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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:diabetes mellitus
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Accession:DOID:9351 term browser browse the term
Definition:A glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)
Synonyms:narrow_synonym: monogenic diabetes;   transient neonatal diabetes
 primary_id: MESH:D003920
 xref: ICD10CM:E08-E13;   ICD9CM:250;   NCI:C2985
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
diabetes mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Neonatal diabetes mellitus
ClinVar PMID:9618169 PMID:9648840 PMID:10204114 PMID:14692646 PMID:14715863 PMID:14764815 PMID:15562009 PMID:16357843 PMID:16885549 PMID:17236890 PMID:17389331 PMID:17446535 PMID:18025464 PMID:18346985 PMID:18414213 PMID:18599530 PMID:19342262 PMID:20685672 PMID:20799350 PMID:20943781 PMID:21378087 PMID:21989597 PMID:22210575 PMID:22562119 PMID:22855730 PMID:23093687 PMID:23226049 PMID:23275527 PMID:23771920 PMID:24622368 PMID:24768178 PMID:24814349 PMID:25306193 PMID:25525159 PMID:25555642 PMID:25741868 PMID:26467025 PMID:26839896 PMID:27271189 PMID:28095440 PMID:28346775 PMID:28492532 PMID:29207974 PMID:29216354 PMID:30311386, PMID:16416420 RGD:1625279 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 IEP protein:increased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acp1 acid phosphatase 1 ISO RGD PMID:8620937 RGD:2313188 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18378355 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:23396398 RGD:7243186 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22831748 PMID:25741868 PMID:26336158 PMID:28492532 NCBI chr 3:4,044,741...4,055,384
Ensembl chr 3:4,044,542...4,055,806
JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO mRNA:reduced expression:pancreatic islet (mouse) RGD PMID:11904435 RGD:2313440 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18154657 PMID:21943378 PMID:22876109 PMID:24033266 PMID:25533962 PMID:25741868 PMID:25846608 PMID:26104972 PMID:26239645 PMID:26467025 PMID:26636822 PMID:27178444 PMID:28492532 PMID:28502102 PMID:28717663 PMID:29610177 NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
JBrowse link
G Alpk1 alpha-kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 2:231,997,360...232,117,471
Ensembl chr 2:231,996,088...232,117,134
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apob apolipoprotein B ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc2 apolipoprotein C2 ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Apoc3 apolipoprotein C3 ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E treatment ISO RGD PMID:17192461 RGD:1601230 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apoh apolipoprotein H ISO protein:increased expression:plasma
mRNA:increased expression:retina
RGD PMID:9377806, PMID:18695102 RGD:2313991, RGD:2313982 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Aqp1 aquaporin 1 IEP protein:altered localization:retina RGD PMID:19748503 RGD:2316076 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:19748503 RGD:2316076 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like ISS MouseDO NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 ISO associated with Obesity, Morbid;mRNA:decreased expression:omentum, adipose tissue (human) RGD PMID:26504501 RGD:11049459 NCBI chr12:39,653,951...39,667,817
Ensembl chr12:39,653,953...39,667,849
JBrowse link
G Asip agouti signaling protein ISO associated with Obesity;DNA:mutation (mouse)
CTD Direct Evidence: marker/mechanism
CTD PMID:1473152, PMID:10426381 RGD:2314006 NCBI chr 3:150,492,010...150,579,870
Ensembl chr 3:150,574,473...150,579,870
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:19667185 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:23430896 PMID:23963299 PMID:25588603 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Casp3 caspase 3 IEP protein:increased expression:ovary RGD PMID:28412870 RGD:40400904 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11117918 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cavin1 caveolae associated protein 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr10:88,862,513...88,874,495
Ensembl chr10:88,860,733...88,874,528
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased expression:serum RGD PMID:18385799 RGD:2307062 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd36 CD36 molecule ISO protein:increased expression:macrophage RGD PMID:17551591 RGD:2307209 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40lg CD40 ligand ISO associated with Coronary Arteriosclerosis, Myocardial Infarction; protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdh23 cadherin-related 23 ISO ClinVar Annotator: match by term: Diabetes mellitus ClinVar PMID:30311386 NCBI chr20:29,857,018...30,263,758
Ensembl chr20:29,857,637...29,990,111
JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 ISO DNA:snp: :rs10946398(human) RGD PMID:19741467 RGD:2313940 NCBI chr17:36,451,031...37,157,882
Ensembl chr17:36,451,058...37,295,069
JBrowse link
G Cel carboxyl ester lipase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Clock clock circadian regulator ISS MouseDO NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:30311386 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12572680 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpb2 carboxypeptidase B2 ISO protein:increased expression, increased activity:plasma RGD PMID:14983223 RGD:2313643 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19233164 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Ctsb cathepsin B onset ISO DNA:transversion:cds:p.L26V (human) RGD PMID:18706099 RGD:2315528 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23307960 RGD:9491759 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cyb5r4 cytochrome b5 reductase 4 ISO RGD PMID:15247412 RGD:2315644 NCBI chr 8:94,693,273...94,757,989
Ensembl chr 8:94,693,290...94,757,988
JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 ISO DNA:polymorphisms:5' utr, cds:-344C>T, p.K173R (human) RGD PMID:11687612 RGD:2307297 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO associated with Smoking Inhalation Injury; DNA:polymorphism:3' UTR:5639T>C (human) RGD PMID:11996959 RGD:2307073 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 ISO DNA:polymorphism:multiple (human) RGD PMID:16788382 RGD:2307151 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) ISO ClinVar Annotator: match by term: Diabetes mellitus ClinVar PMID:17384640 PMID:19592391 PMID:22843165 PMID:23065766 PMID:23652419 PMID:24005482 PMID:24407472 PMID:25741868 PMID:30311386 NCBI chr13:78,857,638...78,885,464
Ensembl chr13:78,857,638...78,885,464
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:decreased expression:urine
protein:increased expression:plasma
RGD PMID:9212353, PMID:8914465 RGD:2313869, RGD:11060253 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F7 coagulation factor VII no_association IDA
ISO
IEP
protein:increased activity:plasma (rat) RGD PMID:10910004, PMID:15258325, PMID:10899350 RGD:2312393, RGD:2312391, RGD:1598920 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD PMID:20551625, PMID:11213886 RGD:7206845 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Foxp3 forkhead box P3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fuca1 alpha-L-fucosidase 1 ISO protein:decreased activity:blood platelets RGD PMID:3609421 RGD:2315945 NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
JBrowse link
G Fxn frataxin ISO DNA:deletion:exon (mouse)
associated with Friedrich Ataxia; DNA:repeats:intron:GAA (human)
RGD PMID:12925693, PMID:8815938 RGD:2307048, RGD:2307047 NCBI chr 1:242,123,975...242,152,834
Ensembl chr 1:242,123,975...242,152,834
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO protein:decreased activity:blood RGD PMID:24865682 RGD:10449112 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gad1 glutamate decarboxylase 1 IDA RGD PMID:1924335 RGD:728511 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gata6 GATA binding protein 6 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:20581743 PMID:22158542 PMID:23223019 PMID:24310933 PMID:25741868 PMID:28492532 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gc GC, vitamin D binding protein ISO protein:increased expression:ascitic fluid RGD PMID:20054029 RGD:5509921 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gck glucokinase ISO neonatal-onset diabetes mellitus,OMIM:606176;DNA:point mutation:exon:T228M
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:7542040 PMID:8325892 PMID:8433729 PMID:8446612 PMID:8454109 PMID:8897004 PMID:10447526 PMID:10525657 PMID:11942313 PMID:12442280 PMID:12955723 PMID:14517946 PMID:14517956 PMID:15102714 PMID:15305805 PMID:15448103 PMID:15667334 PMID:15752705 PMID:16602010 PMID:16731834 PMID:16965331 PMID:17204055 PMID:17353190 PMID:17389332 PMID:17573900 PMID:18056790 PMID:18399931 PMID:18407139 PMID:18414213 PMID:18481947 PMID:19069349 PMID:19150152 PMID:19187021 PMID:19228875 PMID:19339519 PMID:19358091 PMID:19551638 PMID:19564454 PMID:19790256 PMID:20337973 PMID:20458967 PMID:21104275 PMID:21831042 PMID:22028181 PMID:22035297 PMID:22389783 PMID:22493702 PMID:22611063 PMID:22773699 PMID:23506826 PMID:24430320 PMID:24918535 PMID:25015100 PMID:25741868 PMID:26467025 PMID:27059371 PMID:27080136 PMID:27106716 PMID:28492532 PMID:29510678, PMID:11372010 RGD:1601295 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Cystic Fibrosis; protein:increased activity:plasma RGD PMID:17888134 RGD:2315601 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gh1 growth hormone 1 ISO protein:increased expression:vitreous body
protein:increased secretion:plasma
RGD PMID:19463895, PMID:1132599 RGD:2315653, RGD:2315658 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gipr gastric inhibitory polypeptide receptor ISO human gene, mouse model RGD PMID:15582721 RGD:2312617 NCBI chr 1:80,063,047...80,073,223
Ensembl chr 1:80,063,049...80,073,223
JBrowse link
G Glis3 GLIS family zinc finger 3 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 1:246,380,816...246,564,385
Ensembl chr 1:246,380,889...246,785,360
JBrowse link
G Glp1r glucagon-like peptide 1 receptor TAS RGD PMID:12093887 RGD:625448 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gnb3 G protein subunit beta 3 no_association ISO DNA:polymorphism: :multiple (human) RGD PMID:16908025 RGD:2313206 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:decreased expression:skeletal muscle (mouse) RGD PMID:18936159, PMID:18562625 RGD:2312632, RGD:2312633 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gsr glutathione-disulfide reductase ISO protein:decreased activity:blood: RGD PMID:22540111 RGD:7257584 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO RGD PMID:16927413 RGD:2306632 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:16002077 RGD:5490997 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:22662265 PMID:25741868 PMID:27104957 PMID:28492532 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hgf hepatocyte growth factor ISO mRNA, protein:increased expression:cornea RGD PMID:16186340 RGD:2313569 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:15476492 RGD:2313755 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hnf1a HNF1 homeobox A ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:8945470 PMID:9032114 PMID:9112026 PMID:9133564 PMID:9166684 PMID:9287053 PMID:9313763 PMID:9867222 PMID:10333057 PMID:10585442 PMID:10634407 PMID:11058894 PMID:11289470 PMID:11463573 PMID:12359128 PMID:12453420 PMID:12453976 PMID:12488961 PMID:12574234 PMID:12618559 PMID:12627330 PMID:12675668 PMID:15114102 PMID:15277395 PMID:15522234 PMID:15726414 PMID:15761192 PMID:15841481 PMID:15928245 PMID:16046319 PMID:16186275 PMID:16274290 PMID:16917892 PMID:16963153 PMID:17033837 PMID:17116178 PMID:17192490 PMID:17425917 PMID:17440016 PMID:17496355 PMID:17573900 PMID:17601994 PMID:17700391 PMID:17924661 PMID:17937063 PMID:18003757 PMID:18332101 PMID:18414213 PMID:18513305 PMID:18811724 PMID:19150152 PMID:21224407 PMID:21395678 PMID:21648289 PMID:22432796 PMID:23348805 PMID:23610083 PMID:23624530 PMID:24097065 PMID:24728327 PMID:25555642 PMID:25741868 PMID:25935773 PMID:26110317 PMID:26431509 PMID:26467025 PMID:27083284 PMID:27899486 PMID:27913849 PMID:28938416 PMID:29207974 PMID:30155490 PMID:30663027 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hnf1b HNF1 homeobox B ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15930087 PMID:16249435 PMID:18065799 PMID:19639018 PMID:20633866 PMID:21775974 PMID:22114815 PMID:24033266 PMID:24041679 PMID:24097065 PMID:24429398 PMID:24897035 PMID:25536396 PMID:25700310 PMID:25741868 PMID:26899772 PMID:30259503 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:10983627 PMID:16946562 PMID:18414213 PMID:24033266 PMID:25741868 PMID:26467025 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hp haptoglobin ISO RGD PMID:12540619 RGD:1626347 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Ica1 islet cell autoantigen 1 IDA RGD PMID:7918678 RGD:633043 NCBI chr 4:34,635,509...34,780,187
Ensembl chr 4:34,635,506...34,780,193
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:19394054 RGD:2313467 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf1 insulin-like growth factor 1 ISO mRNA,protein:decreased expression:corpus cavernosum: RGD PMID:22133301 RGD:10046054 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO RGD PMID:16642022 RGD:2311506 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il10 interleukin 10 ISO RGD PMID:22802947 RGD:7364853 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha IMP RGD PMID:18503494 RGD:2311530 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il33 interleukin 33 IEP protein:increased expression:serum,ovary RGD PMID:28412870 RGD:40400904 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il6 interleukin 6 susceptibility ISO protein:increased expression:extracellular space (human)
mRNA:decreased expression:dendritic cell (mouse)
associated with Dementia; protein:increased expression:brain (human)
DNA:polymorphism:promoter:-174G>C (human)
RGD PMID:19442860, PMID:19120268, PMID:19139294, PMID:18689695 RGD:2307180, RGD:2307278, RGD:2307273, RGD:2307293 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins1 insulin 1 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:17855560 PMID:18162506 PMID:18192540 PMID:20226046 PMID:25542748 PMID:25741868 PMID:30311386 NCBI chr 1:272,799,784...272,800,351
Ensembl chr 1:272,799,784...272,800,347
JBrowse link
G Ins2 insulin 2 ISO DNA, protein:missense mutations, altered processing:exons, endoplasmic reticulum:multiple
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
CTD Direct Evidence: marker/mechanism
CTD Direct Evidence: marker/mechanism|therapeutic
DNA, protein:missense mutations:exons:multiple
protein:altered localization :endoplasmic reticulum
DNA:point mutation (mouse)
ClinVar
CTD
PMID:2055425 PMID:7294224 PMID:7624867 PMID:8400068 PMID:11446671 PMID:15628829 PMID:17855560 PMID:18162506 PMID:18192540 PMID:19775285 PMID:20226046 PMID:25542748 PMID:25741868 PMID:30311386, PMID:18451997, PMID:17855560, PMID:20034470, PMID:16799061, PMID:19537357 RGD:2317262, RGD:2317259, RGD:2317260, RGD:2311115, RGD:2311109 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insr insulin receptor ISO DNA:deletions, missense mutation:multiple (human)
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar PMID:2040394 PMID:2211730 PMID:2983222 PMID:8257688 PMID:8432414 PMID:8900242 PMID:10084586 PMID:11463381 PMID:25741868 PMID:27896077 PMID:28492532, PMID:18925540 RGD:2307343 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irs1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10591678 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga2 integrin subunit alpha 2 ISO protein:increased expression:monocyte (human) RGD PMID:17466965 RGD:2307424 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 susceptibility ISO DNA:deletion:exon:p.Q1715_R1731del (mouse) RGD PMID:21565852 RGD:6480678 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO DNA:mutation: :p.V59M (mouse)
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar Annotator: match by term: Monogenic diabetes
Diabetes Mellitus, permanent neonatal, OMIM:606176
ClinVar PMID:8897013 PMID:10338089 PMID:12524280 PMID:14715863 PMID:15115830 PMID:15292329 PMID:15504982 PMID:15562009 PMID:15580558 PMID:15583126 PMID:16357843 PMID:18250167 PMID:18414213 PMID:20685672 PMID:21115269 PMID:21119644 PMID:22701567 PMID:23275527 PMID:23345197 PMID:25741868 PMID:26467025 PMID:28492532 PMID:28787272, PMID:19065048, PMID:15292329, PMID:16416420 RGD:2311536, RGD:1625256, RGD:1625279 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kif1a kinesin family member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chr 9:100,171,851...100,253,626
Ensembl chr 9:100,171,772...100,253,609
JBrowse link
G Kif5b kinesin family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23776493 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
JBrowse link
G Klf11 Kruppel-like factor 11 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15774581 PMID:17130512 PMID:18414213 PMID:18593768 PMID:19122346 PMID:19843526 PMID:25741868 PMID:28492532 NCBI chr 6:43,829,812...43,841,649
Ensembl chr 6:43,829,945...43,841,651
JBrowse link
G Lep leptin ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:15028607 PMID:25741868 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lmna lamin A/C ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2007407 PMID:2270059 PMID:2526018 PMID:10587585 PMID:10655060 PMID:10739751 PMID:10810087 PMID:10868844 PMID:10999791 PMID:10999845 PMID:11078466 PMID:11102973 PMID:11136544 PMID:11180602 PMID:11792809 PMID:12057196 PMID:12927424 PMID:15060110 PMID:15219508 PMID:15770669 PMID:16181372 PMID:16364671 PMID:16415042 PMID:16585054 PMID:18035086 PMID:18414213 PMID:18478590 PMID:18728124 PMID:18795223 PMID:18926329 PMID:19011997 PMID:19201734 PMID:19418082 PMID:19589617 PMID:19859838 PMID:19875404 PMID:20074070 PMID:20130076 PMID:20497714 PMID:20625965 PMID:20848652 PMID:21535365 PMID:21831885 PMID:21980471 PMID:22177269 PMID:22199124 PMID:22276265 PMID:22355414 PMID:22526018 PMID:22570643 PMID:22700598 PMID:23313286 PMID:23349452 PMID:23427149 PMID:23853504 PMID:23861362 PMID:24033266 PMID:24080738 PMID:24375749 PMID:24503780 PMID:24623722 PMID:25025039 PMID:25163546 PMID:25448463 PMID:25637381 PMID:25741868 PMID:25873806 PMID:26467025 PMID:26498160 PMID:26662654 PMID:27000522 PMID:27153395 PMID:27447704 PMID:27532257 PMID:27896284 PMID:28087566 PMID:28492532 PMID:28620495 PMID:28641778 PMID:28663758 PMID:28701371 PMID:28807990 PMID:30311386 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lrp1 LDL receptor related protein 1 treatment IDA RGD PMID:22889684 RGD:13800521 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Mafa MAF bZIP transcription factor A treatment IEP RGD PMID:23801580 RGD:13506744 NCBI chr 7:116,779,368...116,781,815
Ensembl chr 7:116,780,681...116,781,766
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16731828 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mc4r melanocortin 4 receptor ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:9267995 PMID:10078568 PMID:10199800 PMID:10592235 PMID:10903341 PMID:12364414 PMID:12364415 PMID:12499395 PMID:12629567 PMID:12646665 PMID:12646666 PMID:12690102 PMID:12970296 PMID:14764812 PMID:14973783 PMID:15037865 PMID:15585384 PMID:15805150 PMID:15975705 PMID:16030156 PMID:16032553 PMID:16094248 PMID:16274851 PMID:16469222 PMID:16492696 PMID:16507637 PMID:16611215 PMID:16614075 PMID:17286227 PMID:17306938 PMID:17517246 PMID:17519222 PMID:17579204 PMID:17628007 PMID:17986382 PMID:18559663 PMID:19091795 PMID:19179454 PMID:20462274 PMID:22106157 PMID:22492873 PMID:23146882 PMID:23251400 PMID:23505181 PMID:23791567 PMID:24611737 PMID:24890885 PMID:25332687 PMID:25741868 PMID:26467025 PMID:27654141 PMID:28492532 PMID:30004997 PMID:31002796 PMID:154889963 NCBI chr18:62,612,838...62,614,725
Ensembl chr18:62,612,838...62,614,725
JBrowse link
G Mir223 microRNA 223 ISO RNA:decreased expression:blood mononuclear cell RGD PMID:26717922 RGD:14398486 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO RGD PMID:11159210 RGD:8693313 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO mRNA:increased expression:retina RGD PMID:11159210 RGD:8693313 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18273840 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L ISO DNA:deletion: :m.8213_13992 (human) RGD PMID:7603516 RGD:5686343 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27122239 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association ISO DNA:transition:cds:g.677C>T (human) RGD PMID:9607212 RGD:38501049 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nat2 N-acetyltransferase 2 ISO DNA:polymorphism RGD PMID:16397907 RGD:2311597 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Neurod1 neuronal differentiation 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Nppb natriuretic peptide B onset ISO RGD PMID:23733199 RGD:7246907 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 IEP mRNA:increased expression:pancreatic islet RGD PMID:17259388 RGD:2311606 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Pax4 paired box 4 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:15509590 PMID:18414213 PMID:25741868 NCBI chr 4:55,735,640...55,753,461
Ensembl chr 4:55,735,682...55,740,627
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO mRNA, decreased expression:pancreatic islet (mouse)
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar PMID:10545530 PMID:10545531 PMID:10720084 PMID:11022198 PMID:11270685 PMID:11315851 PMID:11914043 PMID:12618559 PMID:14764823 PMID:15001545 PMID:15170499 PMID:15277425 PMID:15754742 PMID:16092045 PMID:16741735 PMID:17126328 PMID:17592437 PMID:19228875 PMID:19515026 PMID:21569088 PMID:24097065 PMID:25741868 PMID:26058934 PMID:26467025 PMID:27535533 PMID:27879211 PMID:28492532 PMID:29439679 PMID:30930126, PMID:18682608 RGD:2308812 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Plin1 perilipin 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:18414213 PMID:25741868 PMID:28492532 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19153526 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16229851 PMID:19022366 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISS MouseDO NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO CTD Direct Evidence: therapeutic
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:16168052 PMID:19748282 PMID:25741868 PMID:27749844 PMID:28492532 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:12118251 PMID:25741868 PMID:28492532 NCBI chr 4:41,171,486...41,212,116
Ensembl chr 4:41,171,486...41,212,072
JBrowse link
G Prom1 prominin 1 IDA RGD PMID:11237753 RGD:68837 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G Pten phosphatase and tensin homolog IEP protein:increased expression, increased phosphorylation:inferior vena cava RGD PMID:16961925 RGD:2292543 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:25775927 PMID:28492532 NCBI chr17:86,199,623...86,201,477
Ensembl chr17:86,199,623...86,201,477
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15885672, PMID:15885672 RGD:5143927 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO DNA: snp: cds: C1858T RGD PMID:18764813 RGD:6484729 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rfx6 regulatory factor X, 6 ISO ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:15592663 PMID:18414213 PMID:20148032 PMID:25741868 PMID:28492532 PMID:29026101 NCBI chr20:32,709,282...32,764,040
Ensembl chr20:32,717,564...32,764,035
JBrowse link
G Serpina7 serpin family A member 7 ISO RGD PMID:8742570 RGD:2312329 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:10910004 RGD:2312393 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Shbg sex hormone binding globulin ISO protein:increased expression:plasma RGD PMID:18346991 RGD:2313784 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Shld2 shieldin complex subunit 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532 NCBI chr16:10,570,307...10,661,528
Ensembl chr16:10,570,314...10,661,528
JBrowse link
G Sim1 SIM bHLH transcription factor 1 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:2152513 PMID:16924270 PMID:21512513 PMID:23778136 PMID:23778139 PMID:25234154 PMID:25741868 PMID:28492532 NCBI chr20:55,590,810...55,674,002
Ensembl chr20:55,594,676...55,673,995
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894401 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc19a2 solute carrier family 19 member 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:25741868 PMID:28492532, PMID:10391221 RGD:1599325 NCBI chr13:82,552,586...82,566,586
Ensembl chr13:82,552,550...82,566,586
JBrowse link
G Slc22a12 solute carrier family 22 member 12 IEP protein:decreased expression:kidney RGD PMID:28679589 RGD:13439745 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO RGD PMID:10022440 RGD:12879500 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO ClinVar Annotator: match by term: Monogenic diabetes ClinVar PMID:8027028 PMID:8063045 PMID:11810292 PMID:23986439 PMID:25741868 PMID:28492532 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a3 solute carrier family 2 member 3 ISO RGD PMID:10086067 RGD:2313619 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23786522 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:12830380 RGD:1581299 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO ClinVar Annotator: match by term: Diabetes mellitus ClinVar PMID:10835640 PMID:15980664 PMID:16849362 PMID:18978175 PMID:23017645 PMID:23741238 PMID:25741868 PMID:26632706 PMID:28492532 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:12749121 RGD:1600067 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO associated with Cystic Fibrosis;DNA:SNP (human) RGD PMID:19585101 RGD:2312417 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tfpi tissue factor pathway inhibitor ISO protein:increased expression:plasma: RGD PMID:8914465 RGD:11060253 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tgm6 transglutaminase 6 ISO ClinVar Annotator: match by term: Diabetes mellitus ClinVar PMID:25741868 PMID:30311386 NCBI chr 3:122,644,183...122,680,054
