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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:diabetic encephalopathy
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Accession:DOID:0050850 term browser browse the term
Definition:A brain disease that is characterized by functional impairment of cognition, cerebral signal conduction, neurotransmission and synaptic plasticity, and underlying structural pathology associated with diabetes. (DO)
Synonyms:exact_synonym: diabetic encephalopathies


show annotations for term's descendants           Sort by:
diabetic encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23529380 PMID:24291733 RGD:7244255, RGD:8553040 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G App amyloid beta precursor protein treatment IEP associated with type 2 diabetes mellitus RGD PMID:28885995 RGD:13782056 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP associated with Diabetes Mellitus, Experimental RGD PMID:17601561 RGD:7771546 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:26970304 RGD:13792771 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Ide insulin degrading enzyme ISO associated with type 2 diabetes mellitus RGD PMID:27306699 RGD:13792796 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440 		JBrowse link
G Ngf nerve growth factor treatment ISO associated with Diabetes Mellitus, Experimental
associated with Experimental Diabetes Mellitus		 RGD PMID:23528019 PMID:32681844 RGD:7242845, RGD:402463968 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:24291733 RGD:8553040 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19065
    disease of anatomical entity 18355
      endocrine system disease 6863
        diabetes mellitus 1662
          Diabetes Complications 540
            diabetic encephalopathy 8
Path 2
Term Annotations click to browse term
  disease 19065
    Developmental Disease 14582
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 13621
        genetic disease 13292
          inherited metabolic disorder 6601
            carbohydrate metabolic disorder 3412
              glucose metabolism disease 2158
                diabetes mellitus 1662
                  Diabetes Complications 540
                    diabetic encephalopathy 8
paths to the root