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Gene: MME (membrane metalloendopeptidase) Pan paniscus
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Symbol: MME
Name: membrane metalloendopeptidase
RGD ID: 11729366
Description: ENCODES a protein that exhibits cardiolipin binding (ortholog); endopeptidase activity (ortholog); exopeptidase activity (ortholog); INVOLVED IN aging (ortholog); amyloid-beta clearance (ortholog); amyloid-beta clearance by cellular catabolic process (ortholog); PARTICIPATES IN angiotensin (1-7) signaling pathway; kallikrein-kinin cascade pathway; renin-angiotensin cascade pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Breast Neoplasms (ortholog); cerebellar ataxia type 43 (ortholog); FOUND IN axon (ortholog); brush border (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: neprilysin
Orthologs:
Homo sapiens (human) : MME (membrane metalloendopeptidase)  HGNC  Alliance
Mus musculus (house mouse) : Mme (membrane metallo endopeptidase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mme (membrane metallo-endopeptidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mme (membrane metalloendopeptidase)
Canis lupus familiaris (dog) : MME (membrane metalloendopeptidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mme (membrane metalloendopeptidase)
Sus scrofa (pig) : MME (membrane metalloendopeptidase)
Chlorocebus sabaeus (African green monkey) : MME (membrane metalloendopeptidase)
Heterocephalus glaber (naked mole-rat) : Mme (membrane metalloendopeptidase)
more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13159,637,965 - 160,292,119 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,197,566 - 160,292,119 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03152,085,694 - 152,240,148 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Genomics

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Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on MME
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11729366
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.