Ensembl chr 3:122,662,086...122,679,128
JBrowse link
G Thbs2 thrombospondin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23723366 NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO protein:decreased expression:glomerulus RGD PMID:19506087 RGD:2312464 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tlr4 toll-like receptor 4 ISO protein:increased expression:monocyte RGD PMID:19210958, PMID:15632890 RGD:2312485, RGD:1580736 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 ISO RGD PMID:10192335 RGD:2312735 NCBI chr 5:163,186,349...163,231,578
Ensembl chr 5:163,186,349...163,231,578
JBrowse link
G Ucp3 uncoupling protein 3 ISO RGD PMID:17587402 RGD:2313514 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Vdr vitamin D receptor no_association ISO DNA:SNPs: :rs731236, rs1544410, rs7975232 (human) RGD PMID:22856230 RGD:8158070 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vwf von Willebrand factor treatment ISO RGD PMID:19722571 RGD:7207029 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein ISO DNA:missense mutations:cds:p.R456H, p.R611H (rs1801206, rs1801214) (human)
ClinVar Annotator: match by term: Monogenic diabetes
ClinVar Annotator: match by term: Diabetes mellitus
ClinVar PMID:10521293 PMID:10624825 PMID:10679252 PMID:11161832 PMID:11244483 PMID:11317350 PMID:11694551 PMID:11709537 PMID:11709538 PMID:11811080 PMID:11916957 PMID:11920861 PMID:12073007 PMID:12107816 PMID:12565131 PMID:12754709 PMID:12782971 PMID:12913071 PMID:12955714 PMID:15008830 PMID:15234338 PMID:15277431 PMID:15473915 PMID:15605410 PMID:15852062 PMID:17492394 PMID:17568405 PMID:18414213 PMID:18544103 PMID:19042979 PMID:19292454 PMID:19344068 PMID:20738327 PMID:20875904 PMID:21446023 PMID:21602428 PMID:22226368 PMID:22238590 PMID:22797899 PMID:23429432 PMID:23595122 PMID:23981289 PMID:24033266 PMID:24875298 PMID:24890733 PMID:24909696 PMID:25133958 PMID:25173644 PMID:25262649 PMID:25497598 PMID:25741868 PMID:25895475 PMID:26025012 PMID:26435059 PMID:26467025 PMID:26969326 PMID:27068579 PMID:27395765 PMID:27468121 PMID:27617222 PMID:28432734 PMID:28492532 PMID:29529044 PMID:30014265, PMID:23595122 RGD:8694404 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
G Zfp57 zinc finger protein 57 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Monogenic diabetes
CTD
ClinVar
PMID:18414213 PMID:18622393 PMID:23748067 PMID:25741868 NCBI chr20:2,014,177...2,020,488
Ensembl chr20:2,014,170...2,020,537
JBrowse link
autosomal dominant Wolfram syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wfs1 wolframin ER transmembrane glycoprotein ISO ClinVar Annotator: match by term: HEARING LOSS, PROGRESSIVE, WITH OPTIC ATROPHY AND/OR IMPAIRED GLUCOSE REGULATION
ClinVar Annotator: match by term: Wolfram-like syndrome, autosomal dominant
ClinVar Annotator: match by OMIM:614296
OMIM
ClinVar
PMID:10679252 PMID:11295831 PMID:12022290 PMID:15605410 PMID:16648378 PMID:17492394 PMID:18544103 PMID:19877185 PMID:20069065 PMID:20875904 PMID:21067485 PMID:21143470 PMID:21538838 PMID:21917145 PMID:22238590 PMID:24033266 PMID:24890733 PMID:25133958 PMID:25388789 PMID:25741868 PMID:26435059 PMID:26467025 PMID:26875006 PMID:27395765 PMID:28432734 PMID:28468959 PMID:28492532 PMID:29529044 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
background diabetic retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin treatment ISO RGD PMID:10848441 RGD:10046010 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Cat catalase ISO associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum: RGD PMID:24092995 RGD:9068931 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO protein:decreased expression:aqueous humor: RGD PMID:23853629 RGD:10402120 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO protein:decreased expression:vitreous: RGD PMID:19799585 RGD:10449447 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
chromosome 17q11.2 deletion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf135 ring finger protein 135 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Macrocephaly, macrosomia, facial dysmorphism syndrome
CTD
ClinVar
PMID:17632510 PMID:21681106 PMID:27535533 PMID:28135719 PMID:30665703 PMID:30763456 NCBI chr10:67,531,989...67,551,237 JBrowse link
Cleft Palate, Proliferative Retinopathy, and Developmental Delay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrc32 leucine rich repeat containing 32 ISO ClinVar Annotator: match by term: CLEFT PALATE, PROLIFERATIVE RETINOPATHY, AND DEVELOPMENTAL DELAY ClinVar
OMIM
PMID:30976112 NCBI chr 1:163,443,972...163,457,426
Ensembl chr 1:163,445,527...163,457,424
JBrowse link
Combined Cerebellar and Peripheral Ataxia with Hearing Loss and Diabetes Mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 ISO ClinVar Annotator: match by term: Ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus OMIM
ClinVar
PMID:25466870 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 ISO ClinVar Annotator: match by term: Ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus ClinVar PMID:2256350 PMID:22563501 PMID:24220513 PMID:32214227 NCBI chr 5:120,330,372...120,492,515
Ensembl chr 5:120,340,646...120,492,487
JBrowse link
Developmental Delay, Epilepsy, and Neonatal Diabetes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO ClinVar Annotator: match by term: DEND syndrome ClinVar PMID:25741868 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
Diabetes Complications term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25304492 PMID:25541468 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: therapeutic CTD PMID:23500772 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:20479236 RGD:7241550 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO RGD PMID:20479236 RGD:7241550 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Casp9 caspase 9 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:24252320 RGD:13782355 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 ISO RGD PMID:15963101 RGD:2307154 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO Associated with obesity RGD PMID:21282363 RGD:6906933 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO protein: decreased expression: serum RGD PMID:18025762 RGD:7242563 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Glo1 glyoxalase 1 no_association ISO DNA:SNP: :419C>A (human) RGD PMID:21738003 RGD:7242569 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19769483 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Muc1 mucin 1, cell surface associated IEP associated with Diabetes Mellitus, Experimental RGD PMID:23977093 RGD:7349380 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Pln phospholamban IEP associated with Diabetes Mellitus, Experimental;mRNA:increased expression:diaphragm RGD PMID:23443767 RGD:7327179 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19003935 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 IDA associated with Diabetes Mellitus, Experimental RGD PMID:21548839 RGD:6484542 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Slc10a2 solute carrier family 10 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr16:90,324,420...90,350,254
Ensembl chr16:90,324,361...90,345,865
JBrowse link
G Slc51a solute carrier family 51 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr11:71,533,078...71,547,476
Ensembl chr11:71,533,078...71,547,476
JBrowse link
G Slc51b solute carrier family 51 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29382564 NCBI chr 8:70,930,196...70,938,559
Ensembl chr 8:70,930,347...70,932,986
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP associated with Diabetes Mellitus, Experimental RGD PMID:18057998 RGD:6771339 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26073000 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
Diabetes Mellitus, Congenital Autoimmune term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12930356 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258
JBrowse link
Diabetes Mellitus, New-Onset after Transplantation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:22645144 RGD:10040997 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
diabetic angiopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO ClinVar Annotator: match by term: END-STAGE RENAL DISEASE, DIABETIC, SUSCEPTIBILITY TO ClinVar
OMIM
PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 PMID:2847529 PMID:2849100 PMID:7593601 PMID:7729604 PMID:7854377 PMID:7909524 PMID:8131299 PMID:8131300 PMID:8136829 PMID:8170965 PMID:8208911 PMID:8298638 PMID:8314010 PMID:8541160 PMID:8644984 PMID:8675669 PMID:9120002 PMID:9236417 PMID:9259580 PMID:9699903 PMID:9737775 PMID:9916793 PMID:10099885 PMID:10636736 PMID:10643899 PMID:10841123 PMID:11687636 PMID:11956052 PMID:12220450 PMID:12666117 PMID:14657821 PMID:14872014 PMID:15110771 PMID:15277638 PMID:15381116 PMID:15531537 PMID:15534175 PMID:15635071 PMID:19221299 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adcy3 adenylate cyclase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 6:28,570,941...28,648,848
Ensembl chr 6:28,571,351...28,650,148
JBrowse link
G Adcy8 adenylate cyclase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20372816 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19733855 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ass1 argininosuccinate synthase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25033204 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Bdkrb1 bradykinin receptor B1 IMP RGD PMID:15878326 RGD:7241570 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:23154660 RGD:11526153 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cd28 Cd28 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased expression:T cell RGD PMID:15504310 RGD:2307197 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:14963650 RGD:2314223 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 susceptibility ISO associated with Diabetic Foot;DNA:polymorphism:3' utr (human) RGD PMID:16723689 RGD:2306558 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Epo erythropoietin ISO ClinVar Annotator: match by OMIM:612623 OMIM
ClinVar
PMID:18458324 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
protein:increased expression:plasma
RGD PMID:16371118, PMID:9285207 RGD:2313861, RGD:2313868 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fas Fas cell surface death receptor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15803113 RGD:2315753 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism
CTD PMID:25381014, PMID:15803113 RGD:2315753 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fn1 fibronectin 1 IDA RGD PMID:12716757 RGD:1601179 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:21411989 RGD:7242686 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics RGD PMID:16338763 RGD:1600708 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics RGD PMID:16338763 RGD:1600708 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hfe homeostatic iron regulator ISO ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO OMIM
ClinVar
PMID:678784 PMID:8696333 PMID:8896549 PMID:8896550 PMID:8931958 PMID:8943161 PMID:9024376 PMID:9106528 PMID:9138148 PMID:9162021 PMID:9211748 PMID:9321765 PMID:9326341 PMID:9341868 PMID:9356458 PMID:9439654 PMID:9462220 PMID:9482831 PMID:9585606 PMID:9851896 PMID:9851897 PMID:10381492 PMID:10401000 PMID:10431233 PMID:11358905 PMID:11399207 PMID:11423500 PMID:11479183 PMID:11532995 PMID:11812557 PMID:11874997 PMID:11904676 PMID:12241803 PMID:12429850 PMID:12436244 PMID:12885340 PMID:12915468 PMID:14618419 PMID:14673107 PMID:14729817 PMID:15060098 PMID:15070663 PMID:15280838 PMID:15347835 PMID:15858186 PMID:16132052 PMID:16879202 PMID:17600748 PMID:17828789 PMID:18199861 PMID:18499578 PMID:18504828 PMID:18566337 PMID:19084217 PMID:19159930 PMID:19444013 PMID:19554541 PMID:20301613 PMID:21243428 PMID:21452290 PMID:22531912 PMID:24033266 PMID:24729993 PMID:25741868 PMID:25741869 PMID:26153218 PMID:26365338 PMID:27124787 PMID:28443246 PMID:28492532 PMID:28617828 PMID:30291871 PMID:30311386 PMID:31220083 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16959961 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Icam1 intercellular adhesion molecule 1 IDA
ISO
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:aorta
RGD PMID:18796303, PMID:18093596 RGD:2313473, RGD:2306988 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO ClinVar Annotator: match by OMIM:612628 OMIM
ClinVar
PMID:8500797 PMID:8786086 PMID:10025794 PMID:10746728 PMID:10750554 PMID:15286433 PMID:16636119 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO RGD PMID:12477149 RGD:1582581 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16681562 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nos2 nitric oxide synthase 2 IEP
IMP
associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea RGD PMID:19241604, PMID:19587355 RGD:4891384, RGD:2313210 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP
ISO
associated with Diabetes Mellitus, Experimental; protein:increased expression:cochlea
CTD Direct Evidence: marker/mechanism
CTD PMID:12124201, PMID:19241604, PMID:29329611 RGD:4891384, RGD:13504708 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased tyrosine phosphorylation:conceptus RGD PMID:10329590 RGD:2311657 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Plat plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:18945481 RGD:2311663 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pon1 paraoxonase 1 ISO associated with Diabetes Mellitus;DNA:polymorphisms: p.L55M, p.Q192R (human)
ClinVar Annotator: match by OMIM:612633
ClinVar
OMIM
PMID:9011577 PMID:9661650 PMID:11335891 PMID:11788650 PMID:11889198 PMID:11918623, PMID:17949258 RGD:2313270 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta treatment IDA associated with Diabetes Mellitus, Type 2 RGD PMID:21926342 RGD:10041069 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO associated with Diabetes Mellitus Type 1;DNA:polymorphism: :HLA-DRB1*03:01(human) RGD PMID:23376458 RGD:7365114 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:deletion, haplotype:promoter:g.-676_-674delG (human) RGD PMID:9844142 RGD:8547700 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf1 serpin family F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO ClinVar Annotator: match by term: NEPHROPATHY, DIABETIC, SUSCEPTIBILITY TO OMIM
ClinVar
PMID:8633092 PMID:10425186 PMID:12624725 PMID:15591282 PMID:16538174 PMID:17192491 PMID:19509150 PMID:22992668 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:mesentery, blood vessel RGD PMID:10625572 RGD:2300063 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thbs2 thrombospondin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25381014 NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:c.-308G>A (human) RGD PMID:18575614 RGD:2313255 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vegfa vascular endothelial growth factor A IEP
ISO
protein:increased expression:cochlea:
ClinVar Annotator: match by term: PROLIFERATIVE RETINOPATHY, DIABETIC, SUSCEPTIBILITY TO
OMIM
ClinVar
PMID:11978667, PMID:19241604 RGD:4891384 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
Diabetic Cardiomyopathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:21742475 RGD:10046044 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Ace angiotensin I converting enzyme treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:22595130 RGD:9685456 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acot1 acyl-CoA thioesterase 1 ISO associated with type 2 diabetes mellitus RGD PMID:23226270 RGD:13831128 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEP associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor1 adiponectin receptor 1 IEP associated with Diabetes Mellitus, Type2;mRNA, protein:decreased expression:heart, serum RGD PMID:24669271 RGD:8695938 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IEP
IDA
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:heart (rat) RGD PMID:23251674, PMID:23251674 RGD:7244283, RGD:7244283 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29353218 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15587404 PMID:16025228 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: therapeutic CTD PMID:18332268 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 IEP
ISO
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD PMID:16685413, PMID:21441944 RGD:6771209 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp7a ATPase copper transporting alpha treatment IMP RGD PMID:24927960 RGD:11341676 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:21296063 RGD:10053697 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA
ISO
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:myocardium (mouse)
RGD PMID:21296063, PMID:21474815 RGD:10053697, RGD:11522727 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp12 caspase 12 treatment IEP associated with Experimental Diabetes Mellitus RGD PMID:26869403 RGD:13782171 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:28992627 RGD:13782299 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:28992627 RGD:13782299 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:28992627 RGD:13782299 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casq2 calsequestrin 2 IDA associated with Diabetes Mellitus, Experimental RGD PMID:21441944 RGD:6771209 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Casr calcium-sensing receptor IEP protein:decreased expression:myocardium (rat) RGD PMID:22137362 RGD:7205677 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cfl1 cofilin 1 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:27576917 RGD:11568692 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Ctnnb1 catenin beta 1 IEP mRNA,protein:increased expression:heart RGD PMID:25586361 RGD:13524855 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IEP associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IEP associated with Diabetes Mellitus, Experimental;mRNA:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23853776, PMID:23453443 RGD:9586347, RGD:10412713 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:11375343 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:23843977 RGD:7247697 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20828608 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16129698 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:25907942 RGD:13800893 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mylk2 myosin light chain kinase 2 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:9005973 RGD:1580244 NCBI chr 3:148,386,185...148,397,851
Ensembl chr 3:148,386,189...148,399,501
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment IEP
ISO
associated with Diabetes Mellitus, Experimental RGD PMID:23453443, PMID:23353773 RGD:10412713, RGD:10412721 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:29274332 RGD:13504685 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:23497378 RGD:7297056 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nrg1 neuregulin 1 IEP associated with Diabetes Mellitus, Experimental;protein:decreased expresssion:left ventricle myocardium RGD PMID:22285193 RGD:10449013 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Pln phospholamban IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:heart left ventricle RGD PMID:22185592 RGD:7327207 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IDA Strain: ZDF RGD PMID:19317897 RGD:5509944 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ryr2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16685413 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Slc25a4 solute carrier family 25 member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:18945756 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc8a1 solute carrier family 8 member A1 treatment IEP RGD PMID:27058979 RGD:13628396 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16980342 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tert telomerase reverse transcriptase treatment IEP associated with Diabetes Mellitus, Type 2 RGD PMID:21264070 RGD:11038677 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17909696 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Xdh xanthine dehydrogenase treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:23843977 RGD:7247697 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
diabetic cataract term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsr glutathione-disulfide reductase ISO RGD PMID:12518238 RGD:10401829 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
Diabetic Cystopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IDA protein:increased expression:nuclei: RGD PMID:20879002 RGD:10053565 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:23129268 RGD:10053664 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Casp12 caspase 12 IEP associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:urinary bladder detrusor smooth muscle RGD PMID:26370333 RGD:13782173 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
Diabetic Embryopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain ISO RGD PMID:26419589 RGD:13792560 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
diabetic encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23529380, PMID:24291733 RGD:7244255, RGD:8553040 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G App amyloid beta precursor protein treatment IEP associated with type 2 diabetes mellitus RGD PMID:28885995 RGD:13782056 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP associated with Diabetes Mellitus, Experimental RGD PMID:17601561 RGD:7771546 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:26970304 RGD:13792771 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Ide insulin degrading enzyme ISO associated with type 2 diabetes mellitus RGD PMID:27306699 RGD:13792796 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Ngf nerve growth factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:24291733 RGD:8553040 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
Diabetic Foot term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:plasma RGD PMID:20836881 RGD:5686889 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO associated with Diabetes Mellitus, Type 2;protein:decreased expression:blood RGD PMID:21941211 RGD:6767555 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Crp C-reactive protein disease_progression ISO protein:increased expression:blood: RGD PMID:22712631 RGD:6906887 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO protein:increased expression:dermis RGD PMID:22455314 RGD:7207269 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B severity ISO DNA:polymorphism: :1538G>A (human) RGD PMID:19731315 RGD:8662463 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Igf1 insulin-like growth factor 1 ISO protein:decreased expression:fibroblast of dermis,stratum basale of epidermis: RGD PMID:10727985 RGD:8549356 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il15 interleukin 15 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:dermis, endothelial cell RGD PMID:17014667 RGD:2313575 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Mbl2 mannose binding lectin 2 ISO protein:increased expression:serum: RGD PMID:19997692 RGD:8694068 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mmp9 matrix metallopeptidase 9 severity ISO RGD PMID:22688339 RGD:8547813 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Plat plasminogen activator, tissue type ISO RGD PMID:17275886 RGD:2311669 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Ptx3 pentraxin 3 ISO protein:decreased expression:plasma (human) RGD PMID:30767386 RGD:38501100 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:SNPs,haplotype: :rs4986790,rs4986791,rs10759931,rs1927911(human); RGD PMID:23936790 RGD:7777174 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
diabetic ketoacidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 ISO RGD PMID:12021537 RGD:2314345 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:11430560 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insr insulin receptor ISO RGD PMID:15254588 RGD:1302526 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Pax4 paired box 4 susceptibility ISO ClinVar Annotator: match by term: Diabetes mellitus, ketosis-prone, susceptibility to ClinVar
OMIM
PMID:15509590 PMID:18414213 PMID:25741868 NCBI chr 4:55,735,640...55,753,461
Ensembl chr 4:55,735,682...55,740,627
JBrowse link
G Serpina7 serpin family A member 7 ISO protein:decreased expression:serum RGD PMID:6768790 RGD:2312332 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
Diabetic Nephropathies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme treatment
no_association
susceptibility
IMP
ISO
IDA
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:insertion/deletion
associated with Diabetes Mellitus, Type 1;DNA:insertion/deletion
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
