Gene: OGT (O-linked N-acetylglucosamine (GlcNAc) transferase)  Homo sapiens
Symbol: OGT
Name: O-linked N-acetylglucosamine (GlcNAc) transferase
Description: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ23071; HRNT1; MGC22921; o linked n-acetylglucosamine transferase; O-GLCNAC; O-GlcNAc transferase p110 subunit; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); O-linked N-acetylglucosamine transferase 110 kDa subunit; OTTHUMP00000032154; OTTHUMP00000032166; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase; uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
Orthologs: Mus musculus : Ogt (O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase))  MGI
Rattus norvegicus : Ogt (O-linked N-acetylglucosamine (GlcNAc) transferase)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1X70,759,415 - 70,802,250+NCBI
Human Genome Assembly HuRefX64,568,037 - 64,610,949+NCBI
Human Genome Assembly GRCh37X70,752,912 - 70,795,747+NCBI
Human Genome Assembly Build 36X70,669,658 - 70,712,465+NCBI
Human Cytogenetic MapXq13 NCBI
Human Genome AssemblyX70,535,953 - 70,578,761 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)

Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
  
More on OGT
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736466
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-05-28
Status: ACTIVE



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