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Gene: Msh3 (mutS homolog 3) Rattus norvegicus
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Symbol: Msh3
Name: mutS homolog 3
Description: Predicted to contribute to dinucleotide repeat insertion binding activity; single guanine insertion binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA metabolic process; negative regulation of DNA recombination; and positive regulation of helicase activity. Predicted to localize to the MutSbeta complex. Human ortholog(s) of this gene implicated in colorectal carcinoma; endometrial cancer; endometrial carcinoma; and familial adenomatous polyposis 4. Orthologous to human MSH3 (mutS homolog 3); PARTICIPATES IN mismatch repair pathway; colorectal cancer pathway; INTERACTS WITH (+)-schisandrin B; bisphenol A; cyclophosphamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA mismatch repair protein Msh3; mutS homolog 3 (E. coli)
Orthologs:
Homo sapiens (human) : MSH3 (mutS homolog 3)  HGNC  Alliance
Mus musculus (house mouse) : Msh3 (mutS homolog 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msh3 (mutS homolog 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MSH3 (mutS homolog 3)
Canis lupus familiaris (dog) : MSH3 (mutS homolog 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msh3 (mutS homolog 3)
Sus scrofa (pig) : MSH3 (mutS homolog 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0221,790,048 - 21,931,791 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl221,790,044 - 21,931,720 (-)Ensembl
Rnor_5.0240,996,035 - 41,137,686 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4222,462,934 - 22,606,874 (-)NCBIRGSC3.4rn4RGSC3.4
Celera219,534,848 - 19,675,746 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Msh3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563954
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.