CTD PMID:7909524 PMID:10099885 PMID:10857950 PMID:23733546, PMID:19301230, PMID:23803175, PMID:11938025, PMID:10862638, PMID:7729604, PMID:8314010, PMID:15118671 RGD:2311449, RGD:11039044, RGD:8548885, RGD:8548872, RGD:7829780, RGD:7829777, RGD:1331525 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 no_association ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple (human)
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:decreased expression:kidney
mRNA, protein:altered expression:kidney
associated with Diabetes Mellitus, Experimental
CTD PMID:12623933 PMID:17600118 PMID:20844835, PMID:18235039, PMID:19034303, PMID:19077419, PMID:18235039 RGD:2313800, RGD:2313797, RGD:2313796, RGD:2313800 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acvr1 activin A receptor type 1 IEP associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:11675415 RGD:2313802 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression
no_association
ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs1501299 (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs2241766 (human)
CTD PMID:17942768, PMID:21945031, PMID:17970779, PMID:23260797, PMID:23260797 RGD:5686409, RGD:8694475, RGD:8694443, RGD:8694443 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adora1 adenosine A1 receptor IMP associated with Diabetes Mellitus, Experimental RGD PMID:19552053 RGD:2313803 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adra2b adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism (human) RGD PMID:15660746 RGD:2313545 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:9867224 RGD:5684403 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility
treatment
IEP
ISO
IDA
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney cortex, glomerulus
associated with Diabetes Mellitus, Type 2;protein:increased expression:renal cortex (mouse)
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1704G>T (human)
associated with Diabetes Mellitus;DNA:polymorphisms, haplotype:cds, intron:p.G82S, g.2184A>G (rs2070600, rs3134940) (human)
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
RGD PMID:19142024, PMID:12651605, PMID:14747204, PMID:21533139, PMID:23091285, PMID:21856399, PMID:12651605 RGD:2325651, RGD:7243248, RGD:8695982, RGD:7244187, RGD:7244174, RGD:7243852, RGD:7243248 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen disease_progression
no_association
ISO CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :p.M235T (human)
associated with Diabetes Mellitus, Type 1;DNA:polymorphism: :p.M235T (human)
CTD PMID:17890855 PMID:20383342, PMID:15118671, PMID:19014923, PMID:11938025, PMID:10862638, PMID:8772723 RGD:1331525, RGD:11039058, RGD:8548885, RGD:8548872, RGD:8548868 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP
ISO
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:polymorphism: :1166A>C (human)
RGD PMID:12172324, PMID:12476891 RGD:6903861, RGD:8548891 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IEP associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney RGD PMID:18565281 RGD:6903847 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Ahsg alpha-2-HS-glycoprotein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15698447 RGD:2313813 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B susceptibility ISO associated with Diabetes Mellitus, Type 1;DNA:promoter:repeat:g.?(AC)n (human) RGD PMID:9215310, PMID:9000706 RGD:734542, RGD:8548641 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Alb albumin IEP
ISO
associated with Metabolic Syndrome X;protein:increased expression:urine
CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Experimental;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
CTD PMID:16380483, PMID:19424163, PMID:21441310, PMID:19397971, PMID:19246226 RGD:2306882, RGD:5135032, RGD:2306885, RGD:2306886 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alpk1 alpha-kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 2:231,997,360...232,117,471
Ensembl chr 2:231,996,088...232,117,134
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14977883 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apoa1 apolipoprotein A1 ISO RGD PMID:9829487 RGD:2313960 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum RGD PMID:11126402, PMID:9829487 RGD:2313958, RGD:2313960 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apob apolipoprotein B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19324028 RGD:2313979 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc1 apolipoprotein C1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:very-low-density lipoprotein particle RGD PMID:12753304 RGD:2313950 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc3 apolipoprotein C3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-455T>C RGD PMID:16813599 RGD:2306755 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E susceptibility
no_association
ISO DNA:missense mutations, haplotype:cds:p.C112R, p.R158C (human)
associated with Diabetes Mellitus, type 1;
associated with Diabetes Mellitus, Experimental
RGD PMID:21127830, PMID:11495633, PMID:22859852 RGD:6903840, RGD:7771553, RGD:6902935 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apoh apolipoprotein H ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:11302005 RGD:2313989 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Aqp2 aquaporin 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased secretion:urine RGD PMID:12218327 RGD:2314343 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Arg2 arginase 2 ISO RGD PMID:21926276 RGD:6902923 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta treatment IDA mRNA:decreased expression:renal glomerulus (rat) RGD PMID:22591908 RGD:13792578 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Axl Axl receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472, PMID:15619028 RGD:1579938 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Azin1 antizyme inhibitor 1 treatment IEP RGD PMID:26751697 RGD:14700801 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Bdkrb2 bradykinin receptor B2 susceptibility ISO associated with Diabetes Mellitus, Experimental RGD PMID:17596525 RGD:2313335 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor IMP RGD PMID:20557422 RGD:4891134 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:kidney RGD PMID:21866636 RGD:6483069 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO associated with Diabetes Mellitus, Type2; protein:increased expression:serum: RGD PMID:9347246 RGD:7207424 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bmp7 bone morphogenetic protein 7 IEP RGD PMID:17437042 RGD:2289036 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G C3 complement C3 ISO
IEP
associated with Diabetes Mellitus, Type 1; protein:increased expression:kidney:
associated with Diabetes Mellitus, Type 2
RGD PMID:19200691, PMID:25662584 RGD:7183082, RGD:11040807 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 IEP associated with Diabetes Mellitus, Type 2 RGD PMID:25662584 RGD:11040807 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B treatment ISO RGD PMID:27273361 RGD:13506726 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Capn10 calpain 10 IEP associated with Diabetes Mellitus, Experimental RGD PMID:22012129 RGD:7247733 NCBI chr 9:100,104,000...100,112,833
Ensembl chr 9:100,104,000...100,112,832
JBrowse link
G Casp12 caspase 12 IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney RGD PMID:19301230 RGD:2311449 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IEP associated with Diabetes Mellitus, Experimental;protein:increased activity:kidney
associated with Diabetes Mellitus, Experimental
associated with type 2 diabetes mellitus
RGD PMID:19601660, PMID:29606028, PMID:28456626 RGD:2311440, RGD:13792586, RGD:13782304 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 treatment IEP associated with type 2 diabetes mellitus RGD PMID:28456626 RGD:13782304 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 treatment IEP associated with type 2 diabetes mellitus
associated with Diabetes Mellitus, Experimental
RGD PMID:28456626, PMID:29606028 RGD:13782304, RGD:13792586 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:30038056, PMID:29606028 RGD:13782342, RGD:13792586 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase ISO
IMP
IDA
IEP
rat gene in db/db mice
associated with experimentally induced diabetes
RGD PMID:22315314, PMID:20299359, PMID:21525431, PMID:21686137 RGD:7205651, RGD:7205676, RGD:7205665, RGD:7205662 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 ISO associated with Diabetes Mellitus, Type 2 RGD PMID:21113841 RGD:5683918 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 susceptibility
disease_progression
ISO
IEP
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
CTD PMID:16374426, PMID:17968528, PMID:19369290, PMID:19409809, PMID:19097668, PMID:18031723 RGD:2306991, RGD:2306980, RGD:2306979, RGD:2306982, RGD:2306989 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 IEP associated with Diabetes Mellitus, Experimental RGD PMID:17664181 RGD:7483629 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-28C>G
associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:urine
RGD PMID:12610055, PMID:18326229 RGD:2307107, RGD:2307063 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn2 cellular communication network factor 2 IEP associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney, glomerulus (rat)
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat)
RGD PMID:19895808, PMID:19065061 RGD:2314366, RGD:2314604 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccne1 cyclin E1 IEP protein:increased expression:kidney RGD PMID:17825795 RGD:2289273 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 no_association ISO associated with Diabetes Mellitus, Insulin-Dependent
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.V64I (human)
RGD PMID:17631861, PMID:11756347 RGD:2313558, RGD:2313563
G Ccr5 C-C motif chemokine receptor 5 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:59029G>A (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP: :59029G>A (human)
RGD PMID:12610055, PMID:17428349 RGD:2307107, RGD:8549756 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd36 CD36 molecule IEP protein:increased expression:renal proximal tubule, endothelial cell RGD PMID:15737001 RGD:2307215 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd38 CD38 molecule IMP
ISO
associated with Diabetes Mellitus, Experimental RGD PMID:19073639, PMID:19300526 RGD:2307227, RGD:2307228 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd40lg CD40 ligand ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:serum RGD PMID:18756582 RGD:2314208 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27652271 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP mRNA, protein:increased expression:kidney, glomerulus RGD PMID:15698433, PMID:16805985 RGD:2293628, RGD:2293619 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cfl1 cofilin 1 IEP associated with Diabetes Mellitus, Experimental;protein:increased phosphorylation:renal glomerulus (rat) RGD PMID:24726496 RGD:11570419 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Clu clusterin treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:18949565 RGD:9068414 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cndp1 carnosine dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17942768 PMID:21393041 PMID:21573905, PMID:21393041 RGD:7207213 NCBI chr18:81,466,717...81,512,841
Ensembl chr18:81,466,716...81,499,051
JBrowse link
G Cndp2 carnosine dipeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21573905 NCBI chr18:81,521,966...81,539,065
Ensembl chr18:81,521,968...81,539,065
JBrowse link
G Col1a1 collagen type I alpha 1 chain IEP associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus (rat) RGD PMID:22903132 RGD:8552684 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
CTD PMID:18682491 PMID:27997345, PMID:19466391, PMID:17582205 RGD:2311340, RGD:2311342 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Cpb2 carboxypeptidase B2 susceptibility ISO DNA:SNP:cds:1040C>T(human)
protein:increased expression:plasma
RGD PMID:22932273, PMID:12574207 RGD:7243116, RGD:7243123 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Creb1 cAMP responsive element binding protein 1 susceptibility IEP RGD PMID:15862029 RGD:10059365 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crp C-reactive protein disease_progression ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2;protein:increased expression:urine
RGD PMID:22885250, PMID:22590912 RGD:6906965, RGD:6906967 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf1r colony stimulating factor 1 receptor disease_progression ISO associated with Diabetes Mellitus, Type 2 RGD PMID:19466391 RGD:2311340 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cst3 cystatin C IEP
ISO
protein:increased expression:plasma (rat)
protein:increased expression:serum (human)
RGD PMID:18946178, PMID:19132849 RGD:2314297, RGD:2314328 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased expression:plasma: RGD PMID:18026823 RGD:2312302 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Cubn cubilin IEP RGD PMID:17037740 RGD:1599655 NCBI chr17:80,584,921...80,807,181
Ensembl chr17:80,584,878...80,807,243
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent
RGD PMID:17425653, PMID:19073786 RGD:2311359, RGD:2311357 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:22791342 RGD:7257674 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cyba cytochrome b-245 alpha chain ISO associated with Diabetes Mellitus, Type 2;DNA:SNP: :242C>T (human) RGD PMID:14747204 RGD:8695982 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-344C>T (human) RGD PMID:16672053 RGD:2307295 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:promoter:-344C>T (human) RGD PMID:16672053 RGD:2307295 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment IMP associated with Diabetes Mellitus, Experimental RGD PMID:22301628 RGD:7257708 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 ISO associated with Diabetes Mellitus, Experimental; RGD PMID:21742052 RGD:7243153 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Dcn decorin ISO associated with Diabetes Mellitus, Insulin-Dependent
protein:increased expression:plasma, urine
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Insulin-Dependent;mRNA, protein:decreased expression:kidney cortex, glomerulus
RGD PMID:12187087, PMID:11259366, PMID:17884968, PMID:16868749 RGD:2311415, RGD:2311416, RGD:2311411, RGD:2311412 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dgkh diacylglycerol kinase, eta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr15:60,791,574...60,967,236
Ensembl chr15:60,803,098...60,959,769
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 IMP associated with Diabetes Mellitus, Experimental RGD PMID:20019166 RGD:6907383 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Edn1 endothelin 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased secretion:plasma (human) RGD PMID:18346810 RGD:2313284 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A IMP associated with Diabetes Mellitus, Experimental RGD PMID:21191784 RGD:4892326 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Egf epidermal growth factor ISO RGD PMID:17475821 RGD:6906912 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Elmo1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17942768 NCBI chr17:46,352,102...46,888,788
Ensembl chr17:46,353,330...46,794,845
JBrowse link
G Eng endoglin ISO associated with Diabetes Mellitus, Insulin-Dependent; mRNA:increased expression:kidney RGD PMID:19395281 RGD:2313795 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:19506043 RGD:6906926 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Ep300 E1A binding protein p300 treatment IEP
IDA
associated with Diabetes Mellitus, Experimental; mRNA, protein:increased expression:kidney (rat) RGD PMID:19268536, PMID:19268536 RGD:2311716, RGD:2311716 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment IDA
IEP
associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:17967803, PMID:17914354 RGD:10395374, RGD:10395377 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21832210 RGD:5688728 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin ISO associated with Diabetes Mellitus, Experimental;
DNA:snp:promoter:-1125T>G(rs1617640)(human)
RGD PMID:19619913, PMID:19356735, PMID:18458324 RGD:2313832, RGD:2313833, RGD:2313838 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IEP associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney: RGD PMID:10749885 RGD:9685546 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Esr1 estrogen receptor 1 IEP
ISO
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:snps:introns: multiple(human)
RGD PMID:16464734, PMID:18305958 RGD:2314020, RGD:2314005 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G F2 coagulation factor II disease_progression ISO protein:increased expression:plasma (human)
DNA:polymorphism: :20210G>A(human)
RGD PMID:21955218, PMID:14983223, PMID:21574459 RGD:6893574, RGD:2313643, RGD:6893575 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F3 coagulation factor III, tissue factor ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:15004866 RGD:2313863 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp2 fatty acid binding protein 2 ISO RGD PMID:16249461 RGD:1578457 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fas Fas cell surface death receptor ISO
IEP
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney
associated with Diabetes Mellitus, Experimental;protein:increased expression:renal distal tubule (rat)
mRNA:increased expression:kidney
RGD PMID:17851466, PMID:12861046, PMID:18287563 RGD:2315705, RGD:8686421, RGD:2312739 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:kidney RGD PMID:17851466 RGD:2315705 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbn1 fibrillin 1 onset ISO associated with Diabetes Mellitus, Experimental RGD PMID:16395273, PMID:16380460 RGD:7365077, RGD:7365080 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO mRNA:increased expression:kidney RGD PMID:19279131 RGD:2315842 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf21 fibroblast growth factor 21 ISO protein:increased expression:serum: RGD PMID:25625802 RGD:10401920 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgf23 fibroblast growth factor 23 severity IEP mRNA,protein:increased expression:kidney: RGD PMID:23967103 RGD:10044235 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine RGD PMID:15610240 RGD:2313731 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fmod fibromodulin ISO mRNA,protein:increased expression:Kidney Glomerulus
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:decreased expression:kidney cortex
RGD PMID:11259366, PMID:16868749 RGD:2311416, RGD:2311412 NCBI chr13:50,874,886...50,885,503
Ensembl chr13:50,873,605...50,885,563
JBrowse link
G Fn1 fibronectin 1 treatment ISO
IEP
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney cortex:
CTD PMID:24413998, PMID:16301823, PMID:22736507 RGD:7206843, RGD:10402169 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fuca1 alpha-L-fucosidase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;protein:decreased activity;urine RGD PMID:8343614 RGD:2315943 NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP associated with Hypertension RGD PMID:21987533 RGD:10449128 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gas6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12644472, PMID:15619028 RGD:1579938 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 ISO RGD PMID:9519709 RGD:2313353 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP:3' utr RGD PMID:14764791 RGD:2307362 NCBI chr10:35,279,237...35,325,506
Ensembl chr10:35,279,236...35,325,508
JBrowse link
G Ghr growth hormone receptor susceptibility ISO
IEP
IMP
associated with Diabetes Mellitus
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
RGD PMID:10541297, PMID:10990443, PMID:10614635, PMID:15066219 RGD:2307370, RGD:2307368, RGD:2307369, RGD:2307364 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gipr gastric inhibitory polypeptide receptor ISO RGD PMID:19211686 RGD:2306734 NCBI chr 1:80,063,047...80,073,223
Ensembl chr 1:80,063,049...80,073,223
JBrowse link
G Glo1 glyoxalase 1 no_association ISO DNA:SNP:promoter:-7C>T (human) RGD PMID:21738003, PMID:21738003 RGD:7242569, RGD:7242569 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:increased expression:glomerulus
associated with Diabetes Mellitus, Type 1
RGD PMID:17609286, PMID:16249459 RGD:2306609, RGD:11068479 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:decreased expression:serum (human) RGD PMID:17269729 RGD:2312635 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment IEP RGD PMID:23196710 RGD:13792785 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 treatment IEP RGD PMID:23196710 RGD:13792785 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IEP protein:decreased expression:cortex of kidney (rat) RGD PMID:23196710 RGD:13792785 NCBI chr14:81,261,708...81,339,516
Ensembl chr14:81,265,672...81,339,526
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 treatment IEP RGD PMID:23196710 RGD:13792785 NCBI chr17:9,705,917...9,721,921
Ensembl chr17:9,703,453...9,721,574
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IMP RGD PMID:26888388 RGD:13792773 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO
IEP
associated with Diabetes Mellitus, Type 2;protein:decreased activity:kidney
associated with Diabetes Mellitus, Experimental
RGD PMID:23626958, PMID:24947049 RGD:7257582, RGD:10401899 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 no_association ISO associated with Diabetes Mellitus, Type 1;DNA:deletion:cds: (human) RGD PMID:19752172 RGD:7495818 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 disease_progression
no_association
ISO associated with Diabetes Mellitus, Type 2;DNA:deletion:cds (human)
associated with Diabetes Mellitus, Type 1;DNA:deletion:cds (human)
RGD PMID:15927971, PMID:19752172 RGD:2306630, RGD:7495818 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Has2 hyaluronan synthase 2 IEP associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal medulla RGD PMID:18441392 RGD:9588630 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 disease_progression IEP
ISO
protein:increased expression:plasma
associated with Diabetes mellitus, Type 1;
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
RGD PMID:22997966, PMID:20980978, PMID:22015481 RGD:7245497, RGD:7246890, RGD:7245960 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hdac2 histone deacetylase 2 IEP
ISO
mRNA,protein:increased expression:kidney: RGD PMID:24717296, PMID:24717296, PMID:24717296 RGD:9590311, RGD:9590311, RGD:9590311 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac4 histone deacetylase 4 treatment IEP
IMP
ISO
mRNA,protein:increased expression:kidney: RGD PMID:24717296, PMID:24717296, PMID:24717296, PMID:24717296 RGD:9590311, RGD:9590311, RGD:9590311, RGD:9590311 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac5 histone deacetylase 5 IEP
ISO
mRNA,protein:increased expression:kidney: RGD PMID:24717296, PMID:24717296, PMID:24717296 RGD:9590311, RGD:9590311, RGD:9590311 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hfe homeostatic iron regulator ISO associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:15347835 RGD:8694362 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:16340242 RGD:2313567 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IDA
IEP
associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:17967803, PMID:17914354 RGD:10395374, RGD:10395377 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:21849637 RGD:10755581 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IEP mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO associated with Diabetes Mellitus, Type 2 RGD PMID:18518860 RGD:7242747 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO RGD PMID:18518860 RGD:7242747 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney RGD PMID:19301230 RGD:2311449 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:17330940 RGD:7242762 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP
ISO
mRNA,protein:increased expression:glomerulus:
protein:increased expression:glomerulus, podocyte:
RGD PMID:21931298, PMID:21931298 RGD:10402764, RGD:10402764 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP
ISO
associated with Diabetes Mellitus, Experimental;
associated with Diabetes Mellitus Type 2;
RGD PMID:18175064, PMID:12213354 RGD:7257686, RGD:7257687 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO
IDA
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Insulin-Dependent;DNA:SNP: :p.K469E (rs5498) (human)
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney (mouse)
RGD PMID:18299691, PMID:19246972, PMID:18505543, PMID:20447389 RGD:2312766, RGD:2313470, RGD:2313475, RGD:4145414 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma ISO mRNA, protein:increased expression:kidney, T cell RGD PMID:22286547 RGD:6893364 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 ISO
IEP
protein:decreased expression:serum
associated with Diabetes Mellitus, Experimental;protein:decreased expression:serum (rat)
RGD PMID:17194636, PMID:10444029 RGD:2313764, RGD:12904967 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA,protein:increased expression:kidney: RGD PMID:19008912 RGD:10046022 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 IEP
ISO
associated with Diabetes Mellitus, Type 2; mRNA:decreased expression:neural tissue, liver:
associates with Diabetes Mellitus; mRNA:decreased expression:brain:
