RELA (RELA proto-oncogene, NF-kB subunit) - Rat Genome Database

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Gene: RELA (RELA proto-oncogene, NF-kB subunit) Homo sapiens
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Symbol: RELA
Name: RELA proto-oncogene, NF-kB subunit
RGD ID: 1352761
HGNC Page HGNC:9955
Description: Enables several functions, including DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and enzyme binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of DNA-templated transcription; and regulation of signal transduction. Acts upstream of or within nucleotide-binding activity oligomerization domain containing 2 signaling pathway. Located in NF-kappaB complex and cytosol. Part of NF-kappaB p50/p65 complex; chromatin; and transcription regulator complex. Is active in glutamatergic synapse and nucleus. Implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Biomarker of several diseases, including carcinoma (multiple); cervix uteri carcinoma in situ; middle ear disease (multiple); obstructive sleep apnea; and prostate disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AIF3BL3; CMCU; MGC131774; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NFKB3; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)); v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC100422456  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,653,601 - 65,663,857 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,653,599 - 65,663,090 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,421,072 - 65,430,387 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,178,393 - 65,186,951 (-)NCBINCBI36Build 36hg18NCBI36
Build 341165,178,392 - 65,186,951NCBI
Celera1162,747,772 - 62,757,128 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,748,056 - 61,757,436 (-)NCBIHuRef
CHM1_11165,305,002 - 65,314,374 (-)NCBICHM1_1
T2T-CHM13v2.01165,647,771 - 65,658,027 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute necrotizing pancreatitis  (ISO)
adenocarcinoma  (EXP)
Aicardi-Goutieres Syndrome 3  (IAGP)
alcoholic liver cirrhosis  (EXP)
amphetamine abuse  (EXP)
anaplastic large cell lymphoma  (EXP)
arteriosclerosis  (ISO)
Autoinflammatory Disease, Familial, Behcet-Like-3  (IAGP)
Bardet-Biedl syndrome  (IAGP)
Barrett's esophagus  (EXP)
Brain Injuries  (ISO)
brain ischemia  (EXP)
Brain Neoplasms  (EXP)
Breast Neoplasms  (EXP,IEP,IMP)
Cardiomegaly  (ISO)
Cerebral Hemorrhage  (ISO)
cervix uteri carcinoma in situ  (IEP)
Childhood Schizophrenia  (IAGP)
cholestasis  (EXP)
cholesteatoma of middle ear  (IEP)
Chronic Intermittent Hypoxia  (ISO)
chronic obstructive pulmonary disease  (ISO)
colitis  (EXP,ISO)
Colonic Neoplasms  (EXP)
Crohn's disease  (EXP)
cryptorchidism  (ISO)
cystitis  (EXP)
diabetic angiopathy  (EXP)
Diabetic Nephropathies  (EXP)
Disease Progression  (EXP)
Drug Eruptions  (EXP)
Drug-Induced Dyskinesia  (ISO)
ductal carcinoma in situ  (IAGP)
encephalitis  (ISO)
end stage renal disease  (EXP,ISO)
epilepsy  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (EXP,ISO)
Experimental Liver Cirrhosis  (EXP)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (EXP)
extrahepatic cholestasis  (EXP)
genetic disease  (IAGP)
glycogen storage disease V  (IAGP)
Heat Stroke  (EXP)
Hemorrhagic Shock  (IEP,ISO)
Hepatic Insufficiency  (EXP)
Hepatomegaly  (EXP)
high grade glioma  (IAGP)
hypertension  (EXP,ISO)
Insulin Resistance  (ISO)
intellectual disability  (IAGP)
Intestinal Reperfusion Injury  (ISO)
laryngeal squamous cell carcinoma  (IEP)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
lung non-small cell carcinoma  (IMP)
Lymphatic Metastasis  (IEP)
lymphoma  (IAGP)
mastoiditis  (IEP)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Invasiveness  (EXP)
Neoplastic Cell Transformation  (EXP)
neuroblastoma  (EXP)
obesity  (IEP)
obstructive sleep apnea  (IEP)
oral squamous cell carcinoma  (IEP)
otitis media  (IEP)
Ovarian Neoplasms  (IEP)
pancreatic cancer  (IEP)
pancreatic ductal carcinoma  (EXP)
Parkinsonism  (ISO)
Pneumococcal Meningitis  (ISO)
primary biliary cholangitis  (EXP)
prostate adenocarcinoma  (IEP,ISO)
prostate carcinoma in situ  (IEP,ISO)
prostatic hypertrophy  (IEP)
Prostatic Neoplasms  (IEP)
pulmonary hypertension  (ISO)
Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations  (IAGP)
renal cell carcinoma  (EXP,IEP,IMP)
renovascular hypertension  (ISO)
Reperfusion Injury  (EXP,ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (EXP)
Skin Neoplasms  (EXP)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
steatotic liver disease  (ISO)
Stomach Neoplasms  (EXP)
Subarachnoid Hemorrhage  (EXP)
Transplant Rejection  (ISO)
traumatic brain injury  (EXP)
type 2 diabetes mellitus  (EXP)
ulcerative colitis  (EXP)
ureteral obstruction  (EXP)
urinary bladder cancer  (IEP,ISO)
Uterine Cervical Neoplasms  (IEP)
uveitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (EXP,ISO)
(+)-catechin  (EXP,ISO)
(+)-epicatechin-3-O-gallate  (EXP)
(+)-Erythraline  (ISO)
(+)-isoborneol  (ISO)
(+)-pilocarpine  (ISO)
(+)-Pimaric acid  (EXP)
(+)-schisandrin B  (ISO)
(+)-Tetrandrine  (EXP,ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-hinokiresinol  (ISO)
(-)-matairesinol  (ISO)
(-)-selegiline  (EXP)
(20S)-ginsenoside Rg3  (ISO)
(20S)-ginsenoside Rh2  (EXP)
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (ISO)
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid  (ISO)
(5Z,8Z,11Z,13E)-15-HETE  (EXP)
(9R)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione  (ISO)
(E)-roxithromycin  (ISO)
(R)-adrenaline  (ISO)
(R)-carnitine  (ISO)
(R)-linalyl acetate  (ISO)
(R)-lipoic acid  (ISO)
(R)-noradrenaline  (EXP)
(R,R,R)-alpha-tocopherol  (EXP,ISO)
(S)-(-)-perillyl alcohol  (ISO)
(S)-colchicine  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
(Z)-ligustilide  (ISO)
1'-acetoxychavicol acetate  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,2-naphthoquinone  (ISO)
1,4-dithiothreitol  (EXP,ISO)
1,4-phenylenediamine  (EXP)
1,8-cineole  (EXP)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (ISO)
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine  (ISO)
1-bromopropane  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-hydroxy-2-naphthoic acid  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-nitropyrene  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP,ISO)
17-hydroxyjolkinolide B  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
2''-galloylhyperin  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2,2-tetramine  (ISO)
2,2,2-trichloroethanol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-D  (ISO)
2,4-dinitrotoluene  (ISO)
2,5-dihydroxybenzoic acid  (ISO)
2,5-hexanedione  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-acetyloxy-4-(trifluoromethyl)benzoic acid  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-aminopurine  (ISO)
2-arachidonoylglycerol  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (EXP)
2-hydroxyethyl methacrylate  (EXP)
2-methoxy-17beta-estradiol  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5'-triiodo-L-thyronine  (ISO)
3,3',5'-triiodothyronine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3,3'-diindolylmethane  (EXP)
3,4-dihydroxybenzoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
3-aminobenzamide  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methyladenine  (EXP,ISO)
3-methylcatechol  (ISO)
3-nitropropanoic acid  (ISO)
3-phenylprop-2-enal  (EXP,ISO)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside  (ISO)
4-amino-1,8-naphthalimide  (EXP)
4-hydroxy-17beta-estradiol  (EXP)
4-hydroxy-TEMPO  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (ISO)
4-methylcatechol  (ISO)
4-nitroquinoline N-oxide  (ISO)
4-phenylbutyric acid  (EXP,ISO)
5,6,7-trimethoxyflavone  (ISO)
5-aminoimidazole-4-carboxamide  (ISO)
5-aminolevulinic acid  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (EXP)
5-fluorouracil  (EXP,ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-methoxypsoralen  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP,ISO)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (ISO)
7,8-diacetoxy-4-methylcoumarin  (EXP)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
7-ketocholesterol  (EXP,ISO)
7H-xanthine  (ISO)
9-cis,11-trans-octadecadienoic acid  (ISO)
9H-xanthine  (ISO)
[6]-Shogaol  (EXP,ISO)
acenaphthoquinone  (EXP)
acetaldehyde  (EXP,ISO)
acetic acid  (ISO)
acetylsalicylic acid  (EXP,ISO)
Aciculatin  (ISO)
aconitine  (ISO)
acrolein  (EXP,ISO)
acrylamide  (EXP,ISO)
acrylic acid  (ISO)
acrylonitrile  (ISO)
acteoside  (EXP)
actinomycin D  (EXP)
adenine  (ISO)
adenosine  (EXP)
afatinib  (EXP)
aflatoxin B1  (ISO)
Aflatoxin G1  (ISO)
agmatine  (ISO)
agomelatine  (ISO)
agrimoniin  (EXP)
AH23848  (EXP)
AICA ribonucleotide  (ISO)
alachlor  (ISO)
alantolactone  (EXP)
alcohol  (ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
aldehydo-D-ribose  (ISO)
aldosterone  (ISO)
Alisol B  (ISO)
Alkannin  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
allicin  (EXP)
allopurinol  (EXP,ISO)
alloxan  (EXP,ISO)
alloxanthine  (EXP)
allyl alcohol  (ISO)
alpha-D-galactose  (EXP,ISO)
alpha-methylhistamine  (ISO)
alpha-naphthoflavone  (EXP,ISO)
alpinumisoflavone  (EXP)
alternariol  (EXP)
Altertoxin II  (EXP)
aluminium atom  (ISO)
aluminium sulfate (anhydrous)  (EXP)
aluminium(0)  (ISO)
amidotrizoic acid  (EXP)
amifostine  (EXP)
amiloride  (EXP,ISO)
aminoguanidine  (ISO)
amlexanox  (ISO)
ammonia  (ISO)
ammonium chloride  (ISO)
Ammothamnine  (EXP,ISO)
ampicillin  (ISO)
andrographolide  (EXP)
Anemoside B4  (ISO)
anethole  (EXP,ISO)
Anetholtrithion  (EXP)
aniline  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimycin A  (EXP,ISO)
antirheumatic drug  (EXP)
Antrocin  (EXP)
antroquinonol  (EXP)
apigenin  (EXP,ISO)
apocynin  (EXP,ISO)
apremilast  (ISO)
arachidonyl-2'-chloroethylamide  (ISO)
aristolochic acid A  (EXP,ISO)
arjunolic acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
asarone  (ISO)
asbestos  (ISO)
asiatic acid  (ISO)
aspalathin  (EXP)
asperuloside  (ISO)
astaxanthin  (EXP)
astilbin  (EXP)
astragaloside IV  (EXP,ISO)
atorvastatin calcium  (ISO)
ATP  (EXP,ISO)
Atractylodin  (EXP,ISO)
atrazine  (ISO)
atropine  (ISO)
aucubin  (ISO)
auranofin  (EXP)
aurantio-obtusin  (ISO)
aureusidin  (ISO)
azadirachtin A  (EXP)
aziridines  (ISO)
B 581  (EXP)
bafilomycin A1  (ISO)
baicalein  (EXP,ISO)
baicalin  (ISO)
Bardoxolone methyl  (EXP)
bazedoxifene  (ISO)
belinostat  (EXP)
benazepril  (ISO)
benfotiamine  (ISO)
benomyl  (ISO)
benzamide  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
Benzo[ghi]perylene  (EXP)
Berbamine  (EXP)
berberine  (EXP,ISO)
Bergenin  (EXP,ISO)
beta-carotene  (EXP)
beta-D-glucosamine  (EXP,ISO)
beta-D-glucosamine 6-sulfate  (EXP)
beta-Elemonic acid  (EXP)
beta-hexachlorocyclohexane  (ISO)
beta-ionone  (ISO)
beta-naphthoflavone  (ISO)
betulin  (ISO)
betulinic acid  (ISO)
bezafibrate  (ISO)
bifenthrin  (EXP,ISO)
bilirubin IXalpha  (EXP)
biochanin A  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (ISO)
boldenone  (ISO)
boric acid  (ISO)
bortezomib  (EXP)
bosentan  (EXP,ISO)
brazilein  (EXP)
brazilin  (EXP)
budesonide  (ISO)
bufalin  (EXP)
buspirone  (ISO)
butan-1-ol  (EXP)
butein  (EXP)
butyric acid  (ISO)
C.I. Natural Red 20  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcidiol  (EXP)
Calcimycin  (EXP)
calciol  (ISO)
calcitriol  (EXP,ISO)
calcium silicate  (EXP)
Calphostin C  (EXP)
calycosin  (ISO)
calyculin a  (EXP)
camptothecin  (EXP,ISO)
candesartan  (ISO)
cannabidiol  (EXP,ISO)
capsaicin  (EXP,ISO)
captan  (ISO)
captopril  (EXP)
carbamazepine  (EXP)
carbaryl  (ISO)
carbendazim  (ISO)
CARBENOXOLONE  (ISO)
carbidopa  (EXP,ISO)
carbon atom  (EXP)
carbon monoxide  (EXP)
carbon nanotube  (EXP,ISO)
carboplatin  (EXP)
carfilzomib  (ISO)
carmustine  (EXP,ISO)
carnosic acid  (EXP,ISO)
carnosine  (ISO)
Carnosol  (EXP)
carrageenan  (EXP,ISO)
carvacrol  (EXP)
carvedilol  (ISO)
casticin  (ISO)
Casuarictin  (EXP)
catechol  (ISO)
CCCP  (ISO)
cefaloridine  (ISO)
cefoxitin  (ISO)
celastrol  (EXP,ISO)
celecoxib  (EXP,ISO)
ceritinib  (EXP)
cerium trichloride  (ISO)
ceruletide  (ISO)
cetrorelix  (EXP)
cetylpyridinium  (EXP)
CGP 52608  (EXP)
chaetoglobosin A  (ISO)
chalcone  (ISO)
chalcones  (ISO)
chelerythrine  (EXP,ISO)
Chikusetsusaponin-IV  (EXP)
chitosan  (ISO)
chloroform  (EXP)
chlorogenic acid  (ISO)
chlorohydrocarbon  (ISO)
chloroquine  (EXP,ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP,ISO)
cholic acid  (ISO)
choline  (ISO)
chondroitin sulfate  (EXP)
chromium atom  (EXP,ISO)
chromium(6+)  (EXP,ISO)
chrysin  (EXP,ISO)
chrysin 5,7-dimethyl ether  (ISO)
ciglitazone  (EXP)
cilostazol  (EXP)
cimetidine  (EXP,ISO)
Cinobufagin  (EXP)
cirsilineol  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
citronellol  (ISO)
clenbuterol  (ISO)
clofibrate  (EXP,ISO)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (ISO)
coenzyme Q10  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP,ISO)
corosolic acid  (EXP)
cortisol  (EXP)
cortisone  (ISO)
corynoline  (ISO)
coumarins  (EXP)
crocidolite asbestos  (EXP,ISO)
crocin-1  (ISO)
crotonaldehyde  (ISO)
Cryptotanshinone  (EXP)
cudraflavone B  (EXP)
cudratricusxanthone A  (ISO)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
Curcumol  (EXP)
cyclizine  (ISO)
cycloheximide  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyhalothrin  (ISO)
cylindrospermopsin  (EXP)
cytarabine  (EXP)
D-glucose  (EXP,ISO)
D-ribofuranose  (ISO)
dabrafenib  (EXP)
daidzein  (ISO)
dapagliflozin  (ISO)
dapsone  (EXP)
DAPT  (ISO)
daunorubicin  (EXP)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
Decursin  (ISO)
deferiprone  (EXP)
deguelin  (EXP)
dehydroepiandrosterone  (ISO)
deoxycholic acid  (EXP)
Deoxycorticosterone acetate  (ISO)
deoxynivalenol  (EXP,ISO)
Deoxyschizandrin  (EXP)
desferrioxamine B  (ISO)
desloratadine  (EXP)
Destruxin B  (EXP)
dexamethasone  (EXP,ISO)
dexamethasone phosphate  (EXP)
dexmedetomidine  (ISO)
dextran sulfate  (ISO)
dextromethorphan  (ISO)
diallyl disulfide  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
diazepam  (EXP,ISO)
dibenziodolium  (EXP,ISO)
dibutyl phthalate  (ISO)
dibutylstannane  (ISO)
dichloroacetyl chloride  (ISO)
diclofenac  (EXP,ISO)
dicoumarol  (EXP)
dicrotophos  (EXP)
dieckol  (EXP)
diethyl maleate  (EXP)
diethyl phthalate  (ISO)
diethyldithiocarbamic acid  (ISO)
diethylstilbestrol  (EXP)
dihydroartemisinin  (EXP)
dihydrogen  (ISO)
diiodine  (ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (EXP,ISO)
diltiazem  (EXP)
dimemorfan  (ISO)
dimethyl fumarate  (EXP)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (EXP)
diminazene diaceturate  (ISO)
Diosbulbin B  (ISO)
dioscin  (ISO)
diosgenin  (EXP,ISO)
diosmin  (ISO)
dioxygen  (EXP,ISO)
diprotium  (ISO)
