NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha)

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Keyword

Gene: NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) Homo sapiens

Symbol:

NFKBIA

Name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Description:

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

I-kappa-B-alpha; IkappaBalpha; ikB-alpha; IKBA; MAD-3; major histocompatibility complex enhancer-binding protein MAD3; NF-kappa-B inhibitor alpha; NFKBI; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in b-cells inhibitor, alpha; OTTHUMP00000178842; OTTHUMP00000245015; OTTHUMP00000245885

Orthologs:

Mus musculus : Nfkbia (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha) MGI
Rattus norvegicus : Nfkbia (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	14	16,868,411 - 16,871,655	-	NCBI
Human Genome Assembly HuRef	14	15,984,422 - 15,987,685	-	NCBI
Human Genome Assembly GRCh37	14	35,870,716 - 35,873,960	-	NCBI
Human Genome Assembly Build 36	14	34,940,468 - 34,943,695	-	NCBI
Human Cytogenetic Map	14	q13		NCBI
Human Genome Assembly	14	34,940,467 - 34,943,695		NCBI