Tbx1 (T-box transcription factor 1)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Tbx1 (T-box transcription factor 1) Rattus norvegicus

Analyze

Symbol:

Tbx1

Name:

T-box transcription factor 1

RGD ID:

1307734

Description:

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including animal organ development; positive regulation of cell population proliferation; and vasculature development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in DiGeorge syndrome; tetralogy of Fallot; and velocardiofacial syndrome. Orthologous to human TBX1 (T-box transcription factor 1); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; C60 fullerene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC360737; T-box 1; T-box transcription factor TBX1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TBX1 (T-box transcription factor 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tbx1 (T-box 1)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Tbx1 (T-box transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TBX1 (T-box transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TBX1 (T-box transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tbx1 (T-box transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TBX1 (T-box transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	TBX1 (T-box transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tbx1 (T-box transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TBX10 (T-box transcription factor 10)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	TBX1 (T-box transcription factor 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Tbx1 (T-box 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	tbx1 (T-box 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	tbx-8	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER)
Caenorhabditis elegans (roundworm):	tbx-9	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER)
Drosophila melanogaster (fruit fly):	org-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	82,409,275 - 82,419,058 (+)	NCBI
Rnor_6.0 Ensembl	11	86,552,022 - 86,560,969 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	11	86,552,022 - 86,561,647 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	11	89,651,955 - 89,661,553 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	84,400,980 - 84,410,631 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	11	84,445,104 - 84,451,228 (+)	NCBI
Celera	11	81,184,983 - 81,193,848 (+)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO,ISS)

autistic disorder (ISO)

congenital heart disease (ISO)

Conotruncal Cardiac Defects (ISO)

Craniofacial Abnormalities (ISO)

DiGeorge syndrome (ISO)

dilated cardiomyopathy (ISO)

double outlet right ventricle (ISS)

epilepsy (ISO)

genetic disease (ISO)

hemorrhagic disease (ISO)

hypoplastic left heart syndrome (ISO)

intellectual disability (ISO)

KBG syndrome (ISO)

Neurodevelopmental Disorders (ISO)

otitis media (ISS)

polycystic ovary syndrome (ISO)

primary immunodeficiency disease (ISO)

schizophrenia (ISO)

Takao VCF Syndrome (ISO)

tetralogy of Fallot (ISO)

velocardiofacial syndrome (ISO)

Venous Thrombosis (ISO)

visual epilepsy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

C60 fullerene (EXP)

carbon nanotube (ISO)

CHIR 99021 (ISO)

chloroprene (ISO)

choline (ISO)

copper atom (ISO)

copper(0) (ISO)

dexamethasone (ISO)

dichloroacetic acid (ISO)

folic acid (ISO)

furan (EXP)

hydrogen peroxide (ISO)

L-methionine (ISO)

Licarin A (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

resveratrol (ISO)

SB 431542 (ISO)

selenomethionine (ISO)

silicon dioxide (ISO)

sulforaphane (ISO)

testosterone enanthate (ISO)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vanadyl sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (ISO,ISS)

anterior/posterior pattern specification (ISO,ISS)

aorta morphogenesis (ISO,ISS)

artery morphogenesis (ISO,ISS)

biological_process (ND)

blood vessel development (ISO,ISS)

blood vessel morphogenesis (ISO,ISS)

blood vessel remodeling (ISO)

cell fate specification (IBA,ISO,ISS)

cell population proliferation (ISO,ISS)

cellular response to fibroblast growth factor stimulus (ISO,ISS)

cellular response to retinoic acid (ISO,ISS)

cochlea morphogenesis (ISO,ISS)

coronary artery morphogenesis (ISO,ISS)

determination of left/right symmetry (ISO,ISS)

ear morphogenesis (ISO,ISS)

embryonic cranial skeleton morphogenesis (ISO,ISS)

embryonic viscerocranium morphogenesis (ISO,ISS)

enamel mineralization (ISO,ISS)

epithelial cell differentiation (ISO,ISS)

face morphogenesis (ISO,ISS)

hard palate development (ISO)

heart development (ISO,ISS)

heart morphogenesis (ISO,ISS)

inner ear morphogenesis (ISO,ISS)

lymph vessel development (ISO,ISS)

mesenchymal cell apoptotic process (ISO,ISS)

mesoderm development (ISO,ISS)

middle ear morphogenesis (ISO,ISS)

muscle cell fate commitment (ISO,ISS)

muscle organ development (ISO,ISS)

muscle organ morphogenesis (ISO,ISS)

muscle tissue morphogenesis (ISO,ISS)

negative regulation of cell differentiation (ISO,ISS)

negative regulation of mesenchymal cell apoptotic process (ISO,ISS)

negative regulation of transcription by RNA polymerase II (ISO)

neural crest cell migration (ISO,ISS)

odontogenesis of dentin-containing tooth (ISO,ISS)

otic vesicle morphogenesis (ISO)

outer ear morphogenesis (ISO,ISS)

outflow tract morphogenesis (ISO,ISS)

outflow tract septum morphogenesis (ISO,ISS)

parathyroid gland development (ISO,ISS)

pattern specification process (ISO,ISS)

pharyngeal system development (ISO,ISS)

positive regulation of cell population proliferation (ISO,ISS)

positive regulation of epithelial cell proliferation (ISO,ISS)

positive regulation of MAPK cascade (ISO,ISS)

positive regulation of mesenchymal cell proliferation (ISO,ISS)

positive regulation of protein phosphorylation (ISO,ISS)

positive regulation of secondary heart field cardioblast proliferation (ISO)

positive regulation of tongue muscle cell differentiation (ISO,ISS)

positive regulation of transcription by RNA polymerase II (ISO,ISS)

positive regulation of transcription, DNA-templated (ISO,ISS)

regulation of animal organ morphogenesis (ISO,ISS)

regulation of transcription by RNA polymerase II (IBA,ISO,ISS)

retinoic acid receptor signaling pathway (ISO,ISS)

semicircular canal morphogenesis (ISO,ISS)

sensory perception of sound (ISO,ISS)

social behavior (ISO,ISS)

soft palate development (ISO,ISS)

thymus development (ISO,ISS)

thyroid gland development (ISO,ISS)

tongue morphogenesis (ISO,ISS)

vagus nerve morphogenesis (ISO,ISS)

Cellular Component

cellular_component (ND)

nucleus (ISO,ISS)

Molecular Function

DNA binding (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

molecular_function (ND)

protein binding (ISO)

protein homodimerization activity (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding (ISO)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	Hu T, etal., Development. 2004 Nov;131(21):5491-502. Epub 2004 Oct 6.
4.	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline
6.	RGD automated data pipeline
7.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	RGD automated import pipeline for gene-chemical interactions
9.	RGD comprehensive gene curation
10.	Stoller JZ and Epstein JA, Hum Mol Genet. 2005 Apr 1;14(7):885-92. Epub 2005 Feb 9.
11.	Xu H, etal., Development. 2005 Oct;132(19):4387-95. Epub 2005 Sep 1.

Additional References at PubMed

PMID:11111039	PMID:11239417	PMID:11242049	PMID:11242110	PMID:11971873	PMID:12913075	PMID:14585638	PMID:15064766	PMID:15084464	PMID:15175244	PMID:15190012	PMID:15385444
PMID:15652707	PMID:15843409	PMID:16284121	PMID:16399080	PMID:16556915	PMID:16600992	PMID:16684884	PMID:16696966	PMID:16914493	PMID:17000704	PMID:17074316	PMID:17164259
PMID:17273972	PMID:17825816	PMID:17916582	PMID:18231833	PMID:18583714	PMID:18816853	PMID:18816858	PMID:19233155	PMID:19389367	PMID:19531352	PMID:19700621	PMID:19745164
PMID:19855134	PMID:20122914	PMID:20439995	PMID:20463296	PMID:20501333	PMID:20807544	PMID:20816801	PMID:20939858	PMID:21177346	PMID:21364285	PMID:24817956	PMID:24821700
PMID:27422448	PMID:31982878

Genomics

Comparative Map Data

Tbx1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	82,409,275 - 82,419,058 (+)	NCBI
Rnor_6.0 Ensembl	11	86,552,022 - 86,560,969 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	11	86,552,022 - 86,561,647 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	11	89,651,955 - 89,661,553 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	84,400,980 - 84,410,631 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	11	84,445,104 - 84,451,228 (+)	NCBI
Celera	11	81,184,983 - 81,193,848 (+)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

