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1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
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Accession:CHEBI:77397 term browser browse the term
Definition:A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Synonyms:related_synonym: Formula=C20H21FN2O;   InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3;   InChIKey=WSEQXVZVJXJVFP-UHFFFAOYSA-N;   SMILES=CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1
 xref: CAS:59729-33-8;   KEGG:C07572;   KEGG:D07704;   LINCS:LSM-1585
 xref_mesh: MESH:D015283
 cyclic_relationship: is_conjugate_base_of CHEBI:77408

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1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Citalopram results in increased expression of ABCC2 protein CTD PMID:12524417 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression EXP Citalopram results in decreased expression of ABL1 mRNA CTD PMID:28467792 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Adcy5 adenylate cyclase 5 increases expression EXP Citalopram results in increased expression of ADCY5 mRNA CTD PMID:28467792 NCBI chr11:78,976,861...79,123,343
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [Citalopram co-treated with Caffeine deficiency] results in increased expression of ADORA1 mRNA; [Citalopram co-treated with Caffeine] results in decreased expression of ADORA1 mRNA CTD PMID:29107002 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases expression		 ISO Citalopram inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]
Citalopram results in decreased expression of AHR mRNA		 CTD PMID:24316275 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Citalopram inhibits the reaction [convulxin results in increased phosphorylation of AKT1 protein] CTD PMID:30592962 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression EXP Citalopram results in decreased expression of APC2 mRNA CTD PMID:28467792 NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Aurka aurora kinase A decreases expression EXP
ISO		 Citalopram results in decreased expression of AURKA mRNA CTD PMID:28467792 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Axin1 axin 1 increases expression EXP Citalopram results in increased expression of AXIN1 mRNA CTD PMID:28467792 NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP Citalopram results in increased expression of BAD mRNA CTD PMID:28467792 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression EXP
ISO		 Citalopram results in decreased expression of BARD1 mRNA CTD PMID:28467792 NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Citalopram results in increased expression of BCL2L1 mRNA CTD PMID:28467792 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP
ISO		 Citalopram results in decreased expression of BIRC5 mRNA CTD PMID:28467792 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression EXP Citalopram results in decreased expression of BMP7 mRNA CTD PMID:28467792 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression EXP Citalopram results in decreased expression of BRCA2 mRNA CTD PMID:28467792 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:59,819...100,567 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression		 ISO
EXP		 Citalopram results in increased cleavage of and results in increased activity of CASP3 protein
Citalopram results in decreased expression of CASP3 mRNA		 CTD PMID:10487422 PMID:28467792 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases expression ISO Citalopram results in decreased expression of CAT protein CTD PMID:15309392 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav2 caveolin 2 decreases expression EXP Citalopram results in decreased expression of CAV2 mRNA CTD PMID:28467792 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Ccna2 cyclin A2 decreases expression EXP
ISO		 Citalopram results in decreased expression of CCNA2 mRNA CTD PMID:28467792 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Citalopram results in decreased expression of CCND1 mRNA CTD PMID:28467792 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO
EXP		 Citalopram results in decreased expression of CCNE1 mRNA CTD PMID:28467792 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 decreases expression EXP Citalopram results in decreased expression of CCNE2 mRNA CTD PMID:28467792 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression EXP Citalopram results in decreased expression of CDK6 mRNA CTD PMID:28467792 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Citalopram results in increased expression of CDKN1A mRNA CTD PMID:28467792 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Citalopram results in increased expression of CDKN1B mRNA CTD PMID:28467792 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression EXP Citalopram results in decreased expression of CKS1B mRNA CTD PMID:28467792 NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:174,833,050...174,837,636 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Citalopram results in decreased expression of CNR1 protein CTD PMID:28866072 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression EXP Citalopram results in increased expression of CNR2 protein CTD PMID:28866072 NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression EXP Citalopram results in decreased expression of COL4A1 mRNA CTD PMID:28467792 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression EXP Citalopram results in decreased expression of COL4A2 mRNA CTD PMID:28467792 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Citalopram results in decreased phosphorylation of and results in decreased activity of CREB1 protein CTD PMID:20122921 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha increases expression EXP Citalopram results in increased expression of CSF2RA mRNA CTD PMID:28467792 NCBI chr14:113,219...118,808
Ensembl chr14:89,172...103,128 		JBrowse link
G Ctbp2 C-terminal binding protein 2 decreases expression EXP Citalopram results in decreased expression of CTBP2 mRNA CTD PMID:28467792 NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:187,782,682...187,920,222 		JBrowse link
G Cul2 cullin 2 decreases expression EXP Citalopram results in decreased expression of CUL2 mRNA CTD PMID:28467792 NCBI chr17:58,864,274...58,905,447
Ensembl chr17:54,169,086...54,209,968 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP Citalopram results in decreased expression of CXCL12 mRNA CTD PMID:28467792 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Citalopram results in decreased activity of CYP19A1 protein CTD PMID:26162595 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases methylation ISO CYP2C19 protein polymorphism results in decreased methylation of Citalopram; CYP2C19 protein results in decreased methylation of Citalopram analog CTD PMID:9110356 PMID:12975335 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases methylation ISO CYP2D6 protein results in decreased methylation of Citalopram analog CTD PMID:9110356 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases methylation ISO CYP3A4 protein results in decreased methylation of Citalopram analog CTD PMID:9110356 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP Citalopram results in decreased expression of DAPK1 mRNA CTD PMID:28467792 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dbh dopamine beta-hydroxylase multiple interactions ISO DBH protein promotes the reaction [Citalopram results in increased abundance of Serotonin] CTD PMID:15148402 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Dnmt1 DNA methyltransferase 1 affects expression EXP Citalopram affects the expression of DNMT1 mRNA CTD PMID:21682946 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha affects expression EXP Citalopram affects the expression of DNMT3A mRNA CTD PMID:21682946 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression EXP Citalopram results in decreased expression of DVL1 mRNA CTD PMID:28467792 NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression EXP Citalopram results in decreased expression of E2F1 mRNA CTD PMID:28467792 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression EXP Citalopram results in decreased expression of E2F8 mRNA CTD PMID:28467792 NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 increases expression EXP Citalopram results in increased expression of EGLN2 mRNA CTD PMID:28467792 NCBI chr 1:91,579,205...91,586,985
Ensembl chr 1:82,451,555...82,459,751 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression EXP Citalopram results in decreased expression of ERBB2 mRNA CTD PMID:28467792 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Citalopram results in increased expression of FABP1 mRNA CTD PMID:17567588 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Citalopram results in decreased expression of FAS mRNA CTD PMID:28467792 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fcer1g Fc epsilon receptor Ig multiple interactions ISO Citalopram inhibits the reaction [convulxin promotes the reaction [FCER1G protein binds to SYK protein]] CTD PMID:30592962 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression EXP Citalopram results in increased expression of FGF9 mRNA CTD PMID:28467792 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression EXP Citalopram results in decreased expression of FGFR1 mRNA CTD PMID:28467792 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fh fumarate hydratase decreases expression EXP Citalopram results in decreased expression of FH mRNA CTD PMID:28467792 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Citalopram results in increased expression of FOS mRNA CTD PMID:28467792 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression EXP Citalopram results in decreased expression of FZD1 mRNA CTD PMID:28467792 NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Citalopram results in increased expression of GDPD3 mRNA CTD PMID:17567588 NCBI chr 1:190,804,053...190,813,609
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Citalopram results in increased expression of GRB2 mRNA CTD PMID:28467792 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 affects response to substance ISO GRIA1 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 affects response to substance ISO GRIA3 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr  X:125,103,975...125,369,690
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 affects response to substance ISO GRIK2 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr20:53,717,564...54,415,283
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP Citalopram results in decreased expression of GRIN2B protein CTD PMID:23260230 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A affects response to substance ISO GRIN3A polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr 5:68,802,333...69,001,880
Ensembl chr 5:64,009,980...64,206,085 		JBrowse link
G Hdac1 histone deacetylase 1 decreases expression EXP Citalopram results in decreased expression of HDAC1 mRNA CTD PMID:28467792 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Citalopram results in increased expression of HMGCS1 mRNA CTD PMID:16324787 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression EXP Citalopram results in increased expression of HRAS mRNA CTD PMID:28467792 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression EXP Citalopram results in decreased expression of HTR1B protein CTD PMID:18157704 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding ISO Citalopram binds to HTR2C protein CTD PMID:18083778 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP Citalopram results in decreased expression of IGF1 mRNA CTD PMID:28467792 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP Citalopram results in decreased expression of IGF2 mRNA CTD PMID:28467792 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases expression EXP Citalopram results in increased expression of IKBKB mRNA CTD PMID:28467792 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il6 interleukin 6 increases expression EXP Citalopram results in increased expression of IL6 mRNA CTD PMID:28467792 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Citalopram results in increased expression of INHBE mRNA CTD PMID:17567588 NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Itga3 integrin subunit alpha 3 increases expression EXP Citalopram results in increased expression of ITGA3 mRNA CTD PMID:28467792 NCBI chr10:80,486,998...80,522,548
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Jak1 Janus kinase 1 increases expression EXP Citalopram results in increased expression of JAK1 mRNA CTD PMID:28467792 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Citalopram results in increased expression of JUN mRNA CTD PMID:28467792 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kitlg KIT ligand increases expression EXP Citalopram results in increased expression of KITLG mRNA CTD PMID:28467792 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 increases expression EXP Citalopram results in increased expression of LAMTOR1 mRNA CTD PMID:28467792 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:156,272,064...156,291,179 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression EXP Citalopram results in increased expression of LAMTOR3 mRNA CTD PMID:28467792 NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 increases expression EXP Citalopram results in increased expression of LAMTOR4 mRNA CTD PMID:28467792 NCBI chr12:22,372,269...22,376,090
Ensembl chr12:17,258,623...17,262,480 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 increases expression EXP Citalopram results in increased expression of LAMTOR5 mRNA CTD PMID:28467792 NCBI chr 2:197,588,242...197,593,598
Ensembl chr 2:194,900,038...194,905,395 		JBrowse link
G Lat linker for activation of T cells multiple interactions ISO Citalopram inhibits the reaction [convulxin results in increased phosphorylation of LAT protein] CTD PMID:30592962 NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:180,936,534...180,941,578 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression EXP Citalopram results in increased expression of MAP2K1 mRNA CTD PMID:28467792 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Citalopram results in increased expression of MDM2 mRNA CTD PMID:28467792 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mmp15 matrix metallopeptidase 15 decreases expression EXP Citalopram results in decreased expression of MMP15 mRNA CTD PMID:28467792 NCBI chr19:9,669,506...9,691,000
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression EXP Citalopram results in decreased expression of MMP2 mRNA CTD PMID:28467792 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP Citalopram results in decreased expression of MSH2 mRNA CTD PMID:28467792 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 decreases expression EXP Citalopram results in decreased expression of MSH3 mRNA CTD PMID:28467792 NCBI chr 2:25,179,400...25,320,857 JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression EXP
ISO		 Citalopram results in decreased expression of MYBL2 mRNA CTD PMID:28467792 NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP Citalopram results in increased expression of MYC mRNA CTD PMID:28467792 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression EXP Citalopram results in decreased expression of MYCN mRNA CTD PMID:28467792 NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression EXP Citalopram results in increased expression of NFKB2 mRNA CTD PMID:28467792 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP Citalopram results in increased expression of NFKBIA mRNA CTD PMID:28467792 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Npvf neuropeptide VF precursor affects expression ISO Citalopram affects the expression of NPVF mRNA CTD PMID:20381503 NCBI chr 4:81,043,128...81,047,045
Ensembl chr 4:79,712,520...79,716,236 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Citalopram inhibits the reaction [Dexamethasone results in increased expression of NR3C1 mRNA] CTD PMID:24316275 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 decreases expression EXP Citalopram results in decreased expression of NTRK1 mRNA CTD PMID:28467792 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO Citalopram results in increased phosphorylation of and results in increased activity of NTRK2 protein CTD PMID:21666748 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Citalopram results in increased expression of NUPR1 mRNA CTD PMID:17567588 NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Citalopram results in increased cleavage of PARP1 protein CTD PMID:10487422 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like decreases expression EXP Citalopram results in decreased expression of PDGFRL mRNA CTD PMID:28467792 NCBI chr16:58,051,421...58,111,327
Ensembl chr16:51,347,948...51,407,850 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression EXP Citalopram results in increased expression of PIK3CA mRNA CTD PMID:28467792 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pomc proopiomelanocortin increases expression ISO Citalopram results in increased expression of POMC protein CTD PMID:20414043 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prkca protein kinase C, alpha increases expression EXP Citalopram results in increased expression of PRKCA mRNA CTD PMID:28467792 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases expression		 ISO
EXP		 Citalopram inhibits the reaction [convulxin results in increased phosphorylation of PRKCD protein]
Citalopram results in increased expression of PRKCD mRNA		 CTD PMID:28467792 PMID:30592962 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression EXP Citalopram results in decreased expression of PRKDC mRNA CTD PMID:28467792 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prl prolactin affects secretion
increases expression
multiple interactions		 ISO Citalopram affects the secretion of PRL protein
Citalopram results in increased expression of PRL protein
SLC6A4 polymorphism inhibits the reaction [Citalopram affects the secretion of PRL protein]		 CTD PMID:17000009 PMID:19153152 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Rad51 RAD51 recombinase decreases expression EXP Citalopram results in decreased expression of RAD51 mRNA CTD PMID:28467792 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression EXP Citalopram results in increased expression of RAF1 mRNA CTD PMID:28467792 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Citalopram results in increased expression of RALA mRNA CTD PMID:28467792 NCBI chr17:51,787,682...51,840,738
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator increases expression EXP Citalopram results in increased expression of RALGDS mRNA CTD PMID:28467792 NCBI chr 3:32,237,644...32,278,045
Ensembl chr 3:11,839,416...11,880,059 		JBrowse link
G Rassf1 Ras association domain family member 1 decreases expression EXP Citalopram results in decreased expression of RASSF1 mRNA CTD PMID:28467792 NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rbx1 ring-box 1 increases expression EXP Citalopram results in increased expression of RBX1 mRNA CTD PMID:28467792 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rheb Ras homolog, mTORC1 binding decreases expression EXP Citalopram results in decreased expression of RHEB mRNA CTD PMID:28467792 NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Runx1 RUNX family transcription factor 1 decreases expression EXP Citalopram results in decreased expression of RUNX1 mRNA CTD PMID:28467792 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G S100a10 S100 calcium binding protein A10 affects expression EXP Citalopram affects the expression of S100A10 mRNA CTD PMID:21682946 NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Citalopram results in increased expression of SCD mRNA CTD PMID:16324787 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Serpina3n serpin family A member 3N increases expression ISO Citalopram results in increased expression of SERPINA3 mRNA CTD PMID:17567588 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression EXP Citalopram results in decreased expression of SKP2 mRNA CTD PMID:28467792 NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression EXP Citalopram results in increased expression of SLC2A1 mRNA CTD PMID:28467792 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Citalopram results in decreased expression of SLC2A3 mRNA CTD PMID:17567588 NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc32a1 solute carrier family 32 member 1 decreases expression EXP Citalopram results in decreased expression of SLC32A1 protein CTD PMID:20707986 NCBI chr 3:167,687,245...167,691,714
Ensembl chr 3:147,267,373...147,271,844 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 multiple interactions ISO [Citalopram co-treated with Caffeine] results in decreased expression of SLC6A15 mRNA CTD PMID:29107002 NCBI chr 7:40,439,607...40,493,788
Ensembl chr 7:38,553,196...38,607,239 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
affects response to substance		 ISO SLC6A3 mutant form promotes the reaction [Citalopram results in increased abundance of Dopamine]
[SLC6A3 protein polymorphism affects the susceptibility to Citalopram] which affects the uptake of Dopamine; Citalopram inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine]		 CTD PMID:14691264 PMID:31009648 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
affects response to substance		 ISO Citalopram binds to and results in decreased activity of SLC6A4 protein; Citalopram inhibits the reaction [convulxin promotes the reaction [SLC6A4 protein binds to SYK protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Dopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [tryptamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Tyramine results in increased activity of TAAR1 protein]]; SLC6A4 polymorphism inhibits the reaction [Citalopram affects the secretion of PRL protein]
SLC6A4 promoter polymorphism affects the susceptibility to Citalopram		 CTD PMID:14624186 PMID:16272152 PMID:17000009 PMID:17234900 PMID:30592962 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Smad4 SMAD family member 4 increases expression EXP Citalopram results in increased expression of SMAD4 mRNA CTD PMID:28467792 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smo smoothened, frizzled class receptor decreases expression EXP Citalopram results in decreased expression of SMO mRNA CTD PMID:28467792 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 increases expression EXP Citalopram results in increased expression of SOS2 mRNA CTD PMID:28467792 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:88,042,966...88,156,692 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO Citalopram results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Citalopram results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:16324787 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A increases expression EXP Citalopram results in increased expression of STAT5 mRNA CTD PMID:28467792 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases expression EXP Citalopram results in increased expression of STAT5B mRNA CTD PMID:28467792 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling increases expression EXP Citalopram results in increased expression of SUFU mRNA CTD PMID:28467792 NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Syk spleen associated tyrosine kinase multiple interactions ISO Citalopram inhibits the reaction [convulxin promotes the reaction [FCER1G protein binds to SYK protein]]; Citalopram inhibits the reaction [convulxin promotes the reaction [SLC6A4 protein binds to SYK protein]]; Citalopram inhibits the reaction [convulxin results in increased phosphorylation of SYK protein] CTD PMID:30592962 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Taar1 trace-amine-associated receptor 1 multiple interactions ISO Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Dopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [tryptamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Tyramine results in increased activity of TAAR1 protein]] CTD PMID:17234900 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:21,517,258...21,532,084 		JBrowse link
G Tagln transgelin decreases expression ISO Citalopram results in decreased expression of TAGLN mRNA CTD PMID:17567588 NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Citalopram results in increased expression of VEGFA mRNA CTD PMID:28467792 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wnt1 Wnt family member 1 increases expression EXP Citalopram results in increased expression of WNT1 mRNA CTD PMID:28467792 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt6 Wnt family member 6 decreases expression EXP Citalopram results in decreased expression of WNT6 mRNA CTD PMID:28467792 NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
citalopram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Citalopram results in increased expression of ABCC2 protein CTD PMID:12524417 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression EXP Citalopram results in decreased expression of ABL1 mRNA CTD PMID:28467792 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Adcy5 adenylate cyclase 5 increases expression EXP Citalopram results in increased expression of ADCY5 mRNA CTD PMID:28467792 NCBI chr11:78,976,861...79,123,343
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [Citalopram co-treated with Caffeine deficiency] results in increased expression of ADORA1 mRNA; [Citalopram co-treated with Caffeine] results in decreased expression of ADORA1 mRNA CTD PMID:29107002 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases expression		 ISO Citalopram inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]
Citalopram results in decreased expression of AHR mRNA		 CTD PMID:24316275 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Citalopram inhibits the reaction [convulxin results in increased phosphorylation of AKT1 protein] CTD PMID:30592962 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression EXP Citalopram results in decreased expression of APC2 mRNA CTD PMID:28467792 NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Aurka aurora kinase A decreases expression ISO
EXP		 Citalopram results in decreased expression of AURKA mRNA CTD PMID:28467792 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Axin1 axin 1 increases expression EXP Citalopram results in increased expression of AXIN1 mRNA CTD PMID:28467792 NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP Citalopram results in increased expression of BAD mRNA CTD PMID:28467792 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression ISO
EXP		 Citalopram results in decreased expression of BARD1 mRNA CTD PMID:28467792 NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Citalopram results in increased expression of BCL2L1 mRNA CTD PMID:28467792 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP
ISO		 Citalopram results in decreased expression of BIRC5 mRNA CTD PMID:28467792 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression EXP Citalopram results in decreased expression of BMP7 mRNA CTD PMID:28467792 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression EXP Citalopram results in decreased expression of BRCA2 mRNA CTD PMID:28467792 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:59,819...100,567 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression		 ISO
EXP		 Citalopram results in increased cleavage of and results in increased activity of CASP3 protein
Citalopram results in decreased expression of CASP3 mRNA		 CTD PMID:10487422 PMID:28467792 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases expression ISO Citalopram results in decreased expression of CAT protein CTD PMID:15309392 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav2 caveolin 2 decreases expression EXP Citalopram results in decreased expression of CAV2 mRNA CTD PMID:28467792 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Ccna2 cyclin A2 decreases expression EXP
ISO		 Citalopram results in decreased expression of CCNA2 mRNA CTD PMID:28467792 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Citalopram results in decreased expression of CCND1 mRNA CTD PMID:28467792 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO
EXP		 Citalopram results in decreased expression of CCNE1 mRNA CTD PMID:28467792 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 decreases expression EXP Citalopram results in decreased expression of CCNE2 mRNA CTD PMID:28467792 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression EXP Citalopram results in decreased expression of CDK6 mRNA CTD PMID:28467792 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Citalopram results in increased expression of CDKN1A mRNA CTD PMID:28467792 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Citalopram results in increased expression of CDKN1B mRNA CTD PMID:28467792 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression EXP Citalopram results in decreased expression of CKS1B mRNA CTD PMID:28467792 NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:174,833,050...174,837,636 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Citalopram results in decreased expression of CNR1 protein CTD PMID:28866072 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression EXP Citalopram results in increased expression of CNR2 protein CTD PMID:28866072 NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression EXP Citalopram results in decreased expression of COL4A1 mRNA CTD PMID:28467792 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression EXP Citalopram results in decreased expression of COL4A2 mRNA CTD PMID:28467792 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Citalopram results in decreased phosphorylation of and results in decreased activity of CREB1 protein CTD PMID:20122921 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha increases expression EXP Citalopram results in increased expression of CSF2RA mRNA CTD PMID:28467792 NCBI chr14:113,219...118,808
Ensembl chr14:89,172...103,128 		JBrowse link
G Ctbp2 C-terminal binding protein 2 decreases expression EXP Citalopram results in decreased expression of CTBP2 mRNA CTD PMID:28467792 NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:187,782,682...187,920,222 		JBrowse link
G Cul2 cullin 2 decreases expression EXP Citalopram results in decreased expression of CUL2 mRNA CTD PMID:28467792 NCBI chr17:58,864,274...58,905,447
Ensembl chr17:54,169,086...54,209,968 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP Citalopram results in decreased expression of CXCL12 mRNA CTD PMID:28467792 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Citalopram results in decreased activity of CYP19A1 protein CTD PMID:26162595 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases methylation ISO CYP2C19 protein polymorphism results in decreased methylation of Citalopram; CYP2C19 protein results in decreased methylation of Citalopram analog CTD PMID:9110356 PMID:12975335 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases methylation ISO CYP2D6 protein results in decreased methylation of Citalopram analog CTD PMID:9110356 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases methylation ISO CYP3A4 protein results in decreased methylation of Citalopram analog CTD PMID:9110356 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP Citalopram results in decreased expression of DAPK1 mRNA CTD PMID:28467792 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dbh dopamine beta-hydroxylase multiple interactions ISO DBH protein promotes the reaction [Citalopram results in increased abundance of Serotonin] CTD PMID:15148402 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Dnmt1 DNA methyltransferase 1 affects expression EXP Citalopram affects the expression of DNMT1 mRNA CTD PMID:21682946 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha affects expression EXP Citalopram affects the expression of DNMT3A mRNA CTD PMID:21682946 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression EXP Citalopram results in decreased expression of DVL1 mRNA CTD PMID:28467792 NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression EXP Citalopram results in decreased expression of E2F1 mRNA CTD PMID:28467792 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression EXP Citalopram results in decreased expression of E2F8 mRNA CTD PMID:28467792 NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 increases expression EXP Citalopram results in increased expression of EGLN2 mRNA CTD PMID:28467792 NCBI chr 1:91,579,205...91,586,985
Ensembl chr 1:82,451,555...82,459,751 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression EXP Citalopram results in decreased expression of ERBB2 mRNA CTD PMID:28467792 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Citalopram results in increased expression of FABP1 mRNA CTD PMID:17567588 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Citalopram results in decreased expression of FAS mRNA CTD PMID:28467792 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fcer1g Fc epsilon receptor Ig multiple interactions ISO Citalopram inhibits the reaction [convulxin promotes the reaction [FCER1G protein binds to SYK protein]] CTD PMID:30592962 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression EXP Citalopram results in increased expression of FGF9 mRNA CTD PMID:28467792 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression EXP Citalopram results in decreased expression of FGFR1 mRNA CTD PMID:28467792 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fh fumarate hydratase decreases expression EXP Citalopram results in decreased expression of FH mRNA CTD PMID:28467792 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Citalopram results in increased expression of FOS mRNA CTD PMID:28467792 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression EXP Citalopram results in decreased expression of FZD1 mRNA CTD PMID:28467792 NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Citalopram results in increased expression of GDPD3 mRNA CTD PMID:17567588 NCBI chr 1:190,804,053...190,813,609
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Citalopram results in increased expression of GRB2 mRNA CTD PMID:28467792 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 affects response to substance ISO GRIA1 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 affects response to substance ISO GRIA3 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr  X:125,103,975...125,369,690
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 affects response to substance ISO GRIK2 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr20:53,717,564...54,415,283
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP Citalopram results in decreased expression of GRIN2B protein CTD PMID:23260230 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A affects response to substance ISO GRIN3A polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 NCBI chr 5:68,802,333...69,001,880
Ensembl chr 5:64,009,980...64,206,085 		JBrowse link
G Hdac1 histone deacetylase 1 decreases expression EXP Citalopram results in decreased expression of HDAC1 mRNA CTD PMID:28467792 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Citalopram results in increased expression of HMGCS1 mRNA CTD PMID:16324787 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression EXP Citalopram results in increased expression of HRAS mRNA CTD PMID:28467792 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression EXP Citalopram results in decreased expression of HTR1B protein CTD PMID:18157704 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding ISO Citalopram binds to HTR2C protein CTD PMID:18083778 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP Citalopram results in decreased expression of IGF1 mRNA CTD PMID:28467792 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP Citalopram results in decreased expression of IGF2 mRNA CTD PMID:28467792 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases expression EXP Citalopram results in increased expression of IKBKB mRNA CTD PMID:28467792 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il6 interleukin 6 increases expression EXP Citalopram results in increased expression of IL6 mRNA CTD PMID:28467792 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Citalopram results in increased expression of INHBE mRNA CTD PMID:17567588 NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Itga3 integrin subunit alpha 3 increases expression EXP Citalopram results in increased expression of ITGA3 mRNA CTD PMID:28467792 NCBI chr10:80,486,998...80,522,548
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Jak1 Janus kinase 1 increases expression EXP Citalopram results in increased expression of JAK1 mRNA CTD PMID:28467792 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Citalopram results in increased expression of JUN mRNA CTD PMID:28467792 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kitlg KIT ligand increases expression EXP Citalopram results in increased expression of KITLG mRNA CTD PMID:28467792 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 increases expression EXP Citalopram results in increased expression of LAMTOR1 mRNA CTD PMID:28467792 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:156,272,064...156,291,179 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression EXP Citalopram results in increased expression of LAMTOR3 mRNA CTD PMID:28467792 NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 increases expression EXP Citalopram results in increased expression of LAMTOR4 mRNA CTD PMID:28467792 NCBI chr12:22,372,269...22,376,090
Ensembl chr12:17,258,623...17,262,480 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 increases expression EXP Citalopram results in increased expression of LAMTOR5 mRNA CTD PMID:28467792 NCBI chr 2:197,588,242...197,593,598
Ensembl chr 2:194,900,038...194,905,395 		JBrowse link
G Lat linker for activation of T cells multiple interactions ISO Citalopram inhibits the reaction [convulxin results in increased phosphorylation of LAT protein] CTD PMID:30592962 NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:180,936,534...180,941,578 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression EXP Citalopram results in increased expression of MAP2K1 mRNA CTD PMID:28467792 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Citalopram results in increased expression of MDM2 mRNA CTD PMID:28467792 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mmp15 matrix metallopeptidase 15 decreases expression EXP Citalopram results in decreased expression of MMP15 mRNA CTD PMID:28467792 NCBI chr19:9,669,506...9,691,000
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression EXP Citalopram results in decreased expression of MMP2 mRNA CTD PMID:28467792 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP Citalopram results in decreased expression of MSH2 mRNA CTD PMID:28467792 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 decreases expression EXP Citalopram results in decreased expression of MSH3 mRNA CTD PMID:28467792 NCBI chr 2:25,179,400...25,320,857 JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO
EXP		 Citalopram results in decreased expression of MYBL2 mRNA CTD PMID:28467792 NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP Citalopram results in increased expression of MYC mRNA CTD PMID:28467792 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression EXP Citalopram results in decreased expression of MYCN mRNA CTD PMID:28467792 NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression EXP Citalopram results in increased expression of NFKB2 mRNA CTD PMID:28467792 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP Citalopram results in increased expression of NFKBIA mRNA CTD PMID:28467792 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Npvf neuropeptide VF precursor affects expression ISO Citalopram affects the expression of NPVF mRNA CTD PMID:20381503 NCBI chr 4:81,043,128...81,047,045
Ensembl chr 4:79,712,520...79,716,236 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Citalopram inhibits the reaction [Dexamethasone results in increased expression of NR3C1 mRNA] CTD PMID:24316275 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 decreases expression EXP Citalopram results in decreased expression of NTRK1 mRNA CTD PMID:28467792 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO Citalopram results in increased phosphorylation of and results in increased activity of NTRK2 protein CTD PMID:21666748 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Citalopram results in increased expression of NUPR1 mRNA CTD PMID:17567588 NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Citalopram results in increased cleavage of PARP1 protein CTD PMID:10487422 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like decreases expression EXP Citalopram results in decreased expression of PDGFRL mRNA CTD PMID:28467792 NCBI chr16:58,051,421...58,111,327
Ensembl chr16:51,347,948...51,407,850 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression EXP Citalopram results in increased expression of PIK3CA mRNA CTD PMID:28467792 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pomc proopiomelanocortin increases expression ISO Citalopram results in increased expression of POMC protein CTD PMID:20414043 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prkca protein kinase C, alpha increases expression EXP Citalopram results in increased expression of PRKCA mRNA CTD PMID:28467792 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases expression		 ISO
EXP		 Citalopram inhibits the reaction [convulxin results in increased phosphorylation of PRKCD protein]
Citalopram results in increased expression of PRKCD mRNA		 CTD PMID:28467792 PMID:30592962 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression EXP Citalopram results in decreased expression of PRKDC mRNA CTD PMID:28467792 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prl prolactin affects secretion
multiple interactions
increases expression		 ISO Citalopram affects the secretion of PRL protein
SLC6A4 polymorphism inhibits the reaction [Citalopram affects the secretion of PRL protein]
Citalopram results in increased expression of PRL protein		 CTD PMID:17000009 PMID:19153152 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Rad51 RAD51 recombinase decreases expression EXP Citalopram results in decreased expression of RAD51 mRNA CTD PMID:28467792 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression EXP Citalopram results in increased expression of RAF1 mRNA CTD PMID:28467792 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Citalopram results in increased expression of RALA mRNA CTD PMID:28467792 NCBI chr17:51,787,682...51,840,738
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator increases expression EXP Citalopram results in increased expression of RALGDS mRNA CTD PMID:28467792 NCBI chr 3:32,237,644...32,278,045
Ensembl chr 3:11,839,416...11,880,059 		JBrowse link
G Rassf1 Ras association domain family member 1 decreases expression EXP Citalopram results in decreased expression of RASSF1 mRNA CTD PMID:28467792 NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rbx1 ring-box 1 increases expression EXP Citalopram results in increased expression of RBX1 mRNA CTD PMID:28467792 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rheb Ras homolog, mTORC1 binding decreases expression EXP Citalopram results in decreased expression of RHEB mRNA CTD PMID:28467792 NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Runx1 RUNX family transcription factor 1 decreases expression EXP Citalopram results in decreased expression of RUNX1 mRNA CTD PMID:28467792 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G S100a10 S100 calcium binding protein A10 affects expression EXP Citalopram affects the expression of S100A10 mRNA CTD PMID:21682946 NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Citalopram results in increased expression of SCD mRNA CTD PMID:16324787 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Serpina3n serpin family A member 3N increases expression ISO Citalopram results in increased expression of SERPINA3 mRNA CTD PMID:17567588 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression EXP Citalopram results in decreased expression of SKP2 mRNA CTD PMID:28467792 NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression EXP Citalopram results in increased expression of SLC2A1 mRNA CTD PMID:28467792 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Citalopram results in decreased expression of SLC2A3 mRNA CTD PMID:17567588 NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc32a1 solute carrier family 32 member 1 decreases expression EXP Citalopram results in decreased expression of SLC32A1 protein CTD PMID:20707986 NCBI chr 3:167,687,245...167,691,714
Ensembl chr 3:147,267,373...147,271,844 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 multiple interactions ISO [Citalopram co-treated with Caffeine] results in decreased expression of SLC6A15 mRNA CTD PMID:29107002 NCBI chr 7:40,439,607...40,493,788
Ensembl chr 7:38,553,196...38,607,239 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
affects response to substance		 ISO SLC6A3 mutant form promotes the reaction [Citalopram results in increased abundance of Dopamine]
[SLC6A3 protein polymorphism affects the susceptibility to Citalopram] which affects the uptake of Dopamine; Citalopram inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine]		 CTD PMID:14691264 PMID:31009648 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
affects response to substance		 ISO Citalopram binds to and results in decreased activity of SLC6A4 protein; Citalopram inhibits the reaction [convulxin promotes the reaction [SLC6A4 protein binds to SYK protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Dopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [tryptamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Tyramine results in increased activity of TAAR1 protein]]; SLC6A4 polymorphism inhibits the reaction [Citalopram affects the secretion of PRL protein]
SLC6A4 promoter polymorphism affects the susceptibility to Citalopram		 CTD PMID:14624186 PMID:16272152 PMID:17000009 PMID:17234900 PMID:30592962 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Smad4 SMAD family member 4 increases expression EXP Citalopram results in increased expression of SMAD4 mRNA CTD PMID:28467792 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smo smoothened, frizzled class receptor decreases expression EXP Citalopram results in decreased expression of SMO mRNA CTD PMID:28467792 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 increases expression EXP Citalopram results in increased expression of SOS2 mRNA CTD PMID:28467792 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:88,042,966...88,156,692 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO Citalopram results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Citalopram results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:16324787 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A increases expression EXP Citalopram results in increased expression of STAT5 mRNA CTD PMID:28467792 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases expression EXP Citalopram results in increased expression of STAT5B mRNA CTD PMID:28467792 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling increases expression EXP Citalopram results in increased expression of SUFU mRNA CTD PMID:28467792 NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Syk spleen associated tyrosine kinase multiple interactions ISO Citalopram inhibits the reaction [convulxin promotes the reaction [FCER1G protein binds to SYK protein]]; Citalopram inhibits the reaction [convulxin promotes the reaction [SLC6A4 protein binds to SYK protein]]; Citalopram inhibits the reaction [convulxin results in increased phosphorylation of SYK protein] CTD PMID:30592962 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Taar1 trace-amine-associated receptor 1 multiple interactions ISO Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Dopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [tryptamine results in increased activity of TAAR1 protein]]; Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Tyramine results in increased activity of TAAR1 protein]] CTD PMID:17234900 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:21,517,258...21,532,084 		JBrowse link
G Tagln transgelin decreases expression ISO Citalopram results in decreased expression of TAGLN mRNA CTD PMID:17567588 NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Citalopram results in increased expression of VEGFA mRNA CTD PMID:28467792 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wnt1 Wnt family member 1 increases expression EXP Citalopram results in increased expression of WNT1 mRNA CTD PMID:28467792 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt6 Wnt family member 6 decreases expression EXP Citalopram results in decreased expression of WNT6 mRNA CTD PMID:28467792 NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
escitalopram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression EXP Escitalopram results in decreased expression of ABL1 mRNA CTD PMID:28467792 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Adcy5 adenylate cyclase 5 increases expression EXP Escitalopram results in increased expression of ADCY5 mRNA CTD PMID:28467792 NCBI chr11:78,976,861...79,123,343
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression EXP Escitalopram results in decreased expression of APC2 mRNA CTD PMID:28467792 NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Aurka aurora kinase A decreases expression ISO
EXP		 Escitalopram results in decreased expression of AURKA mRNA CTD PMID:28467792 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP Escitalopram results in increased expression of BAD mRNA CTD PMID:28467792 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression EXP
ISO		 Escitalopram results in decreased expression of BARD1 mRNA CTD PMID:28467792 NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Escitalopram results in increased expression of BCL2L1 mRNA CTD PMID:28467792 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO
EXP		 Escitalopram results in decreased expression of BIRC5 mRNA CTD PMID:28467792 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression EXP Escitalopram results in decreased expression of BMP7 mRNA CTD PMID:28467792 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Casp3 caspase 3 decreases expression EXP Escitalopram results in decreased expression of CASP3 mRNA CTD PMID:28467792 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cav2 caveolin 2 decreases expression EXP Escitalopram results in decreased expression of CAV2 mRNA CTD PMID:28467792 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Ccna2 cyclin A2 decreases expression EXP
ISO		 Escitalopram results in decreased expression of CCNA2 mRNA CTD PMID:28467792 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Escitalopram results in decreased expression of CCND1 mRNA CTD PMID:28467792 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO
EXP		 Escitalopram results in decreased expression of CCNE1 mRNA CTD PMID:28467792 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 decreases expression EXP Escitalopram results in decreased expression of CCNE2 mRNA CTD PMID:28467792 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Escitalopram results in increased expression of CDKN1B mRNA CTD PMID:28467792 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression EXP Escitalopram results in decreased expression of CKS1B mRNA CTD PMID:28467792 NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:174,833,050...174,837,636 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression EXP Escitalopram results in decreased expression of COL4A1 mRNA CTD PMID:28467792 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression EXP Escitalopram results in decreased expression of COL4A2 mRNA CTD PMID:28467792 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha increases expression EXP Escitalopram results in increased expression of CSF2RA mRNA CTD PMID:28467792 NCBI chr14:113,219...118,808
Ensembl chr14:89,172...103,128 		JBrowse link
G Ctbp2 C-terminal binding protein 2 decreases expression EXP Escitalopram results in decreased expression of CTBP2 mRNA CTD PMID:28467792 NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:187,782,682...187,920,222 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP Escitalopram results in decreased expression of CXCL12 mRNA CTD PMID:28467792 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP Escitalopram results in decreased expression of DAPK1 mRNA CTD PMID:28467792 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression EXP Escitalopram decreases expression of Dnmt1 mRNA in FSL strain prefrontal cortex RGD PMID:21682946 RGD:9588311 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression EXP Escitalopram results in decreased expression of DVL1 mRNA CTD PMID:28467792 NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression EXP Escitalopram results in decreased expression of E2F1 mRNA CTD PMID:28467792 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression EXP Escitalopram results in decreased expression of E2F8 mRNA CTD PMID:28467792 NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression EXP Escitalopram results in decreased expression of ERBB2 mRNA CTD PMID:28467792 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Fadd Fas associated via death domain increases expression EXP Escitalopram results in increased expression of FADD mRNA CTD PMID:28467792 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression EXP Escitalopram results in increased expression of FGF9 mRNA CTD PMID:28467792 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression EXP Escitalopram results in decreased expression of FGFR1 mRNA CTD PMID:28467792 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Escitalopram results in increased expression of FOS mRNA CTD PMID:28467792 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression EXP Escitalopram results in decreased expression of FZD1 mRNA CTD PMID:28467792 NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Escitalopram results in increased expression of GRB2 mRNA CTD PMID:28467792 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression EXP Escitalopram results in increased expression of HRAS mRNA CTD PMID:28467792 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP Escitalopram results in decreased expression of IGF2 mRNA CTD PMID:28467792 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases expression EXP Escitalopram results in increased expression of IKBKB mRNA CTD PMID:28467792 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Jak1 Janus kinase 1 increases expression EXP Escitalopram results in increased expression of JAK1 mRNA CTD PMID:28467792 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Escitalopram results in increased expression of JUN mRNA CTD PMID:28467792 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kitlg KIT ligand increases expression EXP Escitalopram results in increased expression of KITLG mRNA CTD PMID:28467792 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 increases expression EXP Escitalopram results in increased expression of LAMTOR1 mRNA CTD PMID:28467792 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:156,272,064...156,291,179 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression EXP Escitalopram results in increased expression of LAMTOR3 mRNA CTD PMID:28467792 NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 increases expression EXP Escitalopram results in increased expression of LAMTOR4 mRNA CTD PMID:28467792 NCBI chr12:22,372,269...22,376,090
Ensembl chr12:17,258,623...17,262,480 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 increases expression EXP Escitalopram results in increased expression of LAMTOR5 mRNA CTD PMID:28467792 NCBI chr 2:197,588,242...197,593,598
Ensembl chr 2:194,900,038...194,905,395 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression EXP Escitalopram results in increased expression of MAP2K1 mRNA CTD PMID:28467792 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Escitalopram results in increased expression of MDM2 mRNA CTD PMID:28467792 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression EXP Escitalopram results in decreased expression of MMP2 mRNA CTD PMID:28467792 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP Escitalopram results in decreased expression of MSH2 mRNA CTD PMID:28467792 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 decreases expression EXP Escitalopram results in decreased expression of MSH3 mRNA CTD PMID:28467792 NCBI chr 2:25,179,400...25,320,857 JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression EXP
ISO		 Escitalopram results in decreased expression of MYBL2 mRNA CTD PMID:28467792 NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP Escitalopram results in increased expression of MYC mRNA CTD PMID:28467792 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression EXP Escitalopram results in decreased expression of MYCN mRNA CTD PMID:28467792 NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP Escitalopram results in increased expression of NFKBIA mRNA CTD PMID:28467792 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like decreases expression EXP Escitalopram results in decreased expression of PDGFRL mRNA CTD PMID:28467792 NCBI chr16:58,051,421...58,111,327
Ensembl chr16:51,347,948...51,407,850 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression EXP Escitalopram results in increased expression of PIK3CA mRNA CTD PMID:28467792 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Prkca protein kinase C, alpha increases expression EXP Escitalopram results in increased expression of PRKCA mRNA CTD PMID:28467792 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcd protein kinase C, delta increases expression EXP Escitalopram results in increased expression of PRKCD mRNA CTD PMID:28467792 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Rad51 RAD51 recombinase decreases expression EXP Escitalopram results in decreased expression of RAD51 mRNA CTD PMID:28467792 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression EXP Escitalopram results in increased expression of RAF1 mRNA CTD PMID:28467792 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Escitalopram results in increased expression of RALA mRNA CTD PMID:28467792 NCBI chr17:51,787,682...51,840,738
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator increases expression EXP Escitalopram results in increased expression of RALGDS mRNA CTD PMID:28467792 NCBI chr 3:32,237,644...32,278,045
Ensembl chr 3:11,839,416...11,880,059 		JBrowse link
G Rbx1 ring-box 1 increases expression EXP Escitalopram results in increased expression of RBX1 mRNA CTD PMID:28467792 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Runx1 RUNX family transcription factor 1 decreases expression EXP Escitalopram results in decreased expression of RUNX1 mRNA CTD PMID:28467792 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression EXP Escitalopram results in decreased expression of SKP2 mRNA CTD PMID:28467792 NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression EXP Escitalopram results in increased expression of SLC2A1 mRNA CTD PMID:28467792 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Smad4 SMAD family member 4 increases expression EXP Escitalopram results in increased expression of SMAD4 mRNA CTD PMID:28467792 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smo smoothened, frizzled class receptor decreases expression EXP Escitalopram results in decreased expression of SMO mRNA CTD PMID:28467792 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 increases expression EXP Escitalopram results in increased expression of SOS2 mRNA CTD PMID:28467792 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:88,042,966...88,156,692 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Escitalopram results in increased expression of STAT3 mRNA CTD PMID:28467792 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling increases expression EXP Escitalopram results in increased expression of SUFU mRNA CTD PMID:28467792 NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression EXP Escitalopram results in decreased expression of TGFB2 mRNA CTD PMID:28467792 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Traf4 Tnf receptor associated factor 4 decreases expression EXP Escitalopram results in decreased expression of TRAF4 mRNA CTD PMID:28467792 NCBI chr10:63,552,251...63,558,356
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Escitalopram results in increased expression of VEGFA mRNA CTD PMID:28467792 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wnt6 Wnt family member 6 decreases expression EXP Escitalopram results in decreased expression of WNT6 mRNA CTD PMID:28467792 NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      group 19837
        pseudohalo group 4624
          cyano group 4624
            nitrile 4624
              1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile 142
                (R)-citalopram + 138
                escitalopram + 142
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    main group molecular entity 19824
                      s-block molecular entity 19658
                        hydrogen molecular entity 19640
                          hydrides 19145
                            inorganic hydride 18162
                              pnictogen hydride 18152
                                nitrogen hydride 18059
                                  azane 17869
                                    ammonia 17868
                                      organic amino compound 17868
                                        tertiary amino compound 10162
                                          1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile 142
                                            (R)-citalopram + 138
                                            escitalopram + 142
paths to the root