MPZ (myelin protein zero) - Rat Genome Database

Send us a Message



Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: MPZ (myelin protein zero) Pan paniscus
Analyze
Symbol: MPZ
Name: myelin protein zero
RGD ID: 11861635
Description: INVOLVED IN cell-cell junction maintenance (ortholog); myelination (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); atrophic muscular disease (ortholog); autosomal dominant distal hereditary motor neuronopathy 2 (ortholog); FOUND IN basolateral plasma membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: myelin protein P0
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,543,449 - 88,573,944 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,233,764 - 88,264,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,691,245 - 136,720,958 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,603,609 - 140,631,273 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,626,039 - 140,631,273 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MPZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,543,449 - 88,573,944 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,233,764 - 88,264,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,691,245 - 136,720,958 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,603,609 - 140,631,273 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,626,039 - 140,631,273 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
MPZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,303,600 - 161,309,968 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,304,735 - 161,309,974 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371161,274,525 - 161,279,758 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,541,151 - 159,546,377 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341158,087,599 - 158,092,817NCBI
Celera1134,341,666 - 134,346,903 (-)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,631,395 - 132,636,601 (-)NCBIHuRef
CHM1_11162,670,753 - 162,675,990 (-)NCBICHM1_1
T2T-CHM13v2.01160,441,004 - 160,447,413 (-)NCBIT2T-CHM13v2.0
Mpz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,978,282 - 170,988,699 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,978,280 - 170,988,699 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381171,150,713 - 171,161,130 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,150,711 - 171,161,130 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv371173,080,844 - 173,091,254 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361172,987,388 - 172,997,798 (+)NCBIMGSCv36mm8
Celera1173,598,959 - 173,609,357 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.05NCBI
Mpz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,103,290 - 86,109,156 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1386,103,290 - 86,109,155 (+)EnsemblGRCr8
mRatBN7.21383,570,811 - 83,576,680 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,570,811 - 83,576,679 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1386,076,519 - 86,082,418 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,474,755 - 87,480,657 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,706,501 - 84,712,211 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1385,471,212 - 85,477,075 (+)NCBI
Lyon_Normotensive1385,682,307 - 85,688,173 (+)NCBI
Lyon_Hypertensive1385,612,871 - 85,618,737 (+)NCBI
F344_StmMcwi1385,677,380 - 85,683,255 (+)NCBI
Rnor_6.01389,524,204 - 89,530,070 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,524,329 - 89,530,068 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01394,151,850 - 94,156,749 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41387,040,479 - 87,045,378 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1383,202,202 - 83,207,991 (+)NCBICelera
RGSC_v3.11387,229,362 - 87,234,262 (+)NCBI
Cytogenetic Map13q24NCBI
Mpz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546813,041,011 - 13,047,284 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495546813,041,911 - 13,047,026 (-)NCBIChiLan1.0ChiLan1.0
MPZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,205,339 - 21,210,439 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,205,107 - 21,210,451 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3821,280,251 - 21,285,323 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03821,323,207 - 21,328,277 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,323,098 - 21,328,270 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,220,355 - 21,225,416 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,626,466 - 21,631,518 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,034,738 - 22,039,792 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mpz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap111116,655,280 - 116,660,506 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_0244050587,375,284 - 7,380,521 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903583,942 - 589,160 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936903583,942 - 589,160 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,169,311 - 89,179,925 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1489,174,107 - 89,179,556 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,031,478 - 97,036,934 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1201,980,582 - 1,985,793 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_0236660381,720,210 - 1,725,435 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1202,662,163 - 2,668,393 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,665,737 - 2,668,393 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Mpz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624794101,095 - 106,508 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_004624794100,824 - 106,444 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl2818,855,437 - 18,861,746 (+)Ensembl
Mpz
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11050,316,357 - 50,322,011 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000051467   ⟹   ENSPPAP00000028619
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1140,626,039 - 140,631,273 (-)Ensembl
RefSeq Acc Id: XM_003811824   ⟹   XP_003811872
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,462 - 88,551,845 (+)NCBI
NHGRI_mPanPan1188,233,773 - 88,251,725 (+)NCBI
Mhudiblu_PPA_v01136,712,500 - 136,720,945 (-)NCBI
PanPan1.11140,626,039 - 140,631,273 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034939019   ⟹   XP_034794910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,456 - 88,551,845 (+)NCBI
NHGRI_mPanPan1188,233,769 - 88,239,405 (+)NCBI
Mhudiblu_PPA_v01136,715,333 - 136,720,953 (-)NCBI
RefSeq Acc Id: XM_055112352   ⟹   XP_054968327
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,449 - 88,573,944 (+)NCBI
NHGRI_mPanPan1188,233,764 - 88,264,228 (+)NCBI
RefSeq Acc Id: XM_055112355   ⟹   XP_054968330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,450 - 88,573,944 (+)NCBI
NHGRI_mPanPan1188,233,765 - 88,264,228 (+)NCBI
RefSeq Acc Id: XM_055112359   ⟹   XP_054968334
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,449 - 88,562,675 (+)NCBI
NHGRI_mPanPan1188,233,765 - 88,252,963 (+)NCBI
RefSeq Acc Id: XR_004666573
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,451 - 88,573,944 (+)NCBI
NHGRI_mPanPan1188,233,766 - 88,264,228 (+)NCBI
Mhudiblu_PPA_v01136,691,245 - 136,720,958 (-)NCBI
RefSeq Acc Id: XR_010112120
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,449 - 88,564,383 (+)NCBI
RefSeq Acc Id: XR_010112121
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,451 - 88,571,556 (+)NCBI
RefSeq Acc Id: XP_003811872   ⟸   XM_003811824
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BG50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034794910   ⟸   XM_034939019
- Peptide Label: isoform X3
Ensembl Acc Id: ENSPPAP00000028619   ⟸   ENSPPAT00000051467
RefSeq Acc Id: XP_054968327   ⟸   XM_055112352
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054968330   ⟸   XM_055112355
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054968334   ⟸   XM_055112359
- Peptide Label: isoform X4
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037350 Ensembl, UniProtKB/TrEMBL
  ENSPPAG00050035827 ENTREZGENE
Ensembl Transcript ENSPPAT00000051467.1 UniProtKB/TrEMBL
  ENSPPAT00050076581 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Myelin-PO_C UniProtKB/TrEMBL
  Myelin_P0-rel UniProtKB/TrEMBL
  Myelin_P0_CS UniProtKB/TrEMBL
  Myelin_P0_Ig-like UniProtKB/TrEMBL
NCBI Gene MPZ ENTREZGENE
PANTHER PTHR13869 UniProtKB/TrEMBL
  PTHR13869:SF7 UniProtKB/TrEMBL
Pfam Myelin-PO_C UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PRINTS MYELINP0 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  MYELIN_P0 UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9BG50 ENTREZGENE, UniProtKB/TrEMBL