TBX1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	22	19,756,703 - 19,783,593 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	22	19,756,703 - 19,783,593 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	22	19,744,226 - 19,771,116 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	18,124,226 - 18,151,116 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	22	18,118,779 - 18,129,409	NCBI
Celera	22	3,596,280 - 3,623,183 (+)	NCBI
Cytogenetic Map	22	q11.21	NCBI
HuRef	22	3,364,192 - 3,390,621 (+)	NCBI		HuRef
CHM1_1	22	19,744,073 - 19,770,823 (+)	NCBI		CHM1_1

Tbx1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	18,399,729 - 18,409,421 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	16	18,399,729 - 18,409,421 (-)	Ensembl
GRCm38	16	18,580,979 - 18,590,671 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	18,580,979 - 18,590,671 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	18,581,806 - 18,587,062 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	16	18,495,276 - 18,500,532 (-)	NCBI			mm8
Celera	16	19,155,983 - 19,161,240 (-)	NCBI		Celera
Cytogenetic Map	16	A3	NCBI
cM Map	16	11.51	NCBI

Tbx1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	18,319,762 - 18,325,337 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	18,320,674 - 18,327,062 (-)	NCBI	ChiLan1.0	ChiLan1.0

TBX1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	22	18,192,954 - 18,213,786 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	22	2,521,080 - 2,541,267 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

TBX1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	29,529,071 - 29,533,240 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	29,528,878 - 29,532,784 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	29,486,387 - 29,494,624 (-)	NCBI
ROS_Cfam_1.0	26	30,932,031 - 30,939,925 (-)	NCBI
UMICH_Zoey_3.1	26	28,979,960 - 28,987,853 (-)	NCBI
UNSW_CanFamBas_1.0	26	28,605,398 - 28,613,298 (-)	NCBI
UU_Cfam_GSD_1.0	26	29,690,874 - 29,698,814 (-)	NCBI

Tbx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	139,083,586 - 139,092,022 (-)	NCBI
SpeTri2.0	NW_004936619	3,662,567 - 3,670,470 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TBX1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	51,289,143 - 51,296,725 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	51,289,376 - 51,297,110 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TBX1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	5,980,114 - 5,986,313 (-)	NCBI
ChlSab1.1 Ensembl	19	5,980,587 - 5,987,244 (-)	Ensembl

Tbx1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	386,763 - 395,515 (+)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	19016272	90463843	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	28314665	86994795	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	30435339	86714631	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	43090338	86714631	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	46583209	86714631	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	47264023	86994547	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	47264023	86994547	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	57858810	90463843	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	59943023	90463843	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	60109842	87141948	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	62653365	86714475	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	62653365	86714483	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	64494671	90463843	Rat
1354593	Stl12	Serum triglyceride level QTL 12	3.36		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	11	69649708	90463843	Rat
1354656	Bvd3	Brain ventricular dilatation QTL 3	3.64	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	72720029	86994795	Rat
10450831	Scl80	Serum cholesterol level QTL 80	4.7	0.01	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	11	80358408	87200449	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	46
Count of miRNA genes:	45
Interacting mature miRNAs:	46
Transcripts:	ENSRNOT00000002597
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium								3			8
Low	3	14	6	4	2	4	8	8	10	12	29	11	8
Below cutoff		29	21	9	10	9			43	21	4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000002597 ⟹ ENSRNOP00000002597

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	11	86,552,022 - 86,560,969 (+)	Ensembl

RefSeq Acc Id:

NM_001108322 ⟹ NP_001101792

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	82,409,275 - 82,418,380 (+)	NCBI
Rnor_6.0	11	86,552,022 - 86,560,969 (+)	NCBI
Rnor_5.0	11	89,651,955 - 89,661,553 (+)	NCBI
RGSC_v3.4	11	84,400,980 - 84,410,631 (+)	RGD
Celera	11	81,184,983 - 81,193,848 (+)	RGD

Sequence:

show sequence

CCGGCAGGGGGAGCGAGGCAGAAGGGAGAGACGGCCGGTGCAGCCGAGGCCTCGGAGGGCACCG
CCCACCGGGGCCCCAGGCCCTCGGACCGGGCGAAACTTCGCCGGCTACCAGGATCCCCAGCCGG
GATGCACTTCAGTACAGTCACCAGGGACATGGAAGCCTTCGCGGCCAGCAGTCTGAGCGGCCTG
GGAGCCCCGTCGCCTGGCGCCGACCCGTTCGGCCCTCGGGAGCCGCCGCCACCGCGCTACGACC
CGTGCACCGCTGCCCCCGGTGCCCCGGGCCCGCCGCCTCCGCCGCGCGCCTACCCTTTCGCGCC
CGCCCCCGGGGCGGCTAGCAGCTCGGCGGCGGAGTCCGAGGGTCCTGGGGCTAGCCGCGCGGCC
GCGGCCAAGGCGCCGGTGAAGAAGAACCCAAAGGTGGCCAGCGTGAGCGTGCAGCTGGAAATGA
AGGCGCTATGGGACGAGTTCAATCAGCTGGGCACCGAGATGATCGTCACCAAGGCAGGCAGACG
AATGTTCCCCACCTTCCAAGTGAAGCTTTTTGGAATGGACCCGATGGCTGACTACATGCTCCTC
ATGGACTTTGTGCCTGTGGATGACAAGCGCTACCGGTACGCTTTCCACAGCTCCTCCTGGCTGG
TGGCTGGCAAGGCAGATCCTGCCACCCCTGGCCGAGTGCACTACCACCCGGACTCGCCCGCGAA
GGGCGCGCAGTGGATGAAGCAGATCGTATCTTTCGACAAGCTGAAGCTCACCAATAACCTGCTG
GACGACAATGGCCACATTATTCTTAACTCCATGCACAGATACCAGCCCCGTTTCCATGTTGTTT
ATGTGGACCCTCGAAAAGACAGCGAGAAATACGCAGAGGAGAACTTCAAAACTTTTGTGTTTGA
GGAGACACGCTTCACTGCAGTCACCGCCTACCAGAATCACCGGATCACGCAGCTTAAGATTGCC
AGCAACCCCTTCGCCAAAGGCTTCCGGGACTGCGACCCGGAGGACTGGCCCCGAAACCACCGGC
CCGGAGCGCTGCCGCTTGTAAGTGCCTTTGCTCGCTCTCGGAATCCCGTGGCTTCCCCCACGCA
GCCCAACGGAGCGGACAAAGATGTGGCAGAAGCCCGGCGCGAGTTCGACCGTGACTCTGGACCC
GCAGCGCTCGGCGACGCCACGCACCCGCCGCAGCTGCTGGCGCGCGTGCTGAGCCCCGCACTGC
CTGGGCCTGGTGGCCTCGTCCCGCTACCTGGCGGATCCGGAGGCCGCCACAGTCCCCCGCACGC
TGATCTGCGCCTGGAGGCTCCGGGCGCATCCGAACCGCTGCACCACCATCCCTACAAGTACCCG
GCGGCCGCCTACGACCACTACCTCGGGGCCAAGAGCCGGCCGGCGCCCTACCCGCTGCCAGGCC
TGCGCGGCCACGGCTACCACCCACATGCGCACCCGCACGCGCACCCGCACCACCACCACCACCC
GGCGGTGAACCCGGCCGCCGCCGCCGCCGCAGCAGCAGCAGCCAACGTGTACTCCTCGGCGGCC
GCGCCGCCCGGTGCCTACGACTACTGCCCCAGATAGTGCGCCCGCGCGCGGGCCCCAAGGGCCA
CCCAAGGACGTGTTCCCCATCTGGGGAGCCATGCGGGCCTCCCGCCCGCCAGTGCCAAAGCTCT
CGTCCGAGGCGGAAGGAAATGGTATTTATTGTTCTCCGCGAGACCGCGTCGCCTCCGGCCCGGC
CGGCAATAGCAGTGTAGACGACCCGAGTGAGCCCCGCCTGCGGGCGGTGTAGATACATGTAGAT
ATCTTGTAGATACTGTAGATACTGCACCGGCGCCGATTTCATAAACGGTTTCGCCTCTTTTGG

hide sequence

RefSeq Acc Id:

XM_006248619 ⟹ XP_006248681

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	82,411,796 - 82,419,058 (+)	NCBI
Rnor_6.0	11	86,553,787 - 86,561,647 (+)	NCBI
Rnor_5.0	11	89,651,955 - 89,661,553 (+)	NCBI

Sequence:

show sequence

CACCCTCCGGATGTAAAAGCGTCCTGGCCAGAGGCGGGCGGTGCGCGCGGGGTGCGCGTGACGC
TGGGGCTCCCGGTCTTGTGCGGCCTGGGCGGCGTCCCACGGCTCGCTTCCCCACCACGAAAGCA
AGCTGACCCAAGGGGCCTGTAGGGGCAATTGTTGGTGAGGTCCAGCTCTGCGGCACGGAGGGAC
GGAGGACTCCGCAGCCCTGGGGCTATCTGCCTGTGGCTTTTGCGAGAGCCGGAGCCGCTCTCTT
ACCCAGGTGCAGGGGCCGCTGGGGAGGAGGTGGAGGCAGGTGGGGCCAAGGGCAGGGCTAGACT
CAGGCAGCCCCTCAGTGCCTCGTCAGTGCCCTGCCATCTCAGACTGGGACTGAGTGCTCGAGAC
ATAGAAACTTCTCCTTTGGGGCTGTAGACTCTGGTGGTGGCTTCGCCGAATAGAGGGGACGCCC
AACCTCTGCAGAAGCTGCAGGATGTTCAAGGGGCGTTGGTCACACAGGGCCCCGGGAGGAGAGA
CCAGGGACAGAGAGCTTGCAAGGCAGGAGGGCCCTGAATTTCCAGGGCGCTCCAACTGTTCGGA
CTCCCGGGCCAATATTGGCTGAAAATGGGGGGGTCTCATGACGCCATAATCCCTTGAGCCCTGG
ACCGGCGGCTGTGAGTGGCACCACAGGCCCCCGCCCCCGGGCCCCCTGCGCTGGGCTGGGCGCG
GTGCGGCAGGGCGTACGCAGTCGGAGGCGGCGCCGGTCAGGCCCGGGCGCCTATGGACGCGCGG
AGCCCGCTGTCTGCCCGGGCCAGCGCATTCAGCATCGCCTCTCTTGTTGCAGCCGAGGCCTCGG
AGGGCACCGCCCACCGGGGCCCCAGGCCCTCGGACCGGGCGAAACTTCGCCGGCTACCAGGATC
CCCAGCCGGGATGCACTTCAGTACAGTCACCAGGGACATGGAAGCCTTCGCGGCCAGCAGTCTG
AGCGGCCTGGGAGCCCCGTCGCCTGGCGCCGACCCGTTCGGCCCTCGGGAGCCGCCGCCACCGC
GCTACGACCCGTGCACCGCTGCCCCCGGTGCCCCGGGCCCGCCGCCTCCGCCGCGCGCCTACCC
TTTCGCGCCCGCCCCCGGGGCGGCTAGCAGCTCGGCGGCGGAGTCCGAGGGTCCTGGGGCTAGC
CGCGCGGCCGCGGCCAAGGCGCCGGTGAAGAAGAACCCAAAGGTGGCCAGCGTGAGCGTGCAGC
TGGAAATGAAGGCGCTATGGGACGAGTTCAATCAGCTGGGCACCGAGATGATCGTCACCAAGGC
AGGCAGACGAATGTTCCCCACCTTCCAAGTGAAGCTTTTTGGAATGGACCCGATGGCTGACTAC
ATGCTCCTCATGGACTTTGTGCCTGTGGATGACAAGCGCTACCGGTACGCTTTCCACAGCTCCT
CCTGGCTGGTGGCTGGCAAGGCAGATCCTGCCACCCCTGGCCGAGTGCACTACCACCCGGACTC
GCCCGCGAAGGGCGCGCAGTGGATGAAGCAGATCGTATCTTTCGACAAGCTGAAGCTCACCAAT
AACCTGCTGGACGACAATGGCCACATTATTCTTAACTCCATGCACAGATACCAGCCCCGTTTCC
ATGTTGTTTATGTGGACCCTCGAAAAGACAGCGAGAAATACGCAGAGGAGAACTTCAAAACTTT
