Gene: DNAJA3 (DnaJ (Hsp40) homolog, subfamily A, member 3)  Homo sapiens
Symbol: DNAJA3
Name: DnaJ (Hsp40) homolog, subfamily A, member 3
Description: This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dnaJ homolog subfamily A member 3, mitochondrial; dnaJ protein Tid-1; FLJ45758; HCA57; hepatocellular carcinoma-associated antigen 57; hTid-1; hTID-1; OTTHUMP00000159844; TID1; tumorous imaginal discs homolog; tumorous imaginal discs protein Tid56 homolog
Orthologs: Mus musculus : Dnaja3 (DnaJ (Hsp40) homolog, subfamily A, member 3)  MGI
Rattus norvegicus : Dnaja3 (DnaJ (Hsp40) homolog, subfamily A, member 3)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1164,412,110 - 4,443,070+NCBI
Human Genome Assembly HuRef164,443,030 - 4,474,077+NCBI
Human Genome Assembly GRCh37164,475,806 - 4,506,776+NCBI
Human Genome Assembly Build 36164,415,883 - 4,446,777+NCBI
Human Cytogenetic Map16p13.3 NCBI
Human Genome Assembly164,415,882 - 4,446,774 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)

Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
  
More on DNAJA3
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1315195
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE



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