diquat  (ISO)
disodium cromoglycate  (ISO)
disodium selenite  (EXP,ISO)
docebenone  (EXP)
dodecanoic acid  (EXP)
donepezil hydrochloride  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
ebselen  (EXP)
edaravone  (ISO)
elemental carbon  (EXP)
elemental selenium  (EXP,ISO)
ellagic acid  (EXP,ISO)
emamectin benzoate  (EXP)
embelin  (ISO)
emodin  (ISO)
enalapril  (ISO)
endosulfan  (ISO)
entinostat  (EXP,ISO)
enzyme inhibitor  (EXP)
ergosterol  (ISO)
ergothioneine  (ISO)
eriodictyol  (EXP)
erlotinib hydrochloride  (EXP)
esculetin  (EXP)
estriol  (EXP)
etacrynic acid  (EXP)
ethanol  (EXP,ISO)
ethidium  (ISO)
ethyl acetate  (EXP)
ethylene glycol  (ISO)
ethylisopropylamiloride  (EXP)
etoposide  (EXP)
eugenol  (EXP,ISO)
eupatilin  (ISO)
Evodiamine  (EXP)
excitatory amino acid agonist  (ISO)
famotidine  (ISO)
Fargesin  (ISO)
fasudil  (EXP,ISO)
febuxostat  (ISO)
felodipine  (ISO)
fenbendazole  (EXP)
fenofibrate  (EXP,ISO)
ferroheme b  (EXP,ISO)
ferruginol  (EXP)
ferulic acid  (EXP,ISO)
Fexofenadine hydrochloride  (EXP)
finasteride  (ISO)
fisetin  (EXP,ISO)
Flavokawain A  (ISO)
flavone  (ISO)
flubendazole  (EXP)
fluorescein 5-isothiocyanate  (ISO)
fluoxetine  (ISO)
flurbiprofen  (ISO)
fluticasone  (EXP)
fluvastatin  (EXP)
folic acid  (EXP,ISO)
folpet  (ISO)
formaldehyde  (EXP,ISO)
fosinopril  (ISO)
Fraxinellone  (EXP)
fructose  (ISO)
fucoidan  (EXP)
fucoxanthin  (ISO)
fulvestrant  (EXP,ISO)
Fulvic acid  (EXP)
fumaric acid  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
Fusaric acid  (EXP)
gadodiamide hydrate  (EXP)
gadolinium atom  (EXP)
gadolinium trichloride  (EXP,ISO)
galactose  (EXP,ISO)
galangin  (EXP,ISO)
galanthamine  (ISO)
gallic acid  (EXP,ISO)
gallocatechin  (EXP)
gamma-hexachlorocyclohexane  (ISO)
Ganoderic acid A  (ISO)
Garcinol  (EXP)
gastrin-17  (EXP)
Gastrodin  (ISO)
gefitinib  (EXP)
geldanamycin  (EXP)
gemcitabine  (EXP,ISO)
genistein  (EXP,ISO)
gentamycin  (EXP,ISO)
Geraniin  (EXP,ISO)
geraniol  (ISO)
gingerol  (EXP,ISO)
Ginkgolide A  (ISO)
Ginkgolide C  (ISO)
ginsenoside C-K  (ISO)
ginsenoside F1  (EXP)
ginsenoside Rb1  (ISO)
ginsenoside Re  (ISO)
gliclazide  (ISO)
gliotoxin  (EXP)
glucose  (EXP,ISO)
glutathione  (EXP,ISO)
glutathione disulfide  (ISO)
glyburide  (ISO)
glycine betaine  (ISO)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
glycyrrhizinic acid  (EXP,ISO)
glyphosate  (EXP,ISO)
Goe 6976  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
graphite  (EXP)
guggulsterone  (EXP,ISO)
GW 501516  (ISO)
GW 6471  (EXP)
gypenoside LXXV  (ISO)
haloperidol  (ISO)
harmaline  (EXP)
Harpagide  (ISO)
helenalin  (EXP,ISO)
heme b  (EXP,ISO)
hemin  (ISO)
heparin  (EXP)
hesperetin  (ISO)
hesperidin  (ISO)
hexachlorobenzene  (ISO)
hexadecanoic acid  (EXP,ISO)
high-density lipoprotein cholesterol  (EXP)
hinokiflavone  (ISO)
histamine  (EXP)
homocysteine  (EXP,ISO)
homoeriodictyol  (ISO)
Honokiol  (EXP,ISO)
huperzine A  (ISO)
hyaluronic acid  (EXP,ISO)
hydralazine  (EXP)
hydrogen chloride  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP,ISO)
hydroxychloroquine  (EXP)
hydroxysafflor yellow A  (EXP)
hydroxytyrosol  (EXP)
hypoxanthine  (ISO)
ibrutinib  (EXP)
ibuprofen  (EXP,ISO)
icariin  (EXP,ISO)
idelalisib  (EXP)
imidacloprid  (ISO)
immunological adjuvant  (ISO)
indirubin-3'-monoxime  (ISO)
indole-3-acetic acid  (EXP)
indole-3-methanol  (EXP,ISO)
indometacin  (EXP,ISO)
indoprofen  (ISO)
inulin  (ISO)
inuviscolide  (EXP)
iohexol  (EXP)
iomeprol  (EXP)
iopamidol  (EXP)
irbesartan  (ISO)
irinotecan  (EXP,ISO)
iron atom  (EXP,ISO)
iron dextran  (EXP,ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP,ISO)
iron(III) nitrilotriacetate  (ISO)
Isoangustone A  (EXP)
isoeugenol  (EXP,ISO)
isoflavones  (EXP)
isoflurane  (ISO)
Isoliensinine  (EXP,ISO)
isoliquiritigenin  (EXP,ISO)
isoprenaline  (ISO)
isorhamnetin  (ISO)
isothiocyanate  (ISO)
isotretinoin  (ISO)
isovitexin  (ISO)
ivermectin  (EXP)
jaceosidin  (EXP)
JBIR-99  (EXP)
JTE-013  (EXP)
kaempferol  (EXP,ISO)
kaempferol 3-O-beta-D-glucoside  (ISO)
kainic acid  (ISO)
ketamine  (ISO)
ketoconazole  (ISO)
KN-93  (ISO)
KT 5823  (EXP)
Kukoamine B  (ISO)
kuwanone G  (ISO)
kynurenic acid  (ISO)
L-1,4-dithiothreitol  (EXP,ISO)
L-365260  (ISO)
L-arginine  (ISO)
L-ascorbic acid  (EXP,ISO)
L-cysteine  (ISO)
L-gamma-glutamyl-L-cysteine  (ISO)
L-methionine  (ISO)
L-proline betaine  (EXP)
L-selenocysteine  (EXP)
lactacystin  (EXP)
lactulose  (ISO)
lansoprazole  (ISO)
lapatinib  (EXP)
lead diacetate  (ISO)
lead nitrate  (EXP,ISO)
lead(0)  (EXP,ISO)
lentinan  (ISO)
Leonurine  (ISO)
leptomycin B  (EXP)
letrozole  (ISO)
levamisole  (EXP)
levofloxacin  (ISO)
Licochalcone B  (ISO)
licoricidin  (EXP)
limonene  (ISO)
linagliptin  (ISO)
linalyl acetate  (ISO)
linsidomine  (ISO)
linuron  (ISO)
lipoic acid  (ISO)
lipophosphoglycan  (EXP)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (ISO)
lipoxin A4  (EXP,ISO)
liquiritigenin  (ISO)
liquiritin  (ISO)
liraglutide  (ISO)
lithium atom  (EXP,ISO)
lithium carbonate  (ISO)
lithium chloride  (EXP,ISO)
lithium hydride  (EXP,ISO)
lithocholic acid  (EXP)
loganin  (ISO)
lonafarnib  (EXP)
losartan  (ISO)
Lucidone  (EXP)
lupeol  (EXP)
lutein  (EXP)
luteolin  (EXP,ISO)
luzindole  (EXP)
LY294002  (EXP,ISO)
lycopene  (ISO)
Macrosphelide B  (ISO)
Magnolol  (EXP)
malaoxon  (EXP)
malathion  (EXP,ISO)
Malonoben  (EXP)
malvidin  (ISO)
mancozeb  (EXP)
maneb  (ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
mangiferin  (EXP,ISO)
masoprocol  (EXP)
Mecamylamine  (ISO)
medroxyprogesterone acetate  (EXP)
melamine  (EXP)
Melarsoprol  (EXP)
melatonin  (EXP,ISO)
melittin  (EXP,ISO)
menadione  (EXP)
mercaptoethanol  (EXP)
mercaptopurine  (EXP)
mercury atom  (EXP,ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP,ISO)
mesalamine  (ISO)
metformin  (EXP,ISO)
methamphetamine  (EXP,ISO)
methoctramine tetrahydrochloride  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methyl beta-cyclodextrin  (EXP)
Methyl palmitate  (ISO)
methylarsonic acid  (EXP)
methylglyoxal  (ISO)
methylisothiazolinone  (EXP)
methyllycaconitine  (ISO)
methylmercury chloride  (EXP,ISO)
Methylthiouracil  (EXP)
metronidazole  (ISO)
mevalonic acid  (EXP,ISO)
mevinphos  (ISO)
microcystin-LR  (ISO)
mifepristone  (EXP,ISO)
minocycline  (ISO)
miquelianin  (EXP)
mirabegron  (ISO)
mirtazapine  (ISO)
mitomycin C  (EXP)
MK-2206  (EXP)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
Monobutylphthalate  (EXP,ISO)
monocrotaline  (ISO)
monosodium L-glutamate  (ISO)
monotropein  (ISO)
montelukast  (ISO)
morin  (ISO)
morphine  (EXP,ISO)
Morroniside  (EXP,ISO)
morusin  (EXP,ISO)
moxifloxacin  (EXP)
muramyl dipeptide  (EXP)
mycophenolic acid  (EXP,ISO)
myo-inositol hexakisphosphate  (EXP,ISO)
myricetin  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP,ISO)
N,N-dimethylsphingosine  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP,ISO)
N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide  (ISO)
N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
N-phenylthiourea  (EXP)
N-tosyl-L-phenylalanyl chloromethyl ketone  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naproxen  (EXP)
Narciclasine  (ISO)
naringin  (EXP,ISO)
neoastilbin  (EXP)
neoechinulin A  (ISO)
neomycin  (ISO)
neratinib  (EXP)
nerolidol  (ISO)
neurotensin  (EXP)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (ISO)
nickel sulfate  (EXP,ISO)
niclosamide  (EXP,ISO)
nicotinamide  (EXP,ISO)
nicotine  (EXP,ISO)
nicotinic acid  (EXP,ISO)
nifedipine  (ISO)
nifuroxazide  (ISO)
nilotinib  (ISO)
nimesulide  (ISO)
nitric oxide  (ISO)
nitroflurbiprofen  (ISO)
nitroglycerin  (ISO)
nitroprusside  (EXP,ISO)
nocodazole  (ISO)
Nodularin  (EXP)
nonane  (ISO)
nonivamide  (EXP)
Nonylphenol  (EXP,ISO)
NORCANTHARIDIN  (ISO)
notoginsenoside R1  (ISO)
nystatin  (ISO)
O-(chloroacetylcarbamoyl)fumagillol  (ISO)
O-acetyl-L-carnitine  (ISO)
o-anisidine  (EXP)
Obacunone  (EXP)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
okadaic acid  (EXP,ISO)
oleanolic acid  (EXP)
oleuropein  (EXP)
oligopeptide  (ISO)
Olmesartan medoxomil  (ISO)
omacetaxine mepesuccinate  (EXP)
omeprazole  (EXP,ISO)
organoselenium compound  (ISO)
orlistat  (ISO)
oroxylin A  (ISO)
ospemifene  (ISO)
osthole  (EXP,ISO)
oxaliplatin  (ISO)
oxidopamine  (EXP,ISO)
oxybenzone  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (EXP)
p-tolualdehyde  (ISO)
Pachymic acid  (EXP,ISO)
paclitaxel  (EXP,ISO)
Paeonol  (ISO)
panobinostat  (EXP)
paracetamol  (ISO)
paraquat  (EXP,ISO)
paricalcitol  (EXP)
parthenolide  (EXP,ISO)
patchouli alcohol  (EXP,ISO)
pelargonidin  (EXP,ISO)
pentachlorophenol  (EXP)
Pentoxifylline  (EXP,ISO)
peptidoglycan  (EXP)
perfluorodecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
pergolide  (EXP)
perillyl alcohol  (ISO)
perindopril  (ISO)
permethrin  (ISO)
peroxynitrous acid  (EXP)
pevonedistat  (EXP)
phenethyl caffeate  (EXP,ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (EXP)
phenylarsine oxide  (EXP)
phenylbutazone  (EXP)
phenylephrine  (ISO)
phenylpropanolamine  (ISO)
phenytoin  (EXP,ISO)
PhIP  (ISO)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosalone  (ISO)
phosphorus atom  (EXP)
phosphorus(.)  (EXP)
Phytolaccoside E  (EXP)
piclamilast  (ISO)
pifithrin-?  (ISO)
pinitol  (ISO)
pioglitazone  (ISO)
piperine  (EXP,ISO)
pipoxolan  (ISO)
Pirarubicin  (ISO)
pirfenidone  (ISO)
pirinixic acid  (ISO)
platycodin D  (EXP,ISO)
poly(I:C)  (EXP)
polyphosphates  (EXP)
Potassium 2,6-dihydroxytriazinecarboxylate  (ISO)
potassium bromate  (ISO)
potassium dichromate  (EXP,ISO)
prilocaine  (EXP)
proanthocyanidin  (ISO)
procyanidin B3  (ISO)
prodigiosin  (ISO)
progesterone  (EXP,ISO)
propanil  (ISO)
prostaglandin E1  (ISO)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (ISO)
protein kinase inhibitor  (EXP,ISO)
pterostilbene  (EXP,ISO)
puerarin  (EXP,ISO)
Punicalagin  (ISO)
purine-6-thiol  (EXP)
pyrrolidine dithiocarbamate  (EXP,ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quercitrin  (ISO)
quinazolines  (EXP)
raloxifene  (EXP,ISO)
ranitidine  (ISO)
rasagiline  (EXP)
rebaudioside A  (ISO)
regorafenib  (EXP)
resiquimod  (EXP)
resolvin D1  (ISO)
resolvin D2  (ISO)
resveratrol  (EXP,ISO)
Rhein  (EXP,ISO)
Rhynchophylline  (ISO)
rimonabant  (ISO)
ritonavir  (EXP)
rivaroxaban  (ISO)
rivastigmine  (ISO)
rocaglamide  (EXP)
roflumilast  (EXP,ISO)
romidepsin  (EXP)
rosmarinic acid  (ISO)
rotenone  (EXP,ISO)
royal jelly  (ISO)
rubimaillin  (EXP)
Ruscogenin  (ISO)
rutin  (EXP,ISO)
ruxolitinib  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
S-allylcysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
S-nitrosoglutathione  (EXP)
salicylates  (ISO)
salicylic acid  (ISO)
Salidroside  (ISO)
Salinomycin  (EXP)
Salmeterol xinafoate  (EXP)
salsalate  (ISO)
sappanchalcone  (EXP)
sarpogrelate  (EXP,ISO)
saxagliptin  (ISO)
SB 203580  (EXP,ISO)
SB 290157  (ISO)
SCH 23390  (ISO)
SCH772984  (EXP)
scoparone  (EXP,ISO)
scopolamine  (ISO)
SDZ PSC 833  (EXP)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenic acid  (EXP)
selenium atom  (EXP,ISO)
selenomethionine  (EXP)
serotonin  (EXP)
serpentine asbestos  (EXP)
sesquiterpene  (EXP)
sevoflurane  (ISO)
shikimic acid  (EXP)
Shikonin  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP,ISO)
sinapic acid  (ISO)
sinigrin  (ISO)
sirolimus  (EXP,ISO)
sirtinol  (EXP,ISO)
SM-164  (EXP)
sodium acetate trihydrate  (ISO)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
sodium chloride  (EXP)
sodium chromate  (ISO)
sodium disulfite  (ISO)
sodium fluoride  (EXP,ISO)
sodium hydrogencarbonate  (ISO)
Sodium oleate  (EXP)
sodium propionate  (ISO)
Sodium salicylate  (EXP,ISO)
solasodine  (EXP)
Soman  (ISO)
Sophoricoside  (ISO)
sorafenib  (ISO)
sorbinil  (ISO)
soyasaponin I  (ISO)
sphingosine 1-phosphate  (EXP)
splitomicin  (EXP)
squalene  (ISO)
staurosporine  (EXP,ISO)
streptozocin  (EXP,ISO)
succinic acid  (EXP)
sucrose  (ISO)
sulfasalazine  (EXP,ISO)
sulfates  (EXP)
sulforaphane  (EXP,ISO)
sulfur dioxide  (ISO)
sulindac  (EXP)
sulindac sulfide  (EXP)
sulindac sulfone  (EXP)
sumatriptan  (ISO)
surfactin  (EXP)
surfactin C  (EXP)
synephrine  (ISO)
syringic acid  (EXP)
syringin  (ISO)
T-2 toxin  (EXP,ISO)
tacrolimus hydrate  (ISO)
tadalafil  (ISO)
tamibarotene  (EXP)
tamoxifen  (EXP)
tangeretin  (ISO)
Tanshinone I  (EXP)
taurine  (ISO)
taurocholic acid  (EXP,ISO)
telmisartan  (EXP,ISO)
temozolomide  (EXP)
tenofovir disoproxil fumarate  (ISO)
teprenone  (EXP,ISO)
terameprocol  (ISO)
teriflunomide  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloro-1,4-benzoquinone  (ISO)
tetrachloromethane  (ISO)
tetramethylpyrazine  (EXP,ISO)
Tetramethylthiourea  (EXP)
tetraphene  (EXP)
thalidomide  (EXP,ISO)
thapsigargin  (ISO)
Theaflavin 3,3'-digallate  (ISO)
theophylline  (EXP)
thioacetamide  (ISO)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
thymoquinone  (ISO)
Timosaponin b ii  (ISO)
Tiron  (EXP,ISO)
titanium atom  (ISO)
titanium dioxide  (EXP,ISO)
toluene 2,4-diisocyanate  (ISO)
tomatidine  (EXP)
tranilast  (ISO)
trans-anethole  (EXP,ISO)
trans-caffeic acid  (ISO)
trans-chalcone  (ISO)
trans-isoeugenol  (EXP,ISO)
trans-piceid  (EXP,ISO)
trelagliptin  (ISO)
tributylstannane  (EXP,ISO)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triciribine  (ISO)
triclosan  (EXP,ISO)
trilobatin  (ISO)
trimethyltin  (ISO)
Triptolide  (ISO)
tris(2-chloroethyl) phosphate  (EXP)
troglitazone  (EXP)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
Tropicamide  (ISO)
tropisetron  (EXP,ISO)
trovafloxacin  (EXP,ISO)
Tungsten carbide  (ISO)
tunicamycin  (EXP)
Tylophorine  (EXP)
umbelliferone  (ISO)
undecan-2-one  (ISO)
urethane  (ISO)
ursolic acid  (EXP)
vadimezan  (ISO)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vanadyl sulfate  (EXP)
vancomycin  (ISO)
vanillin  (ISO)
varenicline  (ISO)
venlafaxine hydrochloride  (ISO)
venom  (EXP)
verteporfin  (ISO)
vildagliptin  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
vitamin D  (ISO)
vitamin E  (EXP,ISO)
vitamin K  (ISO)
Voacamine  (EXP)
vorinostat  (EXP)
wedelolactone  (EXP,ISO)
withaferin A  (EXP)
wogonin  (EXP,ISO)
wortmannin  (ISO)
WR-1065  (EXP)
xanthohumol  (EXP)
Y-27632  (EXP,ISO)
Yangonin  (ISO)
yohimbine  (ISO)
zearalenone  (ISO)
zerumbone  (EXP)
zidovudine  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP)
zinc oxide  (EXP)
zinc protoporphyrin  (EXP,ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zingerone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acetaldehyde metabolic process  (IEA,ISO)
animal organ morphogenesis  (IEA,ISO)
antiviral innate immune response  (IDA)
canonical NF-kappaB signal transduction  (IBA,IDA,IEA,IGI,IMP)
cellular defense response  (NAS)
cellular response to angiotensin  (IMP)
cellular response to hepatocyte growth factor stimulus  (IEA,ISO)
cellular response to hydrogen peroxide  (IDA)
