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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Diabetes Complications
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Accession:DOID:9002661 term browser browse the term
Definition:Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
Synonyms:exact_synonym: Complications of Diabetes Mellitus;   Diabetes Complication;   Diabetes Mellitus Complication;   Diabetes Mellitus Complications;   Diabetes Related Complications;   Diabetes-Related Complication;   Diabetic Complication;   Diabetic Complications
 primary_id: MESH:D048909;   RDO:0001421


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Diabetes Complications term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr13:76,193,929...76,476,119
Ensembl chr13:95,349,915...95,582,058 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25304492 PMID:25541468 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: therapeutic CTD PMID:23500772 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:20479236 RGD:7241550 NCBI chr14:76,885,923...76,894,456 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:20479236 RGD:7241550 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253 		JBrowse link
G CASP9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24252320 RGD:13782355 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO RGD PMID:15963101 RGD:2307154 NCBI chr10:91,547,865...91,598,918
Ensembl chr10:95,022,482...95,105,653 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO Associated with obesity RGD PMID:21282363 RGD:6906933 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO protein: decreased expression: serum RGD PMID:18025762 RGD:7242563 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G GLO1 glyoxalase I no_association ISO DNA:SNP: :419C>A (human) RGD PMID:21738003 RGD:7242569 NCBI chr 6:38,247,881...38,275,098
Ensembl chr 6:39,434,746...39,461,971 		JBrowse link
G HDAC4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35554780 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G MUC1 mucin 1, cell surface associated ISO associated with Diabetes Mellitus, Experimental RGD PMID:23977093 RGD:7349380 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 1:26,174,055...26,176,689
Ensembl chr 1:27,230,362...27,232,942 		JBrowse link
G PLN phospholamban ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:diaphragm RGD PMID:23443767 RGD:7327179 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668 		JBrowse link
G PON1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19003935 NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21548839 RGD:6484542 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505 		JBrowse link
G SLC10A2 solute carrier family 10 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr13:84,200,209...84,224,164
Ensembl chr13:103,336,073...103,359,359 		JBrowse link
G SLC51A solute carrier family 51 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 3:193,554,592...193,573,984
Ensembl chr 3:203,504,092...203,521,354 		JBrowse link
G SLC51B SLC51 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr15:43,988,512...43,992,939
Ensembl chr15:62,268,738...62,277,160 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18057998 RGD:6771339 NCBI chr 1:26,359,818...26,418,910
Ensembl chr 1:27,414,937...27,475,089 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
background diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase ISO associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum: RGD PMID:24092995 RGD:9068931 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO protein:decreased expression:aqueous humor: RGD PMID:23853629 RGD:10402120 NCBI chr13:9,584,850...9,779,542 JBrowse link
G LOC100979269 alpha-2-macroglobulin treatment ISO RGD PMID:10848441 RGD:10046010 NCBI chr12:9,154,457...9,202,833
Ensembl chr12:9,385,359...9,433,979 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 ISO protein:increased activity:serum: RGD PMID:28724746 RGD:151356966 NCBI chr10:30,579,220...30,607,249
Ensembl chr10:30,933,483...30,960,824 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein:decreased expression:vitreous: RGD PMID:19799585 RGD:10449447 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883 		JBrowse link
chromosome 17q11.2 deletion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF135 ring finger protein 135 ISO ClinVar Annotator: match by term: Chromosome 17q11.2 deletion syndrome, 1.4Mb | ClinVar Annotator: match by term: Macrocephaly, macrosomia, facial dysmorphism syndrome ClinVar PMID:17632510 PMID:21681106 PMID:25741868 PMID:27535533 PMID:28135719 More... NCBI chr17:25,843,447...25,869,874 JBrowse link
Cleft Palate, Proliferative Retinopathy, and Developmental Delay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRC32 leucine rich repeat containing 32 ISO ClinVar Annotator: match by term: Cleft palate, proliferative retinopathy, and developmental delay OMIM
ClinVar		 PMID:25741868 PMID:30976112 NCBI chr11:71,708,222...71,721,426
Ensembl chr11:75,354,997...75,367,440 		JBrowse link
diabetic angiopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO ClinVar Annotator: match by term: Microvascular complications of diabetes, susceptibility to, 3 ClinVar PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G ADCY3 adenylate cyclase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr2A:24,812,729...24,913,539
Ensembl chr2A:24,908,108...25,009,163 		JBrowse link
G ADCY8 adenylate cyclase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20372816 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19733855 NCBI chr 4:50,773,244...50,790,474
Ensembl chr 4:56,605,322...56,622,418 		JBrowse link
G ASS1 argininosuccinate synthase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25033204 NCBI chr 9:101,569,442...101,625,899
Ensembl chr 9:130,219,993...130,276,036 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:15878326 RGD:7241570 NCBI chr14:76,885,923...76,894,456 JBrowse link
G CASP3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23154660 RGD:11526153 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384 		JBrowse link
G CD28 CD28 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased expression:T cell RGD PMID:15504310 RGD:2307197 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213 		JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:serum RGD PMID:14963650 RGD:2314223 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202 		JBrowse link
G CREM cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr10:35,247,426...35,335,545
Ensembl chr10:35,825,218...35,912,432 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 susceptibility ISO associated with Diabetic Foot;DNA:polymorphism:3' utr (human) RGD PMID:16723689 RGD:2306558 NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231 		JBrowse link
G EPO erythropoietin ISO ClinVar Annotator: match by term: Microvascular complications of diabetes, susceptibility to, 2 OMIM
ClinVar		 PMID:18458324 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974 		JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
protein:increased expression:plasma		 RGD PMID:9285207 PMID:16371118 RGD:2313861 RGD:2313868 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G FAS Fas cell surface death receptor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15803113 RGD:2315753 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
G FASLG Fas ligand ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15803113 PMID:25381014 RGD:2315753 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281 		JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:12716757 RGD:1601179 NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003 		JBrowse link
G GCH1 GTP cyclohydrolase 1 ISO associated with type 2 diabetes mellitus;DNA:SNV: :C59038T (human) RGD PMID:19515581 RGD:329961327 NCBI chr14:35,428,676...35,489,359
Ensembl chr14:53,706,723...53,767,393 		JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha ISO RGD PMID:21411989 RGD:7242686 NCBI chr17:4,980,083...4,983,219 JBrowse link
G GPX1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G GSR glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics; protein:reduced_activity:blood RGD PMID:16338763 RGD:1600708 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557 		JBrowse link
G HFE homeostatic iron regulator ISO ClinVar Annotator: match by term: MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 7 | ClinVar Annotator: match by term: Microvascular complications of diabetes, susceptibility to, 7 ClinVar PMID:678784 PMID:8696333 PMID:8896549 PMID:8896550 PMID:8931958 More... NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16959961 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:aorta		 RGD PMID:18093596 PMID:18796303 RGD:2306988 RGD:2313473 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr 7:46,538,566...46,545,536
Ensembl chr 7:46,658,097...46,662,584 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO ClinVar Annotator: match by term: Microvascular complications of diabetes, susceptibility to, 4 OMIM
ClinVar		 PMID:25741868 PMID:28492532 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
G ITGAM integrin subunit alpha M ISO protein:increased expression:neutrophil (human) RGD PMID:18496641 RGD:329901826 NCBI chr16:23,634,476...23,707,147
Ensembl chr16:31,630,146...31,702,406 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO RGD PMID:12477149 RGD:1582581 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16681562 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea RGD PMID:19241604 PMID:19587355 RGD:2313210 RGD:4891384 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea		 CTD
RGD		 PMID:12124201 PMID:19241604 PMID:29329611 RGD:13504708 RGD:4891384 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased tyrosine phosphorylation:conceptus RGD PMID:10329590 RGD:2311657 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067 		JBrowse link
G PLAT plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:18945481 RGD:2311663 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G PON1 paraoxonase 1 ISO ClinVar Annotator: match by term: RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO ClinVar PMID:9011577 PMID:9661650 PMID:11335891 PMID:11788650 PMID:11889198 More... NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21926342 RGD:10041069 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G RBP4 retinol binding protein 4 disease_progression ISO protein:increased expression:blood serum (human) RGD PMID:33294897 RGD:329853310 NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868 		JBrowse link
G SERPINE1 serpin family E member 1 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:deletion, haplotype:promoter:g.-676_-674delG (human) RGD PMID:9844142 RGD:8547700 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
G SERPINF1 serpin family F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568 		JBrowse link
G SOD1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr21:18,029,831...18,037,526 JBrowse link
G SOD2 superoxide dismutase 2 ISO ClinVar Annotator: match by term: SUPEROXIDE DISMUTASE 2 POLYMORPHISM OMIM
ClinVar		 PMID:8633092 PMID:10425186 PMID:12624725 PMID:15591282 PMID:16538174 More... NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:mesentery, blood vessel RGD PMID:10625572 RGD:2300063 NCBI chr 5:147,087,903...147,112,466
Ensembl chr 5:153,090,181...153,115,750 		JBrowse link
G THBS1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
G THBS2 thrombospondin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 6:167,290,482...167,329,319
Ensembl chr 6:172,130,727...172,169,028 		JBrowse link
G TNF tumor necrosis factor susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:c.-308G>A (human) RGD PMID:18575614 RGD:2313255 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO ClinVar Annotator: match by term: Microvascular complications of diabetes, susceptibility to, 1 OMIM
ClinVar		 PMID:11978667 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
Diabetic Cardiomyopathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
G ADIPOR1 adiponectin receptor 1 ISO associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chr 1:178,542,496...178,560,055
Ensembl chr 1:182,837,589...182,854,782 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:heart (rat) RGD PMID:23251674 RGD:7244283 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29353218 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15587404 PMID:16025228 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G APOA1 apolipoprotein A1 ISO CTD Direct Evidence: therapeutic CTD PMID:18332268 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G ATF6 activating transcription factor 6 ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr 1:137,178,629...137,382,256
Ensembl chr 1:140,977,750...141,176,725 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16685413 PMID:21441944 RGD:6771209 NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923 		JBrowse link
G ATP7A ATPase copper transporting alpha treatment ISO RGD PMID:24927960 RGD:11341676 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21296063 RGD:10053697 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:myocardium (mouse) RGD PMID:21296063 PMID:21474815 RGD:10053697 RGD:11522727 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468 		JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:28992627 RGD:13782299 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G CASQ2 calsequestrin 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21441944 RGD:6771209 NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311 		JBrowse link
G CASR calcium sensing receptor ISO protein:decreased expression:myocardium (rat) RGD PMID:22137362 RGD:7205677 NCBI chr 3:119,278,071...119,383,901
Ensembl chr 3:126,252,765...126,285,268 		JBrowse link
G CFL1 cofilin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:27576917 RGD:11568692 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806 		JBrowse link
G CTNNB1 catenin beta 1 ISO mRNA,protein:increased expression:heart RGD PMID:25586361 RGD:13524855 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23453443 PMID:23853776 RGD:10412713 RGD:9586347 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr12:101,506,845...101,524,407
Ensembl chr12:104,901,997...104,919,329 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458 		JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:11375343 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:36462176 NCBI chr 6:157,852,565...157,990,049
Ensembl chr 6:162,878,661...162,997,762 		JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23843977 RGD:7247697 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371 		JBrowse link
G INS insulin ISO CTD Direct Evidence: therapeutic CTD PMID:20828608 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G KLK1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16129698 NCBI chr19:47,784,368...47,789,004
Ensembl chr19:56,677,579...56,682,216 		JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:35235096 NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768 		JBrowse link
G LOC100979269 alpha-2-macroglobulin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21742475 RGD:10046044 NCBI chr12:9,154,457...9,202,833
Ensembl chr12:9,385,359...9,433,979 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO associated with type 2 diabetes mellitus;protein:decreased expression:myocardium of ventricle (rat) RGD PMID:22146585 RGD:155883162 NCBI chr 6:88,398,329...88,470,926
Ensembl chr 6:91,664,263...91,737,468 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MTOR mechanistic target of rapamycin kinase ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841 		JBrowse link
G MYLK2 myosin light chain kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:9005973 RGD:1580244 NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment
ameliorates		 ISO associated with Diabetes Mellitus, Experimental RGD PMID:23353773 PMID:23453443 PMID:36044268 RGD:10412713 RGD:10412721 RGD:156430337 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:29274332 RGD:13504685 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233 		JBrowse link
G NOTCH1 notch receptor 1 treatment ISO RGD PMID:32828943 RGD:405650202 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G NPPA natriuretic peptide A treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23497378 RGD:7297056 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G NRG1 neuregulin 1 treatment ISO associated with Diabetes Mellitus, Experimental;protein:decreased expresssion:left ventricle myocardium RGD PMID:22285193 PMID:32828943 RGD:10449013 RGD:405650202 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ameliorates ISO RGD PMID:36044268 RGD:156430337 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977 		JBrowse link
G PLN phospholamban ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:heart left ventricle RGD PMID:22185592 RGD:7327207 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO Strain: ZDF RGD PMID:19317897 RGD:5509944 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G RYR2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16685413 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509 		JBrowse link
G SLC25A4 solute carrier family 25 member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:18945756 NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 treatment ISO RGD PMID:27058979 RGD:13628396 NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16980342 NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935 		JBrowse link
G TERT telomerase reverse transcriptase treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21264070 RGD:11038677 Ensembl chr 5:1,300,960...1,338,872 JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17909696 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23843977 RGD:7247697 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455 		JBrowse link
diabetic cataract term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSR glutathione-disulfide reductase ISO RGD PMID:12518238 RGD:10401829 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557 		JBrowse link
Diabetic Cystopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nuclei: RGD PMID:20879002 RGD:10053565 NCBI chr  X:119,256,425...119,292,612
Ensembl chr  X:129,550,287...129,586,271 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23129268 RGD:10053664 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
Diabetic Embryopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain ISO RGD PMID:26419589 RGD:13792560 NCBI chr11:65,300,889...65,305,020 JBrowse link
diabetic encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23529380 PMID:24291733 RGD:7244255 RGD:8553040 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G APP amyloid beta precursor protein treatment ISO associated with type 2 diabetes mellitus RGD PMID:28885995 RGD:13782056 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17601561 RGD:7771546 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26970304 RGD:13792771 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771 		JBrowse link
G IDE insulin degrading enzyme ISO associated with type 2 diabetes mellitus RGD PMID:27306699 RGD:13792796 NCBI chr10:89,196,295...89,320,223
Ensembl chr10:92,716,540...92,833,353 		JBrowse link
G NGF nerve growth factor treatment ISO associated with Diabetes Mellitus, Experimental
associated with Experimental Diabetes Mellitus		 RGD PMID:23528019 PMID:32681844 RGD:402463968 RGD:7242845 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NGFR nerve growth factor receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24291733 RGD:8553040 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060 		JBrowse link
Diabetic Foot term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:plasma RGD PMID:20836881 RGD:5686889 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO associated with Diabetes Mellitus, Type 2;protein:decreased expression:blood RGD PMID:21941211 RGD:6767555 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G CRP C-reactive protein disease_progression ISO protein:increased expression:blood: RGD PMID:22712631 RGD:6906887 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G GJA1 gap junction protein alpha 1 ISO protein:increased expression:dermis RGD PMID:22455314 RGD:7207269 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO mRNA,protein:decreased expression:blood serum, foot (human) RGD PMID:34293021 RGD:155260332 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B severity ISO DNA:polymorphism: :1538G>A (human) RGD PMID:19731315 RGD:8662463 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:decreased expression:fibroblast of dermis,stratum basale of epidermis: RGD PMID:10727985 RGD:8549356 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IL15 interleukin 15 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:dermis, endothelial cell RGD PMID:17014667 RGD:2313575 NCBI chr 4:133,693,995...134,115,470
Ensembl chr 4:145,402,111...145,416,622 		JBrowse link
G ITGAM integrin subunit alpha M ISO protein:increased expression:pes (human) RGD PMID:37087778 RGD:329853756 NCBI chr16:23,634,476...23,707,147
Ensembl chr16:31,630,146...31,702,406 		JBrowse link
G MBL2 mannose binding lectin 2 ISO protein:increased expression:serum: RGD PMID:19997692 RGD:8694068 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432 		JBrowse link
G MMP9 matrix metallopeptidase 9 severity ISO RGD PMID:22688339 RGD:8547813 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129 		JBrowse link
G NOTCH1 notch receptor 1 ISO protein:increased expression:skin, epidermis: RGD PMID:30886104 RGD:155646129 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G PLAT plasminogen activator, tissue type ISO RGD PMID:17275886 RGD:2311669 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G PTX3 pentraxin 3 ISO protein:decreased expression:plasma (human) RGD PMID:30767386 RGD:38501100 NCBI chr 3:154,485,470...154,492,293
Ensembl chr 3:162,537,577...162,543,652 		JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO DNA:SNPs,haplotype: :rs4986790,rs4986791,rs10759931,rs1927911(human); RGD PMID:23936790 RGD:7777174 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
diabetic ketoacidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP2 aquaporin 2 ISO RGD PMID:12021537 RGD:2314345 NCBI chr12:38,796,300...38,804,559
Ensembl chr12:39,690,289...39,698,397 		JBrowse link
G INS insulin ISO CTD Direct Evidence: therapeutic CTD PMID:11430560 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G INSR insulin receptor ISO RGD PMID:15254588 RGD:1302526 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889 		JBrowse link
G PAX4 paired box 4 ISO ClinVar Annotator: match by term: Diabetes mellitus, ketosis-prone | ClinVar Annotator: match by term: Diabetes mellitus, ketosis-prone, susceptibility to ClinVar
OMIM		 PMID:9536098 PMID:15509590 PMID:17576681 PMID:18414213 PMID:25741868 More... NCBI chr 7:119,605,924...119,613,579
Ensembl chr 7:132,260,859...132,268,516 		JBrowse link
G SERPINA7 serpin family A member 7 ISO protein:decreased expression:serum RGD PMID:6768790 RGD:2312332 NCBI chr  X:95,163,842...95,169,230
Ensembl chr  X:105,541,475...105,548,132 		JBrowse link
Diabetic Nephropathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment
no_association
susceptibility		 ISO associated with Diabetes Mellitus, Type 1;DNA:insertion/deletion
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Diabetes Mellitus, Type 2;DNA:insertion/deletion		 RGD
CTD		 PMID:7729604 PMID:7909524 PMID:8314010 PMID:10099885 PMID:10857950 More... RGD:11039044 RGD:2311449 RGD:7829777 RGD:7829780 RGD:8548872 RGD:8548885 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G ACE2 angiotensin converting enzyme 2 no_association ISO associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:decreased expression:kidney
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple (human)
mRNA, protein:altered expression:kidney		 RGD
CTD		 PMID:12623933 PMID:17600118 PMID:18235039 PMID:19034303 PMID:19077419 More... RGD:2313796 RGD:2313797 RGD:2313800 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G ACTN1 actinin alpha 1 ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr14:49,460,390...49,565,986
Ensembl chr14:68,335,694...68,440,836 		JBrowse link
G ACVR1 activin A receptor type 1 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:11675415 RGD:2313802 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing no_association
disease_progression		 ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs1501299 (human)
protein:increased expression:plasma
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs2241766 (human)		 RGD
CTD		 PMID:17942768 PMID:17970779 PMID:21945031 PMID:23260797 RGD:5686409 RGD:8694443 RGD:8694475 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
G ADORA1 adenosine A1 receptor ISO associated with Diabetes Mellitus, Experimental RGD PMID:19552053 RGD:2313803 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism (human) RGD PMID:15660746 RGD:2313545 NCBI chr2A:103,198,432...103,202,506
Ensembl chr2A:97,040,126...97,041,472 		JBrowse link
G ADRB3 adrenoceptor beta 3 ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:9867224 RGD:5684403 NCBI chr 8:37,263,730...37,267,475
Ensembl chr 8:34,441,311...34,443,949 		JBrowse link
G AGER advanced glycosylation end-product specific receptor susceptibility
treatment		 ISO associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1704G>T (human)
associated with Diabetes Mellitus;DNA:polymorphisms, haplotype:cds, intron:p.G82S, g.2184A>G (rs2070600, rs3134940) (human)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney cortex, glomerulus		 RGD PMID:12651605 PMID:14747204 PMID:19142024 PMID:21533139 PMID:21856399 More... RGD:2325651 RGD:7243248 RGD:7243852 RGD:7244174 RGD:7244187 RGD:8695982 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G AGT angiotensinogen no_association
disease_progression		 ISO CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :p.M235T (human)
associated with Diabetes Mellitus, Type 1;DNA:polymorphism: :p.M235T (human)		 CTD
RGD		 PMID:8772723 PMID:10862638 PMID:11938025 PMID:17890855 PMID:19014923 More... RGD:11039058 RGD:8548868 RGD:8548872 RGD:8548885 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1166A>C (human)
associated with Diabetes Mellitus, Experimental		 RGD PMID:12172324 PMID:12476891 RGD:6903861 RGD:8548891 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:18565281 RGD:6903847 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
G AHSG alpha 2-HS glycoprotein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15698447 RGD:2313813 NCBI chr 3:183,644,223...183,652,620
Ensembl chr 3:192,110,770...192,119,915 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B susceptibility ISO associated with Diabetes Mellitus, Type 1;DNA:promoter:repeat:g.?(AC)n (human) RGD PMID:9000706 PMID:9215310 RGD:734542 RGD:8548641 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095 		JBrowse link
G ALB albumin ISO associated with Metabolic Syndrome X;protein:increased expression:urine
CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Experimental;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine		 RGD
CTD		 PMID:16380483 PMID:19246226 PMID:19397971 PMID:19424163 PMID:21441310 RGD:2306882 RGD:2306885 RGD:2306886 RGD:5135032 NCBI chr 4:50,773,244...50,790,474
Ensembl chr 4:56,605,322...56,622,418 		JBrowse link
G ALPK1 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 4:104,786,721...104,931,981
Ensembl chr 4:115,430,258...115,495,026 		JBrowse link
G APOA1 apolipoprotein A1 ISO RGD PMID:9829487 RGD:2313960 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G APOA2 apolipoprotein A2 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum RGD PMID:9829487 PMID:11126402 RGD:2313958 RGD:2313960 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOB apolipoprotein B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19324028 RGD:2313979 NCBI chr2A:20,986,464...21,029,004
Ensembl chr2A:21,100,356...21,145,129 		JBrowse link
G APOC1 apolipoprotein C1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:very-low-density lipoprotein particle RGD PMID:12753304 RGD:2313950
G APOC3 apolipoprotein C3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-455T>C RGD PMID:16813599 RGD:2306755 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G APOE apolipoprotein E no_association
susceptibility		 ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, type 1;
DNA:missense mutations, haplotype:cds:p.C112R, p.R158C (human)		 RGD PMID:11495633 PMID:21127830 PMID:22859852 RGD:6902935 RGD:6903840 RGD:7771553 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G APOH apolipoprotein H ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:11302005 RGD:2313989 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483 		JBrowse link
G AQP2 aquaporin 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased secretion:urine RGD PMID:12218327 RGD:2314343 NCBI chr12:38,796,300...38,804,559
Ensembl chr12:39,690,289...39,698,397 		JBrowse link
G ARG2 arginase 2 ISO RGD PMID:21926276 RGD:6902923 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962 		JBrowse link
G ASIP agouti signaling protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:37769864 NCBI chr20:30,583,038...30,592,726
Ensembl chr20:31,718,169...31,727,217 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta treatment ISO mRNA:decreased expression:renal glomerulus (rat) RGD PMID:22591908 RGD:13792578 NCBI chr12:32,264,570...32,272,419
Ensembl chr12:32,519,749...32,527,753 		JBrowse link
G AXL AXL receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472 NCBI chr19:38,211,555...38,254,464
Ensembl chr19:46,719,615...46,761,747 		JBrowse link
G AZIN1 antizyme inhibitor 1 treatment ISO RGD PMID:26751697 RGD:14700801 NCBI chr 8:99,483,027...99,521,151
Ensembl chr 8:101,639,950...101,678,604 		JBrowse link
G BDKRB2 bradykinin receptor B2 susceptibility ISO associated with Diabetes Mellitus, Experimental RGD PMID:17596525 RGD:2313335 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253 		JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:20557422 RGD:4891134 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239 		JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:kidney RGD PMID:21866636 RGD:6483069 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO associated with Diabetes Mellitus, Type2; protein:increased expression:serum: RGD PMID:9347246 RGD:7207424 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432 		JBrowse link
G BMP7 bone morphogenetic protein 7 ISO RGD PMID:17437042 RGD:2289036 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021 		JBrowse link
G C3 complement C3 ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Type 1; protein:increased expression:kidney:		 RGD PMID:19200691 PMID:25662584 RGD:11040807 RGD:7183082 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699 		JBrowse link
G C5 complement C5 ISO associated with Diabetes Mellitus, Type 2 RGD PMID:25662584 RGD:11040807 NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B treatment ISO RGD PMID:27273361 RGD:13506726 NCBI chr 9:108,989,621...109,256,841 JBrowse link
G CAPN10 calpain 10 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22012129 RGD:7247733 NCBI chr2B:127,838,477...127,851,334
Ensembl chr2B:246,645,630...246,679,169 		JBrowse link
G CASP3 caspase 3 treatment ISO associated with type 2 diabetes mellitus
associated with Diabetes Mellitus, Experimental;protein:increased activity:kidney
associated with Diabetes Mellitus, Experimental 		RGD PMID:19601660 PMID:28456626 PMID:29606028 RGD:13782304 RGD:13792586 RGD:2311440 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CASP7 caspase 7 treatment ISO associated with type 2 diabetes mellitus RGD PMID:28456626 RGD:13782304 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626 		JBrowse link
G CASP8 caspase 8 treatment ISO associated with Diabetes Mellitus, Experimental
associated with type 2 diabetes mellitus		 RGD PMID:28456626 PMID:29606028 RGD:13782304 RGD:13792586 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468 		JBrowse link
G CASP9 caspase 9 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:29606028 PMID:30038056 RGD:13782342 RGD:13792586 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G CAT catalase ISO associated with experimentally induced diabetes
rat gene in db/db mice		 RGD PMID:20299359 PMID:21525431 PMID:21686137 PMID:22315314 RGD:7205651 RGD:7205662 RGD:7205665 RGD:7205676 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160 		JBrowse link
G CAV1 caveolin 1 ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 disease_progression
susceptibility		 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16374426 PMID:17968528 PMID:18031723 PMID:19097668 PMID:19369290 More... RGD:2306979 RGD:2306980 RGD:2306982 RGD:2306989 RGD:2306991 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17664181 RGD:7483629 NCBI chr2B:115,052,768...115,056,479
Ensembl chr2B:233,862,505...233,866,225 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-28C>G
associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:urine		 RGD PMID:12610055 PMID:18326229 RGD:2307063 RGD:2307107 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
G CCN2 cellular communication network factor 2 ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney, glomerulus (rat)
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat)		 RGD PMID:19065061 PMID:19895808 RGD:2314366 RGD:2314604 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G CCNE1 cyclin E1 ISO protein:increased expression:kidney RGD PMID:17825795 RGD:2289273 NCBI chr19:26,739,285...26,751,630
Ensembl chr19:35,496,700...35,510,295 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 no_association ISO associated with Diabetes Mellitus, Insulin-Dependent
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.V64I (human)		 RGD PMID:11756347 PMID:17631861 RGD:2313558 RGD:2313563 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :59029G>A (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:59029G>A (human)		 RGD PMID:12610055 PMID:17428349 RGD:2307107 RGD:8549756 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) ISO protein:increased expression:renal proximal tubule, endothelial cell RGD PMID:15737001 RGD:2307215 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865 		JBrowse link
G CD38 CD38 molecule ISO associated with Diabetes Mellitus
associated with Diabetes Mellitus, Experimental		 RGD PMID:19073639 PMID:19300526 RGD:2307227 RGD:2307228 NCBI chr 4:10,228,803...10,295,129
Ensembl chr 4:15,525,835...15,587,677 		JBrowse link
G CD40LG CD40 ligand ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:serum RGD PMID:18756582 RGD:2314208 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27652271 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:increased expression:kidney
mRNA, protein:increased expression:kidney, glomerulus		 RGD PMID:15698433 PMID:16805985 RGD:2293619 RGD:2293628 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541 		JBrowse link
G CFL1 cofilin 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:renal glomerulus (rat) RGD PMID:24726496 RGD:11570419 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806 		JBrowse link
G CLU clusterin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:18949565 RGD:9068414 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G CNDP1 carnosine dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:17942768 PMID:21393041 PMID:21573905 RGD:7207213 NCBI chr18:67,920,453...67,982,843
Ensembl chr18:71,162,331...71,188,879
Ensembl chr18:71,162,331...71,188,879 		JBrowse link
G CNDP2 carnosine dipeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21573905 NCBI chr18:67,882,189...67,907,094
Ensembl chr18:71,162,331...71,188,879 		JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus (rat) RGD PMID:22903132 RGD:8552684 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G COL1A2 collagen type I alpha 2 chain ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 7:86,344,657...86,381,282
Ensembl chr 7:99,935,185...99,971,803 		JBrowse link
G COL4A1 collagen type IV alpha 1 chain ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA:increased expression:kidney		 RGD
CTD		 PMID:17582205 PMID:18682491 PMID:19466391 PMID:27997345 RGD:2311340 RGD:2311342 NCBI chr13:91,282,617...91,440,187
Ensembl chr13:110,407,009...110,562,529 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr2B:124,554,478...124,644,482 JBrowse link
G CPB2 carboxypeptidase B2 susceptibility ISO protein:increased expression:plasma
DNA:SNP:cds:1040C>T(human)		 RGD PMID:12574207 PMID:22932273 RGD:7243116 RGD:7243123 NCBI chr13:26,926,788...26,979,767 JBrowse link
G CREB1 cAMP responsive element binding protein 1 susceptibility ISO RGD PMID:15862029 RGD:10059365 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130 		JBrowse link
G CRP C-reactive protein disease_progression ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2;protein:increased expression:urine		 RGD PMID:22590912 PMID:22885250 RGD:6906965 RGD:6906967 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CSF1R colony stimulating factor 1 receptor disease_progression ISO associated with Diabetes Mellitus, Type 2
mRNA,protein:increased expression:kidney (rat)		 RGD PMID:19466391 PMID:32141565 RGD:151665767 RGD:2311340 NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415 		JBrowse link
G CST3 cystatin C ISO protein:increased expression:plasma (rat)
protein:increased expression:serum (human)		 RGD PMID:18946178 PMID:19132849 RGD:2314297 RGD:2314328 NCBI chr20:23,583,043...23,587,399
Ensembl chr20:23,935,942...23,940,425 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:plasma: RGD PMID:18026823 RGD:2312302 NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498 		JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:28468961 NCBI chr11:1,789,326...1,800,524 JBrowse link
G CUBN cubilin ISO RGD PMID:17037740 RGD:1599655 NCBI chr10:17,141,464...17,446,867
Ensembl chr10:17,415,551...17,719,129 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent		 RGD PMID:17425653 PMID:19073786 RGD:2311357 RGD:2311359 NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:22791342 RGD:7257674 NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-344C>T (human) RGD PMID:16672053 RGD:2307295 NCBI chr 8:139,622,632...139,630,014
Ensembl chr 8:142,666,534...142,672,575 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22301628 RGD:7257708 NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO associated with Diabetes Mellitus, Experimental; RGD PMID:21742052 RGD:7243153 NCBI chr 1:59,151,079...59,184,625
Ensembl chr 1:60,856,269...60,889,810 		JBrowse link
G DCN decorin ISO associated with Diabetes Mellitus, Insulin-Dependent;mRNA, protein:decreased expression:kidney cortex, glomerulus
protein:increased expression:plasma, urine
associated with Diabetes Mellitus, Experimental		 RGD PMID:11259366 PMID:12187087 PMID:16868749 PMID:17884968 RGD:2311411 RGD:2311412 RGD:2311415 RGD:2311416 NCBI chr12:88,678,791...88,715,677
Ensembl chr12:91,994,129...92,031,413 		JBrowse link
G DGKH diacylglycerol kinase eta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr13:23,221,391...23,413,541 JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20019166 RGD:6907383 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776 		JBrowse link
G EDN1 endothelin 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased secretion:plasma (human) RGD PMID:18346810 RGD:2313284 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545 		JBrowse link
G EDNRA endothelin receptor type A ISO associated with Diabetes Mellitus, Experimental RGD PMID:21191784 RGD:4892326 NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497 		JBrowse link
G EGF epidermal growth factor ISO RGD PMID:17475821 RGD:6906912 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460 		JBrowse link
G ELMO1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17942768 NCBI chr 7:37,493,854...38,085,555 JBrowse link
G ENG endoglin ISO associated with Diabetes Mellitus, Insulin-Dependent; mRNA:increased expression:kidney RGD PMID:19395281 RGD:2313795 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641 		JBrowse link
G ENPEP glutamyl aminopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28468961 NCBI chr 4:102,969,397...103,056,978
Ensembl chr 4:113,532,126...113,620,654 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:19506043 RGD:6906926 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644 		JBrowse link
G EP300 E1A binding protein p300 treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat)		 RGD PMID:19268536 RGD:2311716 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2		 RGD PMID:17914354 PMID:17967803 RGD:10395374 RGD:10395377 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21832210 RGD:5688728 NCBI chr 8:26,761,090...26,818,436
Ensembl chr 8:23,964,094...24,017,749 		JBrowse link
G EPO erythropoietin ISO associated with Diabetes Mellitus, Experimental;
Protein:decreased expression:serum
DNA:snp:promoter:-1125T>G(rs1617640)(human)		 RGD PMID:18458324 PMID:19356735 PMID:19619913 RGD:2313832 RGD:2313833 RGD:2313838 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney: RGD PMID:10749885 RGD:9685546 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G ESR1 estrogen receptor 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:glomerulus
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:snps:introns: multiple(human)
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney		 RGD PMID:15550505 PMID:16464734 PMID:18305958 RGD:2314005 RGD:2314020 RGD:2314023 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551 		JBrowse link
G F2 coagulation factor II, thrombin disease_progression ISO protein:increased expression:plasma (human)
DNA:polymorphism: :20210G>A(human)		 RGD PMID:14983223 PMID:21574459 PMID:21955218 RGD:2313643 RGD:6893574 RGD:6893575 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:15004866 RGD:2313863 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G FABP2 fatty acid binding protein 2 ISO DNA:polymorphism:CDS:amino acid A54T, in a Brazilian population RGD PMID:16249461 RGD:1578457 NCBI chr 4:111,505,269...111,510,197
Ensembl chr 4:122,055,544...122,060,461 		JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental;protein:increased expression:renal distal tubule (rat)
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney		 RGD PMID:12861046 PMID:17851466 PMID:18287563 RGD:2312739 RGD:2315705 RGD:8686421 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
G FASLG Fas ligand ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney RGD PMID:17851466 RGD:2315705 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281 		JBrowse link
G FBN1 fibrillin 1 onset ISO associated with Diabetes Mellitus, Experimental RGD PMID:16380460 PMID:16395273 RGD:7365077 RGD:7365080 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111 		JBrowse link
G FBXW12 F-box and WD repeat domain containing 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36073553 NCBI chr 3:48,290,904...48,318,318 JBrowse link
G FGF2 fibroblast growth factor 2 ISO mRNA:increased expression:kidney RGD PMID:19279131 RGD:2315842 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G FGF21 fibroblast growth factor 21 ISO protein:increased expression:serum: RGD PMID:25625802 RGD:10401920 NCBI chr19:45,755,466...45,758,472 JBrowse link
G FGF23 fibroblast growth factor 23 severity ISO mRNA,protein:increased expression:kidney: RGD PMID:23967103 RGD:10044235 NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine RGD PMID:15610240 RGD:2313731 NCBI chr13:9,584,850...9,779,542 JBrowse link
G FMOD fibromodulin ISO associated with Diabetes Mellitus, Insulin-Dependent;mRNA:decreased expression:kidney cortex
mRNA,protein:increased expression:Kidney Glomerulus		 RGD PMID:11259366 PMID:16868749 RGD:2311412 RGD:2311416 NCBI chr 1:178,942,472...178,953,158
Ensembl chr 1:183,238,130...183,244,074 		JBrowse link
G FN1 fibronectin 1 treatment ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:nephron tubule (human)
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney
protein:increased expression:kidney cortex:		 CTD
RGD		 PMID:16301823 PMID:22736507 PMID:24413998 PMID:35592524 RGD:10402169 RGD:401851916 RGD:7206843 NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase susceptibility ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs7204609 (human)
associated with type 2 diabetes mellitus;DNA:SNPs: :rs1121980, rs1421085, rs17817449 (human)
associated with diabetes mellitus;DNA:SNP: :rs17817449 (human)		 RGD PMID:29154870 PMID:29410390 PMID:34134115 RGD:329813082 RGD:329813084 RGD:329901856 NCBI chr16:33,939,300...34,343,419
Ensembl chr16:53,023,425...53,490,231 		JBrowse link
G FUCA1 alpha-L-fucosidase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased activity;urine RGD PMID:8343614 RGD:2315943 NCBI chr 1:23,039,126...23,060,514
Ensembl chr 1:24,022,967...24,043,850 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO associated with Hypertension RGD PMID:21987533 RGD:10449128 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674 		JBrowse link
G GAS6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472 Ensembl chr13:113,968,843...114,009,562 JBrowse link
G GATM glycine amidinotransferase ISO RGD PMID:26364511 RGD:329961310 NCBI chr15:24,309,045...24,326,673
Ensembl chr15:42,639,597...42,657,209 		JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 ISO RGD PMID:9519709 RGD:2313353 NCBI chr2A:69,363,229...69,430,182
Ensembl chr2A:70,488,763...70,551,141 		JBrowse link
G GFPT2 glutamine-fructose-6-phosphate transaminase 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP:3' utr RGD PMID:14764791 RGD:2307362 NCBI chr 5:175,504,272...175,558,610
Ensembl chr 5:182,815,719...182,869,823 		JBrowse link
G GHR growth hormone receptor susceptibility ISO associated with Diabetes Mellitus
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney		 RGD PMID:10541297 PMID:10614635 PMID:10990443 PMID:15066219 RGD:2307364 RGD:2307368 RGD:2307369 RGD:2307370 NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor ISO RGD PMID:19211686 RGD:2306734 NCBI chr19:42,673,553...42,688,059
Ensembl chr19:51,213,090...51,225,293 		JBrowse link
G GLO1 glyoxalase I ISO DNA:SNP:promoter:-7C>T (human) RGD PMID:21738003 RGD:7242569 NCBI chr 6:38,247,881...38,275,098
Ensembl chr 6:39,434,746...39,461,971 		JBrowse link
G GPX1 glutathione peroxidase 1 treatment ISO associated with Diabetes Mellitus, Type 1
associated with Experimental Diabetes Mellitus
protein:increased expression:glomerulus		 RGD PMID:16249459 PMID:17609286 PMID:32592386 RGD:11068479 RGD:2306609 RGD:401827869 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G GPX3 glutathione peroxidase 3 treatment ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:serum (human)
associated with Experimental Diabetes Mellitus		 RGD PMID:17269729 PMID:32592386 RGD:2312635 RGD:401827869 NCBI chr 5:146,447,939...146,456,476 JBrowse link
G GRK2 G protein-coupled receptor kinase 2 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066 		JBrowse link
G GRK3 G protein-coupled receptor kinase 3 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr22:6,579,664...6,789,846
Ensembl chr22:24,353,533...24,509,560 		JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO protein:decreased expression:cortex of kidney (rat) RGD PMID:23196710 RGD:13792785 NCBI chr 4:3,106,064...3,181,270
Ensembl chr 4:3,008,126...3,083,094 		JBrowse link
G GRK6 G protein-coupled receptor kinase 6 treatment ISO RGD PMID:23196710 RGD:13792785 NCBI chr 5:172,704,978...172,744,907
Ensembl chr 5:179,790,662...179,807,410 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO RGD PMID:26888388 RGD:13792773 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771 		JBrowse link
G GSR glutathione-disulfide reductase treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;protein:decreased activity:kidney		 RGD PMID:23626958 PMID:24947049 RGD:10401899 RGD:7257582 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 no_association ISO associated with Diabetes Mellitus, Type 1;DNA:deletion:cds: (human) RGD PMID:19752172 RGD:7495818 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G HAS2 hyaluronan synthase 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal medulla RGD PMID:18441392 RGD:9588630 NCBI chr 8:118,313,186...118,342,160
Ensembl chr 8:121,072,154...121,089,365 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression ISO associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
protein:increased expression:plasma
associated with Diabetes mellitus, Type 1;		 RGD PMID:20980978 PMID:22015481 PMID:22997966 RGD:7245497 RGD:7245960 RGD:7246890 NCBI chr 5:152,429,337...152,459,800
Ensembl chr 5:158,413,073...158,442,481 		JBrowse link
G HDAC2 histone deacetylase 2 ISO mRNA,protein:increased expression:kidney: RGD PMID:24717296 RGD:9590311 NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004 		JBrowse link
G HDAC4 histone deacetylase 4 treatment ISO mRNA,protein:increased expression:kidney: RGD PMID:24717296 RGD:9590311 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054 		JBrowse link
G HDAC5 histone deacetylase 5 ISO mRNA,protein:increased expression:kidney: RGD PMID:24717296 RGD:9590311 NCBI chr17:13,273,052...13,319,695
Ensembl chr17:13,446,836...13,479,140 		JBrowse link
G HFE homeostatic iron regulator ISO associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:15347835 RGD:8694362 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G HGF hepatocyte growth factor ISO RGD PMID:16340242 RGD:2313567 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2		 RGD PMID:17914354 PMID:17967803 RGD:10395374 RGD:10395377 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21849637 RGD:10755581 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 susceptibility ISO DNA:SNO:intron: (rs17389016, rs11799643) (human) RGD PMID:32453474 RGD:329902062 NCBI chr 1:185,262,599...185,311,417
Ensembl chr 1:190,086,449...190,116,765 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A ISO associated with Diabetes Mellitus, Type 2 RGD PMID:18518860 RGD:7242747 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B ISO RGD PMID:18518860 RGD:7242747 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney RGD PMID:19301230 RGD:2311449 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:17330940 RGD:7242762 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO mRNA,protein:increased expression:glomerulus:
protein:increased expression:glomerulus, podocyte:		 RGD PMID:21931298 RGD:10402764 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO associated with Diabetes Mellitus Type 2;
associated with Diabetes Mellitus, Experimental;		 RGD PMID:12213354 PMID:18175064 RGD:7257686 RGD:7257687 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.K469E (rs5498) (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney (mouse)		 RGD PMID:18299691 PMID:18505543 PMID:19246972 PMID:20447389 RGD:2312766 RGD:2313470 RGD:2313475 RGD:4145414 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605 		JBrowse link
G IFNG interferon gamma ISO mRNA, protein:increased expression:kidney, T cell RGD PMID:22286547 RGD:6893364 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829 		JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:decreased expression:serum
associated with Diabetes Mellitus, Experimental;protein:decreased expression:serum (rat)		 RGD PMID:10444029 PMID:17194636 RGD:12904967 RGD:2313764 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO mRNA,protein:increased expression:kidney: RGD PMID:19008912 RGD:10046022 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G IGF2 insulin like growth factor 2 ISO associated with Diabetes Mellitus, Type 2;
associated with Diabetes Mellitus, Type 2; mRNA:decreased expression:neural tissue, liver:
associates with Diabetes Mellitus; mRNA:decreased expression:brain:		 RGD PMID:8764603 PMID:9336345 RGD:5510019 RGD:5510022 NCBI chr11:2,170,190...2,199,442
Ensembl chr11:2,202,743...2,228,890 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr 7:46,538,566...46,545,536
Ensembl chr 7:46,658,097...46,662,584 		JBrowse link
G IL10 interleukin 10 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphisms:promoter:g.-1082G>A, g.-819C>T, g.-592C>A (human) RGD PMID:19031431 RGD:2308943 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371 		JBrowse link
G IL1B interleukin 1 beta ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2		 RGD PMID:19769609 PMID:22086159 RGD:7175266 RGD:7175519 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL1RN interleukin 1 receptor antagonist no_association
susceptibility		 ISO associated with Diabetes Mellitus, Type 2; DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:16174285 PMID:17286233 RGD:6907371 RGD:6909120 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
G IL6 interleukin 6 susceptibility ISO associated with Diabetes Mellitus, Type1;DNA:polymorphism:promoter:-174G>C(human)
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney (rat)		 RGD PMID:18716362 PMID:19052104 PMID:19542902 RGD:2307281 RGD:2307282 RGD:7829816 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G INS insulin resistance ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:2143390 PMID:7713310 PMID:7987072 PMID:22068113 RGD:6902908 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G IRS2 insulin receptor substrate 2 ISO mRNA:increased expression:kidney tubule: RGD PMID:23617393 RGD:7257702 NCBI chr13:90,886,095...90,917,724 JBrowse link
G ITGA2 integrin subunit alpha 2 severity ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:mesangial cell (human) RGD PMID:8989742 RGD:2307420 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720 		JBrowse link
G ITGB2 integrin subunit beta 2 ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr21:31,181,228...31,216,033
Ensembl chr21:44,470,999...44,505,963 		JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO RGD PMID:24733189 PMID:29425253 RGD:329955448 RGD:329969879 NCBI chr19:40,715,621...40,735,025
Ensembl chr19:49,321,403...49,335,900 		JBrowse link
G KDM6A lysine demethylase 6A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:kidney (mouse) RGD PMID:23508046 RGD:9587808 NCBI chr  X:37,313,000...37,548,630
Ensembl chr  X:45,127,382...45,362,029 		JBrowse link
G KDR kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18630688 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO RGD PMID:21439372 RGD:6893386 NCBI chr19:10,037,544...10,055,091
Ensembl chr19:10,701,303...10,717,604 		JBrowse link
G KL klotho treatment ISO protein:decreased expression:kidney: RGD PMID:24136780 RGD:10403079 NCBI chr13:14,272,463...14,321,122
Ensembl chr13:32,702,336...32,751,458 		JBrowse link
G KLK1 kallikrein 1 ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:17272402 PMID:19516248 RGD:1641794 NCBI chr19:47,784,368...47,789,004
Ensembl chr19:56,677,579...56,682,216 		JBrowse link
G KLKB1 kallikrein B1 disease_progression ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G KNG1 kininogen 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :7965C>T (human) RGD PMID:17065357 RGD:2311541 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149 		JBrowse link
G LAMB2 laminin subunit beta 2 ISO RGD PMID:19864299 RGD:7207449 NCBI chr 3:49,045,419...49,057,340
Ensembl chr 3:50,125,460...50,137,074 		JBrowse link
G LCN2 lipocalin 2 ISO protein:increased expression:urine
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:		 RGD PMID:22015481 PMID:22997966 RGD:7245497 RGD:7245960 NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798 		JBrowse link
G LEP leptin ISO RGD PMID:22773754 RGD:6907074 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519 		JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism
DNA:mutations:cds: : (rat)		 CTD
RGD		 PMID:28130181 PMID:28746409 PMID:29988851 PMID:36066211 RGD:401965413 NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768 		JBrowse link
G LMNA lamin A/C ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:cds:1908C>T (human) RGD PMID:16117820 RGD:2306095 NCBI chr 1:131,456,819...131,482,275
Ensembl chr 1:135,253,700...135,311,539 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:1789335 RGD:2311543 NCBI chr 5:92,247,060...92,348,900
Ensembl chr 5:97,842,110...97,893,876 		JBrowse link
G LOC100968989 HLA class II histocompatibility antigen, DM alpha chain ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 6:32,518,060...32,537,989
Ensembl chr 6:33,634,123...33,637,988 		JBrowse link
G LOC100980531 eotaxin ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21113841 RGD:5683918 NCBI chr17:22,495,737...22,515,144
Ensembl chr17:22,806,076...22,808,345
Ensembl chr17:22,806,076...22,808,345 		JBrowse link
G LOC100982859 class I histocompatibility antigen, Gogo-B*0101 alpha chain ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067 		JBrowse link
G LOC100986914 cytochrome b-245 light chain ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :242C>T (human) RGD PMID:14747204 RGD:8695982 NCBI chr16:69,356,396...69,364,225
Ensembl chr16:89,016,349...89,024,719 		JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417 		JBrowse link
G LOC100991392 serine protease 2 ISO protein:increased expression:urine RGD PMID:18428024 RGD:2324899 NCBI chr 7:134,761,471...134,765,816
Ensembl chr 7:147,223,606...147,257,587 		JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387 		JBrowse link
G LPL lipoprotein lipase susceptibility ISO RGD PMID:16813599 RGD:2306755 NCBI chr 8:19,164,541...19,193,100
Ensembl chr 8:16,113,415...16,142,966 		JBrowse link
G LTA lymphotoxin alpha ISO DNA:polymorphism RGD PMID:18575614 RGD:2313255 NCBI chr 6:31,233,411...31,235,409
Ensembl chr 6:32,123,353...32,125,375 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO RGD PMID:19923143 RGD:7243957 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased activity:kidney RGD PMID:19066844 RGD:2311566 NCBI chr 6:35,586,847...35,683,041
Ensembl chr 6:36,788,233...36,871,114 		JBrowse link
G MDK midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:17607302 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254 		JBrowse link
G MFN2 mitofusin 2 treatment ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:26123583 PMID:27997345 RGD:11053290 RGD:12910740 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077 		JBrowse link
G MHC-DMB HLA class II histocompatibility antigen, DM beta chain ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 6:32,504,074...32,510,669
Ensembl chr 6:33,619,870...33,625,685 		JBrowse link
G MLLT3 MLLT3 super elongation complex subunit treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23077601 RGD:9686143 NCBI chr 9:20,140,160...20,417,327
Ensembl chr 9:20,800,393...21,073,046 		JBrowse link
G MMP12 matrix metallopeptidase 12 ISO RGD PMID:21277817 RGD:7241216 NCBI chr11:97,809,644...97,822,063
Ensembl chr11:101,294,475...101,306,762 		JBrowse link
G MMP2 matrix metallopeptidase 2 treatment
ameliorates		 ISO associated with Diabetes Mellitus, Experimental RGD PMID:23384615 PMID:37643020 RGD:13204971 RGD:401827835 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279 		JBrowse link
G MMP3 matrix metallopeptidase 3 ISO protein: decreased expression: glomerulus RGD PMID:9211353 RGD:7241249 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO associated with Diabetes Mellitus, Type 2;DNA:repeat:promoter
associated with Diabetes Mellitus, Experimental		 RGD PMID:11576356 PMID:23384615 RGD:13204971 RGD:8547866 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase no_association
susceptibility		 ISO associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human) RGD PMID:14737040 PMID:18280442 RGD:6893524 RGD:6893576 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419 		JBrowse link
G MTOR mechanistic target of rapamycin kinase susceptibility ISO DNA:SNP,haplotype: :rs7212142(human)
associated with Diabetes Mellitus, Experimental		 RGD PMID:21606597 PMID:23827786 PMID:28536139 RGD:10003168 RGD:13506787 RGD:7245564 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO Associated with Diabetes Mellitus, Type 1;DNA:SNP:cds:66A>G, (rs1801394) (human) RGD PMID:18774994 RGD:6893652 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322 		JBrowse link
G NAT2 N-acetyltransferase 2 ISO associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:10591543 RGD:2311598 NCBI chr 8:17,606,445...17,623,397
Ensembl chr 8:14,575,455...14,576,327 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney,glomerulus		 RGD PMID:22591908 PMID:22903132 RGD:13792578 RGD:8552684 NCBI chr11:47,528,680...47,534,206
Ensembl chr11:48,078,332...48,083,863 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 ISO protein:increased expression:nucleus RGD PMID:26481166 RGD:329337345 NCBI chr18:72,948,067...73,083,180
Ensembl chr18:76,017,454...76,094,453 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:20103708 PMID:21439372 PMID:23064900 RGD:10412718 RGD:6893386 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085 		JBrowse link
G NOS1 nitric oxide synthase 1 treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental		 RGD PMID:10966937 PMID:23548923 RGD:13824991 RGD:7257655 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005 		JBrowse link
G NOS3 nitric oxide synthase 3 no_association
susceptibility
treatment		 ISO associated with Diabetes Mellitus, Type 2;DNA:duplication:intron:IVS4?-?+27 (human)
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10741691 PMID:10868974 PMID:20042665 PMID:29336891 RGD:13504726 RGD:7421530 RGD:7421534 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233 		JBrowse link
G NOX4 NADPH oxidase 4 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney cortex RGD PMID:16135519 PMID:17511984 RGD:2324670 RGD:2324673 NCBI chr11:84,330,362...84,496,755 JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:decreased expression:kidney (mouse)		 RGD PMID:17624267 PMID:21617141 PMID:24173355 PMID:30862474 RGD:38596322 RGD:38596325 RGD:38599008 RGD:7241083 NCBI chr19:32,742,802...32,770,600
Ensembl chr19:41,492,444...41,518,471 		JBrowse link
G NPPA natriuretic peptide A disease_progression
no_association		 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :2238T>C (human)
DNA:polymorphism:intron
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:blood
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma		 RGD PMID:9681733 PMID:10381153 PMID:10404802 PMID:15111511 RGD:2313590 RGD:2313592 RGD:2313593 RGD:7247731 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G NPPB natriuretic peptide B ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:10404802 PMID:16917760 RGD:7247731 RGD:7248603 NCBI chr 1:10,621,416...10,622,960
Ensembl chr 1:11,838,518...11,839,995 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21457706 RGD:11035226 NCBI chr16:50,090,696...50,106,495
Ensembl chr16:69,470,288...69,489,731 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:20557422 RGD:4891134 NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20621183 RGD:11073737 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356 		JBrowse link
G PAX2 paired box 2 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney cortex RGD PMID:15149326 RGD:2316747 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PDGFA platelet derived growth factor subunit A ISO associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:increased expression:kidney RGD PMID:12808179 RGD:2311649 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:glomerulus RGD PMID:15042541 RGD:2311655 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067 		JBrowse link
G PGF placental growth factor disease_progression ISO associated with Diabetes Mellitus, Type 1 RGD PMID:21988672 RGD:6483606 NCBI chr14:55,494,152...55,508,066
Ensembl chr14:74,338,976...74,352,964 		JBrowse link
G PLAT plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16598198 RGD:2311671 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G PLAU plasminogen activator, urokinase ISO mRNA:increased expression:renal glomerulus (rat) RGD PMID:15322501 RGD:1580123 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136 		JBrowse link
G PON1 paraoxonase 1 no_association
susceptibility		 ISO associated with Diabetes Mellitus;DNA:missense mutations:cds:p.L55M, p.Q192R (rs854560, rs662) (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15270786 PMID:19207863 PMID:24100645 PMID:26884296 RGD:2313266 RGD:8547548 RGD:8547572 NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493 		JBrowse link
G PON2 paraoxonase 2 ISO associated with type 1 diabetes mellitus;DNA:missense mutation:cds:p.C311S (human)
associated with type 2 diabetes mellitus;DNA:polymorphisms:multiple		 RGD PMID:11206400 PMID:11918623 RGD:1580218 RGD:2313492 NCBI chr 7:87,362,447...87,392,795
Ensembl chr 7:100,950,074...100,980,433 		JBrowse link
G POSTN periostin ISO mRNA,protein:increased expression:kidney: RGD PMID:22167593 RGD:10040972 NCBI chr13:18,779,297...18,815,207
Ensembl chr13:37,368,030...37,407,212 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent		 CTD
RGD		 PMID:18388116 PMID:18780770 PMID:28182703 RGD:2301845 RGD:2301862 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO DNA:polymorphism:exon:p.G482S (human)
mRNA:decreased expression:kidney (human)		 RGD PMID:19900151 PMID:21784897 RGD:7242027 RGD:7242045 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212 		JBrowse link
G PRKCB protein kinase C beta ISO associated with hypertension;protein:increased expression:glomerular mesangium
mRNA:increased expression:nephron tubule (human)		 RGD PMID:12540629 PMID:35592524 RGD:401851916 RGD:729635 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203 		JBrowse link
G PRKCE protein kinase C epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23159951 RGD:9491822 NCBI chr19:46,691,795...46,705,179
Ensembl chr19:55,610,938...55,623,135 		JBrowse link
G PROS1 protein S severity
treatment		 ISO associated with diabetes mellitus, experimental;mRNA, protein:increased expression:kidney, glomerulus RGD PMID:29511111 RGD:13515131 NCBI chr 3:90,934,641...91,039,059
Ensembl chr 3:97,615,734...97,718,756 		JBrowse link
G PTEN phosphatase and tensin homolog ISO protein:decreased expression:kidney cortex, glomerulus RGD PMID:16804083 RGD:2292546 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G PTGDS prostaglandin D2 synthase susceptibility ISO RGD PMID:15970590 RGD:1642581 NCBI chr 9:108,037,994...108,042,136
Ensembl chr 9:137,006,601...137,009,680 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17112505 PMID:21441310 RGD:5135032 RGD:5688268 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G PTH parathyroid hormone ISO DNA:snps:exon, intron:g.350C>A, g.IVS2+56G>A (rs6256, rs6254) (human) RGD PMID:22777106 RGD:7242744 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802 		JBrowse link
G RBP4 retinol binding protein 4 disease_progression ISO associated with type 2 diabetes mellitus; protein:increased expression:blood plasma, urine (human) RGD PMID:17568782 RGD:329845581 NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17900838 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868 		JBrowse link
