TNFRSF1A (TNF receptor superfamily member 1A)

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Gene: TNFRSF1A (TNF receptor superfamily member 1A) Pan paniscus

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Symbol:

TNFRSF1A

Name:

TNF receptor superfamily member 1A

RGD ID:

11940201

Description:

ENCODES a protein that exhibits protease binding (ortholog); protein-containing complex binding (ortholog); tumor necrosis factor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); cellular response to estradiol stimulus (ortholog); cytokine-mediated signaling pathway (ortholog); PARTICIPATES IN ceramide signaling pathway; nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH acne (ortholog); acquired immunodeficiency syndrome (ortholog); Acute Experimental Pancreatitis (ortholog); FOUND IN axon (ortholog); cell surface (ortholog); extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tumor necrosis factor receptor superfamily member 1A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	11,888,472 - 11,902,332 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	11,885,230 - 11,898,580 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	6,457,617 - 6,470,969 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	6,374,256 - 6,387,613 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	6,374,257 - 6,387,613 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acne (ISO)

acquired immunodeficiency syndrome (ISO)

Acute Experimental Pancreatitis (ISO)

acute kidney failure (ISO)

adult respiratory distress syndrome (ISO)

allergic bronchopulmonary aspergillosis (ISO)

allergic disease (ISO)

Alzheimer's disease (ISO)

amyloidosis (ISO)

anemia (ISO)

Anorexia (ISO)

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (ISO)

arteriosclerosis (ISO)

asthma (ISO)

autoimmune disease (ISO)

autosomal dominant familial periodic fever (ISO)

bacterial pneumonia (ISO)

Behcet's disease (ISO)

Brain Injuries (ISO)

brain ischemia (ISO)

bronchiectasis 1 (ISO)

Cachexia (ISO)

CHARGE syndrome (ISO)

Chediak-Higashi syndrome (ISO)

Chronic Hepatitis C (ISO)

chronic obstructive pulmonary disease (ISO)

colon carcinoma (ISO)

colorectal adenoma (ISO)

congestive heart failure (ISO)

coronary artery disease (ISO)

COVID-19 (ISO)

Crohn's disease (ISO)

cryptogenic organizing pneumonia (ISO)

cystic fibrosis (ISO)

cytomegalovirus retinitis (ISO)

Diabetic Nephropathies (ISO)

Embryo Loss (ISO)

End Stage Liver Disease (ISO)

end stage renal disease (ISO)

endometrial cancer (ISO)

Enterovirus Infections (ISO)

Experimental Arthritis (ISO)

Experimental Autoimmune Uveoretinitis (ISO)

Experimental Colitis (ISO)

Experimental Diabetes Mellitus (ISO)

extrinsic allergic alveolitis (ISO)

familial Mediterranean fever (ISO)

Febrile Seizures (ISO)

Fever (ISO)

fibrosarcoma (ISO)

focal segmental glomerulosclerosis (ISO)

genetic disease (ISO)

glomerulonephritis (ISO)

Human Influenza (ISO)

Hyperalgesia (ISO)

Hyperoxia (ISO)

Hyperphosphatemic Familial Tumoral Calcinosis 1 (ISO)

IgA glomerulonephritis (ISO)

Insulin Resistance (ISO)

ischemia (ISO)

kidney disease (ISO)

Kidney Reperfusion Injury (ISO)

Legionnaires' disease (ISO)

Liver Reperfusion Injury (ISO)

Lung Injury (ISO)

lung non-small cell carcinoma (ISO)

lupus nephritis (ISO)

lymphoproliferative syndrome 2 (ISO)

Metabolic Syndrome (ISO)

middle cerebral artery infarction (ISO)

multiple sclerosis (ISO)

Muscle Weakness (ISO)

myocardial infarction (ISO)

Nasal Polyps (ISO)

Nematode Infections (ISO)

Neurogenic Inflammation (ISO)

obesity (ISO)

obstructive sleep apnea (ISO)

Optic Nerve Injuries (ISO)

ovarian cancer (ISO)

Pain (ISO)

peroxisome biogenesis disorder 2B (ISO)

pneumonia (ISO)

polymyositis (ISO)

primary biliary cholangitis (ISO)

Pseudohypoaldosteronism Type IB1, Autosomal Recessive (ISO)

Pseudomonas Infections (ISO)

psoriasis (ISO)

Radiation Pneumonitis (ISO)

renal cell carcinoma (ISO)

renal fibrosis (ISO)

Reperfusion Injury (ISO)

retinal detachment (ISO)

rheumatoid arthritis (ISO)

root resorption (ISO)

sciatic neuropathy (ISO)

silicosis (ISO)

Spinal Cord Compression (ISO)

Spinal Cord Injuries (ISO)

squamous cell carcinoma (ISO)

systemic lupus erythematosus (ISO)

Temtamy syndrome (ISO)

transient cerebral ischemia (ISO)

type 2 diabetes mellitus (ISO)

ureteral obstruction (ISO)

uveitis (ISO)

visual epilepsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aortic valve development (IEA)

apoptotic process (IEA)

cell surface receptor signaling pathway (IEA,ISO)

cell surface receptor signaling pathway via JAK-STAT (IEA)

cellular response to estradiol stimulus (ISO)

cellular response to mechanical stimulus (IEA)

cytokine-mediated signaling pathway (IEA,ISO)

defense response (IEA,ISO)

defense response to bacterium (IEA,ISO)

inflammatory response (IEA,ISO)

intrinsic apoptotic signaling pathway in response to DNA damage (IEA,ISO)

negative regulation of apoptotic process (ISO)

negative regulation of cardiac muscle hypertrophy (IEA)

negative regulation of extracellular matrix constituent secretion (IEA)

negative regulation of gene expression (ISO)

negative regulation of inflammatory response (IEA)

negative regulation of interleukin-6 production (ISO)

positive regulation of amide metabolic process (IEA)

positive regulation of angiogenesis (ISO)

positive regulation of apoptotic process involved in morphogenesis (IEA)

positive regulation of canonical NF-kappaB signal transduction (IEA)

positive regulation of execution phase of apoptosis (IEA)

positive regulation of gene expression (ISO)

positive regulation of inflammatory response (IEA,ISO)

positive regulation of lipid metabolic process (IEA)

positive regulation of neuron apoptotic process (ISO)

positive regulation of protein import into nucleus (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of tumor necrosis factor production (ISO)

prostaglandin metabolic process (IEA)

protein localization to plasma membrane (IEA)

pulmonary valve development (IEA)

regulation of apoptotic process (ISO)

regulation of establishment of endothelial barrier (IEA)

regulation of membrane lipid metabolic process (IEA)

regulation of tumor necrosis factor-mediated signaling pathway (IEA,ISO)

response to alkaloid (ISO)

response to amino acid (ISO)

response to ethanol (ISO)

response to hypoxia (ISO)

response to lipopolysaccharide (ISO)

signal transduction (IEA)

transcription by RNA polymerase II (IEA,ISO)

tumor necrosis factor-mediated signaling pathway (IEA,ISO)

Cellular Component

axon (ISO)

cell surface (IEA,ISO)

extracellular space (IEA,ISO)

Golgi apparatus (IEA)

Golgi membrane (IEA)

membrane raft (IEA)

plasma membrane (IEA,ISO)

protein-containing complex (ISO)

receptor complex (IEA)

Molecular Function

protease binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

signaling receptor activity (IEA)

tumor necrosis factor binding (IEA,ISO)

tumor necrosis factor receptor activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ceramide signaling pathway (ISO)

nuclear factor kappa B signaling pathway (ISO)

tumor necrosis factor mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

TNFRSF1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	11,888,472 - 11,902,332 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	11,885,230 - 11,898,580 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	6,457,617 - 6,470,969 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	6,374,256 - 6,387,613 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	6,374,257 - 6,387,613 (-)	Ensembl	panpan1.1		panPan2

TNFRSF1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	6,328,771 - 6,342,076 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	6,328,757 - 6,342,114 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	6,437,937 - 6,451,242 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	6,308,184 - 6,321,522 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	6,308,184 - 6,321,522	NCBI
Celera	12	8,054,567 - 8,067,927 (-)	NCBI		Celera
Cytogenetic Map	12	p13.31	NCBI
HuRef	12	6,291,179 - 6,304,533 (-)	NCBI		HuRef
CHM1_1	12	6,437,153 - 6,450,509 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	6,338,163 - 6,351,461 (-)	NCBI		T2T-CHM13v2.0

Tnfrsf1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	125,326,686 - 125,339,446 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	125,326,325 - 125,339,447 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	125,349,723 - 125,362,483 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	125,349,362 - 125,362,484 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	125,299,741 - 125,312,501 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	125,315,374 - 125,328,104 (+)	NCBI		MGSCv36	mm8
Celera	6	127,020,792 - 127,033,747 (+)	NCBI		Celera
Cytogenetic Map	6	F3	NCBI
cM Map	6	59.32	NCBI

Tnfrsf1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	159,837,119 - 159,849,817 (+)	NCBI		GRCr8
mRatBN7.2	4	158,150,815 - 158,163,592 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	158,150,820 - 158,163,591 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	164,380,489 - 164,393,199 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	160,163,415 - 160,176,125 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	158,802,250 - 158,814,961 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	157,864,905 - 157,877,634 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	157,864,969 - 157,877,633 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	224,881,368 - 224,894,089 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	162,172,563 - 162,185,252 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	162,417,498 - 162,430,188 (+)	NCBI
Celera	4	146,886,949 - 146,899,646 (+)	NCBI		Celera
RH 3.4 Map	4	1000.9	RGD
Cytogenetic Map	4	q42	NCBI

Tnfrsf1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	3,981,400 - 3,996,021 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	3,982,670 - 3,996,320 (-)	NCBI	ChiLan1.0	ChiLan1.0

TNFRSF1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	38,641,837 - 38,654,693 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	38,638,753 - 38,700,282 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	7,959,778 - 7,972,628 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	38,997,951 - 39,010,819 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	27	38,870,492 - 38,883,352 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	38,911,954 - 38,924,837 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	7,438,485 - 7,451,382 (-)	NCBI		UU_Cfam_GSD_1.0

Tnfrsf1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	102,735,979 - 102,753,899 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936709	1,407,278 - 1,421,921 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936709	1,407,327 - 1,421,448 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TNFRSF1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	64,319,051 - 64,331,909 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	64,319,349 - 64,331,876 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	66,780,726 - 66,793,255 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TNFRSF1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	6,364,544 - 6,378,880 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	6,364,330 - 6,378,902 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	1,856,767 - 1,871,090 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tnfrsf1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624860	3,111,630 - 3,122,711 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624860	3,111,244 - 3,123,041 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008973744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000019582 ⟹ ENSPPAP00000004217

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	6,374,257 - 6,387,613 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000019591 ⟹ ENSPPAP00000004218

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	6,374,801 - 6,387,309 (-)	Ensembl

RefSeq Acc Id:

XM_008973744 ⟹ XP_008971992

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	11,888,472 - 11,902,332 (-)	NCBI
NHGRI_mPanPan1	12	11,885,230 - 11,898,580 (-)	NCBI
Mhudiblu_PPA_v0	12	6,457,617 - 6,470,969 (-)	NCBI
PanPan1.1	12	6,374,256 - 6,387,613 (-)	NCBI

Sequence:

show sequence

CTCCTCCAGCTCTTCCTGTCCCGCTGTTGCAACACCGCCTCACTCTTCCCCTCCCACCTTCTCT
CCCCTCCTCTCTGCTTTAATTTTCTCAGAATTCTCTGGACTCAGGCTCCAGTTCTGGCCTTTGG
GGTTCAAGATCACTGGGACCAGGCCGTGATCTCTATGCCCGAGTCTCAACCCTCAACTGTCACC
CCAAGGCACTTGGGACGTCCTGGACAGACCGAGTCCCGGGAAGCCTCCAGCACTGCCGCTGCCA
CACTGCCCTGAGCCCAAATGGGGGAGTGAGAGGCCATAGCTGTCTGGCATGGGCCTCTCCACCG
TGCCTGACCTGCTGCTGCCACTGGTGCTCCTGGAGCTGTTGGTGGGAATATACCCCTCAGGGGT
TATTGGACTGGTCCCTCACCTAGGGGACAGGGAGAAGAGAGATAGTGTGTGTCCCCAAGGAAAA
TATATCCACCCTCAAAATAATTCTATTTGCTGTACCAAGTGCCACAAAGGAACCTACTTGTACA
ATGACTGTCCAGGCCCGGGGCAGGATACGGACTGCAGGGAGTGTGAGAGCGGCTCCTTCACCGC
TTCAGAAAACCACCTCAGACACTGCCTCAGCTGCTCCAAATGCCGAAAGGAAATGGGTCAGGTG
GAGATCTCTTCTTGCACAGTGGACCGGGACACCGTGTGTGGCTGCAGGAAGAACCAGTACCGGC
ATTATTGGAGTGAAAACCTTTTCCAGTGCTTCAATTGCAGCCTCTGCCTCAATGGGACCGTGCA
CCTCTCCTGCCAGGAGAAACAGAACACCGTGTGCACCTGCCATGCAGGGTTCTTTCTAAGAGAA
AACGACTGTGTCTCCTGTAGTAACTGTAAGAAAAGCCTGGAGTGCACGAAGTTGTGCCTACCCC
AGATTGAGAATGTTAAGGGCACTGAGGACTCAGGCACCACAGTGCTGTTGCCCCTGGTCATCTT
CTTTGGTCTTTGCCTTTTATCCCTCCTCTTCATTGGTTTAATGTATCGCTACCAACGGTGGAAG
TCCAAGCTCTACTCCATTGTTTGTGGGAAATCGACACCTGAAAAAGAGGGGGAGCTTGAAGGAA
CTACTACTAAGCCCCTGGCCCCAACCCCAAGCTTCAGTCCCACTCCAGGCTTCACCCCCACCCT
GGGCTTCAGTCCCGTGCCCAGTTCCACCTTCACCTCCAGCTCCACCTATACCCCCGGTGACTGT
CCCAACTTTGCGGCTCCCCGCAGAGAGGTGGCACCACCCTATCAGGGGGCTGACCCCATCCTTG
CGACAGCCCTCGCCTCCGACCCCATCCCCAACCCCCTTCAGAAGTGGGAGGACAGCGCCCACAA
GCCACAGAGCCTAGACACTGATGACCCCGCGACGCTGTACGCCGTGGTGGAGAACGTGCCCCCG
TTGCGCTGGAAGGAATTCGTGCGGCGCCTAGGGCTGAGCGACCACGAGATCGATCGGCTGGAGC
TGCAGAACGGGCGCTGCCTGCGCGAGGCGCAATACAGCATGCTGGCGACCTGGAGGCGGCGCAC
GCCGCGGCGCGAGGCCACGCTGGAGCTGCTGGGACGCGTGCTCCGCGACATGGACCTGCTGGGC
TGCCTGGAGGACATCGAGGAGGCGCTTTGCGGCCCCGCCGCCCTCCCGCCCGCGCCCAGTCTTC
TCAGATGAGGCTGCGCCCCTGCGGGCAGCTCTAAGGACCGTCCTGCGAGATCGCCTTCCAACCC
CACTTTTTTCTGGAAAGGAGGGGTCCTGGAGGGGCAAGCAGGAGCTAGCAGCCGCCTACTTGGT
GCTAACCCCTCGATGTACATAGCTTTTCTCAGCTGCCTGCGCGCCGCCGGCAGTCAGCGCTGTG
CGCGCGGAGAGAGGTGCGCCGTGGGCTCAAGAGCCTGAGTGGGTGGTTTGCGAGGATGAGGGAC
GCTATGCCTCATGCCCGTTTTGGGTGTCCTCACCAGCAAGGCTGCTCGGGGGCCCCTGGTTCGT
CCCTGAGCCTTTTTCACAGTACATAAGCAGTTTTTTTGTTTTTGTTTTGTTTTGTTTTGTTTTT
AAATCAATCATGTTACACTAATAGAAACTTGGCACTCCTGTGCCCTCTGCCTGGACAAGCACAT
AGCAAGCTGAACTGTCCTAAGGCAGGGGCGAGCACGGAACAACGGGGCCTTCAGCTGGAGCTGT
GGACTTTTGTACATACACTAAAATTCTGAAGTTAAAGCTCT

