ATP5F1B (ATP synthase F1 subunit beta)

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Gene: ATP5F1B (ATP synthase F1 subunit beta) Pan paniscus

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Symbol:

ATP5F1B

Name:

ATP synthase F1 subunit beta

RGD ID:

11707015

Description:

ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to interleukin-7 (ortholog); cellular response to peptide (ortholog); cold acclimation (ortholog); PARTICIPATES IN electron transport chain pathway; ASSOCIATED WITH acute kidney failure (ortholog); cardiomyopathy (ortholog); cataract 15 multiple types (ortholog); FOUND IN cell surface (ortholog); membrane raft (ortholog); mitochondrial inner membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ATP synthase subunit beta, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; ATP5B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	37,680,429 - 37,689,113 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	37,677,947 - 37,685,879 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	32,264,570 - 32,272,419 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	32,519,749 - 32,527,753 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	32,519,749 - 32,527,753 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

cardiomyopathy (ISO)

cataract 15 multiple types (ISO)

Charcot-Marie-Tooth disease axonal type 2U (ISO)

COVID-19 (ISO)

Diabetic Nephropathies (ISO)

Experimental Diabetes Mellitus (ISO)

Fetal Growth Retardation (ISO)

Hypermetabolism due to Defect in Mitochondria (ISO)

HYPERMETABOLISM DUE TO UNCOUPLED MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION 2 (ISO)

Hypoxia (ISO)

INTERSTITIAL LUNG AND LIVER DISEASE (ISO)

Liver Injury (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

obesity (ISO)

paraplegia (ISO)

polycystic ovary syndrome (ISO)

pre-malignant neoplasm (ISO)

spinocerebellar ataxia type 17 (ISO)

transient cerebral ischemia (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

ATP biosynthetic process (IEA)

cellular response to interleukin-7 (IEA,ISO)

cellular response to peptide (ISO)

cold acclimation (ISO)

lipid metabolic process (IEA,ISO)

liver development (ISO)

negative regulation of cell adhesion involved in substrate-bound cell migration (IEA,ISO)

positive regulation of blood vessel endothelial cell migration (IEA)

proton motive force-driven ATP synthesis (IEA)

proton motive force-driven mitochondrial ATP synthesis (IEA)

proton transmembrane transport (IEA)

receptor-mediated endocytosis (ISO)

regulation of intracellular pH (IEA)

response to 3,3',5-triiodo-L-thyronine (ISO)

response to curcumin (ISO)

response to manganese ion (ISO)

Cellular Component

cell surface (IEA,ISO)

cytoplasm (IEA)

membrane (IEA)

membrane raft (ISO)

mitochondrial inner membrane (ISO)

mitochondrial membrane (IEA)

mitochondrial nucleoid (IEA)

mitochondrion (IEA)

plasma membrane (IEA)

proton-transporting ATP synthase complex (IEA)

proton-transporting ATP synthase complex, catalytic core F(1) (IEA,ISO)

proton-transporting two-sector ATPase complex (IEA)

transmembrane transporter complex (IEA)

Molecular Function

ADP binding (ISO)

angiostatin binding (IEA)

ATP binding (IEA,ISO)

ATP hydrolysis activity (IEA,ISO)

calcium ion binding (ISO)

lipoprotein particle receptor activity (ISO)

MHC class I protein binding (IEA)

protein binding (ISO)

proton-transporting ATP synthase activity, rotational mechanism (IEA,ISO)

proton-transporting ATPase activity, rotational mechanism (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

electron transport chain pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ATP5F1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	37,680,429 - 37,689,113 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	37,677,947 - 37,685,879 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	32,264,570 - 32,272,419 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	32,519,749 - 32,527,753 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	32,519,749 - 32,527,753 (+)	Ensembl	panpan1.1		panPan2

ATP5F1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	56,638,175 - 56,645,984 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	56,638,175 - 56,645,984 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	57,031,959 - 57,039,768 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	55,318,226 - 55,326,119 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	55,318,227 - 55,326,119	NCBI
Celera	12	56,683,671 - 56,691,564 (-)	NCBI		Celera
Cytogenetic Map	12	q13.3	NCBI
HuRef	12	54,071,237 - 54,079,130 (-)	NCBI		HuRef
CHM1_1	12	56,999,492 - 57,007,379 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	56,606,172 - 56,613,970 (-)	NCBI		T2T-CHM13v2.0

Atp5f1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	127,919,176 - 127,926,257 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	127,919,142 - 127,926,260 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	128,083,307 - 128,090,388 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	128,083,273 - 128,090,391 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	127,520,363 - 127,527,444 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	127,486,256 - 127,493,337 (+)	NCBI		MGSCv36	mm8
Celera	10	130,478,043 - 130,485,124 (+)	NCBI		Celera
Cytogenetic Map	10	D3	NCBI
cM Map	10	76.39	NCBI

Atp5f1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	1,100,058 - 1,106,461 (+)	NCBI		GRCr8
mRatBN7.2	7	515,454 - 521,858 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	515,460 - 567,273 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	3,274,116 - 3,280,516 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	5,150,130 - 5,156,530 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	5,451,361 - 5,457,743 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	2,504,708 - 2,511,748 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	2,504,695 - 2,511,749 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	2,484,095 - 2,490,338 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	1,376,552 - 1,383,228 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	1,377,178 - 1,383,228 (+)	NCBI
Celera	7	394,648 - 401,125 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Atp5f1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	4,186,461 - 4,195,494 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955458	4,188,167 - 4,195,575 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATP5F1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	870,405 - 876,937 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	870,392 - 909,161 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	933,592 - 940,127 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	879,724 - 886,261 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	879,724 - 919,087 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	856,580 - 863,114 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	1,099,743 - 1,106,277 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	1,223,513 - 1,230,049 (-)	NCBI		UU_Cfam_GSD_1.0

Atp5f1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	57,911,328 - 57,918,999 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936646	951,009 - 959,516 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936646	951,236 - 958,907 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP5F1B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	21,984,580 - 21,992,407 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	21,984,750 - 21,992,393 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	23,659,081 - 23,666,726 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATP5F1B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	52,587,608 - 52,600,057 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	52,587,143 - 52,600,756 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	193,380,244 - 193,389,154 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atp5f1b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624802	11,399,474 - 11,409,700 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624802	11,400,288 - 11,408,785 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003824908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034935634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000051483 ⟹ ENSPPAP00000028635

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	32,519,749 - 32,527,753 (+)	Ensembl

RefSeq Acc Id:

XM_003824908 ⟹ XP_003824956

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	37,680,429 - 37,689,113 (+)	NCBI
NHGRI_mPanPan1	12	37,677,947 - 37,685,879 (+)	NCBI
Mhudiblu_PPA_v0	12	32,264,570 - 32,272,419 (+)	NCBI
PanPan1.1	12	32,519,749 - 32,527,753 (+)	NCBI

Sequence:

show sequence

GCAGCCAGTTCACCCAATGGACCTGCCTACTGCAGCGTAGGCCTCGCCTCAACGGCAGGAGAGC
AGGCGGCTGCGGTTGCTGCAGCCTTCAGTCTCCACCCGGACTACGCCATGTTGGGGCTTGTGGG
TCGGGTGGCCGCTGCTTCGGCCTCCGGGGCCTTGCGGGGACTCACCCCTTCAGCGTCGCTGCCC
CCAGCTCAGCTCTTACTGCGGGCCGCTCCGACGGCGGTCCATCCTGTCAGGGACTATGCGGCGC
AAACATCTCCTTCGCCAAAAGCAGGCGCCGCCACCGGGCGCATCGTGGCGGTCATTGGCGCAGT
GGTGGACGTCCAGTTTGATGAGGGACTACCACCAATTCTAAATGCCCTGGAAGTGCAAGGCAGG
GAGACCAGACTGGTTTTGGAGGTGGCCCAGCATTTGGGTGAGAGCACAGTAAGGACTATTGCTA
TGGATGGTACAGAAGGCTTGGTTAGAGGCCAGAAAGTACTGGATTCTGGTGCACCAATCAAAAT
TCCTGTTGGTCCTGAGACTTTGGGCAGAATCATGAATGTCATTGGAGAACCTATTGATGAAAGA
GGTCCCATCAAAACCAAACAATTTGCTCCCATTCATGCTGAGGCTCCAGAGTTCATGGAAATGA
GTGTTGAGCAGGAAATTCTGGTGACTGGTATCAAGGTTGTCGATCTGCTAGCTCCCTATGCCAA
GGGTGGCAAAATTGGGCTTTTTGGTGGTGCCGGAGTTGGCAAGACTGTACTGATCATGGAGTTA
ATCAACAATGTCGCCAAAGCCCATGGTGGTTACTCTGTGTTTGCTGGTGTTGGTGAGAGGACCC
GTGAAGGCAATGATTTATACCATGAAATGATTGAATCTGGTGTTATCAACTTAAAAGATGCCAC
CTCTAAGGTAGCGCTGGTATATGGTCAAATGAATGAACCACCTGGTGCTCGTGCCCGGGTAGCT
CTGACTGGACTGACTGTGGCTGAATACTTCAGAGACCAAGAAGGTCAAGATGTTCTGCTATTTA
TTGATAACATCTTTCGCTTCACCCAGGCTGGTTCAGAGGTGTCTGCATTATTGGGCCGAATCCC
TTCTGCTGTGGGCTATCAGCCTACCCTGGCCACTGACATGGGTACTATGCAGGAAAGAATTACC
ACTACCAAGAAGGGATCTATCACCTCTGTACAGGCTATCTATGTGCCTGCTGATGACTTGACTG
ACCCTGCCCCTGCTACTACGTTTGCCCATTTGGATGCTACCACTGTACTGTCGCGTGCCATTGC
TGAGCTGGGCATCTATCCAGCTGTGGATCCTCTAGACTCCACCTCTCGTATCATGGATCCCAAC
ATTGTTGGCAGTGAGCATTACGATGTTGCCCGTGGGGTGCAAAAGATCCTGCAGGACTACAAAT
CCCTCCAGGATATCATTGCCATCCTGGGTATGGATGAACTTTCTGAGGAAGATAAGTTGACTGT
GTCCCGTGCACGGAAAATACAGCGTTTCTTGTCTCAGCCATTCCAGGTTGCTGAGGTCTTCACA
GGTCATATGGGGAAGCTGGTACCCCTGAAGGAGACCATCAAAGGGTTCCAGCAGATTTTGGCAG
GTGAATATGACCATCTCCCAGAACAGGCCTTCTATATGGTGGGACCCATTGAAGAAGCTGTGGC
AAAAGCTGATAAGCTGGCTGAAGAGCATTCATCGTGAGGGGTCTTTGTCCTCTGTACTGTCCCT
CTCCTTGCCCCGAACCCAAAAAGCTTCATTTTTCTGTGTAGGCTGCACAAGAGCCTTGATTGAA
GATATATTCTTTCTGAACAGTATTTAAGGTTTCCAATAAAATGTACACCCCTCAGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003824956	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000028635
	ENSPPAP00000028635.1

RefSeq Acc Id:

XP_003824956 ⟸ XM_003824908

- UniProtKB:

A0A2R9BG76 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLGLVGRVAAASASGALRGLTPSASLPPAQLLLRAAPTAVHPVRDYAAQTSPSPKAGAATGRIV
AVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDS
GAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDL
LAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVI
NLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSA
LLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTV
LSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSE
EDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGP
IEEAVAKADKLAEEHSS

hide sequence

Ensembl Acc Id:

ENSPPAP00000028635 ⟸ ENSPPAT00000051483

Protein Domains

AAA+ ATPase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000037354	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000051483.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.10.170	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/TrEMBL
	ATP_synth_F1_bsu	UniProtKB/TrEMBL
	ATPase_a/bsu_AS	UniProtKB/TrEMBL
	ATPase_alpha/beta_chains	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_N	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_N_sf	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_nucl-bd	UniProtKB/TrEMBL
	ATPase_F1/V1_b/a_C	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
KEGG Report	pps:100968407	UniProtKB/TrEMBL
NCBI Gene	ATP5B	ENTREZGENE
PANTHER	ATP SYNTHASE	UniProtKB/TrEMBL
	ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	ATP-synt_ab	UniProtKB/TrEMBL
	ATP-synt_ab_N	UniProtKB/TrEMBL
	ATP-synt_VA_C	UniProtKB/TrEMBL
PIRSF	ATPase_subunit_beta	UniProtKB/TrEMBL
PROSITE	ATPASE_ALPHA_BETA	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	C-terminal domain of alpha and beta subunits of F1 ATP synthase	UniProtKB/TrEMBL
	SSF50615	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A0A2R9BG76	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-11-28	ATP5F1B	ATP synthase F1 subunit beta	ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB