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ONTOLOGY REPORT - ANNOTATIONS

Term:cell surface receptor signaling pathway via JAK-STAT
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Accession:GO:0007259 term browser browse the term
Definition:A cell surface receptor signaling pathway in which ligand binding causes the receptor to dimerize, bringing the receptor-associated JAKs into close proximity. The JAKs then phosphorylate and activate each other on tyrosine residues.This leads to the activation of associated STAT protein, causing the STATs to dissociate from the receptor, translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
Synonyms:exact_synonym: JAK-STAT signal transduction;   receptor signaling pathway via JAK-STAT
 narrow_synonym: JAK-STAT cascade
 xref: Wikipedia:JAK-STAT_signaling_pathway


show annotations for term's descendants           Sort by:
cell surface receptor signaling pathway via JAK-STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:11180401 RGD:1625349 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Cd40 CD40 molecule involved_in ISO
IEA 		(PMID:21410936)
GO_REF:0000107 		RGD
Ensembl		 PMID:21410936 GO_REF:0000107 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:10448081), (PMID:10500198)
(PMID:10500198) 		GO_Central
RGD		 PMID:10448081 PMID:10500198 GO_REF:0000033 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064 		JBrowse link
G Cntf ciliary neurotrophic factor involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:15342787 GO_REF:0000033, RGD:1358676 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO
IEA 		(PMID:18692472)
GO_REF:0000107 		RGD
Ensembl		 PMID:18692472 GO_REF:0000107 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha involved_in ISO (PMID:18692472) RGD PMID:18692472 NCBI chr14:113,219...118,808
Ensembl chr14:113,225...118,117 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta involved_in IEA
ISO
IBA 		GO_REF:0000107
(PMID:18692472), (PMID:9516124)
GO_REF:0000033 		Ensembl
RGD
GO_Central		 PMID:9516124 PMID:18692472 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654 		JBrowse link
G Ctf1 cardiotrophin 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395 		JBrowse link
G Ctf2 cardiotrophin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:191,764,538...191,772,881
Ensembl chr 1:191,764,538...191,772,881 		JBrowse link
G Ctr9 CTR9 component of Paf1/RNA polymerase II complex involved_in IEA
ISO 		GO_REF:0000107
(PMID:17911113) 		Ensembl
RGD		 PMID:17911113 GO_REF:0000107 NCBI chr 1:174,571,952...174,601,974
Ensembl chr 1:174,571,928...174,602,130 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10508857) 		Ensembl
RGD		 PMID:10508857 GO_REF:0000107 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO
IEA 		(PMID:11294897)
GO_REF:0000107 		RGD
Ensembl		 PMID:11294897 GO_REF:0000107 NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209 		JBrowse link
G Gh1 growth hormone 1 involved_in ISO (PMID:8063815) RGD PMID:8063815 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Ghr growth hormone receptor involved_in IDA PMID:8063815 BHF-UCL PMID:8063815 RGD:8553732 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331 		JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (PMID:20530874) RGD PMID:20530874 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 involved_in ISO (PMID:7526154), (PMID:7657660), (PMID:7813427), (PMID:8605876) RGD PMID:7526154 PMID:7657660 PMID:7813427 PMID:8605876 NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205 		JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 involved_in ISO (PMID:10556041), (PMID:7759950) RGD PMID:7759950 PMID:10556041 NCBI chr11:44,099,574...44,131,941
Ensembl chr11:44,099,753...44,131,937 		JBrowse link
G Ifnb1 interferon beta 1 acts_upstream_of
involved_in 		ISO (PMID:7813427), (PMID:8027027), (PMID:8798579), (PMID:8969169)
(PMID:10556041) 		RGD PMID:7813427 PMID:8027027 PMID:8798579 PMID:8969169 PMID:10556041 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifng interferon gamma involved_in ISO UniProtKB:Q62120 (PMID:26227742) RGD PMID:26227742 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:92,926,184...92,927,830 JBrowse link
G Ifnl3 interferon, lambda 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:92,941,988...92,943,628 JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA 		(PMID:12023369)
GO_REF:0000107 		RGD
Ensembl		 PMID:12023369 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il13 interleukin 13 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18243101) 		Ensembl