hide sequence

Protein Sequences


Protein RefSeqs	XP_008971992	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000004217
	ENSPPAP00000004217.1
	ENSPPAP00000004218.1

RefSeq Acc Id:

XP_008971992 ⟸ XM_008973744

- UniProtKB:

A0A2R8ZK33 (UniProtKB/TrEMBL), A0A2R8ZN58 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHK
GTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCR
KNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENDCVSCSNCKKSLECT
KLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKE
GELEGTTTKPLAPTPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQG
ADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHE
IDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEALCGPAALP
PAPSLLR

hide sequence

Ensembl Acc Id:

ENSPPAP00000004218 ⟸ ENSPPAT00000019591

Ensembl Acc Id:

ENSPPAP00000004217 ⟸ ENSPPAT00000019582

Protein Domains

Death TNFR-Cys

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000017841	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000019582.1	UniProtKB/TrEMBL
	ENSPPAT00000019591.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.533.10	UniProtKB/TrEMBL
	Tumor Necrosis Factor Receptor, subunit A, domain 2	UniProtKB/TrEMBL
InterPro	DEATH-like_dom_sf	UniProtKB/TrEMBL
	Death_domain	UniProtKB/TrEMBL
	TNFR/NGFR_Cys_rich_reg	UniProtKB/TrEMBL
	TNFR_1A	UniProtKB/TrEMBL
	TNFRSF1A	UniProtKB/TrEMBL
	TNFRSF1A_death	UniProtKB/TrEMBL
	TNFRSF1A_N	UniProtKB/TrEMBL
KEGG Report	pps:100983212	UniProtKB/TrEMBL
NCBI Gene	TNFRSF1A	ENTREZGENE
PANTHER	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A	UniProtKB/TrEMBL
	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A	UniProtKB/TrEMBL
Pfam	Death	UniProtKB/TrEMBL
	TNFR_c6	UniProtKB/TrEMBL
PRINTS	TNFACTORR1A	UniProtKB/TrEMBL
PROSITE	DEATH_DOMAIN	UniProtKB/TrEMBL
	TNFR_NGFR_1	UniProtKB/TrEMBL
	TNFR_NGFR_2	UniProtKB/TrEMBL
SMART	DEATH	UniProtKB/TrEMBL
	TNFR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47986	UniProtKB/TrEMBL
	TNF receptor-like	UniProtKB/TrEMBL
UniProt	A0A2R8ZK33	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZN58	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)