EPHX2 (epoxide hydrolase 2) - Rat Genome Database

Name: EPHX2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: EPHX2 (epoxide hydrolase 2) Pan paniscus

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Symbol:

EPHX2

Name:

epoxide hydrolase 2

RGD ID:

12023421

Description:

ENCODES a protein that exhibits epoxide hydrolase activity (ortholog); magnesium ion binding (ortholog); phosphatase activity (ortholog); INVOLVED IN dephosphorylation (ortholog); linoleic acid metabolic process (ortholog); positive regulation of blood pressure (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); atherosclerosis (ortholog); FOUND IN peroxisome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

bifunctional epoxide hydrolase 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EPHX2 (epoxide hydrolase 2)	NCBI	Ortholog
Mus musculus (house mouse):	Ephx2 (epoxide hydrolase 2, cytoplasmic)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ephx2 (epoxide hydrolase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ephx2 (epoxide hydrolase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EPHX2 (epoxide hydrolase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ephx2 (epoxide hydrolase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EPHX2 (epoxide hydrolase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EPHX2 (epoxide hydrolase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ephx2 (epoxide hydrolase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	46,021,291 - 46,079,005 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	21,735,517 - 21,793,206 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	26,761,090 - 26,818,436 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	23,964,094 - 24,017,749 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	23,964,094 - 24,017,749 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

Acute Lung Injury (ISO)

atherosclerosis (ISO)

autism spectrum disorder (ISO)

autosomal dominant nocturnal frontal lobe epilepsy (ISO)

benign familial infantile seizures 6 (ISO)

Brain Injuries (ISO)

cardiac arrest (ISO)

cerebral infarction (ISO)

congestive heart failure (ISO)

coronary artery disease (ISO)

Coronary Disease (ISO)

Diabetic Nephropathies (ISO)

end stage renal disease (ISO)

Endotoxemia (ISO)

familial hypercholesterolemia (ISO)

Hyperalgesia (ISO)

hypertension (ISO)

hypertrophic cardiomyopathy (ISO)

Metabolic Syndrome (ISO)

myocardial infarction (ISO)

Myocardial Ischemia (ISO)

Myocardial Reperfusion Injury (ISO)

Parkinson's disease (ISO)

Plaque, Atherosclerotic (ISO)

pulmonary hypertension (ISO)

Reperfusion Injury (ISO)

schizophrenia (ISO)

Stroke (ISO)

Ventricular Dysfunction, Left (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cholesterol homeostasis (IEA)

dephosphorylation (ISO)

epoxide metabolic process (IEA)

linoleic acid metabolic process (ISO)

phospholipid dephosphorylation (IEA)

positive regulation of blood pressure (ISO)

positive regulation of gene expression (IEA)

prostaglandin production involved in inflammatory response (ISO)

regulation of cholesterol metabolic process (IEA)

response to 3-methylcholanthrene (ISO)

stilbene catabolic process (IEA)

Cellular Component

cytosol (IEA)

peroxisome (IEA,ISO)

Molecular Function

catalytic activity (IEA)

epoxide hydrolase activity (IEA,ISO)

hydrolase activity (IEA)

lipid phosphatase activity (IEA)

lysophosphatidic acid phosphatase activity (IEA)

magnesium ion binding (IEA,ISO)

phosphatase activity (IEA,ISO)

protein homodimerization activity (IEA)

toxic substance binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylsalicylic acid pharmacodynamics pathway (ISO)

antipyrine drug pathway (ISO)

arachidonic acid metabolic pathway (ISO)

celecoxib pharmacodynamics pathway (ISO)

diclofenac pharmacodynamics pathway (ISO)

diflunisal pharmacodynamics pathway (ISO)

etodolac pharmacodynamics pathway (ISO)

fenoprofen pharmacodynamics pathway (ISO)

flurbiprofen pharmacodynamics pathway (ISO)

ibuprofen pharmacodynamics pathway (ISO)

indometacin pharmacodynamics pathway (ISO)

ketoprofen pharmacodynamics pathway (ISO)

ketorolac pharmacodynamics pathway (ISO)

leukotriene C4 synthase deficiency pathway (ISO)

lornoxicam pharmacodynamics pathway (ISO)

magnesium salicylate pharmacodynamics pathway (ISO)

mefenamic acid pharmacodynamics pathway (ISO)

meloxicam pharmacodynamics pathway (ISO)

nabumetone pharmacodynamics pathway (ISO)

naproxen pharmacodynamics pathway (ISO)

paracetamol drug pathway (ISO)

piroxicam pharmacodynamics pathway (ISO)

salicylic acid pharmacodynamics pathway (ISO)

sodium salicylate pharmacodynamics pathway (ISO)

sulindac pharmacodynamics pathway (ISO)

tenoxicam pharmacodynamics pathway (ISO)

tiaprofenic acid pharmacodynamics pathway (ISO)

tolmetin pharmacodynamics pathway (ISO)

valdecoxib pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

EPHX2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	46,021,291 - 46,079,005 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	21,735,517 - 21,793,206 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	26,761,090 - 26,818,436 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	23,964,094 - 24,017,749 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	23,964,094 - 24,017,749 (+)	Ensembl	panpan1.1		panPan2

EPHX2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	27,491,143 - 27,548,626 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	27,490,781 - 27,545,564 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	27,348,660 - 27,406,143 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	27,404,562 - 27,458,403 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	27,404,561 - 27,458,403	NCBI
Celera	8	26,308,750 - 26,362,585 (+)	NCBI		Celera
Cytogenetic Map	8	p21.2-p21.1	NCBI
HuRef	8	25,893,566 - 25,947,482 (+)	NCBI		HuRef
CHM1_1	8	27,550,382 - 27,604,304 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	27,768,490 - 27,825,967 (+)	NCBI		T2T-CHM13v2.0

Ephx2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	66,321,821 - 66,361,971 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	66,321,823 - 66,361,949 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	66,084,372 - 66,124,522 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	66,084,374 - 66,124,500 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	66,703,214 - 66,743,337 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	65,038,487 - 65,078,610 (-)	NCBI		MGSCv36	mm8
Celera	14	63,832,362 - 63,872,496 (-)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	34.36	NCBI

Ephx2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	44,465,447 - 44,503,157 (-)	NCBI		GRCr8
mRatBN7.2	15	40,289,901 - 40,327,632 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	40,289,902 - 40,327,615 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	42,154,869 - 42,194,845 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	43,305,067 - 43,345,042 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	41,750,237 - 41,787,912 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	42,757,241 - 42,794,211 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	42,757,235 - 42,794,279 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	48,799,823 - 48,836,848 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	45,497,660 - 45,556,101 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	45,513,439 - 45,571,881 (-)	NCBI
Celera	15	39,961,087 - 40,000,936 (-)	NCBI		Celera
Cytogenetic Map	15	p12	NCBI

Ephx2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	49,999,563 - 50,041,572 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	49,999,563 - 50,038,800 (+)	NCBI	ChiLan1.0	ChiLan1.0

EPHX2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	30,045,040 - 30,107,110 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	30,045,291 - 30,107,110 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	30,631,771 - 30,693,869 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	30,235,290 - 30,297,630 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	30,232,724 - 30,297,642 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	30,165,721 - 30,227,963 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	30,046,546 - 30,108,832 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	30,212,901 - 30,275,213 (-)	NCBI		UU_Cfam_GSD_1.0

Ephx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	8,193,232 - 8,235,694 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936675	350,342 - 392,551 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936675	350,357 - 392,919 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EPHX2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	11,216,978 - 11,293,410 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	11,217,125 - 11,293,018 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	12,397,646 - 12,473,595 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EPHX2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	25,603,668 - 25,659,232 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	25,603,735 - 25,659,345 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	16,482,843 - 16,540,761 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ephx2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	22,221,314 - 22,254,813 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	22,216,462 - 22,252,467 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003830799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008956234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034965877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055116385	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000045366 ⟹ ENSPPAP00000022555