G REN renin ISO RGD PMID:15489960 RGD:1579795 NCBI chr 1:179,757,653...179,769,530
Ensembl chr 1:184,046,117...184,057,393 		JBrowse link
G RETN resistin ISO RGD PMID:21425555 RGD:7207159 NCBI chr19:6,958,536...6,960,032
Ensembl chr19:7,812,942...7,814,909 		JBrowse link
G RHOA ras homolog family member A ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G SELP selectin P severity ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney, serum		 RGD PMID:18026823 PMID:18471420 RGD:2312294 RGD:2312302 NCBI chr 1:145,071,094...145,112,851
Ensembl chr 1:148,793,677...148,834,701 		JBrowse link
G SERPINB7 serpin family B member 7 ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2;DNA:SNP:intron:rs1720843 (human)		 RGD PMID:16443768 PMID:19690890 RGD:7207374 RGD:7207378 NCBI chr18:57,112,242...57,164,213
Ensembl chr18:60,445,135...60,475,165 		JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO associated with Diabetes Mellitus, Experimental
associate with Diabetes Mellitus, Type 1;protein:increased expression:plasma (human)
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus, mesangial cell (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10809802 PMID:15322501 PMID:18682491 PMID:26712211 RGD:11073694 RGD:1580123 RGD:8547711 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO human protein in a mouse model
mRNA, protein:decreased expression:renal cortex, renal medulla (rat)
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma (human)		 RGD PMID:15616035 PMID:18523656 PMID:23884140 RGD:1359799 RGD:8554865 RGD:8554896 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:SNP:exon:g.20882C>T (human)		 RGD PMID:15745834 PMID:22707888 PMID:26337659 RGD:12879466 RGD:12879861 RGD:2312305 NCBI chr 1:42,224,273...42,257,184
Ensembl chr 1:43,600,733...43,634,143 		JBrowse link
G SMAD6 SMAD family member 6 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17437042 RGD:2289036 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 treatment ISO RGD PMID:31599432 RGD:151347182 NCBI chr16:10,196,432...10,198,205 JBrowse link
G SOD1 superoxide dismutase 1 ISO protein:decreased expression:kidney
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple
human gene in a mouse model		 RGD PMID:11522679 PMID:17914031 PMID:19470681 RGD:2312361 RGD:2312365 RGD:8655571 NCBI chr21:18,029,831...18,037,526 JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:17192491 PMID:24819633 RGD:7175540 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960 		JBrowse link
G SOD3 superoxide dismutase 3 ISO protein:decreased expression:kidney RGD PMID:19470681 RGD:2312361 NCBI chr 4:19,195,941...19,201,298
Ensembl chr 4:24,485,059...24,485,781 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:decreased expression:kidney RGD PMID:8569083 RGD:2300072 NCBI chr 5:147,087,903...147,112,466
Ensembl chr 5:153,090,181...153,115,750 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:12032186 RGD:1581328 NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:kidney
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental		 RGD PMID:16046298 PMID:16936198 PMID:17961514 PMID:18613221 RGD:1581418 RGD:2308806 RGD:2308811 RGD:2308815 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:kidney
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney		 RGD PMID:16046298 PMID:16936198 RGD:1581418 RGD:2308815 NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067 		JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP (human) RGD PMID:19506043 RGD:6906926 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281 		JBrowse link
G TF transferrin ISO RGD PMID:23468095 RGD:7244196 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476 		JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:glomerulus
associated with Diabetes Mellitus, Experimental		 CTD
RGD		 PMID:18682491 PMID:19211686 PMID:19960420 PMID:24074026 RGD:2306734 RGD:7394855 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973 		JBrowse link
G TGFBI transforming growth factor beta induced ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12911551 PMID:18682491 RGD:1304421 NCBI chr 5:131,420,403...131,455,265
Ensembl chr 5:137,559,321...137,596,392 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496156 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856 		JBrowse link
G TGIF1 TGFB induced factor homeobox 1 ISO protein:decreased expression:glomerulus (rat) RGD PMID:15153551 RGD:1599409 NCBI chr18:10,819,015...10,830,282
Ensembl chr18:13,128,359...13,139,145 		JBrowse link
G THBS1 thrombospondin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17878288 RGD:2317941 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO mRNA:increased expression:kidney RGD PMID:17491697 RGD:2290407 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
G TINAG tubulointerstitial nephritis antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr 6:53,861,919...53,945,740
Ensembl chr 6:55,499,752...55,581,273 		JBrowse link
G TLR2 toll like receptor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21617141 RGD:7241083 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331 		JBrowse link
G TLR4 toll like receptor 4 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22021706 RGD:7207902 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNF tumor necrosis factor ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:increased expression:urine		 RGD PMID:12969138 PMID:16141456 PMID:16336586 PMID:21441310 RGD:1580208 RGD:1580296 RGD:1580311 RGD:5135032 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TNFAIP1 TNF alpha induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr17:28,427,448...28,438,826
Ensembl chr17:28,929,788...28,941,278 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b treatment
disease_progression		 ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Type 1		 RGD PMID:18719882 PMID:20727867 RGD:7205493 RGD:7205514 NCBI chr 8:115,614,778...115,643,387
Ensembl chr 8:118,134,305...118,162,422 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2		 RGD PMID:19073786 PMID:22042131 RGD:2311357 RGD:7245547 NCBI chr12:6,457,617...6,470,969
Ensembl chr12:6,374,257...6,387,613 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B onset ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 1;protein:increased expression:serum		 RGD PMID:16408124 PMID:19073786 PMID:22266664 RGD:2311357 RGD:7245476 RGD:7245529 NCBI chr 1:10,915,743...10,957,765
Ensembl chr 1:12,130,663...12,172,646 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO protein:increased expression:kidney RGD PMID:18287563 RGD:2312739 NCBI chr 3:169,512,491...169,530,706
Ensembl chr 3:177,694,021...177,712,137 		JBrowse link
G TP53 tumor protein p53 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17901943 RGD:2290561 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 treatment ISO protein:increased expression:kidney interstitium RGD PMID:29331667 PMID:30478987 RGD:127229931 RGD:127284861 NCBI chr 6:40,861,283...40,874,446
Ensembl chr 6:42,163,337...42,183,091 		JBrowse link
G TRIP10 thyroid hormone receptor interactor 10 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26097534 RGD:11535148 NCBI chr19:5,772,225...5,784,078
Ensembl chr19:6,693,646...6,705,399 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr 3:139,757,408...139,841,006
Ensembl chr 3:147,349,056...147,432,332 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 treatment
induces		 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22673147 PMID:29923767 RGD:149735534 RGD:7247584 NCBI chr11:96,414,498...96,551,670
Ensembl chr11:99,919,410...100,050,685 		JBrowse link
G TXNIP thioredoxin interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17582205 NCBI chr 1:121,763,312...121,767,468 JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:urine (human) RGD PMID:17634209 RGD:2311211 NCBI chr19:18,040,946...18,052,445 JBrowse link
G UCP1 uncoupling protein 1 no_association ISO DNA:SNP: :-3826A>G (human) RGD PMID:15120704 RGD:7247625 NCBI chr 4:132,921,033...132,930,714
Ensembl chr 4:144,230,858...144,240,178 		JBrowse link
G UCP2 uncoupling protein 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22848482 RGD:7175295 NCBI chr11:69,047,397...69,056,056
Ensembl chr11:72,354,529...72,363,185 		JBrowse link
G UTS2 urotensin 2 disease_progression ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:urine
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
mRNA:increased expression:kidney		 RGD PMID:15476950 PMID:15492948 PMID:18796544 RGD:2306786 RGD:2306805 RGD:2306806 NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688 		JBrowse link
G UTS2R urotensin 2 receptor ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
mRNA:increased expression:kidney		 RGD PMID:15492948 PMID:18796544 RGD:2306786 RGD:2306805 NCBI chr17:76,783,432...76,788,639
Ensembl chr17:82,592,312...82,593,702 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO associated with Diabetes Mellitus,Type 1;protein:increased expression:plasma:
protein:increased expression:kidney		 RGD PMID:20138682 PMID:23303408 RGD:7240523 RGD:7241237 NCBI chr 1:103,377,815...103,395,118
Ensembl chr 1:102,091,336...102,107,732 		JBrowse link
G VDAC1 voltage dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005 		JBrowse link
G VDAC2 voltage dependent anion channel 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr10:71,739,395...71,763,835 JBrowse link
G VEGFA vascular endothelial growth factor A ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15610240 PMID:18630688 RGD:2313731 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
G VTN vitronectin ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:glomerulus RGD PMID:11728964 RGD:10003096 NCBI chr17:28,403,813...28,407,202
Ensembl chr17:28,906,508...28,909,583 		JBrowse link
G VWF von Willebrand factor ISO mRNA:increased expression:nephron tubule (human) RGD PMID:35592524 RGD:401851916 NCBI chr12:6,073,836...6,249,806
Ensembl chr12:5,990,612...6,165,153 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental		 RGD PMID:19458127 PMID:22302365 RGD:7247644 RGD:7247651 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455 		JBrowse link
G XYLT1 xylosyltransferase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:missense mutation:cds:p.A115S (human) RGD PMID:17003309 RGD:2313138 NCBI chr16:20,078,904...20,447,268
Ensembl chr16:17,222,447...17,470,818 		JBrowse link
G YY1 YY1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:35445903 NCBI chr14:80,859,491...80,903,651 JBrowse link
diabetic neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2B adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism (human) RGD PMID:17516297 RGD:2313542 NCBI chr2A:103,198,432...103,202,506
Ensembl chr2A:97,040,126...97,041,472 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22171162 RGD:8695979 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B susceptibility ISO associated with Diabetes Mellitus, Type 1;DNA:repeat:promoter:g.(CA)n (human)
associated with Diabetes Mellitus, Experimental		 RGD PMID:9489533 PMID:16900242 RGD:1626089 RGD:8548642 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15318096 RGD:2311150 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:20724598 RGD:5509623 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24288572 RGD:10053667 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:20587056 RGD:5129222 NCBI chr14:76,885,923...76,894,456 JBrowse link
G BDNF brain derived neurotrophic factor ISO associated with Diabetes Mellitus, Experimental RGD PMID:20557422 RGD:4891134 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239 		JBrowse link
G BECN1 beclin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:25824552 RGD:11561957 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G CASP3 caspase 3 ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental;protein:increased expresssion:sciatic nerve		 CTD
RGD		 PMID:12502508 PMID:19555701 RGD:2311441 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10780678 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160 		JBrowse link
G CAV1 caveolin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:19675140 RGD:8661787 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO associated with Diabetes Mellitus;protein:increased expression:serum RGD PMID:19276232 RGD:2307060 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
G CD63 CD63 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:platelet RGD PMID:10547212 RGD:2314203 NCBI chr12:33,181,896...33,186,123
Ensembl chr12:33,906,314...33,910,595 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20624991 NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18810243 RGD:2314631 NCBI chr 6:86,017,141...86,044,889 JBrowse link
G EPO erythropoietin ISO associated with Diabetes Mellitus, Experimental; RGD PMID:19244253 RGD:2313834 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974 		JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:altered expression:plasma (human) RGD PMID:10468085 RGD:2312401 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:16644707 RGD:2315860 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase susceptibility ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs17817449 (human) RGD PMID:29154870 RGD:329813082 NCBI chr16:33,939,300...34,343,419
Ensembl chr16:53,023,425...53,490,231 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus,Insulin-Dependent;protein:increased activity:serum RGD PMID:11311965 RGD:2315614 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO associated with Diabetes Mellitus, Experimental RGD PMID:19733151 RGD:2313744 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G GRM5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19840219 NCBI chr11:83,514,978...84,077,650
Ensembl chr11:87,107,788...87,868,953 		JBrowse link
G HGF hepatocyte growth factor ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:15734864 PMID:26000320 RGD:2313570 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811 		JBrowse link
G HHIP hedgehog interacting protein ISO RGD PMID:19515211 RGD:11552601 NCBI chr 4:136,989,818...137,085,407
Ensembl chr 4:148,651,597...148,744,619 		JBrowse link
G IFNG interferon gamma ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :874A>T (human) RGD PMID:19608431 RGD:2311489 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829 		JBrowse link
G IGF1 insulin like growth factor 1 treatment ISO protein:decreased expression:serum
associated with Diabetes Mellitus, Experimental		 RGD PMID:17194636 PMID:18545223 PMID:19264110 RGD:2306687 RGD:2313764 RGD:8549454 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IL1B interleukin 1 beta treatment ISO RGD PMID:23280817 RGD:7401217 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G INSR insulin receptor ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental;protein:decreased phosphorylation:sciatic nerve		 CTD
RGD		 PMID:18331706 RGD:2307344 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889 		JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24263156 NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:cerebellum, Purkinje cell RGD PMID:24810053 RGD:13462056 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18579738 RGD:2311567 NCBI chr 6:35,586,847...35,683,041
Ensembl chr 6:36,788,233...36,871,114 		JBrowse link
G MBP myelin basic protein ISO associated with Diabetes Mellitus, Experimental; protein:decreased expression:sciatic nerve: RGD PMID:23735240 RGD:7327194 NCBI chr18:70,369,882...70,526,693
Ensembl chr18:73,629,522...73,755,351 		JBrowse link
G MME membrane metalloendopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20148083 NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20213226 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20213226 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129 		JBrowse link
G MPZ myelin protein zero treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22158827 RGD:9685782 NCBI chr 1:136,691,245...136,720,958
Ensembl chr 1:140,626,039...140,631,273 		JBrowse link
G NGF nerve growth factor ISO mRNA,protein:decreased expression:sciatic nerve RGD PMID:12469361 RGD:5508379 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NGFR nerve growth factor receptor ISO mRNA,protein:decreased expression:dorsal root ganglia (GK/KyoSwe) RGD PMID:12469361 RGD:5508379 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18802679 RGD:2313218 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093 		JBrowse link
G NRG1 neuregulin 1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24288572 RGD:10053667 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977 		JBrowse link
G NTF3 neurotrophin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11779407 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA,protein:decreased expression:dorsal root ganglia RGD PMID:12469361 RGD:5508379 Ensembl chr 1:136,007,476...136,047,355 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:17976390 PMID:21978940 RGD:5510012 RGD:5683915 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356 		JBrowse link
G PGF placental growth factor ISO associated with Diabetes Mellitus, Experimental RGD PMID:21056561 RGD:6483583 NCBI chr14:55,494,152...55,508,066
Ensembl chr14:74,338,976...74,352,964 		JBrowse link
G PLAT plasminogen activator, tissue type ISO RGD PMID:17636064 RGD:2311667 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO mRNA, protein:increased expression:peripheral nerve RGD PMID:17720896 PMID:21951301 RGD:1642588 RGD:5508311 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G RETN resistin ISO associated with Diabetes Mellitus, Type 2 RGD PMID:17919381 RGD:7207161 NCBI chr19:6,958,536...6,960,032
Ensembl chr19:7,812,942...7,814,909 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16696316 NCBI chr 6:131,936,397...132,082,670
Ensembl chr 6:136,033,851...136,180,121 		JBrowse link
G SORD sorbitol dehydrogenase resistance ISO RGD PMID:15755558 RGD:1601362 NCBI chr15:23,971,017...24,025,043 JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 ISO associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:19423844 RGD:2308808 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:dorsal root ganglion
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16696316 PMID:18406405 RGD:2302086 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:dorsal root ganglion RGD PMID:18406405 RGD:2302086 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
G TGFB3 transforming growth factor beta 3 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:sciatic nerve RGD PMID:18406405 RGD:2302086 NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412 		JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO associated with Diabetes Mellitus, Experimental;
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphisms: :p.N299G, p.T399I (human)		 RGD
CTD		 PMID:14693986 PMID:22910613 RGD:2312493 RGD:7777098 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:23280817 RGD:7401217 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:22133672 RGD:10043378 NCBI chr 8:68,551,685...68,605,336
Ensembl chr 8:70,210,352...70,262,627 		JBrowse link
G UCP2 uncoupling protein 2 susceptibility ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism:promoter:-866G>A (rs659366)(human) RGD PMID:16373902 RGD:2313516 NCBI chr11:69,047,397...69,056,056
Ensembl chr11:72,354,529...72,363,185 		JBrowse link
G UCP3 uncoupling protein 3 susceptibility ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism:promoter:-55C>T (human) RGD PMID:16373902 RGD:2313516 NCBI chr11:69,072,143...69,085,424
Ensembl chr11:72,380,180...72,389,274 		JBrowse link
G USP15 ubiquitin specific peptidase 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35478295 NCBI chr12:26,533,441...26,682,964
Ensembl chr12:26,808,337...26,954,099 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19414982 RGD:2312761 NCBI chr 1:103,377,815...103,395,118
Ensembl chr 1:102,091,336...102,107,732 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO associated with Diabetes Mellitus, Experimental; RGD PMID:26201024 RGD:11079183 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme susceptibility
no_association		 ISO associated with Diabetes Mellitus, Type 2;DNA:snp:exon:g.2350G>A (rs4343) (human)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum (human)
associated with Diabetes Mellitus, Type 2;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)		 RGD PMID:2157294 PMID:7729604 PMID:11106834 PMID:23065222 RGD:7829780 RGD:7829783 RGD:7829794 RGD:8142360 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment ISO associated with Diabetes Mellitus, Experimental
human gene in a mouse model
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:21792177 PMID:31380462 RGD:40818278 RGD:8548900 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G ACP1 acid phosphatase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:12495297 RGD:2313184 NCBI chr2A:257,892...271,320
Ensembl chr2A:253,656...267,086 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing disease_progression ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :g.45T>G (human)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum		 RGD PMID:17970779 PMID:24655058 RGD:8694412 RGD:8694475 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
G ADM adrenomedullin ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:19216096 RGD:2313312 NCBI chr11:10,437,712...10,440,053
Ensembl chr11:10,165,418...10,167,842 		JBrowse link
G ADRB3 adrenoceptor beta 3 ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:9313761 RGD:5684400 NCBI chr 8:37,263,730...37,267,475
Ensembl chr 8:34,441,311...34,443,949 		JBrowse link
G AGER advanced glycosylation end-product specific receptor susceptibility
treatment
severity
no_association		 ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :2245G>A (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation, snp, haplotype:cds, intron:p.G82S, g.1704G>T (human)
associated with Diabetes Mellitus, Experimental
protein:increased expression:retina inner nuclear layer, retinal ganglion cell (rat)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-374T>A (human)
associated with Diabetes Mellitus, Type 1;DNA:SNP:promoter:-374T>A (human)
associated with Diabetes Mellitus, Type 2;DNA:polymorphisms:promoter, cds, intron:g.-443T>C, p.G82S, g.1704G>T (rs1800625, rs2070600, rs184003) (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-429T>C (human)
associated with Diabetes Mellitus, Type 2;DNA:polymorphisms: :p.G82S, 1704G>T, 2184A>G (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-374T>A, - 429T>C (human)		 RGD PMID:11375354 PMID:14704946 PMID:16969646 PMID:19542745 PMID:22116960 More... RGD:7244174 RGD:7244175 RGD:7244176 RGD:7244248 RGD:7244369 RGD:8695958 RGD:8695965 RGD:8695966 RGD:8695967 RGD:8695979 RGD:8695983 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G AGT angiotensinogen treatment ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 1;DNA:polymorphism: :p.M235T (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10862638 PMID:15387897 PMID:21792177 RGD:8548872 RGD:8548900 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16601577 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B no_association
susceptibility		 ISO protein:increased expression:retinal astrocyte (rat)
associated with Diabetes Mellitus, Type 2;DNA:promoter:repeat:g.-2008(AC)n (rs35839483) (human)
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:snp:promoter:g.-106C>T (human)
associated with Diabetes Mellitus;DNA:repeats, snp:promoter:multiple (human)		 RGD PMID:8150024 PMID:16701918 PMID:17003340 PMID:19587357 PMID:21067572 RGD:1626080 RGD:8548640 RGD:8548668 RGD:8548676 RGD:8548684 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO mRNA, protein:increased expression:retina RGD PMID:31759996 RGD:41410819 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G ANG angiogenin ISO associated with Diabetes Mellitus, Type 2;protein:decreased tyrosine phosphorylation:vitreous humor RGD PMID:18978347 RGD:2307061 NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393 		JBrowse link
G ANGPT1 angiopoietin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:12000720 RGD:2313818 NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783 		JBrowse link
G ANGPT2 angiopoietin 2 ISO protein:increased expression:retina (rat) RGD PMID:16520919 RGD:2314216 NCBI chr 8:718,367...782,534
Ensembl chr 8:6,506,014...6,566,915 		JBrowse link
G APOA4 apolipoprotein A4 ISO protein:increased expression:vitreous humor (human) RGD PMID:19081814 RGD:5685692 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382 		JBrowse link
G APOB apolipoprotein B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19448981 RGD:2313976 NCBI chr2A:20,986,464...21,029,004
Ensembl chr2A:21,100,356...21,145,129 		JBrowse link
G APOC3 apolipoprotein C3 severity ISO protein:increased expression:serum RGD PMID:15642486 RGD:2306768 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G APOE apolipoprotein E no_association
susceptibility		 ISO DNA:polymorphism:exon:
associated with Diabetic Mellitus type 2;DNA:polymorphism:exon:		 RGD PMID:11495633 PMID:16862278 RGD:7771553 RGD:7771557 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G APOH apolipoprotein H ISO protein:increased expression:vitreous humor RGD PMID:18695102 RGD:2313982 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483 		JBrowse link
G AQP4 aquaporin 4 ISO RGD PMID:22449442 RGD:8695996 NCBI chr18:20,108,607...20,122,381
Ensembl chr18:23,713,146...23,726,919 		JBrowse link
G ATG7 autophagy related 7 ISO associated with type 1 diabetes mellitus;protein:decreased, altered expression:retina
associated with type 2 diabetes mellitus; protein:decreased, altered expression:retina		 RGD PMID:32272782 RGD:407571700 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398 		JBrowse link
G BDKRB1 bradykinin receptor B1 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:18311190 RGD:2313334 NCBI chr14:76,885,923...76,894,456 JBrowse link
G BDNF brain derived neurotrophic factor ISO associated with Diabetes Mellitus, Experimental;protein:decreased expression:retina: RGD PMID:15331553 RGD:8655657 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239 		JBrowse link
G BECN1 beclin 1 ISO associated with type 2 diabetes mellitus; protein:decreased, altered expression:retina
associated with type 1 diabetes mellitus;protein:decreased, altered expression:retina		 RGD PMID:32272782 RGD:407571700 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G CASP3 caspase 3 ISO CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent
associated with Diabetes Mellitus, Experimental;protein:increased expresssion:retina		 CTD
RGD		 PMID:19013511 PMID:19187597 PMID:20654064 RGD:2311444 RGD:2311448 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CASP9 caspase 9 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased activation:retina RGD PMID:18369072 RGD:2311244 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G CAT catalase ISO protein:decreased expression:retina RGD PMID:21314438 RGD:5130875 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:retina (rat) RGD PMID:23010641 RGD:8548887 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 severity ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased tyrosine phosphorylation:vitreous humor
protein:increased expression:serum		 RGD PMID:16249511 PMID:18978347 RGD:2307061 RGD:2307104 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
G CCN2 cellular communication network factor 2 ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:retina (rat) RGD PMID:19450451 RGD:2314507 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22677420 RGD:8551828 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379 		JBrowse link
G CD34 CD34 molecule ISO mRNA, protein:increased expression:retina RGD PMID:31759996 RGD:41410819 NCBI chr 1:183,459,028...183,489,583
Ensembl chr 1:188,272,551...188,297,384 		JBrowse link
G CD59 CD59 molecule (CD59 blood group) ISO protein:decreased expression:retina RGD PMID:12453906 RGD:1600487 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157 		JBrowse link
G CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 disease_progression ISO DNA:SNP:intron: (rs7756992) (human) RGD PMID:28821857 RGD:401850599 NCBI chr 6:20,357,897...21,064,873
Ensembl chr 6:20,717,011...21,405,566 		JBrowse link
G CFB complement factor B no_association ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs1048709 (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs537160, rs4151657, rs2072633 (human)		 RGD PMID:23864767 RGD:7365019 NCBI chr 6:31,606,716...31,612,782 JBrowse link
G CFH complement factor H ISO associated with Diabetes Mellitus, Type 2; DNA:SNP: :rs800292(human)
associated with Diabetes Mellitus, Type 1;DNA:SNP: :rs1410996(human) 		RGD PMID:23296223 PMID:23864767 RGD:7365019 RGD:7365023 NCBI chr 1:172,155,882...172,251,632
Ensembl chr 1:176,455,247...176,525,521 		JBrowse link
G CLDN1 claudin 1 treatment ISO RGD PMID:25685822 RGD:11341734 NCBI chr 3:187,328,629...187,345,360
Ensembl chr 3:195,882,239...195,899,248 		JBrowse link
G CLU clusterin treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:19875648 RGD:9068395 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G CRP C-reactive protein ISO protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20012460 RGD:8547537 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO RGD PMID:17194635 RGD:2311361 NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 severity ISO protein:increased expression:vitreous humor RGD PMID:15630447 RGD:2306559 NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 severity ISO mRNA,protein:increased expression:retina: RGD PMID:30787185 PMID:34362349 RGD:155663348 RGD:155663356 NCBI chr15:19,871,584...19,881,817
Ensembl chr15:38,121,574...38,129,471 		JBrowse link
G EDN1 endothelin 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:increased secretion:plasma
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:exon:p.K198N (human)
mRNA:increased expression:retina (rat)		 RGD PMID:18806884 PMID:19293263 PMID:20628425 RGD:2313279 RGD:2313281 RGD:9068929 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545 		JBrowse link
G EGFR epidermal growth factor receptor treatment ISO associated with Diabetes Mellitus, Experimental
protein:increased expression:retina		 RGD PMID:7947554 PMID:23831329 RGD:10059675 RGD:1580957 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615 		JBrowse link
G ELN elastin ISO RGD PMID:11707314 RGD:9585734
G ENG endoglin ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:plasma,vitreous body RGD PMID:16202216 RGD:1580961 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641 		JBrowse link
G EP300 E1A binding protein p300 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21885871 RGD:7349382 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G EPO erythropoietin susceptibility ISO associated with Diabetes Mellitus, Experimental
protein:increased expression:serum,vitreous body
DNA:snp:promoter:-1125T>G(rs1617640)(human)		 RGD PMID:18235022 PMID:18458324 PMID:18670462 PMID:24508793 RGD:10400906 RGD:2313837 RGD:2313838 RGD:2313890 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO protein:increased expression:optic choroid vascular plexus: RGD PMID:11375345 RGD:8693344 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased expression:aqueous humor,serum RGD PMID:12417540 RGD:2313865 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased activity:plasma (human) RGD PMID:10837382 RGD:2312398 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO DNA:polymorphism:intron:g.754C>G(human)
associated with Pregnancy in Diabetics
associated with Diabetes Mellitus, Experimental
DNA:polymorphism:promotor:g.-553T>A(human)		 RGD PMID:9141532 PMID:14975211 PMID:17997184 PMID:18279437 RGD:2315844 RGD:2315845 RGD:2315875 RGD:2315885 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 treatment ISO RGD PMID:17143550 PMID:18174522 RGD:10402119 RGD:2313721 NCBI chr13:9,584,850...9,779,542 JBrowse link
G FUCA1 alpha-L-fucosidase 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased activity:retina RGD PMID:10353622 RGD:2315932 NCBI chr 1:23,039,126...23,060,514
Ensembl chr 1:24,022,967...24,043,850 		JBrowse link
G GAD2 glutamate decarboxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21412422 NCBI chr10:26,392,877...26,481,859
Ensembl chr10:26,759,243...26,843,197 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO associated with Diabetes Mellitus, Experimental RGD PMID:18852331 RGD:2315975 NCBI chr12:6,665,218...6,669,170
Ensembl chr12:6,583,895...6,587,729 		JBrowse link
G GC GC vitamin D binding protein ISO protein:increased expression:vitreous body RGD PMID:16080911 RGD:2315548 NCBI chr 4:52,431,196...52,473,762
Ensembl chr 4:58,729,236...58,792,073 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus,Insulin-Dependent;protein:increased activity:serum RGD PMID:11311965 RGD:2315614 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GLO1 glyoxalase I ISO DNA:SNP:promoter:-7C>T (human) RGD PMID:21738003 RGD:7242569 NCBI chr 6:38,247,881...38,275,098
Ensembl chr 6:39,434,746...39,461,971 		JBrowse link
G GLUL glutamate-ammonia ligase treatment ISO associated with Experimental Diabetes Mellitus RGD PMID:34133251 RGD:401794594 NCBI chr 1:157,882,258...157,891,562
Ensembl chr 1:161,534,106...161,543,411 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility ISO associated with Diabetes Mellitus, Type 1;DNA:deletion:cds (human) RGD PMID:19752172 RGD:7495818 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G HES1 hes family bHLH transcription factor 1 ISO mRNA:increased expression:retina: RGD PMID:30787185 RGD:155663348 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 ISO mRNA:increased expression:retina: RGD PMID:30787185 RGD:155663348 NCBI chr 6:123,527,180...123,538,794
Ensembl chr 6:127,647,547...127,659,056 		JBrowse link
G HFE homeostatic iron regulator ISO associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:15347835 RGD:8694362 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G HGF hepatocyte growth factor disease_progression ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum RGD PMID:15525877 PMID:18335393 RGD:2313565 RGD:8548539 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment
severity		 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:retina (rat)
protein:increased expression:retina, vascular endothelial cell (human)		 RGD PMID:17229797 PMID:20515763 PMID:22110070 RGD:7364887 RGD:8694462 RGD:8696025 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO RGD PMID:14988264 RGD:1358731 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.K469E (human)		 CTD
RGD		 PMID:10485912 PMID:18834676 PMID:18942221 PMID:25066112 RGD:11354984 RGD:2313471 RGD:2313472 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605 		JBrowse link
G IGF1 insulin like growth factor 1 susceptibility ISO protein:decreased expression:serum RGD PMID:16873705 PMID:17194636 RGD:1598424 RGD:2313764 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGF1R insulin like growth factor 1 receptor disease_progression ISO mRNA:increased expression:retina: RGD PMID:12781065 RGD:10046008 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G IL10 interleukin 10 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased tyrosine phosphorylation:vitreous humor		 RGD PMID:16696964 PMID:18978347 PMID:18988929 PMID:22105495 RGD:1598486 RGD:2307061 RGD:2307272 RGD:7364856 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371 		JBrowse link
G IL18 interleukin 18 ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:serum RGD PMID:16260350 PMID:19011009 RGD:4889417 RGD:8655907 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371 		JBrowse link
G IL1A interleukin 1 alpha ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased tyrosine phosphorylation:vitreous humor RGD PMID:18978347 RGD:2307061 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801 		JBrowse link
G IL1B interleukin 1 beta ISO associated with Diabetes Mellitus, Type 2; protein:decreased tyrosine phosphorylation:vitreous humor
protein:increased expression:serum, vitreous humour		 RGD PMID:16284605 PMID:18978347 RGD:2307061 RGD:7401212 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL6 interleukin 6 susceptibility ISO associated with Diabetes Mellitus, Type1;DNA:polymorphism:promoter:-174G>C(human)
associated with Diabetes Mellitus; DNA:polymorphism:promoter:-174G>C (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
associated with Diabetes Mellitus, Typpe 1;protein:increased expression:serum:		 RGD PMID:17725274 PMID:18988929 PMID:19140096 PMID:19542902 RGD:2307267 RGD:2307272 RGD:7829749 RGD:7829816 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G INS insulin ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22046295 PMID:30463601 RGD:6902909 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G INSR insulin receptor ISO MouseDO NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889 		JBrowse link
G ITGA2 integrin subunit alpha 2 no_association
susceptibility
severity		 ISO associated with Diabetes Mellitus, Type 2;DNA:snp:cds:c.807T>C (human)
associated with Diabetes Mellitus, Type 2;DNA:snp:intron:IVS7+3160A>G (human)
associated with Diabetes Mellitus; DNA:transition:cds:807C>T (human)
associated with Diabetes Mellitus, Type 2;DNA:snp:intron:IVS8-1059T>C (human)		 RGD PMID:12540964 PMID:18806884 PMID:21632096 PMID:23776381 RGD:2307419 RGD:2313281 RGD:7777103 RGD:8686431 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720 		JBrowse link
G ITGA4 integrin subunit alpha 4 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:19553613 RGD:9698417 NCBI chr2B:68,719,376...68,802,488
Ensembl chr2B:186,530,187...186,612,203 		JBrowse link
G ITGAM integrin subunit alpha M ISO mRNA, protein:increased expression:retina (rat) RGD PMID:33614447 RGD:329901937 NCBI chr16:23,634,476...23,707,147
Ensembl chr16:31,630,146...31,702,406 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO protein:increased expression:optic choroid vascular plexus: RGD PMID:11375345 RGD:8693344 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO mRNA,protein:increased expression:retina: RGD PMID:30787185 RGD:155663348 NCBI chr20:10,582,234...10,618,507
Ensembl chr20:10,582,094...10,618,383 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:21672350 PMID:22143324 RGD:8662869 RGD:8662907 NCBI chr 1:135,391,321...135,424,100 JBrowse link
G KDM1A lysine demethylase 1A ISO mRNA:increased expression:retina (human)
mRNA, protein:increased expression:retina (rat)		 RGD PMID:23423566 RGD:8547881 NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:retina RGD PMID:23633659 RGD:10412733 NCBI chr19:10,037,544...10,055,091
Ensembl chr19:10,701,303...10,717,604 		JBrowse link
G LOC100971425 somatotropin ISO RGD PMID:3183302 RGD:2315688 NCBI chr17:58,010,848...58,013,421
Ensembl chr17:63,103,332...63,105,067 		JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain susceptibility
severity		 ISO associated with Diabetes Mellitus, Type 1;DNA:polymorphisms, haplotypes:cds:HLA-DQB1*0201, HLA-DQB1*0501, HLA-DQB1*0504 (human)
DNA:polymorphisms, haplotype:cds:HLA-DQB1*0201, HLA-DQB1*0302 (human)		 RGD PMID:8932997 PMID:19551681 RGD:7421552 RGD:7483573 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272 		JBrowse link
G LOC100982859 class I histocompatibility antigen, Gogo-B*0101 alpha chain susceptibility ISO associated with Diabetes Mellitus, Type 1; DNA:polymorphisms:cds:HLA-B*49 (human) RGD PMID:22981956 RGD:7365095 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067 		JBrowse link
G LOC100986914 cytochrome b-245 light chain ISO associated with Diabetes Mellitus, Experimental RGD PMID:19685553 RGD:2317854 NCBI chr16:69,356,396...69,364,225
Ensembl chr16:89,016,349...89,024,719 		JBrowse link
G LTA lymphotoxin alpha no_association
susceptibility		 ISO associated with Diabetes Mellitus, Type 2;DNA:polymorphism:intron, exon:252A>G, 804C>A (human) RGD PMID:11399938 PMID:16979413 RGD:8548772 RGD:8548797 NCBI chr 6:31,233,411...31,235,409
Ensembl chr 6:32,123,353...32,125,375 		JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 ISO associated with type 2 diabetes mellitus;DNA:increased expression:plasma (human) RGD PMID:33221518 RGD:242905212 NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210 		JBrowse link
G MFN2 mitofusin 2 ISO associated with Diabetes Mellitus, Experimental;mRNA, protein:decreased expression:retina (rat) RGD PMID:28487236 RGD:12910715 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased expression:plasma RGD PMID:12714657 PMID:18552985 RGD:1582582 RGD:8547849 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279 		JBrowse link
G MMP9 matrix metallopeptidase 9 disease_progression ISO associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2		 RGD PMID:10374894 PMID:16643893 PMID:21933988 RGD:1582616 RGD:8547815 RGD:8547857 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility ISO associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human) RGD PMID:9040583 RGD:6893525 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419 		JBrowse link
G MYSM1 Myb like, SWIRM and MPN domains 1 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:snps:introns: IVS1-1269C>T, IVS6+1700G>A (rs2811893, rs12092121) (human) RGD PMID:21310492 RGD:9589162 NCBI chr 1:57,916,267...57,961,812
Ensembl chr 1:59,626,793...59,666,809 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO associated with Diabetes Mellitus, Experimental;protein:decreased activity:retina RGD PMID:23633659 RGD:10412733 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085 		JBrowse link
G NGF nerve growth factor ISO protein:increased expression:serum
associated with Experimental Diabetes Mellitus		 RGD PMID:18282491 PMID:24030532 RGD:405100241 RGD:7242804 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NOS1 nitric oxide synthase 1 ISO mRNA, protein:decreased expression:retina RGD PMID:17545029 RGD:1642141 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005 		JBrowse link
G NOS3 nitric oxide synthase 3 no_association
severity
treatment
susceptibility
onset		 ISO associated with Diabetes Mellitus, Type 2;DNA:duplication:intron:IVS4?-?+27 (human)
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:snps, duplication, haplotype:promoter, cds, intron:g.-786T>C, p.E298N, IVS4?-?+27 (human)
associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:retina (rat)
associated with Diabetes Mellitus, Type 1;DNA:duplication:intron:IVS4?-?+27 (human)
associated with Diabetes Mellitus, Type 2;DNA:snp:exon:c.894G>T (human)
DNA:snps:promoter, exon:c.-786T>C, c.774C>T (human)		 RGD PMID:11918626 PMID:15890549 PMID:16581274 PMID:17558849 PMID:17973941 More... RGD:7421531 RGD:7421532 RGD:7421533 RGD:7771565 RGD:7771568 RGD:7771569 RGD:7771606 RGD:7775042 RGD:7777101 RGD:7777103 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233 		JBrowse link
G NOTCH1 notch receptor 1 treatment ISO RGD PMID:30787185 RGD:155663348 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G NPPA natriuretic peptide A ISO protein:increased expression:vitreous humor RGD PMID:15273657 RGD:2313589 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G NPR3 natriuretic peptide receptor 3 ISO mRNA:decreased expression:retina (rat) RGD PMID:15789000 RGD:1580773 NCBI chr 5:77,542,200...77,621,983
Ensembl chr 5:82,926,409...83,004,964 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO associated with Experimental Diabetes Mellitus;protein:altered expression:retina RGD PMID:37904673 RGD:408364965 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269 		JBrowse link
G NRP1 neuropilin 1 treatment ISO RGD PMID:26554379 RGD:401901170 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G NUTF2 nuclear transport factor 2 treatment ISO mRNA:decreased expression:peripheral blood: RGD PMID:19404486 RGD:9831377 NCBI chr16:48,188,533...48,214,205
Ensembl chr16:67,575,842...67,601,053 		JBrowse link
G OCLN occludin treatment ISO RGD PMID:25685822 RGD:11341734 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342 		JBrowse link
G PF4 platelet factor 4 ISO protein:increased expression:retina RGD PMID:23352833 RGD:329901846 NCBI chr 4:50,208,806...50,210,570
Ensembl chr 4:56,041,833...56,043,750 		JBrowse link
G PGF placental growth factor ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21408222 RGD:6483775 NCBI chr14:55,494,152...55,508,066
Ensembl chr14:74,338,976...74,352,964 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO mRNA, protein:increased expression:retina RGD PMID:31759996 RGD:41410819 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614 		JBrowse link
G PLK4 polo like kinase 4 treatment ISO RGD PMID:33416109 RGD:401850543 NCBI chr 4:120,044,423...120,062,544
Ensembl chr 4:131,349,562...131,371,054 		JBrowse link
G PON1 paraoxonase 1 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
DNA:polymorphism:promoter:g.-907C>G (human)
associated with Diabetes Mellitus;DNA:missense mutation:cds:p.L55M (rs854560) (human)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;protein:decreased activity:serum (human)		 RGD
CTD		 PMID:9661650 PMID:15270786 PMID:16949520 PMID:20012460 PMID:24100645 RGD:2313272 RGD:8547537 RGD:8547548 RGD:8547572 NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO Retinal Leukostasis;associated with Diabetes Mellitus, Experimental RGD PMID:17003451 RGD:8552824 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:retina (rat) RGD PMID:20566666 PMID:22003111 RGD:5686899 RGD:6484532 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212 		JBrowse link
G PTEN phosphatase and tensin homolog ISO mRNA, protein:decreased expression:retina RGD PMID:31759996 RGD:41410819 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G RBP4 retinol binding protein 4 severity ISO protein:increased expression:blood plasma (human) RGD PMID:30135138 RGD:329849110 NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887 		JBrowse link
G RETN resistin ISO associated with Diabetes Mellitus, Type 2 RGD PMID:17303077 RGD:7207162 NCBI chr19:6,958,536...6,960,032
Ensembl chr19:7,812,942...7,814,909 		JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO mRNA,protein:increased expression:retina RGD PMID:28973045 RGD:243048421 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308 		JBrowse link
G SERPINA4 serpin family A member 4 ISO protein:decreased expression:vitreous fluid (human) RGD PMID:8950506 RGD:1580289 NCBI chr14:75,185,501...75,194,061
Ensembl chr14:94,517,341...94,525,820 		JBrowse link
G SERPINE1 serpin family E member 1 susceptibility
no_association		 ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:plasma (human)
associated with Diabetes Mellitus, Type 2;DNA:deletion:promoter:g.-676_-674delG (human)
associated with Diabetes Mellitus, Type 2;DNA:snp, deletion:promoter:g.-844G>A, g.-676_-674delG (human)
associated with Diabetes Mellitus;repeat, snp:intron, 3' utr:g.7844(CA)1-6, ? (human)		 RGD PMID:7974340 PMID:9201602 PMID:12660488 PMID:19419896 PMID:23281898 RGD:8547697 RGD:8547699 RGD:8547710 RGD:8547740 RGD:8547741 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
G SERPINF1 serpin family F member 1 severity ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:vitreous humor
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNPs:promoter:g.-5740T>C, g.-5308G>A (rs12150053, rs12948385) (human)
protein:alternative form:vitreous humor
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:retina
associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum		 RGD PMID:15059706 PMID:16054135 PMID:17658465 PMID:18025835 PMID:18455830 More... RGD:1580135 RGD:2312337 RGD:2312341 RGD:2312344 RGD:2312346 RGD:2312348 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568 		JBrowse link
G SGF29 SAGA complex associated factor 29 severity ISO associated with Diabetes Mellitus, Type 1; DNA:SNP:intron: rs10521145(human) RGD PMID:21441570 RGD:9587455 Ensembl chr16:29,030,587...29,068,795 JBrowse link
G SIRT1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894401 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G SLIT2 slit guidance ligand 2 ISO mRNA,protein:increased expression:retina RGD PMID:28973045 RGD:243048421 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656 		JBrowse link
G SOD1 superoxide dismutase 1 ISO human gene in a mouse model
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:19074809 RGD:8655572 NCBI chr21:18,029,831...18,037,526 JBrowse link
G SOD3 superoxide dismutase 3 ISO RGD PMID:12663605 RGD:1581298 NCBI chr 4:19,195,941...19,201,298
Ensembl chr 4:24,485,059...24,485,781 		JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 treatment ISO associated with type 2 diabetes mellitus RGD PMID:30096827 RGD:155631301 NCBI chr15:53,117,891...53,150,790
Ensembl chr15:72,741,482...72,770,876 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO ClinVar Annotator: match by term: Diabetic retinopathy ClinVar PMID:9536098 PMID:15731757 PMID:16799921 PMID:17576681 PMID:21270064 More... NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856 		JBrowse link
G THBS1 thrombospondin 1 ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17117553 RGD:2317943 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
G TIMM44 translocase of inner mitochondrial membrane 44 ISO associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:retina RGD PMID:22003103 RGD:13463597 NCBI chr19:7,227,965...7,245,045
Ensembl chr19:8,081,069...8,100,479 		JBrowse link
G TLR4 toll like receptor 4 onset ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.N299G (human) RGD PMID:19135114 RGD:2312487 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNF tumor necrosis factor no_association
disease_progression		 ISO associated with Diabetes Mellitus, Type 2;DNA:polymorphism:promoter:-302A>G (human)
protein:increased expression:serum, vitreous humour
associated with Diabetes Mellitus, Type 1;protein:increased expression:platelet:		 RGD PMID:10540181 PMID:16284605 PMID:16979413 PMID:22105495 RGD:7364856 RGD:7394805 RGD:7401212 RGD:8548772 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G UTS2 urotensin 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:18338983 RGD:2306795 NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:vitreous humor, serum RGD PMID:19237221 RGD:2312762 NCBI chr 1:103,377,815...103,395,118
Ensembl chr 1:102,091,336...102,107,732 		JBrowse link
G VDR vitamin D receptor ISO RGD PMID:15899948 RGD:1580363 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:retina
associated with Diabetes Mellitus, type 2; protein:increased expression:aqueous humor of eyeball:		 CTD
RGD		 PMID:9852717 PMID:11978667 PMID:15788408 PMID:16636650 PMID:17513698 More... RGD:1580565 RGD:2301992 RGD:41410819 RGD:8547996 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
G VPS26A VPS26 retromer complex component A susceptibility ISO DNA:SNP:: (rs1802295) (Human) RGD PMID:28821857 RGD:401850599 NCBI chr10:65,591,415...65,639,894
Ensembl chr10:68,125,409...68,173,317 		JBrowse link
G VTN vitronectin ISO associated with Diabetes Mellitus, Experimental RGD PMID:7536680 PMID:8804356 RGD:10040982 RGD:1580818 NCBI chr17:28,403,813...28,407,202
Ensembl chr17:28,906,508...28,909,583 		JBrowse link
G VWF von Willebrand factor ISO RGD PMID:10077454 RGD:1580648 NCBI chr12:6,073,836...6,249,806
Ensembl chr12:5,990,612...6,165,153 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein susceptibility ISO DNA:SNP:: (rs10010131) (Human) RGD PMID:28821857 RGD:401850599 Ensembl chr 4:6,345,864...6,379,287 JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:SNP:cd: p.R399Q G>A (rs25487) (human) RGD PMID:30472145 RGD:401827275 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520 		JBrowse link
Fetal Macrosomia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF4A hepatocyte nuclear factor 4 alpha ISO DNA:mutations: : RGD PMID:17407387 PMID:19435144 RGD:12904698 RGD:12904767 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:increased expression:serum: RGD PMID:17113804 RGD:12743591 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO protein:increased expression:serum: RGD PMID:17113804 RGD:12743591 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G LIPC lipase C, hepatic type ISO associated with Diabetes Mellitus, Experimental; protein:increased expression:liver (rat) RGD PMID:10600655 RGD:2308786 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005 		JBrowse link
Mauriac Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHKG2 phosphorylase kinase catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Mauriac syndrome ClinVar PMID:27207549 PMID:28492532 NCBI chr16:24,211,929...24,221,756
Ensembl chr16:31,115,033...31,127,216 		JBrowse link
Perlman syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPI alkaline phosphatase, intestinal ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,687,673...119,692,300
Ensembl chr2B:238,606,722...238,611,350 		JBrowse link
G ARMC9 armadillo repeat containing 9 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,454,310...118,644,303
Ensembl chr2B:237,243,120...237,412,620 		JBrowse link
G ATG16L1 autophagy related 16 like 1 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:120,479,534...120,523,563
Ensembl chr2B:239,392,990...239,436,766 		JBrowse link
G B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,644,899...118,650,463 JBrowse link
G C13H2orf72 chromosome 13 C2orf72 homolog ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,293,626...118,306,034 JBrowse link
G CAB39 calcium binding protein 39 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:117,965,688...118,074,063
Ensembl chr2B:236,809,549...236,870,646 		JBrowse link
G CHRND cholinergic receptor nicotinic delta subunit ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,757,722...119,768,254
Ensembl chr2B:238,676,495...238,686,987 		JBrowse link
G CHRNG cholinergic receptor nicotinic gamma subunit ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,770,636...119,779,332
Ensembl chr2B:238,689,935...238,696,526 		JBrowse link
G COPS7B COP9 signalosome subunit 7B ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,033,879...119,061,293
Ensembl chr2B:237,821,398...237,849,340 		JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO ClinVar Annotator: match by term: Predisposition to Wilms tumor ClinVar PMID:9536098 PMID:17576681 PMID:25099282 PMID:28492532 NCBI chr11:10,884,353...10,913,246
Ensembl chr11:10,610,892...10,639,808 		JBrowse link
G DGKD diacylglycerol kinase delta ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:120,582,278...120,701,165
Ensembl chr2B:239,525,401...239,611,873 		JBrowse link
G DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:25741868 NCBI chr13:53,982,914...54,011,076
Ensembl chr13:72,760,610...72,787,325 		JBrowse link
G DIS3L2 DIS3 like 3'-5' exoribonuclease 2 ISO ClinVar Annotator: match by term: Perlman syndrome OMIM
ClinVar		 PMID:6093533 PMID:9536098 PMID:10508986 PMID:16199547 PMID:16957732 More... NCBI chr2B:119,187,659...119,558,347
Ensembl chr2B:238,030,931...238,347,570 		JBrowse link
G EFHD1 EF-hand domain family member D1 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,865,065...119,914,446 JBrowse link
G EIF4E2 eukaryotic translation initiation factor 4E family member 2 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,782,057...119,814,992
Ensembl chr2B:238,700,790...238,733,654 		JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,929,004...120,090,367
Ensembl chr2B:238,847,674...239,007,549 		JBrowse link
G GPR55 G protein-coupled receptor 55 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,159,511...118,163,334
Ensembl chr2B:236,958,210...236,959,169 		JBrowse link
G HJURP Holliday junction recognition protein ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:121,076,314...121,096,783
Ensembl chr2B:239,950,984...239,967,955 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,362,719...118,381,253
Ensembl chr2B:237,153,709...237,170,591 		JBrowse link
G ITM2C integral membrane protein 2C ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,116,228...118,131,379 JBrowse link
G KCNJ13 potassium inwardly rectifying channel subfamily J member 13 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,997,643...120,009,927
Ensembl chr2B:238,916,083...238,926,178 		JBrowse link
G LOC100991867 alkaline phosphatase, placental type ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,594,655...119,600,138
Ensembl chr2B:238,383,768...238,388,105 		JBrowse link
G LOC100993088 endothelin-converting enzyme-like 1 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,711,355...119,719,378
Ensembl chr2B:238,630,731...238,637,233 		JBrowse link
G MROH2A maestro heat like repeat family member 2A ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:121,034,266...121,074,112 JBrowse link
G NCL nucleolin ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,703,148...118,712,893
Ensembl chr2B:237,490,378...237,500,193 		JBrowse link
G NEU2 neuraminidase 2 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:120,260,420...120,262,930
Ensembl chr2B:239,174,532...239,176,917 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:120,110,441...120,153,934
Ensembl chr2B:239,027,286...239,155,874 		JBrowse link
G NMUR1 neuromedin U receptor 1 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,773,713...118,854,590
Ensembl chr2B:237,556,920...237,564,268 		JBrowse link
G NPPC natriuretic peptide C ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,148,774...119,153,381
Ensembl chr2B:237,936,939...237,941,244 		JBrowse link
G PDE6D phosphodiesterase 6D ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,984,666...119,033,525
Ensembl chr2B:237,772,529...237,821,044 		JBrowse link
G PRSS56 serine protease 56 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,751,950...119,757,308
Ensembl chr2B:238,670,931...238,675,839 		JBrowse link
G PSMD1 proteasome 26S subunit, non-ATPase 1 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,313,158...118,428,636
Ensembl chr2B:237,102,623...237,215,322 		JBrowse link
G PTMA prothymosin alpha ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,959,382...118,964,364 JBrowse link
G SAG S-antigen visual arrestin ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:120,532,049...120,574,914
Ensembl chr2B:239,449,910...239,487,537 		JBrowse link
G SNORC secondary ossification center associated regulator of chondrocyte maturation ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:120,100,778...120,110,444 JBrowse link
G SP100 SP100 nuclear antigen ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:117,673,152...117,799,911
Ensembl chr2B:236,496,446...236,601,096 		JBrowse link
G SP110 SP110 nuclear body protein ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:117,417,230...117,472,246
Ensembl chr2B:236,221,833...236,275,562 		JBrowse link
G SP140 SP140 nuclear body protein ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:117,477,923...117,565,367
Ensembl chr2B:236,279,460...236,366,314 		JBrowse link
G SP140L SP140 nuclear body protein like ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:117,578,707...117,663,997
Ensembl chr2B:236,380,818...236,461,871 		JBrowse link
G SPATA3 spermatogenesis associated 3 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,246,905...118,265,322
Ensembl chr2B:237,042,156...237,053,441 		JBrowse link
G SPP2 secreted phosphoprotein 2 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:121,294,427...121,320,831
Ensembl chr2B:240,165,495...240,191,869 		JBrowse link
G TEX44 testis expressed 44 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:118,843,674...118,845,087
Ensembl chr2B:237,627,967...237,629,154 		JBrowse link
G TIGD1 tigger transposable element derived 1 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:119,779,452...119,782,065
Ensembl chr2B:238,698,311...238,700,086 		JBrowse link
G TRPM8 transient receptor potential cation channel subfamily M member 8 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:121,160,045...121,261,645
Ensembl chr2B:240,039,104...240,130,524 		JBrowse link
G USP40 ubiquitin specific peptidase 40 ISO ClinVar Annotator: match by term: Perlman syndrome ClinVar PMID:28492532 NCBI chr2B:120,704,893...120,796,084
Ensembl chr2B:239,617,442...239,705,721 		JBrowse link
proliferative diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:aqueous humor RGD PMID:22563689 RGD:8694466 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:increased expression:vitreous humor RGD PMID:16364297 RGD:8695978 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G BCOR BCL6 corepressor susceptibility ISO associated with type 1 diabetes mellitus;DNA:hypomethylation:5'UTR RGD PMID:26248552 RGD:155631276 NCBI chr  X:32,497,931...32,624,307
Ensembl chr  X:40,202,235...40,249,986 		JBrowse link
G CALD1 caldesmon 1 ISO mRNA:increased expression:retina (human) RGD PMID:35692390 RGD:401851065 NCBI chr 7:126,743,466...126,935,412
Ensembl chr 7:139,337,692...139,440,643 		JBrowse link
G CALU calumenin ISO mRNA:increased expression:retina (human) RGD PMID:35692390 RGD:401851065 NCBI chr 7:120,691,092...120,723,303
Ensembl chr 7:133,223,269...133,247,167 		JBrowse link
G CAT catalase ISO associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum: RGD PMID:24092995 RGD:9068931 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 disease_progression ISO associated with Diabetes Mellitus, Type 2;DNA:polymorphism:promoter:g.-2518A>G (human)
associated with Diabetes Mellitus;protein:increased expression:vitreous humor (human)		 RGD PMID:21850157 PMID:23549806 RGD:8548851 RGD:8549477 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384 		JBrowse link
G CCN1 cellular communication network factor 1 ISO protein:increased expression:vitreous body (human) RGD PMID:22160564 RGD:329845551 NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147 		JBrowse link
G COL5A2 collagen type V alpha 2 chain ISO mRNA:increased expression:retina (human) RGD PMID:35692390 RGD:401851065 NCBI chr2B:76,339,756...76,487,133
Ensembl chr2B:194,259,316...194,407,237 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain ISO mRNA:increased expression:retina (human) RGD PMID:35692390 RGD:401851065 NCBI chr2B:124,554,478...124,644,482 JBrowse link
G CORO1C coronin 1C ISO mRNA:increased expression:retina (human) RGD PMID:35692390 RGD:401851065 NCBI chr12:106,220,755...106,306,098
Ensembl chr12:109,617,093...109,674,368 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 disease_progression ISO protein:decreased expression:vitreous: RGD PMID:22864860 RGD:9685437 NCBI chr 8:116,248,587...116,364,966
Ensembl chr 8:118,998,530...119,114,273 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO protein:increased expression:vitreous: RGD PMID:22868384 RGD:10402118 NCBI chr13:9,584,850...9,779,542 JBrowse link
G IL6R interleukin 6 receptor ISO protein:increased expression:serum RGD PMID:17401618 RGD:10402814 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 ISO protein:increased activity:serum: RGD PMID:28724746 RGD:151356966 NCBI chr10:30,579,220...30,607,249
Ensembl chr10:30,933,483...30,960,824 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein:increased expression:vitreous: RGD PMID:19799585 RGD:10449447 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma onset
susceptibility		 ISO DNA:snp:cds:p.P12A (rs1801282) (human)
associated with Diabetes Mellitus, Type 2;DNA:snp:promoter:c.-2819A>G (human)		 RGD PMID:18541841 PMID:19125195 PMID:23559865 RGD:2301854 RGD:8552820 RGD:8699508 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO protein:increased expression:vitreous humor (human) RGD PMID:33627831 RGD:401976389 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421 		JBrowse link
G RBP4 retinol binding protein 4 disease_progression ISO protein:increased expression:blood serum (human) RGD PMID:20233518 RGD:329853306 NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887 		JBrowse link
G SERPINE1 serpin family E member 1 susceptibility
disease_progression		 ISO associated with Diabetes Mellitus, Type 2;DNA:deletion:promoter:g.-676_-674delG (human)
protein:increased expression:plasma (human)		 RGD PMID:16416371 PMID:23304115 RGD:8699494 RGD:8699497 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO protein:increased expression:vitreous fluid (human) RGD PMID:11723044 PMID:15059706 RGD:1580135 RGD:8554895 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568 		JBrowse link
G SLIT2 slit guidance ligand 2 ISO associated with eye disease; protein:increased expression:vitreous RGD PMID:28973045 RGD:243048421 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656 		JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 ISO DNA:snp:exon:p.P281P (rs2235611) (human) RGD PMID:21309690 RGD:11039452 NCBI chr20:39,795,659...39,801,864
Ensembl chr20:40,888,560...40,891,853 		JBrowse link
G TIMM44 translocase of inner mitochondrial membrane 44 ISO mRNA:decreased expression:retina RGD PMID:22003103 RGD:13463597 NCBI chr19:7,227,965...7,245,045
Ensembl chr19:8,081,069...8,100,479 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO associated with Diabetes Mellitus, Type 2; protein:increased expression:retina RGD PMID:16054135 RGD:2312348 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
severe nonproliferative diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRB platelet derived growth factor receptor beta ISO MouseDO NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15809
    disease of anatomical entity 15486
      endocrine system disease 6228
        diabetes mellitus 1345
          Diabetes Complications 490
            Achard-Thiers Syndrome 0
            Diabetic Bone Disease 0
            Diabetic Cardiomyopathies 55
            Diabetic Coma + 0
            Diabetic Cystopathy 2
            Diabetic Embryopathy 1
            Diabetic Nephropathies 285
            Fetal Macrosomia + 50
            Mauriac Syndrome 1
            diabetic angiopathy + 188
            diabetic cataract 1
            diabetic encephalopathy 8
            diabetic ketoacidosis 5
            diabetic neuropathy + 72
Path 2
Term Annotations click to browse term
  disease 15809
    Developmental Disease 13814
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 12862
        genetic disease 12557
          inherited metabolic disorder 5926
            carbohydrate metabolic disorder 2828
              glucose metabolism disease 1573
                diabetes mellitus 1345
                  Diabetes Complications 490
                    Achard-Thiers Syndrome 0
                    Diabetic Bone Disease 0
                    Diabetic Cardiomyopathies 55
                    Diabetic Coma + 0
                    Diabetic Cystopathy 2
                    Diabetic Embryopathy 1
                    Diabetic Nephropathies 285
                    Fetal Macrosomia + 50
                    Mauriac Syndrome 1
                    diabetic angiopathy + 188
                    diabetic cataract 1
                    diabetic encephalopathy 8
                    diabetic ketoacidosis 5
                    diabetic neuropathy + 72
paths to the root