ADIPOQ (adiponectin, C1Q and collagen domain containing) - Rat Genome Database

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Gene: ADIPOQ (adiponectin, C1Q and collagen domain containing) Pan paniscus
Analyze
Symbol: ADIPOQ
Name: adiponectin, C1Q and collagen domain containing
RGD ID: 11864848
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); cellular response to cAMP (ortholog); cellular response to epinephrine stimulus (ortholog); PARTICIPATES IN adiponectin signaling pathway; ASSOCIATED WITH 3MC syndrome 1 (ortholog); Acute Lung Injury (ortholog); Alcoholic Fatty Liver (ortholog); FOUND IN extracellular space (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adiponectin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13192,341,471 - 192,354,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,341,320 - 192,354,885 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03183,876,051 - 183,889,723 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
3MC syndrome 1  (ISO)
Acute Lung Injury  (ISO)
Alcoholic Fatty Liver  (ISO)
Alzheimer's disease  (ISO)
amyloidosis  (ISO)
ankylosing spondylitis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
autoimmune hepatitis  (ISO)
Behcet's disease  (ISO)
biliary atresia  (ISO)
bipolar disorder  (ISO)
brain infarction  (ISO)
breast cancer  (ISO)
cardiomyopathy  (ISO)
cardiovascular system disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
Cognitive Dysfunction  (ISO)
colitis  (ISO)
congestive heart failure  (ISO)
coronary aneurysm  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
coronary restenosis  (ISO)
Crohn's disease  (ISO)
dementia  (ISO)
diabetes mellitus  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diffuse scleroderma  (ISO)
dry eye syndrome  (ISO)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
familial hyperlipidemia  (ISO)
familial Mediterranean fever  (ISO)
fatty liver disease  (ISO)
Fetal Growth Retardation  (ISO)
gestational diabetes  (ISO)
Graft vs Host Disease  (ISO)
Graves' disease  (ISO)
hepatocellular carcinoma  (ISO)
heroin dependence  (ISO)
HIV-Associated Lipodystrophy Syndrome  (ISO)
Human Viral Hepatitis  (ISO)
Huntington's disease  (ISO)
Hyperemia  (ISO)
hyperglycemia  (ISO)
hyperinsulinism  (ISO)
hypertension  (ISO)
hyperthyroidism  (ISO)
Hypertriglyceridemia  (ISO)
Hypoadiponectinemia  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
Insulin Resistance  (ISO)
Jaundice  (ISO)
Kawasaki disease  (ISO)
Kidney Reperfusion Injury  (ISO)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (ISO)
Mammary Neoplasms, Experimental  (ISO)
Masked Hypertension  (ISO)
Metabolic Syndrome  (ISO)
multiple sclerosis  (ISO)
Mycobacterium avium complex disease  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
myocarditis  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
Oxygen-Induced Retinopathy  (ISO)
Perennial Allergic Rhinitis  (ISO)
peripheral artery disease  (ISO)
polycystic ovary syndrome  (ISO)
primary open angle glaucoma  (ISO)
proliferative diabetic retinopathy  (ISO)
prostate adenocarcinoma  (ISO)
pulmonary edema  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Rett syndrome  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (ISO)
sleep apnea  (ISO)
Spinal Cord Injuries  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (ISO)
tongue squamous cell carcinoma  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
vascular disease  (ISO)
visual epilepsy  (ISO)
Weight Gain  (ISO)
Weight Loss  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
brown fat cell differentiation  (IEA,ISO)
cellular response to cAMP  (ISO)
cellular response to epinephrine stimulus  (ISO)
cellular response to insulin stimulus  (IEA,ISO)
cellular response to xenobiotic stimulus  (IEA)
circadian rhythm  (ISO)
detection of oxidative stress  (IEA)
fatty acid beta-oxidation  (IEA,ISO)
fatty acid oxidation  (IEA,ISO)
gene expression  (IEA,ISO)
glucose homeostasis  (IEA,ISO)
glucose metabolic process  (IEA,ISO)
low-density lipoprotein particle clearance  (IEA)
negative regulation of blood pressure  (IEA)
negative regulation of cell migration  (IEA)
negative regulation of cold-induced thermogenesis  (IEA)
negative regulation of DNA biosynthetic process  (IEA)
negative regulation of DNA-templated transcription  (IEA)
negative regulation of ERK1 and ERK2 cascade  (IEA)
negative regulation of fat cell differentiation  (IEA)
negative regulation of gluconeogenesis  (IEA,ISO)
negative regulation of granulocyte differentiation  (IEA)
negative regulation of heterotypic cell-cell adhesion  (IEA)
negative regulation of hormone secretion  (ISO)
negative regulation of I-kappaB kinase/NF-kappaB signaling  (IEA)
negative regulation of inflammatory response  (IEA)
negative regulation of intracellular protein transport  (IEA)
negative regulation of low-density lipoprotein receptor activity  (IEA,ISO)
negative regulation of macrophage derived foam cell differentiation  (IEA)
negative regulation of macrophage differentiation  (IEA)
negative regulation of MAP kinase activity  (IEA)
negative regulation of metanephric mesenchymal cell migration  (IEA)
negative regulation of phagocytosis  (IEA)
negative regulation of platelet-derived growth factor receptor signaling pathway  (IEA)
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway  (IEA)
negative regulation of protein autophosphorylation  (IEA)
negative regulation of receptor binding  (IEA)
negative regulation of synaptic transmission  (IEA)
negative regulation of tumor necrosis factor production  (IEA)
negative regulation of tumor necrosis factor-mediated signaling pathway  (IEA)
negative regulation of vascular associated smooth muscle cell migration  (IEA)
negative regulation of vascular associated smooth muscle cell proliferation  (IEA)
positive regulation of cAMP-dependent protein kinase activity  (IEA)
positive regulation of cholesterol efflux  (IEA)
positive regulation of cold-induced thermogenesis  (IEA)
positive regulation of fatty acid metabolic process  (IEA,ISO)
positive regulation of glucose import  (IEA,ISO)
positive regulation of glycogen (starch) synthase activity  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IEA,ISO)
positive regulation of interleukin-8 production  (IEA)
positive regulation of lipid transporter activity  (IEA)
positive regulation of metanephric podocyte development  (IEA)
positive regulation of monocyte chemotactic protein-1 production  (IEA)
positive regulation of myeloid cell apoptotic process  (IEA)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of protein kinase A signaling  (IEA)
positive regulation of protein kinase activity  (ISO)
positive regulation of protein phosphorylation  (IEA)
positive regulation of renal albumin absorption  (IEA)
positive regulation of signal transduction  (IEA,ISO)
protein localization to plasma membrane  (IEA)
regulation of glucose metabolic process  (IEA)
response to activity  (ISO)
response to bacterium  (IEA,ISO)
response to ethanol  (ISO)
response to glucocorticoid  (ISO)
response to glucose  (IEA,ISO)
response to hypoxia  (ISO)
response to linoleic acid  (ISO)
response to nutrient  (ISO)
response to nutrient levels  (ISO)
response to sucrose  (ISO)
response to tumor necrosis factor  (IEA)
response to xenobiotic stimulus  (ISO)
signal transduction  (IEA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
ADIPOQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13192,341,471 - 192,354,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,341,320 - 192,354,885 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03183,876,051 - 183,889,723 (+)NCBIMhudiblu_PPA_v0panPan3
ADIPOQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,842,710 - 186,858,463 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3186,842,704 - 186,858,463 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,560,499 - 186,576,252 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363188,043,157 - 188,058,946 (+)NCBINCBI36hg18NCBI36
Build 343188,043,164 - 188,058,952NCBI
Celera3184,996,682 - 185,012,474 (+)NCBI
Cytogenetic Map3q27.3NCBI
HuRef3183,969,546 - 183,985,186 (+)NCBIHuRef
CHM1_13186,523,992 - 186,539,778 (+)NCBICHM1_1
T2T-CHM13v2.03189,664,780 - 189,680,531 (+)NCBI
Adipoq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,965,286 - 22,976,718 (+)NCBIGRCm39mm39
GRCm39 Ensembl1622,965,286 - 22,976,778 (+)Ensembl
GRCm381623,146,536 - 23,157,968 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,146,536 - 23,158,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv371623,146,609 - 23,158,041 (+)NCBIGRCm37mm9NCBIm37
MGSCv361623,061,870 - 23,073,302 (+)NCBImm8
Celera1623,704,853 - 23,716,285 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.96NCBI
Adipoq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21177,721,912 - 77,735,644 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1177,721,912 - 77,735,564 (-)Ensembl
Rnor_6.01181,330,845 - 81,344,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,330,293 - 81,344,488 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01184,363,940 - 84,382,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,908,291 - 79,911,065 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11179,965,888 - 79,968,654 (-)NCBI
Celera1176,596,543 - 76,599,824 (-)NCBICelera
Cytogenetic Map11q23NCBI
Adipoq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542020,912,348 - 20,914,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542020,911,181 - 20,922,992 (-)NCBIChiLan1.0ChiLan1.0
ADIPOQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,398,310 - 19,410,519 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,354,825 - 19,409,844 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,492,088 - 23,493,907 (+)NCBI
ROS_Cfam_1.03419,309,590 - 19,321,861 (+)NCBI
ROS_Cfam_1.0 Ensembl3419,309,535 - 19,321,387 (+)Ensembl
UMICH_Zoey_3.13419,349,075 - 19,350,894 (+)NCBI
UNSW_CanFamBas_1.03419,348,981 - 19,350,799 (+)NCBI
UU_Cfam_GSD_1.03419,582,218 - 19,584,037 (+)NCBI
Adipoq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,076,470 - 117,087,548 (-)NCBI
SpeTri2.0NW_0049365783,168,599 - 3,179,369 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADIPOQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,633,685 - 124,646,646 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,633,906 - 124,646,237 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213134,076,753 - 134,077,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADIPOQ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,128,427 - 81,142,779 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1581,129,795 - 81,147,391 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604154,621,772 - 54,634,568 (+)NCBIVero_WHO_p1.0
Adipoq
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473069,941,001 - 69,957,012 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473069,941,963 - 69,959,266 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000064992   ⟹   ENSPPAP00000042063
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3192,341,320 - 192,354,885 (+)Ensembl
RefSeq Acc Id: XM_003806634   ⟹   XP_003806682
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.13192,341,471 - 192,354,885 (+)NCBI
Mhudiblu_PPA_v03183,876,051 - 183,889,723 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003806635   ⟹   XP_003806683
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.13192,341,485 - 192,353,651 (+)NCBI
Mhudiblu_PPA_v03183,876,065 - 183,888,226 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034955624   ⟹   XP_034811515
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v03183,886,150 - 183,888,226 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003806682 (Get FASTA)   NCBI Sequence Viewer  
  XP_003806683 (Get FASTA)   NCBI Sequence Viewer  
  XP_034811515 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003806682   ⟸   XM_003806634
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003806683   ⟸   XM_003806635
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_034811515   ⟸   XM_034955624
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000042063   ⟸   ENSPPAT00000064992
Protein Domains
C1q


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043624 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000042063.1 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064992.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.40 UniProtKB/TrEMBL
InterPro Adiponectin UniProtKB/TrEMBL
  C1q_dom UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/TrEMBL
NCBI Gene ADIPOQ ENTREZGENE
PANTHER PTHR15427:SF20 UniProtKB/TrEMBL
Pfam C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
PRINTS COMPLEMNTC1Q UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/TrEMBL
SMART C1Q UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/TrEMBL
UniProt A0A2R9CM19_PANPA UniProtKB/TrEMBL