IGF2R (insulin like growth factor 2 receptor) - Rat Genome Database

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Gene: IGF2R (insulin like growth factor 2 receptor) Pan paniscus
Analyze
Symbol: IGF2R
Name: insulin like growth factor 2 receptor
RGD ID: 11729625
Description: ENCODES a protein that exhibits enzyme binding (ortholog); G-protein alpha-subunit binding (ortholog); insulin-like growth factor II binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); G protein-coupled receptor signaling pathway (ortholog); liver development (ortholog); PARTICIPATES IN renin-angiotensin cascade pathway; ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN clathrin coat (ortholog); endosome (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cation-independent mannose-6-phosphate receptor; cation-independent mannose-6-phosphate receptor-like; LOC112440068
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25180,068,746 - 180,206,598 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,973,023 - 178,110,866 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,852,565 - 157,990,049 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,884,786 - 162,983,968 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,878,661 - 162,997,762 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
IGF2R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25180,068,746 - 180,206,598 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,973,023 - 178,110,866 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,852,565 - 157,990,049 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,884,786 - 162,983,968 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,878,661 - 162,997,762 (+)Ensemblpanpan1.1panPan2
IGF2R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386159,969,082 - 160,111,504 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6159,969,082 - 160,113,507 (+)EnsemblGRCh38hg38GRCh38
GRCh376160,390,114 - 160,532,536 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,310,121 - 160,447,573 (+)NCBINCBI36Build 36hg18NCBI36
Build 346160,360,541 - 160,497,992NCBI
Celera6161,035,974 - 161,173,355 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6157,860,740 - 157,998,270 (+)NCBIHuRef
CHM1_16160,652,348 - 160,789,828 (+)NCBICHM1_1
T2T-CHM13v2.06161,215,266 - 161,357,599 (+)NCBIT2T-CHM13v2.0
Igf2r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,901,293 - 12,988,593 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1712,901,293 - 12,988,551 (-)EnsemblGRCm39 Ensembl
GRCm381712,682,406 - 12,769,706 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,682,406 - 12,769,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,875,272 - 12,962,572 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,525,771 - 12,613,022 (-)NCBIMGSCv36mm8
Celera1712,714,412 - 12,801,753 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.64NCBI
Igf2r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,526,878 - 50,615,265 (+)NCBIGRCr8
mRatBN7.2147,979,109 - 48,067,501 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,979,109 - 48,067,501 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,670,745 - 48,759,134 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,656,245 - 54,744,657 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,746,270 - 48,834,659 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,176,095 - 48,264,482 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,176,106 - 48,264,477 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,488,767 - 51,577,141 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,253,273 - 42,341,646 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,256,217 - 42,344,589 (+)NCBI
Celera143,778,518 - 43,867,238 (+)NCBICelera
Cytogenetic Map1q11NCBI
Igf2r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543920,752,855 - 20,851,281 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543920,754,915 - 20,874,759 (-)NCBIChiLan1.0ChiLan1.0
IGF2R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,161,551 - 49,262,260 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,161,444 - 49,262,277 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,002,759 - 50,102,366 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,345,406 - 49,445,163 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,345,406 - 49,445,163 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,227,935 - 49,327,529 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0149,099,537 - 49,199,165 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,714,384 - 49,814,084 (+)NCBIUU_Cfam_GSD_1.0
Igf2r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,195,094 - 144,271,698 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,447,038 - 11,524,174 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,447,043 - 11,523,695 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGF2R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,368,103 - 7,472,548 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,369,485 - 7,472,480 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,168,321 - 9,271,328 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGF2R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,587,717 - 87,723,795 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1387,587,907 - 87,724,116 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604059,978,473 - 60,111,795 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igf2r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248552,753,994 - 2,887,151 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248552,752,676 - 2,887,327 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000024347   ⟹   ENSPPAP00000005362
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6162,878,661 - 162,997,762 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000024376   ⟹   ENSPPAP00000005368
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6162,878,661 - 162,990,732 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000024406   ⟹   ENSPPAP00000005380
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6162,881,192 - 162,997,762 (+)Ensembl
RefSeq Acc Id: XM_034963192   ⟹   XP_034819083
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25180,068,746 - 180,206,598 (+)NCBI
NHGRI_mPanPan16177,973,023 - 178,110,866 (+)NCBI
Mhudiblu_PPA_v06157,852,565 - 157,990,049 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034819083 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005362.1
  ENSPPAP00000005368.1
  ENSPPAP00000005380.1
Reference Protein Sequences
RefSeq Acc Id: XP_034819083   ⟸   XM_034963192
- UniProtKB: A0A2R8ZN36 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000005362   ⟸   ENSPPAT00000024347
RefSeq Acc Id: ENSPPAP00000005368   ⟸   ENSPPAT00000024376
RefSeq Acc Id: ENSPPAP00000005380   ⟸   ENSPPAT00000024406
Protein Domains
Fibronectin type-II   MRH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000022058 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000024347.1 UniProtKB/TrEMBL
  ENSPPAT00000024376.1 UniProtKB/TrEMBL
  ENSPPAT00000024406.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.10.10 UniProtKB/TrEMBL
  2.70.130.10 UniProtKB/TrEMBL
InterPro CIMR_rpt UniProtKB/TrEMBL
  FN_type2_dom UniProtKB/TrEMBL
  FN_type2_sf UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Man6P_isomerase_rcpt-bd_dom_sf UniProtKB/TrEMBL
  MRH_dom UniProtKB/TrEMBL
NCBI Gene IGF2R ENTREZGENE
PANTHER MANNOSE 6-PHOSPHATE RECEPTOR-LIKE PROTEIN 1 UniProtKB/TrEMBL
  MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER UniProtKB/TrEMBL
Pfam CIMR UniProtKB/TrEMBL
  fn2 UniProtKB/TrEMBL
PRINTS FNTYPEII UniProtKB/TrEMBL
PROSITE FN2_1 UniProtKB/TrEMBL
  FN2_2 UniProtKB/TrEMBL
  MRH UniProtKB/TrEMBL
SMART CIMR UniProtKB/TrEMBL
  FN2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50911 UniProtKB/TrEMBL
  SSF57440 UniProtKB/TrEMBL
UniProt A0A2R8ZK70_PANPA UniProtKB/TrEMBL
  A0A2R8ZK72_PANPA UniProtKB/TrEMBL
  A0A2R8ZN36 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-11 IGF2R  insulin like growth factor 2 receptor  LOC112440068  cation-independent mannose-6-phosphate receptor-like  Data merged from RGD:13587181 737654 PROVISIONAL