MPZ (myelin protein zero) - Rat Genome Database

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Gene: MPZ (myelin protein zero) Pan paniscus
Analyze
Symbol: MPZ
Name: myelin protein zero
RGD ID: 11861635
Description: INVOLVED IN cell-cell junction maintenance (ortholog); myelination (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH atrophic muscular disease (ortholog); autoimmune interstitial lung, joint, and kidney disease (ortholog); autosomal dominant distal hereditary motor neuronopathy 14 (ortholog); FOUND IN basolateral plasma membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: myelin protein P0
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,543,449 - 88,573,944 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,233,764 - 88,264,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,691,245 - 136,720,958 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,603,609 - 140,631,273 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,626,039 - 140,631,273 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MPZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,543,449 - 88,573,944 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,233,764 - 88,264,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,691,245 - 136,720,958 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,603,609 - 140,631,273 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,626,039 - 140,631,273 (-)Ensemblpanpan1.1panPan2
MPZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,303,600 - 161,309,968 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,304,735 - 161,309,968 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,274,525 - 161,279,758 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,541,151 - 159,546,377 (-)NCBINCBI36Build 36hg18NCBI36
Build 341158,087,599 - 158,092,817NCBI
Celera1134,341,666 - 134,346,903 (-)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,631,395 - 132,636,601 (-)NCBIHuRef
CHM1_11162,670,753 - 162,675,990 (-)NCBICHM1_1
T2T-CHM13v2.01160,441,004 - 160,447,413 (-)NCBIT2T-CHM13v2.0
Mpz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,978,282 - 170,988,699 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,978,280 - 170,988,699 (+)EnsemblGRCm39 Ensembl
GRCm381171,150,713 - 171,161,130 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,150,711 - 171,161,130 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,080,844 - 173,091,254 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,987,388 - 172,997,798 (+)NCBIMGSCv36mm8
Celera1173,598,959 - 173,609,357 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.05NCBI
Mpz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,103,290 - 86,109,156 (+)NCBIGRCr8
mRatBN7.21383,570,811 - 83,576,680 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,570,811 - 83,576,679 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,076,519 - 86,082,418 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,474,755 - 87,480,657 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,706,501 - 84,712,211 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,524,204 - 89,530,070 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,524,329 - 89,530,068 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,151,850 - 94,156,749 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,040,479 - 87,045,378 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,229,362 - 87,234,262 (+)NCBI
Celera1383,202,202 - 83,207,991 (+)NCBICelera
Cytogenetic Map13q24NCBI
Mpz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546813,041,011 - 13,047,284 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546813,041,911 - 13,047,026 (-)NCBIChiLan1.0ChiLan1.0
MPZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,205,339 - 21,210,439 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,205,107 - 21,210,451 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,280,251 - 21,285,323 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,323,207 - 21,328,277 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,323,098 - 21,328,270 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,220,355 - 21,225,416 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,626,466 - 21,631,518 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,034,738 - 22,039,792 (+)NCBIUU_Cfam_GSD_1.0
Mpz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,375,284 - 7,380,521 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903583,942 - 589,160 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903583,942 - 589,160 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,169,311 - 89,179,925 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,174,107 - 89,179,556 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,031,478 - 97,036,934 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,662,163 - 2,668,393 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,665,737 - 2,668,393 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,720,210 - 1,725,435 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794100,824 - 106,444 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794101,095 - 106,508 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000051467   ⟹   ENSPPAP00000028619
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1140,626,039 - 140,631,273 (-)Ensembl
RefSeq Acc Id: XM_003811824   ⟹   XP_003811872
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,462 - 88,551,845 (+)NCBI
NHGRI_mPanPan1188,233,773 - 88,251,725 (+)NCBI
Mhudiblu_PPA_v01136,712,500 - 136,720,945 (-)NCBI
PanPan1.11140,626,039 - 140,631,273 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034939019   ⟹   XP_034794910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,456 - 88,551,845 (+)NCBI
NHGRI_mPanPan1188,233,769 - 88,239,405 (+)NCBI
Mhudiblu_PPA_v01136,715,333 - 136,720,953 (-)NCBI
RefSeq Acc Id: XM_055112352   ⟹   XP_054968327
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,449 - 88,573,944 (+)NCBI
NHGRI_mPanPan1188,233,764 - 88,264,228 (+)NCBI
RefSeq Acc Id: XM_055112355   ⟹   XP_054968330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,450 - 88,573,944 (+)NCBI
NHGRI_mPanPan1188,233,765 - 88,264,228 (+)NCBI
RefSeq Acc Id: XM_055112359   ⟹   XP_054968334
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,449 - 88,562,675 (+)NCBI
NHGRI_mPanPan1188,233,765 - 88,252,963 (+)NCBI
RefSeq Acc Id: XR_004666573
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,451 - 88,573,944 (+)NCBI
NHGRI_mPanPan1188,233,766 - 88,264,228 (+)NCBI
Mhudiblu_PPA_v01136,691,245 - 136,720,958 (-)NCBI
RefSeq Acc Id: XR_010112120
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,449 - 88,564,383 (+)NCBI
RefSeq Acc Id: XR_010112121
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,543,451 - 88,571,556 (+)NCBI
RefSeq Acc Id: XP_003811872   ⟸   XM_003811824
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BG50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034794910   ⟸   XM_034939019
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000028619   ⟸   ENSPPAT00000051467
RefSeq Acc Id: XP_054968327   ⟸   XM_055112352
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054968330   ⟸   XM_055112355
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054968334   ⟸   XM_055112359
- Peptide Label: isoform X4
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037350 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051467.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Myelin-PO_C UniProtKB/TrEMBL
  Myelin_P0-rel UniProtKB/TrEMBL
  Myelin_P0_CS UniProtKB/TrEMBL
  Myelin_P0_Ig-like UniProtKB/TrEMBL
NCBI Gene MPZ ENTREZGENE
PANTHER PTHR13869 UniProtKB/TrEMBL
  PTHR13869:SF7 UniProtKB/TrEMBL
Pfam Myelin-PO_C UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PRINTS MYELINP0 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  MYELIN_P0 UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9BG50 ENTREZGENE, UniProtKB/TrEMBL