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	8	23,964,094 - 24,017,749 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000045381 ⟹ ENSPPAP00000022570

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	8	23,964,094 - 24,017,748 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000045397 ⟹ ENSPPAP00000022586

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	8	23,964,301 - 24,017,348 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000045403 ⟹ ENSPPAP00000022592

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	8	23,974,106 - 24,017,348 (+)	Ensembl

RefSeq Acc Id:

XM_003830799 ⟹ XP_003830847

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	46,021,291 - 46,075,287 (+)	NCBI
NHGRI_mPanPan1	8	21,735,517 - 21,789,502 (+)	NCBI
Mhudiblu_PPA_v0	8	26,761,091 - 26,814,786 (+)	NCBI
PanPan1.1	8	23,964,094 - 24,017,749 (+)	NCBI

Sequence:

show sequence

GTGCCCCTCCCCCTGCCTCTTTCCCGGCCAGAGTCCAGCCTTAACCCGGGCAGGGGGCGGAGTC
CCGTTAAGGCGGTGTGGGGAGGAGGCGGGGCCAGGGCAGGGGCGGGGTAGAGCCGGGCCAAGCT
GGGCGGGTCATGCGCCCTGGCCTTCGCGCATCTCCCAGGTTAGCTGCGTGTCCGGGTGCTAGGC
TGCAGACCCGCCGCCATGACGCTGCGCGCGGCCGTCTTCGACCTTGACGGGGTGCTGGCGCTGC
CAGCGGTGTTCGGCGTCCTCGGCCGCACGGAGGAGGCCCTGGCGCTGCCCAGAGGACTTCTGAA
TGATGCTTTCCAGAAAGGGGGACCAGAGGGTGCCACTACCCGGCTTATGAGAGGAGAGATCACA
CTTTCCCAGTGGATACCACTCATGGAAGAAAACTGCAGGAAGTGCTCCGAGACCGCTAAAGTCT
GCCTCCCCAAGAATTTCTCCGTAAAAGAAATCTTTGACAAGGCGATTTCAGCCAGAAAGATCAA
CCGCCCCATGCTCCAGGCAGCTGTCATGCTCAGGAAGAAAGGATTCACAACTGCCATCCTCACC
AACACCTGGCTGGACGACCGTGCTGAGAGAGATGGCCTGGCCCAGCTGATGTGTGAGCTGAAGA
TGCACTTTGACTTCCTGATAGAGTCGTGTCAGGTGGGAATGGTCAAACCTGAACCTCAGATCTA
CAAGTTTCTGCTGGACACCCTGAAGGCCAGCCCCAGTGAGGTCGTTTTTTTGGATGACATCGGG
GCTAATCTGAAGCCAGCCCGTGACTTGGGAATGGTCACCATCCTGGTCCAGGACACTGACACGG
CCCTGAAAGAACTGGAGAAAGTGACCGGAATCCAGCTTCTCAATACCCCAGCCCCTCTGCCGAC
CTCTTGCAATCCAAGTGACATGAGCCATGGGTACGTGACAGTAAAGCCCGGGGTCCGTCTGCAT
TTTGTGGAGCTGGGCTCCGGCCCTGCTGTGTGCCTCTGCCATGGATTTCCCGAGAGCTGGTATT
CTTGGAGGTACCAGATCCCTGCTCTGGCCCAGGCAGGTTACCGGGTCCTAGCTATGGACATGAA
AGGCTATGGAGAGTCATCTGCTCCTCCCGAAATAGAAGAATATTGCATGGAAGTGTTATGTAAG
GAGATGGTAACCTTCCTGGATAAACTGGGCCTCTCTCAAGCAGTGTTCATTGGCCATGACTGGG
GTGGCATGCTGGTGTGGTACATGGCTCTCTTCTACCCCGAGAGAGTGAGGGCGGTGGCCAGTTT
GAATACTCCCTTCATACCAGCAAATCCCAACGTGTCCCCTTTGGAGAGTATCAAAGCCAACCCA
GTATTTGATTACCAGCTCTACTTCCAGGAACCAGGAGTGGCTGAGGCTGAACTGGAACAGAACC
TGAGTCGGACTTTCAAAAGCCTCTTCAGAGCAAGCGATGAGAGTGTTTTATCCATGCATAAAGT
CTGTGAAGCGGGAGGACTTTTTGTAAATAGCCCAGAAGAGCCCAGCCTCAGCAGGATGGTCACT
GAGGAGGAAATCCAGTTCTATGTGCAGCAGTTCAAGAAGTCTGGTTTCAGAGGTCCTCTAAACT
GGTACCGAAACATGGAAAGGAACTGGAAGTGGGCCTGCAAAAGCTTGGGACGGAAGATCCTGAT
TCCGGCCCTGATGGTCACGGCGGAAAAGGACTTCGTGCTCGTTCCTCAGATGTCCAAGCACATG
GAGGACTGGATTCCCCACCTGAAAAGGGGACACATTGAGGACTGTGGGCACTGGACACAGATGG
ACAAGCCCACCGAGGTGAATCAGATCCTCATTAAGTGGCTGGATTCTGATGCCCGGAACCCACC
GGTGGTCTCAAAGATGTAGAACGCAGCGTGCGCCCACGCTCAGCAGGTGTGCCTTGCTTCCACC
TGCTGGGGCACCATTCTTAGTATACAGAGGTGGCCTTACACACATCTCACATGGATGGCAGCAT
TGTTCTGAAGGGGTTTGCAGAAAAAAAAAGATTTTCTTTACATAAAGTGAGTCAAATTTGACAT
TATTTTAGATCCCAGAGAAATCAGGTGTGATTAGTTCTCCAGGCATGAATGCATCGTCCCTTTA
TCTGTAAGAACCCTTAGTGTCCTGTAGGGGGACAGAATGGGGTGGCCAGGTGGTGATTTCTCTT
TGACCAATGCATAGTTTGGCAGAAAAATCAGCCGTTCATTTAGAAGAATCTTAGTAGAGATTGG
AATGCCTTACTCAATAAAGCTAAGATGACTATGCTG

hide sequence

RefSeq Acc Id:

XM_008956234 ⟹ XP_008954482

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	46,021,571 - 46,075,287 (+)	NCBI
NHGRI_mPanPan1	8	21,735,802 - 21,789,502 (+)	NCBI
Mhudiblu_PPA_v0	8	26,761,090 - 26,814,786 (+)	NCBI
PanPan1.1	8	23,964,094 - 24,017,748 (+)	NCBI

Sequence:

show sequence

GTGCCCCTCCCCCTGCCTCTTTCCCGGCCAGAGTCCAGCCTTAACCCGGGCAGGGGGCGGAGTC
CCGTTAAGGCGGTGTGGGGAGGAGGCGGGGCCAGGGCAGGGGCGGGGTAGAGCCGGGCCAAGCT
GGGCGGGTCATGCGCCCTGGCCTTCGCGCATCTCCCAGGTTAGCTGCGTGTCCGGGTGCTAGGC
TGCAGACCCGCCGCCATGACGCTGCGCGCGGCCGTCTTCGACCTTGACGGGGTGCTGGCGCTGC
CAGCGGTGTTCGGCGTCCTCGGCCGCACGGAGGAGGCCCTGGCGCTGCCCAGAGGACTTCTGAA
TGATGCTTTCCAGAAAGGGGGACCAGAGGGTGCCACTACCCGGCTTATGAGAGGAGAGATCACA
CTTTCCCAGTGGATACCACTCATGGAAGAAAACTGCAGGAAGTGCTCCGAGACCGCTAAAGTCT
GCCTCCCCAAGAATTTCTCCGTAAAAGAAATCTTTGACAAGGCGATTTCAGCCAGAAAGATCAA
CCGCCCCATGCTCCAGGCAGCTGTCATGCTCAGGAAGAAAGGATTCACAACTGCCATCCTCACC
AACACCTGGCTGGACGACCGTGCTGAGAGAGATGGCCTGGCCCAGCTGATGTGTGAGCTGAAGA
TGCACTTTGACTTCCTGATAGAGTCGTGTCAGGTGGGAATGGTCAAACCTGAACCTCAGATCTA
CAAGTTTCTGCTGGACACCCTGAAGGCCAGCCCCAGTGAGGTCGTTTTTTTGGATGACATCGGG
GCTAATCTGAAGCCAGCCCGTGACTTGGGAATGGTCACCATCCTGGTCCAGGACACTGACACGG
CCCTGAAAGAACTGGAGAAAGTGACCGGAATCCAGCTTCTCAATACCCCAGCCCCTCTGCCGAC
CTCTTGCAATCCAAGTGACATGAGCCATGGGTACGTGACAGTAAAGATCCCTGCTCTGGCCCAG
GCAGGTTACCGGGTCCTAGCTATGGACATGAAAGGCTATGGAGAGTCATCTGCTCCTCCCGAAA
TAGAAGAATATTGCATGGAAGTGTTATGTAAGGAGATGGTAACCTTCCTGGATAAACTGGGCCT
CTCTCAAGCAGTGTTCATTGGCCATGACTGGGGTGGCATGCTGGTGTGGTACATGGCTCTCTTC
TACCCCGAGAGAGTGAGGGCGGTGGCCAGTTTGAATACTCCCTTCATACCAGCAAATCCCAACG
TGTCCCCTTTGGAGAGTATCAAAGCCAACCCAGTATTTGATTACCAGCTCTACTTCCAGGAACC
AGGAGTGGCTGAGGCTGAACTGGAACAGAACCTGAGTCGGACTTTCAAAAGCCTCTTCAGAGCA
AGCGATGAGAGTGTTTTATCCATGCATAAAGTCTGTGAAGCGGGAGGACTTTTTGTAAATAGCC
CAGAAGAGCCCAGCCTCAGCAGGATGGTCACTGAGGAGGAAATCCAGTTCTATGTGCAGCAGTT
CAAGAAGTCTGGTTTCAGAGGTCCTCTAAACTGGTACCGAAACATGGAAAGGAACTGGAAGTGG
GCCTGCAAAAGCTTGGGACGGAAGATCCTGATTCCGGCCCTGATGGTCACGGCGGAAAAGGACT
TCGTGCTCGTTCCTCAGATGTCCAAGCACATGGAGGACTGGATTCCCCACCTGAAAAGGGGACA
CATTGAGGACTGTGGGCACTGGACACAGATGGACAAGCCCACCGAGGTGAATCAGATCCTCATT
AAGTGGCTGGATTCTGATGCCCGGAACCCACCGGTGGTCTCAAAGATGTAGAACGCAGCGTGCG
CCCACGCTCAGCAGGTGTGCCTTGCTTCCACCTGCTGGGGCACCATTCTTAGTATACAGAGGTG
GCCTTACACACATCTCACATGGATGGCAGCATTGTTCTGAAGGGGTTTGCAGAAAAAAAAAGAT
TTTCTTTACATAAAGTGAGTCAAATTTGACATTATTTTAGATCCCAGAGAAATCAGGTGTGATT
AGTTCTCCAGGCATGAATGCATCGTCCCTTTATCTGTAAGAACCCTTAGTGTCCTGTAGGGGGA
CAGAATGGGGTGGCCAGGTGGTGATTTCTCTTTGACCAATGCATAGTTTGGCAGAAAAATCAGC
CGTTCATTTAGAAGAATCTTAGTAGAGATTGGAATGCCTTACTCAATAAAGCTAAGATGACTAT
GCT

hide sequence

RefSeq Acc Id:

XM_034965877 ⟹ XP_034821768

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	46,021,554 - 46,079,005 (+)	NCBI
NHGRI_mPanPan1	8	21,735,777 - 21,793,206 (+)	NCBI
Mhudiblu_PPA_v0	8	26,761,127 - 26,818,436 (+)	NCBI

RefSeq Acc Id:

XM_055116385 ⟹ XP_054972360

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	46,021,564 - 46,041,809 (+)	NCBI
NHGRI_mPanPan1	8	21,735,801 - 21,756,018 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003830847	(Get FASTA)	NCBI Sequence Viewer
	XP_008954482	(Get FASTA)	NCBI Sequence Viewer
	XP_034821768	(Get FASTA)	NCBI Sequence Viewer
	XP_054972360	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000022555.1
	ENSPPAP00000022570.1
	ENSPPAP00000022586.1
	ENSPPAP00000022592.1

RefSeq Acc Id:	XP_003830847 ⟸ XM_003830799
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AZ97 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITLSQWI PLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAAVMLRKKGFTTAILTNTWLD DRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKP ARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPGVRLHFVELG SGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTF LDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNVSPLESIKANPVFDYQ LYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQ FYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIP HLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM hide sequence

RefSeq Acc Id:	XP_008954482 ⟸ XM_008956234
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9AZB4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITLSQWI PLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAAVMLRKKGFTTAILTNTWLD DRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKP ARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKIPALAQAGYRV LAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERV RAVASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESV LSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDS DARNPPVVSKM hide sequence

RefSeq Acc Id:	XP_034821768 ⟸ XM_034965877
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSPPAP00000022555 ⟸ ENSPPAT00000045366

Ensembl Acc Id:

ENSPPAP00000022570 ⟸ ENSPPAT00000045381

Ensembl Acc Id:

ENSPPAP00000022586 ⟸ ENSPPAT00000045397

Ensembl Acc Id:

ENSPPAP00000022592 ⟸ ENSPPAT00000045403

RefSeq Acc Id:	XP_054972360 ⟸ XM_055116385
- Peptide Label:	isoform X4

Protein Domains

AB hydrolase-1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034443	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000045366.1	UniProtKB/TrEMBL
	ENSPPAT00000045381.1	UniProtKB/TrEMBL
	ENSPPAT00000045397.1	UniProtKB/TrEMBL
	ENSPPAT00000045403.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1000	UniProtKB/TrEMBL
	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	AB_hydrolase_1	UniProtKB/TrEMBL
	Epox_hydrolase-like	UniProtKB/TrEMBL
	HAD-like_sf	UniProtKB/TrEMBL
	HAD-SF_hydro_IA	UniProtKB/TrEMBL
	HAD-SF_ppase_IA/epoxid_hydro_N	UniProtKB/TrEMBL
	HAD_sf	UniProtKB/TrEMBL
	PGP-like_dom2	UniProtKB/TrEMBL
KEGG Report	pps:100990932	UniProtKB/TrEMBL
NCBI Gene	EPHX2	ENTREZGENE
PANTHER	BIFUNCTIONAL EPOXIDE HYDROLASE 2	UniProtKB/TrEMBL
	EPOXIDE HYDROLASE	UniProtKB/TrEMBL
Pfam	Abhydrolase_1	UniProtKB/TrEMBL
	Hydrolase	UniProtKB/TrEMBL
PRINTS	ABHYDROLASE	UniProtKB/TrEMBL
	EPOXHYDRLASE	UniProtKB/TrEMBL
	HADHALOGNASE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
	SSF56784	UniProtKB/TrEMBL
UniProt	A0A2R9AZ97	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AZB4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B351_PANPA	UniProtKB/TrEMBL
	A0A2R9B5B7_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB