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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nitrile
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Accession:CHEBI:18379 term browser browse the term
Definition:A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it.
Synonyms:exact_synonym: nitriles
 related_synonym: Formula=CNR;   Nitril;   R-CN;   SMILES=[*]C#N;   a nitrile;   nitrilos
 alt_id: CHEBI:13212;   CHEBI:13426;   CHEBI:13660;   CHEBI:25547;   CHEBI:7584
 xref: KEGG:C00726


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      CHEBI ontology 19874
        chemical entity 19872
          group 19825
            pseudohalo group 4580
              cyano group 4580
                nitrile 4580
                  ((2-bromo-4-methylphenyl)\{6-[(4-\{[3-(dimethylamino)-2-hydroxypropyl]oxy\}phenyl)amino]pyrimidin-4-yl\}amino)acetonitrile + 0
                  (+-)-2-(4'-isobutylphenyl)propionitrile 0
                  (1R)-2-[(cyanomethyl)amino]-1-(\{[2-(difluoromethoxy)benzyl]sulfonyl\}methyl)-2-oxoethyl morpholine-4-carboxylate 0
                  (1R,5S)-7-[4-(3-cyanophenyl)phenyl]-N-(3-fluorophenyl)-3,6-diazabicyclo[3.1.1]heptane-6-carboxamide 0
                  (1R,5S)-7-[4-(4-cyanophenyl)phenyl]-N-cyclohexyl-3,6-diazabicyclo[3.1.1]heptane-6-carboxamide 0
                  (1R,5S)-N-(4-chlorophenyl)-7-[4-(4-cyanophenyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane-6-carboxamide 0
                  (1S,5R)-7-[4-(3-cyanophenyl)phenyl]-N-(2-methoxyphenyl)-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide 0
                  (1S,5R)-7-[4-(3-cyanophenyl)phenyl]-N-[4-(trifluoromethyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide 0
                  (1S,5R)-N-(1,3-benzodioxol-5-yl)-7-[4-(4-cyanophenyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide 0
                  (2,2,3-trimethylcyclopent-3-en-1-yl)acetonitrile 0
                  (2-methylphenyl)acetonitrile 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-pyrrolidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-pyrrolidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyrrolidin-1-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-pyrrolidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                  (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-phenyl-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-N-(3-fluorophenyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-N-(4-fluorophenyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8R,9R,10R)-9-[4-(4-cyanophenyl)phenyl]-N-(4-fluorophenyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8R,9R,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8R,9S,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8R,9S,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8S,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8S,9R,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8S,9S,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (8S,9S,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                  (E)-12-methyltridec-3-enenitrile 0
                  (E)-13-methyltetradec-3-enenitrile 0
                  (E)-3-tosylacrylonitrile 0
                  (E)-tetradec-3-enenitrile 0
                  (R)-4-hydroxymandelonitrile beta-D-glucoside 0
                  (S)-4-hydroxymandelonitrile beta-D-glucoside 0
                  (Z)-12-methyltetradec-3-enenitrile 0
                  (Z)-12-methyltridec-3-enenitrile 0
                  (Z)-13-methyltetradec-3-enenitrile 0
                  (Z)-14-methylpentadec-3-enenitrile 0
                  (Z)-docos-9-enenitrile 0
                  (Z)-hexadec-3-enenitrile 0
                  (Z)-hexadec-9-enenitrile 0
                  (Z)-octadec-11-enenitrile 0
                  (Z)-pentadec-3-enenitrile 0
                  (Z)-tetradec-3-enenitrile 0
                  (Z)-tetradec-7-enenitrile 0
                  1,3,5-triazinylamino nitrile + 10
                  1,3-Di-(octadec-9Z-enoyl)-1-cyano-2-methylene-propane-1,3-diol 0
                  1,5-diamino-1H-imidazole-4-carbonitrile 0
                  1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-cyanopyrazin-2-yl)urea 0
                  1-Cyano-2-hydroxymethylprop-1-ene-3-ol 0
                  1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-[(2-methylprop-2-en-1-yl)amino]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile + 0
                  1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile + 50
                  1-\{[1-(2-amino-3-phenylpropionyl)pyrrolidine-2-carbonyl]amino\}-2-(3-cyanophenyl)ethaneboronic acid 0
                  1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                  13-methyltetradecanenitrile 0
                  2,2'-(5-hydroxy-1,3-phenylene)bis(2-methylpropanenitrile) 0
                  2,3-bis(4-hydroxyphenyl)propionitrile 46
                  2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile 0
                  2,6-diamino-4-(1-phenylethyl)-4H-thiopyran-3,5-dicarbonitrile 0
                  2,6-dichlorobenzonitrile 2
                  2-(1-piperidinyl)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile 0
                  2-(2,6-dihydroxy-3,4-dimethoxycyclohexylidene)acetonitrile 0
                  2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile + 126
                  2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl]amino\}-2-(propan-2-yl)pentanenitrile + 1
                  2-(3-Methoxyphenyl)acetonitrile 0
                  2-(4-Chloro-2-fluorophenyl)acetonitrile 0
                  2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile + 0
                  2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile 0
                  2-(4-fluorophenyl)-2-[4-[(4-fluorophenyl)-oxomethyl]phenyl]acetonitrile 0
                  2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile 0
                  2-(5-amino-4-cyano-1H-imidazol-1-yl)-5-(4-methylpiperazin-1-yl)benzoic acid 0
                  2-(5-amino-4-cyano-1H-imidazol-1-yl)benzoic acid 0
                  2-(methylamino)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile 0
                  2-(thiiran-2-yl)acetonitrile 0
                  2-Cyanophenol 0
                  2-Hydroxy-4,6-dimethylnicotinonitrile 0
                  2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile 0
                  2-Methoxy-6-(2,2,2-trifluoroethoxy)benzonitrile 0
                  2-Methyl-6-(trifluoromethyl)nicotinonitrile 0
                  2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile 0
                  2-[(4-chlorophenyl)methoxy]-6-methoxybenzonitrile 0
                  2-[3-(4-cyanoanilino)-1-(dimethylamino)prop-2-enylidene]propanedinitrile 0
                  2-[3-(diethylamino)propylamino]-4-(methoxymethyl)-6-methyl-3-pyridinecarbonitrile 0
                  2-\{5-amino-4-[cyano(imino)methyl]-1H-imidazol-1-yl\}-3-phenylpropanoic acid 0
                  2-\{[3-(Dimethylamino)propyl]amino\}-6-fluorobenzonitrile 0
                  2-amino-2-phenylacetonitrile 0
                  2-amino-3-cyano-7-(dimethylamino)-4-(2-methoxyphenyl)-4H-chromene 0
                  2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene 1
                  2-amino-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzonitrile 0
                  2-amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrile 0
                  2-cyano-3-cyclopropyl-1-(2-mesyl-4-trifluoromethylphenyl)propan-1,3-dione 0
                  2-cyano-N-[1-(2,4-dichlorophenyl)ethyl]-3,3-dimethylbutanamide + 0
                  2-fluoro-6-(4-methoxyphenoxy)benzonitrile 0
                  2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate + 0
                  2-methyl-Pentanedinitrile 0
                  2-oxo-4,6-dithiophen-2-yl-1H-pyridine-3-carbonitrile 0
                  2-thienylacetonitrile 0
                  3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin 1
                  3-(5-\{[4-(aminomethyl)piperidin-1-yl]methyl\}-1H-indol-2-yl)-1H-indazole-6-carbonitrile 0
                  3-(\{[(2S)-5-oxopyrrolidin-2-yl]methyl\}sulfonyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-L-alanin[N-(1-cyanocyclopropyl)]amide 0
                  3-Ethylbenzonitrile 0
                  3-O-14,15-Eicosylenoyl-1-cyano-2-methyl-1,2-propene 0
                  3-O-ethylentacapone 0
                  3-O-methylentacapone 0
                  3-[(4R,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4S,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4S,5S)-5-[(dimethylamino)methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4S,5S)-5-[(dimethylamino)methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[(4S,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  3-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-(piperidine-1-carbonyl)-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  3-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[oxo(1-piperidinyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  3-[4-[(1R,5S)-3-(2-methylphenyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(1R,5S)-3-(phenylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(1R,5S)-3-[1,3-benzodioxol-5-yl(oxo)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(1R,5S)-3-[oxo(3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(1R,5S)-6-[(2-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(1S,5R)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(1S,5R)-3-(4-oxazolylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(1S,5R)-3-[(2-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  3-[4-[(2R,3R)-6-acetyl-2-(hydroxymethyl)-1-(3,3,3-trifluoropropyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                  3-[4-[(2S,3R)-6-acetyl-2-(hydroxymethyl)-1-(3,3,3-trifluoropropyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                  3-[4-[(2S,3S)-6-acetyl-2-(hydroxymethyl)-1-(3,3,3-trifluoropropyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-(1-oxo-2-phenylethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-(1-oxo-2-pyridin-4-ylethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-[1-oxo-2-(3-pyridinyl)ethyl]-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-methylsulfonyl-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9R,10R)-6-(benzenesulfonyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9R,10R)-6-ethylsulfonyl-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9R,10S)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8R,9S,10S)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8S,9R,10R)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8S,9S,10R)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[4-[(8S,9S,10S)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  3-[di(propan-2-yl)phosphorylmethyl]benzonitrile 0
                  3-\{[(9-cyano-10-methyl-9,10-dihydroacridin-9-yl)carbonyl]amino\}propanoic acid 0
                  3-amino-7-(4-methylpiperazin-1-yl)-9-oxo-9H-imidazo[1,2-a]indole-2-carbonitrile 0
                  3-amino-9-oxo-9H-imidazo[1,2-a]indole-2-carbonitrile 0
                  3-cyano-2-butanone 0
                  3-cyano-2-pyridone 0
                  3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone 0
                  3-hydroxy-3-phenylpropionitrile 0
                  3-hydroxypent-4-ene nitrile 0
                  3-phenylpropionitrile + 0
                  3-pyridinecarbonitrile 0
                  4,4'-dimethoxy[1,1'-biphenyl]-2-carbonitrile 0
                  4,6-dimethyl-2-[3-(4-morpholinyl)propylamino]-3-pyridinecarbonitrile 0
                  4-(1H-imidazol-1-ylmethyl)benzonitrile 0
                  4-(2-Hydroxyethyl)benzonitrile 0
                  4-(2-furyl)-2-oxo-6-(2-thienyl)-1,2-dihydro-3-pyridinecarbonitrile 0
                  4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile + 33
                  4-(Trifluoromethoxy)phenylacetonitrile 0
                  4-(Trifluoromethyl)nicotinonitrile 0
                  4-(\{(2R,5S)-2,5-dimethyl-4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperazin-1-yl\}carbonyl)benzonitrile 0
                  4-(\{4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl\}amino)benzonitrile 0
                  4-(\{5-bromo-2-[(4-cyanophenyl)amino]-6-(hydroxymethyl)pyrimidin-4-yl\}oxy)-3,5-dimethylbenzonitrile 0
                  4-(\{6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-sulfanyl-1H-1,2,4-triazol-1-yl)propyl]pyridin-3-yl\}oxy)benzonitrile + 0
                  4-(\{6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-sulfanylidene-2,5-dihydro-1H-1,2,4-triazol-1-yl)propyl]pyridin-3-yl\}oxy)benzonitrile + 0
                  4-(\{6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl\}oxy)-3,5-dimethylbenzonitrile 0
                  4-(methoxymethyl)-6-methyl-2-(2-methylanilino)-3-pyridinecarbonitrile 0
                  4-(morpholinocarbothioyl)benzonitrile 0
                  4-Amino-3-chlorobenzonitrile 0
                  4-Chlorobenzonitrile 0
                  4-Fluorobenzonitrile 0
                  4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile 0
                  4-[(4R,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4R,5R)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4R,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4R,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4R,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5R)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5R)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-(methylaminomethyl)-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[(4S,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                  4-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[(4-methyl-1-piperazinyl)-oxomethyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  4-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[4-morpholinyl(oxo)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  4-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[oxo(1-piperidinyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  4-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-(piperidine-1-carbonyl)-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  4-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[(4-methyl-1-piperazinyl)-oxomethyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  4-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[4-morpholinyl(oxo)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                  4-[4-[(1R,5S)-3-(2-methylphenyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1R,5S)-6-[(3-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-(1-oxo-2-phenylethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-(4-fluorophenyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-(4-oxazolylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-(phenylmethyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-[(2-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-[(3,5-dimethoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-[cyclohexyl(oxo)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-3-[oxo(pyridin-4-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(1S,5R)-6-(1,3-benzodioxol-5-ylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(2R,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                  4-[4-[(2S,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                  4-[4-[(2S,3S)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7R,8R)-4-[cyclohexyl(oxo)methyl]-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7R,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7R,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7R,8S)-4-[cyclohexyl(oxo)methyl]-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7R,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7R,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7S,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7S,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7S,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6R,7S,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7R,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7R,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7R,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7R,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7S,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7S,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7S,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(6S,7S,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                  4-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-(1-oxo-2-phenylethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                  4-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]benzonitrile 0
                  4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrile 0
                  4-\{2-[(2-hydroxybenzyl)amino]ethyl\}-2,5-dimethoxybenzonitrile 0
                  4-chlorophenylacetonitrile 0
                  4-cyanobenzoyl chloride 0
                  4-hydroxychlorothalonil 0
                  4-phenyl-3-furoxancarbonitrile 3
                  5,7-dibromo-indole-3-carbonitrile 0
                  5-(methylsulfanyl)-2-(thiophen-2-yl)-3-(trifluoromethyl)pyridine-4-carbonitrile 0
                  5-(methylsulfanyl)pentanenitrile 0
                  5-Chloro-2-hydroxy-4,6-dimethylnicotinonitrile 0
                  5-\{N-[4-(4-cyanostyryl)phenyl]-N-methylamino\}pentanoic acid 0
                  5-allyl-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 0
                  5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile + 1160
                  5-amino-1-[3-fluoro-4-(morpholin-4-yl)phenyl]imidazole-4-carbonitrile 0
                  5-amino-1-anilinoimidazole-4-carbonitrile 0
                  5-amino-1-benzoylimidazole-4-carbonitrile 0
                  5-amino-1-formylimidazole-4-carbonitrile 0
                  5-amino-4-cyano-1H-imidazole-1-carboxamide 0
                  5-cyano-N-[5-(hydroxymethyl)-2-(4-methylpiperidin-1-yl)phenyl]furan-2-carboxamide 0
                  5-ethyl-4,6-dimethyl-2-sulfanylidene-1H-pyridine-3-carbonitrile 0
                  5-hydroxy-2-(4-hydroxyphenyl)-1-benzofuran-7-carbonitrile 0
                  5-methylsulfinylpentyl nitrile 0
                  6-(2-furyl)-2-hydroxy-4-(2-thienyl)nicotinonitrile 0
                  6-(2-furyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile 0
                  6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)ethyl]-9H-purine-2-carbonitrile 0
                  6-amino-1-(4-chlorophenyl)-2-oxo-4-(1,2,4-triazol-1-ylmethyl)-5-pyrimidinecarbonitrile 0
                  6-amino-3-(methoxymethyl)-5-spiro[2H-pyrano[2,3-c]pyrazole-4,4'-thiane]carbonitrile 0
                  6-hydroxy-1-(3-hydroxypropyl)-4-methyl-2-oxo-5-(1-piperidinylmethyl)-3-pyridinecarbonitrile 0
                  6-methoxynaphthalene-1-carbonitrile 0
                  6-methyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile 0
                  6-tert-butyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile 0
                  7-(Methylthio)heptanenitrile 0
                  7-cyano-7-deazaguanine 0
                  8-(Methylthio)octanenitrile 0
                  9-(Methylthio)nonanenitrile 0
                  9-cyclopentyl-6-\{2-[3-(4-methylpiperazin-1-yl)propoxy]phenylamino\}-9H-purine-2-carbonitrile 0
                  AM6545 14
                  AZ3451 0
                  AZD1080 0
                  BAY-826 0
                  BAY11-7085 0
                  BMS-214662 0
                  BPDZ 711 0
                  Bromochloroacetonitrile 5
                  CCCP 46
                  CNDAC + 0
                  CT3 0
                  Chloroacetonitrile 14
                  Chlorphoxim 0
                  Citalopram alcohol 0
                  Citalopram aldehyde 0
                  Citalopram propionic acid 0
                  Cyanofenphos 3
                  Cyanthoate 0
                  Cyometrinil 0
                  Cys(IAN)-Gly 0
                  D617 0
                  Dodecanenitrile 0
                  Fe(CN)2 0
                  GS-441524 + 27
                  GS-441524 monophosphate 0
                  GS-443902 0
                  Girgensonine 0
                  Hexadecanenitrile 0
                  Hexanenitrile 0
                  Isoamyl cyanide 0
                  L-778,123 (free base) + 0
                  L-Cys(IAN) 0
                  LFM-A13 0
                  LLY-507 8
                  Methylacrylonitrile 2
                  Mirabilene E isonitrile 0
                  N-(2-[(2-aminoethyl)(methyl)amino]-5-\{[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino\}phenyl)acetamide 0
                  N-(2-cyano-3-methylbutan-2-yl)-2-(2,4-dichlorophenoxy)propanamide + 0
                  N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide 0
                  N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide 0
                  N-[3-cyano-6-(3-piperidin-1-ylpropanoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]naphthalene-1-carboxamide 0
                  N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide + 203
                  N-[[(2R,3S,4S)-1-acetyl-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-N-methylacetamide 0
                  N-[[(2S,3R,4R)-1-acetyl-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-N-methylacetamide 0
                  N-[[(2S,3R,4S)-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]cyclobutanecarboxamide 0
                  N-[[(2S,3S,4R)-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-(dimethylamino)acetamide 0
                  N-[[(4R,5R)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[[(4R,5R)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[[(4R,5S)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[[(4R,5S)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[[(4S,5R)-8-(3-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-N-methylcyclopropanecarboxamide 0
                  N-[[(4S,5R)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[[(4S,5R)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[[(4S,5S)-8-(3-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-N-methylcyclopropanecarboxamide 0
                  N-[[(4S,5S)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[[(4S,5S)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                  N-[cyano(2-thienyl)methyl]-4-ethyl-2-(ethylamino)-1,3-thiazole-5-carboxamide + 0
                  N-\{(1S)-1-[(1R)-2-benzyloxy-1-cyanoethylcarbamoyl]-3-methylbutyl\}morpholine-4-carboxamide 0
                  N-\{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl\}-2-hydroxy-3,5-diiodobenzamide + 8
                  N-desmethylenzalutamide 0
                  N1-(2-cyano-4,6-difluorophenyl)acetamide 0
                  N1-(4-cyanophenyl)acetamide 0
                  N1-[4-(cyanomethyl)phenyl]-4-chlorobenzamide 0
                  NVP-BHS345 0
                  Nilvadipine 5
                  Oxabetrinil 0
                  Pentadecanenitrile 0
                  Pentanenitrile 0
                  Pyraclonil 0
                  SGC-CK2-1 0
                  SL-327 23
                  SU1498 0
                  SureCN668028 0
                  TAK-632 0
                  Tetradecanenitrile 0
                  Tridecanenitrile 0
                  Type III cyanolipid 16:0 ester 0
                  Type III cyanolipid 18:2 ester 0
                  Type III cyanolipid 18:3 ester 0
                  Type III cyanolipid 20:2 ester 0
                  Type IV cyanolipid 16:0 ester 0
                  Type IV cyanolipid 18:2 ester 0
                  Type IV cyanolipid 18:3 ester 0
                  Type IV cyanolipid 20:2 ester 0
                  [(2-chloro-5-methylphenyl)\{6-[(4-\{[(2R)-3-(dimethylamino)-2-hydroxypropyl]oxy\}phenyl)amino]pyrimidin-4-yl\}amino]acetonitrile 0
                  [methyl(oxido)\{1-[6-(trifluoromethyl)pyridin-3-yl]ethyl\}-lambda(6)-sulfanylidene]cyanamide + 17
                  acene nitrile + 0
                  acetamiprid + 56
                  aetokthonotoxin 0
                  alectinib 3
                  aliphatic nitrile + 2200
                  alogliptin 12
                  alpha-(p-Methoxyphenyl)-2-pyridineacrylonitrile 0
                  alpha-(p-Methoxyphenyl)-3-pyridineacrylonitrile 0
                  alpha-cyano-4-hydroxycinnamic acid 4
                  aminopotentidine 0
                  anastrozole + 9
                  anthemis glycoside A 0
                  anthemis glycoside B 0
                  apinocaltamide 0
                  azoxystrobin 722
                  azoxystrobin acid 0
                  baricitinib 9
                  benzonitrile + 7
                  bezitramide 0
                  bosutinib + 22
                  caerulomycinonitrile 0
                  carbonyl cyanide p-trifluoromethoxyphenylhydrazone 71
                  chlorfenapyr 0
                  ciliobrevin D 0
                  cimetidine + 69
                  crisaborole 0
                  crotononitrile 0
                  cyanamide + 117
                  cyanogenic glycoside + 7
                  cyanoguanidine 0
                  cyanopindolol(1+) 0
                  cyanopyrazine 0
                  cyanopyridine + 221
                  cyantraniliprole 0
                  cyazofamid 9
                  cycloprothrin 5
                  cyenopyrafen 0
                  cyfluthrin 98
                  cyhalodiamide 0
                  cyhalothrin + 391
                  cymoxanil 1
                  cypermethrin 776
                  dactolisib 30
                  danuglipron 0
                  delgocitinib 0
                  deltamethrin 0
                  devapamil 0
                  difenoxin + 1
                  dinitrile + 185
                  dioxidanedicarbonitrile 0
                  diphenoxylate + 1
                  enbucrilate 0
                  entacapone + 26
                  enzalutamide 129
                  epithionitrile + 0
                  epsilon-momfluorothrin 0
                  ethyl 2-\{[3-cyano-4-(2-furyl)-6-(2-thienyl)-2-pyridinyl]oxy\}acetate 0
                  fatty nitrile + 0
                  febuxostat 26
                  fenpiclonil 0
                  finafloxacin 0
                  fipronil-desulfinyl 0
                  fipronil-sulfide 0
                  fipronil-sulfone 5
                  flonicamid 0
                  fludioxonil 48
                  flutianil 0
                  fluvalinate + 12
                  gammaGluCys(IAN) 0
                  gammaGluCys(IAN)Glu 0
                  gammaGluCys(IAN)Gly 0
                  glasdegib 0
                  hydrazonomalononitrile + 112
                  hydroxynitrile + 9
                  iFSP1 0
                  indolauxipyr-cyanomethyl 0
                  indole-3-acetonitrile + 0
                  iodocyanopindolol 3
                  ioxynil 3
                  isavuconazole 0
                  isophthalonitrile + 76
                  isotianil 0
                  ketonitrile + 113
                  letrozole 78
                  levosimendan 0
                  linkable pelitinib analogue 0
                  lorlatinib 3
                  methyl (2E)-1,3-benzothiazol-2(3H)-ylidene(cyano)acetate 0
                  methyl 3-cyano-2-phenylpropanoate 0
                  milrinone + 38
                  momelotinib 0
                  monepantel 0
                  montelukast nitrile 0
                  nafadotride 3
                  neratinib 5
                  nirmatrelvir + 0
                  omaveloxolone 6
                  oxomalononitrile + 113
                  pelitinib + 0
                  perampanel + 4
                  periciazine 2
                  phenylacetonitrile + 0
                  piritramide 0
                  prunasin + 7
                  pyrafluprole 0
                  pyrrolidinecarbonitrile + 0
                  ravuconazole 0
                  remdesivir 27
                  ricinine 0
                  rilpivirine 0
                  ruxolitinib + 53
                  sapacitabine 0
                  saxagliptin + 18
                  teriflunomide 43
                  tetracyanoquinodimethane 0
                  tetraniliprole 0
                  thiacloprid + 59
                  tofacitinib + 87
                  toyocamycin 5
                  tralomethrin 1
                  tralopyril + 0
                  trelagliptin 7
                  trilostane 9
                  tyrphostin AG 825 0
                  tyrphostin B42 6
                  vilazodone 0
                  zaleplon 6
                  zuranolone 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19874
        subatomic particle 19872
          composite particle 19872
            hadron 19872
              baryon 19872
                nucleon 19872
                  atomic nucleus 19872
                    atom 19872
                      main group element atom 19811
                        p-block element atom 19811
                          carbon group element atom 19751
                            carbon atom 19748
                              organic molecular entity 19748
                                one-carbon compound 17863
                                  hydrogen cyanide 4795
                                    cyanides 4778
                                      nitrile 4580
                                        ((2-bromo-4-methylphenyl)\{6-[(4-\{[3-(dimethylamino)-2-hydroxypropyl]oxy\}phenyl)amino]pyrimidin-4-yl\}amino)acetonitrile + 0
                                        (+-)-2-(4'-isobutylphenyl)propionitrile 0
                                        (1R)-2-[(cyanomethyl)amino]-1-(\{[2-(difluoromethoxy)benzyl]sulfonyl\}methyl)-2-oxoethyl morpholine-4-carboxylate 0
                                        (1R,5S)-7-[4-(3-cyanophenyl)phenyl]-N-(3-fluorophenyl)-3,6-diazabicyclo[3.1.1]heptane-6-carboxamide 0
                                        (1R,5S)-7-[4-(4-cyanophenyl)phenyl]-N-cyclohexyl-3,6-diazabicyclo[3.1.1]heptane-6-carboxamide 0
                                        (1R,5S)-N-(4-chlorophenyl)-7-[4-(4-cyanophenyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane-6-carboxamide 0
                                        (1S,5R)-7-[4-(3-cyanophenyl)phenyl]-N-(2-methoxyphenyl)-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide 0
                                        (1S,5R)-7-[4-(3-cyanophenyl)phenyl]-N-[4-(trifluoromethyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide 0
                                        (1S,5R)-N-(1,3-benzodioxol-5-yl)-7-[4-(4-cyanophenyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide 0
                                        (2,2,3-trimethylcyclopent-3-en-1-yl)acetonitrile 0
                                        (2-methylphenyl)acetonitrile 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-pyrrolidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3R)-2-[(R)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-pyrrolidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyrrolidin-1-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(3-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2-pyridin-4-ylethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-(pyridin-4-ylmethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(3-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[(4-methoxyphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-piperidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (3S)-2-[(S)-tert-butylsulfinyl]-4-[3-(4-cyanophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2-(1-pyrrolidinyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide 0
                                        (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-phenyl-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-N-(3-fluorophenyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8R,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-N-(4-fluorophenyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8R,9R,10R)-9-[4-(4-cyanophenyl)phenyl]-N-(4-fluorophenyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8R,9R,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8R,9S,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8R,9S,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8S,9R,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8S,9R,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8S,9S,10R)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (8S,9S,10S)-9-[4-(3-cyanophenyl)phenyl]-10-(hydroxymethyl)-N-(2-methoxyphenyl)-1,6-diazabicyclo[6.2.0]decane-6-carboxamide 0
                                        (E)-12-methyltridec-3-enenitrile 0
                                        (E)-13-methyltetradec-3-enenitrile 0
                                        (E)-3-tosylacrylonitrile 0
                                        (E)-tetradec-3-enenitrile 0
                                        (R)-4-hydroxymandelonitrile beta-D-glucoside 0
                                        (S)-4-hydroxymandelonitrile beta-D-glucoside 0
                                        (Z)-12-methyltetradec-3-enenitrile 0
                                        (Z)-12-methyltridec-3-enenitrile 0
                                        (Z)-13-methyltetradec-3-enenitrile 0
                                        (Z)-14-methylpentadec-3-enenitrile 0
                                        (Z)-docos-9-enenitrile 0
                                        (Z)-hexadec-3-enenitrile 0
                                        (Z)-hexadec-9-enenitrile 0
                                        (Z)-octadec-11-enenitrile 0
                                        (Z)-pentadec-3-enenitrile 0
                                        (Z)-tetradec-3-enenitrile 0
                                        (Z)-tetradec-7-enenitrile 0
                                        1,3,5-triazinylamino nitrile + 10
                                        1,3-Di-(octadec-9Z-enoyl)-1-cyano-2-methylene-propane-1,3-diol 0
                                        1,5-diamino-1H-imidazole-4-carbonitrile 0
                                        1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-cyanopyrazin-2-yl)urea 0
                                        1-Cyano-2-hydroxymethylprop-1-ene-3-ol 0
                                        1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-[(2-methylprop-2-en-1-yl)amino]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile + 0
                                        1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile + 50
                                        1-\{[1-(2-amino-3-phenylpropionyl)pyrrolidine-2-carbonyl]amino\}-2-(3-cyanophenyl)ethaneboronic acid 0
                                        1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                                        13-methyltetradecanenitrile 0
                                        2,2'-(5-hydroxy-1,3-phenylene)bis(2-methylpropanenitrile) 0
                                        2,3-bis(4-hydroxyphenyl)propionitrile 46
                                        2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile 0
                                        2,6-diamino-4-(1-phenylethyl)-4H-thiopyran-3,5-dicarbonitrile 0
                                        2,6-dichlorobenzonitrile 2
                                        2-(1-piperidinyl)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile 0
                                        2-(2,6-dihydroxy-3,4-dimethoxycyclohexylidene)acetonitrile 0
                                        2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile + 126
                                        2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl]amino\}-2-(propan-2-yl)pentanenitrile + 1
                                        2-(3-Methoxyphenyl)acetonitrile 0
                                        2-(4-Chloro-2-fluorophenyl)acetonitrile 0
                                        2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile + 0
                                        2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile 0
                                        2-(4-fluorophenyl)-2-[4-[(4-fluorophenyl)-oxomethyl]phenyl]acetonitrile 0
                                        2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile 0
                                        2-(5-amino-4-cyano-1H-imidazol-1-yl)-5-(4-methylpiperazin-1-yl)benzoic acid 0
                                        2-(5-amino-4-cyano-1H-imidazol-1-yl)benzoic acid 0
                                        2-(methylamino)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile 0
                                        2-(thiiran-2-yl)acetonitrile 0
                                        2-Cyanophenol 0
                                        2-Hydroxy-4,6-dimethylnicotinonitrile 0
                                        2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile 0
                                        2-Methoxy-6-(2,2,2-trifluoroethoxy)benzonitrile 0
                                        2-Methyl-6-(trifluoromethyl)nicotinonitrile 0
                                        2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile 0
                                        2-[(4-chlorophenyl)methoxy]-6-methoxybenzonitrile 0
                                        2-[3-(4-cyanoanilino)-1-(dimethylamino)prop-2-enylidene]propanedinitrile 0
                                        2-[3-(diethylamino)propylamino]-4-(methoxymethyl)-6-methyl-3-pyridinecarbonitrile 0
                                        2-\{5-amino-4-[cyano(imino)methyl]-1H-imidazol-1-yl\}-3-phenylpropanoic acid 0
                                        2-\{[3-(Dimethylamino)propyl]amino\}-6-fluorobenzonitrile 0
                                        2-amino-2-phenylacetonitrile 0
                                        2-amino-3-cyano-7-(dimethylamino)-4-(2-methoxyphenyl)-4H-chromene 0
                                        2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene 1
                                        2-amino-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzonitrile 0
                                        2-amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrile 0
                                        2-cyano-3-cyclopropyl-1-(2-mesyl-4-trifluoromethylphenyl)propan-1,3-dione 0
                                        2-cyano-N-[1-(2,4-dichlorophenyl)ethyl]-3,3-dimethylbutanamide + 0
                                        2-fluoro-6-(4-methoxyphenoxy)benzonitrile 0
                                        2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate + 0
                                        2-methyl-Pentanedinitrile 0
                                        2-oxo-4,6-dithiophen-2-yl-1H-pyridine-3-carbonitrile 0
                                        2-thienylacetonitrile 0
                                        3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin 1
                                        3-(5-\{[4-(aminomethyl)piperidin-1-yl]methyl\}-1H-indol-2-yl)-1H-indazole-6-carbonitrile 0
                                        3-(\{[(2S)-5-oxopyrrolidin-2-yl]methyl\}sulfonyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-L-alanin[N-(1-cyanocyclopropyl)]amide 0
                                        3-Ethylbenzonitrile 0
                                        3-O-14,15-Eicosylenoyl-1-cyano-2-methyl-1,2-propene 0
                                        3-O-ethylentacapone 0
                                        3-O-methylentacapone 0
                                        3-[(4R,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4S,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4S,5S)-5-[(dimethylamino)methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4S,5S)-5-[(dimethylamino)methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[(4S,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        3-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-(piperidine-1-carbonyl)-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        3-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[oxo(1-piperidinyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        3-[4-[(1R,5S)-3-(2-methylphenyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(1R,5S)-3-(phenylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(1R,5S)-3-[1,3-benzodioxol-5-yl(oxo)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(1R,5S)-3-[oxo(3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(1R,5S)-6-[(2-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(1S,5R)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(1S,5R)-3-(4-oxazolylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(1S,5R)-3-[(2-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        3-[4-[(2R,3R)-6-acetyl-2-(hydroxymethyl)-1-(3,3,3-trifluoropropyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                                        3-[4-[(2S,3R)-6-acetyl-2-(hydroxymethyl)-1-(3,3,3-trifluoropropyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                                        3-[4-[(2S,3S)-6-acetyl-2-(hydroxymethyl)-1-(3,3,3-trifluoropropyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-(1-oxo-2-phenylethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-(1-oxo-2-pyridin-4-ylethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-[1-oxo-2-(3-pyridinyl)ethyl]-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-methylsulfonyl-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9R,10R)-6-(benzenesulfonyl)-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9R,10R)-6-ethylsulfonyl-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9R,10S)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8R,9S,10S)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8S,9R,10R)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8S,9S,10R)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[4-[(8S,9S,10S)-6-[(2-fluorophenyl)methyl]-10-(hydroxymethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        3-[di(propan-2-yl)phosphorylmethyl]benzonitrile 0
                                        3-\{[(9-cyano-10-methyl-9,10-dihydroacridin-9-yl)carbonyl]amino\}propanoic acid 0
                                        3-amino-7-(4-methylpiperazin-1-yl)-9-oxo-9H-imidazo[1,2-a]indole-2-carbonitrile 0
                                        3-amino-9-oxo-9H-imidazo[1,2-a]indole-2-carbonitrile 0
                                        3-cyano-2-butanone 0
                                        3-cyano-2-pyridone 0
                                        3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone 0
                                        3-hydroxy-3-phenylpropionitrile 0
                                        3-hydroxypent-4-ene nitrile 0
                                        3-phenylpropionitrile + 0
                                        3-pyridinecarbonitrile 0
                                        4,4'-dimethoxy[1,1'-biphenyl]-2-carbonitrile 0
                                        4,6-dimethyl-2-[3-(4-morpholinyl)propylamino]-3-pyridinecarbonitrile 0
                                        4-(1H-imidazol-1-ylmethyl)benzonitrile 0
                                        4-(2-Hydroxyethyl)benzonitrile 0
                                        4-(2-furyl)-2-oxo-6-(2-thienyl)-1,2-dihydro-3-pyridinecarbonitrile 0
                                        4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile + 33
                                        4-(Trifluoromethoxy)phenylacetonitrile 0
                                        4-(Trifluoromethyl)nicotinonitrile 0
                                        4-(\{(2R,5S)-2,5-dimethyl-4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperazin-1-yl\}carbonyl)benzonitrile 0
                                        4-(\{4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl\}amino)benzonitrile 0
                                        4-(\{5-bromo-2-[(4-cyanophenyl)amino]-6-(hydroxymethyl)pyrimidin-4-yl\}oxy)-3,5-dimethylbenzonitrile 0
                                        4-(\{6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-sulfanyl-1H-1,2,4-triazol-1-yl)propyl]pyridin-3-yl\}oxy)benzonitrile + 0
                                        4-(\{6-[2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-sulfanylidene-2,5-dihydro-1H-1,2,4-triazol-1-yl)propyl]pyridin-3-yl\}oxy)benzonitrile + 0
                                        4-(\{6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl\}oxy)-3,5-dimethylbenzonitrile 0
                                        4-(methoxymethyl)-6-methyl-2-(2-methylanilino)-3-pyridinecarbonitrile 0
                                        4-(morpholinocarbothioyl)benzonitrile 0
                                        4-Amino-3-chlorobenzonitrile 0
                                        4-Chlorobenzonitrile 0
                                        4-Fluorobenzonitrile 0
                                        4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile 0
                                        4-[(4R,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4R,5R)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4R,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4R,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4R,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4R,5S)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5R)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5R)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5R)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5R)-5-[[cyclopropylmethyl(methyl)amino]methyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-(methylaminomethyl)-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[(4S,5S)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-5-[[methyl(2-pyridinylmethyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-8-yl]benzonitrile 0
                                        4-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[(4-methyl-1-piperazinyl)-oxomethyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        4-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[4-morpholinyl(oxo)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        4-[3-[(3R)-2-[(R)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[oxo(1-piperidinyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        4-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-(piperidine-1-carbonyl)-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        4-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[(4-methyl-1-piperazinyl)-oxomethyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        4-[3-[(3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-6-[4-morpholinyl(oxo)methyl]-1,3-dihydropyrrolo[3,4-c]pyridin-4-yl]phenyl]benzonitrile 0
                                        4-[4-[(1R,5S)-3-(2-methylphenyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1R,5S)-6-[(3-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-(1-oxo-2-phenylethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-(4-fluorophenyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-(4-oxazolylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-(phenylmethyl)sulfonyl-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-[(2-methoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-[(3,5-dimethoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-[cyclohexyl(oxo)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-3-[oxo(pyridin-4-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(1S,5R)-6-(1,3-benzodioxol-5-ylmethyl)-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(2R,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                                        4-[4-[(2S,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                                        4-[4-[(2S,3S)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7R,8R)-4-[cyclohexyl(oxo)methyl]-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7R,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7R,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7R,8S)-4-[cyclohexyl(oxo)methyl]-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7R,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7R,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7S,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7S,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7S,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6R,7S,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7R,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7R,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7R,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7R,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7S,8R)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7S,8R)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7S,8S)-8-(hydroxymethyl)-2-oxo-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(6S,7S,8S)-8-(hydroxymethyl)-2-oxo-4-(1-oxopropyl)-1,4-diazabicyclo[4.2.0]octan-7-yl]phenyl]benzonitrile 0
                                        4-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-(1-oxo-2-phenylethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile 0
                                        4-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]benzonitrile 0
                                        4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrile 0
                                        4-\{2-[(2-hydroxybenzyl)amino]ethyl\}-2,5-dimethoxybenzonitrile 0
                                        4-chlorophenylacetonitrile 0
                                        4-cyanobenzoyl chloride 0
                                        4-hydroxychlorothalonil 0
                                        4-phenyl-3-furoxancarbonitrile 3
                                        5,7-dibromo-indole-3-carbonitrile 0
                                        5-(methylsulfanyl)-2-(thiophen-2-yl)-3-(trifluoromethyl)pyridine-4-carbonitrile 0
                                        5-(methylsulfanyl)pentanenitrile 0
                                        5-Chloro-2-hydroxy-4,6-dimethylnicotinonitrile 0
                                        5-\{N-[4-(4-cyanostyryl)phenyl]-N-methylamino\}pentanoic acid 0
                                        5-allyl-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 0
                                        5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile + 1160
                                        5-amino-1-[3-fluoro-4-(morpholin-4-yl)phenyl]imidazole-4-carbonitrile 0
                                        5-amino-1-anilinoimidazole-4-carbonitrile 0
                                        5-amino-1-benzoylimidazole-4-carbonitrile 0
                                        5-amino-1-formylimidazole-4-carbonitrile 0
                                        5-amino-4-cyano-1H-imidazole-1-carboxamide 0
                                        5-cyano-N-[5-(hydroxymethyl)-2-(4-methylpiperidin-1-yl)phenyl]furan-2-carboxamide 0
                                        5-ethyl-4,6-dimethyl-2-sulfanylidene-1H-pyridine-3-carbonitrile 0
                                        5-hydroxy-2-(4-hydroxyphenyl)-1-benzofuran-7-carbonitrile 0
                                        5-methylsulfinylpentyl nitrile 0
                                        6-(2-furyl)-2-hydroxy-4-(2-thienyl)nicotinonitrile 0
                                        6-(2-furyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile 0
                                        6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)ethyl]-9H-purine-2-carbonitrile 0
                                        6-amino-1-(4-chlorophenyl)-2-oxo-4-(1,2,4-triazol-1-ylmethyl)-5-pyrimidinecarbonitrile 0
                                        6-amino-3-(methoxymethyl)-5-spiro[2H-pyrano[2,3-c]pyrazole-4,4'-thiane]carbonitrile 0
                                        6-hydroxy-1-(3-hydroxypropyl)-4-methyl-2-oxo-5-(1-piperidinylmethyl)-3-pyridinecarbonitrile 0
                                        6-methoxynaphthalene-1-carbonitrile 0
                                        6-methyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile 0
                                        6-tert-butyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile 0
                                        7-(Methylthio)heptanenitrile 0
                                        7-cyano-7-deazaguanine 0
                                        8-(Methylthio)octanenitrile 0
                                        9-(Methylthio)nonanenitrile 0
                                        9-cyclopentyl-6-\{2-[3-(4-methylpiperazin-1-yl)propoxy]phenylamino\}-9H-purine-2-carbonitrile 0
                                        AM6545 14
                                        AZ3451 0
                                        AZD1080 0
                                        BAY-826 0
                                        BAY11-7085 0
                                        BMS-214662 0
                                        BPDZ 711 0
                                        Bromochloroacetonitrile 5
                                        CCCP 46
                                        CNDAC + 0
                                        CT3 0
                                        Chloroacetonitrile 14
                                        Chlorphoxim 0
                                        Citalopram alcohol 0
                                        Citalopram aldehyde 0
                                        Citalopram propionic acid 0
                                        Cyanofenphos 3
                                        Cyanthoate 0
                                        Cyometrinil 0
                                        Cys(IAN)-Gly 0
                                        D617 0
                                        Dodecanenitrile 0
                                        Fe(CN)2 0
                                        GS-441524 + 27
                                        GS-441524 monophosphate 0
                                        GS-443902 0
                                        Girgensonine 0
                                        Hexadecanenitrile 0
                                        Hexanenitrile 0
                                        Isoamyl cyanide 0
                                        L-778,123 (free base) + 0
                                        L-Cys(IAN) 0
                                        LFM-A13 0
                                        LLY-507 8
                                        Methylacrylonitrile 2
                                        Mirabilene E isonitrile 0
                                        N-(2-[(2-aminoethyl)(methyl)amino]-5-\{[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino\}phenyl)acetamide 0
                                        N-(2-cyano-3-methylbutan-2-yl)-2-(2,4-dichlorophenoxy)propanamide + 0
                                        N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide 0
                                        N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide 0
                                        N-[3-cyano-6-(3-piperidin-1-ylpropanoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl]naphthalene-1-carboxamide 0
                                        N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide + 203
                                        N-[[(2R,3S,4S)-1-acetyl-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-N-methylacetamide 0
                                        N-[[(2S,3R,4R)-1-acetyl-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-N-methylacetamide 0
                                        N-[[(2S,3R,4S)-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]cyclobutanecarboxamide 0
                                        N-[[(2S,3S,4R)-3-[4-(3-cyanophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-(dimethylamino)acetamide 0
                                        N-[[(4R,5R)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[[(4R,5R)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[[(4R,5S)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[[(4R,5S)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[[(4S,5R)-8-(3-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-N-methylcyclopropanecarboxamide 0
                                        N-[[(4S,5R)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[[(4S,5R)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[[(4S,5S)-8-(3-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-N-methylcyclopropanecarboxamide 0
                                        N-[[(4S,5S)-8-(4-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[[(4S,5S)-8-(4-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^\{6\},2-benzoxathiazocin-5-yl]methyl]-2-methoxy-N-methylacetamide 0
                                        N-[cyano(2-thienyl)methyl]-4-ethyl-2-(ethylamino)-1,3-thiazole-5-carboxamide + 0
                                        N-\{(1S)-1-[(1R)-2-benzyloxy-1-cyanoethylcarbamoyl]-3-methylbutyl\}morpholine-4-carboxamide 0
                                        N-\{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl\}-2-hydroxy-3,5-diiodobenzamide + 8
                                        N-desmethylenzalutamide 0
                                        N1-(2-cyano-4,6-difluorophenyl)acetamide 0
                                        N1-(4-cyanophenyl)acetamide 0
                                        N1-[4-(cyanomethyl)phenyl]-4-chlorobenzamide 0
                                        NVP-BHS345 0
                                        Nilvadipine 5
                                        Oxabetrinil 0
                                        Pentadecanenitrile 0
                                        Pentanenitrile 0
                                        Pyraclonil 0
                                        SGC-CK2-1 0
                                        SL-327 23
                                        SU1498 0
                                        SureCN668028 0
                                        TAK-632 0
                                        Tetradecanenitrile 0
                                        Tridecanenitrile 0
                                        Type III cyanolipid 16:0 ester 0
                                        Type III cyanolipid 18:2 ester 0
                                        Type III cyanolipid 18:3 ester 0
                                        Type III cyanolipid 20:2 ester 0
                                        Type IV cyanolipid 16:0 ester 0
                                        Type IV cyanolipid 18:2 ester 0
                                        Type IV cyanolipid 18:3 ester 0
                                        Type IV cyanolipid 20:2 ester 0
                                        [(2-chloro-5-methylphenyl)\{6-[(4-\{[(2R)-3-(dimethylamino)-2-hydroxypropyl]oxy\}phenyl)amino]pyrimidin-4-yl\}amino]acetonitrile 0
                                        [methyl(oxido)\{1-[6-(trifluoromethyl)pyridin-3-yl]ethyl\}-lambda(6)-sulfanylidene]cyanamide + 17
                                        acene nitrile + 0
                                        acetamiprid + 56
                                        aetokthonotoxin 0
                                        alectinib 3
                                        aliphatic nitrile + 2200
                                        alogliptin 12
                                        alpha-(p-Methoxyphenyl)-2-pyridineacrylonitrile 0
                                        alpha-(p-Methoxyphenyl)-3-pyridineacrylonitrile 0
                                        alpha-cyano-4-hydroxycinnamic acid 4
                                        aminopotentidine 0
                                        anastrozole + 9
                                        anthemis glycoside A 0
                                        anthemis glycoside B 0
                                        apinocaltamide 0
                                        azoxystrobin 722
                                        azoxystrobin acid 0
                                        baricitinib 9
                                        benzonitrile + 7
                                        bezitramide 0
                                        bosutinib + 22
                                        caerulomycinonitrile 0
                                        carbonyl cyanide p-trifluoromethoxyphenylhydrazone 71
                                        chlorfenapyr 0
                                        ciliobrevin D 0
                                        cimetidine + 69
                                        crisaborole 0
                                        crotononitrile 0
                                        cyanamide + 117
                                        cyanogenic glycoside + 7
                                        cyanoguanidine 0
                                        cyanopindolol(1+) 0
                                        cyanopyrazine 0
                                        cyanopyridine + 221
                                        cyantraniliprole 0
                                        cyazofamid 9
                                        cycloprothrin 5
                                        cyenopyrafen 0
                                        cyfluthrin 98
                                        cyhalodiamide 0
                                        cyhalothrin + 391
                                        cymoxanil 1
                                        cypermethrin 776
                                        dactolisib 30
                                        danuglipron 0
                                        delgocitinib 0
                                        deltamethrin 0
                                        devapamil 0
                                        difenoxin + 1
                                        dinitrile + 185
                                        dioxidanedicarbonitrile 0
                                        diphenoxylate + 1
                                        enbucrilate 0
                                        entacapone + 26
                                        enzalutamide 129
                                        epithionitrile + 0
                                        epsilon-momfluorothrin 0
                                        ethyl 2-\{[3-cyano-4-(2-furyl)-6-(2-thienyl)-2-pyridinyl]oxy\}acetate 0
                                        fatty nitrile + 0
                                        febuxostat 26
                                        fenpiclonil 0
                                        finafloxacin 0
                                        fipronil-desulfinyl 0
                                        fipronil-sulfide 0
                                        fipronil-sulfone 5
                                        flonicamid 0
                                        fludioxonil 48
                                        flutianil 0
                                        fluvalinate + 12
                                        gammaGluCys(IAN) 0
                                        gammaGluCys(IAN)Glu 0
                                        gammaGluCys(IAN)Gly 0
                                        glasdegib 0
                                        hydrazonomalononitrile + 112
                                        hydroxynitrile + 9
                                        iFSP1 0
                                        indolauxipyr-cyanomethyl 0
                                        indole-3-acetonitrile + 0
                                        iodocyanopindolol 3
                                        ioxynil 3
                                        isavuconazole 0
                                        isophthalonitrile + 76
                                        isotianil 0
                                        ketonitrile + 113
                                        letrozole 78
                                        levosimendan 0
                                        linkable pelitinib analogue 0
                                        lorlatinib 3
                                        methyl (2E)-1,3-benzothiazol-2(3H)-ylidene(cyano)acetate 0
                                        methyl 3-cyano-2-phenylpropanoate 0
                                        milrinone + 38
                                        momelotinib 0
                                        monepantel 0
                                        montelukast nitrile 0
                                        nafadotride 3
                                        neratinib 5
                                        nirmatrelvir + 0
                                        omaveloxolone 6
                                        oxomalononitrile + 113
                                        pelitinib + 0
                                        perampanel + 4
                                        periciazine 2
                                        phenylacetonitrile + 0
                                        piritramide 0
                                        prunasin + 7
                                        pyrafluprole 0
                                        pyrrolidinecarbonitrile + 0
                                        ravuconazole 0
                                        remdesivir 27
                                        ricinine 0
                                        rilpivirine 0
                                        ruxolitinib + 53
                                        sapacitabine 0
                                        saxagliptin + 18
                                        teriflunomide 43
                                        tetracyanoquinodimethane 0
                                        tetraniliprole 0
                                        thiacloprid + 59
                                        tofacitinib + 87
                                        toyocamycin 5
                                        tralomethrin 1
                                        tralopyril + 0
                                        trelagliptin 7
                                        trilostane 9
                                        tyrphostin AG 825 0
                                        tyrphostin B42 6
                                        vilazodone 0
                                        zaleplon 6
                                        zuranolone 0
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