TGFBI (transforming growth factor beta induced) - Rat Genome Database

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Gene: TGFBI (transforming growth factor beta induced) Pan paniscus
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Symbol: TGFBI
Name: transforming growth factor beta induced
RGD ID: 11796738
Description: ENCODES a protein that exhibits cell adhesion molecule binding (inferred); collagen binding (inferred); extracellular matrix binding (inferred); INVOLVED IN cell adhesion (ortholog); chondrocyte differentiation (ortholog); extracellular matrix organization (ortholog); ASSOCIATED WITH corneal dystrophy (ortholog); Diabetic Nephropathies (ortholog); epithelial basement membrane dystrophy (ortholog); FOUND IN basement membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC117980386; transforming growth factor-beta-induced protein ig-h3; uncharacterized LOC117980386
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24131,295,568 - 131,350,946 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15129,405,032 - 129,490,506 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05131,420,403 - 131,455,265 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15137,560,046 - 137,594,970 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5137,559,321 - 137,596,392 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TGFBI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24131,295,568 - 131,350,946 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15129,405,032 - 129,490,506 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05131,420,403 - 131,455,265 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15137,560,046 - 137,594,970 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5137,559,321 - 137,596,392 (+)Ensemblpanpan1.1panPan2
TGFBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385136,028,988 - 136,063,818 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5136,028,988 - 136,063,818 (+)EnsemblGRCh38hg38GRCh38
GRCh375135,364,677 - 135,399,507 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365135,392,597 - 135,427,406 (+)NCBINCBI36Build 36hg18NCBI36
Build 345135,392,596 - 135,427,406NCBI
Celera5131,489,316 - 131,524,237 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5130,553,034 - 130,587,955 (+)NCBIHuRef
CHM1_15134,797,217 - 134,832,140 (+)NCBICHM1_1
T2T-CHM13v2.05136,551,486 - 136,586,315 (+)NCBIT2T-CHM13v2.0
Tgfbi
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391356,757,399 - 56,787,172 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1356,757,336 - 56,787,375 (+)EnsemblGRCm39 Ensembl
GRCm381356,609,586 - 56,639,359 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1356,609,523 - 56,639,562 (+)EnsemblGRCm38mm10GRCm38
MGSCv371356,710,964 - 56,740,700 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361356,619,225 - 56,648,961 (+)NCBIMGSCv36mm8
Celera1357,674,398 - 57,704,061 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.09NCBI
Tgfbi
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8177,960,885 - 7,990,234 (-)NCBIGRCr8
mRatBN7.2177,955,603 - 7,984,903 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,955,603 - 7,985,240 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx177,973,969 - 8,002,492 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0179,505,209 - 9,534,325 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0177,970,355 - 7,998,883 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,400,123 - 8,429,338 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,400,146 - 8,429,338 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01710,576,347 - 10,605,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41713,904,882 - 13,935,110 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11713,907,546 - 13,912,997 (-)NCBI
Celera178,049,686 - 8,078,886 (-)NCBICelera
Cytogenetic Map17p14NCBI
Tgfbi
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540831,093,050 - 31,125,398 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540831,093,450 - 31,124,715 (+)NCBIChiLan1.0ChiLan1.0
TGFBI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11123,932,038 - 23,971,983 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1123,938,453 - 23,971,607 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1122,686,607 - 22,719,238 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01124,755,795 - 24,788,452 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1124,755,189 - 24,788,074 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11123,442,552 - 23,475,191 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01123,309,379 - 23,341,990 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01123,958,407 - 23,991,029 (+)NCBIUU_Cfam_GSD_1.0
Tgfbi
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213124,103,129 - 124,136,978 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365973,127,795 - 3,162,242 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365973,128,007 - 3,161,885 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGFBI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2138,191,807 - 138,225,366 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12138,191,793 - 138,225,373 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22143,856,237 - 143,880,047 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TGFBI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12338,774,387 - 38,808,624 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2338,774,473 - 38,808,649 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603439,100,477 - 39,134,819 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tgfbi
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473311,038,043 - 11,071,175 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473311,038,041 - 11,070,559 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000046875   ⟹   ENSPPAP00000024050
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5137,559,321 - 137,596,392 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000046887   ⟹   ENSPPAP00000024062
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5137,559,321 - 137,596,392 (+)Ensembl
RefSeq Acc Id: XM_003829252   ⟹   XP_003829300
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24131,315,955 - 131,350,946 (+)NCBI
NHGRI_mPanPan15129,455,614 - 129,490,506 (+)NCBI
Mhudiblu_PPA_v05131,420,403 - 131,455,265 (+)NCBI
PanPan1.15137,560,046 - 137,594,970 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055112711   ⟹   XP_054968686
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24131,295,568 - 131,350,946 (+)NCBI
NHGRI_mPanPan15129,405,032 - 129,490,506 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003829300 (Get FASTA)   NCBI Sequence Viewer  
  XP_054968686 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024050.1
  ENSPPAP00000024062
  ENSPPAP00000024062.1
RefSeq Acc Id: XP_003829300   ⟸   XM_003829252
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B390 (UniProtKB/TrEMBL),   A0A2R9B745 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000024050   ⟸   ENSPPAT00000046875
Ensembl Acc Id: ENSPPAP00000024062   ⟸   ENSPPAT00000046887
RefSeq Acc Id: XP_054968686   ⟸   XM_055112711
- Peptide Label: isoform X2
Protein Domains
EMI   FAS1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035154 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046875.1 UniProtKB/TrEMBL
  ENSPPAT00000046887.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.180.10 UniProtKB/TrEMBL
InterPro Adhesion/Biosynth-related UniProtKB/TrEMBL
  EMI_domain UniProtKB/TrEMBL
  FAS1_dom_sf UniProtKB/TrEMBL
  FAS1_domain UniProtKB/TrEMBL
  TGFBI/POSTN UniProtKB/TrEMBL
KEGG Report pps:100971542 UniProtKB/TrEMBL
NCBI Gene TGFBI ENTREZGENE
PANTHER PERIOSTIN-RELATED UniProtKB/TrEMBL
  PTHR10900:SF82 UniProtKB/TrEMBL
Pfam Fasciclin UniProtKB/TrEMBL
PIRSF BIGH3_OSF2 UniProtKB/TrEMBL
PROSITE EMI UniProtKB/TrEMBL
  FAS1 UniProtKB/TrEMBL
SMART FAS1 UniProtKB/TrEMBL
Superfamily-SCOP SSF82153 UniProtKB/TrEMBL
UniProt A0A2R9B390 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B745 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 TGFBI  transforming growth factor beta induced  LOC117980386  uncharacterized LOC117980386  Data merged from RGD:32726547 737654 PROVISIONAL