Gene: ODC1 (ornithine decarboxylase 1)  Homo sapiens

Symbol: ODC1
Name: ornithine decarboxylase 1
Description: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ODC; ornithine decarboxylase; OTTHUMP00000115512; OTTHUMP00000200387
Orthologs: Mus musculus : Odc1 (ornithine decarboxylase, structural 1)  MGI
Rattus norvegicus : Odc1 (ornithine decarboxylase 1)
Related Pseudogenes: ODCP  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1210,551,749 - 10,559,553-NCBI
Human Genome Assembly HuRef210,432,740 - 10,440,685-NCBI
Human Genome Assembly GRCh37210,580,508 - 10,588,453-NCBI
Human Genome Assembly Build 36210,497,959 - 10,505,904-NCBI
Human Cytogenetic Map2p25 NCBI
Human Genome Assembly210,531,105 - 10,539,051 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on ODC1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 731324
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE