LOC100986914 (cytochrome b-245 light chain) - Rat Genome Database

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Gene: LOC100986914 (cytochrome b-245 light chain) Pan paniscus
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Symbol: LOC100986914 (Ensembl: CYBA)
Name: cytochrome b-245 light chain
RGD ID: 11778387
Description: ENCODES a protein that exhibits electron transfer activity (ortholog); protein heterodimerization activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to angiotensin (ortholog); cellular response to gamma radiation (ortholog); PARTICIPATES IN thyroid hormone biosynthetic pathway; ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); acute lymphoblastic leukemia (ortholog); asthma (ortholog); FOUND IN apical plasma membrane (ortholog); dendrite (ortholog); focal adhesion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,416,331 - 98,424,174 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,328,442 - 104,336,271 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,356,396 - 69,364,225 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,016,349 - 89,024,719 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,016,349 - 89,024,719 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to amino acid stimulus  (ISO)
cellular response to angiotensin  (ISO)
cellular response to gamma radiation  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to L-glutamine  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to tumor necrosis factor  (ISO)
cytochrome complex assembly  (ISO)
establishment of localization in cell  (IEA,ISO)
hydrogen peroxide biosynthetic process  (ISO)
inflammatory response  (ISO)
innate immune response  (IEA)
mucus secretion  (IEA,ISO)
negative regulation of glomerular filtration by angiotensin  (ISO)
positive regulation of blood pressure  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of defense response to bacterium  (ISO)
positive regulation of endothelial cell proliferation  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of mucus secretion  (IEA,ISO)
positive regulation of NAD(P)H oxidase activity  (ISO)
positive regulation of oxygen metabolic process  (ISO)
positive regulation of phagocytosis  (ISO)
positive regulation of reactive oxygen species biosynthetic process  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of superoxide anion generation  (ISO)
positive regulation of toll-like receptor 2 signaling pathway  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
reactive oxygen species metabolic process  (IEA,ISO)
regulation of release of sequestered calcium ion into cytosol  (IEA,ISO)
respiratory burst  (ISO)
response to activity  (ISO)
response to aldosterone  (ISO)
response to hypoxia  (ISO)
response to interleukin-1  (ISO)
response to nutrient levels  (ISO)
response to xenobiotic stimulus  (ISO)
smooth muscle hypertrophy  (ISO)
superoxide anion generation  (ISO)
superoxide metabolic process  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100986914
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,416,331 - 98,424,174 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,328,442 - 104,336,271 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,356,396 - 69,364,225 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,016,349 - 89,024,719 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,016,349 - 89,024,719 (-)Ensemblpanpan1.1panPan2
CYBA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,643,289 - 88,651,053 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,643,275 - 88,651,083 (-)EnsemblGRCh38hg38GRCh38
GRCh371688,709,697 - 88,717,461 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,237,198 - 87,244,958 (-)NCBINCBI36Build 36hg18NCBI36
Build 341687,237,198 - 87,244,950NCBI
Celera1673,779,369 - 73,787,129 (-)NCBICelera
Cytogenetic Map16q24.2NCBI
HuRef1674,403,728 - 74,411,523 (-)NCBIHuRef
CHM1_11690,120,999 - 90,128,842 (-)NCBICHM1_1
T2T-CHM13v2.01694,711,169 - 94,718,983 (-)NCBIT2T-CHM13v2.0
Cyba
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,151,510 - 123,159,679 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,151,515 - 123,159,669 (-)EnsemblGRCm39 Ensembl
GRCm388122,424,771 - 122,432,940 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,424,776 - 122,432,930 (-)EnsemblGRCm38mm10GRCm38
MGSCv378124,948,671 - 124,956,840 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,310,866 - 125,319,017 (-)NCBIMGSCv36mm8
Celera8126,653,882 - 126,662,049 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.04NCBI
Cyba
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,396,143 - 67,404,214 (-)NCBIGRCr8
mRatBN7.21950,487,598 - 50,495,669 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,487,597 - 50,495,721 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,282,778 - 57,290,847 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,962,531 - 57,970,602 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,181,396 - 60,189,465 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,249,634 - 55,257,824 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,249,616 - 55,257,876 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01965,959,818 - 65,967,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,713,150 - 52,721,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11952,718,030 - 52,726,490 (-)NCBI
Celera1949,727,142 - 49,735,154 (-)NCBICelera
Cytogenetic Map19q12NCBI
LOC102004641
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,569,727 - 2,574,118 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,570,843 - 2,573,822 (-)NCBIChiLan1.0ChiLan1.0
CYBA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,692,865 - 64,701,056 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,692,123 - 64,704,893 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,703,545 - 64,711,735 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,912,202 - 64,920,393 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,911,577 - 64,920,464 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,938,335 - 64,946,503 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,770,091 - 64,778,279 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,176,122 - 65,184,313 (+)NCBIUU_Cfam_GSD_1.0
LOC101967032
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,283,408 - 25,291,407 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366411,036,967 - 1,044,991 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366411,036,967 - 1,044,954 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYBA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,015,162 - 1,021,420 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,015,212 - 1,021,422 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103233451
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,023,134 - 74,030,793 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,023,082 - 74,030,750 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660471,654,155 - 1,661,751 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101717043
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746911,842 - 919,362 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746911,852 - 919,361 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003805759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000018677   ⟹   ENSPPAP00000004027
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1689,016,349 - 89,024,719 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000018694   ⟹   ENSPPAP00000004033
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1689,018,222 - 89,024,648 (-)Ensembl
RefSeq Acc Id: XM_003805759   ⟹   XP_003805807
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21898,416,331 - 98,424,174 (-)NCBI
NHGRI_mPanPan116104,328,442 - 104,336,271 (-)NCBI
Mhudiblu_PPA_v01669,356,396 - 69,364,225 (-)NCBI
PanPan1.11689,016,349 - 89,024,719 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003805807 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000004027
  ENSPPAP00000004027.1
  ENSPPAP00000004033.1
RefSeq Acc Id: XP_003805807   ⟸   XM_003805759
- UniProtKB: A0A2R8ZJK5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000004027   ⟸   ENSPPAT00000018677
Ensembl Acc Id: ENSPPAP00000004033   ⟸   ENSPPAT00000018694


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000017054 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000018677.1 UniProtKB/TrEMBL
  ENSPPAT00000018694.1 UniProtKB/TrEMBL
InterPro Cyt_b558_asu UniProtKB/TrEMBL
KEGG Report pps:100986914 UniProtKB/TrEMBL
NCBI Gene LOC100986914 ENTREZGENE
PANTHER CYTOCHROME B-245 LIGHT CHAIN UniProtKB/TrEMBL
  PTHR15168 UniProtKB/TrEMBL
Pfam Cytochrom_B558a UniProtKB/TrEMBL
PIRSF Cytochr_b558a UniProtKB/TrEMBL
UniProt A0A2R8ZJK5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZMM7_PANPA UniProtKB/TrEMBL