RGD		 PMID:18243101 GO_REF:0000107 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 involved_in ISO (PMID:18243101), (PMID:23103943) RGD PMID:18243101 PMID:23103943 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha IMP RGD PMID:19747902 RGD:5001122 NCBI chr17:71,712,141...71,742,072
Ensembl chr17:71,712,141...71,742,149 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IEA 		(PMID:12023369)
GO_REF:0000107 		RGD
Ensembl		 PMID:12023369 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma involved_in ISO (PMID:23103943) RGD PMID:23103943 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:70,435,343...70,439,161 		JBrowse link
G Il31ra interleukin 31 receptor A involved_in ISO
IEA 		(PMID:11877449)
GO_REF:0000107 		RGD
Ensembl		 PMID:11877449 GO_REF:0000107 NCBI chr 2:45,851,073...45,922,300
Ensembl chr 2:45,855,868...45,917,009 		JBrowse link
G Il4 interleukin 4 involved_in ISO UniProtKB:P42226 (PMID:12574355), (PMID:23103943) RGD PMID:12574355 PMID:23103943 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il4r interleukin 4 receptor involved_in ISO (PMID:18243101), (PMID:23103943) RGD PMID:18243101 PMID:23103943 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636 		JBrowse link
G Il5 interleukin 5 involved_in IEA
ISO 		GO_REF:0000107
(PMID:9516124) 		Ensembl
RGD		 PMID:9516124 GO_REF:0000107 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha involved_in IEA
ISO 		GO_REF:0000107
(PMID:9516124) 		Ensembl
RGD		 PMID:9516124 GO_REF:0000107 NCBI chr 4:141,186,749...141,221,348
Ensembl chr 4:141,171,158...141,220,943 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:28433754)
(PMID:31101051) 		RGD PMID:28433754 PMID:31101051 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISO (PMID:31101051) RGD PMID:31101051 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer acts_upstream_of_positive_effect
involved_in 		ISS
ISO
IEA 		GO_REF:0000024
(PMID:31101051)
(PMID:27384491), (PMID:8272873)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:8272873 PMID:27384491 PMID:31101051 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182 		JBrowse link
G Jak1 Janus kinase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:11294841), (PMID:28111307), (PMID:32750333), (PMID:7657660), (PMID:8232552), (PMID:8272873), (PMID:9516124) 		Ensembl
RGD		 PMID:7657660 PMID:8232552 PMID:8272873 PMID:9516124 PMID:11294841 More... GO_REF:0000107 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 involved_in
acts_upstream_of_or_within 		IDA
ISO
IBA
IEA 		(PMID:11294841), (PMID:18692472), (PMID:31145836), (PMID:9516124)
GO_REF:0000033
(PMID:10600756), (PMID:11536325)
MGI:3045147 (PMID:11821424), (PMID:12147240), (PMID:15354294), (PMID:21606371)
UniProtKB:P01580 (PMID:26227742)
GO_REF:0000117
GO_REF:0000107 		RGD
GO_Central
UniProt
Ensembl		 PMID:9516124 PMID:10600756 PMID:11294841 PMID:11536325 PMID:11821424 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:1624963 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jak3 Janus kinase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222 		JBrowse link
G Lep leptin involved_in IEA
ISO 		GO_REF:0000107
(PMID:21234744) 		Ensembl
RGD		 PMID:21234744 GO_REF:0000107 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in
acts_upstream_of_or_within 		ISO (PMID:12007403) RGD PMID:12007403 NCBI chr10:14,077,733...14,125,682
Ensembl chr10:14,078,679...14,125,681 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel acts_upstream_of_or_within
involved_in 		ISO (PMID:12007403) RGD PMID:12007403 NCBI chr14:5,541,821...5,585,140
Ensembl chr14:5,495,401...5,587,594 		JBrowse link
G Prlr prolactin receptor acts_upstream_of_or_within ISO MGI:1888377 (PMID:16469767) RGD PMID:16469767 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO (PMID:11854514) RGD PMID:11854514 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 TAS
IDA 		RGD PMID:12163036 PMID:12239110 RGD:625538, RGD:625667 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in TAS
ISO
IEA
IBA
IMP 		(PMID:11972023)
GO_REF:0000117
GO_REF:0000033
(PMID:11972023), (PMID:22002246), (PMID:28753426) 		RGD
UniProt
GO_Central		 PMID:11972023 PMID:22002246 PMID:28753426 PMID:11024034 PMID:12191995 GO_REF:0000033 GO_REF:0000117, RGD:1299057, RGD:1299060 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO
IEA 		(PMID:23139419)
GO_REF:0000107 		RGD
Ensembl		 PMID:23139419 GO_REF:0000107 NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in TAS
ISO
IEA
IBA 		(PMID:11294841), (PMID:8272873)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:8272873 PMID:11294841 PMID:8530402 GO_REF:0000033 GO_REF:0000107, RGD:730023 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000117 		GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000117 NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within
involved_in 		IDA
ISO
IBA
IEA 		(PMID:10485657)
GO_REF:0000033
GO_REF:0000117 		RGD
GO_Central
UniProt		 PMID:10485657 PMID:11064147 GO_REF:0000033 GO_REF:0000117, RGD:1624963 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within
involved_in 		IDA
ISO
IBA
IEA 		(PMID:10485657)
GO_REF:0000033
GO_REF:0000117 		RGD
GO_Central
UniProt		 PMID:10485657 PMID:11064147 GO_REF:0000033 GO_REF:0000117, RGD:1624963 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 involved_in ISO
IBA 		(PMID:12574355)
GO_REF:0000033 		RGD
GO_Central		 PMID:12574355 GO_REF:0000033 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Tnf tumor necrosis factor involved_in IDA PMID:29702085 ARUK-UCL PMID:29702085 RGD:13800534 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in IEA
ISO 		GO_REF:0000107
(PMID:21410936) 		Ensembl
RGD		 PMID:21410936 GO_REF:0000107 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO (PMID:11480573) RGD PMID:11480573 NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:7526154), (PMID:7657660), (PMID:8232552), (PMID:8605876), (PMID:9516124) RGD PMID:7526154 PMID:7657660 PMID:8232552 PMID:8605876 PMID:9516124 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:27,916,496...27,943,278 		JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Ghr growth hormone receptor IDA RGD PMID:11244571 RGD:1624962 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:8378315) RGD PMID:8378315 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,906,460...38,908,810 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20304997) 		UniProt
RGD		 PMID:20304997 GO_REF:0000024 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:82,258,243...82,427,546
Ensembl chr15:82,258,468...82,427,548 		JBrowse link
G Prl3d4 prolactin family 3, subfamily D, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:37,534,198...37,541,035
Ensembl chr17:37,534,200...37,541,061 		JBrowse link
G Prlr prolactin receptor involved_in ISO (PMID:10585417) RGD PMID:10585417 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP
ISO 		(PMID:8670418) RGD PMID:8670418 PMID:11818507 RGD:633057 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
negative regulation of peptidyl-serine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in ISO (PMID:23329839) RGD PMID:23329839 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
negative regulation of receptor signaling pathway via JAK-STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 involved_in ISO
IEA 		(PMID:23776679)
GO_REF:0000107 		RGD
Ensembl		 PMID:23776679 GO_REF:0000107 NCBI chr13:48,411,438...48,431,251
Ensembl chr13:48,411,826...48,431,255 		JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:16306601) RGD PMID:16306601 NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368 		JBrowse link
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2180364|MGI:97762 (PMID:12388746) RGD PMID:12388746 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Cish cytokine inducible SH2-containing protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986 		JBrowse link
G Dab1 DAB adaptor protein 1 acts_upstream_of_or_within ISO MGI:1857750 (PMID:18848628) RGD PMID:18848628 NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:124,369,415...124,742,584 		JBrowse link
G Gbp7 guanylate binding protein 7 involved_in ISO (PMID:33408175) RGD PMID:33408175 NCBI chr 2:233,948,774...233,970,532
Ensembl chr 2:233,948,677...233,970,526 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO
IEA 		(PMID:12444102)
GO_REF:0000107 		RGD
Ensembl		 PMID:12444102 GO_REF:0000107 NCBI chr10:106,237,988...106,256,174
Ensembl chr10:106,237,824...106,256,174 		JBrowse link
G Hmga2 high mobility group AT-hook 2 IDA RGD PMID:11390395 RGD:1601592 NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:57,765,675...57,880,341 		JBrowse link
G Leprot leptin receptor overlapping transcript involved_in ISO
IEA 		(PMID:18042720)
GO_REF:0000107 		RGD
Ensembl		 PMID:18042720 GO_REF:0000107 NCBI chr 5:121,405,170...121,417,273
Ensembl chr 5:121,404,759...121,417,275 		JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:28433754) RGD PMID:28433754 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir9-3 microRNA 9-3 involved_in ISO (PMID:25809226) RGD PMID:25809226 NCBI chr 1:142,849,400...142,849,489 JBrowse link
G Neurod1 neuronal differentiation 1 acts_upstream_of_or_within ISO (PMID:18848628) RGD PMID:18848628 NCBI chr 3:84,766,483...84,770,454
Ensembl chr 3:84,764,725...84,770,810 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in ISO
IEA 		(PMID:12444102)
GO_REF:0000107 		RGD
Ensembl		 PMID:12444102 GO_REF:0000107 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO
IEA 		UniProtKB:P05112 (PMID:12574355)
GO_REF:0000107 		RGD
