MCL1 (myeloid cell leukemia sequence 1 (BCL2-related))

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Keyword

Gene: MCL1 (myeloid cell leukemia sequence 1 (BCL2-related)) Homo sapiens

Symbol:

MCL1

Name:

myeloid cell leukemia sequence 1 (BCL2-related)

Description:

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; bcl2-L-3; bcl2-L-3; BCL2L3; EAT; induced myeloid leukemia cell differentiation protein Mcl-1; Mcl-1; MCL1-ES; mcl1/EAT; mcl1/EAT; MCL1L; MCL1S; MGC104264; MGC1839; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1, isoform 1; OTTHUMP00000032794; OTTHUMP00000032795; TM

Orthologs:

Mus musculus : Mcl1 (myeloid cell leukemia sequence 1) MGI
Rattus norvegicus : Mcl1 (myeloid cell leukemia sequence 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	1	157,048,430 - 157,053,622	-	NCBI
Human Genome Assembly HuRef	1	121,925,157 - 121,930,349	-	NCBI
Human Genome Assembly GRCh37	1	150,547,027 - 150,552,214	-	NCBI
Human Genome Assembly Build 36	1	148,813,658 - 148,818,760	-	NCBI
Human Cytogenetic Map	1	q21		NCBI
Human Genome Assembly	1	147,360,106 - 147,365,209		NCBI