Gene: ATF2 (activating transcription factor 2)  Homo sapiens
Symbol: ATF2
Name: activating transcription factor 2
Description: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activating transcription factor 2 splice variant ATF2-var2; cAMP response element-binding protein CRE-BP1; cAMP responsive element binding protein 2, formerly; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE-BP1; CREB-2; CREB2; cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-responsive element-binding protein 2; HB16; MGC111558; OTTHUMP00000163262; OTTHUMP00000205344; OTTHUMP00000205345; OTTHUMP00000205347; OTTHUMP00000205348; OTTHUMP00000205350; OTTHUMP00000205352; OTTHUMP00000205353; OTTHUMP00000205354; ratf2; TREB7
Orthologs: Mus musculus : Atf2 (activating transcription factor 2)  MGI
Rattus norvegicus : Atf2 (activating transcription factor 2)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_12175,331,734 - 175,427,776-NCBI
Human Genome Assembly HuRef2167,817,672 - 167,913,976-NCBI
Human Genome Assembly GRCh372175,936,978 - 176,032,934-NCBI
Human Genome Assembly Build 362175,647,252 - 175,741,143-NCBI
Human Cytogenetic Map2q32 NCBI
Human Genome Assembly2175,764,514 - 175,858,404 NCBI
Model

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Sequence

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Additional Information

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Nomenclature History
  
More on ATF2
Entrez Gene
Ensembl Gene
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Vista + UCSC

RGD Object Information
RGD ID: 732287
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE



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