8 (Mus musculus) 6480464 baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP8 protein modified form] CTD PMID:20850421 BAPTA multiple interactions ISO Casp8 (Mus musculus) 6480464 1 more ... CTD PMID:29111403 Bardoxolone methyl decreases expression EXP 6480464 bardoxolone methyl results in decreased expression of CASP8 protein CTD PMID:25246272 bathocuproine disulfonic acid multiple interactions EXP 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] and bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]] CTD PMID:15477007 beauvericin increases expression EXP 6480464 beauvericin results in increased expression of CASP8 mRNA CTD PMID:29203277 belinostat increases expression EXP 6480464 belinostat results in increased expression of CASP8 mRNA CTD PMID:26272509 belinostat multiple interactions EXP 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CASP8 mRNA CTD PMID:27188386 bellidifolin increases expression EXP 6480464 bellidifolin results in increased expression of CASP8 protein CTD PMID:33299414 benzalkonium chloride decreases expression EXP 6480464 Benzalkonium Compounds results in decreased expression of CASP8 mRNA CTD PMID:28236482 benzene increases expression ISO Casp8 (Rattus norvegicus) 6480464 Benzene results in increased expression of CASP8 protein CTD PMID:17171516 benzene-1,2,4-triol increases activity EXP 6480464 hydroxyhydroquinone results in increased activity of CASP8 protein CTD PMID:23776099 benzo[a]pyrene increases cleavage EXP 6480464 Benzo(a)pyrene results in increased cleavage of CASP8 protein CTD PMID:16041517 benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of CASP8 promoter CTD PMID:27901495 benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of CASP8 5' UTR CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of CASP8 mRNA CTD PMID:24239969 benzo[a]pyrene increases expression ISO Casp8 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of CASP8 mRNA CTD PMID:22228805 benzo[a]pyrene increases activity ISO Casp8 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased activity of CASP8 protein CTD PMID:22051199 benzo[a]pyrene multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP8 protein] CTD PMID:22051199 benzo[a]pyrene decreases expression ISO Casp8 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of CASP8 mRNA CTD PMID:19770486 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein more ... CTD PMID:16041517 and PMID:22951985 benzo[a]pyrene diol epoxide I increases cleavage EXP 6480464 7 more ... CTD PMID:21983885 benzo[e]pyrene increases activity EXP 6480464 benzo(e)pyrene results in increased activity of CASP8 protein CTD PMID:18586875 benzo[e]pyrene increases activity ISO Casp8 (Rattus norvegicus) 6480464 benzo(e)pyrene results in increased activity of CASP8 protein CTD PMID:19899995 benzophenanthridine increases activity EXP 6480464 Benzophenanthridines analog results in increased activity of CASP8 protein CTD PMID:23117580 berberine increases activity EXP 6480464 Berberine results in increased activity of CASP8 protein CTD PMID:20656010 beta-hexachlorocyclohexane increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 beta-hexachlorocyclohexane results in increased cleavage of CASP8 protein CTD PMID:19760616 Beta-Solamarine multiple interactions EXP 6480464 beta-solamarine promotes the reaction [Cisplatin results in increased activity of CASP8 protein] CTD PMID:17619073 Beta-Solamarine increases activity EXP 6480464 beta-solamarine results in increased activity of CASP8 protein CTD PMID:17619073 betulin increases cleavage EXP 6480464 betulin results in increased cleavage of CASP8 protein CTD PMID:32190974 betulinic acid increases activity EXP 6480464 Betulinic Acid results in increased activity of CASP8 protein CTD PMID:26772157 and PMID:29454615 bifenthrin increases activity ISO Casp8 (Mus musculus) 6480464 bifenthrin results in increased activity of CASP8 protein CTD PMID:26071804 bifenthrin decreases expression ISO Casp8 (Mus musculus) 6480464 bifenthrin results in decreased expression of CASP8 mRNA CTD PMID:26071804 bis(2-chloroethyl) sulfide multiple interactions EXP 6480464 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Mustard Gas results in increased activity of CASP8 protein] more ... CTD PMID:12482751 more ... bis(2-chloroethyl) sulfide increases activity EXP 6480464 Mustard Gas results in increased activity of CASP8 protein CTD PMID:16738803 and PMID:20226831 bis(2-chloroethyl) sulfide increases expression ISO Casp8 (Mus musculus) 6480464 Mustard Gas results in increased expression of CASP8 mRNA CTD PMID:18955075 bis(2-ethylhexyl) phthalate increases activity EXP 6480464 Diethylhexyl Phthalate results in increased activity of CASP8 protein CTD PMID:22155658 bis(2-ethylhexyl) phthalate decreases expression ISO Casp8 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of CASP8 mRNA CTD PMID:31211961 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of CASP8 mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein more ... CTD PMID:28013214 more ... bis(2-ethylhexyl) phthalate increases expression ISO Casp8 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of CASP8 mRNA CTD PMID:25701202 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CASP8 protein CTD PMID:21277958 bisphenol A multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of CASP8 protein CTD PMID:35739755 and PMID:37364641 bisphenol A increases activity EXP 6480464 bisphenol A results in increased activity of CASP8 protein CTD PMID:30036487 and PMID:30841469 bisphenol A increases activity ISO Casp8 (Mus musculus) 6480464 bisphenol A results in increased activity of CASP8 protein CTD PMID:31387175 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CASP8 mRNA and bisphenol A results in increased expression of CASP8 protein CTD PMID:29275510 more ... bisphenol A increases expression ISO Casp8 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of CASP8 mRNA CTD PMID:27539358 and PMID:30228064 bisphenol A decreases expression ISO Casp8 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of CASP8 mRNA CTD PMID:25181051 bisphenol A increases expression ISO Casp8 (Mus musculus) 6480464 bisphenol A results in increased expression of CASP8 mRNA and bisphenol A results in increased expression of CASP8 protein CTD PMID:23900028 more ... bisphenol A multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 4-nonylphenol affects the reaction [bisphenol A results in increased expression of CASP8 mRNA] more ... CTD PMID:25454643 and PMID:30228064 bisphenol A increases activity ISO Casp8 (Rattus norvegicus) 6480464 bisphenol A results in increased activity of CASP8 protein CTD PMID:25454643 bisphenol A affects expression ISO Casp8 (Mus musculus) 6480464 bisphenol A affects the expression of CASP8 mRNA CTD PMID:26049153 and PMID:26746108 Bisphenol A glycidylmethacrylate multiple interactions ISO Casp8 (Mus musculus) 6480464 wogonin inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP8 protein] CTD PMID:26756871 Bisphenol A glycidylmethacrylate increases activity ISO Casp8 (Mus musculus) 6480464 Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP8 protein CTD PMID:26756871 bisphenol F increases expression ISO Casp8 (Mus musculus) 6480464 bisphenol F results in increased expression of CASP8 mRNA CTD PMID:30951980 and PMID:31453682 bisphenol F increases activity EXP 6480464 bisphenol F results in increased activity of CASP8 protein CTD PMID:33916708 bleomycin A2 multiple interactions EXP 6480464 [Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA and [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA CTD PMID:26800624 borrelidin increases activity EXP 6480464 borrelidin results in increased activity of CASP8 protein CTD PMID:14563161 bortezomib multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of CASP8 mRNA more ... CTD PMID:12393500 more ... bortezomib increases cleavage EXP 6480464 Bortezomib results in increased cleavage of CASP8 protein CTD PMID:12393500 more ... Brevetoxin B increases activity EXP 6480464 brevetoxin 2 results in increased activity of CASP8 protein CTD PMID:19536525 bromoacetate decreases expression EXP 6480464 bromoacetate results in decreased expression of CASP8 mRNA CTD PMID:19753638 bromoacetate increases expression EXP 6480464 bromoacetate results in increased expression of CASP8 mRNA CTD PMID:19753638 Brusatol increases cleavage EXP 6480464 brusatol results in increased cleavage of CASP8 protein CTD PMID:33465425 bupropion increases activity EXP 6480464 Bupropion results in increased activity of CASP8 protein CTD PMID:21354251 busulfan increases activity EXP 6480464 Busulfan results in increased activity of CASP8 protein CTD PMID:18339423 busulfan multiple interactions EXP 6480464 [decitabine co-treated with Busulfan] results in increased activity of CASP8 protein and pifithrin inhibits the reaction [[decitabine co-treated with Busulfan] results in increased activity of CASP8 protein] CTD PMID:19732952 butein increases activity EXP 6480464 butein results in increased activity of CASP8 protein CTD PMID:35130734 Butylbenzyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein more ... CTD PMID:28013214 more ... Butylparaben increases expression EXP 6480464 butylparaben results in increased expression of CASP8 protein CTD PMID:24481588 cadmium atom multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 agomelatine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP8 protein] and Cadmium inhibits the reaction [TNF protein results in increased cleavage of and results in increased activity of CASP8 protein] CTD PMID:16263807 and PMID:36356678 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of CASP8 mRNA CTD PMID:27687512 cadmium atom increases cleavage ISO Casp8 (Mus musculus) 6480464 Cadmium results in increased cleavage of CASP8 protein CTD PMID:29111403 cadmium atom multiple interactions ISO Casp8 (Mus musculus) 6480464 1 more ... CTD PMID:29111403 cadmium dichloride multiple interactions ISO Casp8 (Mus musculus) 6480464 [Mercuric Chloride co-treated with sodium arsenite co-treated with Cadmium Chloride] results in increased activity of CASP8 protein more ... CTD PMID:16421179 more ... cadmium dichloride decreases expression ISO Casp8 (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of CASP8 protein CTD PMID:35844137 cadmium dichloride decreases response to substance EXP 6480464 CASP8 results in decreased susceptibility to Cadmium Chloride CTD PMID:25448810 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of CASP8 promoter CTD PMID:25448810 cadmium dichloride increases activity EXP 6480464 Cadmium Chloride results in increased activity of CASP8 protein CTD PMID:21697648 and PMID:23485651 cadmium dichloride increases activity ISO Casp8 (Mus musculus) 6480464 Cadmium Chloride results in increased activity of CASP8 protein CTD PMID:16421179 and PMID:21252392 cadmium dichloride decreases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased cleavage of CASP8 protein CTD PMID:22457795 cadmium dichloride decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of CASP8 protein CTD PMID:22457795 cadmium dichloride increases methylation ISO Casp8 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased methylation of CASP8 promoter CTD PMID:22457795 cadmium dichloride multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 agomelatine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP8 protein] more ... CTD PMID:16263807 more ... cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CASP8 protein more ... CTD PMID:23941782 more ... cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of CASP8 mRNA CTD PMID:19426795 more ... cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CASP8 mRNA and Cadmium Chloride results in increased expression of CASP8 protein CTD PMID:12160620 more ... cadmium dichloride increases expression ISO Casp8 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of CASP8 protein CTD PMID:21420465 and PMID:28342888 cadmium sulfide decreases expression EXP 6480464 cadmium sulfide results in decreased expression of CASP8 mRNA CTD PMID:27866839 caffeine increases phosphorylation EXP 6480464 Caffeine results in increased phosphorylation of CASP8 protein CTD PMID:35688186 Calcimycin increases activity EXP 6480464 Calcimycin results in increased activity of CASP8 protein CTD PMID:25410152 Calcimycin increases activity ISO Casp8 (Mus musculus) 6480464 Calcimycin results in increased activity of CASP8 protein CTD PMID:25410152 calcitriol multiple interactions EXP 6480464 [Calcitriol co-treated with Gemcitabine] results in increased expression of CASP8 protein CTD PMID:20699664 calcitriol affects expression ISO Casp8 (Mus musculus) 6480464 Calcitriol affects the expression of CASP8 mRNA CTD PMID:15138306 Calpeptin multiple interactions ISO Casp8 (Mus musculus) 6480464 calpeptin inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein] CTD PMID:29111403 camptothecin multiple interactions EXP 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:15475000 more ... camptothecin decreases expression EXP 6480464 Camptothecin results in decreased expression of CASP8 mRNA CTD PMID:30581319 camptothecin increases expression EXP 6480464 Camptothecin results in increased expression of CASP8 protein CTD PMID:30885713 camptothecin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Naphthoquinones analog inhibits the reaction [Camptothecin results in increased activity of CASP8 protein] CTD PMID:19497415 camptothecin increases activity EXP 6480464 Camptothecin results in increased activity of CASP8 protein CTD PMID:15475000 and PMID:34635930 camptothecin affects cleavage EXP 6480464 Camptothecin affects the cleavage of CASP8 protein CTD PMID:10896673 cannabidiol decreases expression ISO Casp8 (Mus musculus) 6480464 Cannabidiol results in decreased expression of CASP8 mRNA CTD PMID:33019509 cannabidiol increases cleavage EXP 6480464 Cannabidiol results in increased cleavage of CASP8 protein CTD PMID:31699976 cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of CASP8 mRNA CTD PMID:27932991 and PMID:31801206 cannabidiol multiple interactions EXP 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of CASP8 mRNA CTD PMID:30096889 cannabigerol decreases expression ISO Casp8 (Mus musculus) 6480464 cannabigerol results in decreased expression of CASP8 mRNA CTD PMID:33019509 cantharidic acid multiple interactions EXP 6480464 SB 203580 inhibits the reaction [cantharidic acid results in increased cleavage of CASP8 protein] CTD PMID:29159945 and PMID:31916385 cantharidic acid increases cleavage EXP 6480464 cantharidic acid results in increased cleavage of CASP8 protein CTD PMID:29159945 more ... cantharidin multiple interactions EXP 6480464 Cantharidin results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:27113412 capsaicin multiple interactions EXP 6480464 [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein more ... CTD PMID:19846903 more ... capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of CASP8 mRNA CTD PMID:19502594 capsaicin increases activity EXP 6480464 Capsaicin results in increased activity of CASP8 protein CTD PMID:19502594 capsaicin decreases expression EXP 6480464 Capsaicin results in decreased expression of CASP8 protein CTD PMID:19846903 capsazepine multiple interactions ISO Casp8 (Mus musculus) 6480464 capsazepine inhibits the reaction [Acrolein results in increased expression of CASP8 protein] CTD PMID:24376112 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of CASP8 mRNA CTD PMID:24752500 carbon atom multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA CTD PMID:31268311 carbon monoxide increases activity ISO Casp8 (Rattus norvegicus) 6480464 Carbon Monoxide results in increased activity of CASP8 protein CTD PMID:25562542 carbon monoxide multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA CTD PMID:31268311 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:23634900 and PMID:32493873 carbon nanotube increases expression ISO Casp8 (Rattus norvegicus) 6480464 Nanotubes and Carbon results in increased expression of CASP8 mRNA CTD PMID:30605223 carbon nanotube increases activity ISO Casp8 (Rattus norvegicus) 6480464 Nanotubes and Carbon analog results in increased activity of CASP8 protein CTD PMID:19827037 carbon nanotube increases expression ISO Casp8 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 carbonyl cyanide p-trifluoromethoxyphenylhydrazone decreases expression EXP 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CASP8 mRNA CTD PMID:16039398 carnosic acid increases cleavage EXP 6480464 salvin results in increased cleavage of CASP8 protein CTD PMID:28918123 carnosic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP8 protein] CTD PMID:29854073 carnosic acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP8 protein] CTD PMID:28918123 carnosine multiple interactions ISO Casp8 (Mus musculus) 6480464 Carnosine inhibits the reaction [Cisplatin results in increased cleavage of CASP8 protein] CTD PMID:29191451 casticin multiple interactions EXP 6480464 casticin results in increased cleavage of and results in increased activity of CASP8 protein and casticin results in increased expression of and results in increased activity of CASP8 protein CTD PMID:27862857 and PMID:29098808 catechol increases activity EXP 6480464 catechol results in increased activity of CASP8 protein CTD PMID:23776099 celastrol increases cleavage EXP 6480464 celastrol results in increased cleavage of CASP8 protein CTD PMID:21466843 celastrol decreases expression EXP 6480464 celastrol results in decreased expression of CASP8 mRNA CTD PMID:27374097 celecoxib increases activity EXP 6480464 Celecoxib analog results in increased activity of CASP8 protein and Celecoxib results in increased activity of CASP8 protein CTD PMID:12824303 and PMID:15499625 celecoxib increases cleavage EXP 6480464 Celecoxib results in increased cleavage of CASP8 protein CTD PMID:20104024 celecoxib multiple interactions EXP 6480464 3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]] more ... CTD PMID:15197583 more ... cerivastatin increases activity EXP 6480464 cerivastatin results in increased activity of CASP8 protein CTD PMID:15705602 ceruletide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Ceruletide results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:16339139 chalcone increases cleavage EXP 6480464 Chalcone results in increased cleavage of CASP8 protein CTD PMID:20620131 chalcone multiple interactions EXP 6480464 MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP8 protein] CTD PMID:20620131 chalcones multiple interactions EXP 6480464 BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of and results in increased activity of CASP8 protein] and Chalcones analog results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:30576621 chalcones increases expression EXP 6480464 Chalcones analog results in increased expression of CASP8 mRNA CTD PMID:32856275 chlorambucil increases activity EXP 6480464 Chlorambucil results in increased activity of CASP8 protein CTD PMID:11675354 chloroacetaldehyde decreases activity EXP 6480464 chloroacetaldehyde results in decreased activity of CASP8 protein CTD PMID:17035713 chlorogenic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 Chlorogenic Acid inhibits the reaction [aluminum chloride results in increased expression of CASP8 protein] CTD PMID:28623112 chloroquine increases cleavage EXP 6480464 Chloroquine results in increased cleavage of CASP8 protein CTD PMID:27692344 and PMID:28906492 chloroquine multiple interactions EXP 6480464 Chloroquine promotes the reaction [fosbretabulin results in increased cleavage of CASP8 protein] CTD PMID:28906492 chloroquine multiple interactions ISO Casp8 (Mus musculus) 6480464 Chloroquine inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein] CTD PMID:29111403 chlorothalonil increases expression EXP 6480464 tetrachloroisophthalonitrile results in increased expression of CASP8 mRNA CTD PMID:34549778 chlorpyrifos decreases expression ISO Casp8 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of CASP8 mRNA CTD PMID:32715474 chlorpyrifos increases expression ISO Casp8 (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of CASP8 protein CTD PMID:30990955 chlorpyrifos multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Chlorpyrifos results in increased expression of CASP8 protein] CTD PMID:30990955 chlorpyrifos multiple interactions EXP 6480464 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 mRNA and [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 protein CTD PMID:32800223 cholesterol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 6-hydroxy-2 more ... CTD PMID:19477266 and PMID:20946910 cholesterol increases expression ISO Casp8 (Rattus norvegicus) 6480464 Cholesterol analog results in increased expression of CASP8 mRNA and Cholesterol results in increased expression of CASP8 protein CTD PMID:19477266 and PMID:20946910 cholesterol increases activity ISO Casp8 (Rattus norvegicus) 6480464 Cholesterol analog results in increased activity of CASP8 protein CTD PMID:19477266 choline multiple interactions ISO Casp8 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CASP8 gene CTD PMID:20938992 chromium atom increases expression ISO Casp8 (Rattus norvegicus) 6480464 Chromium results in increased expression of CASP8 mRNA CTD PMID:17692352 chromium(3+) trichloride multiple interactions EXP 6480464 chromic chloride results in increased expression of and results in increased activity of CASP8 protein CTD PMID:14741615 chromium(6+) increases expression EXP 6480464 chromium hexavalent ion results in increased expression of CASP8 mRNA CTD PMID:27793765 chromone increases expression EXP 6480464 4-chromone analog results in increased expression of CASP8 protein modified form CTD PMID:30256521 chromone multiple interactions EXP 6480464 benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [4-chromone analog results in increased expression of CASP8 protein modified form] CTD PMID:30256521 chrysazin multiple interactions EXP 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [danthron results in increased activity of CASP8 protein] and danthron results in increased activity of and results in increased expression of CASP8 protein CTD PMID:21126053 chrysazin increases expression EXP 6480464 danthron results in increased expression of CASP8 mRNA CTD PMID:21126053 chrysin multiple interactions EXP 6480464 [Cisplatin co-treated with chrysin] results in increased cleavage of CASP8 protein more ... CTD PMID:20457140 more ... chrysin increases cleavage EXP 6480464 chrysin results in increased cleavage of CASP8 protein CTD PMID:25770930 ciglitazone multiple interactions EXP 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased activity of CASP8 protein]] more ... CTD PMID:21067863 ciglitazone increases activity EXP 6480464 ciglitazone results in increased activity of CASP8 protein CTD PMID:21067863 cilostazol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 cilostazol inhibits the reaction [Nitroprusside results in increased activity of CASP8 protein] CTD PMID:18311796 cimetidine increases activity EXP 6480464 Cimetidine results in increased activity of CASP8 protein CTD PMID:17273750 and PMID:20127008 Cinobufotalin increases cleavage EXP 6480464 cinobufotalin results in increased cleavage of CASP8 protein CTD PMID:22898211 ciprofloxacin increases activity EXP 6480464 Ciprofloxacin results in increased activity of CASP8 protein CTD PMID:11875713 cisplatin multiple interactions EXP 6480464 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Cisplatin results in increased activity of CASP8 protein]] more ... CTD PMID:16803524 more ... cisplatin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 tranilast inhibits the reaction [Cisplatin results in increased expression of CASP8 protein] CTD PMID:34047436 cisplatin increases expression ISO Casp8 (Mus musculus) 6480464 Cisplatin results in increased expression of CASP8 mRNA CTD PMID:26546572 cisplatin multiple interactions ISO Casp8 (Mus musculus) 6480464 4-methyl-N1-(3-phenylpropyl)benzene-1 more ... CTD PMID:26546572 and PMID:29191451 cisplatin increases activity EXP 6480464 Cisplatin results in increased activity of CASP8 protein CTD PMID:16009487 more ... cisplatin increases cleavage ISO Casp8 (Mus musculus) 6480464 Cisplatin results in increased cleavage of CASP8 protein CTD PMID:29191451 cisplatin increases cleavage EXP 6480464 Cisplatin results in increased cleavage of CASP8 protein CTD PMID:17021654 more ... cisplatin increases expression ISO Casp8 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of CASP8 protein CTD PMID:21525749 and PMID:34047436 cisplatin increases activity ISO Casp8 (Mus musculus) 6480464 Cisplatin results in increased activity of CASP8 protein CTD PMID:21526214 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of CASP8 mRNA and Cisplatin results in increased expression of CASP8 protein CTD PMID:16803524 more ... cisplatin decreases response to substance EXP 6480464 CASP8 protein mutant form results in decreased susceptibility to Cisplatin CTD PMID:21801448 cladribine multiple interactions EXP 6480464 [Valproic Acid co-treated with Cladribine] results in increased cleavage of CASP8 protein more ... CTD PMID:12948851 more ... cladribine increases activity EXP 6480464 Cladribine results in increased activity of CASP8 protein CTD PMID:11672427 more ... cladribine increases cleavage EXP 6480464 Cladribine results in increased cleavage of CASP8 protein CTD PMID:15516989 clavulone II multiple interactions EXP 6480464 clavulone II results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15920677 clofibrate increases expression ISO Casp8 (Mus musculus) 6480464 Clofibrate results in increased expression of CASP8 mRNA CTD PMID:23811191 clomipramine increases activity ISO Casp8 (Mus musculus) 6480464 Clomipramine results in increased activity of CASP8 protein CTD PMID:28482088 clonidine increases activity EXP 6480464 Clonidine results in increased activity of CASP8 protein CTD PMID:28115640 clonidine (amino form) increases activity EXP 6480464 Clonidine results in increased activity of CASP8 protein CTD PMID:28115640 clonidine (imino form) increases activity EXP 6480464 Clonidine results in increased activity of CASP8 protein CTD PMID:28115640 clotrimazole multiple interactions ISO Casp8 (Mus musculus) 6480464 [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP8 protein] and Clotrimazole inhibits the reaction [lead acetate results in increased activity of CASP8 protein] CTD PMID:22033380 cobalt dichloride increases activity EXP 6480464 cobaltous chloride results in increased activity of CASP8 protein CTD PMID:16374551 cobalt dichloride affects activity ISO Casp8 (Mus musculus) 6480464 cobaltous chloride affects the activity of CASP8 protein CTD PMID:23684559 cocaine affects expression ISO Casp8 (Mus musculus) 6480464 Cocaine affects the expression of CASP8 mRNA CTD PMID:15681117 cocaine increases activity ISO Casp8 (Rattus norvegicus) 6480464 Cocaine results in increased activity of CASP8 protein CTD PMID:11392460 and PMID:18974856 coenzyme Q10 multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of CASP8 protein] CTD PMID:27087047 colistin increases cleavage ISO Casp8 (Mus musculus) 6480464 Colistin results in increased cleavage of CASP8 protein CTD PMID:34560125 conjugated linoleic acid increases expression ISO Casp8 (Mus musculus) 6480464 Linoleic Acids and Conjugated results in increased expression of CASP8 protein CTD PMID:20155912 copper atom multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in increased cleavage of CASP8 protein and [Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of CASP8 protein CTD PMID:22276220 copper atom multiple interactions ISO Casp8 (Mus musculus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP8 mRNA and [Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP8 protein CTD PMID:31491480 copper atom increases expression ISO Casp8 (Rattus norvegicus) 6480464 Copper deficiency results in increased expression of CASP8 mRNA and Copper results in increased expression of CASP8 protein CTD PMID:17418555 and PMID:30556269 copper atom increases expression ISO Casp8 (Mus musculus) 6480464 Copper analog results in increased expression of CASP8 protein CTD PMID:22000994 copper atom multiple interactions EXP 6480464 [Ditiocarb binds to Copper] which results in increased activity of CASP8 protein and [Thiosemicarbazones binds to Copper] which results in decreased activity of CASP8 protein CTD PMID:20931265 and PMID:22951949 copper(0) multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in increased cleavage of CASP8 protein and [Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of CASP8 protein CTD PMID:22276220 copper(0) multiple interactions ISO Casp8 (Mus musculus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP8 mRNA and [Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP8 protein CTD PMID:31491480 copper(0) increases expression ISO Casp8 (Rattus norvegicus) 6480464 Copper deficiency results in increased expression of CASP8 mRNA and Copper results in increased expression of CASP8 protein CTD PMID:17418555 and PMID:30556269 copper(0) increases expression ISO Casp8 (Mus musculus) 6480464 Copper analog results in increased expression of CASP8 protein CTD PMID:22000994 copper(0) multiple interactions EXP 6480464 [Ditiocarb binds to Copper] which results in increased activity of CASP8 protein and [Thiosemicarbazones binds to Copper] which results in decreased activity of CASP8 protein CTD PMID:20931265 and PMID:22951949 copper(II) chloride increases expression ISO Casp8 (Mus musculus) 6480464 cupric chloride results in increased expression of CASP8 protein CTD PMID:23313662 copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of CASP8 mRNA CTD PMID:19549813 copper(II) sulfate multiple interactions ISO Casp8 (Mus musculus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP8 mRNA and [Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP8 protein CTD PMID:31491480 copper(II) sulfate multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 andrographolide inhibits the reaction [Copper Sulfate results in increased activity of CASP8 protein] more ... CTD PMID:20946909 and PMID:33127410 cordycepin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP8 protein] CTD PMID:21310227 cordycepin increases expression EXP 6480464 cordycepin results in increased expression of CASP8 protein CTD PMID:23941773 cordycepin increases activity EXP 6480464 cordycepin results in increased activity of CASP8 protein CTD PMID:21310227 corticosterone increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Corticosterone results in increased cleavage of CASP8 protein CTD PMID:29625166 corticosterone multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Estradiol inhibits the reaction [Corticosterone results in increased cleavage of CASP8 protein] more ... CTD PMID:29625166 coumarin increases expression EXP 6480464 coumarin analog results in increased expression of CASP8 mRNA CTD PMID:32578917 crizotinib increases cleavage EXP 6480464 Crizotinib results in increased cleavage of CASP8 protein CTD PMID:31706006 crocidolite asbestos multiple interactions EXP 6480464 Asbestos more ... CTD PMID:22608188 crocidolite asbestos increases expression EXP 6480464 Asbestos more ... CTD PMID:23634900 crocidolite asbestos increases activity EXP 6480464 Asbestos and Crocidolite results in increased activity of CASP8 protein CTD PMID:22608188 crocin-1 increases activity EXP 6480464 crocin results in increased activity of CASP8 protein CTD PMID:32886819 cucurbitacin I increases cleavage EXP 6480464 cucurbitacin I results in increased cleavage of CASP8 protein CTD PMID:24858077 curcumin increases activity EXP 6480464 Curcumin results in increased activity of CASP8 protein CTD PMID:17096185 curcumin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein] and Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA] CTD PMID:23267840 and PMID:25541178 curcumin increases cleavage EXP 6480464 Curcumin results in increased cleavage of CASP8 protein CTD PMID:14555224 and PMID:22523229 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of CASP8 mRNA and Curcumin results in decreased expression of CASP8 protein CTD PMID:17148446 and PMID:33582110 curcumin multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CASP8 protein more ... CTD PMID:16173963 more ... cyanocob(III)alamin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Folic Acid inhibits the reaction [Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP8 mRNA]] and Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP8 mRNA] CTD PMID:23935743 cycloheximide multiple interactions EXP 6480464 [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein more ... CTD PMID:12760867 more ... cycloheximide increases activity EXP 6480464 Cycloheximide results in increased activity of CASP8 protein CTD PMID:15924153 cyclophosphamide multiple interactions EXP 6480464 [Methotrexate results in increased expression of CASP8 protein] which results in increased susceptibility to Cyclophosphamide metabolite more ... CTD PMID:17898787 and PMID:22010212 cyclophosphamide increases response to substance EXP 6480464 CASP8 protein results in increased susceptibility to Cyclophosphamide metabolite CTD PMID:22010212 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:15548389 cyclosporin A multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Cyclosporine inhibits the reaction [Doxorubicin results in increased activity of CASP8 protein] CTD PMID:15799720 cylindrospermopsin increases expression EXP 6480464 cylindrospermopsin results in increased expression of CASP8 mRNA CTD PMID:23726867 cytarabine multiple interactions EXP 6480464 [Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP8 protein more ... CTD PMID:12780785 more ... D-glucitol increases activity ISO Casp8 (Rattus norvegicus) 6480464 Sorbitol results in increased activity of CASP8 protein CTD PMID:20609311 D-glucitol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Testosterone inhibits the reaction [Sorbitol results in increased activity of CASP8 protein]] and Testosterone inhibits the reaction [Sorbitol results in increased activity of CASP8 protein] CTD PMID:20609311 D-gluconic acid multiple interactions EXP 6480464 [gluconic acid co-treated with Zinc Sulfate] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA] CTD PMID:27017951 D-glucose increases activity ISO Casp8 (Mus musculus) 6480464 Glucose results in increased activity of CASP8 protein CTD PMID:18973755 D-glucose multiple interactions EXP 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA and Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA] CTD PMID:33962019 D-glucose multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8] CTD PMID:18791325 D-glucose increases activity ISO Casp8 (Rattus norvegicus) 6480464 Glucose results in increased activity of CASP8 CTD PMID:18791325 dacarbazine multiple interactions EXP 6480464 Dacarbazine results in increased cleavage of and results in increased activity of CASP8 protein and TNFSF10 protein promotes the reaction [Dacarbazine results in increased cleavage of and results in increased activity of CASP8 protein] CTD PMID:17410615 daunorubicin multiple interactions EXP 6480464 [Daunorubicin co-treated with TNFSF10 protein] results in increased activity of CASP8 protein CTD PMID:12780785 DDE increases activity EXP 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of CASP8 protein CTD PMID:19545618 DDE increases activity ISO Casp8 (Rattus norvegicus) 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of CASP8 protein CTD PMID:24576310 DDE increases expression ISO Casp8 (Rattus norvegicus) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of CASP8 mRNA CTD PMID:19644561 more ... DDE decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of CASP8 protein CTD PMID:20025943 deguelin multiple interactions EXP 6480464 [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP8 protein CTD PMID:25242579 delphinidin multiple interactions EXP 6480464 [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP8 protein and delphinidin results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:25954945 and PMID:30125548 delphinidin increases expression EXP 6480464 delphinidin results in increased expression of CASP8 protein CTD PMID:33955636 demethoxycurcumin decreases expression EXP 6480464 demethoxycurcumin results in decreased expression of CASP8 mRNA CTD PMID:33582110 demethoxyfumitremorgin C increases activity EXP 6480464 demethoxyfumitremorgin C results in increased activity of CASP8 protein CTD PMID:28359723 deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of CASP8 mRNA CTD PMID:22846391 and PMID:30668976 deoxynivalenol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP8 mRNA] CTD PMID:34673182 deoxynivalenol increases expression ISO Casp8 (Rattus norvegicus) 6480464 deoxynivalenol results in increased expression of CASP8 mRNA CTD PMID:34673182 deoxynivalenol multiple interactions EXP 6480464 [Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA] more ... CTD PMID:30668976 deoxynivalenol multiple interactions ISO Casp8 (Mus musculus) 6480464 deoxynivalenol results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:22491426 desferrioxamine B increases activity EXP 6480464 Deferoxamine results in increased activity of CASP8 protein CTD PMID:16374551 desferrioxamine B multiple interactions EXP 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA more ... CTD PMID:16374551 more ... Destruxin B decreases expression EXP 6480464 destruxin B results in decreased expression of CASP8 protein CTD PMID:23751424 Destruxin B increases activity EXP 6480464 destruxin B results in increased activity of CASP8 protein CTD PMID:23751424 dexamethasone multiple interactions EXP 6480464 [afuresertib co-treated with pomalidomide co-treated with Dexamethasone] results in increased cleavage of CASP8 protein more ... CTD PMID:17070682 more ... dexamethasone increases response to substance EXP 6480464 CASP8 protein results in increased susceptibility to Dexamethasone CTD PMID:22010212 dexamethasone multiple interactions ISO Casp8 (Mus musculus) 6480464 [benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA] more ... CTD PMID:11399061 and PMID:20671745 dexamethasone multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Dexamethasone inhibits the reaction [TGFB1 protein results in increased activity of CASP8 protein] CTD PMID:15388240 dexamethasone increases activity ISO Casp8 (Mus musculus) 6480464 Dexamethasone results in increased activity of CASP8 protein CTD PMID:11399061 dexamethasone increases activity EXP 6480464 Dexamethasone results in increased activity of CASP8 protein CTD PMID:15576458 dexmedetomidine increases activity EXP 6480464 Dexmedetomidine results in increased activity of CASP8 protein CTD PMID:18724006 dextran sulfate decreases expression ISO Casp8 (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of CASP8 protein CTD PMID:29496522 dextran sulfate multiple interactions ISO Casp8 (Mus musculus) 6480464 dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in decreased expression of CASP8 protein] CTD PMID:29496522 Di-n-hexyl phthalate increases expression EXP 6480464 di-n-hexyl phthalate results in increased expression of CASP8 mRNA CTD PMID:33043605 Di-n-octyl phthalate decreases expression ISO Casp8 (Mus musculus) 6480464 di-n-octyl phthalate results in decreased expression of CASP8 protein CTD PMID:29128616 Di-n-octyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of CASP8 protein CTD PMID:35739755 and PMID:37364641 diallyl disulfide increases cleavage EXP 6480464 diallyl disulfide results in increased cleavage of CASP8 protein CTD PMID:30677442 diallyl disulfide multiple interactions EXP 6480464 diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP8 protein] CTD PMID:30677442 diallyl trisulfide multiple interactions EXP 6480464 [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein and Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein] CTD PMID:22578287 and PMID:28571773 diallyl trisulfide increases activity EXP 6480464 diallyl trisulfide results in increased activity of CASP8 protein CTD PMID:22595511 diallyl trisulfide increases cleavage EXP 6480464 diallyl trisulfide results in increased cleavage of CASP8 protein CTD PMID:22578287 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CASP8 mRNA more ... CTD PMID:20953137 more ... diarsenic trioxide increases activity ISO Casp8 (Mus musculus) 6480464 Arsenic Trioxide results in increased activity of CASP8 protein CTD PMID:21565247 and PMID:25410152 diarsenic trioxide increases activity EXP 6480464 Arsenic Trioxide results in increased activity of CASP8 protein CTD PMID:10721769 more ... diarsenic trioxide multiple interactions ISO Casp8 (Mus musculus) 6480464 Arsenic Trioxide promotes the reaction [Drugs and Chinese Herbal results in increased cleavage of CASP8 protein] CTD PMID:28587418 diarsenic trioxide multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of CASP8 mRNA more ... CTD PMID:16174796 more ... diarsenic trioxide increases cleavage EXP 6480464 Arsenic Trioxide results in increased cleavage of CASP8 protein CTD PMID:18491231 more ... diarsenic trioxide affects activity EXP 6480464 Arsenic Trioxide affects the activity of CASP8 protein CTD PMID:16010437 diazinon affects expression ISO Casp8 (Rattus norvegicus) 6480464 Diazinon affects the expression of CASP8 mRNA CTD PMID:22546817 diazinon multiple interactions EXP 6480464 Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP8 mRNA] and Selenium analog inhibits the reaction [Diazinon results in increased expression of CASP8 mRNA] CTD PMID:27920530 diazinon increases expression EXP 6480464 Diazinon results in increased expression of CASP8 mRNA CTD PMID:27920530 dibenziodolium multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [diphenyleneiodonium co-treated with mitoquinol co-treated with mitoquinone] inhibits the reaction [Doxorubicin results in increased activity of CASP8 protein] CTD PMID:15799720 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [Patulin results in increased activity of CASP8 protein] CTD PMID:33577942 dibenziodolium increases activity EXP 6480464 diphenyleneiodonium results in increased activity of CASP8 protein CTD PMID:33577942 dibutyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein more ... CTD PMID:28013214 more ... dibutyl phthalate increases expression ISO Casp8 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of CASP8 protein CTD PMID:31712109 dichloroacetic acid increases expression ISO Casp8 (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of CASP8 mRNA CTD PMID:28962523 diclofenac increases activity ISO Casp8 (Rattus norvegicus) 6480464 Diclofenac results in increased activity of CASP8 protein CTD PMID:14609740 diclofenac affects expression EXP 6480464 Diclofenac affects the expression of CASP8 mRNA CTD PMID:24752500 diclofenac increases activity EXP 6480464 Diclofenac results in increased activity of CASP8 protein CTD PMID:27313093 diclofenac multiple interactions EXP 6480464 [Diclofenac co-treated with Hyaluronic Acid] results in increased activity of CASP8 protein more ... CTD PMID:20237495 and PMID:27313093 dieckol increases activity EXP 6480464 dieckol results in increased activity of CASP8 protein CTD PMID:31291034 dieldrin affects expression ISO Casp8 (Rattus norvegicus) 6480464 Dieldrin affects the expression of CASP8 mRNA CTD PMID:22546817 diepoxybutane increases expression EXP 6480464 diepoxybutane results in increased expression of CASP8 mRNA CTD PMID:29792945 diethyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein more ... CTD PMID:28013214 more ... diethyldithiocarbamic acid multiple interactions EXP 6480464 [Ditiocarb binds to Copper] which results in increased activity of CASP8 protein CTD PMID:22951949 diethylstilbestrol increases expression ISO Casp8 (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of CASP8 mRNA CTD PMID:15545218 diethylstilbestrol increases expression ISO Casp8 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of CASP8 mRNA CTD PMID:21658437 digitoxin increases cleavage EXP 6480464 Digitoxin analog results in increased cleavage of CASP8 protein and Digitoxin results in increased cleavage of CASP8 protein CTD PMID:22037315 and PMID:34717917 digitoxin multiple interactions EXP 6480464 Digitoxin affects the reaction [HIF1A protein affects the cleavage of CASP8 protein] more ... CTD PMID:34717917 Dihydrotanshinone I multiple interactions ISO Casp8 (Mus musculus) 6480464 dihydrotanshinone I inhibits the reaction [[Lipopolysaccharides co-treated with benzyloxycarbonyl-valyl-alanyl-aspartic acid] results in decreased expression of CASP8 protein] and dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in decreased expression of CASP8 protein] CTD PMID:29496522 diisobutyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CASP8 mRNA CTD PMID:28013214 Diisodecyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of CASP8 protein CTD PMID:35739755 and PMID:37364641 diisononyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein more ... CTD PMID:28013214 more ... Dimethyl phthalate increases expression ISO Casp8 (Rattus norvegicus) 6480464 dimethyl phthalate results in increased expression of CASP8 mRNA CTD PMID:35598668 dimethylarsinic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [CASP8 protein results in increased susceptibility to Cacodylic Acid] CTD PMID:15276415 dimethylarsinic acid increases response to substance ISO Casp8 (Rattus norvegicus) 6480464 CASP8 protein results in increased susceptibility to Cacodylic Acid CTD PMID:15276415 dioscin increases activity EXP 6480464 dioscin results in increased activity of CASP8 protein CTD PMID:22334414 dioscin decreases expression EXP 6480464 dioscin results in decreased expression of CASP8 mRNA CTD PMID:33359023 dioscin multiple interactions EXP 6480464 dioscin results in decreased expression of and results in increased cleavage of CASP8 protein CTD PMID:33359023 dioscin increases expression EXP 6480464 dioscin results in increased expression of CASP8 mRNA and dioscin results in increased expression of CASP8 protein CTD PMID:29990575 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of CASP8 mRNA CTD PMID:23452621 dioxygen multiple interactions EXP 6480464 3 more ... CTD PMID:23452621 dipyridamole multiple interactions EXP 6480464 Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP8 protein] CTD PMID:17303086 diquat multiple interactions ISO Casp8 (Mus musculus) 6480464 [Antioxidants results in decreased susceptibility to Diquat] which results in decreased expression of CASP8 mRNA CTD PMID:32536062 disodium selenite increases expression ISO Casp8 (Mus musculus) 6480464 Sodium Selenite results in increased expression of CASP8 mRNA CTD PMID:19363675 disodium selenite increases cleavage EXP 6480464 Sodium Selenite results in increased cleavage of CASP8 protein CTD PMID:34520753 disodium selenite decreases activity ISO Casp8 (Rattus norvegicus) 6480464 Sodium Selenite results in decreased activity of CASP8 protein CTD PMID:18209489 docebenone multiple interactions ISO Casp8 (Mus musculus) 6480464 2 more ... CTD PMID:25432964 donepezil hydrochloride increases activity EXP 6480464 Donepezil results in increased activity of CASP8 protein CTD PMID:20522977 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP8 protein] more ... CTD PMID:15812552 more ... doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of CASP8 mRNA CTD PMID:30581319 doxorubicin increases expression ISO Casp8 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of CASP8 protein CTD PMID:27087047 doxorubicin increases response to substance EXP 6480464 CASP8 protein results in increased susceptibility to Doxorubicin CTD PMID:22010212 doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of CASP8 protein CTD PMID:15868924 more ... doxorubicin increases expression ISO Casp8 (Mus musculus) 6480464 Doxorubicin results in increased expression of CASP8 mRNA and Doxorubicin results in increased expression of CASP8 protein CTD PMID:26873546 and PMID:32289291 doxorubicin increases activity ISO Casp8 (Rattus norvegicus) 6480464 Doxorubicin results in increased activity of CASP8 protein CTD PMID:15799720 more ... doxorubicin increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Doxorubicin results in increased cleavage of CASP8 protein CTD PMID:12107157 more ... doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CASP8 mRNA and Doxorubicin results in increased expression of CASP8 protein CTD PMID:16001973 and PMID:25339540 doxorubicin increases cleavage EXP 6480464 Doxorubicin analog results in increased cleavage of CASP8 protein and Doxorubicin results in increased cleavage of CASP8 protein CTD PMID:15981920 more ... doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of CASP8 mRNA CTD PMID:16705698 doxorubicin affects activity EXP 6480464 Doxorubicin affects the activity of CASP8 protein CTD PMID:15870702 doxorubicin multiple interactions ISO Casp8 (Mus musculus) 6480464 [zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP8 protein CTD PMID:19789217 doxorubicin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 1 more ... CTD PMID:15799720 more ... doxorubicin increases activity ISO Casp8 (Mus musculus) 6480464 Doxorubicin results in increased activity of CASP8 protein CTD PMID:16018998 Echimidine multiple interactions EXP 6480464 echimidine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 Echinocystic acid increases activity EXP 6480464 echinocystic acid analog results in increased activity of CASP8 protein CTD PMID:15863893 eckol multiple interactions EXP 6480464 [eckol co-treated with temozolomide] results in increased cleavage of CASP8 protein CTD PMID:21514314 edaravone decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Edaravone results in decreased expression of CASP8 protein CTD PMID:17967739 elemental carbon multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA CTD PMID:31268311 elemental selenium multiple interactions EXP 6480464 [Doxorubicin co-treated with Selenium] promotes the reaction [FADD protein binds to CASP8 protein] more ... CTD PMID:17970047 and PMID:27920530 elemental selenium increases activity EXP 6480464 Selenium results in increased activity of CASP8 protein CTD PMID:12432279 elemental selenium decreases expression EXP 6480464 Selenium results in decreased expression of CASP8 mRNA CTD PMID:19244175 ellipticine multiple interactions EXP 6480464 ellipticine results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:21843585 emodin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased activity of CASP8 protein] more ... CTD PMID:27032576 emodin increases activity EXP 6480464 Emodin results in increased activity of CASP8 protein CTD PMID:27032576 endosulfan multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Endosulfan results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:30796443 entinostat increases expression EXP 6480464 entinostat results in increased expression of CASP8 mRNA CTD PMID:26272509 entinostat multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CASP8 mRNA CTD PMID:27188386 enzalutamide decreases expression EXP 6480464 enzalutamide results in decreased expression of CASP8 protein CTD PMID:32805266 epichlorohydrin increases expression EXP 6480464 Epichlorohydrin results in increased expression of CASP8 mRNA CTD PMID:29792945 epoxiconazole decreases expression ISO Casp8 (Mus musculus) 6480464 epoxiconazole results in decreased expression of CASP8 mRNA CTD PMID:35436446 esculetin multiple interactions EXP 6480464 [esculetin co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:16051289 etacrynic acid multiple interactions EXP 6480464 [arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of CASP8 protein CTD PMID:23082001 etacrynic acid increases cleavage EXP 6480464 Ethacrynic Acid results in increased cleavage of CASP8 protein CTD PMID:23082001 ethanol increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Ethanol results in increased cleavage of CASP8 protein CTD PMID:25859307 and PMID:29085585 ethanol multiple interactions ISO Casp8 (Mus musculus) 6480464 sodium propionate inhibits the reaction [Ethanol results in increased expression of CASP8 mRNA] CTD PMID:35639301 ethanol increases expression ISO Casp8 (Rattus norvegicus) 6480464 Ethanol results in increased expression of CASP8 mRNA CTD PMID:36085217 ethanol increases activity ISO Casp8 (Rattus norvegicus) 6480464 Ethanol results in increased activity of CASP8 protein CTD PMID:25289771 ethanol increases expression ISO Casp8 (Mus musculus) 6480464 Ethanol results in increased expression of CASP8 mRNA and Ethanol results in increased expression of CASP8 protein CTD PMID:19429258 and PMID:35639301 ethanol multiple interactions EXP 6480464 ALDH2 protein inhibits the reaction [Ethanol results in increased expression of CASP8 protein] CTD PMID:19429258 ethanol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [2 more ... CTD PMID:25289771 more ... ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 [1 more ... CTD PMID:29111403 etoposide multiple interactions EXP 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:15475000 more ... etoposide increases response to substance EXP 6480464 CASP8 protein results in increased susceptibility to Etoposide CTD PMID:22010212 etoposide increases cleavage EXP 6480464 Etoposide results in increased cleavage of CASP8 protein CTD PMID:21801448 etoposide increases activity EXP 6480464 Etoposide results in increased activity of CASP8 protein CTD PMID:15475000 etoposide decreases response to substance EXP 6480464 CASP8 protein mutant form results in decreased susceptibility to Etoposide CTD PMID:21801448 fangchinoline increases cleavage EXP 6480464 fangchinoline results in increased cleavage of CASP8 protein CTD PMID:28754437 fenbendazole increases expression EXP 6480464 Fenbendazole analog results in increased expression of CASP8 mRNA and Fenbendazole results in increased expression of CASP8 mRNA CTD PMID:35569513 fingolimod hydrochloride increases cleavage EXP 6480464 Fingolimod Hydrochloride results in increased cleavage of CASP8 protein CTD PMID:25939952 fingolimod hydrochloride multiple interactions EXP 6480464 SQSTM1 mutant form inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of CASP8 protein] CTD PMID:25939952 fisetin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [fisetin results in increased activity of CASP8 protein] more ... CTD PMID:21216935 and PMID:21964635 fisetin increases activity EXP 6480464 fisetin results in increased activity of CASP8 protein CTD PMID:21964635 and PMID:28181380 flavanone multiple interactions EXP 6480464 [benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] which results in decreased susceptibility to flavanone and flavanone results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:22056764 flavones increases activity EXP 6480464 Flavones analog results in increased activity of CASP8 protein CTD PMID:20674374 flavonols multiple interactions EXP 6480464 Flavonols results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:28235426 fluoxetine increases activity ISO Casp8 (Mus musculus) 6480464 Fluoxetine results in increased activity of CASP8 protein CTD PMID:28482088 fluticasone multiple interactions EXP 6480464 [Fluticasone co-treated with Salmeterol Xinafoate] results in increased activity of CASP8 protein CTD PMID:15536434 fluvastatin increases activity EXP 6480464 fluvastatin results in increased activity of CASP8 protein CTD PMID:24964743 fluvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [fluvastatin results in increased activity of CASP8 protein] CTD PMID:24964743 folic acid affects expression EXP 6480464 Folic Acid affects the expression of CASP8 mRNA CTD PMID:16361273 folic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Folic Acid inhibits the reaction [Dietary Fats results in increased expression of CASP8 mRNA] and Folic Acid inhibits the reaction [Vitamin B 12 promotes the reaction [Dietary Fats results in increased expression of CASP8 mRNA]] CTD PMID:23935743 folic acid multiple interactions EXP 6480464 Folic Acid affects the reaction [Homocysteine affects the expression of CASP8 mRNA] more ... CTD PMID:29250709 and PMID:30581319 folic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 [1 more ... CTD PMID:20938992 and PMID:22206623 formaldehyde increases expression ISO Casp8 (Rattus norvegicus) 6480464 Formaldehyde results in increased expression of CASP8 mRNA CTD PMID:20448356 formaldehyde increases activity ISO Casp8 (Rattus norvegicus) 6480464 Formaldehyde results in increased activity of CASP8 protein CTD PMID:20448356 formononetin increases activity EXP 6480464 formononetin results in increased activity of CASP8 protein CTD PMID:23867903 formononetin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP8 mRNA] more ... CTD PMID:23867903 formononetin increases expression EXP 6480464 formononetin results in increased expression of CASP8 mRNA CTD PMID:23867903 fructose multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Plant Extracts inhibits the reaction [Fructose results in decreased cleavage of CASP8 protein] CTD PMID:33475235 fructose decreases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Fructose results in decreased cleavage of CASP8 protein CTD PMID:33475235 furan increases expression ISO Casp8 (Rattus norvegicus) 6480464 furan results in increased expression of CASP8 mRNA CTD PMID:27387713 furosemide affects expression ISO Casp8 (Rattus norvegicus) 6480464 Furosemide affects the expression of CASP8 mRNA CTD PMID:17497460 Fusarenone X increases expression ISO Casp8 (Mus musculus) 6480464 fusarenon-X results in increased expression of CASP8 mRNA CTD PMID:24983900 gallic acid increases expression EXP 6480464 Gallic Acid results in increased expression of CASP8 protein CTD PMID:22245431 gallium atom increases activity EXP 6480464 Gallium results in increased activity of CASP8 protein CTD PMID:21194614 gardenin B multiple interactions EXP 6480464 gardenin B results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:27423764 gedunin increases activity EXP 6480464 gedunin results in increased activity of CASP8 protein CTD PMID:21381696 gefitinib increases cleavage EXP 6480464 Gefitinib results in increased cleavage of CASP8 protein CTD PMID:31168030 gemcitabine increases activity EXP 6480464 Gemcitabine results in increased activity of CASP8 protein CTD PMID:12479703 and PMID:17159604 gemcitabine multiple interactions EXP 6480464 [Calcitriol co-treated with Gemcitabine] results in increased expression of CASP8 protein more ... CTD PMID:17671697 more ... gemcitabine increases cleavage EXP 6480464 Gemcitabine results in increased cleavage of CASP8 protein CTD PMID:14750167 genistein multiple interactions EXP 6480464 [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP8 protein more ... CTD PMID:18546268 more ... gentamycin increases activity ISO Casp8 (Rattus norvegicus) 6480464 Gentamicins results in increased activity of CASP8 protein CTD PMID:17132701 gentamycin increases expression ISO Casp8 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of CASP8 mRNA CTD PMID:33387578 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CASP8 mRNA CTD PMID:29992668 gentamycin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 tetramethylpyrazine inhibits the reaction [Gentamicins results in increased activity of CASP8 protein] more ... CTD PMID:17132701 Gentiopicrin multiple interactions ISO Casp8 (Mus musculus) 6480464 gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP8 protein] and gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP8 protein modified form] CTD PMID:20558151 geraniol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein] and geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA] CTD PMID:21907755 geraniol increases expression EXP 6480464 geraniol results in increased expression of CASP8 mRNA and geraniol results in increased expression of CASP8 protein CTD PMID:30506710 gibberellin A3 decreases methylation ISO Casp8 (Rattus norvegicus) 6480464 gibberellic acid results in decreased methylation of CASP8 gene and gibberellic acid results in decreased methylation of CASP8 promoter CTD PMID:31733319 gibberellin A3 increases expression ISO Casp8 (Rattus norvegicus) 6480464 gibberellic acid results in increased expression of CASP8 mRNA and gibberellic acid results in increased expression of CASP8 protein CTD PMID:31733319 gingerol multiple interactions EXP 6480464 [TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein and Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein] CTD PMID:25034532 gingerol increases cleavage EXP 6480464 gingerol results in increased cleavage of CASP8 protein CTD PMID:28249781 gingerol affects activity ISO Casp8 (Mus musculus) 6480464 gingerol affects the activity of CASP8 protein CTD PMID:17454143 glabridin increases cleavage EXP 6480464 glabridin results in increased cleavage of CASP8 protein CTD PMID:29663662 glucose increases activity ISO Casp8 (Mus musculus) 6480464 Glucose results in increased activity of CASP8 protein CTD PMID:18973755 glucose multiple interactions EXP 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA and Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA] CTD PMID:33962019 glucose multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8] CTD PMID:18791325 glucose increases activity ISO Casp8 (Rattus norvegicus) 6480464 Glucose results in increased activity of CASP8 CTD PMID:18791325 glutaraldehyde decreases expression EXP 6480464 Glutaral results in decreased expression of CASP8 mRNA CTD PMID:28236482 glutathione multiple interactions ISO Casp8 (Mus musculus) 6480464 Glutathione inhibits the reaction [Acrolein results in increased expression of CASP8 protein] CTD PMID:24376112 glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [1 more ... CTD PMID:24515801 glycochenodeoxycholic acid increases activity ISO Casp8 (Rattus norvegicus) 6480464 Glycochenodeoxycholic Acid results in increased activity of CASP8 protein CTD PMID:12873810 and PMID:15767249 glycochenodeoxycholic acid increases cleavage ISO Casp8 (Mus musculus) 6480464 Glycochenodeoxycholic Acid results in increased cleavage of CASP8 protein CTD PMID:25125499 glycyrrhizinic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP8 protein] CTD PMID:22051199 glycyrrhizinic acid increases activity EXP 6480464 Glycyrrhizic Acid results in increased activity of CASP8 protein CTD PMID:35844403 glyphosate multiple interactions EXP 6480464 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 mRNA and [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 protein CTD PMID:32800223 gold atom increases expression EXP 6480464 Gold results in increased expression of CASP8 mRNA CTD PMID:22178767 gold atom decreases expression EXP 6480464 Gold analog results in decreased expression of CASP8 mRNA CTD PMID:36057382 gold(0) increases expression EXP 6480464 Gold results in increased expression of CASP8 mRNA CTD PMID:22178767 gold(0) decreases expression EXP 6480464 Gold analog results in decreased expression of CASP8 mRNA CTD PMID:36057382 Grifolin increases activity EXP 6480464 grifolin results in increased activity of CASP8 protein CTD PMID:15949805 guggulsterone increases activity EXP 6480464 pregna-4 more ... CTD PMID:17475222 helenalin multiple interactions EXP 6480464 helenalin inhibits the reaction [CD 437 results in increased activity of CASP8 protein] CTD PMID:16024638 Heliotrine increases cleavage EXP 6480464 heliotrine results in increased cleavage of CASP8 protein CTD PMID:29458164 hexachlorobenzene increases activity ISO Casp8 (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased activity of CASP8 protein CTD PMID:21787832 and PMID:23708402 homocysteine multiple interactions EXP 6480464 Folic Acid affects the reaction [Homocysteine affects the expression of CASP8 mRNA] and Folic Acid affects the reaction [Homocysteine affects the expression of CASP8 protein] CTD PMID:29250709 homocysteine affects expression EXP 6480464 Homocysteine affects the expression of CASP8 mRNA and Homocysteine affects the expression of CASP8 protein CTD PMID:29250709 Honokiol increases activity EXP 6480464 honokiol results in increased activity of CASP8 protein CTD PMID:15802533 hyaluronic acid multiple interactions EXP 6480464 [Diclofenac co-treated with Hyaluronic Acid] results in increased activity of CASP8 protein CTD PMID:20237495 hydrogen peroxide increases activity ISO Casp8 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased activity of CASP8 protein CTD PMID:15799720 more ... hydrogen peroxide increases expression ISO Casp8 (Mus musculus) 6480464 Hydrogen Peroxide results in increased expression of CASP8 mRNA CTD PMID:31696622 hydrogen peroxide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 1 more ... CTD PMID:15799720 more ... hydrogen peroxide increases expression ISO Casp8 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased expression of CASP8 protein CTD PMID:20946910 and PMID:27525270 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of CASP8 protein CTD PMID:21179406 hydrogen peroxide multiple interactions EXP 6480464 Melatonin promotes the reaction [Hydrogen Peroxide results in increased activity of CASP8 protein] CTD PMID:21431366 hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of CASP8 protein CTD PMID:21431366 hydroquinone multiple interactions EXP 6480464 FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein] more ... CTD PMID:15777082 and PMID:23288922 hydroquinone increases cleavage EXP 6480464 hydroquinone results in increased cleavage of CASP8 protein CTD PMID:23288922 hydroquinone increases expression ISO Casp8 (Mus musculus) 6480464 hydroquinone results in increased expression of CASP8 protein CTD PMID:27606422 hydroquinone increases activity EXP 6480464 hydroquinone results in increased activity of CASP8 protein CTD PMID:23776099 hydroquinone O-beta-D-glucopyranoside decreases expression EXP 6480464 Arbutin results in decreased expression of CASP8 mRNA CTD PMID:17103032 hydroxyurea increases expression ISO Casp8 (Mus musculus) 6480464 Hydroxyurea results in increased expression of CASP8 protein CTD PMID:26399158 hyperforin increases cleavage EXP 6480464 hyperforin results in increased cleavage of CASP8 protein CTD PMID:32485087 icariside II increases activity EXP 6480464 baohuoside I results in increased activity of CASP8 protein CTD PMID:19289254 idelalisib multiple interactions EXP 6480464 [TNF protein co-treated with idelalisib] results in increased activity of CASP8 protein more ... CTD PMID:31445927 Ilimaquinone increases cleavage EXP 6480464 ilimaquinone results in increased cleavage of CASP8 protein CTD PMID:24930757 imipramine multiple interactions ISO Casp8 (Mus musculus) 6480464 Imipramine inhibits the reaction [lead acetate results in increased activity of CASP8 protein] CTD PMID:22033380 indirubin-3'-monoxime multiple interactions EXP 6480464 [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CASP8 mRNA CTD PMID:18958680 indometacin multiple interactions EXP 6480464 [Indomethacin results in increased activity of CASP8 protein] which results in increased susceptibility to Doxorubicin more ... CTD PMID:15265368 and PMID:15812552 indometacin decreases activity ISO Casp8 (Rattus norvegicus) 6480464 Indomethacin results in decreased activity of CASP8 protein CTD PMID:19615346 ionomycin multiple interactions EXP 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] more ... CTD PMID:12165276 and PMID:15477007 irinotecan increases activity EXP 6480464 Irinotecan results in increased activity of CASP8 protein CTD PMID:16432164 irinotecan multiple interactions EXP 6480464 Irinotecan promotes the reaction [AS602868 results in increased cleavage of and results in increased activity of CASP8 protein] more ... CTD PMID:16432164 and PMID:18182997 iron dichloride increases expression EXP 6480464 ferrous chloride results in increased expression of CASP8 mRNA CTD PMID:35984750 iron(III) nitrilotriacetate multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein more ... CTD PMID:21907755 isoflavones increases expression ISO Casp8 (Rattus norvegicus) 6480464 Isoflavones results in increased expression of CASP8 mRNA CTD PMID:25035168 isoflurane multiple interactions ISO Casp8 (Mus musculus) 6480464 resveratrol inhibits the reaction [Isoflurane results in increased activity of CASP8 protein] CTD PMID:23922164 isoflurane increases activity ISO Casp8 (Mus musculus) 6480464 Isoflurane results in increased activity of CASP8 protein CTD PMID:23922164 isoliquiritigenin increases activity EXP 6480464 isoliquiritigenin results in increased activity of CASP8 protein CTD PMID:16158945 isoprenaline increases expression ISO Casp8 (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of CASP8 mRNA and Isoproterenol results in increased expression of CASP8 protein CTD PMID:25794854 more ... isoprenaline multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP8 protein] more ... CTD PMID:25794854 more ... isotretinoin increases cleavage EXP 6480464 Isotretinoin results in increased cleavage of CASP8 protein CTD PMID:16135400 isotretinoin increases expression ISO Casp8 (Mus musculus) 6480464 Isotretinoin results in increased expression of CASP8 protein CTD PMID:27606422 ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of CASP8 protein CTD PMID:32959892 juglone increases activity EXP 6480464 juglone results in increased activity of CASP8 protein CTD PMID:20138029 kojic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA CTD PMID:18544905 L-1,4-dithiothreitol multiple interactions ISO Casp8 (Mus musculus) 6480464 Dithiothreitol inhibits the reaction [2-methyl-3-(2-((4-nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester results in decreased activity of CASP8 protein] CTD PMID:11226294 L-ascorbic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with INS1 protein] results in increased expression of CASP8 mRNA and [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA CTD PMID:18544905 and PMID:20400526 L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of CASP8 mRNA CTD PMID:30597948 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein] CTD PMID:23711929 L-methionine multiple interactions ISO Casp8 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CASP8 gene CTD PMID:20938992 lactacystin multiple interactions ISO Casp8 (Mus musculus) 6480464 lactacystin inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]] CTD PMID:20671745 lead diacetate multiple interactions ISO Casp8 (Mus musculus) 6480464 1 more ... CTD PMID:22033380 lead diacetate increases activity ISO Casp8 (Mus musculus) 6480464 lead acetate results in increased activity of CASP8 protein CTD PMID:22033380 Licochalcone A multiple interactions EXP 6480464 SB 203580 inhibits the reaction [licochalcone A results in increased cleavage of CASP8 protein] CTD PMID:30983163 Licochalcone A increases expression EXP 6480464 licochalcone A results in increased expression of CASP8 mRNA CTD PMID:30055311 Licochalcone A increases cleavage EXP 6480464 licochalcone A results in increased cleavage of CASP8 protein CTD PMID:30983163 Licochalcone B increases cleavage EXP 6480464 licochalcone B results in increased cleavage of CASP8 protein CTD PMID:35948134 Licochalcone B multiple interactions EXP 6480464 TNFRSF10B protein promotes the reaction [licochalcone B results in increased cleavage of CASP8 protein] CTD PMID:35948134 linalool increases expression EXP 6480464 linalool results in increased expression of CASP8 mRNA CTD PMID:26703569 lipoic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in decreased expression of CASP8 mRNA CTD PMID:23830814 lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Zinc Oxide analog results in increased activity of CASP8 protein] CTD PMID:27544635 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of CASP8 protein CTD PMID:21844306 lipopolysaccharide decreases expression ISO Casp8 (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of CASP8 mRNA and Lipopolysaccharides results in decreased expression of CASP8 protein CTD PMID:35833596 lipopolysaccharide increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased cleavage of CASP8 protein CTD PMID:31486215 lipopolysaccharide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Honghua extract more ... CTD PMID:31486215 lipopolysaccharide increases cleavage ISO Casp8 (Mus musculus) 6480464 Lipopolysaccharides results in increased cleavage of CASP8 protein CTD PMID:30776389 lipopolysaccharide increases activity ISO Casp8 (Mus musculus) 6480464 Lipopolysaccharides results in increased activity of CASP8 protein CTD PMID:23170834 lipopolysaccharide increases expression ISO Casp8 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of CASP8 mRNA CTD PMID:23107598 lipopolysaccharide multiple interactions ISO Casp8 (Mus musculus) 6480464 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP8 protein] more ... CTD PMID:20558151 more ... Lipstatin multiple interactions EXP 6480464 lipstatin analog results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:20577697 lithium atom multiple interactions EXP 6480464 Lithium inhibits the reaction [Camptothecin results in increased activity of CASP8 protein] and Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein] CTD PMID:15475000 lithium hydride multiple interactions EXP 6480464 Lithium inhibits the reaction [Camptothecin results in increased activity of CASP8 protein] and Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein] CTD PMID:15475000 lithocholic acid multiple interactions EXP 6480464 [[[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein] which results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein more ... CTD PMID:19054763 lonafarnib multiple interactions EXP 6480464 [lonafarnib co-treated with Bortezomib] results in increased cleavage of CASP8 protein CTD PMID:16118318 lonidamine multiple interactions EXP 6480464 [arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein and BCL2 protein inhibits the reaction [[arsenic trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of CASP8 protein] CTD PMID:21889928 loratadine increases cleavage EXP 6480464 Loratadine results in increased cleavage of CASP8 protein CTD PMID:20570632 losartan decreases activity ISO Casp8 (Rattus norvegicus) 6480464 Losartan results in decreased activity of CASP8 protein CTD PMID:23875703 lovastatin increases activity EXP 6480464 Lovastatin results in increased activity of CASP8 protein CTD PMID:15705602 lovastatin increases activity ISO Casp8 (Mus musculus) 6480464 Lovastatin results in increased activity of CASP8 protein CTD PMID:15180944 lupeol increases expression EXP 6480464 lupeol results in increased expression of CASP8 mRNA and lupeol results in increased expression of CASP8 protein CTD PMID:30506710 Lupiwighteone increases cleavage EXP 6480464 lupiwighteone results in increased cleavage of CASP8 protein CTD PMID:31604113 luteolin multiple interactions EXP 6480464 [Luteolin co-treated with Paclitaxel] results in increased cleavage of CASP8 protein more ... CTD PMID:15334063 more ... luteolin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Luteolin inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP8 protein] CTD PMID:27525270 Luteolin 7-methyl ether multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Apigenin promotes the reaction [hydroxygenkwanin results in increased activity of CASP8 protein] and hydroxygenkwanin promotes the reaction [Apigenin results in increased activity of CASP8 protein] CTD PMID:24144774 Luteolin 7-methyl ether increases activity ISO Casp8 (Rattus norvegicus) 6480464 hydroxygenkwanin results in increased activity of CASP8 protein CTD PMID:24144774 luteolin 7-O-beta-D-glucoside increases cleavage EXP 6480464 luteolin-7-glucoside results in increased cleavage of CASP8 protein CTD PMID:34165247 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP8 protein] more ... CTD PMID:15850772 more ... LY294002 increases activity EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased activity of CASP8 protein CTD PMID:15942663 lycopene multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] and lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] CTD PMID:16030430 lycopene decreases expression EXP 6480464 lycopene results in decreased expression of CASP8 mRNA CTD PMID:16886892 Maduramicin increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 maduramicin results in increased cleavage of CASP8 protein CTD PMID:29047155 magnesium oxide multiple interactions EXP 6480464 Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP8 mRNA] CTD PMID:27920530 malathion increases activity ISO Casp8 (Mus musculus) 6480464 Malathion results in increased activity of CASP8 protein CTD PMID:12505448 mancozeb increases activity EXP 6480464 mancozeb results in increased activity of CASP8 protein CTD PMID:22824503 maneb increases activity EXP 6480464 Maneb results in increased activity of CASP8 protein CTD PMID:22824503 manganese atom increases activity ISO Casp8 (Rattus norvegicus) 6480464 Manganese results in increased activity of CASP8 protein CTD PMID:31161640 manganese atom multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Rolipram inhibits the reaction [Manganese results in increased activity of CASP8 protein] CTD PMID:31161640 manganese(0) multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Rolipram inhibits the reaction [Manganese results in increased activity of CASP8 protein] CTD PMID:31161640 manganese(0) increases activity ISO Casp8 (Rattus norvegicus) 6480464 Manganese results in increased activity of CASP8 protein CTD PMID:31161640 manganese(II) chloride increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 manganese chloride results in increased cleavage of CASP8 protein CTD PMID:21704098 and PMID:28378122 manganese(II) chloride multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein] more ... CTD PMID:28378122 mangiferin increases expression EXP 6480464 mangiferin results in increased expression of CASP8 protein CTD PMID:32420661 mangiferin multiple interactions EXP 6480464 mangiferin inhibits the reaction [aluminum maltolate results in increased activity of CASP8 protein] CTD PMID:37455591 masoprocol multiple interactions EXP 6480464 [Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:17645780 masoprocol multiple interactions ISO Casp8 (Mus musculus) 6480464 Masoprocol inhibits the reaction [FASL protein results in increased activity of CASP8 protein] CTD PMID:10203695 masoprocol increases expression EXP 6480464 Masoprocol results in increased expression of CASP8 protein CTD PMID:17645780 MeIQx decreases expression EXP 6480464 2-amino-3 more ... CTD PMID:20816883 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA] and Melatonin promotes the reaction [Hydrogen Peroxide results in increased activity of CASP8 protein] CTD PMID:21431366 and PMID:33962019 melatonin multiple interactions ISO Casp8 (Mus musculus) 6480464 Melatonin inhibits the reaction [Atrazine results in increased cleavage of CASP8 protein] and Melatonin inhibits the reaction [Cadmium Chloride results in decreased expression of CASP8 protein] CTD PMID:25259610 and PMID:35844137 melatonin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [bisphenol A results in increased activity of CASP8 protein] CTD PMID:25454643 melatonin increases activity EXP 6480464 Melatonin results in increased activity of CASP8 protein CTD PMID:19012662 melittin increases expression EXP 6480464 Melitten results in increased expression of CASP8 protein modified form CTD PMID:22027265 mercury dibromide increases expression EXP 6480464 mercuric bromide results in increased expression of CASP8 mRNA CTD PMID:26272509 mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CASP8 mRNA CTD PMID:27188386 mercury dichloride multiple interactions ISO Casp8 (Mus musculus) 6480464 [Mercuric Chloride co-treated with sodium arsenite co-treated with Cadmium Chloride] results in increased activity of CASP8 protein CTD PMID:16421179 mercury dichloride increases activity ISO Casp8 (Mus musculus) 6480464 Mercuric Chloride results in increased activity of CASP8 protein CTD PMID:16421179 metformin decreases activity EXP 6480464 Metformin results in decreased activity of CASP8 protein CTD PMID:15531508 metformin multiple interactions EXP 6480464 [Paclitaxel co-treated with Metformin] results in increased expression of CASP8 mRNA CTD PMID:29309887 methotrexate multiple interactions EXP 6480464 [Methotrexate results in increased expression of CASP8 protein] which results in increased susceptibility to Antineoplastic Agents more ... CTD PMID:17637740 more ... methotrexate increases expression ISO Casp8 (Rattus norvegicus) 6480464 Methotrexate results in increased expression of CASP8 protein CTD PMID:36482745 methotrexate multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 ramelteon inhibits the reaction [Methotrexate results in increased expression of CASP8 protein] CTD PMID:36482745 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of CASP8 mRNA and Methotrexate results in increased expression of CASP8 protein CTD PMID:17400583 more ... methoxsalen decreases expression EXP 6480464 Methoxsalen results in decreased expression of CASP8 protein CTD PMID:22796345 methoxychlor increases activity ISO Casp8 (Mus musculus) 6480464 Methoxychlor results in increased activity of CASP8 protein CTD PMID:20568958 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of CASP8 mRNA CTD PMID:28001369 Methylone increases activity ISO Casp8 (Rattus norvegicus) 6480464 methylone results in increased activity of CASP8 protein CTD PMID:27255387 methylphenidate increases expression ISO Casp8 (Rattus norvegicus) 6480464 Methylphenidate results in increased expression of CASP8 mRNA CTD PMID:32746681 methylseleninic acid multiple interactions EXP 6480464 [2 more ... CTD PMID:18444175 and PMID:18790785 methylseleninic acid increases cleavage EXP 6480464 [methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein and methylselenic acid results in increased cleavage of CASP8 protein CTD PMID:18790785 metiram multiple interactions EXP 6480464 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 mRNA and [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 protein CTD PMID:32800223 mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Fluvastatin results in increased activity of CASP8 protein] CTD PMID:24964743 microcystin-LR increases expression ISO Casp8 (Mus musculus) 6480464 cyanoginosin LR results in increased expression of CASP8 mRNA and cyanoginosin LR results in increased expression of CASP8 protein CTD PMID:23454832 and PMID:23891578 mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]] and Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]] CTD PMID:12645856 and PMID:17070682 minocycline multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Minocycline inhibits the reaction [HTT protein mutant form results in increased activity of CASP8 protein] more ... CTD PMID:12930891 more ... minocycline decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Minocycline results in decreased expression of CASP8 mRNA CTD PMID:14998631 mitomycin C multiple interactions EXP 6480464 Mitomycin results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:12181741 mitomycin C increases activity EXP 6480464 Mitomycin results in increased activity of CASP8 protein CTD PMID:10960761 more ... mitomycin C increases cleavage EXP 6480464 Mitomycin results in increased cleavage of CASP8 protein CTD PMID:16019139 and PMID:17021654 mitoxantrone increases activity EXP 6480464 Mitoxantrone results in increased activity of CASP8 protein CTD PMID:12948851 mitoxantrone increases activity ISO Casp8 (Mus musculus) 6480464 Mitoxantrone results in increased activity of CASP8 protein CTD PMID:32894303 ML-7 multiple interactions EXP 6480464 [ML 7 co-treated with quinocetone] results in increased cleavage of CASP8 protein and ML 7 results in increased susceptibility to [quinocetone results in increased cleavage of CASP8 protein] CTD PMID:26446980 molybdenum atom increases activity EXP 6480464 Molybdenum analog results in increased activity of CASP8 protein CTD PMID:26391003 mono(2-ethylhexyl) phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP8 mRNA and epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP8 protein] CTD PMID:31884101 and PMID:37286014 mono(2-ethylhexyl) phthalate increases expression ISO Casp8 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of CASP8 protein CTD PMID:37286014 mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA CTD PMID:35861251 monobenzyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP8 mRNA CTD PMID:31884101 monobenzyl phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA CTD PMID:35861251 Monobutylphthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA CTD PMID:35861251 monoethyl phthalate multiple interactions ISO Casp8 (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP8 mRNA CTD PMID:31884101 monoethyl phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA CTD PMID:35861251 morphine multiple interactions EXP 6480464 ARRB2 protein inhibits the reaction [Morphine results in decreased expression of CASP8 protein alternative form] CTD PMID:19239323 morphine increases activity ISO Casp8 (Mus musculus) 6480464 Morphine results in increased activity of CASP8 protein CTD PMID:11590188 morphine increases activity EXP 6480464 Morphine results in increased activity of CASP8 protein CTD PMID:19070643 morphine decreases expression EXP 6480464 Morphine results in decreased expression of CASP8 protein alternative form CTD PMID:19239323 myricetin decreases expression EXP 6480464 myricetin results in decreased expression of CASP8 protein CTD PMID:29698783 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases activity EXP 6480464 N more ... CTD PMID:17979179 N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide multiple interactions EXP 6480464 N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide affects the localization of and results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15520213 N-(p-amylcinnamoyl)anthranilic acid multiple interactions EXP 6480464 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Cisplatin results in increased activity of CASP8 protein]] CTD PMID:35395232 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[cholix toxin more ... CTD PMID:16169029 more ... N-acetyl-L-cysteine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein] more ... CTD PMID:18791325 more ... N-acetyl-L-cysteine multiple interactions EXP 127284846 N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP8 protein in the stomach) RGD N-acetyl-L-cysteine multiple interactions ISO Casp8 (Mus musculus) 6480464 [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 mRNA]] more ... CTD PMID:20184945 more ... N-Acetyl-S-(1,2-dichlorovinyl)-cysteine affects expression EXP 6480464 S-1 and 2-dichlorovinyl-N-acetylcysteine affects the expression of CASP8 mRNA CTD PMID:16844155 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15498850 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases activity ISO Casp8 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP8 protein CTD PMID:20100472 and PMID:20449726 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Casp8 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]] more ... CTD PMID:15914627 and PMID:20671745 N-methyl-4-phenylpyridinium increases activity ISO Casp8 (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in increased activity of CASP8 protein CTD PMID:33127410 N-methyl-4-phenylpyridinium multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Copper Sulfate inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP8 protein] CTD PMID:33127410 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein more ... CTD PMID:16030430 N-methyl-N-nitrosourea multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased activity of CASP8 protein and [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP8 mRNA CTD PMID:20732338 and PMID:22465879 N-methyl-N-nitrosourea increases expression ISO Casp8 (Rattus norvegicus) 6480464 Methylnitrosourea results in increased expression of CASP8 mRNA CTD PMID:28688903 N-nitrosodiethylamine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [3 more ... CTD PMID:18544905 more ... N-nitrosodiethylamine decreases activity ISO Casp8 (Mus musculus) 6480464 Diethylnitrosamine results in decreased activity of CASP8 protein CTD PMID:31067004 N-nitrosodiethylamine multiple interactions ISO Casp8 (Mus musculus) 6480464 S-allylcysteine inhibits the reaction [Diethylnitrosamine results in decreased activity of CASP8 protein] CTD PMID:31067004 N-nitrosomorpholine increases expression ISO Casp8 (Rattus norvegicus) 6480464 N-nitrosomorpholine results in increased expression of CASP8 protein CTD PMID:15816005 nelfinavir increases activity EXP 6480464 Nelfinavir results in increased activity of CASP8 protein CTD PMID:20105315 neohesperidin dihydrochalcone multiple interactions ISO Casp8 (Mus musculus) 6480464 neohesperidin dihydrochalcone inhibits the reaction [Carbon Tetrachloride results in increased expression of CASP8 protein] CTD PMID:24530446 nickel atom increases expression EXP 6480464 Nickel results in increased expression of CASP8 mRNA CTD PMID:21054559 nickel atom increases expression ISO Casp8 (Rattus norvegicus) 6480464 Nickel analog results in increased expression of CASP8 mRNA CTD PMID:27257140 nickel atom increases cleavage EXP 6480464 Nickel results in increased cleavage of CASP8 protein CTD PMID:24840272 nickel atom multiple interactions EXP 6480464 [cobalt ferrite binds to Nickel] which results in increased expression of CASP8 protein modified form more ... CTD PMID:23638002 more ... nickel dichloride affects expression ISO Casp8 (Rattus norvegicus) 6480464 nickel chloride affects the expression of CASP8 mRNA CTD PMID:22546817 niclosamide increases cleavage EXP 6480464 Niclosamide results in increased cleavage of CASP8 protein CTD PMID:35115509 nicotine affects expression ISO Casp8 (Rattus norvegicus) 6480464 Nicotine affects the expression of CASP8 mRNA CTD PMID:20426880 Niflumic acid multiple interactions EXP 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased activity of CASP8 protein]] more ... CTD PMID:21067863 Niflumic acid increases activity EXP 6480464 Niflumic Acid results in increased activity of CASP8 protein CTD PMID:21067863 nifuroxazide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP8 protein] CTD PMID:29606028 nimesulide multiple interactions EXP 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP8 protein] more ... CTD PMID:19360361 and PMID:21745461 nimustine increases cleavage EXP 6480464 Nimustine results in increased cleavage of CASP8 protein CTD PMID:26418950 nitric oxide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Nitric Oxide results in decreased cleavage of and results in decreased activity of CASP8 protein CTD PMID:10358093 nitric oxide multiple interactions ISO Casp8 (Mus musculus) 6480464 [Nitroprusside results in increased abundance of Nitric Oxide] which results in increased activity of CASP8 protein CTD PMID:22878015 nitric oxide increases activity EXP 6480464 Nitric Oxide results in increased activity of CASP8 protein CTD PMID:15126337 nitroprusside increases activity ISO Casp8 (Rattus norvegicus) 6480464 Nitroprusside results in increased activity of CASP8 protein CTD PMID:18311796 nitroprusside multiple interactions ISO Casp8 (Mus musculus) 6480464 [Nitroprusside results in increased abundance of Nitric Oxide] which results in increased activity of CASP8 protein CTD PMID:22878015 nitroprusside multiple interactions EXP 6480464 Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein] CTD PMID:16374551 nitroprusside multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 cilostazol inhibits the reaction [Nitroprusside results in increased activity of CASP8 protein] CTD PMID:18311796 nobiletin increases cleavage EXP 6480464 nobiletin results in increased cleavage of CASP8 protein CTD PMID:33058988 nobiletin multiple interactions EXP 6480464 AGN 193109 inhibits the reaction [nobiletin results in increased cleavage of CASP8 protein] CTD PMID:33058988 nocodazole multiple interactions EXP 6480464 Caspase Inhibitors inhibits the reaction [Nocodazole analog results in increased expression of CASP8 protein modified form] CTD PMID:28412508 nocodazole increases cleavage EXP 6480464 Nocodazole analog results in increased cleavage of CASP8 protein CTD PMID:28412508 Nodularin increases expression EXP 6480464 nodularin results in increased expression of CASP8 mRNA CTD PMID:27061667 Nodularin multiple interactions EXP 6480464 sauchinone inhibits the reaction [nodularin results in increased expression of CASP8 mRNA] CTD PMID:27061667 Nodularin increases activity ISO Casp8 (Rattus norvegicus) 6480464 nodularin results in increased activity of CASP8 protein CTD PMID:25192816 NORCANTHARIDIN multiple interactions EXP 6480464 Paclitaxel promotes the reaction [norcantharidin results in increased expression of CASP8 protein modified form] and U 0126 inhibits the reaction [norcantharidin results in increased expression of CASP8 protein modified form] CTD PMID:29193574 and PMID:34272796 NORCANTHARIDIN increases activity EXP 6480464 norcantharidin results in increased activity of CASP8 protein CTD PMID:20040369 and PMID:21266192 NORCANTHARIDIN increases expression EXP 6480464 norcantharidin results in increased expression of CASP8 protein modified form CTD PMID:29193574 and PMID:34272796 norfloxacin affects activity EXP 6480464 Norfloxacin affects the activity of CASP8 protein CTD PMID:32320760 notoginsenoside R1 multiple interactions ISO Casp8 (Mus musculus) 6480464 notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP8 protein] CTD PMID:23170834 NS-398 increases activity EXP 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CASP8 protein CTD PMID:12414664 Nutlin-3 multiple interactions EXP 6480464 nutlin 3 results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:16014563 nystatin multiple interactions EXP 6480464 Nystatin inhibits the reaction [resveratrol affects the localization of CASP8 protein] CTD PMID:12902349 Obacunone increases cleavage EXP 6480464 obacunone results in increased cleavage of CASP8 protein CTD PMID:25592883 Obacunone decreases expression EXP 6480464 obacunone results in decreased expression of CASP8 protein CTD PMID:21333732 obeticholic acid increases expression EXP 6480464 obeticholic acid results in increased expression of CASP8 mRNA CTD PMID:27939613 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of CASP8 mRNA CTD PMID:17316727 and PMID:24755393 ochratoxin A increases activity EXP 6480464 ochratoxin A results in increased activity of CASP8 protein CTD PMID:27193732 okadaic acid multiple interactions EXP 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Okadaic Acid results in increased cleavage of and results in increased activity of CASP8 protein] more ... CTD PMID:19084044 and PMID:23288922 okadaic acid decreases expression EXP 6480464 Okadaic Acid results in decreased expression of CASP8 mRNA CTD PMID:31926150 okadaic acid increases activity EXP 6480464 Okadaic Acid results in increased activity of CASP8 protein CTD PMID:31926150 okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of CASP8 protein modified form CTD PMID:31926150 olaparib multiple interactions EXP 6480464 [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein more ... CTD PMID:25531448 and PMID:26544897 oleandrin increases activity EXP 6480464 oleandrin results in increased activity of CASP8 protein CTD PMID:24172227 oleanolic acid increases activity EXP 6480464 Oleanolic Acid results in increased activity of CASP8 protein CTD PMID:20005942 oleanolic acid multiple interactions EXP 6480464 [Oleanolic Acid results in increased susceptibility to Doxorubicin] which affects the expression of CASP8 mRNA CTD PMID:37345903 omeprazole increases cleavage EXP 6480464 Omeprazole analog results in increased cleavage of CASP8 protein CTD PMID:18336733 omethoate decreases expression EXP 6480464 dimethoxon results in decreased expression of CASP8 mRNA CTD PMID:26688254 orlistat multiple interactions EXP 6480464 orlistat analog results in increased cleavage of and results in increased activity of CASP8 protein and orlistat results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:18796435 and PMID:20577697 orlistat multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Orlistat inhibits the reaction [Dietary Fats results in increased expression of CASP8 mRNA] CTD PMID:32450208 oroxylin A increases cleavage EXP 6480464 5 and 7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased cleavage of CASP8 protein CTD PMID:19135124 osthole increases cleavage EXP 6480464 osthol results in increased cleavage of CASP8 protein CTD PMID:29319219 ouabain multiple interactions EXP 6480464 Ouabain results in increased expression of and results in increased activity of CASP8 protein CTD PMID:31436044 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased cleavage of and results in increased activity of CASP8 protein more ... CTD PMID:19728331 ozone increases expression ISO Casp8 (Rattus norvegicus) 6480464 Ozone results in increased expression of CASP8 mRNA CTD PMID:35533050 p-chloromercuribenzoic acid increases expression EXP 6480464 p-Chloromercuribenzoic Acid results in increased expression of CASP8 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CASP8 mRNA CTD PMID:27188386 p-cresol multiple interactions EXP 6480464 SQSTM1 mutant form inhibits the reaction [4-cresol results in increased cleavage of CASP8 protein] CTD PMID:25668154 p-cresol increases cleavage EXP 6480464 4-cresol results in increased cleavage of CASP8 protein CTD PMID:25668154 p-menthan-3-ol decreases expression EXP 6480464 Menthol results in decreased expression of CASP8 mRNA CTD PMID:26760959 paclitaxel multiple interactions EXP 6480464 [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP8 protein more ... CTD PMID:14749477 more ... paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of CASP8 mRNA more ... CTD PMID:15907983 more ... paclitaxel increases activity EXP 6480464 Paclitaxel results in increased activity of CASP8 protein CTD PMID:11716366 paclitaxel increases expression ISO Casp8 (Mus musculus) 6480464 Paclitaxel results in increased expression of CASP8 mRNA CTD PMID:26091902 paclitaxel increases cleavage EXP 6480464 Paclitaxel results in increased cleavage of CASP8 protein CTD PMID:18071906 more ... Panduratin A increases cleavage EXP 6480464 panduratin A results in increased cleavage of CASP8 protein CTD PMID:16497706 panobinostat multiple interactions EXP 6480464 [Cisplatin co-treated with Panobinostat] affects the expression of CASP8 mRNA more ... CTD PMID:21791302 more ... panobinostat increases expression EXP 6480464 panobinostat results in increased expression of CASP8 mRNA CTD PMID:26272509 paracetamol affects expression ISO Casp8 (Mus musculus) 6480464 Acetaminophen affects the expression of CASP8 mRNA CTD PMID:17562736 paracetamol decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of CASP8 mRNA CTD PMID:33387578 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CASP8 mRNA CTD PMID:21420995 and PMID:29067470 paracetamol increases expression ISO Casp8 (Mus musculus) 6480464 Acetaminophen results in increased expression of CASP8 protein CTD PMID:12540782 paracetamol multiple interactions ISO Casp8 (Mus musculus) 6480464 [Acetaminophen co-treated with TNF protein] results in increased activity of CASP8 protein more ... CTD PMID:12085349 and PMID:12540782 paracetamol increases activity EXP 6480464 Acetaminophen results in increased activity of CASP8 CTD PMID:12005112 paraoxon multiple interactions ISO Casp8 (Mus musculus) 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Paraoxon results in increased cleavage of and results in increased activity of CASP8 protein] more ... CTD PMID:12831782 paraquat increases expression EXP 6480464 Paraquat results in increased expression of CASP8 mRNA and Paraquat results in increased expression of CASP8 mRNA alternative form CTD PMID:17064354 and PMID:20883675 paraquat increases expression ISO Casp8 (Rattus norvegicus) 6480464 Paraquat results in increased expression of CASP8 protein CTD PMID:35236239 paraquat increases cleavage EXP 6480464 Paraquat results in increased cleavage of CASP8 protein CTD PMID:28414160 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of CASP8 mRNA CTD PMID:26468117 paraquat multiple interactions EXP 6480464 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of CASP8 protein modified form] and Paraquat promotes the reaction [TNFRSF10B protein binds to CASP8 protein] CTD PMID:28414160 paraquat increases activity ISO Casp8 (Rattus norvegicus) 6480464 Paraquat results in increased activity of CASP8 protein CTD PMID:17561093 and PMID:24912633 paraquat multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 MIR136 promotes the reaction [Paraquat results in increased expression of CASP8 protein] more ... CTD PMID:17561093 and PMID:35236239 paroxetine increases activity ISO Casp8 (Mus musculus) 6480464 Paroxetine results in increased activity of CASP8 protein CTD PMID:28482088 Parthenin increases activity EXP 6480464 parthenin analog results in increased activity of CASP8 protein CTD PMID:25196075 parthenolide multiple interactions EXP 6480464 [[parthenolide results in decreased activity of RELA protein] which results in increased activity of CASP8 protein] which results in increased susceptibility to Tamoxifen and [parthenolide results in decreased activity of RELA protein] which results in increased activity of CASP8 protein CTD PMID:20154269 patulin increases activity EXP 6480464 Patulin results in increased activity of CASP8 protein CTD PMID:33577942 patulin multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [Patulin results in increased activity of CASP8 protein] CTD PMID:33577942 Pendulone increases activity EXP 6480464 pendulone results in increased activity of CASP8 protein CTD PMID:35288263 pentachlorophenol increases expression ISO Casp8 (Rattus norvegicus) 6480464 Pentachlorophenol results in increased expression of CASP8 mRNA CTD PMID:19442831 pentobarbital decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Pentobarbital results in decreased expression of CASP8 mRNA CTD PMID:16978161 Pentoxifylline multiple interactions EXP 6480464 Pentoxifylline promotes the reaction [TNFSF10 protein results in increased activity of CASP8 protein] CTD PMID:20804743 pepstatin A multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein] CTD PMID:28378122 perfluorohexanesulfonic acid increases expression ISO Casp8 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of CASP8 mRNA CTD PMID:37995155 perfluorononanoic acid decreases expression ISO Casp8 (Rattus norvegicus) 6480464 perfluoro-n-nonanoic acid results in decreased expression of CASP8 protein CTD PMID:19878704 perfluorononanoic acid increases activity ISO Casp8 (Rattus norvegicus) 6480464 perfluoro-n-nonanoic acid results in increased activity of CASP8 protein CTD PMID:19646514 perfluorooctane-1-sulfonic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CASP8 mRNA CTD PMID:36331819 perfluorooctanoic acid increases cleavage ISO Casp8 (Mus musculus) 6480464 perfluorooctanoic acid results in increased cleavage of CASP8 protein CTD PMID:37044272 perifosine multiple interactions EXP 6480464 [perifosine co-treated with Butyrates] results in increased activity of CASP8 protein more ... CTD PMID:15781658 and PMID:32587277 perifosine increases expression EXP 6480464 perifosine results in increased expression of CASP8 protein modified form CTD PMID:32587277 phenethyl caffeate multiple interactions ISO Casp8 (Mus musculus) 6480464 caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP8 protein] CTD PMID:18436364 phenethyl isothiocyanate increases activity EXP 6480464 phenethyl isothiocyanate results in increased activity of CASP8 protein CTD PMID:16054126 phenobarbital multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [3 more ... CTD PMID:27048571 phenol increases activity EXP 6480464 Phenol results in increased activity of CASP8 protein CTD PMID:23776099 phenylephrine affects activity EXP 6480464 Phenylephrine affects the activity of CASP8 protein CTD PMID:31605733 phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of CASP8 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CASP8 mRNA CTD PMID:27188386 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of CASP8 mRNA CTD PMID:20816883 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] more ... CTD PMID:12165276 more ... phosphatidylcholine multiple interactions EXP 6480464 [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CASP8 protein CTD PMID:21695227 phylloquinone multiple interactions EXP 6480464 [sorafenib co-treated with Vitamin K 1] results in increased cleavage of CASP8 protein CTD PMID:20301194 pifithrin-? multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 pifithrin inhibits the reaction [Doxorubicin results in increased activity of CASP8 protein] CTD PMID:16687611 pifithrin-? multiple interactions EXP 6480464 pifithrin inhibits the reaction [[Decitabine co-treated with Busulfan] results in increased activity of CASP8 protein] more ... CTD PMID:16777994 more ... Pinacidil decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Pinacidil results in decreased expression of CASP8 mRNA CTD PMID:17612592 pinostrobin increases expression EXP 6480464 pinostrobin results in increased expression of CASP8 mRNA CTD PMID:37208425 pirinixic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CASP8 mRNA more ... CTD PMID:17483499 and PMID:19710929 pirinixic acid increases expression ISO Casp8 (Mus musculus) 6480464 pirinixic acid results in increased expression of CASP8 mRNA CTD PMID:18301758 and PMID:23811191 pirinixic acid decreases expression ISO Casp8 (Mus musculus) 6480464 pirinixic acid results in decreased expression of CASP8 protein CTD PMID:17483499 platycodin D increases activity EXP 6480464 platycodin D results in increased activity of CASP8 protein CTD PMID:16631160 and PMID:20412017 plumbagin increases activity ISO Casp8 (Mus musculus) 6480464 plumbagin results in increased activity of CASP8 protein CTD PMID:20576514 plumbagin multiple interactions ISO Casp8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [plumbagin results in increased activity of CASP8 protein] CTD PMID:20576514 poly(I:C) increases activity EXP 6480464 Poly I-C results in increased activity of CASP8 protein CTD PMID:21418039 poly(I:C) multiple interactions EXP 6480464 arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP8 protein] and Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP8 protein] CTD PMID:21418039 pomalidomide multiple interactions EXP 6480464 [afuresertib co-treated with pomalidomide co-treated with Dexamethasone] results in increased cleavage of CASP8 protein CTD PMID:29928335 porphyrins increases expression EXP 6480464 Porphyrins results in increased expression of CASP8 mRNA CTD PMID:26468117 potassium chromate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CASP8 mRNA CTD PMID:22079256 potassium chromate decreases expression EXP 6480464 potassium chromate(VI) results in decreased expression of CASP8 mRNA CTD PMID:22079256 Pranoprofen increases activity EXP 6480464 pyranoprofen results in increased activity of CASP8 protein CTD PMID:31765691 prazosin increases activity EXP 6480464 Prazosin results in increased activity of CASP8 protein CTD PMID:26449523 prodigiosin increases cleavage EXP 6480464 Prodigiosin results in increased cleavage of CASP8 protein CTD PMID:15746575 prodigiosin increases activity EXP 6480464 Prodigiosin results in increased activity of CASP8 protein CTD PMID:31077745 progesterone increases expression ISO Casp8 (Mus musculus) 6480464 Progesterone results in increased expression of CASP8 mRNA CTD PMID:21549006 progesterone multiple interactions EXP 6480464 Progesterone inhibits the reaction [Cisplatin results in increased activity of CASP8 protein] CTD PMID:23482746 progesterone increases expression ISO Casp8 (Rattus norvegicus) 6480464 Progesterone results in increased expression of CASP8 mRNA CTD PMID:21770760 progesterone multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased activity of CASP8 protein and [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP8 mRNA CTD PMID:20732338 and PMID:22465879 propylparaben increases expression EXP 6480464 propylparaben results in increased expression of CASP8 mRNA and propylparaben results in increased expression of CASP8 protein CTD PMID:24481588 prostaglandin E2 multiple interactions ISO Casp8 (Mus musculus) 6480464 Dinoprostone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased cleavage of CASP8 protein]] CTD PMID:25432964 protoporphyrin decreases activity EXP 6480464 protoporphyrin IX results in decreased activity of CASP8 protein CTD PMID:16051694 psoralen multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased activity of CASP8 protein] CTD PMID:31364909 psoralen increases activity EXP 6480464 Ficusin results in increased activity of CASP8 protein CTD PMID:31364909 Psymberin increases response to substance EXP 6480464 CASP8 protein results in increased susceptibility to psymberin CTD PMID:20920557 pterostilbene multiple interactions ISO Casp8 (Mus musculus) 6480464 pterostilbene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:20681671 puerarin multiple interactions EXP 6480464 arsenic trioxide promotes the reaction [puerarin results in increased expression of CASP8 protein] CTD PMID:20416161 puerarin increases expression EXP 6480464 puerarin results in increased expression of CASP8 protein CTD PMID:20416161 Punicalagin increases expression EXP 6480464 punicalagin results in increased expression of CASP8 protein CTD PMID:28709945 Pyridostigmine bromide multiple interactions EXP 6480464 SOD2 protein SNP affects the reaction [Pyridostigmine Bromide affects the expression of CASP8 mRNA] CTD PMID:31175926 Pyridostigmine bromide decreases expression EXP 6480464 Pyridostigmine Bromide results in decreased expression of CASP8 protein CTD PMID:31175926 Pyridostigmine bromide affects expression EXP 6480464 Pyridostigmine Bromide affects the expression of CASP8 mRNA CTD PMID:31175926 pyridoxine increases expression EXP 6480464 Pyridoxine results in increased expression of CASP8 mRNA CTD PMID:28716455 pyrimethamine increases activity EXP 6480464 Pyrimethamine results in increased activity of CASP8 protein CTD PMID:18593930 pyrogallol increases activity EXP 6480464 Pyrogallol results in increased activity of CASP8 protein CTD PMID:19000662 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] more ... CTD PMID:15477007 quercetin multiple interactions ISO Casp8 (Mus musculus) 6480464 Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]] CTD PMID:15914627 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of CASP8 mRNA CTD PMID:30152185 quercetin increases expression EXP 6480464 Quercetin results in increased expression of CASP8 protein CTD PMID:25339540 quercetin increases cleavage EXP 6480464 Quercetin results in increased cleavage of CASP8 protein CTD PMID:18455702 more ... quercetin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased cleavage of CASP8 protein] more ... CTD PMID:17548900 more ... quercetin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Chlorpyrifos results in increased expression of CASP8 protein] more ... CTD PMID:16647178 more ... quercetin increases activity EXP 6480464 Quercetin results in increased activity of CASP8 protein CTD PMID:16158945 more ... quercetin affects localization EXP 6480464 Quercetin affects the localization of CASP8 protein CTD PMID:17876056 quercetin 3-O-beta-D-glucofuranoside decreases expression EXP 6480464 isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 quercetin 3-O-beta-D-glucopyranoside decreases expression EXP 6480464 isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 quercitrin increases expression EXP 6480464 quercitrin results in increased expression of CASP8 mRNA CTD PMID:25193878 raloxifene increases expression EXP 6480464 Raloxifene Hydrochloride results in increased expression of CASP8 mRNA CTD PMID:29705353 raloxifene multiple interactions EXP 6480464 [Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of CASP8 mRNA CTD PMID:29705353 raloxifene decreases expression EXP 6480464 Raloxifene Hydrochloride results in decreased expression of CASP8 mRNA and Raloxifene Hydrochloride results in decreased expression of CASP8 protein CTD PMID:27999800 reactive oxygen species multiple interactions EXP 6480464 [[[[[Lithocholic Acid results in increased abundance of Reactive Oxygen Species] which results in increased localization of and results in increased activity of FAS protein] which results in increased activity of CASP8 protein] which results in increased cleavage of BID protein] which results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein more ... CTD PMID:19054763 and PMID:19464277 reactive oxygen species multiple interactions ISO Casp8 (Mus musculus) 6480464 [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 mRNA]] more ... CTD PMID:35833596 regorafenib increases activity EXP 6480464 regorafenib results in increased activity of CASP8 protein CTD PMID:30801954 reserpine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP8 protein] CTD PMID:19463876 reserpine increases activity ISO Casp8 (Rattus norvegicus) 6480464 Reserpine results in increased activity of CASP8 protein CTD PMID:19463876 resveratrol multiple interactions EXP 6480464 [2 more ... CTD PMID:12902349 more ... resveratrol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Resveratrol inhibits the reaction [MIR136 promotes the reaction [Paraquat results in increased expression of CASP8 protein]] and Resveratrol inhibits the reaction [Paraquat results in increased expression of CASP8 protein] CTD PMID:35236239 resveratrol increases expression EXP 6480464 Resveratrol results in increased expression of CASP8 mRNA CTD PMID:29705353 resveratrol decreases expression ISO Casp8 (Rattus norvegicus) 6480464 resveratrol results in decreased expression of CASP8 protein modified form CTD PMID:24040416 resveratrol increases activity ISO Casp8 (Rattus norvegicus) 6480464 resveratrol results in increased activity of CASP8 protein CTD PMID:24534837 and PMID:24669252 resveratrol multiple interactions ISO Casp8 (Mus musculus) 6480464 resveratrol inhibits the reaction [Isoflurane results in increased activity of CASP8 protein] CTD PMID:23922164 resveratrol increases activity EXP 6480464 [resveratrol results in increased activity of CASP8 protein] which results in increased activity of CASP3 protein more ... CTD PMID:18276737 more ... resveratrol increases cleavage EXP 6480464 resveratrol results in increased cleavage of CASP8 protein CTD PMID:18347188 and PMID:22923501 resveratrol affects response to substance EXP 6480464 CASP8 protein affects the susceptibility to resveratrol CTD PMID:22923501 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of CASP8 protein CTD PMID:18089832 and PMID:19846903 resveratrol increases cleavage ISO Casp8 (Mus musculus) 6480464 resveratrol results in increased cleavage of CASP8 protein CTD PMID:17872969 resveratrol affects localization EXP 6480464 resveratrol affects the localization of CASP8 protein CTD PMID:12902349 resveratrol increases expression ISO Casp8 (Mus musculus) 6480464 resveratrol results in increased expression of CASP8 mRNA CTD PMID:22610192 resveratrol decreases activity EXP 6480464 resveratrol results in decreased activity of CASP8 protein CTD PMID:12925042 Rhein increases cleavage EXP 6480464 rhein results in increased cleavage of CASP8 protein CTD PMID:31436023 ribavirin multiple interactions EXP 6480464 Ribavirin promotes the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:12760867 riboflavin increases activity ISO Casp8 (Mus musculus) 6480464 Riboflavin analog results in increased activity of CASP8 protein CTD PMID:20688149 rifampicin multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]] and Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:11958592 and PMID:12645856 Riluzole increases activity EXP 6480464 Riluzole results in increased activity of CASP8 protein CTD PMID:19528481 Risedronate sodium increases activity ISO Casp8 (Rattus norvegicus) 6480464 Risedronic Acid results in increased activity of CASP8 protein CTD PMID:19505369 Ro 31-8220 increases activity EXP 6480464 Ro 31-8220 results in increased activity of CASP8 protein CTD PMID:18054255 rolipram multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Rolipram inhibits the reaction [Manganese results in increased activity of CASP8 protein] CTD PMID:31161640 rosmarinic acid increases activity EXP 6480464 Rosmarinic Acid results in increased activity of CASP8 protein CTD PMID:36863647 rosmarinic acid increases expression EXP 6480464 Rosmarinic Acid results in increased expression of CASP8 mRNA CTD PMID:36863647 rotenone increases expression ISO Casp8 (Mus musculus) 6480464 Rotenone results in increased expression of CASP8 mRNA CTD PMID:23186747 rotenone increases expression ISO Casp8 (Rattus norvegicus) 6480464 Rotenone results in increased expression of CASP8 protein CTD PMID:25502462 rotenone multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Ursodeoxycholic Acid inhibits the reaction [Rotenone results in increased expression of CASP8 protein] CTD PMID:25502462 rotenone multiple interactions ISO Casp8 (Mus musculus) 6480464 Rotenone inhibits the reaction [[lipopolysaccharide and E coli O55-B5 co-treated with Galactosamine] results in increased activity of CASP8 protein] CTD PMID:24830863 rubimaillin increases activity EXP 6480464 rubimaillin results in increased activity of CASP8 protein CTD PMID:19716835 rubimaillin multiple interactions EXP 6480464 BCL2L1 protein inhibits the reaction [rubimaillin results in increased activity of CASP8 protein] and benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [rubimaillin results in increased activity of CASP8 protein] CTD PMID:19716835 rubitecan multiple interactions EXP 6480464 [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CASP8 protein CTD PMID:21695227 rubitecan increases expression EXP 6480464 rubitecan results in increased expression of CASP8 protein CTD PMID:21695227 rutin multiple interactions ISO Casp8 (Mus musculus) 6480464 [Rutin binds to Zinc] which results in increased expression of CASP8 mRNA CTD PMID:26091902 rutin increases expression ISO Casp8 (Mus musculus) 6480464 Rutin results in increased expression of CASP8 mRNA CTD PMID:26091902 S-(1,2-dichlorovinyl)-L-cysteine increases activity EXP 6480464 S-(1 and 2-dichlorovinyl)cysteine results in increased activity of CASP8 protein CTD PMID:29129777 S-allylcysteine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] and S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] CTD PMID:16030430 S-allylcysteine increases activity EXP 6480464 S-allylcysteine results in increased activity of CASP8 protein CTD PMID:31067004 S-allylcysteine multiple interactions ISO Casp8 (Mus musculus) 6480464 [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP8 protein] more ... CTD PMID:22033380 and PMID:31067004 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [Buthionine Sulfoximine co-treated with arsenic trioxide] results in increased cleavage of CASP8 protein and pyrazolanthrone inhibits the reaction [[Buthionine Sulfoximine co-treated with arsenic trioxide] results in increased cleavage of CASP8 protein] CTD PMID:17145888 S-nitrosoglutathione increases activity EXP 6480464 S-Nitrosoglutathione results in increased activity of CASP8 protein CTD PMID:20153346 safrole increases expression EXP 6480464 Safrole results in increased expression of CASP8 mRNA CTD PMID:21591240 Salinomycin decreases expression EXP 6480464 salinomycin results in decreased expression of CASP8 mRNA CTD PMID:19682730 Salmeterol xinafoate multiple interactions EXP 6480464 [Fluticasone co-treated with Salmeterol Xinafoate] results in increased activity of CASP8 protein CTD PMID:15536434 sanguinarine increases activity EXP 6480464 sanguinarine results in increased activity of CASP8 protein CTD PMID:19346183 and PMID:23660334 sanguinarine multiple interactions EXP 6480464 [sanguinarine co-treated with Arsenic Trioxide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein more ... CTD PMID:24345465 sappanchalcone increases cleavage EXP 6480464 sappanchalcone results in increased cleavage of CASP8 protein CTD PMID:32590072 SB 203580 multiple interactions EXP 6480464 [Resveratrol co-treated with SB 203580] results in increased activity of CASP8 protein more ... CTD PMID:22644961 more ... SB 415286 multiple interactions EXP 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:15475000 and PMID:15942663 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Se-methyl-L-selenocysteine increases expression EXP 6480464 selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 Se-methylselenocysteine increases expression EXP 6480464 selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 selenium atom multiple interactions EXP 6480464 [Doxorubicin co-treated with Selenium] promotes the reaction [FADD protein binds to CASP8 protein] more ... CTD PMID:17970047 and PMID:27920530 selenium atom increases activity EXP 6480464 Selenium results in increased activity of CASP8 protein CTD PMID:12432279 selenium atom decreases expression EXP 6480464 Selenium results in decreased expression of CASP8 mRNA CTD PMID:19244175 selenocystine decreases expression EXP 6480464 selenocystine results in decreased expression of CASP8 protein CTD PMID:35863474 selumetinib multiple interactions EXP 6480464 AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of CASP8 protein]] CTD PMID:27222248 senecionine multiple interactions EXP 6480464 senecionine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 Senkirkine increases cleavage EXP 6480464 senkirkine results in increased cleavage of CASP8 protein CTD PMID:29458164 Sesamol increases activity EXP 6480464 sesamol results in increased activity of CASP8 protein CTD PMID:27270451 sesquiterpene increases activity EXP 6480464 Sesquiterpenes results in increased activity of CASP8 protein CTD PMID:18070620 silibinin multiple interactions EXP 6480464 benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP8 protein] more ... CTD PMID:16777994 simvastatin increases activity EXP 6480464 Simvastatin results in increased activity of CASP8 protein CTD PMID:15705602 simvastatin multiple interactions EXP 6480464 Simvastatin results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:21910007 simvastatin increases cleavage EXP 6480464 Simvastatin results in increased cleavage of CASP8 protein CTD PMID:12962723 and PMID:20464445 simvastatin increases activity ISO Casp8 (Mus musculus) 6480464 Simvastatin results in increased activity of CASP8 protein CTD PMID:20883752 simvastatin multiple interactions ISO Casp8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP8 protein] CTD PMID:20883752 sirolimus multiple interactions EXP 6480464 [7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of CASP8 protein more ... CTD PMID:15767555 more ... sirolimus multiple interactions ISO Casp8 (Mus musculus) 6480464 Sirolimus inhibits the reaction [TGFB1 protein inhibits the reaction [Cadmium Chloride results in increased expression of CASP8 protein]] CTD PMID:28342888 sirolimus increases cleavage EXP 6480464 Sirolimus results in increased cleavage of CASP8 protein CTD PMID:25307878 sodium arsenite increases activity ISO Casp8 (Mus musculus) 6480464 sodium arsenite results in increased activity of CASP8 protein CTD PMID:16421179 and PMID:20006689 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CASP8 protein CTD PMID:34861471 sodium arsenite increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 sodium arsenite results in increased cleavage of CASP8 protein CTD PMID:35939230 sodium arsenite increases cleavage ISO Casp8 (Mus musculus) 6480464 sodium arsenite results in increased cleavage of CASP8 protein CTD PMID:29854073 sodium arsenite multiple interactions EXP 6480464 [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP8 protein more ... CTD PMID:30125548 more ... sodium arsenite decreases methylation EXP 6480464 sodium arsenite results in decreased methylation of CASP8 gene CTD PMID:25199682 sodium arsenite increases cleavage EXP 6480464 sodium arsenite results in increased cleavage of CASP8 protein CTD PMID:24100277 and PMID:29039521 sodium arsenite multiple interactions ISO Casp8 (Mus musculus) 6480464 [Mercuric Chloride co-treated with sodium arsenite co-treated with Cadmium Chloride] results in increased activity of CASP8 protein and salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP8 protein] CTD PMID:16421179 and PMID:29854073 sodium arsenite increases expression ISO Casp8 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of CASP8 protein CTD PMID:20946910 sodium arsenite increases activity ISO Casp8 (Rattus norvegicus) 6480464 sodium arsenite results in increased activity of CASP8 protein CTD PMID:20946910 sodium arsenite decreases expression ISO Casp8 (Mus musculus) 6480464 sodium arsenite results in decreased expression of CASP8 mRNA CTD PMID:14691202 sodium arsenite multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein] more ... CTD PMID:20946910 more ... sodium chloride increases expression EXP 6480464 Sodium Chloride results in increased expression of CASP8 mRNA CTD PMID:23634900 sodium chloride multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein more ... CTD PMID:16030430 sodium dichromate multiple interactions ISO Casp8 (Mus musculus) 6480464 CAT protein inhibits the reaction [sodium bichromate results in increased degradation of CASP8 protein] and TRP53 mutant form inhibits the reaction [sodium bichromate results in increased degradation of CASP8 protein] CTD PMID:20298709 sodium dichromate increases activity EXP 6480464 sodium bichromate results in increased activity of CASP8 protein CTD PMID:18544562 sodium dichromate increases degradation ISO Casp8 (Mus musculus) 6480464 sodium bichromate results in increased degradation of CASP8 protein CTD PMID:20298709 sodium disulfite multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 GHRL protein inhibits the reaction [sodium metabisulfite results in increased activity of CASP8 protein] CTD PMID:25486021 sodium disulfite increases activity ISO Casp8 (Rattus norvegicus) 6480464 sodium metabisulfite results in increased activity of CASP8 protein CTD PMID:25486021 sodium disulfite increases expression EXP 6480464 sodium metabisulfite results in increased expression of CASP8 mRNA CTD PMID:33957602 sodium fluoride multiple interactions EXP 6480464 Sodium Fluoride results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:21708216 sodium fluoride increases cleavage ISO Casp8 (Mus musculus) 6480464 Sodium Fluoride results in increased cleavage of CASP8 protein CTD PMID:30130527 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of CASP8 mRNA CTD PMID:19852076 sodium propionate multiple interactions ISO Casp8 (Mus musculus) 6480464 sodium propionate inhibits the reaction [Ethanol results in increased expression of CASP8 mRNA] CTD PMID:35639301 Sodium salicylate increases activity ISO Casp8 (Rattus norvegicus) 6480464 Sodium Salicylate results in increased activity of CASP8 protein CTD PMID:17561093 Sodium salicylate multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Sodium Salicylate inhibits the reaction [Paraquat results in increased activity of CASP8 protein] CTD PMID:17561093 sorafenib multiple interactions EXP 6480464 [sorafenib co-treated with TNFSF10 protein] promotes the reaction [CASP8 protein modified form results in increased cleavage of BID protein] more ... CTD PMID:16007148 more ... sorafenib increases cleavage EXP 6480464 sorafenib results in increased cleavage of CASP8 protein CTD PMID:18200035 sorafenib affects localization EXP 6480464 sorafenib affects the localization of CASP8 protein modified form CTD PMID:17909059 spermine multiple interactions ISO Casp8 (Mus musculus) 6480464 Spermine inhibits the reaction [Dexamethasone results in increased activity of CASP8 protein] CTD PMID:11399061 spironolactone multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Testosterone inhibits the reaction [Sorbitol results in increased activity of CASP8 protein]] CTD PMID:20609311 Spiruchostatin A increases activity EXP 6480464 spiruchostatin A results in increased activity of CASP8 protein CTD PMID:25078973 spiruchostatin B increases activity EXP 6480464 spiruchostatin B results in increased activity of CASP8 protein CTD PMID:25078973 staurosporine multiple interactions EXP 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Staurosporine results in increased cleavage of CASP8 protein] and Staurosporine results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:16007152 and PMID:24658017 staurosporine increases cleavage EXP 6480464 Staurosporine results in increased cleavage of CASP8 protein CTD PMID:24658017 staurosporine increases activity EXP 6480464 Staurosporine results in increased activity of CASP8 protein CTD PMID:19352495 more ... streptozocin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein] more ... CTD PMID:23267840 more ... streptozocin increases activity ISO Casp8 (Rattus norvegicus) 6480464 Streptozocin results in increased activity of CASP8 protein CTD PMID:29606028 streptozocin increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Streptozocin results in increased cleavage of CASP8 protein CTD PMID:25541178 streptozocin increases expression ISO Casp8 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of CASP8 mRNA and Streptozocin results in increased expression of CASP8 protein CTD PMID:23267840 and PMID:28856781 styrene increases activity ISO Casp8 (Rattus norvegicus) 6480464 Styrene results in increased activity of CASP8 protein CTD PMID:17420221 Suillin multiple interactions EXP 6480464 suillin results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:19616521 sulforaphane multiple interactions EXP 6480464 [sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP8 protein and sulforaphane results in increased expression of and results in increased activity of CASP8 protein CTD PMID:26833863 and PMID:29792947 sulforaphane increases expression EXP 6480464 sulforaphane results in increased expression of CASP8 mRNA CTD PMID:31838189 sulfur dioxide increases expression ISO Casp8 (Rattus norvegicus) 6480464 Sulfur Dioxide results in increased expression of CASP8 mRNA CTD PMID:19621461 and PMID:35533050 sulfur dioxide multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA CTD PMID:31268311 sulfur dioxide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form] and Sulfur Dioxide results in increased expression of and results in increased activity of CASP8 protein CTD PMID:19621461 and PMID:30503585 sulindac multiple interactions EXP 6480464 [Sulindac co-treated with TNFSF10 protein] results in increased activity of CASP8 protein CTD PMID:21171083 sulindac sulfide multiple interactions EXP 6480464 BAX protein affects the reaction [TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP8 protein]] more ... CTD PMID:12203115 and PMID:12414664 sulindac sulfide increases activity ISO Casp8 (Mus musculus) 6480464 sulindac sulfide results in increased activity of CASP8 protein CTD PMID:16886631 sulindac sulfide increases activity EXP 6480464 sulindac sulfide results in increased activity of CASP8 protein CTD PMID:11559570 and PMID:12414664 sulindac sulfone increases activity EXP 6480464 sulindac sulfone results in increased activity of CASP8 protein CTD PMID:11559570 swainsonine increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Swainsonine results in increased cleavage of CASP8 protein CTD PMID:33186601 syringic acid increases expression EXP 6480464 syringic acid results in increased expression of CASP8 mRNA CTD PMID:33759321 T-2 toxin increases expression ISO Casp8 (Rattus norvegicus) 6480464 T-2 Toxin results in increased expression of CASP8 mRNA CTD PMID:26141394 more ... T-2 toxin increases activity ISO Casp8 (Mus musculus) 6480464 T-2 Toxin results in increased activity of CASP8 protein CTD PMID:29432840 T-2 toxin increases expression ISO Casp8 (Mus musculus) 6480464 T-2 Toxin results in increased expression of CASP8 mRNA CTD PMID:29432840 T-2 toxin multiple interactions ISO Casp8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein] CTD PMID:29432840 tacedinaline multiple interactions EXP 6480464 tacedinaline promotes the reaction [Decitabine results in increased expression of CASP8 protein] CTD PMID:21771726 tacrolimus hydrate multiple interactions EXP 6480464 Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:15548389 tacrolimus hydrate increases expression ISO Casp8 (Mus musculus) 6480464 Tacrolimus results in increased expression of CASP8 protein CTD PMID:27606422 tamoxifen multiple interactions EXP 6480464 [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein more ... CTD PMID:17767197 more ... tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of CASP8 protein CTD PMID:17767197 tanespimycin multiple interactions EXP 6480464 [tanespimycin co-treated with Sirolimus] results in increased cleavage of CASP8 protein CTD PMID:17121904 tanespimycin increases cleavage EXP 6480464 tanespimycin results in increased cleavage of CASP8 protein CTD PMID:17121904 tangeretin increases cleavage EXP 6480464 tangeretin results in increased cleavage of CASP8 protein CTD PMID:33058988 tangeretin multiple interactions EXP 6480464 AGN 193109 inhibits the reaction [tangeretin results in increased cleavage of CASP8 protein] CTD PMID:33058988 Tanshinone I multiple interactions EXP 6480464 tanshinone promotes the reaction [TNFSF10 protein results in increased cleavage of CASP8 protein] CTD PMID:26203587 taurocholic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Taurocholic Acid inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP8 protein] CTD PMID:12388182 tellurium atom decreases activity ISO Casp8 (Rattus norvegicus) 6480464 Tellurium results in decreased activity of CASP8 protein CTD PMID:18571097 temozolomide multiple interactions EXP 6480464 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 mRNA more ... CTD PMID:21514314 and PMID:32800223 temozolomide increases cleavage EXP 6480464 temozolomide results in increased cleavage of CASP8 protein CTD PMID:26418950 Terfenadine increases activity EXP 6480464 Terfenadine results in increased activity of CASP8 protein CTD PMID:16569656 Terfenadine increases activity ISO Casp8 (Rattus norvegicus) 6480464 Terfenadine results in increased activity of CASP8 protein CTD PMID:15288570 Terfenadine increases cleavage EXP 6480464 Terfenadine results in increased cleavage of CASP8 protein CTD PMID:20570632 tert-butyl hydroperoxide multiple interactions EXP 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA more ... CTD PMID:35690295 testosterone multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Estradiol promotes the reaction [Testosterone inhibits the reaction [Corticosterone results in increased cleavage of CASP8 protein]] more ... CTD PMID:20609311 and PMID:29625166 testosterone increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Testosterone results in increased cleavage of CASP8 protein CTD PMID:24658017 tetrachloromethane multiple interactions ISO Casp8 (Mus musculus) 6480464 2 more ... CTD PMID:18291569 more ... tetrachloromethane increases cleavage ISO Casp8 (Mus musculus) 6480464 Carbon Tetrachloride results in increased cleavage of CASP8 protein CTD PMID:25432964 tetrachloromethane increases expression ISO Casp8 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of CASP8 protein CTD PMID:24530446 tetrachloromethane increases activity ISO Casp8 (Mus musculus) 6480464 Carbon Tetrachloride results in increased activity of CASP8 protein CTD PMID:18291569 and PMID:18436364 tetrachloromethane multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Taurocholic Acid inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP8 protein] CTD PMID:12388182 tetrachloromethane increases activity ISO Casp8 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased activity of CASP8 protein CTD PMID:12388182 tetramethylpyrazine multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 tetramethylpyrazine inhibits the reaction [Gentamicins results in increased activity of CASP8 protein] and tetramethylpyrazine inhibits the reaction [TNF protein promotes the reaction [Gentamicins results in increased expression of CASP8 protein]] CTD PMID:17132701 tetrathiomolybdate(2-) multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in increased cleavage of CASP8 protein and [Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of CASP8 protein CTD PMID:22276220 tetrazolium violet increases activity ISO Casp8 (Mus musculus) 6480464 tetrazolium violet results in increased activity of CASP8 protein CTD PMID:18547555 thalidomide increases cleavage EXP 6480464 Thalidomide analog results in increased cleavage of CASP8 protein CTD PMID:15858615 thalidomide decreases expression ISO Casp8 (Mus musculus) 6480464 Thalidomide results in decreased expression of CASP8 mRNA CTD PMID:26217789 thapsigargin increases activity ISO Casp8 (Mus musculus) 6480464 Thapsigargin results in increased activity of CASP8 protein CTD PMID:16018998 Theaflavin 3,3'-digallate increases activity EXP 6480464 theaflavin-3 and 3'-digallate results in increased activity of CASP8 protein CTD PMID:30769778 thiabendazole increases activity ISO Casp8 (Rattus norvegicus) 6480464 Thiabendazole results in increased activity of CASP8 protein CTD PMID:26748015 thiazoles multiple interactions EXP 6480464 [Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein and Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein] CTD PMID:19014919 thioacetamide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in decreased expression of CASP8 mRNA more ... CTD PMID:23830814 and PMID:29133031 thioacetamide decreases expression ISO Casp8 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of CASP8 mRNA CTD PMID:29133031 thiosalicylic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased activity of CASP8 protein CTD PMID:19427195 thymol increases activity EXP 6480464 Thymol results in increased activity of CASP8 protein CTD PMID:21640085 thymol multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA] CTD PMID:26996544 thymol sulfate(1-) multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA] CTD PMID:26996544 thymol sulfate(1-) increases activity EXP 6480464 Thymol results in increased activity of CASP8 protein CTD PMID:21640085 thymoquinone multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 thymoquinone inhibits the reaction [Ethanol results in increased cleavage of CASP8 protein] CTD PMID:29085585 tioguanine increases response to substance EXP 6480464 CASP8 protein results in increased susceptibility to Thioguanine CTD PMID:22010212 tioguanine increases expression EXP 6480464 Thioguanine results in increased expression of CASP8 protein CTD PMID:22010212 Tiron multiple interactions EXP 6480464 1 more ... CTD PMID:19481559 titanium dioxide increases expression ISO Casp8 (Rattus norvegicus) 6480464 titanium dioxide results in increased expression of CASP8 mRNA and titanium dioxide results in increased expression of CASP8 protein CTD PMID:34874108 titanium dioxide multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 carboxymethyl-chitosan inhibits the reaction [titanium dioxide results in increased expression of CASP8 mRNA] and carboxymethyl-chitosan inhibits the reaction [titanium dioxide results in increased expression of CASP8 protein] CTD PMID:34874108 Tomentosin decreases expression EXP 6480464 tomentosin results in decreased expression of CASP8 protein CTD PMID:30917517 Tomentosin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP8 protein] CTD PMID:30917517 topotecan multiple interactions EXP 6480464 [Amlodipine co-treated with Topotecan] results in increased activity of CASP8 protein and chrysin inhibits the reaction [Topotecan results in increased activity of CASP8 protein] CTD PMID:16516327 and PMID:20457140 topotecan increases activity EXP 6480464 Topotecan results in increased activity of CASP8 protein CTD PMID:20457140 tranilast multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 tranilast inhibits the reaction [Cisplatin results in increased expression of CASP8 protein] CTD PMID:34047436 trans-chalcone increases cleavage EXP 6480464 Chalcone results in increased cleavage of CASP8 protein CTD PMID:20620131 trans-chalcone multiple interactions EXP 6480464 MYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP8 protein] CTD PMID:20620131 triamcinolone acetonide increases activity ISO Casp8 (Rattus norvegicus) 6480464 Triamcinolone Acetonide results in increased activity of CASP8 protein CTD PMID:15987869 tributylstannane increases expression ISO Casp8 (Rattus norvegicus) 6480464 tributyltin results in increased expression of CASP8 protein CTD PMID:23743147 tributylstannane decreases expression ISO Casp8 (Rattus norvegicus) 6480464 tributyltin results in decreased expression of CASP8 protein CTD PMID:28707438 Tributyltin oxide increases expression ISO Casp8 (Mus musculus) 6480464 bis(tri-n-butyltin)oxide results in increased expression of CASP8 mRNA CTD PMID:25270620 Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of CASP8 mRNA CTD PMID:24247028 trichostatin A multiple interactions EXP 6480464 [[Decitabine co-treated with trichostatin A] affects the methylation of CASP8 promoter] which affects the expression of CASP8 mRNA more ... CTD PMID:15781658 more ... trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of CASP8 mRNA CTD PMID:24935251 and PMID:26272509 trifluridine increases cleavage EXP 6480464 Trifluridine results in increased cleavage of CASP8 protein CTD PMID:19816940 Triptolide multiple interactions ISO Casp8 (Mus musculus) 6480464 [triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP8 protein modified form and triptolide results in increased expression of and results in increased activity of CASP8 protein CTD PMID:26990902 and PMID:30633930 troglitazone increases activity EXP 6480464 troglitazone results in increased activity of CASP8 protein CTD PMID:14508522 troglitazone increases expression ISO Casp8 (Mus musculus) 6480464 troglitazone results in increased expression of CASP8 mRNA CTD PMID:28973697 troglitazone increases expression EXP 6480464 Troglitazone results in increased expression of CASP8 more ... CTD PMID:12680223 more ... troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of CASP8 mRNA CTD PMID:19631733 trovafloxacin multiple interactions EXP 6480464 [trovafloxacin co-treated with TNF protein] results in increased activity of CASP8 protein CTD PMID:24097668 ursodeoxycholic acid multiple interactions EXP 6480464 [oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased cleavage of and results in increased activity of CASP8 protein more ... CTD PMID:16432164 more ... ursodeoxycholic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Ursodeoxycholic Acid inhibits the reaction [Rotenone results in increased expression of CASP8 protein] CTD PMID:25502462 ursodeoxycholic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP8 protein] CTD PMID:21146893 ursodeoxycholic acid increases activity EXP 6480464 Ursodeoxycholic Acid results in increased activity of CASP8 protein CTD PMID:21362627 ursolic acid increases activity EXP 6480464 Ursolic Acid results in increased activity of CASP8 protein CTD PMID:20005942 valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:19006566 more ... valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of CASP8 mRNA and Valproic Acid results in increased expression of CASP8 protein CTD PMID:21771726 more ... valproic acid increases expression ISO Casp8 (Mus musculus) 6480464 Valproic Acid results in increased expression of CASP8 mRNA CTD PMID:24896083 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of CASP8 mRNA CTD PMID:25979313 valproic acid affects expression ISO Casp8 (Mus musculus) 6480464 Valproic Acid affects the expression of CASP8 mRNA CTD PMID:17292431 valproic acid increases cleavage EXP 6480464 Valproic Acid results in increased cleavage of CASP8 protein CTD PMID:19006566 vanillic acid multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA] CTD PMID:25794854 vemurafenib multiple interactions EXP 6480464 [KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of CASP8 protein] more ... CTD PMID:27222248 venom increases cleavage EXP 6480464 Viper Venoms results in increased cleavage of CASP8 protein CTD PMID:25417048 verapamil multiple interactions EXP 6480464 [Verapamil co-treated with gambogic acid] results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:24373880 vincristine increases expression EXP 6480464 Vincristine results in increased expression of CASP8 mRNA CTD PMID:16001973 vincristine increases response to substance EXP 6480464 CASP8 protein results in increased susceptibility to Vincristine CTD PMID:22010212 vincristine multiple interactions EXP 6480464 Vincristine results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:22010212 vorinostat multiple interactions EXP 6480464 [Bortezomib co-treated with Vorinostat] results in increased activity of CASP8 protein more ... CTD PMID:12893773 more ... vorinostat increases cleavage EXP 6480464 vorinostat results in increased cleavage of CASP8 protein CTD PMID:15897598 and PMID:17351739 vorinostat increases expression EXP 6480464 vorinostat results in increased expression of CASP8 mRNA CTD PMID:26272509 vorinostat increases activity EXP 6480464 vorinostat results in increased activity of CASP8 protein CTD PMID:15173093 more ... WIN 55212-2 decreases cleavage EXP 6480464 (3R)-((2 more ... CTD PMID:30776504 wogonin multiple interactions ISO Casp8 (Mus musculus) 6480464 wogonin inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased activity of CASP8 protein] CTD PMID:26756871 wortmannin multiple interactions EXP 6480464 ABT-737 promotes the reaction [Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]] and Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein] CTD PMID:20104024 wortmannin multiple interactions ISO Casp8 (Rattus norvegicus) 6480464 wortmannin inhibits the reaction [2 more ... CTD PMID:24726520 xanthohumol multiple interactions EXP 6480464 xanthohumol results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15995977 xanthohumol increases cleavage EXP 6480464 xanthohumol results in increased cleavage of CASP8 protein CTD PMID:35229981 xanthohumol increases activity EXP 6480464 xanthohumol results in increased activity of CASP8 protein CTD PMID:26297991 Y-27632 multiple interactions EXP 6480464 Y 27632 inhibits the reaction [TNF protein results in increased cleavage of CASP8 protein] CTD PMID:28743511 zearalenone increases cleavage ISO Casp8 (Rattus norvegicus) 6480464 Zearalenone results in increased cleavage of CASP8 protein CTD PMID:30600648 zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of CASP8 mRNA CTD PMID:30668976 zearalenone multiple interactions EXP 6480464 [Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA] more ... CTD PMID:30668976 zearalenone increases expression ISO Casp8 (Rattus norvegicus) 6480464 Zearalenone results in increased expression of CASP8 mRNA CTD PMID:30600648 zebularine increases activity EXP 6480464 pyrimidin-2-one beta-ribofuranoside results in increased activity of CASP8 protein CTD PMID:23320119 zidovudine increases cleavage EXP 6480464 Zidovudine results in increased cleavage of CASP8 protein CTD PMID:27238871 zidovudine multiple interactions EXP 6480464 Acrolein promotes the reaction [Zidovudine results in increased cleavage of CASP8 protein] and Zidovudine promotes the reaction [Acrolein results in increased cleavage of CASP8 protein] CTD PMID:27238871 zinc atom multiple interactions ISO Casp8 (Mus musculus) 6480464 [Rutin binds to Zinc] which results in increased expression of CASP8 mRNA CTD PMID:26091902 zinc oxide multiple interactions EXP 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Zinc Oxide analog results in increased activity of CASP8 protein] and Thioctic Acid inhibits the reaction [Zinc Oxide analog results in increased activity of CASP8 protein] CTD PMID:27544635 zinc oxide increases cleavage ISO Casp8 (Mus musculus) 6480464 Zinc Oxide analog results in increased cleavage of CASP8 protein CTD PMID:24614525 zinc oxide multiple interactions ISO Casp8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP8 protein] CTD PMID:24614525 zinc oxide increases activity EXP 6480464 Zinc Oxide analog results in increased activity of CASP8 protein CTD PMID:27544635 zinc protoporphyrin multiple interactions EXP 6480464 zinc protoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP8 protein] CTD PMID:16051694 zinc pyrithione increases activity EXP 6480464 pyrithione zinc results in increased activity of CASP8 protein CTD PMID:20151177 zinc pyrithione increases expression EXP 6480464 pyrithione zinc results in increased expression of CASP8 mRNA CTD PMID:21424779 zinc sulfate multiple interactions EXP 6480464 [gluconic acid co-treated with Zinc Sulfate] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA] and Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA] CTD PMID:27017951 zinc(0) multiple interactions ISO Casp8 (Mus musculus) 6480464 [Rutin binds to Zinc] which results in increased expression of CASP8 mRNA CTD PMID:26091902 ziram increases activity EXP 6480464 Ziram results in increased activity of CASP8 protein CTD PMID:22159898 zoledronic acid increases expression EXP 6480464 zoledronic acid results in increased expression of CASP8 mRNA CTD PMID:19036117 and PMID:20977926 zoledronic acid multiple interactions ISO Casp8 (Mus musculus) 6480464 [zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP8 protein CTD PMID:19789217