TGTGTTTGAGGAGACACGCTTCACTGCAGTCACCGCCTACCAGAATCACCGGATCACGCAGCTT
AAGATTGCCAGCAACCCCTTCGCCAAAGGCTTCCGGGACTGCGACCCGGAGGACTGGCCCCGAA
ACCACCGGCCCGGAGCGCTGCCGCTTGTAAGTGCCTTTGCTCGCTCTCGGAATCCCGTGGCTTC
CCCCACGCAGCCCAACGGAGCGGACAAAGATGTGGCAGAAGCCCGGCGCGAGTTCGACCGTGAC
TCTGGACCCGCAGCGCTCGGCGACGCCACGCACCCGCCGCAGCTGCTGGCGCGCGTGCTGAGCC
CCGCACTGCCTGGGCCTGGTGGCCTCGTCCCGCTACCTGGCGGATCCGGAGGCCGCCACAGTCC
CCCGCACGCTGATCTGCGCCTGGAGGCTCCGGGCGCATCCGAACCGCTGCACCACCATCCCTAC
AAGTACCCGGCGGCCGCCTACGACCACTACCTCGGGGCCAAGAGCCGGCCGGCGCCCTACCCGC
TGCCAGGCCTGCGCGGCCACGGCTACCACCCACATGCGCACCCGCACGCGCACCCGCACCACCA
CCACCACCCGGCGGTGAACCCGGCCGCCGCCGCCGCCGCAGCAGCAGCAGCCAACGTGTACTCC
TCGGCGGCCGCGCCGCCCGGTGCCTACGACTACTGCCCCAGATAGTGCGCCCGCGCGCGGGCCC
CAAGGGCCACCCAAGGACGTGTTCCCCATCTGGGGAGCCATGCGGGCCTCCCGCCCGCCAGTGC
CAAAGCTCTCGTCCGAGGCGGAAGGAAATGGTATTTATTGTTCTCCGCGAGACCGCGTCGCCTC
CGGCCCGGCCGGCAATAGCAGTGTAGACGACCCGAGTGAGCCCCGCCTGCGGGCGGTGTAGATA
CATGTAGATATCTTGTAGATACTGTAGATACTGCACCGGCGCCGATTTCATAAACGGTTTCGCC
TCTTTTGGAAACTGCCGGTGTGGCTATTCTTTTGCATCTAATTCGATTGGGCTGGGCGTCTTTG
GGGCAGAGGGCTTAGTCTTCTCAGCCCTGGTCACCGGTGTGAGCGTGGAGCAAGGGTCTCCCTC
CCTTCTCTCCCCTGGGGCTCACTGCCTCCCTTCCGCAGCTCCTCCGGTCCACTACAGGCTGGGC
GCGCGGTTTACCCAGGGCAGACACCTGCAGCTGGTGGGGCAGGATTTGGGCCTGAACGCTGGCC
TGTTTACAGGACTAGACCATAAGTTTTTCCGTGAAAGCCGGGAATGATATTCGGGACAGGACAC
TGTCCATCCGGCCTCGGATGGCATGCGGAAAGCAGTGGGCTCGACTCTTCCAGCGTTGCCCTGG
CCTGGCACCAGCCCAGAATTGTGTTTCCCCCTGTTTATTGACTTTATTCCCTGAATGTCCCCAC
AGAGTGATGGGGAGCGGGGGTCGCACAATGACAGTGGTCATGAGTCATCTTGAAACTCCCGGTG
AAGCAATTTTTCCCAGGCCAGGTGGCTGGGTGACCTGTCTCCATTAACTCAACACTATCATAGT
GGCCAAAGGAACCCTTTGATCCCTCCCTTCCTGCGCCCCAGCAGGAAGGGCCAACCGAAGGCCA
GCCAGAGTTAAGGCTGGCTTATGCCTCAAATAAATGGGAAATGTCA

hide sequence

RefSeq Acc Id:

XM_017598029 ⟹ XP_017453518

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	86,553,787 - 86,560,969 (+)	NCBI

Sequence:

show sequence

CACCCTCCGGATGTAAAAGCGTCCTGGCCAGAGGCGGGCGGTGCGCGCGGGGTGCGCGTGACGC
TGGGGCTCCCGGTCTTGTGCGGCCTGGGCGGCGTCCCACGGCTCGCTTCCCCACCACGAAAGCA
AGCTGACCCAAGGGGCCTGTAGGGGCAATTGTTGGTGAGGTCCAGCTCTGCGGCACGGAGGGAC
GGAGGACTCCGCAGCCCTGGGGCTATCTGCCTGTGGCTTTTGCGAGAGCCGGAGCCGCTCTCTT
ACCCAGCCGAGGCCTCGGAGGGCACCGCCCACCGGGGCCCCAGGCCCTCGGACCGGGCGAAACT
TCGCCGGCTACCAGGATCCCCAGCCGGGATGCACTTCAGTACAGTCACCAGGGACATGGAAGCC
TTCGCGGCCAGCAGTCTGAGCGGCCTGGGAGCCCCGTCGCCTGGCGCCGACCCGTTCGGCCCTC
GGGAGCCGCCGCCACCGCGCTACGACCCGTGCACCGCTGCCCCCGGTGCCCCGGGCCCGCCGCC
TCCGCCGCGCGCCTACCCTTTCGCGCCCGCCCCCGGGGCGGCTAGCAGCTCGGCGGCGGAGTCC
GAGGGTCCTGGGGCTAGCCGCGCGGCCGCGGCCAAGGCGCCGGTGAAGAAGAACCCAAAGGTGG
CCAGCGTGAGCGTGCAGCTGGAAATGAAGGCGCTATGGGACGAGTTCAATCAGCTGGGCACCGA
GATGATCGTCACCAAGGCAGGCAGACGAATGTTCCCCACCTTCCAAGTGAAGCTTTTTGGAATG
GACCCGATGGCTGACTACATGCTCCTCATGGACTTTGTGCCTGTGGATGACAAGCGCTACCGGT
ACGCTTTCCACAGCTCCTCCTGGCTGGTGGCTGGCAAGGCAGATCCTGCCACCCCTGGCCGAGT
GCACTACCACCCGGACTCGCCCGCGAAGGGCGCGCAGTGGATGAAGCAGATCGTATCTTTCGAC
AAGCTGAAGCTCACCAATAACCTGCTGGACGACAATGGCCACATTATTCTTAACTCCATGCACA
GATACCAGCCCCGTTTCCATGTTGTTTATGTGGACCCTCGAAAAGACAGCGAGAAATACGCAGA
GGAGAACTTCAAAACTTTTGTGTTTGAGGAGACACGCTTCACTGCAGTCACCGCCTACCAGAAT
CACCGGATCACGCAGCTTAAGATTGCCAGCAACCCCTTCGCCAAAGGCTTCCGGGACTGCGACC
CGGAGGACTGGCCCCGAAACCACCGGCCCGGAGCGCTGCCGCTTGTAAGTGCCTTTGCTCGCTC
TCGGAATCCCGTGGCTTCCCCCACGCAGCCCAACGGAGCGGACAAAGATGTGGCAGAAGCCCGG
CGCGAGTTCGACCGTGACTCTGGACCCGCAGCGCTCGGCGACGCCACGCACCCGCCGCAGCTGC
TGGCGCGCGTGCTGAGCCCCGCACTGCCTGGGCCTGGTGGCCTCGTCCCGCTACCTGGCGGATC
CGGAGGCCGCCACAGTCCCCCGCACGCTGATCTGCGCCTGGAGGCTCCGGGCGCATCCGAACCG
CTGCACCACCATCCCTACAAGTACCCGGCGGCCGCCTACGACCACTACCTCGGGGCCAAGAGCC
GGCCGGCGCCCTACCCGCTGCCAGGCCTGCGCGGCCACGGCTACCACCCACATGCGCACCCGCA
CGCGCACCCGCACCACCACCACCACCCGGCGGTGAACCCGGCCGCCGCCGCCGCCGCAGCAGCA
GCAGCCAACGTGTACTCCTCGGCGGCCGCGCCGCCCGGTGCCTACGACTACTGCCCCAGATAGT
GCGCCCGCGCGCGGGCCCCAAGGGCCACCCAAGGACGTGTTCCCCATCTGGGGAGCCATGCGGG
CCTCCCGCCCGCCAGTGCCAAAGCTCTCGTCCGAGGCGGAAGGAAATGGTATTTATTGTTCTCC
GCGAGACCGCGTCGCCTCCGGCCCGGCCGGCAATAGCAGTGTAGACGACCCGAGTGAGCCCCGC
CTGCGGGCGGTGTAGATACATGTAGATATCTTGTAGATACTGTAGATACTGCACCGGCGCCGAT
TTCATAAACGGTTTCGCCTCTTTTGG

hide sequence

RefSeq Acc Id:

