ACE2 (angiotensin I converting enzyme 2) - Rat Genome Database
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Gene: ACE2 (angiotensin I converting enzyme 2) Pan paniscus
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Symbol: ACE2
Name: angiotensin I converting enzyme 2
RGD ID: 11765567
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); metallocarboxypeptidase activity (ortholog); metallopeptidase activity (ortholog); INVOLVED IN angiotensin-mediated drinking behavior (ortholog); maternal process involved in female pregnancy (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN angiotensin (1-7) signaling pathway; renin-angiotensin cascade pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Lung Injury (ortholog); adult respiratory distress syndrome (ortholog); FOUND IN apical plasma membrane (ortholog); brush border membrane (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X15,470,896 - 15,510,891 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX15,470,896 - 15,510,891 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X8,189,267 - 8,229,415 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
ACE2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X15,470,896 - 15,510,891 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX15,470,896 - 15,510,891 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X8,189,267 - 8,229,415 (-)NCBIMhudiblu_PPA_v0panPan3
ACE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX15,561,033 - 15,602,148 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 EnsemblX15,494,566 - 15,607,236 (-)EnsemblGRCh38hg38GRCh38
GRCh38X15,518,197 - 15,602,158 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,579,156 - 15,620,192 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,489,077 - 15,529,058 (-)NCBINCBI36hg18NCBI36
Build 34X15,338,812 - 15,378,794NCBI
CeleraX19,694,648 - 19,735,682 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,333,989 - 13,374,656 (-)NCBIHuRef
CHM1_1X15,610,102 - 15,651,154 (-)NCBICHM1_1
Ace2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X162,922,338 - 162,971,414 (+)NCBIGRCm39mm39
GRCm38X164,139,342 - 164,188,418 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX164,139,332 - 164,188,420 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X160,577,274 - 160,626,350 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X159,484,737 - 159,532,523 (+)NCBImm8
CeleraX147,353,722 - 147,402,904 (+)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX76.12NCBI
Ace2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X32,050,734 - 32,095,860 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX32,049,931 - 32,096,016 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X32,422,286 - 32,469,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X51,051,758 - 51,096,036 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X51,105,228 - 51,149,505 (-)NCBI
CeleraX30,638,123 - 30,683,403 (-)NCBICelera
Cytogenetic MapXq14NCBI
Ace2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555192,591,248 - 2,633,495 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555192,591,229 - 2,643,705 (+)NCBIChiLan1.0ChiLan1.0
ACE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX11,798,839 - 11,900,594 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X11,798,839 - 11,839,591 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ace2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364704,964,526 - 5,011,808 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACE2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX12,099,853 - 12,151,275 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X12,099,849 - 12,152,204 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X13,061,317 - 13,089,851 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACE2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X14,032,231 - 14,094,163 (-)NCBI
ChlSab1.1 EnsemblX14,030,233 - 14,077,785 (-)Ensembl
Ace2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624829344,823 - 391,451 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000052700   ⟹   ENSPPAP00000029848
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX15,470,896 - 15,510,891 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052701   ⟹   ENSPPAP00000029849
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX15,470,896 - 15,510,842 (-)Ensembl
RefSeq Acc Id: XM_008974180   ⟹   XP_008972428
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X15,470,896 - 15,510,891 (-)NCBI
Mhudiblu_PPA_v0X8,189,402 - 8,229,415 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008974189   ⟹   XP_008972437
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X15,470,896 - 15,510,858 (-)NCBI
Mhudiblu_PPA_v0X8,189,267 - 8,229,352 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008972428 (Get FASTA)   NCBI Sequence Viewer  
  XP_008972437 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008972428   ⟸   XM_008974180
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008972437   ⟸   XM_008974189
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000029849   ⟸   ENSPPAT00000052701
RefSeq Acc Id: ENSPPAP00000029848   ⟸   ENSPPAT00000052700
Protein Domains
Collectrin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037947 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000029848 UniProtKB/TrEMBL
  ENSPPAP00000029849 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052700 UniProtKB/TrEMBL
  ENSPPAT00000052701 UniProtKB/TrEMBL
InterPro Collectrin_dom UniProtKB/TrEMBL
  Peptidase_M2 UniProtKB/TrEMBL
KEGG Report pps:100970340 UniProtKB/TrEMBL
NCBI Gene ACE2 ENTREZGENE
PANTHER PTHR10514 UniProtKB/TrEMBL
Pfam Collectrin UniProtKB/TrEMBL
  Peptidase_M2 UniProtKB/TrEMBL
PRINTS PEPDIPTASEA UniProtKB/TrEMBL
UniProt A0A2R9BJK0_PANPA UniProtKB/TrEMBL
  A0A2R9BKD8_PANPA UniProtKB/TrEMBL