GSTM1 (glutathione S-transferase mu 1) - Rat Genome Database

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Gene: GSTM1 (glutathione S-transferase mu 1) Pan paniscus
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Symbol: GSTM1
Name: glutathione S-transferase mu 1
RGD ID: 11739414
Description: ENCODES a protein that exhibits enzyme binding (ortholog); glutathione binding (ortholog); glutathione transferase activity (ortholog); INVOLVED IN aging (ortholog); cellular detoxification of nitrogen compound (ortholog); cellular response to xenobiotic stimulus (ortholog); PARTICIPATES IN cyclophosphamide pharmacodynamics pathway; cyclophosphamide pharmacokinetics pathway; glutathione conjugation pathway; ASSOCIATED WITH acute chest syndrome (ortholog); acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC100992725
RGD Orthologs
Human
Mouse
Rat
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11128,003,736 - 128,009,696 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1127,979,238 - 128,010,411 (-)Ensemblpanpan1.1panPan2


Disease Annotations     Click to see Annotation Detail View
acute chest syndrome  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
aggressive periodontitis  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic disease  (ISO)
amphetamine abuse  (ISO)
angle-closure glaucoma  (ISO)
aplastic anemia  (ISO)
asbestosis  (ISO)
asphyxia neonatorum  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
autistic disorder  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Bronchopulmonary Dysplasia  (ISO)
cataract  (ISO)
cervical cancer  (ISO)
cervix carcinoma  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chloracne  (ISO)
cholangiocarcinoma  (ISO)
cholestasis  (ISO)
Chromosome Aberrations  (ISO)
Chromosome Breakage  (ISO)
Chronic Bronchitis  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Periodontitis  (ISO)
colorectal adenocarcinoma  (ISO)
colorectal adenoma  (ISO)
colorectal cancer  (ISO)
colorectal carcinoma  (ISO)
Colorectal Neoplasms  (ISO)
Congenital Abnormalities  (ISO)
congenital heart disease  (ISO)
coronary artery disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
cystic fibrosis  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diffuse large B-cell lymphoma  (ISO)
Disease Susceptibility  (ISO)
drug allergy  (ISO)
Drug-induced Anemia  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
end stage renal disease  (ISO)
erythema nodosum  (ISO)
esophageal atresia  (ISO)
esophageal cancer  (ISO)
esophagus adenocarcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
exfoliation syndrome  (ISO)
Experimental Liver Cirrhosis  (ISO)
Fanconi anemia  (ISO)
Female Infertility  (ISO)
Femur Head Necrosis  (ISO)
Fetal Growth Retardation  (ISO)
gallbladder cancer  (ISO)
gastritis  (ISO)
Genetic Predisposition to Disease  (ISO)
Graft vs Host Disease  (ISO)
head and neck cancer  (ISO)
Hearing Loss, Noise-Induced  (ISO)
Hematologic Neoplasms  (ISO)
hepatic veno-occlusive disease  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Hirschsprung's disease  (ISO)
Hodgkin's lymphoma  (ISO)
hypertension  (ISO)
Hypertension Resistant to Conventional Therapy  (ISO)
hypospadias  (ISO)
Hypotension  (ISO)
infectious mononucleosis  (ISO)
inflammatory bowel disease  (ISO)
Iron Overload  (ISO)
keratosis  (ISO)
Kidney Neoplasms  (ISO)
Kuhnt-Junius degeneration  (ISO)
larynx cancer  (ISO)
leukemia  (ISO)
leukopenia  (ISO)
Leukoplakia  (ISO)
liver cirrhosis  (ISO)
Liver Neoplasms  (ISO)
Liver Reperfusion Injury  (ISO)
lung cancer  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lymphoid leukemia  (ISO)
Lynch syndrome  (ISO)
macular degeneration  (ISO)
malignant astrocytoma  (ISO)
malignant mesothelioma  (ISO)
medulloblastoma  (ISO)
Mesothelioma  (ISO)
Metabolic Syndrome  (ISO)
methemoglobinemia  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
Mouth Abnormalities  (ISO)
movement disease  (ISO)
multiple myeloma  (ISO)
multiple sclerosis  (ISO)
myelodysplastic syndrome  (ISO)
myeloid leukemia  (ISO)
Nasal Polyps  (ISO)
nasopharynx carcinoma  (ISO)
Neoplasms, Second Primary  (ISO)
neurodegenerative disease  (ISO)
non-alcoholic fatty liver disease  (ISO)
optic neuritis  (ISO)
oral cavity cancer  (ISO)
oral mucosa leukoplakia  (ISO)
oral squamous cell carcinoma  (ISO)
oral submucous fibrosis  (ISO)
orofacial cleft  (ISO)
ovary epithelial cancer  (ISO)
papillomavirus infectious disease  (ISO)
Parkinson's disease  (ISO)
periodontitis  (ISO)
polycythemia vera  (ISO)
porphyria cutanea tarda  (ISO)
pre-malignant neoplasm  (ISO)
Premature Birth  (ISO)
Presbycusis  (ISO)
primary open angle glaucoma  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pterygium  (ISO)
pulmonary emphysema  (ISO)
pulmonary tuberculosis  (ISO)
Raynaud disease  (ISO)
renal cell carcinoma  (ISO)
rheumatoid arthritis  (ISO)
schizophrenia  (ISO)
senile cataract  (ISO)
Sjögren-Mikulicz Syndrome  (ISO)
skin disease  (ISO)
skin melanoma  (ISO)
small intestine adenocarcinoma  (ISO)
squamous cell carcinoma  (ISO)
Stevens-Johnson syndrome  (ISO)
stomach cancer  (ISO)
Stroke  (ISO)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
Temporomandibular Joint Disorders  (ISO)
Testicular Neoplasms  (ISO)
thalassemia  (ISO)
toxic encephalopathy  (ISO)
transitional cell carcinoma  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
Ulcer  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
urticaria  (ISO)
Vaso-occlusive Crisis  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
GSTM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11128,003,736 - 128,009,696 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1127,979,238 - 128,010,411 (-)Ensemblpanpan1.1panPan2
GSTM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1109,687,814 - 109,709,039 (+)EnsemblGRCh38hg38GRCh38
GRCh381109,687,817 - 109,693,745 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371110,230,439 - 110,236,367 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,031,965 - 110,037,890 (+)NCBINCBI36hg18NCBI36
Build 341109,942,483 - 109,948,409NCBI
Cytogenetic Map1p13.3NCBI
Gstm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393107,919,566 - 107,925,289 (-)NCBIGRCm39mm39
GRCm39 Ensembl3107,919,571 - 107,925,289 (-)Ensembl
GRCm383108,012,250 - 108,017,973 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,012,255 - 108,017,973 (-)EnsemblGRCm38mm10GRCm38
MGSCv373107,815,168 - 107,820,891 (-)NCBIGRCm37mm9NCBIm37
MGSCv363108,140,314 - 108,146,029 (-)NCBImm8
Celera3110,345,820 - 110,351,544 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
Gstm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22195,649,845 - 195,655,402 (-)NCBI
Rnor_6.0 Ensembl2210,803,869 - 210,809,306 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02210,803,869 - 210,809,461 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02230,272,740 - 230,278,278 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,575,444 - 203,580,821 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12203,538,197 - 203,543,575 (-)NCBI
Celera2188,295,244 - 188,300,621 (-)NCBICelera
Cytogenetic Map2q34NCBI
LOC103224275
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12023,854,969 - 23,861,634 (-)NCBI
Vero_WHO_p1.0NW_023670255134 - 1,611 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001367588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003810642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000044707   ⟹   ENSPPAP00000021902
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1127,979,238 - 127,985,268 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044720   ⟹   ENSPPAP00000021916
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1127,980,082 - 127,985,197 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044735   ⟹   ENSPPAP00000021931
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1127,982,550 - 128,009,650 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044781   ⟹   ENSPPAP00000021976
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,003,736 - 128,010,411 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044799   ⟹   ENSPPAP00000021994
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,004,195 - 128,009,618 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044802   ⟹   ENSPPAP00000021997
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,004,195 - 128,009,618 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044806   ⟹   ENSPPAP00000022002
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,004,195 - 128,009,618 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044813   ⟹   ENSPPAP00000022008
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1128,008,184 - 128,009,618 (-)Ensembl
RefSeq Acc Id: XM_003810642   ⟹   XP_003810690
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11128,003,736 - 128,009,696 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001354517 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003810690   ⟸   XM_003810642
- Sequence:
RefSeq Acc Id: ENSPPAP00000021902   ⟸   ENSPPAT00000044707
RefSeq Acc Id: ENSPPAP00000021976   ⟸   ENSPPAT00000044781
RefSeq Acc Id: ENSPPAP00000021994   ⟸   ENSPPAT00000044799
RefSeq Acc Id: ENSPPAP00000021916   ⟸   ENSPPAT00000044720
RefSeq Acc Id: ENSPPAP00000021931   ⟸   ENSPPAT00000044735
RefSeq Acc Id: ENSPPAP00000021997   ⟸   ENSPPAT00000044802
RefSeq Acc Id: ENSPPAP00000022002   ⟸   ENSPPAT00000044806
RefSeq Acc Id: ENSPPAP00000022008   ⟸   ENSPPAT00000044813


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034147 Ensembl, ENTREZGENE
NCBI Gene LOC100992725 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-18 GSTM1  glutathione S-transferase mu 1  LOC100992725  glutathione S-transferase Mu 1  Symbol and/or name change 5135510 APPROVED