XM_039088501 ⟹ XP_038944429

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	82,413,248 - 82,418,097 (+)	NCBI

RefSeq Acc Id:

XR_005491042

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	82,410,829 - 82,417,321 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101792	(Get FASTA)	NCBI Sequence Viewer
	XP_006248681	(Get FASTA)	NCBI Sequence Viewer
	XP_038944429	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL77947	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001101792 ⟸ NM_001108322

- UniProtKB:

D4A2E9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MHFSTVTRDMEAFAASSLSGLGAPSPGADPFGPREPPPPRYDPCTAAPGAPGPPPPPRAYPFAP
APGAASSSAAESEGPGASRAAAAKAPVKKNPKVASVSVQLEMKALWDEFNQLGTEMIVTKAGRR
MFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAK
GAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFE
ETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLVSAFARSRNPVASPTQ
PNGADKDVAEARREFDRDSGPAALGDATHPPQLLARVLSPALPGPGGLVPLPGGSGGRHSPPHA
DLRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHAHPHHHHHP
AVNPAAAAAAAAAANVYSSAAAPPGAYDYCPR

hide sequence

RefSeq Acc Id:

XP_006248681 ⟸ XM_006248619

- Peptide Label:

isoform X1

- Sequence:

show sequence

MDARSPLSARASAFSIASLVAAEASEGTAHRGPRPSDRAKLRRLPGSPAGMHFSTVTRDMEAFA
ASSLSGLGAPSPGADPFGPREPPPPRYDPCTAAPGAPGPPPPPRAYPFAPAPGAASSSAAESEG
PGASRAAAAKAPVKKNPKVASVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDP
MADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKL
KLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
ITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLVSAFARSRNPVASPTQPNGADKDVAEARRE
FDRDSGPAALGDATHPPQLLARVLSPALPGPGGLVPLPGGSGGRHSPPHADLRLEAPGASEPLH
HHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHAHPHHHHHPAVNPAAAAAAAAAA
NVYSSAAAPPGAYDYCPR

hide sequence

RefSeq Acc Id:

XP_017453518 ⟸ XM_017598029

- Peptide Label:

isoform X2

- Sequence:

show sequence

MHFSTVTRDMEAFAASSLSGLGAPSPGADPFGPREPPPPRYDPCTAAPGAPGPPPPPRAYPFAP
APGAASSSAAESEGPGASRAAAAKAPVKKNPKVASVSVQLEMKALWDEFNQLGTEMIVTKAGRR
MFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAK
GAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFE
ETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLVSAFARSRNPVASPTQ
PNGADKDVAEARREFDRDSGPAALGDATHPPQLLARVLSPALPGPGGLVPLPGGSGGRHSPPHA
DLRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHAHPHHHHHP
AVNPAAAAAAAAAANVYSSAAAPPGAYDYCPR

hide sequence

RefSeq Acc Id:

ENSRNOP00000002597 ⟸ ENSRNOT00000002597

RefSeq Acc Id:	XP_038944429 ⟸ XM_039088501
- Peptide Label:	isoform X2

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307734	AgrOrtholog
Ensembl Genes	ENSRNOG00000001892	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000002597	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002597	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.820	UniProtKB/TrEMBL
InterPro	p53-like_TF_DNA-bd	UniProtKB/TrEMBL
	T-box_sf	UniProtKB/TrEMBL
	TF_T-box	UniProtKB/TrEMBL
	TF_T-box_CS	UniProtKB/TrEMBL
KEGG Report	rno:360737	UniProtKB/TrEMBL
NCBI Gene	360737	ENTREZGENE
PANTHER	TF_T-box	UniProtKB/TrEMBL
Pfam	T-box	UniProtKB/TrEMBL
PhenoGen	Tbx1	PhenoGen
PRINTS	TBOX	UniProtKB/TrEMBL
PROSITE	TBOX_1	UniProtKB/TrEMBL
	TBOX_2	UniProtKB/TrEMBL
	TBOX_3	UniProtKB/TrEMBL
SMART	TBOX	UniProtKB/TrEMBL
Superfamily-SCOP	P53_like_DNA_bnd	UniProtKB/TrEMBL
UniProt	D4A2E9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-05	Tbx1	T-box transcription factor 1	Tbx1	T-box 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Tbx1	T-box 1	Tbx1_predicted	T-box 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Tbx1_predicted	T-box 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM