TNFSF10 (TNF superfamily member 10)

Advanced Search (OLGA)

Gene: TNFSF10 (TNF superfamily member 10) Pan paniscus

Analyze

Symbol:

TNFSF10

Name:

TNF superfamily member 10

RGD ID:

11711830

Description:

ENCODES a protein that exhibits cytokine activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of cysteine-type endopeptidase activity (ortholog); PARTICIPATES IN Trail mediated signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); arteriosclerosis (ortholog); Brain Injuries (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	170,387,678 - 170,406,039 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	170,392,401 - 170,410,764 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	169,512,491 - 169,530,706 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	177,693,860 - 177,712,137 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	177,694,021 - 177,712,137 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

arteriosclerosis (ISO)

Brain Injuries (ISO)

Breast Neoplasms (ISO)

Colonic Neoplasms (ISO)

Colorectal Neoplasms (ISO)

COVID-19 (ISO)

Diabetic Nephropathies (ISO)

Endometrial Neoplasms (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Mammary Neoplasms (ISO)

Experimental Neoplasms (ISO)

Fanconi-Bickel syndrome (ISO)

glioblastoma (ISO)

hepatocellular carcinoma (ISO)

high grade glioma (ISO)

Human Influenza (ISO)

Kidney Neoplasms (ISO)

leukemia (ISO)

Liver Neoplasms (ISO)

lung adenocarcinoma (ISO)

Neoplasm Metastasis (ISO)

Neovascularization, Pathologic (ISO)

neuroblastoma (ISO)

osteoarthritis (ISO)

Ovarian Neoplasms (ISO)

pancreatic cancer (ISO)

polycystic ovary syndrome (ISO)

Prostatic Neoplasms (ISO)

renal cell carcinoma (ISO)

small cell carcinoma (ISO)

Spontaneous Abortions (ISO)

type 1 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell communication (IEA)

immune response (IEA)

male gonad development (ISO)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of canonical NF-kappaB signal transduction (IEA)

positive regulation of cysteine-type endopeptidase activity (ISO)

positive regulation of extrinsic apoptotic signaling pathway (IEA,ISO)

positive regulation of release of cytochrome c from mitochondria (IEA)

response to insulin (ISO)

signaling (IEA)

TRAIL-activated apoptotic signaling pathway (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA,ISO)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

cytokine activity (IEA)

identical protein binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

signaling receptor binding (IEA)

TRAIL binding (IEA)

tumor necrosis factor receptor binding (IEA)

tumor necrosis factor receptor superfamily binding (IEA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Trail mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

TNFSF10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	170,387,678 - 170,406,039 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	170,392,401 - 170,410,764 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	169,512,491 - 169,530,706 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	177,693,860 - 177,712,137 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	177,694,021 - 177,712,137 (-)	Ensembl	panpan1.1		panPan2

TNFSF10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	172,505,508 - 172,523,430 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	172,505,508 - 172,523,475 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	172,223,298 - 172,241,220 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	173,706,158 - 173,723,963 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	173,706,166 - 173,723,971	NCBI
Celera	3	170,621,889 - 170,639,888 (-)	NCBI		Celera
Cytogenetic Map	3	q26.31	NCBI
HuRef	3	169,593,908 - 169,611,904 (-)	NCBI		HuRef
CHM1_1	3	172,186,184 - 172,204,170 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	175,290,584 - 175,308,501 (-)	NCBI		T2T-CHM13v2.0

Tnfsf10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	27,371,226 - 27,393,814 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	27,371,177 - 27,396,576 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	27,317,077 - 27,339,665 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	27,317,028 - 27,342,427 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	27,215,999 - 27,238,587 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	27,508,150 - 27,530,738 (+)	NCBI		MGSCv36	mm8
Celera	3	27,279,765 - 27,300,536 (+)	NCBI		Celera
Cytogenetic Map	3	A3	NCBI
cM Map	3	10.82	NCBI

Tnfsf10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	112,136,550 - 112,155,903 (+)	NCBI		GRCr8
mRatBN7.2	2	110,199,835 - 110,227,239 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	110,207,916 - 110,225,135 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	116,863,492 - 116,880,479 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	114,976,052 - 114,993,034 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	109,691,219 - 109,708,034 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	113,008,008 - 113,026,899 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	113,007,549 - 113,026,899 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	132,726,333 - 132,742,550 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	113,204,303 - 113,221,550 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	113,149,265 - 113,166,510 (+)	NCBI
Celera	2	105,412,626 - 105,429,375 (+)	NCBI		Celera
Cytogenetic Map	2	q24	NCBI

Tnfsf10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	2,549,142 - 2,566,564 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	2,550,392 - 2,566,448 (-)	NCBI	ChiLan1.0	ChiLan1.0

TNFSF10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	36,719,249 - 36,734,989 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	36,670,849 - 36,735,060 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	45,731,787 - 45,747,520 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	36,803,929 - 36,819,723 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	36,802,389 - 36,820,029 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	36,742,701 - 36,758,427 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	36,711,390 - 36,727,143 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	36,969,308 - 36,985,009 (-)	NCBI		UU_Cfam_GSD_1.0

Tnfsf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	103,391,320 - 103,422,437 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936593	212,532 - 230,651 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936593	212,642 - 230,645 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TNFSF10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	110,983,298 - 111,038,324 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	111,021,952 - 111,103,060 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	119,874,763 - 119,882,251 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TNFSF10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	16,934,982 - 16,953,155 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	16,934,962 - 16,954,860 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	25,697,846 - 25,715,823 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tnfsf10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	50,531,915 - 50,550,528 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	50,534,284 - 50,550,279 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008957310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008957311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000058969 ⟹ ENSPPAP00000036079

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	177,694,021 - 177,712,137 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058975 ⟹ ENSPPAP00000036085

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	177,695,223 - 177,712,014 (-)	Ensembl

RefSeq Acc Id:

XM_008957310 ⟹ XP_008955558

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	170,387,678 - 170,405,878 (-)	NCBI
NHGRI_mPanPan1	3	170,392,401 - 170,410,564 (-)	NCBI
Mhudiblu_PPA_v0	3	169,512,491 - 169,530,706 (-)	NCBI
PanPan1.1	3	177,693,860 - 177,712,137 (-)	NCBI

Sequence:

show sequence

ACAGAACCCAGAAAAACAACTCATTCGCTTTCGTTTCCTCACTGACTATAAAAGAATAGAGAAG
GAAGAGCTTCAGTGACCGGCTGCCTGGCTGACTTACAGCAGTCAGACTCTGACAGGATCATGGC
TATGATGGAGGTCCAGGGGGGACCCAGCCTGGGACAGACCTGCGTGCTGATCGTGGTCTTCACA
GTGCTCCTGCAGTCTCTCTGTGTGGCTGTAACTTACGTGTACTTTACCAACGAGCTGAAGCAGA
TGCAGGACAAGTACTCCAAAAGTGGCATTGCTTGTTTCTTAAAAGAAGATGACAGTTATTGGGA
CCCCAATGACGAAGACAGTATGAACAGCCCCTGCTGGCAAGTCAAGTGGCAACTCCGTCAGCTC
GTTAGAAAGATGATTTTGAGAACCTCTGAGGAAACCATTTCTACAGTTCAAGAAAAGCAACAAA
ATATTTCTCCCCTAGTGAGAGAAAGAGGTCCTCAGAGAGTAGCAGCTCACATAACTGGAACCAG
AGGAAGAAGCAACACATTGTCTTCTCCAAACTCCAAGAATGAAAAGGCTCTGGGCCACAAAATA
AACTCCTGGGAATCATCAAGGAGTGGGCATTCATTCCTGAGCAACTTGCACTTGAGGAATGGCG
AACTGGTCATCCATGAAAAAGGGTTTTACTACATCTATTCCCAAACATACTTTCGATTTCAGGA
GGAAATAAAAGAAAACACAAAGAACGACAAACAAATGGTCCAATATATTTACAAATACACAAGT
TATCCTGACCCTATATTGTTGATGAAAAGCGCTAGAAATAGTTGTTGGTCTAAAGATGCAGAAT
ATGGACTCTATTCCATCTATCAAGGGGGAATATTTGAGCTTAAGGAAAATGACAGAATTTTTGT
TTCTGTAACAAATGAGCACTTGATAGACATGGACCATGAAGCCAGTTTTTTCGGGGCCTTTTTA
GTTGGCTAACTGACCTGGAAAGAAAAAGCAATAACCTCAAAGTGACTATTCAGTTTTCAGGATG
ATACACTATGAAGATGTTTCAAAAAATCTGACCAAAACAAACAAACAGAAAACAGAAAACAAAA
AAACCTCTATGCAATCTGAGTAGAGCAGCCACAACCAAAAAATTCTACAACACACACTGTTCTG
AAAGTGACTCACTTATCCCAAGAAAATGAAATTGCTGAAAGATCTTTCAGGACTCTACCTCATA
TCAGTTTGCTAGCAGAAATCTAGAAGACTGTCAGCTTCCAAACATTAATGCAATGGTTAACATC
TTCTGTCTTTATAATCTACTCCTTGTAAAGACTGTAGAAGAAAGAGCAACAATCCATCTCTCAA
GTAGTGTATCACAGTAGTAGCCTCCAGGTTTCCTTAAGGGACAACATCCTTAAGTCAAAAGAGA
GAAGAGGCACCACTAAAAGATCGCGGTTTGCCTGGTGCAGTGGCTCACGCCTATAATCCCAACA
TTTTGGGAACCCAAGGTGGGTAGATCACGAGGTCAAGAGATCAAGACCATAGTGACCAACATAG
TGAAACCCCATCTCTACTGAAAGTACAAAAATTAGCTGGGTGTGTTGGCACATGCCTGTAGTCC
CAGCTACTTGAGAGGCTGAGGCAGGAGAATCGTTTGAACCCGGGAGGCAGAGGTTGCAGTGTGG
TGAGATCATGCCACTACACTCCAGCCTGGCGACAGAGCGAGACTTGGTTTCAAAAAAAAAAAAA
CTTCAGTAAGTACGTGTTTATTTTTTCAATAAAATTCTATTACAGTATGTCGTGTTTGCTGTAG
TGCTCATATTTATTGTTGTTTTTGTTTTAGTACTCACTTGTTTCATAATATCAAGATTACTAAA
AATGGGGGAAAAGACTTCTAATCTTTTTTCATAATATCTTTGACACATATTACAGAATAAATAA
ATTTCTTACTTTTAATTTAA

hide sequence

RefSeq Acc Id:

XM_008957311 ⟹ XP_008955559

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	170,397,332 - 170,406,039 (-)	NCBI
NHGRI_mPanPan1	3	170,402,050 - 170,410,764 (-)	NCBI
Mhudiblu_PPA_v0	3	169,523,395 - 169,530,700 (-)	NCBI
PanPan1.1	3	177,705,939 - 177,712,104 (-)	NCBI

Sequence:

show sequence

TTTCCTCACTGACTATAAAAGAATAGAGAAGGAAGAGCTTCAGTGACCGGCTGCCTGGCTGACT
TACAGCAGTCAGACTCTGACAGGATCATGGCTATGATGGAGGTCCAGGGGGGACCCAGCCTGGG
ACAGACCTGCGTGCTGATCGTGGTCTTCACAGTGCTCCTGCAGTCTCTCTGTGTGGCTGTAACT
TACGTGTACTTTACCAACGAGCTGAAGCAGTTTGCAGAAAATGATTGCCAGAGACTAATGTCTG
GGCAGCAGACAGGGTCATTGCTGCCATCTTGAAGTCTACCTTGCTGAGTCTACCTTGCTGAGTC
TACCCTGCTGACCTCAAGCCCCATCAAGGACTGGTTGACCCTGGCCTAGACAACCACCGTGTTT
GTAACAGCACCAAGAGCAGTCGCCATGGAAATCCACTTTTCAGAACCAAGGGCTTCTGGAGCTG
AAGAACAGGCACCCAGTGCAAGAGCTTTCTTTTCAGAGGCACGCAAATGAAAATAATCCCCACA
CGCTACCTTCTGCCCCCAGTGCCCAGGTGTGGTTAGTTAGAGAATATAGCCTCAGCCTATGATA
TGCTGCAGGAAACTCATACTTTGAAGTGGAAAGGATGGGAGGAGGCGGGGGGAGACATATCGTA
TTAATTATCATTCTTGGAATAACCACAGCACCTCACGTTAACCCGCCATGTGTCTAGTCACCAG
CATTGGCCAAGTTCTATAGGAGAAACTACCAAAATTCATGATGCAAGAAACATGTGAGGGTGGA
GAGAGTGACTGGGGCTTCCTCTCTGGATTTCTATTGTTCAGAAATCAATATTTATGCATAAAAA
GGTCTAGAAAGAGAAACACCAAAATGACAATGTGATCTCTAGATGGTATGATTATGGGTACTTT
TTTTCCATTTTATTTTTCTATATTTTACAAATTTTCTACAGGGAATGTCATAAAAATATCTATG
CTATCCATGTATAATTTTCATATAGATTTAAAGAACACAGCATTTTTATATAGTCTTATGAGAA
AACAACCATACTCAAAATTATGCACACACACAGTCTGATCTCACCCCTGTAAACAAGAGATATC
ATCCAAAGGTTAACTAGGAGGTGAGAATATAGCTGCTATTAGTGGTTGTTTTGTTTTGTTTTGT
TTTGTTTTGTGATTTACTTATTTAGTTTTTGGAGGGTTTTTTTTTTCTTTTAGAAAAGTGTTCT
TTACTTTTCCATGCTTCCCTGCTTGCCTGTGTATCCTGAATGTATCCAGGCTTTATAAACTCCT
GGGTAATAATGTAGCTACATTAACTTGTTTACCTCCCATCCACTTATACCCAGGACCTTACTCA
ATTTTCCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008955558	(Get FASTA)	NCBI Sequence Viewer
	XP_008955559	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000036079
	ENSPPAP00000036079.1
	ENSPPAP00000036085.1

RefSeq Acc Id:	XP_008955558 ⟸ XM_008957310
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9C2U3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAMMEVQGGPSLGQTCVLIVVFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKEDDSY WDPNDEDSMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHITG TRGRSNTLSSPNSKNEKALGHKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRF QEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRI FVSVTNEHLIDMDHEASFFGAFLVG hide sequence

RefSeq Acc Id:	XP_008955559 ⟸ XM_008957311
- Peptide Label:	isoform X2
- Sequence:	show sequence MAMMEVQGGPSLGQTCVLIVVFTVLLQSLCVAVTYVYFTNELKQFAENDCQRLMSGQQTGSLLP S hide sequence

Ensembl Acc Id:

ENSPPAP00000036079 ⟸ ENSPPAT00000058969

Ensembl Acc Id:

ENSPPAP00000036085 ⟸ ENSPPAT00000058975

Protein Domains

THD

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040821	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000058969.1	UniProtKB/TrEMBL
	ENSPPAT00000058975.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.40	UniProtKB/TrEMBL
InterPro	TNF_CS	UniProtKB/TrEMBL
	TNF_dom	UniProtKB/TrEMBL
	TNF_ligand_10/11	UniProtKB/TrEMBL
	Tumour_necrosis_fac-like_dom	UniProtKB/TrEMBL
KEGG Report	pps:100986991	UniProtKB/TrEMBL
NCBI Gene	TNFSF10	ENTREZGENE
PANTHER	TUMOR NECROSIS FACTOR FAMILY MEMBER	UniProtKB/TrEMBL
	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10	UniProtKB/TrEMBL
Pfam	TNF	UniProtKB/TrEMBL
PIRSF	TNF10_TNF11	UniProtKB/TrEMBL
PROSITE	TNF_1	UniProtKB/TrEMBL
	TNF_2	UniProtKB/TrEMBL
SMART	TNF	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49842	UniProtKB/TrEMBL
UniProt	A0A2R9C2D0_PANPA	UniProtKB/TrEMBL
	A0A2R9C2U3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-03-08	TNFSF10	TNF superfamily member 10		tumor necrosis factor superfamily member 10	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)