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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases activity multiple interactions |
ISO |
telmisartan results in decreased activity of ABCB11 protein telmisartan inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] |
CTD |
PMID:20829430 PMID:23956101 PMID:24014644 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
multiple interactions increases expression |
ISO |
PPARG mutant form inhibits the reaction [telmisartan results in increased expression of ABCG1 mRNA] |
CTD |
PMID:22124178 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Ace |
angiotensin I converting enzyme |
decreases expression multiple interactions |
EXP |
Telmisartan results in decreased expression of ACE mRNA; Telmisartan results in decreased expression of ACE protein Telmisartan inhibits the reaction [Pregabalin results in increased expression of ACE protein] |
CTD |
PMID:19171132 PMID:25973029 PMID:29909460 PMID:31629013 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin converting enzyme 2 |
multiple interactions increases expression decreases expression decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein] Telmisartan results in increased expression of ACE2 mRNA; Telmisartan results in increased expression of ACE2 protein Telmisartan results in decreased expression of ACE2 mRNA; Telmisartan results in decreased expression of ACE2 protein Telmisartan inhibits the reaction [Pregabalin results in decreased expression of ACE2 protein] telmisartan decreases expression of mRNA in mandible of rats with periodontal disease |
CTD RGD |
PMID:21381899 PMID:25973029 PMID:28656296 PMID:29909460 PMID:31629013 PMID:33364953 More...
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RGD:329956421 |
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Ache |
acetylcholinesterase |
multiple interactions |
ISO |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein] |
CTD |
PMID:23060470 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
decreases activity |
EXP |
telmisartan decreases enzyme activity of Trap, Acp5 in serum of rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO |
telmisartan results in increased expression of ADIPOQ mRNA telmisartan results in increased expression of ADIPOQ protein |
CTD |
PMID:19730415 PMID:20555330 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Agt |
angiotensinogen |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein] Telmisartan inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA]; Telmisartan inhibits the reaction [AGT protein results in decreased expression of SYP protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of AGTR1A mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of CRH protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of FOS protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of IL1B protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; Telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Telmisartan inhibits the reaction [AGT protein results in increased ubiquitination of SYP protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of AGT protein]; Telmisartan inhibits the reaction [Diatrizoate results in increased expression of AGT protein]; Telmisartan inhibits the reaction [Iohexol results in increased expression of AGT protein]; Telmisartan inhibits the reaction [Pregabalin results in decreased expression of AGT protein] telmisartan results in decreased expression of AGT mRNA; telmisartan results in decreased expression of AGT protein |
CTD |
PMID:9533614 PMID:17620961 PMID:18487452 PMID:19171132 PMID:19289654 PMID:19292980 PMID:19452295 PMID:19706694 PMID:31629013 PMID:33872574 PMID:34339004 More...
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Agtr1a |
angiotensin II receptor, type 1a |
affects binding increases expression multiple interactions decreases expression decreases expression |
EXP ISO |
telmisartan binds to AGTR1 protein telmisartan results in increased expression of AGTR1 mRNA Telmisartan binds to and results in decreased activity of AGTR1 protein; Telmisartan inhibits the reaction [AGT protein results in increased expression of AGTR1A mRNA]; Telmisartan inhibits the reaction [Daunorubicin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein] telmisartan binds to and results in decreased activity of AGTR1 protein telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein] telmisartan results in decreased expression of AGTR1A mRNA telmisartan decreases expression of mRNA in mandible of rats with periodontal disease |
CTD RGD |
PMID:8220885 PMID:9533614 PMID:9728324 PMID:17620961 PMID:19171132 PMID:19706694 PMID:20888384 PMID:21381899 PMID:21557540 PMID:31629013 PMID:33364953 More...
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RGD:329956421 |
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Agtr1b |
angiotensin II receptor, type 1b |
multiple interactions |
ISO |
telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] |
CTD |
PMID:17620961 |
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NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
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G |
Agtr2 |
angiotensin II receptor, type 2 |
increases expression |
EXP |
telmisartan increases expression of mRNA in mandible of rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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G |
Ahr |
aryl hydrocarbon receptor |
increases activity |
EXP |
Telmisartan results in increased activity of AHR protein |
CTD |
PMID:28728110 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Alb |
albumin |
affects expression multiple interactions |
ISO |
telmisartan affects the expression of ALB protein modified form Telmisartan affects the reaction [LEPR protein affects the abundance of ALB protein] |
CTD |
PMID:16671338 PMID:34464088 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
increases activity multiple interactions |
EXP |
telmisartan increases enzyme activity of Alpl in serum of rats with periodontal disease Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of ALPL protein] |
CTD RGD |
PMID:27269004 PMID:33364953 |
RGD:329956421 |
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Ang2 |
angiogenin, ribonuclease A family, member 2 |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of ANG2 protein] |
CTD |
PMID:23750309 |
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NCBI chr15:24,398,330...24,415,909
Ensembl chr15:24,398,419...24,398,922
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA] |
CTD |
PMID:24831514 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA] |
CTD |
PMID:24831514 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein] |
CTD |
PMID:23747572 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Cacna1g |
calcium voltage-gated channel subunit alpha1 G |
multiple interactions decreases expression |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [telmisartan results in decreased expression of CACNA1G mRNA]; SB 203580 inhibits the reaction [telmisartan results in decreased expression of CACNA1G mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA] |
CTD |
PMID:19292980 |
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NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
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G |
Cacna1h |
calcium voltage-gated channel subunit alpha1 H |
multiple interactions decreases expression |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [telmisartan results in decreased expression of CACNA1H mRNA]; SB 203580 inhibits the reaction [telmisartan results in decreased expression of CACNA1H mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA] |
CTD |
PMID:19292980 |
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NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
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G |
Casp3 |
caspase 3 |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP3 protein] telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; telmisartan inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein] Telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; Telmisartan inhibits the reaction [Diatrizoate results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Iohexol results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of CASP3 protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of CASP3]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA] Telmisartan results in decreased expression of CASP3 protein |
CTD |
PMID:18565324 PMID:19452295 PMID:21620867 PMID:21819444 PMID:22750630 PMID:24831514 PMID:26439596 PMID:27269004 PMID:29909460 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cat |
catalase |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [arsenite results in decreased activity of CAT protein]; Telmisartan inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] |
CTD |
PMID:23750309 PMID:26929000 PMID:34339004 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] telmisartan results in decreased expression of CCL2 protein |
CTD |
PMID:17922026 PMID:22124178 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
decreases response to substance |
ISO |
telmisartan results in decreased susceptibility to CCL5 protein |
CTD |
PMID:18158351 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
decreases expression |
EXP |
telmisartan results in decreased expression of CCR2 mRNA |
CTD |
PMID:17922026 |
|
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Cd36 |
CD36 molecule |
increases expression multiple interactions |
ISO |
telmisartan results in increased expression of CD36 mRNA PPARG mutant form inhibits the reaction [telmisartan results in increased expression of CD36 mRNA]; T 0070907 inhibits the reaction [telmisartan results in increased expression of CD36 mRNA] |
CTD |
PMID:22124178 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
EXP |
telmisartan inhibits the reaction [TNF protein promotes the reaction [CEBPB protein binds to IL6 promoter]] |
CTD |
PMID:19289654 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Crh |
corticotropin releasing hormone |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [AGT protein results in increased expression of CRH protein] |
CTD |
PMID:33872574 |
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NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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G |
Crp |
C-reactive protein |
decreases expression |
ISO |
telmisartan results in decreased expression of CRP protein |
CTD |
PMID:20555330 |
|
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Ctsk |
cathepsin K |
decreases expression |
EXP |
telmisartan decreases expression of mRNA in mandible of rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases response to substance |
ISO |
PPARG protein promotes the reaction [telmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]]; telmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein] telmisartan results in decreased susceptibility to CXCL12 protein |
CTD |
PMID:18158351 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
decreases expression |
EXP |
telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cyba |
cytochrome b-245 alpha chain |
decreases expression multiple interactions |
ISO EXP |
telmisartan results in decreased expression of CYBA mRNA; telmisartan results in decreased expression of CYBA protein telmisartan inhibits the reaction [Daunorubicin results in increased expression of CYBA protein] |
CTD |
PMID:16141465 PMID:19171132 PMID:21054405 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein] telmisartan results in decreased expression of CYBB mRNA Telmisartan inhibits the reaction [Glucose results in increased expression of CYBB mRNA]; Telmisartan inhibits the reaction [Glucose results in increased expression of CYBB protein] Telmisartan inhibits the reaction [arsenite results in increased expression of CYBB mRNA] |
CTD |
PMID:19171132 PMID:21381899 PMID:34339004 PMID:34464088 |
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NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA] |
CTD |
PMID:24831514 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
decreases activity |
ISO |
Telmisartan results in decreased activity of CYP2J2 protein |
CTD |
PMID:30965050 |
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NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
decreases expression |
EXP |
telmisartan results in decreased expression of DDIT3 protein |
CTD |
PMID:19102871 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Edn1 |
endothelin 1 |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Daunorubicin results in increased expression of EDN1 protein] |
CTD |
PMID:20888384 |
|
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Ednra |
endothelin receptor type A |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Daunorubicin results in increased expression of EDNRA protein] |
CTD |
PMID:20888384 |
|
NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
Ednrb |
endothelin receptor type B |
multiple interactions |
EXP |
telmisartan promotes the reaction [Daunorubicin results in increased expression of EDNRB protein] |
CTD |
PMID:20888384 |
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NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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G |
Faslg |
Fas ligand |
multiple interactions |
ISO EXP |
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of FASL protein] telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of FASLG protein] |
CTD |
PMID:21620867 PMID:21819444 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
EXP |
telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of FN1 protein] |
CTD |
PMID:19706694 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [AGT protein results in increased expression of FOS protein] |
CTD |
PMID:33872574 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Gdnf |
glial cell derived neurotrophic factor |
multiple interactions |
ISO |
Telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF mRNA]; Telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF protein] |
CTD |
PMID:23747572 |
|
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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G |
Gfap |
glial fibrillary acidic protein |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein] Telmisartan results in decreased expression of GFAP protein |
CTD |
PMID:23747572 PMID:29909460 |
|
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of GGT1 protein] |
CTD |
PMID:23750309 |
|
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions |
ISO |
Telmisartan inhibits the reaction [Dibutyl Phthalate results in increased expression of GJA1 protein] |
CTD |
PMID:37356649 |
|
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of GOT1 protein] |
CTD |
PMID:27269004 |
|
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of GPT protein] |
CTD |
PMID:26929000 PMID:27269004 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gsr |
glutathione-disulfide reductase |
decreases activity multiple interactions |
EXP |
Telmisartan results in decreased activity of GSR protein Telmisartan inhibits the reaction [arsenite results in decreased activity of GSR protein] |
CTD |
PMID:34339004 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Hgf |
hepatocyte growth factor |
increases expression |
ISO |
telmisartan results in increased expression of HGF mRNA |
CTD |
PMID:21479465 |
|
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
decreases expression |
EXP |
telmisartan results in decreased expression of HSPA5 protein |
CTD |
PMID:19102871 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Ibsp |
integrin-binding sialoprotein |
increases expression |
EXP |
telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA] telmisartan inhibits the reaction [Daunorubicin results in increased expression of ICAM1 protein] |
CTD |
PMID:17724226 PMID:20888384 PMID:22124178 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il10 |
interleukin 10 |
multiple interactions increases expression decreases expression |
EXP |
telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein] Telmisartan results in increased expression of IL10 protein telmisartan decreases expression of protein in mandible of WKY rats with periodontal disease |
CTD RGD |
PMID:24831514 PMID:29909460 PMID:33364953 |
RGD:329956421 |
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1b |
interleukin 1 beta |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] Telmisartan inhibits the reaction [AGT protein results in increased expression of IL1B protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of IL1B protein] telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease |
CTD RGD |
PMID:22124178 PMID:33872574 PMID:34339004 PMID:33364953 |
RGD:329956421 |
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]; telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein] 2-chloro-5-nitrobenzanilide inhibits the reaction [Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; Telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [TNF protein promotes the reaction [CEBPB protein binds to IL6 promoter]]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein] telmisartan results in decreased expression of IL6 mRNA Telmisartan results in decreased expression of IL6 protein |
CTD |
PMID:19289654 PMID:21479465 PMID:22124178 PMID:29909460 PMID:34339004 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
increases expression |
EXP |
Telmisartan results in increased expression of INS1 protein |
CTD |
PMID:19171132 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
decreases expression |
ISO |
telmisartan results in decreased expression of INS protein |
CTD |
PMID:15892894 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
[Atorvastatin co-treated with Telmisartan] results in decreased expression of IRAK1 mRNA |
CTD |
PMID:20524934 |
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NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Kcnn4 |
potassium calcium-activated channel subfamily N member 4 |
decreases expression |
ISO |
telmisartan decreases expression of KCNN4 mRNA and protein in CD4-positive alpha-beta T cell |
RGD |
PMID:26502942 |
RGD:329955577 |
NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
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G |
Lepr |
leptin receptor |
multiple interactions |
ISO |
Telmisartan affects the reaction [LEPR protein affects the abundance of ALB protein]; Telmisartan affects the reaction [LEPR protein affects the expression of OCLN mRNA] |
CTD |
PMID:34464088 |
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NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lipe |
lipase E, hormone sensitive type |
multiple interactions increases expression |
ISO |
PPARD promotes the reaction [telmisartan results in increased expression of LIPE protein] |
CTD |
PMID:20176998 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:22124178 PMID:33872574 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions decreases phosphorylation |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] telmisartan results in decreased phosphorylation of MAPK14 protein |
CTD |
PMID:19292980 PMID:22124178 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] Telmisartan inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:22124178 PMID:33872574 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapkapk2 |
MAPK activated protein kinase 2 |
multiple interactions |
ISO |
telmisartan inhibits the reaction [Streptozocin results in increased expression of MAPKAPK2 protein modified form] |
CTD |
PMID:21381899 |
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NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
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G |
Mas1 |
MAS1 proto-oncogene, G protein-coupled receptor |
multiple interactions increases expression |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein] Telmisartan results in increased expression of MAS1 protein Telmisartan inhibits the reaction [Pregabalin results in decreased expression of MAS1 protein] |
CTD |
PMID:21381899 PMID:28656296 PMID:31629013 |
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NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
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G |
Mir146a |
microRNA 146a |
multiple interactions |
ISO EXP |
[Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146A telmisartan inhibits the reaction [ischemia-reperfusion injury increases expression of Mir146a miRNA in kidney] |
CTD RGD |
PMID:20524934 PMID:27760486 |
RGD:155882556 |
NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
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G |
Mir146b |
microRNA 146b |
multiple interactions |
ISO |
[Atorvastatin co-treated with Telmisartan] results in decreased expression of MIR146B |
CTD |
PMID:20524934 |
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NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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G |
Mir320a |
microRNA 320a |
multiple interactions |
EXP |
telmisartan inhibits the reaction [ischemia-reperfusion injury increases expression of Mir320a miRNA in kidney] |
RGD |
PMID:27760486 |
RGD:155882556 |
NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases expression decreases expression |
EXP |
telmisartan results in decreased expression of MMP2 protein telmisartan decreases expression of mRNA in mandible of WKY rats with periodontal disease |
CTD RGD |
PMID:21054405 PMID:33364953 |
RGD:329956421 |
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases expression |
EXP |
telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein] Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased activity of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] |
CTD |
PMID:23060470 PMID:24831514 PMID:26439596 PMID:26929000 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mylk |
myosin light chain kinase |
multiple interactions |
ISO |
MYLK protein inhibits the reaction [Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN mRNA]]; Telmisartan inhibits the reaction [Glucose results in increased expression of MYLK mRNA]; Telmisartan inhibits the reaction [Glucose results in increased expression of MYLK protein] |
CTD |
PMID:34464088 |
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NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF1 protein] telmisartan results in decreased expression of NCF1 mRNA; telmisartan results in decreased expression of NCF1 protein Telmisartan results in decreased expression of NCF1 mRNA; Telmisartan results in decreased expression of NCF1 protein telmisartan inhibits the reaction [Daunorubicin results in increased expression of NCF1 protein] |
CTD |
PMID:16141465 PMID:19171132 PMID:21054405 PMID:21381899 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF2 protein] telmisartan results in decreased expression of NCF2 mRNA; telmisartan results in decreased expression of NCF2 protein telmisartan inhibits the reaction [Daunorubicin results in increased expression of NCF2 protein] |
CTD |
PMID:16141465 PMID:21054405 PMID:21381899 |
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NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of NFKB1 protein] |
CTD |
PMID:21620867 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA]]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA] |
CTD |
PMID:22124178 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO EXP |
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of NOS2 protein]; telmisartan inhibits the reaction [sodium arsenite results in increased expression of NOS2 protein] Telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of NOS2 protein]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of NOS2 protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of NOS2]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA] |
CTD |
PMID:21620867 PMID:21819444 PMID:22750630 PMID:24831514 PMID:26439596 PMID:26929000 PMID:27269004 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions increases expression increases phosphorylation |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in increased expression of NOS3 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in increased phosphorylation of NOS3 protein] |
CTD |
PMID:21156825 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nox4 |
NADPH oxidase 4 |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Daunorubicin results in increased expression of NOX4 protein] |
CTD |
PMID:21054405 |
|
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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G |
Nphs1 |
NPHS1 adhesion molecule, nephrin |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [Daunorubicin results in decreased expression of NPHS1 protein] |
CTD |
PMID:20888384 |
|
NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
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G |
Nppb |
natriuretic peptide B |
affects expression decreases expression multiple interactions |
ISO EXP |
telmisartan affects the expression of NPPB protein telmisartan results in decreased expression of NPPB protein Telmisartan inhibits the reaction [Pregabalin results in increased expression of NPPB protein] |
CTD |
PMID:16671338 PMID:18712048 PMID:31629013 |
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NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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G |
Ocln |
occludin |
multiple interactions |
ISO |
MYLK protein inhibits the reaction [Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN mRNA]]; Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN mRNA]; Telmisartan inhibits the reaction [Glucose results in decreased expression of OCLN protein] Telmisartan affects the reaction [LEPR protein affects the expression of OCLN mRNA] |
CTD |
PMID:34464088 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Olr1 |
oxidized low density lipoprotein receptor 1 |
multiple interactions |
ISO |
Telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 mRNA]; Telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 protein] |
CTD |
PMID:22124178 |
|
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions |
EXP |
telmisartan inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA] |
CTD |
PMID:19706694 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression multiple interactions |
EXP ISO |
telmisartan results in increased expression of PPARD protein PPARD promotes the reaction [telmisartan results in increased expression of LIPE protein]; PPARD promotes the reaction [telmisartan results in increased expression of UCP1 protein]; PPARD promotes the reaction [telmisartan results in increased expression of UCP2 protein]; PPARD promotes the reaction [telmisartan results in increased expression of UCP3 protein] |
CTD |
PMID:20176998 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases activity increases expression |
ISO EXP |
PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA]]; PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; PPARG mutant form inhibits the reaction [telmisartan results in increased expression of ABCG1 mRNA]; PPARG mutant form inhibits the reaction [telmisartan results in increased expression of CD36 mRNA]; PPARG protein promotes the reaction [telmisartan inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]] Telmisartan results in increased activity of PPARG protein telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARG protein] telmisartan results in increased expression of PPARG protein telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; telmisartan promotes the reaction [Daunorubicin results in increased expression of PPARG protein] |
CTD |
PMID:18158351 PMID:20176998 PMID:20888384 PMID:21381899 PMID:22124178 PMID:24831514 PMID:28728110 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein] |
CTD |
PMID:21381899 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
ISO |
Telmisartan inhibits the reaction [Dibutyl Phthalate results in increased expression of PRKAA2 protein] |
CTD |
PMID:37356649 |
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NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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G |
Prkaca |
protein kinase cAMP-activated catalytic subunit alpha |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [Pregabalin results in decreased expression of PRKACA protein] |
CTD |
PMID:31629013 |
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NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases activity |
ISO EXP |
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [arsenite results in increased activity of PTGS2 protein]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Daunorubicin results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of PTGS2]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA] telmisartan inhibits the reaction [sodium arsenite results in increased expression of PTGS2 protein] Telmisartan results in increased activity of PTGS2 protein |
CTD |
PMID:20223228 PMID:20888384 PMID:22124178 PMID:22750630 PMID:24831514 PMID:26439596 PMID:26929000 PMID:27269004 PMID:34339004 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Pth1r |
parathyroid hormone 1 receptor |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of PTH1R protein] |
CTD |
PMID:23750309 |
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NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
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G |
Pthlh |
parathyroid hormone-like hormone |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of PTHLH protein] |
CTD |
PMID:23750309 |
|
NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP ISO |
[telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of RELA protein]; telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein] telmisartan inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] |
CTD |
PMID:20223228 PMID:22124178 PMID:24831514 PMID:26929000 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Ren |
renin |
increases expression |
EXP |
telmisartan results in increased expression of REN mRNA; telmisartan results in increased expression of REN protein |
CTD |
PMID:9533614 |
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NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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G |
Runx2 |
RUNX family transcription factor 2 |
increases expression |
EXP |
telmisartan increases expression of mRNA in mandible of rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Scn5a |
sodium voltage-gated channel alpha subunit 5 |
increases activity |
ISO |
telmisartan results in increased activity of SCN5A protein |
CTD |
PMID:29306026 |
|
NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
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G |
Sema3b |
semaphorin 3B |
multiple interactions |
ISO |
telmisartan inhibits the reaction [Calcitriol results in increased expression of SEMA3B protein]; telmisartan inhibits the reaction [Progesterone results in increased expression of SEMA3B protein] |
CTD |
PMID:21933904 |
|
NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919
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G |
Sema3f |
semaphorin 3F |
multiple interactions |
ISO |
telmisartan inhibits the reaction [Calcitriol results in increased expression of SEMA3F protein]; telmisartan inhibits the reaction [Progesterone results in increased expression of SEMA3F protein] |
CTD |
PMID:21933904 |
|
NCBI chr 8:108,357,629...108,386,569
Ensembl chr 8:108,357,629...108,387,083
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO EXP |
telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; telmisartan inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] telmisartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA] |
CTD |
PMID:17620961 PMID:19706694 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Slc18a2 |
solute carrier family 18 member A2 |
multiple interactions |
ISO |
telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC18A2 protein] |
CTD |
PMID:23747572 |
|
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
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G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
telmisartan inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
|
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein] |
CTD |
PMID:23747572 |
|
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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G |
Snca |
synuclein alpha |
multiple interactions |
ISO |
telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein] |
CTD |
PMID:23747572 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
Telmisartan inhibits the reaction [Methotrexate results in decreased expression of and results in decreased activity of SOD1 protein] |
CTD |
PMID:27269004 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
EXP |
telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Syp |
synaptophysin |
multiple interactions |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein] telmisartan inhibits the reaction [AGT protein results in decreased expression of SYP protein]; telmisartan inhibits the reaction [AGT protein results in increased ubiquitination of SYP protein] |
CTD |
PMID:18487452 |
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NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; telmisartan inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; telmisartan inhibits the reaction [Daunorubicin results in increased expression of TGFB1 protein] telmisartan results in decreased expression of TGFB1 mRNA |
CTD |
PMID:19171132 PMID:19706694 PMID:20888384 PMID:21381899 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] |
CTD |
PMID:23747572 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions affects localization decreases expression |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan affects the localization of TJP1 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 protein]; wortmannin inhibits the reaction [telmisartan affects the localization of TJP1 protein]; wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]; wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 protein] telmisartan results in decreased expression of TJP1 mRNA; telmisartan results in decreased expression of TJP1 protein |
CTD |
PMID:19252288 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
[Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 mRNA; [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 protein |
CTD |
PMID:20524934 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
multiple interactions decreases expression decreases expression |
ISO EXP |
PPARG mutant form inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; T 0070907 inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; T 0070907 inhibits the reaction [telmisartan inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] 2-chloro-5-nitrobenzanilide inhibits the reaction [Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Telmisartan inhibits the reaction [arsenite results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of TNF]; Telmisartan inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Telmisartan inhibits the reaction [sodium arsenite results in increased expression of TNF]; Telmisartan inhibits the reaction [TNF protein promotes the reaction [CEBPB protein binds to IL6 promoter]]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; telmisartan inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; telmisartan inhibits the reaction [TNF protein results in increased expression of IL6 protein] Telmisartan results in decreased expression of TNF protein telmisartan decreases expression of protein in mandible of SHR rats with periodontal disease |
CTD RGD |
PMID:19289654 PMID:20223228 PMID:21620867 PMID:21819444 PMID:22124178 PMID:22750630 PMID:24831514 PMID:26439596 PMID:26929000 PMID:29909460 PMID:34339004 PMID:33364953 More...
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RGD:329956421 |
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
increases expression |
EXP |
telmisartan increases expression of mRNA in mandible of WKY rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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G |
Tnfsf11 |
TNF superfamily member 11 |
decreases expression |
EXP |
telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
[Atorvastatin co-treated with Telmisartan] results in decreased expression of TRAF6 mRNA |
CTD |
PMID:20524934 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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G |
Ucp1 |
uncoupling protein 1 |
multiple interactions increases expression |
ISO |
PPARD promotes the reaction [telmisartan results in increased expression of UCP1 protein] |
CTD |
PMID:20176998 |
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NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
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G |
Ucp2 |
uncoupling protein 2 |
multiple interactions increases expression |
ISO |
PPARD promotes the reaction [telmisartan results in increased expression of UCP2 protein] |
CTD |
PMID:20176998 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Ucp3 |
uncoupling protein 3 |
multiple interactions increases expression |
ISO |
PPARD promotes the reaction [telmisartan results in increased expression of UCP3 protein] |
CTD |
PMID:20176998 |
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NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
telmisartan inhibits the reaction [Daunorubicin results in increased expression of VCAM1 protein] |
CTD |
PMID:20888384 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions decreases expression |
ISO EXP |
telmisartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA] telmisartan results in decreased expression of VEGFA mRNA telmisartan inhibits the reaction [sodium arsenite results in increased expression of VEGFA] |
CTD |
PMID:17724226 PMID:19171132 PMID:26439596 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vtn |
vitronectin |
decreases expression |
EXP |
telmisartan decreases expression of mRNA in mandible of SHR rats with periodontal disease |
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
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