Ensembl		 PMID:12574355 GO_REF:0000107 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D acts_upstream_of_or_within ISO MGI:2158795 (PMID:24843164) RGD PMID:24843164 NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903 		JBrowse link
G Sac3d1 SAC3 domain containing 1 acts_upstream_of_or_within ISO (PMID:18838617) RGD PMID:18838617 NCBI chr 1:212,843,463...212,845,842
Ensembl chr 1:212,843,463...212,845,883 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO
IEA 		(PMID:20404132)
GO_REF:0000107 		RGD
Ensembl		 PMID:20404132 GO_REF:0000107 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:40,392,633...40,414,335 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in
acts_upstream_of_or_within 		ISO
IBA
IEA 		(PMID:25019494)
MGI:2445448|MGI:2656917 (PMID:11371356), (PMID:21606371)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:11371356 PMID:21606371 PMID:25019494 GO_REF:0000033 GO_REF:0000107 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:97763 (PMID:16469767) 		GO_Central
RGD		 PMID:16469767 GO_REF:0000033 NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 involved_in ISO
IBA 		(PMID:25019494)
GO_REF:0000033 		RGD
GO_Central		 PMID:25019494 GO_REF:0000033 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Tbx1 T-box transcription factor 1 IMP RGD PMID:31982878 RGD:155882591 NCBI chr11:95,913,610...95,923,392
Ensembl chr11:95,913,610...95,923,392 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:23338840) RGD PMID:23338840 NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:148,328,079...148,334,991 		JBrowse link
negative regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2180364 (PMID:12388746) RGD PMID:12388746 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Ggnbp2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO MGI:4072637 (PMID:26764350) RGD PMID:26764350 NCBI chr10:70,208,950...70,240,554
Ensembl chr10:70,208,950...70,246,260 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300) RGD PMID:27796300 NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:82,258,243...82,427,546
Ensembl chr15:82,258,468...82,427,548 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:12359225) 		UniProt
RGD		 PMID:12359225 GO_REF:0000024 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO (PMID:9202127) RGD PMID:9202127 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
positive regulation of peptidyl-serine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:22483866) RGD PMID:22483866 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:16280321) RGD PMID:16280321 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ret ret proto-oncogene acts_upstream_of_or_within ISO (PMID:23872421) RGD PMID:23872421 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556 		JBrowse link
positive regulation of receptor signaling pathway via JAK-STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 IMP RGD PMID:18394428 RGD:2317907 NCBI chr13:48,411,438...48,431,251
Ensembl chr13:48,411,826...48,431,255 		JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 acts_upstream_of_or_within ISO MGI:4439325 (PMID:20075866) RGD PMID:20075866 NCBI chr 7:64,782,618...64,799,624
Ensembl chr 7:64,782,612...64,799,640 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 IMP RGD PMID:15746188 RGD:1626095 NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315 		JBrowse link
G Calm1 calmodulin 1 involved_in ISO (PMID:11972023), (PMID:35568036) RGD PMID:11972023 PMID:35568036 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381 		JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:11972023), (PMID:35568036) RGD PMID:11972023 PMID:35568036 NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657 		JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:11972023), (PMID:35568036) RGD PMID:11972023 PMID:35568036 NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:11972023), (PMID:35568036)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:11972023 PMID:35568036 GO_REF:0000024 GO_REF:0000107 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504 		JBrowse link
G Cntf ciliary neurotrophic factor IDA RGD PMID:15574731 RGD:1626128 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488 		JBrowse link
G Cpap centrosome assembly and centriole elongation protein acts_upstream_of_or_within ISO (PMID:12198240) RGD PMID:12198240 NCBI chr15:34,742,838...34,806,020
Ensembl chr15:34,742,838...34,802,421 		JBrowse link
G Crlf3 cytokine receptor-like factor 3 involved_in ISO (PMID:19427400) RGD PMID:19427400 NCBI chr10:65,521,296...65,559,162
Ensembl chr10:65,521,492...65,558,804 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IDA RGD PMID:21114767 RGD:5135266 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000024