cellular response to interleukin-1  (IDA)
cellular response to interleukin-6  (IMP)
cellular response to lipopolysaccharide  (IBA,IEA,IMP,ISO)
cellular response to lipoteichoic acid  (IMP)
cellular response to nicotine  (IMP)
cellular response to peptidoglycan  (IMP)
cellular response to tumor necrosis factor  (IDA,IEA,IMP,ISO)
chromatin organization  (IEA)
cytokine-mediated signaling pathway  (IDA)
defense response  (IEA,ISO)
defense response to tumor cell  (IDA)
defense response to virus  (NAS)
DNA-templated transcription  (IEA)
hair follicle development  (IEA,ISO)
inflammatory response  (IBA,IDA,IEA)
innate immune response  (IBA,IEA)
interleukin-1-mediated signaling pathway  (IGI)
intracellular signal transduction  (IDA)
liver development  (IEA)
negative regulation of angiogenesis  (IMP)
negative regulation of apoptotic process  (IDA,IEA)
negative regulation of DNA-templated transcription  (IDA)
negative regulation of extrinsic apoptotic signaling pathway  (IEA,IMP,ISO)
negative regulation of insulin receptor signaling pathway  (IEA,ISO)
negative regulation of miRNA transcription  (IMP)
negative regulation of non-canonical NF-kappaB signal transduction  (IMP)
negative regulation of protein catabolic process  (IEA,ISO)
negative regulation of protein sumoylation  (IEA)
negative regulation of transcription by RNA polymerase II  (IDA,IEA)
neuropeptide signaling pathway  (IGI)
non-canonical NF-kappaB signal transduction  (IBA,IDA,IEA)
nucleotide-binding oligomerization domain containing 2 signaling pathway  (IDA)
positive regulation of amyloid-beta formation  (IEA,ISS)
positive regulation of canonical NF-kappaB signal transduction  (IEA,IEP)
positive regulation of cell population proliferation  (IDA,ISO)
positive regulation of chondrocyte differentiation  (ISO)
positive regulation of DNA-templated transcription  (IDA,IEA,IMP,ISO)
positive regulation of gene expression  (IMP)
positive regulation of interleukin-1 beta production  (IDA)
positive regulation of interleukin-12 production  (IEA,ISO)
positive regulation of interleukin-6 production  (IDA,IMP)
positive regulation of interleukin-8 production  (IDA,IGI)
positive regulation of leukocyte adhesion to vascular endothelial cell  (IMP)
positive regulation of miRNA metabolic process  (IMP)
positive regulation of miRNA transcription  (IGI,IMP)
positive regulation of non-canonical NF-kappaB signal transduction  (IMP)
positive regulation of Schwann cell differentiation  (IEA,ISO)
positive regulation of T cell receptor signaling pathway  (IMP)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IEA,IGI,IMP,ISS,NAS)
positive regulation of vascular endothelial growth factor production  (IMP)
postsynapse to nucleus signaling pathway  (IDA,IMP)
prolactin signaling pathway  (IMP)
protein catabolic process  (IEA,ISO)
regulation of DNA-templated transcription  (IEA,IMP)
regulation of gene expression  (IEA)
regulation of inflammatory response  (IEA,ISO,ISS)
regulation of transcription by RNA polymerase II  (IDA)
response to amino acid  (IEA,ISO)
response to bacterium  (IEA,ISO)
response to cAMP  (IEA,ISO)
response to cobalamin  (IEA,ISO)
response to cytokine  (IBA,IEA,ISO)
response to hydrogen peroxide  (IEA,ISO)
response to inorganic substance  (IEA,ISO)
response to insulin  (IEA,ISO)
response to interleukin-1  (IGI)
response to ischemia  (IEA,ISO)
response to lipopolysaccharide  (IEA,ISO)
response to mechanical stimulus  (IEA,ISO)
response to muramyl dipeptide  (IEA,ISO)
response to muscle stretch  (IEA,ISO)
response to organic cyclic compound  (IEA,ISO)
response to organic substance  (ISO)
response to progesterone  (IEA,ISO)
response to UV-B  (IDA)
response to xenobiotic stimulus  (IEA,ISO)
toll-like receptor 4 signaling pathway  (IDA)
tumor necrosis factor-mediated signaling pathway  (IDA,IGI,IMP)
vascular endothelial growth factor signaling pathway  (IMP)

Cellular Component
chromatin  (IC,IDA,IEA,IGI,ISA)
cytoplasm  (IBA,IDA,IEA,IGI,ISO)
cytosol  (IDA,IEA,TAS)
glutamatergic synapse  (IDA,IMP)
NF-kappaB complex  (IPI,NAS)
NF-kappaB p50/p65 complex  (IBA,IDA,IEA,NAS)
nucleolus  (IDA)
nucleoplasm  (TAS)
nucleus  (IBA,IDA,IEA,IGI,IMP,ISO)
protein-containing complex  (IEA,ISO)
synapse  (IEA,ISO)
transcription regulator complex  (IDA,IEA)

References

References - curated
# Reference Title Reference Citation
1. The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation. Abdulla D, etal., Drug Metab Dispos. 2005 Oct;33(10):1521-31. Epub 2005 Jul 8.
2. Bcl-xL expression and regulation in the progression, recurrence, and cisplatin resistance of oral cancer. Alam M and Mishra R, Life Sci. 2021 Sep 1;280:119705. doi: 10.1016/j.lfs.2021.119705. Epub 2021 Jun 8.
3. Effect of early insulin therapy on nuclear factor kappaB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats. Bi Y, etal., Acta Diabetol. 2008 May 24.
4. Activation of striatal inflammatory mediators and caspase-3 is central to haloperidol-induced orofacial dyskinesia. Bishnoi M, etal., Eur J Pharmacol. 2008 Jun 14.
5. Tetradecylthioacetic acid prevents the inflammatory response in two-kidney, one-clip hypertension. Bivol LM, etal., Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R438-47. Epub 2007 Nov 21.
6. Upregulation of nuclear factor-kappaB (NF-kappaB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer. Branca M, etal., Diagn Cytopathol. 2006 Aug;34(8):555-63.
7. The involvement of NF-kappaB p65/p52 in the effects of GDNF on DA neurons in early PD rats. Cao JP, etal., Brain Res Bull. 2008 Jul 30;76(5):505-11. Epub 2008 Apr 9.
8. Glutamine decreases intestinal nuclear factor kappa B activity and pro-inflammatory cytokine expression after traumatic brain injury in rats. Chen G, etal., Inflamm Res. 2008 Feb;57(2):57-64.
9. Cryptorchidism-induced CFTR down-regulation results in disruption of testicular tight junctions through up-regulation of NF-kappaB/COX-2/PGE2. Chen J, etal., Hum Reprod. 2012 Sep;27(9):2585-97. doi: 10.1093/humrep/des254. Epub 2012 Jul 9.
10. Celecoxib attenuates liver steatosis and inflammation in non-alcoholic steatohepatitis induced by high-fat diet in rats. Chen J, etal., Mol Med Report. 2011 Jun 2. doi: 10.3892/mmr.2011.501.
11. First evidence of aryl hydrocarbon receptor as a druggable target in hypertension induced by chronic intermittent hypoxia. Coelho NR, etal., Pharmacol Res. 2020 Sep;159:104869. doi: 10.1016/j.phrs.2020.104869. Epub 2020 May 19.
12. Postshock mesenteric lymph induces endothelial NF-kappaB activation. Damle SS, etal., J Surg Res. 2007 Nov;143(1):136-40. Epub 2007 Aug 20.
13. Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock. Deree J, etal., J Surg Res. 2007 Nov;143(1):99-108.
14. Hepatic transcription factor activation and proinflammatory mediator production is attenuated by hypertonic saline and pentoxifylline resuscitation after hemorrhagic shock. Deree J, etal., J Trauma. 2008 May;64(5):1230-8; discussion 1238-9.
15. Activation of nuclear factor-kappaB in human prostate carcinogenesis and association to biochemical relapse. Domingo-Domenech J, etal., Br J Cancer. 2005 Nov 28;93(11):1285-94.
16. Diabetes-induced atrophy is associated with a muscle-specific alteration in NF-kappaB activation and expression. Frier BC, etal., Cell Stress Chaperones. 2008 Jul 17.
17. Tamoxifen treatment for breast cancer enforces a distinct gene-expression profile on the human endometrium: an exploratory study. Gielen SC, etal., Endocr Relat Cancer. 2005 Dec;12(4):1037-49.
18. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
19. Renal NF-kappaB activation and TNF-alpha upregulation correlate with salt-sensitive hypertension in Dahl salt-sensitive rats. Gu JW, etal., Am J Physiol Regul Integr Comp Physiol. 2006 Dec;291(6):R1817-24. Epub 2006 Jul 13.
20. Inhibition of NF-kappaB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats. Gupta S, etal., Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H20-9. Epub 2005 Mar 4.
21. Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors. Gurova KV, etal., Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17448-53. Epub 2005 Nov 15.
22. Shared principles in NF-kappaB signaling. Hayden MS and Ghosh S, Cell. 2008 Feb 8;132(3):344-62.
23. Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-kappaB in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis. Huang C, etal., Oncol Rep. 2009 Jul;22(1):89-95.
24. Expression of Toll-Like Receptors 2, 4 and Nuclear Factor Kappa B in Mucosal Lesions of Human Otitis: Pattern and Relationship in a Clinical Immunohistochemical Study. Jesic S, etal., Ann Otol Rhinol Laryngol. 2014 Apr 1.
25. MG132 alleviates liver injury induced by intestinal ischemia/reperfusion in rats: involvement of the AhR and NFκB pathways. Jing H, etal., J Surg Res. 2012 Jul;176(1):63-73. doi: 10.1016/j.jss.2011.09.001. Epub 2011 Sep 29.
26. Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis. Kretzmann NA, etal., Inflamm Bowel Dis. 2008 Jul 11.
27. Nuclear localization of nuclear factor-kappaB p65 in primary prostate tumors is highly predictive of pelvic lymph node metastases. Lessard L, etal., Clin Cancer Res. 2006 Oct 1;12(19):5741-5.
28. Clinical significance of nuclear factor (NF)-kappaB levels in urothelial carcinoma of the urinary bladder. Levidou G, etal., Virchows Arch. 2008 Mar;452(3):295-304.
29. microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro. Li Q, etal., Cell Biol Toxicol. 2021 Jul 31. pii: 10.1007/s10565-021-09638-5. doi: 10.1007/s10565-021-09638-5.
30. Histone demethylase JARID1B regulates proliferation and migration of pulmonary arterial smooth muscle cells in mice with chronic hypoxia-induced pulmonary hypertension via nuclear factor-kappa B (NFkB). Li Y, etal., Cardiovasc Pathol. 2018 Nov-Dec;37:8-14. doi: 10.1016/j.carpath.2018.07.004. Epub 2018 Aug 3.
31. [Effects of Chaiqin Chengqi Decoction on activation of nuclear factor-kappaB in pancreas of rats with acute necrotizing pancreatitis] Li YH, etal., Zhong Xi Yi Jie He Xue Bao. 2008 Feb;6(2):180-4.
32. TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats. Lin ZP, etal., Mol Med Rep. 2020 Aug;22(2):651-660. doi: 10.3892/mmr.2020.11134. Epub 2020 May 7.
33. Analysis of nucleotide-binding oligomerization domain proteins in a murine model of pneumococcal meningitis. Liu X, etal., BMC Infect Dis. 2014 Dec 2;14(1):648.
34. MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory Pathways. Liu Z, etal., Oxid Med Cell Longev. 2019 Sep 10;2019:8948657. doi: 10.1155/2019/8948657. eCollection 2019.
35. Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation. Lubin FD, etal., J Neurochem. 2007 Nov;103(4):1381-95. Epub 2007 Aug 28.
36. Anti-inflammatory effect of angiotensin type 1 receptor antagonist on endotoxin-induced uveitis in rats. Miyazaki A, etal., Graefes Arch Clin Exp Ophthalmol. 2008 May;246(5):747-57. Epub 2007 Dec 18.
37. Activation of nuclear factor-kappa B is linked to resistance to neoadjuvant chemotherapy in breast cancer patients. Montagut C, etal., Endocr Relat Cancer. 2006 Jun;13(2):607-16.
38. Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model. Narayanan BA, etal., Clin Cancer Res. 2004 Nov 15;10(22):7727-37.
39. [NF-kappaB subunit p65/RelA expression in ovarian carcinoma: prognostic impact and link to COX-2 overexpression] Niesporek S, etal., Verh Dtsch Ges Pathol. 2007;91:243-9.
40. Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappaB. Oka D, etal., Int J Cancer. 2007 Jun 15;120(12):2576-81.
41. Increased nuclear factor-kappa B activation is related to the tumor development of renal cell carcinoma. Oya M, etal., Carcinogenesis. 2003 Mar;24(3):377-84.
42. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
43. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
44. Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy. Planavila A, etal., J Biol Chem. 2005 Apr 29;280(17):17464-71. Epub 2005 Feb 22.
45. Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction. Quiroz Y, etal., Am J Physiol Renal Physiol. 2008 Feb;294(2):F336-44. Epub 2007 Dec 12.
46. Nuclear factor-kappaB decoy amelioration of spinal cord injury-induced inflammation and behavior outcomes. Rafati DS, etal., J Neurosci Res. 2008 Feb 15;86(3):566-80.
47. MOLECULAR CLASSIFICATION OF BREAST CARCINOMA IN SITU. Raju U, etal., Curr Genomics. 2006 Dec;7(8):523-532.
48. Coexpression of Notch1 and NF-kappaB signaling pathway components in human cervical cancer progression. Ramdass B, etal., Gynecol Oncol. 2007 Feb;104(2):352-61. Epub 2006 Nov 13.
49. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
50. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
51. Expression of nuclear factor-kappa B and I kappa B alpha proteins in prostatic adenocarcinomas: correlation of nuclear factor-kappa B immunoreactivity with disease recurrence. Ross JS, etal., Clin Cancer Res. 2004 Apr 1;10(7):2466-72.
52. The Protective Effect of CAPE on Hepatic Ischemia/Reperfusion Injury in Rats. Saavedra-Lopes M, etal., J Surg Res. 2008 Mar 13.
53. A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats. Sawada H, etal., Chest. 2007 Oct;132(4):1265-74.
54. Effect of weight loss on proinflammatory state of mononuclear cells in obese women. Sheu WH, etal., Obesity (Silver Spring). 2008 May;16(5):1033-8. Epub 2008 Mar 6.
55. Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model. Shukla S, etal., Prostate. 2005 Aug 1;64(3):224-39.
56. ANTIAPOPTOTIC AND ANTI-INFLAMMATORY EFFECTS OF HYDROGEN SULFIDE IN A RAT MODEL OF REGIONAL MYOCARDIAL I/R. Sivarajah A, etal., Shock. 2008 Jul 16.
57. Diminished expression of transcription factors nuclear factor kappaB and CCAAT/enhancer binding protein underlies a novel tumor evasion mechanism affecting macrophages of mammary tumor-bearing mice. Torroella-Kouri M, etal., Cancer Res. 2005 Nov 15;65(22):10578-84.
58. Identification of a tumor-associated mutant form of the NF-kappaB RelA gene with reduced DNA-binding and transactivating activities. Trecca D, etal., Oncogene. 1997 Feb 20;14(7):791-9.
59. Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Tyagi A, etal., Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3248-55.
60. Demethylation of miR-9-3 and miR-193a genes suppresses proliferation and promotes apoptosis in non-small cell lung cancer cell lines. Wang J, etal., Cell Physiol Biochem. 2013;32(6):1707-19. doi: 10.1159/000356605. Epub 2013 Dec 13.
61. The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Wang W, etal., Clin Cancer Res. 1999 Jan;5(1):119-27.
62. Galantamine anti-colitic effect: Role of alpha-7 nicotinic acetylcholine receptor in modulating Jak/STAT3, NF-κB/HMGB1/RAGE and p-AKT/Bcl-2 pathways. Wazea SA, etal., Sci Rep. 2018 Mar 23;8(1):5110. doi: 10.1038/s41598-018-23359-6.
63. Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase. Wei Y, etal., Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E345-51. Epub 2007 Dec 11.
64. Ghrelin attenuates sepsis-induced acute lung injury and mortality in rats. Wu R, etal., Am J Respir Crit Care Med. 2007 Oct 15;176(8):805-13. Epub 2007 Jul 12.
65. Down-regulated CFTR During Aging Contributes to Benign Prostatic Hyperplasia. Xie C, etal., J Cell Physiol. 2015 Aug;230(8):1906-15. doi: 10.1002/jcp.24921.
66. Evidence for activation of nuclear factor kappaB in obstructive sleep apnea. Yamauchi M, etal., Sleep Breath. 2006 Dec;10(4):189-93.
67. [Molecular mechanism of berberine in improving insulin resistance induced by free fatty acid through inhibiting nuclear trascription factor-kappaB p65 in 3T3-L1 adipocytes] Yi P, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Dec;27(12):1099-104.
68. Pregnane X Receptor Not Nuclear Factor-kappa B Up-regulates P-glycoprotein Expression in the Brain of Chronic Epileptic Rats Induced by Kainic Acid. Yu N, etal., Neurochem Res. 2017 Aug;42(8):2167-2177. doi: 10.1007/s11064-017-2224-x. Epub 2017 Mar 16.
69. Gastrodin Ameliorates Acute Rejection via IRE1α/TRAF2/NF-κB in Rats Receiving Liver Allografts. Yuan F, etal., Biomed Res Int. 2019 Nov 20;2019:9276831. doi: 10.1155/2019/9276831. eCollection 2019.
70. Garlic Oil Suppressed Nitrosodiethylamine-Induced Hepatocarcinoma in Rats by Inhibiting PI3K-AKT-NF-κB Pathway. Zhang CL, etal., Int J Biol Sci. 2015 Apr 25;11(6):643-51. doi: 10.7150/ijbs.10785. eCollection 2015.
71. PANAX NOTOGINSENG SAPONINS ATTENUATE ATHEROSCLEROSIS IN RATS BY REGULATING THE BLOOD LIPID PROFILE AND AN ANTI-INFLAMMATORY ACTION. Zhang YG, etal., Clin Exp Pharmacol Physiol. 2008 Jul 9.
72. Losartan reduced connexin43 expression in left ventricular myocardium of spontaneously hypertensive rats. Zhao LL, etal., J Zhejiang Univ Sci B. 2008 Jun;9(6):448-54.
73. Distinct patterns of intracerebral hemorrhage-induced alterations in NF-kappaB subunit, iNOS, and COX-2 expression. Zhao X, etal., J Neurochem. 2007 May;101(3):652-63. Epub 2007 Jan 23.
Additional References at PubMed
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PMID:11160671   PMID:11231305   PMID:11241736   PMID:11274168   PMID:11278855   PMID:11287411   PMID:11299302   PMID:11313474   PMID:11385624   PMID:11387332   PMID:11395507   PMID:11511100  
PMID:11522182   PMID:11526476   PMID:11533489   PMID:11564889   PMID:11567019   PMID:11579140   PMID:11585920   PMID:11590148   PMID:11591705   PMID:11684013   PMID:11704662   PMID:11739381  
PMID:11813986   PMID:11827962   PMID:11833470   PMID:11880271   PMID:11922866   PMID:11931769   PMID:11953203   PMID:11964305   PMID:11967310   PMID:11970949   PMID:11971907   PMID:11976329  
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PMID:12398897   PMID:12403783   PMID:12414801   PMID:12419806   PMID:12419817   PMID:12427593   PMID:12429528   PMID:12444202   PMID:12456660   PMID:12471036   PMID:12473373   PMID:12477932  
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PMID:28364380   PMID:28378844   PMID:28407300   PMID:28414080   PMID:28416608   PMID:28418896   PMID:28428115   PMID:28440494   PMID:28465487   PMID:28466782   PMID:28514442   PMID:28537665  
PMID:28548219   PMID:28569771   PMID:28590547   PMID:28600438   PMID:28600541   PMID:28629334   PMID:28653238   PMID:28653898   PMID:28675108   PMID:28681591   PMID:28687276   PMID:28696292  
PMID:28718761   PMID:28762199   PMID:28766683   PMID:28772241   PMID:28817833   PMID:28825294   PMID:28831588   PMID:28844984   PMID:28847568   PMID:28923839   PMID:28990087   PMID:29017500  
PMID:29024797   PMID:29038521   PMID:29039556   PMID:29041983   PMID:29059172   PMID:29074539   PMID:29084252   PMID:29115381   PMID:29115409   PMID:29181822   PMID:29189925   PMID:29251177  
PMID:29305315   PMID:29311624   PMID:29336610   PMID:29363879   PMID:29388696   PMID:29410027   PMID:29428966   PMID:29439025   PMID:29463681   PMID:29525603   PMID:29532994   PMID:29592948  
PMID:29622796   PMID:29644893   PMID:29666362   PMID:29673591   PMID:29706626   PMID:29708732   PMID:29734393   PMID:29748061   PMID:29748238   PMID:29749134   PMID:29750422   PMID:29767266  
PMID:29784872   PMID:29785588   PMID:29813070   PMID:29916542   PMID:29945498   PMID:29959281   PMID:29968158   PMID:29991678   PMID:30017585   PMID:30026228   PMID:30029010   PMID:30049795  
PMID:30076618   PMID:30079603   PMID:30119172   PMID:30135182   PMID:30140708   PMID:30166344   PMID:30205516   PMID:30211233   PMID:30213788   PMID:30219682   PMID:30221732   PMID:30248551  
PMID:30293016   PMID:30300821   PMID:30304001   PMID:30325077   PMID:30332797   PMID:30362505   PMID:30375448   PMID:30387173   PMID:30398029   PMID:30455355   PMID:30496749   PMID:30527665  
PMID:30542119   PMID:30553016   PMID:30562971   PMID:30585266   PMID:30619335   PMID:30628021   PMID:30653501   PMID:30659266   PMID:30670829   PMID:30704857   PMID:30717343   PMID:30717434  
PMID:30762338   PMID:30766526   PMID:30798416   PMID:30808715   PMID:30825051   PMID:30869196   PMID:30937967   PMID:30946927   PMID:30978403   PMID:30983127   PMID:30989475   PMID:30995931  
PMID:31005254   PMID:31092435   PMID:31128029   PMID:31130368   PMID:31229617   PMID:31262971   PMID:31265453   PMID:31281309   PMID:31299491   PMID:31308481   PMID:31322430   PMID:31351496  
PMID:31382678   PMID:31391242   PMID:31391462   PMID:31393268   PMID:31415393   PMID:31427673   PMID:31484794   PMID:31527615   PMID:31545447   PMID:31561304   PMID:31572379   PMID:31582729  
PMID:31586073   PMID:31606566   PMID:31626775   PMID:31626956   PMID:31636124   PMID:31636182   PMID:31652441   PMID:31676369   PMID:31698141   PMID:31723122   PMID:31724445   PMID:31730277  
PMID:31754246   PMID:31759055   PMID:31769216   PMID:31802034   PMID:31906441   PMID:31958511   PMID:31992226   PMID:31999475   PMID:32003539   PMID:32015337   PMID:32038638   PMID:32041737  
PMID:32060423   PMID:32124932   PMID:32183905   PMID:32187412   PMID:32207045   PMID:32217689   PMID:32232831   PMID:32240617   PMID:32277133   PMID:32296183   PMID:32319559   PMID:32325032  
PMID:32364285   PMID:32391793   PMID:32502356   PMID:32512041   PMID:32513696   PMID:32514758   PMID:32546717   PMID:32572027   PMID:32575582   PMID:32587091   PMID:32657001   PMID:32687490  
PMID:32737283   PMID:32754266   PMID:32814053   PMID:32894380   PMID:32911434   PMID:32912968   PMID:32945499   PMID:32969189   PMID:33038311   PMID:33060567   PMID:33067267   PMID:33126183  
PMID:33143574   PMID:33166679   PMID:33279869   PMID:33309857   PMID:33323971   PMID:33417952   PMID:33417976   PMID:33420370   PMID:33446690   PMID:33460751   PMID:33478005   PMID:33502650  
PMID:33512636   PMID:33536546   PMID:33576087   PMID:33617838   PMID:33685520   PMID:33710605   PMID:33754058   PMID:33756273   PMID:33760140   PMID:33805981   PMID:33857149   PMID:33859619  
PMID:33903120   PMID:33961781   PMID:34047468   PMID:34089216   PMID:34100597   PMID:34155144   PMID:34182081   PMID:34216805   PMID:34219129   PMID:34382737   PMID:34405442   PMID:34412704  
PMID:34419501   PMID:34463587   PMID:34465889   PMID:34697371   PMID:34740611   PMID:34807912   PMID:34824310   PMID:34881782   PMID:34908452   PMID:34917906   PMID:35122005   PMID:35140242  
PMID:35166167   PMID:35176168   PMID:35210364   PMID:35256949   PMID:35271311   PMID:35346238   PMID:35391932   PMID:35396527   PMID:35458235   PMID:35509820   PMID:35688944   PMID:35696571  
PMID:35709258   PMID:35831314   PMID:35844135   PMID:35944360   PMID:35981571   PMID:36055411   PMID:36096861   PMID:36114006   PMID:36116131   PMID:36168628   PMID:36208777   PMID:36215168  
PMID:36273237   PMID:36398858   PMID:36548402   PMID:36567907   PMID:36607699   PMID:36629882   PMID:36789977   PMID:36820829   PMID:36926348   PMID:36931391   PMID:37038032   PMID:37175530  
PMID:37185280   PMID:37199168   PMID:37203408   PMID:37273177   PMID:37311878   PMID:37454278   PMID:37541772   PMID:37586455   PMID:37716704   PMID:37730133   PMID:37793472   PMID:37856812  
PMID:37858201   PMID:38284203   PMID:38360128   PMID:38367599   PMID:38473959   PMID:38504985   PMID:38514058  


Genomics

Comparative Map Data
RELA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,653,601 - 65,663,857 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,653,599 - 65,663,090 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,421,072 - 65,430,387 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,178,393 - 65,186,951 (-)NCBINCBI36Build 36hg18NCBI36
Build 341165,178,392 - 65,186,951NCBI
Celera1162,747,772 - 62,757,128 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,748,056 - 61,757,436 (-)NCBIHuRef
CHM1_11165,305,002 - 65,314,374 (-)NCBICHM1_1
T2T-CHM13v2.01165,647,771 - 65,658,027 (-)NCBIT2T-CHM13v2.0
Rela
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,686,993 - 5,698,162 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,687,511 - 5,698,158 (+)EnsemblGRCm39 Ensembl
GRCm38195,637,442 - 5,648,134 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,637,483 - 5,648,130 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,637,490 - 5,648,130 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,637,490 - 5,648,130 (+)NCBIMGSCv36mm8
Celera195,507,082 - 5,517,707 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
Rela
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,354,336 - 212,364,815 (+)NCBIGRCr8
mRatBN7.21202,925,001 - 202,935,484 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,924,945 - 202,935,484 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,277,590 - 211,288,062 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,370,406 - 218,380,885 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,061,451 - 211,071,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,992,770 - 221,003,249 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,992,770 - 221,003,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,928,092 - 227,938,571 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,262,669 - 208,273,148 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11208,416,121 - 208,426,601 (+)NCBI
Celera1200,460,753 - 200,471,232 (+)NCBICelera
Cytogenetic Map1q43NCBI
Rela
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,603,345 - 19,611,516 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,602,930 - 19,612,263 (+)NCBIChiLan1.0ChiLan1.0
RELA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2966,883,435 - 66,892,833 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,926,207 - 67,935,595 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,012,839 - 61,022,225 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,347,859 - 64,357,461 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,347,859 - 64,356,868 (-)Ensemblpanpan1.1panPan2
RELA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,550,003 - 51,558,861 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,550,040 - 51,558,875 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,158,512 - 50,167,377 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,587,297 - 52,596,161 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,587,329 - 52,596,159 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,687,144 - 51,696,009 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,261,264 - 51,270,127 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,051,615 - 52,060,481 (+)NCBIUU_Cfam_GSD_1.0
Rela
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,359,432 - 7,368,234 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,801,636 - 3,809,813 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,800,142 - 3,810,583 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RELA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,593,969 - 6,603,469 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,594,869 - 6,602,684 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,699,452 - 5,707,267 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RELA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,576,059 - 8,585,561 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18,576,542 - 8,586,516 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,871,180 - 105,881,402 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rela
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,732,938 - 20,741,272 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,732,813 - 20,742,016 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RELA
333 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_021975.4(RELA):c.1006dup (p.Arg336fs) duplication Mucocutaneous ulceration, chronic [RCV003159250] Chr11:65655714..65655715 [GRCh38]
Chr11:65423185..65423186 [GRCh37]
Chr11:11q13.1
pathogenic
GRCh38/hg38 11q13.1(chr11:65520831-65695349)x3 copy number gain See cases [RCV000141174] Chr11:65520831..65695349 [GRCh38]
Chr11:65288302..65462820 [GRCh37]
Chr11:65044878..65219396 [NCBI36]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.329T>C (p.Ile110Thr) single nucleotide variant Childhood-onset schizophrenia [RCV000202330] Chr11:65661693 [GRCh38]
Chr11:65429164 [GRCh37]
Chr11:11q13.1
likely pathogenic
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25
pathogenic
NM_021975.4(RELA):c.1459del (p.His487fs) deletion Mucocutaneous ulceration, chronic [RCV003159249] Chr11:65654575 [GRCh38]
Chr11:65422046 [GRCh37]
Chr11:11q13.1
pathogenic
GRCh37/hg19 11q13.1-13.2(chr11:64501919-67129258)x3 copy number gain See cases [RCV000511632] Chr11:64501919..67129258 [GRCh37]
Chr11:11q13.1-13.2
likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_021975.4(RELA):c.1080T>C (p.Tyr360=) single nucleotide variant Mucocutaneous ulceration, chronic [RCV003224422]|RELA-related condition [RCV003938150]|not provided [RCV000768068] Chr11:65654954 [GRCh38]
Chr11:65422425 [GRCh37]
Chr11:11q13.1
benign|conflicting interpretations of pathogenicity|uncertain significance
NM_021975.4(RELA):c.719C>T (p.Ser240Leu) single nucleotide variant Inborn genetic diseases [RCV003266723] Chr11:65658445 [GRCh38]
Chr11:65425916 [GRCh37]
Chr11:11q13.1
uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_021975.4(RELA):c.559+1G>A single nucleotide variant Mucocutaneous ulceration, chronic [RCV000754619] Chr11:65659665 [GRCh38]
Chr11:65427136 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.736C>T (p.Arg246Ter) single nucleotide variant not provided [RCV000754618] Chr11:65658428 [GRCh38]
Chr11:65425899 [GRCh37]
Chr11:11q13.1
pathogenic|uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q13.1(chr11:65347930-65421892)x3 copy number gain not provided [RCV000750084] Chr11:65347930..65421892 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1653C>T (p.Ser551=) single nucleotide variant RELA-related condition [RCV003932904]|not provided [RCV000905695] Chr11:65654381 [GRCh38]
Chr11:65421852 [GRCh37]
Chr11:11q13.1
benign
dup(11)(q13.1q13.1) duplication Ependymoma [RCV000785872] Chr11:63533279..65429676 [GRCh37]
Chr11:11q13.1
likely pathogenic
NM_021975.4(RELA):c.1008C>T (p.Arg336=) single nucleotide variant Mucocutaneous ulceration, chronic [RCV003224423]|not provided [RCV000768069] Chr11:65655713 [GRCh38]
Chr11:65423184 [GRCh37]
Chr11:11q13.1
likely benign|conflicting interpretations of pathogenicity|uncertain significance
GRCh37/hg19 11q13.1-13.2(chr11:65138976-67574402) copy number gain not provided [RCV000767601] Chr11:65138976..67574402 [GRCh37]
Chr11:11q13.1-13.2
pathogenic
NM_021975.4(RELA):c.1527G>A (p.Arg509=) single nucleotide variant not provided [RCV000894860] Chr11:65654507 [GRCh38]
Chr11:65421978 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.54C>T (p.Gly18=) single nucleotide variant not provided [RCV000930842] Chr11:65662069 [GRCh38]
Chr11:65429540 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.456C>T (p.Tyr152=) single nucleotide variant RELA-related condition [RCV003910857]|not provided [RCV000907639] Chr11:65659769 [GRCh38]
Chr11:65427240 [GRCh37]
Chr11:11q13.1
benign|likely benign
NM_021975.4(RELA):c.871G>A (p.Asp291Asn) single nucleotide variant Mucocutaneous ulceration, chronic [RCV002488062]|RELA-related condition [RCV003972966]|not provided [RCV000974469] Chr11:65658293 [GRCh38]
Chr11:65425764 [GRCh37]
Chr11:11q13.1
benign|likely benign
NM_021975.4(RELA):c.706C>T (p.Arg236Ter) single nucleotide variant RELA-related condition [RCV003396687]|not provided [RCV001055525] Chr11:65658458 [GRCh38]
Chr11:65425929 [GRCh37]
Chr11:11q13.1
pathogenic|likely pathogenic
NM_021975.4(RELA):c.592C>T (p.Arg198Ter) single nucleotide variant Mucocutaneous ulceration, chronic [RCV003147591]|not provided [RCV001092067] Chr11:65658790 [GRCh38]
Chr11:65426261 [GRCh37]
Chr11:11q13.1
pathogenic|likely pathogenic
NC_000011.9:g.(?_64973914)_(70052579_?)dup duplication Aicardi-Goutieres syndrome 3 [RCV003113322]|FADD-related immunodeficiency [RCV003107753] Chr11:64973914..70052579 [GRCh37]
Chr11:11q13.1-13.3
uncertain significance
NM_021975.4(RELA):c.1470G>A (p.Glu490=) single nucleotide variant not provided [RCV001532643] Chr11:65654564 [GRCh38]
Chr11:65422035 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1000C>T (p.Pro334Ser) single nucleotide variant not provided [RCV001532644] Chr11:65655721 [GRCh38]
Chr11:65423192 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1034-2A>C single nucleotide variant Mucocutaneous ulceration [RCV000853280] Chr11:65655002 [GRCh38]
Chr11:65422473 [GRCh37]
Chr11:11q13.1
likely pathogenic
NM_021975.4(RELA):c.559+8G>T single nucleotide variant Mucocutaneous ulceration, chronic [RCV003224515]|not provided [RCV003768925] Chr11:65659658 [GRCh38]
Chr11:65427129 [GRCh37]
Chr11:11q13.1
likely benign|uncertain significance
NM_021975.4(RELA):c.1613C>T (p.Ala538Val) single nucleotide variant not provided [RCV001314272] Chr11:65654421 [GRCh38]
Chr11:65421892 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.576C>T (p.Ala192=) single nucleotide variant not provided [RCV001310605] Chr11:65658806 [GRCh38]
Chr11:65426277 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1080T>G (p.Tyr360Ter) single nucleotide variant not provided [RCV001373637] Chr11:65654954 [GRCh38]
Chr11:65422425 [GRCh37]
Chr11:11q13.1
pathogenic|uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3
pathogenic
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Familial temporal lobe epilepsy 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3
uncertain significance
NM_021975.4(RELA):c.958+11G>A single nucleotide variant not provided [RCV001435306] Chr11:65655844 [GRCh38]
Chr11:65423315 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.665-14C>T single nucleotide variant not provided [RCV001519983] Chr11:65658513 [GRCh38]
Chr11:65425984 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1259C>T (p.Ala420Val) single nucleotide variant not provided [RCV001492651] Chr11:65654775 [GRCh38]
Chr11:65422246 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.958+17G>A single nucleotide variant not provided [RCV001523758] Chr11:65655838 [GRCh38]
Chr11:65423309 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1131G>A (p.Ser377=) single nucleotide variant RELA-related condition [RCV003921173]|not provided [RCV001522201] Chr11:65654903 [GRCh38]
Chr11:65422374 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1034-15G>C single nucleotide variant not provided [RCV001513278] Chr11:65655015 [GRCh38]
Chr11:65422486 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1033+11C>T single nucleotide variant not provided [RCV001393011] Chr11:65655677 [GRCh38]
Chr11:65423148 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1633C>T (p.Leu545=) single nucleotide variant not provided [RCV001532642] Chr11:65654401 [GRCh38]
Chr11:65421872 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.985C>T (p.Arg329Ter) single nucleotide variant Mucocutaneous ulceration, chronic [RCV002250758]|not provided [RCV001388963] Chr11:65655736 [GRCh38]
Chr11:65423207 [GRCh37]
Chr11:11q13.1
pathogenic|likely pathogenic
NM_021975.4(RELA):c.669C>T (p.Asp223=) single nucleotide variant not provided [RCV001485529] Chr11:65658495 [GRCh38]
Chr11:65425966 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.833G>A (p.Arg278Gln) single nucleotide variant not provided [RCV001490694] Chr11:65658331 [GRCh38]
Chr11:65425802 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.34+16G>A single nucleotide variant not provided [RCV001519657] Chr11:65662163 [GRCh38]
Chr11:65429634 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.8-10C>T single nucleotide variant Mucocutaneous ulceration, chronic [RCV002506620]|not provided [RCV001517074] Chr11:65662215 [GRCh38]
Chr11:65429686 [GRCh37]
Chr11:11q13.1
benign|likely benign
NM_021975.4(RELA):c.1033+6del deletion RELA-related condition [RCV003940928]|not provided [RCV001515655] Chr11:65655682 [GRCh38]
Chr11:65423153 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1052T>G (p.Phe351Cys) single nucleotide variant not provided [RCV002009065] Chr11:65654982 [GRCh38]
Chr11:65422453 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1520C>T (p.Ala507Val) single nucleotide variant not provided [RCV002021476] Chr11:65654514 [GRCh38]
Chr11:65421985 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.445C>T (p.Arg149Cys) single nucleotide variant not provided [RCV002006135] Chr11:65659780 [GRCh38]
Chr11:65427251 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.818G>A (p.Arg273Gln) single nucleotide variant not provided [RCV001895020] Chr11:65658346 [GRCh38]
Chr11:65425817 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1297G>A (p.Glu433Lys) single nucleotide variant not provided [RCV001950045] Chr11:65654737 [GRCh38]
Chr11:65422208 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.385G>A (p.Ala129Thr) single nucleotide variant not provided [RCV001915384] Chr11:65660166 [GRCh38]
Chr11:65427637 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.676G>A (p.Val226Met) single nucleotide variant not provided [RCV001896758] Chr11:65658488 [GRCh38]
Chr11:65425959 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.967G>A (p.Asp323Asn) single nucleotide variant not provided [RCV002045196] Chr11:65655754 [GRCh38]
Chr11:65423225 [GRCh37]
Chr11:11q13.1
uncertain significance
GRCh37/hg19 11q13.1-13.2(chr11:64935724-66405514) copy number loss not specified [RCV002052930] Chr11:64935724..66405514 [GRCh37]
Chr11:11q13.1-13.2
uncertain significance
NM_021975.4(RELA):c.1519del (p.Ala507fs) deletion not provided [RCV001874020] Chr11:65654515 [GRCh38]
Chr11:65421986 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1537C>G (p.Pro513Ala) single nucleotide variant not provided [RCV001909318] Chr11:65654497 [GRCh38]
Chr11:65421968 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.520C>T (p.Arg174Cys) single nucleotide variant not provided [RCV002040473] Chr11:65659705 [GRCh38]
Chr11:65427176 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.596T>C (p.Val199Ala) single nucleotide variant Mucocutaneous ulceration, chronic [RCV001839219]|not provided [RCV002077325] Chr11:65658786 [GRCh38]
Chr11:65426257 [GRCh37]
Chr11:11q13.1
likely benign|uncertain significance
NC_000011.9:g.(?_64522783)_(66283694_?)del deletion Bardet-Biedl syndrome [RCV002014493]|Glycogen storage disease, type V [RCV002004587] Chr11:64522783..66283694 [GRCh37]
Chr11:11q13.1-13.2
pathogenic
NM_021975.4(RELA):c.286C>T (p.Arg96Trp) single nucleotide variant not provided [RCV001965660] Chr11:65661736 [GRCh38]
Chr11:65429207 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.915A>G (p.Thr305=) single nucleotide variant not provided [RCV001945633] Chr11:65655898 [GRCh38]
Chr11:65423369 [GRCh37]
Chr11:11q13.1
likely benign|uncertain significance
NM_021975.4(RELA):c.959-3C>T single nucleotide variant not provided [RCV001912258] Chr11:65655765 [GRCh38]
Chr11:65423236 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.113_114delinsAA (p.Cys38Ter) indel not provided [RCV001913491] Chr11:65662009..65662010 [GRCh38]
Chr11:65429480..65429481 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1537C>A (p.Pro513Thr) single nucleotide variant Inborn genetic diseases [RCV003355729]|not provided [RCV001985954] Chr11:65654497 [GRCh38]
Chr11:65421968 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1495G>T (p.Ala499Ser) single nucleotide variant not provided [RCV002040620] Chr11:65654539 [GRCh38]
Chr11:65422010 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.619C>G (p.Leu207Val) single nucleotide variant not provided [RCV001909006] Chr11:65658763 [GRCh38]
Chr11:65426234 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.446G>A (p.Arg149His) single nucleotide variant not provided [RCV001963712] Chr11:65659779 [GRCh38]
Chr11:65427250 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.957C>T (p.Ser319=) single nucleotide variant not provided [RCV001936745] Chr11:65655856 [GRCh38]
Chr11:65423327 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1153C>T (p.Gln385Ter) single nucleotide variant not provided [RCV001999801] Chr11:65654881 [GRCh38]
Chr11:65422352 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1171C>T (p.Pro391Ser) single nucleotide variant not provided [RCV001888562] Chr11:65654863 [GRCh38]
Chr11:65422334 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.34+5G>A single nucleotide variant not provided [RCV002000489] Chr11:65662174 [GRCh38]
Chr11:65429645 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.330C>G (p.Ile110Met) single nucleotide variant Inborn genetic diseases [RCV002548114]|not provided [RCV002038217] Chr11:65661692 [GRCh38]
Chr11:65429163 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.35-5G>A single nucleotide variant not provided [RCV001974642] Chr11:65662093 [GRCh38]
Chr11:65429564 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1416dup (p.Glu473fs) duplication not provided [RCV002000169] Chr11:65654617..65654618 [GRCh38]
Chr11:65422088..65422089 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1468G>A (p.Glu490Lys) single nucleotide variant not provided [RCV001880395] Chr11:65654566 [GRCh38]
Chr11:65422037 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1244C>T (p.Pro415Leu) single nucleotide variant not provided [RCV002016870] Chr11:65654790 [GRCh38]
Chr11:65422261 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1010G>A (p.Ser337Asn) single nucleotide variant not provided [RCV001988933] Chr11:65655711 [GRCh38]
Chr11:65423182 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1533dup (p.Asp512fs) duplication not provided [RCV002031355] Chr11:65654500..65654501 [GRCh38]
Chr11:65421971..65421972 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.974G>A (p.Arg325Gln) single nucleotide variant Inborn genetic diseases [RCV002555391]|not provided [RCV001903556] Chr11:65655747 [GRCh38]
Chr11:65423218 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1018T>C (p.Ser340Pro) single nucleotide variant not provided [RCV001867029] Chr11:65655703 [GRCh38]
Chr11:65423174 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.791C>T (p.Ala264Val) single nucleotide variant Inborn genetic diseases [RCV003264143]|RELA-related condition [RCV003948779]|not provided [RCV001907435] Chr11:65658373 [GRCh38]
Chr11:65425844 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.331C>T (p.His111Tyr) single nucleotide variant not provided [RCV001901870] Chr11:65661691 [GRCh38]
Chr11:65429162 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1461C>A (p.His487Gln) single nucleotide variant not provided [RCV002019451] Chr11:65654573 [GRCh38]
Chr11:65422044 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.335+17C>T single nucleotide variant not provided [RCV002049558] Chr11:65661670 [GRCh38]
Chr11:65429141 [GRCh37]
Chr11:11q13.1
likely benign|uncertain significance
NM_021975.4(RELA):c.59A>G (p.Tyr20Cys) single nucleotide variant not provided [RCV001993929] Chr11:65662064 [GRCh38]
Chr11:65429535 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.217C>T (p.Arg73Cys) single nucleotide variant not provided [RCV001988881] Chr11:65661805 [GRCh38]
Chr11:65429276 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.115G>T (p.Glu39Ter) single nucleotide variant not provided [RCV001953505] Chr11:65662008 [GRCh38]
Chr11:65429479 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.800G>A (p.Arg267His) single nucleotide variant not provided [RCV001955081] Chr11:65658364 [GRCh38]
Chr11:65425835 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1442G>A (p.Gly481Asp) single nucleotide variant not provided [RCV001923674] Chr11:65654592 [GRCh38]
Chr11:65422063 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1137GGCCCC[3] (p.380AP[3]) microsatellite not provided [RCV001904420] Chr11:65654885..65654886 [GRCh38]
Chr11:65422356..65422357 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.428-18C>A single nucleotide variant not provided [RCV002011197] Chr11:65659815 [GRCh38]
Chr11:65427286 [GRCh37]
Chr11:11q13.1
likely benign|uncertain significance
NM_021975.4(RELA):c.890G>A (p.Arg297Gln) single nucleotide variant not provided [RCV001957458] Chr11:65655923 [GRCh38]
Chr11:65423394 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.965C>G (p.Thr322Ser) single nucleotide variant not provided [RCV002017795] Chr11:65655756 [GRCh38]
Chr11:65423227 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.877+6C>G single nucleotide variant not provided [RCV001959565] Chr11:65658281 [GRCh38]
Chr11:65425752 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.494T>C (p.Val165Ala) single nucleotide variant not provided [RCV001884388] Chr11:65659731 [GRCh38]
Chr11:65427202 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1130C>T (p.Ser377Leu) single nucleotide variant not provided [RCV001940798] Chr11:65654904 [GRCh38]
Chr11:65422375 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.937A>G (p.Met313Val) single nucleotide variant not provided [RCV001934080] Chr11:65655876 [GRCh38]
Chr11:65423347 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1261G>C (p.Val421Leu) single nucleotide variant not provided [RCV002048183] Chr11:65654773 [GRCh38]
Chr11:65422244 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.853G>T (p.Glu285Ter) single nucleotide variant not provided [RCV001975066] Chr11:65658311 [GRCh38]
Chr11:65425782 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.341A>G (p.Gln114Arg) single nucleotide variant not provided [RCV001900371] Chr11:65660210 [GRCh38]
Chr11:65427681 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.577G>A (p.Glu193Lys) single nucleotide variant not provided [RCV001989491] Chr11:65658805 [GRCh38]
Chr11:65426276 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.878-8T>C single nucleotide variant not provided [RCV002090088] Chr11:65655943 [GRCh38]
Chr11:65423414 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.187-10C>T single nucleotide variant not provided [RCV002129991] Chr11:65661845 [GRCh38]
Chr11:65429316 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1335T>C (p.Phe445=) single nucleotide variant not provided [RCV002192200] Chr11:65654699 [GRCh38]
Chr11:65422170 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1587A>G (p.Ser529=) single nucleotide variant not provided [RCV002104446] Chr11:65654447 [GRCh38]
Chr11:65421918 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.180C>T (p.Thr60=) single nucleotide variant not provided [RCV002074593] Chr11:65661943 [GRCh38]
Chr11:65429414 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1416C>T (p.Ser472=) single nucleotide variant not provided [RCV002128468] Chr11:65654618 [GRCh38]
Chr11:65422089 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.34+13C>T single nucleotide variant not provided [RCV002165700] Chr11:65662166 [GRCh38]
Chr11:65429637 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1506C>T (p.Arg502=) single nucleotide variant not provided [RCV002208123] Chr11:65654528 [GRCh38]
Chr11:65421999 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.959-17T>C single nucleotide variant not provided [RCV002166541] Chr11:65655779 [GRCh38]
Chr11:65423250 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.35-19C>T single nucleotide variant not provided [RCV002206185] Chr11:65662107 [GRCh38]
Chr11:65429578 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1404C>A (p.Ser468=) single nucleotide variant not provided [RCV002126408] Chr11:65654630 [GRCh38]
Chr11:65422101 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.951T>C (p.Pro317=) single nucleotide variant not provided [RCV002109310] Chr11:65655862 [GRCh38]
Chr11:65423333 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.187-32_187-20del deletion not provided [RCV002187137] Chr11:65661855..65661867 [GRCh38]
Chr11:65429326..65429338 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.966C>T (p.Thr322=) single nucleotide variant not provided [RCV002208228] Chr11:65655755 [GRCh38]
Chr11:65423226 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.34+19G>C single nucleotide variant not provided [RCV002167462] Chr11:65662160 [GRCh38]
Chr11:65429631 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1122C>T (p.Ser374=) single nucleotide variant not provided [RCV002187952] Chr11:65654912 [GRCh38]
Chr11:65422383 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.225C>T (p.Ser75=) single nucleotide variant not provided [RCV002194220] Chr11:65661797 [GRCh38]
Chr11:65429268 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.664+14G>A single nucleotide variant not provided [RCV002127408] Chr11:65658704 [GRCh38]
Chr11:65426175 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1008C>A (p.Arg336=) single nucleotide variant not provided [RCV002193820] Chr11:65655713 [GRCh38]
Chr11:65423184 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.664+7A>G single nucleotide variant not provided [RCV002193431] Chr11:65658711 [GRCh38]
Chr11:65426182 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1305G>A (p.Thr435=) single nucleotide variant not provided [RCV002097579] Chr11:65654729 [GRCh38]
Chr11:65422200 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1533C>T (p.Pro511=) single nucleotide variant not provided [RCV002216227] Chr11:65654501 [GRCh38]
Chr11:65421972 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.369G>A (p.Lys123=) single nucleotide variant not provided [RCV002205574] Chr11:65660182 [GRCh38]
Chr11:65427653 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.879C>T (p.Asp293=) single nucleotide variant not provided [RCV002126559] Chr11:65655934 [GRCh38]
Chr11:65423405 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.958+15G>C single nucleotide variant not provided [RCV002078801] Chr11:65655840 [GRCh38]
Chr11:65423311 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.435A>C (p.Ile145=) single nucleotide variant not provided [RCV002171601] Chr11:65659790 [GRCh38]
Chr11:65427261 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.559+18C>T single nucleotide variant not provided [RCV002174032] Chr11:65659648 [GRCh38]
Chr11:65427119 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.560-14T>C single nucleotide variant not provided [RCV002134184] Chr11:65658836 [GRCh38]
Chr11:65426307 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.729T>C (p.Asp243=) single nucleotide variant RELA-related condition [RCV003984189]|not provided [RCV002105058] Chr11:65658435 [GRCh38]
Chr11:65425906 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1034-19C>G single nucleotide variant not provided [RCV002197354] Chr11:65655019 [GRCh38]
Chr11:65422490 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1458C>A (p.Pro486=) single nucleotide variant not provided [RCV002115520] Chr11:65654576 [GRCh38]
Chr11:65422047 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.351A>C (p.Gly117=) single nucleotide variant not provided [RCV002213102] Chr11:65660200 [GRCh38]
Chr11:65427671 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1017T>C (p.Ala339=) single nucleotide variant not provided [RCV002092533] Chr11:65655704 [GRCh38]
Chr11:65423175 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.771C>T (p.Tyr257=) single nucleotide variant not provided [RCV002151731] Chr11:65658393 [GRCh38]
Chr11:65425864 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.900G>A (p.Glu300=) single nucleotide variant not provided [RCV002086951] Chr11:65655913 [GRCh38]
Chr11:65423384 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1327C>T (p.Leu443=) single nucleotide variant RELA-related condition [RCV003978868]|not provided [RCV002151788] Chr11:65654707 [GRCh38]
Chr11:65422178 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.720G>A (p.Ser240=) single nucleotide variant not provided [RCV002210239] Chr11:65658444 [GRCh38]
Chr11:65425915 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.428-17G>T single nucleotide variant not provided [RCV002095676] Chr11:65659814 [GRCh38]
Chr11:65427285 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1539A>G (p.Pro513=) single nucleotide variant RELA-related condition [RCV003971025]|not provided [RCV002108921] Chr11:65654495 [GRCh38]
Chr11:65421966 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.615C>T (p.Ser205=) single nucleotide variant not provided [RCV002077401] Chr11:65658767 [GRCh38]
Chr11:65426238 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.597G>A (p.Val199=) single nucleotide variant not provided [RCV002085502] Chr11:65658785 [GRCh38]
Chr11:65426256 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.831C>T (p.Asp277=) single nucleotide variant RELA-related condition [RCV003941318]|not provided [RCV002189567] Chr11:65658333 [GRCh38]
Chr11:65425804 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.768C>A (p.Pro256=) single nucleotide variant not provided [RCV002178414] Chr11:65658396 [GRCh38]
Chr11:65425867 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.336-7C>T single nucleotide variant not provided [RCV002160828] Chr11:65660222 [GRCh38]
Chr11:65427693 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.903A>G (p.Lys301=) single nucleotide variant not provided [RCV002199063] Chr11:65655910 [GRCh38]
Chr11:65423381 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.336-16G>A single nucleotide variant not provided [RCV002181202] Chr11:65660231 [GRCh38]
Chr11:65427702 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.636C>T (p.Ile212=) single nucleotide variant not provided [RCV002182297] Chr11:65658746 [GRCh38]
Chr11:65426217 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.501C>T (p.Asp167=) single nucleotide variant not provided [RCV002179061] Chr11:65659724 [GRCh38]
Chr11:65427195 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1296G>A (p.Gly432=) single nucleotide variant not provided [RCV002081468] Chr11:65654738 [GRCh38]
Chr11:65422209 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.335+18T>C single nucleotide variant not provided [RCV002141020] Chr11:65661669 [GRCh38]
Chr11:65429140 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.357G>A (p.Gln119=) single nucleotide variant not provided [RCV002154598] Chr11:65660194 [GRCh38]
Chr11:65427665 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.528G>A (p.Pro176=) single nucleotide variant not provided [RCV002181260] Chr11:65659697 [GRCh38]
Chr11:65427168 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1582C>A (p.Leu528Ile) single nucleotide variant not provided [RCV002219262] Chr11:65654452 [GRCh38]
Chr11:65421923 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1065G>A (p.Leu355=) single nucleotide variant not provided [RCV002181536] Chr11:65654969 [GRCh38]
Chr11:65422440 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.7+11C>T single nucleotide variant not provided [RCV002099425] Chr11:65662815 [GRCh38]
Chr11:65430286 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.884G>A (p.Arg295His) single nucleotide variant not provided [RCV002219528] Chr11:65655929 [GRCh38]
Chr11:65423400 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.645G>C (p.Leu215=) single nucleotide variant not provided [RCV002219905] Chr11:65658737 [GRCh38]
Chr11:65426208 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.450G>A (p.Gly150=) single nucleotide variant not provided [RCV002180142] Chr11:65659775 [GRCh38]
Chr11:65427246 [GRCh37]
Chr11:11q13.1
likely benign
NC_000011.9:g.(?_65325080)_(65639825_?)del deletion Aicardi-Goutieres syndrome 3 [RCV003119977]|not provided [RCV003109848] Chr11:65325080..65639825 [GRCh37]
Chr11:11q13.1
pathogenic|uncertain significance|no classifications from unflagged records
NC_000011.9:g.(?_65429138)_(65430303_?)del deletion not provided [RCV003109849] Chr11:65429138..65430303 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1140C>T (p.Ala380=) single nucleotide variant not provided [RCV003115262] Chr11:65654894 [GRCh38]
Chr11:65422365 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1404C>T (p.Ser468=) single nucleotide variant not provided [RCV003116184] Chr11:65654630 [GRCh38]
Chr11:65422101 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1528C>T (p.Pro510Ser) single nucleotide variant not provided [RCV002296778] Chr11:65654506 [GRCh38]
Chr11:65421977 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1346A>C (p.Asp449Ala) single nucleotide variant not provided [RCV002298348] Chr11:65654688 [GRCh38]
Chr11:65422159 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1519G>A (p.Ala507Thr) single nucleotide variant not provided [RCV002295084] Chr11:65654515 [GRCh38]
Chr11:65421986 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.820C>T (p.Arg274Trp) single nucleotide variant not provided [RCV002303036] Chr11:65658344 [GRCh38]
Chr11:65425815 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.917A>G (p.Tyr306Cys) single nucleotide variant RELA-related condition [RCV003973380]|not provided [RCV002295822] Chr11:65655896 [GRCh38]
Chr11:65423367 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.97C>T (p.Arg33Cys) single nucleotide variant not provided [RCV002296204] Chr11:65662026 [GRCh38]
Chr11:65429497 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.428-16C>T single nucleotide variant not provided [RCV002881309] Chr11:65659813 [GRCh38]
Chr11:65427284 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1034-15_1034-12del deletion not provided [RCV002776025] Chr11:65655012..65655015 [GRCh38]
Chr11:65422483..65422486 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.234C>T (p.Thr78=) single nucleotide variant not provided [RCV002730415] Chr11:65661788 [GRCh38]
Chr11:65429259 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1423C>G (p.Gln475Glu) single nucleotide variant not provided [RCV002731539] Chr11:65654611 [GRCh38]
Chr11:65422082 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.144C>T (p.Gly48=) single nucleotide variant not provided [RCV002861858] Chr11:65661979 [GRCh38]
Chr11:65429450 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.181A>G (p.Ile61Val) single nucleotide variant not provided [RCV003011791] Chr11:65661942 [GRCh38]
Chr11:65429413 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.961C>T (p.Pro321Ser) single nucleotide variant not provided [RCV002726795] Chr11:65655760 [GRCh38]
Chr11:65423231 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1053T>C (p.Phe351=) single nucleotide variant not provided [RCV003016713] Chr11:65654981 [GRCh38]
Chr11:65422452 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1293T>G (p.Ala431=) single nucleotide variant not provided [RCV002858481] Chr11:65654741 [GRCh38]
Chr11:65422212 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.240C>T (p.Asp80=) single nucleotide variant not provided [RCV002776056] Chr11:65661782 [GRCh38]
Chr11:65429253 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1140C>A (p.Ala380=) single nucleotide variant not provided [RCV002843735] Chr11:65654894 [GRCh38]
Chr11:65422365 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1655A>G (p.Ter552=) single nucleotide variant not provided [RCV003017296] Chr11:65654379 [GRCh38]
Chr11:65421850 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.776A>G (p.Asp259Gly) single nucleotide variant not provided [RCV003095839] Chr11:65658388 [GRCh38]
Chr11:65425859 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.189C>A (p.Ile63=) single nucleotide variant not provided [RCV002618317] Chr11:65661833 [GRCh38]
Chr11:65429304 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.335+13C>T single nucleotide variant not provided [RCV002613680] Chr11:65661674 [GRCh38]
Chr11:65429145 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.45G>A (p.Gln15=) single nucleotide variant not provided [RCV002995275] Chr11:65662078 [GRCh38]
Chr11:65429549 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.560-11C>G single nucleotide variant not provided [RCV002838258] Chr11:65658833 [GRCh38]
Chr11:65426304 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.678_679del (p.Tyr227fs) microsatellite not provided [RCV002880747] Chr11:65658485..65658486 [GRCh38]
Chr11:65425956..65425957 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.28C>T (p.Pro10Ser) single nucleotide variant not provided [RCV002681201] Chr11:65662185 [GRCh38]
Chr11:65429656 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1158C>T (p.Val386=) single nucleotide variant not provided [RCV003017156] Chr11:65654876 [GRCh38]
Chr11:65422347 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.861G>A (p.Gln287=) single nucleotide variant not provided [RCV002690257] Chr11:65658303 [GRCh38]
Chr11:65425774 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.8-13C>T single nucleotide variant not provided [RCV002696068] Chr11:65662218 [GRCh38]
Chr11:65429689 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.796G>A (p.Val266Met) single nucleotide variant Inborn genetic diseases [RCV002639417]|not provided [RCV002639416] Chr11:65658368 [GRCh38]
Chr11:65425839 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.549_550del (p.Ile183_Phe184insTer) deletion not provided [RCV002866601] Chr11:65659675..65659676 [GRCh38]
Chr11:65427146..65427147 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.875C>G (p.Thr292Arg) single nucleotide variant not provided [RCV002927016] Chr11:65658289 [GRCh38]
Chr11:65425760 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1458C>G (p.Pro486=) single nucleotide variant not provided [RCV002662991] Chr11:65654576 [GRCh38]
Chr11:65422047 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.597G>T (p.Val199=) single nucleotide variant not provided [RCV003039624] Chr11:65658785 [GRCh38]
Chr11:65426256 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.559+9C>T single nucleotide variant not provided [RCV002593331] Chr11:65659657 [GRCh38]
Chr11:65427128 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1056G>A (p.Thr352=) single nucleotide variant not provided [RCV002619783] Chr11:65654978 [GRCh38]
Chr11:65422449 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1563G>A (p.Pro521=) single nucleotide variant not provided [RCV002999181] Chr11:65654471 [GRCh38]
Chr11:65421942 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1005_1019del (p.Arg336_Ser340del) deletion not provided [RCV002659227] Chr11:65655702..65655716 [GRCh38]
Chr11:65423173..65423187 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1027A>C (p.Lys343Gln) single nucleotide variant not provided [RCV003053824] Chr11:65655694 [GRCh38]
Chr11:65423165 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1491T>C (p.Pro497=) single nucleotide variant not provided [RCV002622520] Chr11:65654543 [GRCh38]
Chr11:65422014 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1143G>A (p.Pro381=) single nucleotide variant not provided [RCV002619130] Chr11:65654891 [GRCh38]
Chr11:65422362 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.958+7T>C single nucleotide variant not provided [RCV002570233] Chr11:65655848 [GRCh38]
Chr11:65423319 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1603TCC[1] (p.Ser536del) microsatellite not provided [RCV002975713] Chr11:65654426..65654428 [GRCh38]
Chr11:65421897..65421899 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.817C>T (p.Arg273Trp) single nucleotide variant not provided [RCV002736265] Chr11:65658347 [GRCh38]
Chr11:65425818 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.958+14T>G single nucleotide variant not provided [RCV002868014] Chr11:65655841 [GRCh38]
Chr11:65423312 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.233C>A (p.Thr78Asn) single nucleotide variant not provided [RCV003002810] Chr11:65661789 [GRCh38]
Chr11:65429260 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1033+12del deletion not provided [RCV002570243] Chr11:65655676 [GRCh38]
Chr11:65423147 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.187-7T>C single nucleotide variant not provided [RCV002785410] Chr11:65661842 [GRCh38]
Chr11:65429313 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1368C>T (p.Asn456=) single nucleotide variant not provided [RCV002735025] Chr11:65654666 [GRCh38]
Chr11:65422137 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.923C>T (p.Thr308Ile) single nucleotide variant not provided [RCV002735017] Chr11:65655890 [GRCh38]
Chr11:65423361 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.921G>A (p.Glu307=) single nucleotide variant not provided [RCV002959078] Chr11:65655892 [GRCh38]
Chr11:65423363 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1419G>C (p.Glu473Asp) single nucleotide variant not provided [RCV002666932] Chr11:65654615 [GRCh38]
Chr11:65422086 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.165C>G (p.Thr55=) single nucleotide variant not provided [RCV002917319] Chr11:65661958 [GRCh38]
Chr11:65429429 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.187-9T>G single nucleotide variant not provided [RCV002663732] Chr11:65661844 [GRCh38]
Chr11:65429315 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.298T>A (p.Tyr100Asn) single nucleotide variant not provided [RCV003022231] Chr11:65661724 [GRCh38]
Chr11:65429195 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.34+18C>T single nucleotide variant not provided [RCV002594323] Chr11:65662161 [GRCh38]
Chr11:65429632 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1210G>C (p.Ala404Pro) single nucleotide variant not provided [RCV003024084] Chr11:65654824 [GRCh38]
Chr11:65422295 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1164C>T (p.Pro388=) single nucleotide variant not provided [RCV002574372] Chr11:65654870 [GRCh38]
Chr11:65422341 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.8-12C>G single nucleotide variant not provided [RCV002801376] Chr11:65662217 [GRCh38]
Chr11:65429688 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.174C>T (p.His58=) single nucleotide variant not provided [RCV002700437] Chr11:65661949 [GRCh38]
Chr11:65429420 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.129G>C (p.Ala43=) single nucleotide variant not provided [RCV002876528] Chr11:65661994 [GRCh38]
Chr11:65429465 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1127C>T (p.Ala376Val) single nucleotide variant Inborn genetic diseases [RCV002916458] Chr11:65654907 [GRCh38]
Chr11:65422378 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.889C>T (p.Arg297Trp) single nucleotide variant not provided [RCV002595916] Chr11:65655924 [GRCh38]
Chr11:65423395 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1498A>G (p.Ile500Val) single nucleotide variant not provided [RCV002574548] Chr11:65654536 [GRCh38]
Chr11:65422007 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.34+4A>G single nucleotide variant not provided [RCV002932802] Chr11:65662175 [GRCh38]
Chr11:65429646 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1457C>T (p.Pro486Leu) single nucleotide variant not provided [RCV002593978] Chr11:65654577 [GRCh38]
Chr11:65422048 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1278C>T (p.Pro426=) single nucleotide variant not provided [RCV002631803] Chr11:65654756 [GRCh38]
Chr11:65422227 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.428-18C>T single nucleotide variant not provided [RCV002630066] Chr11:65659815 [GRCh38]
Chr11:65427286 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.336-16G>T single nucleotide variant not provided [RCV003049417] Chr11:65660231 [GRCh38]
Chr11:65427702 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.19C>T (p.Leu7Phe) single nucleotide variant not provided [RCV003048742] Chr11:65662194 [GRCh38]
Chr11:65429665 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1581C>T (p.Leu527=) single nucleotide variant not provided [RCV003049423] Chr11:65654453 [GRCh38]
Chr11:65421924 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1006C>T (p.Arg336Cys) single nucleotide variant not provided [RCV002632071] Chr11:65655715 [GRCh38]
Chr11:65423186 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1166_1184del (p.Gln389fs) deletion not provided [RCV003029970] Chr11:65654850..65654868 [GRCh38]
Chr11:65422321..65422339 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.991A>G (p.Ile331Val) single nucleotide variant not provided [RCV002601261] Chr11:65655730 [GRCh38]
Chr11:65423201 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.321C>T (p.Asp107=) single nucleotide variant not provided [RCV002676517] Chr11:65661701 [GRCh38]
Chr11:65429172 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.370C>T (p.Arg124Trp) single nucleotide variant Inborn genetic diseases [RCV002719310] Chr11:65660181 [GRCh38]
Chr11:65427652 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.664+9C>G single nucleotide variant not provided [RCV002720837] Chr11:65658709 [GRCh38]
Chr11:65426180 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1034-16dup duplication not provided [RCV002630201] Chr11:65655015..65655016 [GRCh38]
Chr11:65422486..65422487 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1034-11C>G single nucleotide variant not provided [RCV002597910] Chr11:65655011 [GRCh38]
Chr11:65422482 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1454C>T (p.Ala485Val) single nucleotide variant not provided [RCV002598429] Chr11:65654580 [GRCh38]
Chr11:65422051 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.959-13C>T single nucleotide variant not provided [RCV002627497] Chr11:65655775 [GRCh38]
Chr11:65423246 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.560-13T>C single nucleotide variant not provided [RCV002650174] Chr11:65658835 [GRCh38]
Chr11:65426306 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.801T>C (p.Arg267=) single nucleotide variant not provided [RCV002578161] Chr11:65658363 [GRCh38]
Chr11:65425834 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1033+13T>G single nucleotide variant not provided [RCV002792081] Chr11:65655675 [GRCh38]
Chr11:65423146 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1284C>T (p.Pro428=) single nucleotide variant not provided [RCV002579371] Chr11:65654750 [GRCh38]
Chr11:65422221 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1515_1516del (p.Ala507fs) deletion not provided [RCV002580198] Chr11:65654518..65654519 [GRCh38]
Chr11:65421989..65421990 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.788A>C (p.Gln263Pro) single nucleotide variant not provided [RCV002670876] Chr11:65658376 [GRCh38]
Chr11:65425847 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.521G>A (p.Arg174His) single nucleotide variant not provided [RCV002601240] Chr11:65659704 [GRCh38]
Chr11:65427175 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1042C>G (p.Pro348Ala) single nucleotide variant not provided [RCV002670919] Chr11:65654992 [GRCh38]
Chr11:65422463 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.64G>C (p.Glu22Gln) single nucleotide variant not provided [RCV002791842] Chr11:65662059 [GRCh38]
Chr11:65429530 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.547A>G (p.Ile183Val) single nucleotide variant not provided [RCV003031780] Chr11:65659678 [GRCh38]
Chr11:65427149 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.502C>G (p.Pro168Ala) single nucleotide variant not provided [RCV002807045] Chr11:65659723 [GRCh38]
Chr11:65427194 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1044C>T (p.Pro348=) single nucleotide variant not provided [RCV002812046] Chr11:65654990 [GRCh38]
Chr11:65422461 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.918T>C (p.Tyr306=) single nucleotide variant not provided [RCV003065528] Chr11:65655895 [GRCh38]
Chr11:65423366 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.559+16G>C single nucleotide variant not provided [RCV002583801] Chr11:65659650 [GRCh38]
Chr11:65427121 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.29C>T (p.Pro10Leu) single nucleotide variant not provided [RCV002583597] Chr11:65662184 [GRCh38]
Chr11:65429655 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.324C>A (p.Arg108=) single nucleotide variant not provided [RCV002725692] Chr11:65661698 [GRCh38]
Chr11:65429169 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1441G>T (p.Gly481Cys) single nucleotide variant not provided [RCV002814287] Chr11:65654593 [GRCh38]
Chr11:65422064 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1243C>T (p.Pro415Ser) single nucleotide variant not provided [RCV002586833] Chr11:65654791 [GRCh38]
Chr11:65422262 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1618A>G (p.Met540Val) single nucleotide variant not provided [RCV002585991] Chr11:65654416 [GRCh38]
Chr11:65421887 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.448G>A (p.Gly150Arg) single nucleotide variant not provided [RCV002608779] Chr11:65659777 [GRCh38]
Chr11:65427248 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.428-17G>A single nucleotide variant not provided [RCV002608797] Chr11:65659814 [GRCh38]
Chr11:65427285 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1154A>G (p.Gln385Arg) single nucleotide variant not provided [RCV002583844] Chr11:65654880 [GRCh38]
Chr11:65422351 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1304C>T (p.Thr435Met) single nucleotide variant not provided [RCV002635008] Chr11:65654730 [GRCh38]
Chr11:65422201 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1207C>G (p.Leu403Val) single nucleotide variant not provided [RCV002584332] Chr11:65654827 [GRCh38]
Chr11:65422298 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1607C>G (p.Ser536Cys) single nucleotide variant Inborn genetic diseases [RCV003308878] Chr11:65654427 [GRCh38]
Chr11:65421898 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1541C>G (p.Ala514Gly) single nucleotide variant not provided [RCV003322003] Chr11:65654493 [GRCh38]
Chr11:65421964 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1612G>A (p.Ala538Thr) single nucleotide variant Inborn genetic diseases [RCV003357145]|not provided [RCV003699074] Chr11:65654422 [GRCh38]
Chr11:65421893 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.496C>T (p.Arg166Trp) single nucleotide variant Inborn genetic diseases [RCV003367194] Chr11:65659729 [GRCh38]
Chr11:65427200 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.560-19C>T single nucleotide variant not provided [RCV003826734] Chr11:65658841 [GRCh38]
Chr11:65426312 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.519C>G (p.Leu173=) single nucleotide variant not provided [RCV003873453] Chr11:65659706 [GRCh38]
Chr11:65427177 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1113G>A (p.Gly371=) single nucleotide variant not provided [RCV003691030] Chr11:65654921 [GRCh38]
Chr11:65422392 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1552C>T (p.Leu518=) single nucleotide variant not provided [RCV003874426] Chr11:65654482 [GRCh38]
Chr11:65421953 [GRCh37]
Chr11:11q13.1
likely benign
GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 copy number gain not provided [RCV003484842] Chr11:59923608..76272324 [GRCh37]
Chr11:11q12.2-13.5
pathogenic
NM_021975.4(RELA):c.665-10_665-9insAC insertion not provided [RCV003691066] Chr11:65658508..65658509 [GRCh38]
Chr11:65425979..65425980 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1035A>G (p.Ala345=) single nucleotide variant not provided [RCV003409298] Chr11:65654999 [GRCh38]
Chr11:65422470 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.608_609del (p.Ser203fs) microsatellite not provided [RCV003695369] Chr11:65658773..65658774 [GRCh38]
Chr11:65426244..65426245 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1242C>T (p.Ala414=) single nucleotide variant not provided [RCV003831469] Chr11:65654792 [GRCh38]
Chr11:65422263 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1300G>T (p.Gly434Ter) single nucleotide variant not provided [RCV003578777] Chr11:65654734 [GRCh38]
Chr11:65422205 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1033+77C>T single nucleotide variant not specified [RCV003488880] Chr11:65655611 [GRCh38]
Chr11:65423082 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1407C>T (p.Val469=) single nucleotide variant not provided [RCV003849089] Chr11:65654627 [GRCh38]
Chr11:65422098 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1416C>G (p.Ser472=) single nucleotide variant not provided [RCV003662201] Chr11:65654618 [GRCh38]
Chr11:65422089 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.336-3C>T single nucleotide variant not provided [RCV003828967] Chr11:65660218 [GRCh38]
Chr11:65427689 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.93C>T (p.Gly31=) single nucleotide variant not provided [RCV003696791] Chr11:65662030 [GRCh38]
Chr11:65429501 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1167G>A (p.Gln389=) single nucleotide variant not provided [RCV003573394] Chr11:65654867 [GRCh38]
Chr11:65422338 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.933C>T (p.Ser311=) single nucleotide variant not provided [RCV003878235] Chr11:65655880 [GRCh38]
Chr11:65423351 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.513G>T (p.Arg171Ser) single nucleotide variant not provided [RCV003694952] Chr11:65659712 [GRCh38]
Chr11:65427183 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.996T>C (p.Ala332=) single nucleotide variant not provided [RCV003662776] Chr11:65655725 [GRCh38]
Chr11:65423196 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.813G>A (p.Gln271=) single nucleotide variant not provided [RCV003690414] Chr11:65658351 [GRCh38]
Chr11:65425822 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1220del (p.Pro407fs) deletion not provided [RCV003691480] Chr11:65654814 [GRCh38]
Chr11:65422285 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1114C>T (p.Gln372Ter) single nucleotide variant Mucocutaneous ulceration, chronic [RCV003494566]|not provided [RCV003575118] Chr11:65654920 [GRCh38]
Chr11:65422391 [GRCh37]
Chr11:11q13.1
pathogenic|uncertain significance
NM_021975.4(RELA):c.959-9G>A single nucleotide variant not provided [RCV003572151] Chr11:65655771 [GRCh38]
Chr11:65423242 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.428-78C>T single nucleotide variant not specified [RCV003489150] Chr11:65659875 [GRCh38]
Chr11:65427346 [GRCh37]
Chr11:11q13.1
benign
NM_021975.4(RELA):c.1485G>C (p.Glu495Asp) single nucleotide variant not provided [RCV003713428] Chr11:65654549 [GRCh38]
Chr11:65422020 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.878-18_878-16del deletion not provided [RCV003660563] Chr11:65655951..65655953 [GRCh38]
Chr11:65423422..65423424 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1525A>C (p.Arg509=) single nucleotide variant not provided [RCV003660230] Chr11:65654509 [GRCh38]
Chr11:65421980 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.789G>T (p.Gln263His) single nucleotide variant not provided [RCV003544593] Chr11:65658375 [GRCh38]
Chr11:65425846 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.29del (p.Pro10fs) deletion not provided [RCV003494355] Chr11:65662184 [GRCh38]
Chr11:65429655 [GRCh37]
Chr11:11q13.1
likely pathogenic
NM_021975.4(RELA):c.560-16G>A single nucleotide variant not provided [RCV003660231] Chr11:65658838 [GRCh38]
Chr11:65426309 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.47C>T (p.Ala16Val) single nucleotide variant not provided [RCV003663236] Chr11:65662076 [GRCh38]
Chr11:65429547 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.560-16G>C single nucleotide variant not provided [RCV003546233] Chr11:65658838 [GRCh38]
Chr11:65426309 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.878-3C>T single nucleotide variant not provided [RCV003715876] Chr11:65655938 [GRCh38]
Chr11:65423409 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.560-20C>T single nucleotide variant not provided [RCV003815193] Chr11:65658842 [GRCh38]
Chr11:65426313 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1250C>T (p.Pro417Leu) single nucleotide variant not provided [RCV003665408] Chr11:65654784 [GRCh38]
Chr11:65422255 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.965C>T (p.Thr322Ile) single nucleotide variant not provided [RCV003838321] Chr11:65655756 [GRCh38]
Chr11:65423227 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.459C>T (p.Asp153=) single nucleotide variant not provided [RCV003725069] Chr11:65659766 [GRCh38]
Chr11:65427237 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1307T>C (p.Leu436Pro) single nucleotide variant not provided [RCV003673184] Chr11:65654727 [GRCh38]
Chr11:65422198 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.336-12G>C single nucleotide variant not provided [RCV003839928] Chr11:65660227 [GRCh38]
Chr11:65427698 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1061C>T (p.Ser354Phe) single nucleotide variant not provided [RCV003668182] Chr11:65654973 [GRCh38]
Chr11:65422444 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1135T>C (p.Leu379=) single nucleotide variant not provided [RCV003703028] Chr11:65654899 [GRCh38]
Chr11:65422370 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1210G>A (p.Ala404Thr) single nucleotide variant not provided [RCV003812130] Chr11:65654824 [GRCh38]
Chr11:65422295 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1325A>C (p.Gln442Pro) single nucleotide variant not provided [RCV003724485] Chr11:65654709 [GRCh38]
Chr11:65422180 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1645A>T (p.Ile549Phe) single nucleotide variant not provided [RCV003701815] Chr11:65654389 [GRCh38]
Chr11:65421860 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1034-13C>G single nucleotide variant not provided [RCV003671740] Chr11:65655013 [GRCh38]
Chr11:65422484 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.691C>A (p.Pro231Thr) single nucleotide variant not provided [RCV003837584] Chr11:65658473 [GRCh38]
Chr11:65425944 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.964A>G (p.Thr322Ala) single nucleotide variant not provided [RCV003836799] Chr11:65655757 [GRCh38]
Chr11:65423228 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1644G>A (p.Gln548=) single nucleotide variant not provided [RCV003832551] Chr11:65654390 [GRCh38]
Chr11:65421861 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.222C>T (p.Ile74=) single nucleotide variant not provided [RCV003680961] Chr11:65661800 [GRCh38]
Chr11:65429271 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.560-17T>C single nucleotide variant not provided [RCV003710247] Chr11:65658839 [GRCh38]
Chr11:65426310 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1070C>T (p.Thr357Ile) single nucleotide variant not provided [RCV003709136] Chr11:65654964 [GRCh38]
Chr11:65422435 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.878-7T>C single nucleotide variant not provided [RCV003564882] Chr11:65655942 [GRCh38]
Chr11:65423413 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.829G>A (p.Asp277Asn) single nucleotide variant not provided [RCV003677130] Chr11:65658335 [GRCh38]
Chr11:65425806 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.241C>T (p.Pro81Ser) single nucleotide variant not provided [RCV003731777] Chr11:65661781 [GRCh38]
Chr11:65429252 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1092C>T (p.Pro364=) single nucleotide variant not provided [RCV003708112] Chr11:65654942 [GRCh38]
Chr11:65422413 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.355C>T (p.Gln119Ter) single nucleotide variant not provided [RCV003708989] Chr11:65660196 [GRCh38]
Chr11:65427667 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1063C>G (p.Leu355Val) single nucleotide variant not provided [RCV003682157] Chr11:65654971 [GRCh38]
Chr11:65422442 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1034-4C>T single nucleotide variant not provided [RCV003822577] Chr11:65655004 [GRCh38]
Chr11:65422475 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.507A>C (p.Ser169=) single nucleotide variant not provided [RCV003676631] Chr11:65659718 [GRCh38]
Chr11:65427189 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1289A>G (p.Gln430Arg) single nucleotide variant not provided [RCV003728856] Chr11:65654745 [GRCh38]
Chr11:65422216 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1609A>G (p.Ile537Val) single nucleotide variant not provided [RCV003736260] Chr11:65654425 [GRCh38]
Chr11:65421896 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1029G>C (p.Lys343Asn) single nucleotide variant not provided [RCV003681490] Chr11:65655692 [GRCh38]
Chr11:65423163 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.491C>T (p.Thr164Ile) single nucleotide variant not provided [RCV003860219] Chr11:65659734 [GRCh38]
Chr11:65427205 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1046A>G (p.Tyr349Cys) single nucleotide variant not provided [RCV003563164] Chr11:65654988 [GRCh38]
Chr11:65422459 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.286C>A (p.Arg96=) single nucleotide variant not provided [RCV003842579] Chr11:65661736 [GRCh38]
Chr11:65429207 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.877+12G>C single nucleotide variant not provided [RCV003708981] Chr11:65658275 [GRCh38]
Chr11:65425746 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1031C>T (p.Pro344Leu) single nucleotide variant not provided [RCV003711060] Chr11:65655690 [GRCh38]
Chr11:65423161 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.335+19A>C single nucleotide variant not provided [RCV003678400] Chr11:65661668 [GRCh38]
Chr11:65429139 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1217C>T (p.Ala406Val) single nucleotide variant not provided [RCV003731433] Chr11:65654817 [GRCh38]
Chr11:65422288 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1163C>T (p.Pro388Leu) single nucleotide variant not provided [RCV003733396] Chr11:65654871 [GRCh38]
Chr11:65422342 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.346C>T (p.Leu116=) single nucleotide variant not provided [RCV003684149] Chr11:65660205 [GRCh38]
Chr11:65427676 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1420_1428del (p.Phe474_Gln476del) deletion not provided [RCV003565309] Chr11:65654606..65654614 [GRCh38]
Chr11:65422077..65422085 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1574A>G (p.Asn525Ser) single nucleotide variant not provided [RCV003733948] Chr11:65654460 [GRCh38]
Chr11:65421931 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.428-18C>G single nucleotide variant not provided [RCV003868158] Chr11:65659815 [GRCh38]
Chr11:65427286 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.877+12G>A single nucleotide variant not provided [RCV003677709] Chr11:65658275 [GRCh38]
Chr11:65425746 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.1596A>T (p.Glu532Asp) single nucleotide variant not provided [RCV003737840] Chr11:65654438 [GRCh38]
Chr11:65421909 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.522C>T (p.Arg174=) single nucleotide variant not provided [RCV003870013] Chr11:65659703 [GRCh38]
Chr11:65427174 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.688G>A (p.Gly230Arg) single nucleotide variant not provided [RCV003730805] Chr11:65658476 [GRCh38]
Chr11:65425947 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.877+12G>T single nucleotide variant not provided [RCV003683772] Chr11:65658275 [GRCh38]
Chr11:65425746 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.48C>T (p.Ala16=) single nucleotide variant not provided [RCV003719775] Chr11:65662075 [GRCh38]
Chr11:65429546 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.468T>C (p.Ala156=) single nucleotide variant not provided [RCV003859331] Chr11:65659757 [GRCh38]
Chr11:65427228 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.678G>A (p.Val226=) single nucleotide variant not provided [RCV003865013] Chr11:65658486 [GRCh38]
Chr11:65425957 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.917dup (p.Tyr306Ter) duplication not provided [RCV003863074] Chr11:65655895..65655896 [GRCh38]
Chr11:65423366..65423367 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1608C>T (p.Ser536=) single nucleotide variant not provided [RCV003678648] Chr11:65654426 [GRCh38]
Chr11:65421897 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.75G>A (p.Glu25=) single nucleotide variant not provided [RCV003678866] Chr11:65662048 [GRCh38]
Chr11:65429519 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.776A>T (p.Asp259Val) single nucleotide variant not provided [RCV003853473] Chr11:65658388 [GRCh38]
Chr11:65425859 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.495G>A (p.Val165=) single nucleotide variant not provided [RCV003845569] Chr11:65659730 [GRCh38]
Chr11:65427201 [GRCh37]
Chr11:11q13.1
benign
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3
likely pathogenic
NM_021975.4(RELA):c.442C>T (p.Gln148Ter) single nucleotide variant not provided [RCV003681959] Chr11:65659783 [GRCh38]
Chr11:65427254 [GRCh37]
Chr11:11q13.1
pathogenic
NM_021975.4(RELA):c.1378C>G (p.Pro460Ala) single nucleotide variant not provided [RCV003863897] Chr11:65654656 [GRCh38]
Chr11:65422127 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.397C>T (p.Arg133Cys) single nucleotide variant not provided [RCV003711377] Chr11:65660154 [GRCh38]
Chr11:65427625 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1316C>A (p.Ala439Asp) single nucleotide variant not provided [RCV003682736] Chr11:65654718 [GRCh38]
Chr11:65422189 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1274C>T (p.Ala425Val) single nucleotide variant not provided [RCV003682730] Chr11:65654760 [GRCh38]
Chr11:65422231 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1626C>A (p.Phe542Leu) single nucleotide variant not provided [RCV003682822] Chr11:65654408 [GRCh38]
Chr11:65421879 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.559+10G>A single nucleotide variant not provided [RCV003681332] Chr11:65659656 [GRCh38]
Chr11:65427127 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.878-9C>T single nucleotide variant not provided [RCV003842508] Chr11:65655944 [GRCh38]
Chr11:65423415 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.705C>A (p.Ala235=) single nucleotide variant not provided [RCV003556582] Chr11:65658459 [GRCh38]
Chr11:65425930 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.622G>A (p.Gly208Ser) single nucleotide variant not provided [RCV003675051] Chr11:65658760 [GRCh38]