(PMID:23568032) 		Ensembl
UniProt
RGD		 PMID:23568032 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Ep300 EP300 lysine acetyltransferase involved_in ISO (PMID:16257975) RGD PMID:16257975 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:15534001)
GO_REF:0000107
(PMID:16837552) 		UniProt
RGD
Ensembl		 PMID:15534001 PMID:16837552 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579 		JBrowse link
G Gh1 growth hormone 1 involved_in ISO
IBA 		(PMID:8923468)
GO_REF:0000033 		RGD
GO_Central		 PMID:8923468 GO_REF:0000033 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Ghr growth hormone receptor involved_in IDA
IMP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:11064147 PMID:10976913 GO_REF:0000033, RGD:1624963, RGD:1624964 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15156153) 		UniProt
Ensembl
RGD		 PMID:15156153 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISS
ISO 		GO_REF:0000024
(PMID:15156153) 		UniProt
RGD		 PMID:15156153 GO_REF:0000024 NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021 		JBrowse link
G Ifne interferon, epsilon involved_in ISO (PMID:23964570) RGD PMID:23964570 NCBI chr 5:108,687,443...108,688,103
Ensembl chr 5:108,687,443...108,688,103 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:12483210) RGD PMID:12483210 NCBI chr 1:92,926,184...92,927,830 JBrowse link
G Il10 interleukin 10 involved_in ISO
IBA
IEA 		(PMID:16982608)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:16982608 GO_REF:0000033 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha involved_in ISO
IEA 		(PMID:16982608)
GO_REF:0000107 		RGD
Ensembl		 PMID:16982608 GO_REF:0000107 NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:54,459,882...54,475,028 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta involved_in ISO
IEA 		(PMID:16982608)
GO_REF:0000107 		RGD
Ensembl		 PMID:16982608 GO_REF:0000107 NCBI chr11:44,132,471...44,154,062
Ensembl chr11:44,132,189...44,154,053 		JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:7638186) RGD PMID:7638186 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:12023369), (PMID:7638186) RGD PMID:7638186 PMID:12023369 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:12023369), (PMID:7638186) RGD PMID:7638186 PMID:12023369 NCBI chr16:18,654,207...18,668,887
Ensembl chr16:18,654,207...18,666,824 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 involved_in ISO (PMID:7638186) RGD PMID:7638186 NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:12023369) RGD PMID:12023369 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il23r interleukin 23 receptor involved_in ISO (PMID:12023369) RGD PMID:12023369 NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:97,909,972...98,004,110 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 involved_in IMP
IEA
ISO 		GO_REF:0000107
(PMID:7888666) 		Ensembl
RGD		 PMID:7888666 PMID:10867506 GO_REF:0000107, RGD:2303751 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il6 interleukin 6 involved_in IDA
IMP
ISO 		STAT3 phosphorylation
(PMID:12419823), (PMID:17324931) 		RGD PMID:12419823 PMID:17324931 PMID:16413512 PMID:19061939 PMID:15659221 RGD:1580483, RGD:2306937, RGD:1641883 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il7r interleukin 7 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO
IBA
IEA 		(PMID:21135090)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:21135090 GO_REF:0000033 GO_REF:0000107 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Lep leptin involved_in IMP
ISS
ISO
IBA
IEA 		GO_REF:0000024
(PMID:17344214)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000117
(PMID:16825198) 		UniProt
RGD
GO_Central
Ensembl		 PMID:16825198 PMID:17344214 PMID:21250909 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:5128518 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:25019494) RGD PMID:25019494 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:6,023,182...6,023,290 		JBrowse link
G Notch1 notch receptor 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15156153) 		UniProt
Ensembl
RGD		 PMID:15156153 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613 		JBrowse link
G Prl prolactin involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:12552091)
GO_REF:0000107
MGI:102709 (PMID:12388746)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:12388746 PMID:12552091 GO_REF:0000033 GO_REF:0000107 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Prl2a1 prolactin family 2, subfamily A, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,139,406...37,145,498
Ensembl chr17:37,139,407...37,145,498 		JBrowse link
G Prl2b1 prolactin family 2, subfamily B, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,799,545...37,806,572
Ensembl chr17:37,799,583...37,806,572 		JBrowse link
G Prl2c1 prolactin family 2, subfamily C, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,089,507...37,097,827
Ensembl chr17:37,089,507...37,097,827 		JBrowse link
G Prl3b1 prolactin family 3, subfamily B, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,952,063...37,957,722
Ensembl chr17:37,952,066...37,957,722 		JBrowse link
G Prl3c1 prolactin family 3, subfamily C, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,993,057...37,998,828
Ensembl chr17:37,993,048...37,998,781 		JBrowse link
G Prl3d1l1 prolactin family 3, subfamily D, member 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:38,041,402...38,047,329
Ensembl chr17:38,041,345...38,047,331 		JBrowse link
G Prl3d4 prolactin family 3, subfamily D, member 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,534,198...37,541,035
Ensembl chr17:37,534,200...37,541,061 		JBrowse link
G Prl4a1 prolactin family 4, subfamily A, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:36,949,416...36,957,358
Ensembl chr17:36,949,447...36,957,393 		JBrowse link
G Prl5a1 prolactin family 5, subfamily A, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:36,794,163...36,801,601
Ensembl chr17:36,794,157...36,801,601 		JBrowse link
G Prl5a2 prolactin family 5, subfamily A, member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:36,661,123...36,667,465
Ensembl chr17:36,661,129...36,667,465 		JBrowse link
G Prl6a1 prolactin family 6, subfamily A, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,883,623...37,888,467
Ensembl chr17:37,883,627...37,891,059 		JBrowse link
G Prl7a1l-ps1 prolactin family 7, subfamily a, member 1 like, pseudogene involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,380,733...37,393,602
Ensembl chr17:37,379,789...37,392,991 		JBrowse link
G Prl7a3 prolactin family 7, subfamily A, member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,294,564...37,307,439
Ensembl chr17:37,294,499...37,307,439 		JBrowse link
G Prl7b1 prolactin family 7, subfamily B, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,410,605...37,423,139
Ensembl chr17:37,414,947...37,423,126 		JBrowse link
G Prl7c1 prolactin family 7, subfamily c, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,183,189...37,190,649
Ensembl chr17:37,183,189...37,190,618 		JBrowse link
G Prl7d1 prolactin family 7, subfamily D, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,191,153...37,261,734
Ensembl chr17:37,255,240...37,262,097 		JBrowse link
G Prl8a2 prolactin family 8, subfamily A, member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,821,651...37,830,676
Ensembl chr17:37,821,651...37,830,676 		JBrowse link
G Prl8a4 prolactin family 8, subfamily A, member 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,638,351...37,644,439
Ensembl chr17:37,638,351...37,644,439 		JBrowse link
G Prl8a5 prolactin family 8, subfamily A, member 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,674,027...37,680,240
Ensembl chr17:37,674,027...37,680,240 		JBrowse link
G Prl8a7 prolactin family 8, subfamily A, member 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,767,210...37,773,112
Ensembl chr17:37,767,271...37,773,106 		JBrowse link
G Prl8a9 prolactin family 8, subfamily A, member 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:37,503,450...37,509,258
Ensembl chr17:37,503,450...37,509,255 		JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 acts_upstream_of_or_within ISO MGI:5490784 (PMID:23839944) RGD PMID:23839944 NCBI chr 8:67,444,757...67,464,719
Ensembl chr 8:67,444,742...67,464,720 		JBrowse link
G Tlr2 toll-like receptor 2 IDA RGD PMID:19661221 RGD:597538516 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Usp1 ubiquitin specific peptidase 1 involved_in ISO
IEA 		(PMID:37289831)
GO_REF:0000107 		RGD
Ensembl		 PMID:37289831 GO_REF:0000107 NCBI chr 5:118,703,056...118,714,426
Ensembl chr 5:118,702,868...118,714,434 		JBrowse link
G Wdr48 WD repeat domain 48 involved_in ISO
IEA 		(PMID:37289831)
GO_REF:0000107 		RGD
Ensembl		 PMID:37289831 GO_REF:0000107 NCBI chr 8:128,499,721...128,532,930
Ensembl chr 8:128,499,716...128,532,930 		JBrowse link
positive regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl2bp ARF like GTPase 2 binding protein involved_in ISS
ISO 		GO_REF:0000024
(PMID:18234692) 		UniProt
RGD		 PMID:18234692 GO_REF:0000024 NCBI chr19:10,342,895...10,352,529
Ensembl chr19:10,342,895...10,352,514 		JBrowse link
G Cntf ciliary neurotrophic factor involved_in
acts_upstream_of_or_within 		ISO (PMID:21912637)
(PMID:15207851) 		RGD PMID:15207851 PMID:21912637 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISS
ISO 		GO_REF:0000024
(PMID:8007983) 		UniProt
RGD		 PMID:8007983 GO_REF:0000024 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806 		JBrowse link
G Ctf1 cardiotrophin 1 involved_in ISO (PMID:21912637) RGD PMID:21912637 NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISS
ISO 		GO_REF:0000024
(PMID:16837552) 		UniProt
RGD		 PMID:16837552 GO_REF:0000024 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (PMID:17561467) RGD PMID:17561467 NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:23438599) RGD PMID:23438599 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:15156153) 		UniProt
RGD		 PMID:15156153 GO_REF:0000024 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (PMID:18641331) RGD PMID:18641331 NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:16280321) RGD PMID:16280321 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:15166220) RGD PMID:15166220 NCBI chr 1:92,926,184...92,927,830 JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:12372421) RGD PMID:12372421 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il13 interleukin 13 involved_in ISO (PMID:18243101) RGD PMID:18243101 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 involved_in ISO (PMID:18243101) RGD PMID:18243101 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:10903731) RGD PMID:10903731 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:10485657) RGD PMID:10485657 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:17673207) RGD PMID:17673207 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il31ra interleukin 31 receptor A involved_in ISO (PMID:11877449) RGD PMID:11877449 NCBI chr 2:45,851,073...45,922,300
Ensembl chr 2:45,855,868...45,917,009 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10485657) RGD PMID:10485657 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il4r interleukin 4 receptor involved_in ISO (PMID:18243101) RGD PMID:18243101 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636 		JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO (PMID:15659653) RGD PMID:15659653 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:15156153) 		UniProt
RGD		 PMID:15156153 GO_REF:0000024 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:21135090) RGD PMID:21135090 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:11254359) RGD PMID:11254359 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267 		JBrowse link
G Osm oncostatin M involved_in ISO (PMID:21912637) RGD PMID:21912637 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300) RGD PMID:27796300 NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO (PMID:27796300) RGD PMID:27796300 NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:11254359) RGD PMID:11254359 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:82,258,243...82,427,546
Ensembl chr15:82,258,468...82,427,548 		JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 involved_in ISO UniProtKB:Q9UNG2 (PMID:23892569) RGD PMID:23892569 NCBI chr 5:171,901,734...171,904,578
Ensembl chr 5:171,901,717...171,904,576 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO UniProtKB:Q9Y5U5 (PMID:23892569) RGD PMID:23892569 NCBI chr13:76,366,790...76,440,673
Ensembl chr13:76,366,771...76,376,608 		JBrowse link
regulation of receptor signaling pathway via JAK-STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dot1l DOT1 like histone lysine methyltransferase involved_in ISO
IEA 		(PMID:22002246)
GO_REF:0000107 		RGD
Ensembl		 PMID:22002246 GO_REF:0000107 NCBI chr 7:9,569,439...9,607,095
Ensembl chr 7:9,569,439...9,607,095 		JBrowse link
G Egf epidermal growth factor involved_in ISS
ISO 		GO_REF:0000024
(PMID:15156153) 		UniProt
RGD		 PMID:15156153 GO_REF:0000024 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 acts_upstream_of_or_within ISO (PMID:10954736) RGD PMID:10954736 NCBI chr18:16,160,686...16,196,307
Ensembl chr18:16,160,671...16,196,414 		JBrowse link
G Ephb2 Eph receptor B2 IDA RGD PMID:33722292 RGD:127285641 NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:154,179,065...154,360,615 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:15156153)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:15156153 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205 		JBrowse link
G Il9 interleukin 9 acts_upstream_of_or_within ISO (PMID:18551134) RGD PMID:18551134 NCBI chr17:8,117,028...8,120,151
Ensembl chr17:8,117,028...8,120,151 		JBrowse link
G Mst1 macrophage stimulating 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:2445230 (PMID:25049204) 		GO_Central
RGD		 PMID:25049204 GO_REF:0000033 NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:117,647,438...117,652,015 		JBrowse link
G Pigu phosphatidylinositol glycan anchor biosynthesis, class U involved_in IEA
ISO 		GO_REF:0000107
(PMID:15034568) 		Ensembl
RGD		 PMID:15034568 GO_REF:0000107 NCBI chr 3:164,245,011...164,341,444
Ensembl chr 3:164,245,011...164,341,912 		JBrowse link
G Prl prolactin acts_upstream_of_or_within ISO (PMID:12147240) RGD PMID:12147240 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO (PMID:27050391) RGD PMID:27050391 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO MGI:2656917 (PMID:21606371) RGD PMID:21606371 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:23386060) RGD PMID:23386060 NCBI chr16:58,478,882...58,498,046
Ensembl chr16:58,478,900...58,498,046 		JBrowse link
G Gusb glucuronidase, beta acts_upstream_of_or_within ISO (PMID:19375967) RGD PMID:19375967 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G Il22 interleukin 22 acts_upstream_of_or_within ISO (PMID:12700595) RGD PMID:12700595 NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:55,686,896...55,692,201 		JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 acts_upstream_of_or_within ISO (PMID:12700595) RGD PMID:12700595 NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO MGI:2656917 (PMID:21606371) RGD PMID:21606371 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
serine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5 cyclin-dependent kinase 5 acts_upstream_of_or_within ISO (PMID:15096606) RGD PMID:15096606 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 acts_upstream_of_or_within ISO (PMID:15096606) RGD PMID:15096606 NCBI chr10:65,981,692...65,985,831
Ensembl chr10:65,978,911...65,989,272 		JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C acts_upstream_of_or_within ISO (PMID:37226685) RGD PMID:37226685 NCBI chr 4:51,805,686...51,853,030
Ensembl chr 4:51,805,703...51,853,030 		JBrowse link
G Il24 interleukin 24 IDA RGD PMID:19258414 RGD:5147427 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Mir301a microRNA 301a acts_upstream_of_or_within ISO (PMID:22517757) RGD PMID:22517757 NCBI chr10:72,422,599...72,422,698
Ensembl chr10:72,422,599...72,422,698 		JBrowse link
tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fer FER tyrosine kinase involved_in ISO (PMID:19147545) RGD PMID:19147545 NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:110,967,390...111,274,315 		JBrowse link
G Il15 interleukin 15 involved_in ISO (PMID:12244150) RGD PMID:12244150 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il21 interleukin 21 involved_in ISO (PMID:12244150) RGD PMID:12244150 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Jak1 Janus kinase 1 acts_upstream_of_or_within ISO MGI:2176165|MGI:5688302 (PMID:27671227) RGD PMID:27671227 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within IMP
ISO 		(PMID:11821424), (PMID:12388746) RGD PMID:11821424 PMID:12388746 PMID:15659221 PMID:17920330 RGD:1641883, RGD:5686906 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Lif LIF, interleukin 6 family cytokine acts_upstream_of_or_within ISO (PMID:15012602) RGD PMID:15012602 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053 		JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (PMID:15012602) RGD PMID:15012602 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827 		JBrowse link
G Ptk6 protein tyrosine kinase 6 involved_in ISO (PMID:16568091), (PMID:17997837) RGD PMID:16568091 PMID:17997837 NCBI chr 3:188,684,633...188,693,224
Ensembl chr 3:188,684,633...188,693,224 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19688
    cellular process 18845
      signal transduction 7248
        cell surface receptor signaling pathway 2949
          cell surface receptor signaling pathway via STAT 198
            cell surface receptor signaling pathway via JAK-STAT 173
              negative regulation of receptor signaling pathway via JAK-STAT + 26
              positive regulation of receptor signaling pathway via JAK-STAT + 70
              regulation of receptor signaling pathway via JAK-STAT + 112
              tyrosine phosphorylation of STAT protein + 44
Path 2
Term Annotations click to browse term
  biological_process 19688
    biological regulation 13561
      regulation of biological process 13114
        signaling 7810
          signal transduction 7248
            cell surface receptor signaling pathway 2949
              cell surface receptor signaling pathway via STAT 198
                cell surface receptor signaling pathway via JAK-STAT 173
                  negative regulation of receptor signaling pathway via JAK-STAT + 26
                  positive regulation of receptor signaling pathway via JAK-STAT + 70
                  regulation of receptor signaling pathway via JAK-STAT + 112
                  tyrosine phosphorylation of STAT protein + 44
paths to the root