Chr11:65426231 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.1184C>G (p.Pro395Arg) single nucleotide variant not provided [RCV003553619] Chr11:65654850 [GRCh38]
Chr11:65422321 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.621C>T (p.Leu207=) single nucleotide variant not provided [RCV003846969] Chr11:65658761 [GRCh38]
Chr11:65426232 [GRCh37]
Chr11:11q13.1
likely benign
NM_021975.4(RELA):c.401T>C (p.Ile134Thr) single nucleotide variant not provided [RCV003566922] Chr11:65660150 [GRCh38]
Chr11:65427621 [GRCh37]
Chr11:11q13.1
uncertain significance
NM_021975.4(RELA):c.262_272del (p.His88fs) deletion RELA-related condition [RCV003894623] Chr11:65661750..65661760 [GRCh38]
Chr11:65429221..65429231 [GRCh37]
Chr11:11q13.1
likely pathogenic
NM_021975.4(RELA):c.1524G>C (p.Gln508His) single nucleotide variant RELA-related condition [RCV003894060] Chr11:65654510 [GRCh38]
Chr11:65421981 [GRCh37]
Chr11:11q13.1
likely benign
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR520Chsa-miR-520c-3pOncomiRDBexternal_infoNANA22158050
MIR373hsa-miR-373-3pOncomiRDBexternal_infoNANA22158050
MIR124-2hsa-miR-124-3pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//Microarray;Functional MTI15685193

Predicted Target Of
Summary Value
Count of predictions:8908
Count of miRNA genes:1282
Interacting mature miRNAs:1667
Transcripts:ENST00000308639, ENST00000406246, ENST00000525301, ENST00000525658, ENST00000525693, ENST00000525858, ENST00000526257, ENST00000526283, ENST00000526738, ENST00000527074, ENST00000527749, ENST00000527874, ENST00000527909, ENST00000529330, ENST00000529389, ENST00000531238, ENST00000531484, ENST00000532776, ENST00000532879, ENST00000532999, ENST00000533187, ENST00000533546, ENST00000534283, ENST00000534305, ENST00000534558
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-83845  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,431,450 - 65,431,767UniSTSGRCh37
Build 361165,188,026 - 65,188,343RGDNCBI36
Celera1162,758,131 - 62,758,448RGD
Cytogenetic Map11q13UniSTS
HuRef1161,758,443 - 61,758,760UniSTS
TNG Radiation Hybrid Map1128999.0UniSTS
UniSTS:144339  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,425,879 - 65,425,966UniSTSGRCh37
Build 361165,182,455 - 65,182,542RGDNCBI36
Celera1162,752,581 - 62,752,668RGD
HuRef1161,752,872 - 61,752,959UniSTS
RH44538  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,421,234 - 65,421,357UniSTSGRCh37
Build 361165,177,810 - 65,177,933RGDNCBI36
Celera1162,747,939 - 62,748,062RGD
Cytogenetic Map11q13UniSTS
HuRef1161,748,223 - 61,748,346UniSTS
GeneMap99-GB4 RH Map11240.12UniSTS
NCBI RH Map11573.2UniSTS
NFKB3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371165,421,154 - 65,421,781UniSTSGRCh37
Build 361165,177,730 - 65,178,357RGDNCBI36
Celera1162,747,859 - 62,748,486RGD
Cytogenetic Map11q13UniSTS
HuRef1161,748,143 - 61,748,770UniSTS
GeneMap99-GB4 RH Map11238.23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2437 2909 1717 617 1934 458 4355 2133 3403 406 1459 1612 175 1 1204 2787 5 2
Low 2 82 9 7 17 7 2 64 331 13 1 1 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001145138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001243984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001243985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK303262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY455868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM916512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU633061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA020095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF548091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT584490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M62399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MN508965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U33838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000308639   ⟹   ENSP00000311508
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,653,602 - 65,663,090 (-)Ensembl
RefSeq Acc Id: ENST00000406246   ⟹   ENSP00000384273
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,653,601 - 65,662,916 (-)Ensembl
RefSeq Acc Id: ENST00000525301
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,660,156 - 65,662,918 (-)Ensembl
RefSeq Acc Id: ENST00000525658   ⟹   ENSP00000434008
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,658,287 - 65,662,915 (-)Ensembl
RefSeq Acc Id: ENST00000525693   ⟹   ENSP00000432537
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,653,601 - 65,662,895 (-)Ensembl
RefSeq Acc Id: ENST00000525858
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,661,408 - 65,662,972 (-)Ensembl
RefSeq Acc Id: ENST00000526257   ⟹   ENSP00000431304
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,655,707 - 65,659,743 (-)Ensembl
RefSeq Acc Id: ENST00000526283   ⟹   ENSP00000435290
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,653,602 - 65,662,895 (-)Ensembl
RefSeq Acc Id: ENST00000526738
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,658,602 - 65,660,792 (-)Ensembl
RefSeq Acc Id: ENST00000527074
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,660,052 - 65,662,918 (-)Ensembl
RefSeq Acc Id: ENST00000527749   ⟹   ENSP00000436545
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,658,732 - 65,662,792 (-)Ensembl
RefSeq Acc Id: ENST00000527874   ⟹   ENSP00000435531
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,660,189 - 65,662,428 (-)Ensembl
RefSeq Acc Id: ENST00000527909   ⟹   ENSP00000432922
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,658,718 - 65,662,908 (-)Ensembl
RefSeq Acc Id: ENST00000529330
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,658,769 - 65,660,162 (-)Ensembl
RefSeq Acc Id: ENST00000529389   ⟹   ENSP00000437137
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,655,857 - 65,662,960 (-)Ensembl
RefSeq Acc Id: ENST00000531238   ⟹   ENSP00000434745
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,659,744 - 65,662,908 (-)Ensembl
RefSeq Acc Id: ENST00000531484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,653,967 - 65,662,915 (-)Ensembl
RefSeq Acc Id: ENST00000532776
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,661,633 - 65,662,944 (-)Ensembl
RefSeq Acc Id: ENST00000532879   ⟹   ENSP00000431153
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,659,682 - 65,662,915 (-)Ensembl
RefSeq Acc Id: ENST00000532999   ⟹   ENSP00000433526
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,654,812 - 65,662,918 (-)Ensembl
RefSeq Acc Id: ENST00000533187   ⟹   ENSP00000434098
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,660,172 - 65,662,793 (-)Ensembl
RefSeq Acc Id: ENST00000533546   ⟹   ENSP00000433144
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,658,430 - 65,662,908 (-)Ensembl
RefSeq Acc Id: ENST00000534283   ⟹   ENSP00000433616
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,661,943 - 65,662,780 (-)Ensembl
RefSeq Acc Id: ENST00000534305
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,661,511 - 65,662,897 (-)Ensembl
RefSeq Acc Id: ENST00000534558   ⟹   ENSP00000434372
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,658,730 - 65,662,899 (-)Ensembl
RefSeq Acc Id: ENST00000612991   ⟹   ENSP00000483705
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,653,599 - 65,662,972 (-)Ensembl
RefSeq Acc Id: ENST00000615805   ⟹   ENSP00000479572
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1165,653,597 - 65,662,972 (-)Ensembl
RefSeq Acc Id: NM_001145138   ⟹   NP_001138610
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
GRCh371165,421,067 - 65,430,443 (-)ENTREZGENE
HuRef1161,748,056 - 61,757,436 (-)ENTREZGENE
CHM1_11165,305,002 - 65,314,374 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001243984   ⟹   NP_001230913
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
GRCh371165,421,067 - 65,430,443 (-)NCBI
HuRef1161,748,056 - 61,757,436 (-)NCBI
CHM1_11165,305,002 - 65,314,374 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001243985   ⟹   NP_001230914
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
GRCh371165,421,067 - 65,430,443 (-)NCBI
HuRef1161,748,056 - 61,757,436 (-)NCBI
CHM1_11165,305,002 - 65,314,374 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001404657   ⟹   NP_001391586
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
RefSeq Acc Id: NM_001404658   ⟹   NP_001391587
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
RefSeq Acc Id: NM_001404659   ⟹   NP_001391588
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
RefSeq Acc Id: NM_001404660   ⟹   NP_001391589
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
RefSeq Acc Id: NM_001404661   ⟹   NP_001391590
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
RefSeq Acc Id: NM_001404662   ⟹   NP_001391591
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,663,857 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,658,027 (-)NCBI
RefSeq Acc Id: NM_001404663   ⟹   NP_001391592
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
RefSeq Acc Id: NM_021975   ⟹   NP_068810
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,916 (-)NCBI
GRCh371165,421,067 - 65,430,443 (-)ENTREZGENE
Build 361165,178,393 - 65,186,951 (-)NCBI Archive
HuRef1161,748,056 - 61,757,436 (-)ENTREZGENE
CHM1_11165,305,002 - 65,314,374 (-)NCBI
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047427392   ⟹   XP_047283348
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,653,601 - 65,662,577 (-)NCBI
RefSeq Acc Id: XM_054369602   ⟹   XP_054225577
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01165,647,771 - 65,656,573 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001138610 (Get FASTA)   NCBI Sequence Viewer  
  NP_001230913 (Get FASTA)   NCBI Sequence Viewer  
  NP_001230914 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391586 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391587 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391588 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391589 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391590 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391591 (Get FASTA)   NCBI Sequence Viewer  
  NP_001391592 (Get FASTA)   NCBI Sequence Viewer  
  NP_068810 (Get FASTA)   NCBI Sequence Viewer  
  XP_047283348 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225577 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA20946 (Get FASTA)   NCBI Sequence Viewer  
  AAA36408 (Get FASTA)   NCBI Sequence Viewer  
  AAA92888 (Get FASTA)   NCBI Sequence Viewer  
  AAB48487 (Get FASTA)   NCBI Sequence Viewer  
  AAH11603 (Get FASTA)   NCBI Sequence Viewer  
  AAH14095 (Get FASTA)   NCBI Sequence Viewer  
  AAH33522 (Get FASTA)   NCBI Sequence Viewer  
  AAI10831 (Get FASTA)   NCBI Sequence Viewer  
  AAR13863 (Get FASTA)   NCBI Sequence Viewer  
  BAG64344 (Get FASTA)   NCBI Sequence Viewer  
  CAA80524 (Get FASTA)   NCBI Sequence Viewer  
  CCO13802 (Get FASTA)   NCBI Sequence Viewer  
  EAW74424 (Get FASTA)   NCBI Sequence Viewer  
  EAW74425 (Get FASTA)   NCBI Sequence Viewer  
  EAW74426 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000311508
  ENSP00000311508.9
  ENSP00000384273
  ENSP00000384273.3
  ENSP00000431153.1
  ENSP00000431304.1
  ENSP00000432537.1
  ENSP00000433144.1
  ENSP00000433526.1
  ENSP00000433616.1
  ENSP00000434008.1
  ENSP00000434098.1
  ENSP00000434372.1
  ENSP00000434745.1
  ENSP00000435290.1
  ENSP00000435531.1
  ENSP00000436545.1
  ENSP00000437137.1
  ENSP00000483705
  ENSP00000483705.1
GenBank Protein Q04206 (Get FASTA)   NCBI Sequence Viewer  
  QOP57501 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001138610   ⟸   NM_001145138
- Peptide Label: isoform 2
- UniProtKB: Q04206 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_068810   ⟸   NM_021975
- Peptide Label: isoform 1
- UniProtKB: Q6GTV1 (UniProtKB/Swiss-Prot),   Q6SLK1 (UniProtKB/Swiss-Prot),   Q04206 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001230913   ⟸   NM_001243984
- Peptide Label: isoform 3
- UniProtKB: Q04206 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001230914   ⟸   NM_001243985
- Peptide Label: isoform 4
- UniProtKB: A0A087X0W8 (UniProtKB/TrEMBL),   E9PKH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000311508   ⟸   ENST00000308639
RefSeq Acc Id: ENSP00000434745   ⟸   ENST00000531238
RefSeq Acc Id: ENSP00000433526   ⟸   ENST00000532999
RefSeq Acc Id: ENSP00000431153   ⟸   ENST00000532879
RefSeq Acc Id: ENSP00000434098   ⟸   ENST00000533187
RefSeq Acc Id: ENSP00000433144   ⟸   ENST00000533546
RefSeq Acc Id: ENSP00000433616   ⟸   ENST00000534283
RefSeq Acc Id: ENSP00000434372   ⟸   ENST00000534558
RefSeq Acc Id: ENSP00000483705   ⟸   ENST00000612991
RefSeq Acc Id: ENSP00000479572   ⟸   ENST00000615805
RefSeq Acc Id: ENSP00000384273   ⟸   ENST00000406246
RefSeq Acc Id: ENSP00000432537   ⟸   ENST00000525693
RefSeq Acc Id: ENSP00000434008   ⟸   ENST00000525658
RefSeq Acc Id: ENSP00000431304   ⟸   ENST00000526257
RefSeq Acc Id: ENSP00000435290   ⟸   ENST00000526283
RefSeq Acc Id: ENSP00000432922   ⟸   ENST00000527909
RefSeq Acc Id: ENSP00000435531   ⟸   ENST00000527874
RefSeq Acc Id: ENSP00000436545   ⟸   ENST00000527749
RefSeq Acc Id: ENSP00000437137   ⟸   ENST00000529389
RefSeq Acc Id: XP_047283348   ⟸   XM_047427392
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001391591   ⟸   NM_001404662
- Peptide Label: isoform p65 iso 5
RefSeq Acc Id: NP_001391587   ⟸   NM_001404658
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001391590   ⟸   NM_001404661
- Peptide Label: isoform 9
RefSeq Acc Id: NP_001391589   ⟸   NM_001404660
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001391588   ⟸   NM_001404659
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001391586   ⟸   NM_001404657
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001391592   ⟸   NM_001404663
- Peptide Label: isoform p65 iso 5
RefSeq Acc Id: XP_054225577   ⟸   XM_054369602
- Peptide Label: isoform X1
Protein Domains
RHD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q04206-F1-model_v2 AlphaFold Q04206 1-551 view protein structure

Promoters
RGD ID:6810121
Promoter ID:HG_ACW:12663
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:RELA.SAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 361165,182,231 - 65,182,731 (-)MPROMDB
RGD ID:6789312
Promoter ID:HG_KWN:13353
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Lymphoblastoid
Transcripts:UC009YQS.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361165,183,671 - 65,184,422 (-)MPROMDB
RGD ID:6814501
Promoter ID:HG_XEF:1458
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:NM_001001211,   NM_001001839,   NM_001087579,   NM_001114281,   NM_199267,   NM_205129
Position:
Human AssemblyChrPosition (strand)Source
Build 361165,185,716 - 65,186,377 (-)MPROMDB
RGD ID:6850620
Promoter ID:EP73104
Type:multiple initiation site
Name:HS_RELA
Description:V-rel reticuloendotheliosis viral oncogene homolog A, nuclearfactor of kappa light polypeptide gene enhancer in B-cells 3, p65(avian).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361165,186,954 - 65,187,014EPD
RGD ID:6789311
Promoter ID:HG_KWN:13354
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000308546,   NM_001145138,   NM_021975,   UC001OFE.1,   UC001OFF.1,   UC009YQR.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361165,186,956 - 65,187,877 (-)MPROMDB
RGD ID:7221045
Promoter ID:EPDNEW_H16268
Type:initiation region
Name:RELA_1
Description:RELA proto-oncogene, NF-kB subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381165,662,916 - 65,662,976EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9955 AgrOrtholog
COSMIC RELA COSMIC
Ensembl Genes ENSG00000173039 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000308639 ENTREZGENE
  ENST00000308639.13 UniProtKB/Swiss-Prot
  ENST00000406246 ENTREZGENE
  ENST00000406246.8 UniProtKB/Swiss-Prot
  ENST00000525658.5 UniProtKB/TrEMBL
  ENST00000525693.5 UniProtKB/TrEMBL
  ENST00000526257.1 UniProtKB/TrEMBL
  ENST00000526283.6 UniProtKB/TrEMBL
  ENST00000527749.5 UniProtKB/TrEMBL
  ENST00000527874.1 UniProtKB/TrEMBL
  ENST00000529389.5 UniProtKB/TrEMBL
  ENST00000531238.1 UniProtKB/TrEMBL
  ENST00000531484 ENTREZGENE
  ENST00000532879.5 UniProtKB/TrEMBL
  ENST00000532999.5 UniProtKB/TrEMBL
  ENST00000533187.5 UniProtKB/TrEMBL
  ENST00000533546.5 UniProtKB/TrEMBL
  ENST00000534283.1 UniProtKB/TrEMBL
  ENST00000534558.5 UniProtKB/TrEMBL
  ENST00000612991 ENTREZGENE
  ENST00000612991.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.340 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000173039 GTEx
HGNC ID HGNC:9955 ENTREZGENE
Human Proteome Map RELA Human Proteome Map
InterPro Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPT_NFkappaB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NFkB/Dor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RelA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHD_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHD_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHD_DNA_bind_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHD_DNA_bind_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5970 UniProtKB/Swiss-Prot
NCBI Gene 5970 ENTREZGENE
OMIM 164014 OMIM
PANTHER PTHR24169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24169:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RHD_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHD_DNA_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA296 PharmGKB
PRINTS NFKBTNSCPFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE REL_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  REL_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087X0W8 ENTREZGENE, UniProtKB/TrEMBL
  E9PI38_HUMAN UniProtKB/TrEMBL
  E9PJR1_HUMAN UniProtKB/TrEMBL
  E9PJZ9_HUMAN UniProtKB/TrEMBL
  E9PKH5 ENTREZGENE, UniProtKB/TrEMBL
  E9PKV4_HUMAN UniProtKB/TrEMBL
  E9PM47_HUMAN UniProtKB/TrEMBL
  E9PMD5_HUMAN UniProtKB/TrEMBL
  E9PNK5_HUMAN UniProtKB/TrEMBL
  E9PNV4_HUMAN UniProtKB/TrEMBL
  E9PQS6_HUMAN UniProtKB/TrEMBL
  E9PRX2_HUMAN UniProtKB/TrEMBL
  E9PSE4_HUMAN UniProtKB/TrEMBL
  H0YCB4_HUMAN UniProtKB/TrEMBL
  L0R6N5_HUMAN UniProtKB/TrEMBL
  Q04206 ENTREZGENE
  Q2TAM5_HUMAN UniProtKB/TrEMBL
  Q6GTV1 ENTREZGENE
  Q6SLK1 ENTREZGENE
  Q96CP1_HUMAN UniProtKB/TrEMBL
  Q96F54_HUMAN UniProtKB/TrEMBL
  TF65_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q6GTV1 UniProtKB/Swiss-Prot
  Q6SLK1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-03 RELA  RELA proto-oncogene, NF-kB subunit    v-rel avian reticuloendotheliosis viral oncogene homolog A  Symbol and/or name change 5135510 APPROVED
2013-07-16 RELA  v-rel avian reticuloendotheliosis viral oncogene homolog A    v-rel reticuloendotheliosis viral oncogene homolog A (avian)  Symbol and/or name change 5135510 APPROVED