RGD PMID:9336345, PMID:8764603, PMID:9336345 RGD:5510019, RGD:5510022, RGD:5510019 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO DNA:SNPs RGD PMID:16306374 RGD:1625238 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Il10 interleukin 10 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphisms:promoter:g.-1082G>A, g.-819C>T, g.-592C>A (human) RGD PMID:19031431 RGD:2308943 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta ISO
IDA
associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:22086159, PMID:19769609 RGD:7175266, RGD:7175519 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
no_association
ISO associated with Diabetes Mellitus, Type 2; DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:16174285, PMID:17286233 RGD:6907371, RGD:6909120 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 susceptibility ISO
IDA
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
associated with Diabetes Mellitus, Type1;DNA:polymorphism:promoter:-174G>C(human)
associated with Diabetes Mellitus, Experimental; protein:increased expression:kidney (rat)
RGD PMID:18716362, PMID:19542902, PMID:19052104 RGD:2307282, RGD:7829816, RGD:2307281 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 resistance IDA
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2143390 PMID:7713310 PMID:7987072, PMID:22068113 RGD:6902908 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irs2 insulin receptor substrate 2 ISO mRNA:increased expression:kidney tubule RGD PMID:23617393 RGD:7257702 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Itga2 integrin subunit alpha 2 severity ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:mesangial cell (human) RGD PMID:8989742 RGD:2307420 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Jak2 Janus kinase 2 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kdm6a lysine demethylase 6A ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:kidney (mouse) RGD PMID:23508046 RGD:9587808 NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18630688 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 IDA RGD PMID:21439372 RGD:6893386 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kl Klotho treatment IEP protein:decreased expression:kidney: RGD PMID:24136780 RGD:10403079 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19516248 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 ISO RGD PMID:17272402 RGD:1641794 NCBI chr 1:99,298,965...99,303,048
Ensembl chr 1:99,299,011...99,303,048
JBrowse link
G Klkb1 kallikrein B1 disease_progression ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Kng2 kininogen 2 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :7965C>T (human) RGD PMID:17065357 RGD:2311541 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lamb2 laminin subunit beta 2 IEP RGD PMID:19864299 RGD:7207449 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Lcn2 lipocalin 2 IEP
ISO
protein:increased expression:urine
associated with Diabetes Mellitus,Type 2;protein:increased expression:urine:
RGD PMID:22997966, PMID:22015481 RGD:7245497, RGD:7245960 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lep leptin ISO RGD PMID:22773754 RGD:6907074 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28130181 PMID:29988851 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lmna lamin A/C ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :1908C>T (human) RGD PMID:16117820 RGD:2306095 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase ISO RGD PMID:1789335 RGD:2311543 NCBI chr 1:59,289,392...59,384,540
Ensembl chr 1:59,297,294...59,347,472
Ensembl chr 1:59,297,294...59,347,472
JBrowse link
G Lpl lipoprotein lipase susceptibility ISO RGD PMID:16813599 RGD:2306755 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lta lymphotoxin alpha ISO DNA:polymorphism RGD PMID:18575614 RGD:2313255 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO RGD PMID:19923143 RGD:7243957 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased activity:kidney RGD PMID:19066844 RGD:2311566 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mdk midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:17607302 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mfn2 mitofusin 2 treatment IMP
ISO
IEP
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD PMID:27997345, PMID:27997345, PMID:26123583 RGD:12910740, RGD:11053290 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mir145 microRNA 145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24223694 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mllt3 MLLT3, super elongation complex subunit treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23077601 RGD:9686143 NCBI chr 5:106,103,498...106,202,559
Ensembl chr 5:106,103,407...106,207,126
JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO RGD PMID:21277817 RGD:7241216 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23384615 RGD:13204971 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO protein: decreased expression: glomerulus RGD PMID:9211353 RGD:7241249 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO
IEP
associated with Diabetes Mellitus, Type 2;DNA:repeat:promoter
associated with Diabetes Mellitus, Experimental
RGD PMID:11576356, PMID:23384615 RGD:8547866, RGD:13204971 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility
no_association
ISO associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human) RGD PMID:14737040, PMID:18280442 RGD:6893524, RGD:6893576 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtor mechanistic target of rapamycin kinase susceptibility ISO
IDA
DNA:SNP,haplotype: :rs7212142(human)
associated with Diabetes Mellitus, Experimental
RGD PMID:21606597, PMID:28536139, PMID:23827786 RGD:7245564, RGD:13506787, RGD:10003168 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO Associated with Diabetes Mellitus, Type 1;DNA:SNP:cds:66A>G, (rs1801394) (human) RGD PMID:18774994 RGD:6893652 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link
G Nat2 N-acetyltransferase 2 ISO associated with Diabetes Mellitus, Insulin-Dependent RGD PMID:10591543 RGD:2311598 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 treatment IEP associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney,glomerulus
associated with Diabetes Mellitus, Experimental
RGD PMID:22903132, PMID:22591908 RGD:8552684, RGD:13792578 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment IDA
ISO
IEP
CTD Direct Evidence: therapeutic
associated with Diabetes Mellitus, Experimental
CTD PMID:20103708, PMID:21439372, PMID:23064900 RGD:6893386, RGD:10412718 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos1 nitric oxide synthase 1 treatment IDA
IMP
associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Experimental
RGD PMID:23548923, PMID:10966937 RGD:7257655, RGD:13824991 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility
treatment
no_association
ISO
IEP
associated with Diabetes Mellitus, Type 2;DNA:duplication:intron:IVS4?-?+27 (human)
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD PMID:20042665, PMID:10868974, PMID:29336891, PMID:10741691 RGD:7421530, RGD:13504726, RGD:7421534 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox4 NADPH oxidase 4 IEP
IMP
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:kidney cortex RGD PMID:17511984, PMID:16135519 RGD:2324670, RGD:2324673 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin treatment IEP
ISO
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:decreased expression:kidney (mouse)
RGD PMID:17624267, PMID:21617141, PMID:24173355, PMID:30862474 RGD:38596322, RGD:7241083, RGD:38599008, RGD:38596325 NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559
JBrowse link
G Nppa natriuretic peptide A no_association
disease_progression
ISO
IEP
DNA:polymorphism:intron
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :2238T>C (human)
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:blood
RGD PMID:9681733, PMID:10404802, PMID:15111511, PMID:10381153 RGD:2313593, RGD:7247731, RGD:2313590, RGD:2313592 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:10404802, PMID:16917760 RGD:7247731, RGD:7248603 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:21457706 RGD:11035226 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IMP RGD PMID:20557422 RGD:4891134 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:20621183 RGD:11073737 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pax2 paired box 2 IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney cortex RGD PMID:15149326 RGD:2316747 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO associated with Diabetes Mellitus, Non-Insulin Dependent;mRNA, protein:increased expression:kidney RGD PMID:12808179 RGD:2311649 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO associated with Diabetes Mellitus, Non-Insulin Dependent RGD PMID:15067514 RGD:2311646 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:glomerulus RGD PMID:15042541 RGD:2311655 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pgf placental growth factor disease_progression ISO associated with Diabetes Mellitus, Type 1 RGD PMID:21988672 RGD:6483606 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Plat plasminogen activator, tissue type ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16598198 RGD:2311671 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase IEP mRNA:increased expression:renal glomerulus (rat) RGD PMID:15322501 RGD:1580123 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pon1 paraoxonase 1 no_association
susceptibility
ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus;DNA:missense mutations:cds:p.L55M, p.Q192R (rs854560, rs662) (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
CTD PMID:26884296, PMID:19207863, PMID:24100645, PMID:15270786 RGD:2313266, RGD:8547572, RGD:8547548 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 ISO associated with type 1 diabetes mellitus;DNA:missense mutation:cds:p.C311S (human)
associated with type 2 diabetes mellitus;DNA:polymorphisms:multiple
RGD PMID:11918623, PMID:11206400 RGD:1580218, RGD:2313492 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Postn periostin ISO mRNA,protein:increased expression:kidney: RGD PMID:22167593 RGD:10040972 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO
IMP
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD PMID:28182703, PMID:18780770, PMID:18388116 RGD:2301845, RGD:2301862 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO mRNA:decreased expression:kidney (human)
DNA:polymorphism:exon:p.G482S (human)
RGD PMID:21784897, PMID:19900151 RGD:7242027, RGD:7242045 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prkcb protein kinase C, beta IDA associated with hypertension;protein:increased expression:glomerular mesangium RGD PMID:12540629 RGD:729635 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prmt1 protein arginine methyltransferase 1 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23159951 RGD:9491822 NCBI chr 1:100,971,132...100,980,411
Ensembl chr 1:100,971,273...100,980,340
JBrowse link
G Pros1 protein S severity
treatment
ISO
IEP
associated with diabetes mellitus, experimental
associated with diabetes mellitus, experimental;mRNA, protein:increased expression:kidney, glomerulus
RGD PMID:29511111, PMID:29511111, PMID:29511111, PMID:29511111 RGD:13515131, RGD:13515131, RGD:13515131, RGD:13515131 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Prss1 serine protease 1 ISO protein:increased expression:urine RGD PMID:18428024 RGD:2324899 NCBI chr 4:70,776,046...70,779,249
Ensembl chr 4:70,776,046...70,779,249
JBrowse link
G Prss2 protease, serine, 2 ISO protein:increased expression:urine RGD PMID:18428024 RGD:2324899 NCBI chr 4:70,689,737...70,694,816
Ensembl chr 4:70,689,737...70,694,761
JBrowse link
G Pten phosphatase and tensin homolog IEP protein:decreased expression:kidney cortex, glomerulus RGD PMID:16804083 RGD:2292546 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgds prostaglandin D2 synthase susceptibility ISO RGD PMID:15970590 RGD:1642581 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP associated with Diabetes Mellitus, Experimental RGD PMID:21441310, PMID:17112505 RGD:5135032, RGD:5688268 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone ISO DNA:snps:exon, intron:g.350C>A, g.IVS2+56G>A (rs6256, rs6254) (human) RGD PMID:22777106 RGD:7242744 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17900838 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin IDA RGD PMID:15489960 RGD:1579795 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Retn resistin ISO RGD PMID:21425555 RGD:7207159 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Selp selectin P severity IEP
ISO
associated with Diabetes Mellitus, Experimental;protein:increased expression:kidney, serum
associated with Diabetes Mellitus, Non-Insulin-Dependent
RGD PMID:18471420, PMID:18026823 RGD:2312294, RGD:2312302 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpinb7 serpin family B member 7 ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2;DNA:SNP:intron:rs1720843 (human)
RGD PMID:16443768, PMID:19690890 RGD:7207374, RGD:7207378 NCBI chr13:27,282,456...27,354,775
Ensembl chr13:27,312,498...27,354,052
JBrowse link
G Serpine1 serpin family E member 1 treatment IEP
ISO
IDA
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:renal glomerulus, mesangial cell (rat)
CTD Direct Evidence: marker/mechanism
associate with Diabetes Mellitus, Type 1;protein:increased expression:plasma (human)
CTD PMID:18682491, PMID:15322501, PMID:26712211, PMID:10809802 RGD:1580123, RGD:11073694, RGD:8547711 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf1 serpin family F member 1 treatment IEP
ISO
mRNA, protein:decreased expression:renal cortex, renal medulla (rat)
associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma (human)
human protein in a mouse model
RGD PMID:15616035, PMID:18523656, PMID:23884140 RGD:1359799, RGD:8554896, RGD:8554865 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Slc2a1 solute carrier family 2 member 1 treatment ISO
IEP
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2;DNA:SNP:exon:g.20882C>T (human)
RGD PMID:15745834, PMID:22707888, PMID:26337659 RGD:2312305, RGD:12879861, RGD:12879466 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Smad6 SMAD family member 6 IEP associated with Diabetes Mellitus, Experimental RGD PMID:17437042 RGD:2289036 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphisms: :multiple
human gene in a mouse model
protein:decreased expression:kidney
RGD PMID:17914031, PMID:11522679, PMID:19470681 RGD:2312365, RGD:8655571, RGD:2312361 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24819633, PMID:17192491 RGD:7175540 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 ISO protein:decreased expression:kidney RGD PMID:19470681 RGD:2312361 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP associated with Diabetes Mellitus, Experimental;mRNA, protein:decreased expression:kidney RGD PMID:8569083 RGD:2300072 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:12032186 RGD:1581328 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 ISO
IEP
associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:kidney
RGD PMID:16936198, PMID:17961514, PMID:17961514, PMID:18613221, PMID:16046298 RGD:2308815, RGD:2308811, RGD:2308811, RGD:2308806, RGD:1581418 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO associated with Diabetes Mellitus, Insulin-Dependent;mRNA:increased expression:kidney
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:kidney
RGD PMID:16936198, PMID:16046298 RGD:2308815, RGD:1581418 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:22745068 RGD:10403082 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP (human) RGD PMID:19506043 RGD:6906926 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tf transferrin IDA RGD PMID:23468095 RGD:7244196 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO
IEP
mRNA:increased expression:glomerulus
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental
CTD PMID:18682491 PMID:19960420, PMID:19211686, PMID:24074026 RGD:2306734, RGD:7394855 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbi transforming growth factor, beta induced IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18682491, PMID:12911551 RGD:1304421 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496156 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 IEP protein:decreased expression:glomerulus (rat) RGD PMID:15153551 RGD:1599409 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Thbs1 thrombospondin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17878288 RGD:2317941 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IEP mRNA:increased expression:kidney RGD PMID:17491697 RGD:2290407 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tinag tubulointerstitial nephritis antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr 8:84,122,113...84,320,714
Ensembl chr 8:84,279,229...84,320,746
JBrowse link
G Tlr2 toll-like receptor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:21617141 RGD:7241083 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 ISO associated with Diabetes Mellitus, Experimental RGD PMID:22021706 RGD:7207902 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor IDA
IEP
ISO
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Experimental;protein:increased expression:urine
RGD PMID:16336586, PMID:12969138, PMID:21441310, PMID:16141456 RGD:1580208, RGD:1580296, RGD:5135032, RGD:1580311 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip1 TNF alpha induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20665664 NCBI chr10:65,791,002...65,805,693
Ensembl chr10:65,791,003...65,805,693
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B disease_progression
treatment
ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 2
RGD PMID:18719882, PMID:20727867 RGD:7205493, RGD:7205514 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO associated with Diabetes Mellitus, Type 2
associated with Diabetes Mellitus, Type 1;protein:increased expression:serum
RGD PMID:22042131, PMID:19073786 RGD:7245547, RGD:2311357 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B onset ISO associated with Diabetes Mellitus, Type 1
associated with Diabetes Mellitus, Type 1;protein:increased expression:serum
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
RGD PMID:22266664, PMID:19073786, PMID:16408124 RGD:7245476, RGD:2311357, RGD:7245529 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO protein:increased expression:kidney RGD PMID:18287563 RGD:2312739 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp53 tumor protein p53 IEP associated with Diabetes Mellitus, Experimental RGD PMID:17901943 RGD:2290561 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:26097534 RGD:11535148 NCBI chr 9:9,689,214...9,702,353
Ensembl chr 9:9,689,475...9,702,306
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 IEP mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:22673147 RGD:7247584 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535
JBrowse link
G Txnip thioredoxin interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17582205 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:urine (human) RGD PMID:17634209 RGD:2311211 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Ucp1 uncoupling protein 1 no_association ISO DNA:SNP: :-3826A>G (human) RGD PMID:15120704 RGD:7247625 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ucp2 uncoupling protein 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22848482 RGD:7175295 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Uts2 urotensin 2 disease_progression ISO
IEP
mRNA:increased expression:kidney
associated with Diabetes Mellitus, Type 2;protein:increased expression:urine
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
RGD PMID:15492948, PMID:15476950, PMID:18796544 RGD:2306805, RGD:2306806, RGD:2306786 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145
JBrowse link
G Uts2r urotensin 2 receptor ISO
IEP
mRNA:increased expression:kidney
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:kidney
RGD PMID:15492948, PMID:18796544 RGD:2306805, RGD:2306786 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked ISO associated with Diabetes Mellitus, Type 1;protein:increased expression:kidney (mouse) RGD PMID:23508046 RGD:9587808 NCBI chr  Y:1,065,274...1,206,127
Ensembl chr  Y:989,240...1,206,096
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP
ISO
protein:increased expression:kidney
associated with Diabetes Mellitus,Type 1;protein:increased expression:plasma:
RGD PMID:23303408, PMID:20138682 RGD:7240523, RGD:7241237 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vdac1 voltage-dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdac2 voltage-dependent anion channel 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19634143 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
CTD PMID:18630688, PMID:15610240 RGD:2313731 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vtn vitronectin IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:glomerulus RGD PMID:11728964 RGD:10003096 NCBI chr10:65,767,960...65,771,040
Ensembl chr10:65,767,053...65,771,038
JBrowse link
G Xdh xanthine dehydrogenase treatment IDA
ISO
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 2
RGD PMID:22302365, PMID:19458127 RGD:7247644, RGD:7247651 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xylt1 xylosyltransferase 1 ISO associated with Diabetes Mellitus, Insulin-Dependent;DNA:missense mutation:cds:p.A115S (human) RGD PMID:17003309 RGD:2313138 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
JBrowse link
diabetic neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2b adrenoceptor alpha 2B ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism (human) RGD PMID:17516297 RGD:2313542 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:22171162 RGD:8695979 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B susceptibility IDA
ISO
associated with Diabetes Mellitus, Experimental
associated with Diabetes Mellitus, Type 1;DNA:repeat:promoter:g.(CA)n (human)
RGD PMID:16900242, PMID:9489533 RGD:1626089, RGD:8548642 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:15318096 RGD:2311150 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:20724598 RGD:5509623 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:24288572 RGD:10053667 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bdkrb1 bradykinin receptor B1 IMP RGD PMID:20587056 RGD:5129222 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdnf brain-derived neurotrophic factor IMP associated with Diabetes Mellitus, Experimental RGD PMID:20557422 RGD:4891134 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:25824552 RGD:11561957 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Casp3 caspase 3 IEP
ISO
associated with Diabetes Mellitus, Experimental;protein:increased expresssion:sciatic nerve
CTD Direct Evidence: marker/mechanism
CTD PMID:12502508, PMID:19555701 RGD:2311441 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10780678 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:19675140 RGD:8661787 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO associated with Diabetes Mellitus;protein:increased expression:serum RGD PMID:19276232 RGD:2307060 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd63 Cd63 molecule ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:platelet RGD PMID:10547212 RGD:2314203 NCBI chr 7:3,320,250...3,335,583
Ensembl chr 7:3,320,103...3,335,582
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20624991 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Cnr1 cannabinoid receptor 1 IDA associated with Diabetes Mellitus, Experimental RGD PMID:18810243 RGD:2314631 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Epo erythropoietin ISO associated with Diabetes Mellitus, Experimental; RGD PMID:14718663 RGD:2313898 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Insulin-Dependent; protein:altered expression:plasma (human) RGD PMID:10468085 RGD:2312401 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:16644707 RGD:2315860 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus,Insulin-Dependent;protein:increased activity:serum RGD PMID:11311965 RGD:2315614 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO associated with Diabetes Mellitus, Experimental RGD PMID:19733151 RGD:2313744 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Grm5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19840219 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392
JBrowse link
G Hgf hepatocyte growth factor ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: therapeutic
CTD PMID:26000320, PMID:15734864 RGD:2313570 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hhip Hedgehog-interacting protein IEP RGD PMID:19515211 RGD:11552601 NCBI chr19:31,525,134...31,614,487
Ensembl chr19:31,524,671...31,614,246
JBrowse link
G Ifng interferon gamma ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :874A>T (human) RGD PMID:19608431 RGD:2311489 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 treatment IMP
ISO
associated with Diabetes Mellitus, Experimental
protein:decreased expression:serum
RGD PMID:19264110, PMID:18545223, PMID:17194636 RGD:2306687, RGD:8549454, RGD:2313764 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il1b interleukin 1 beta treatment IEP RGD PMID:23280817 RGD:7401217 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Insr insulin receptor IDA
ISO
associated with Diabetes Mellitus, Experimental;protein:decreased phosphorylation:sciatic nerve
CTD Direct Evidence: marker/mechanism
CTD PMID:18331706, PMID:18331706 RGD:2307344 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24263156 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:cerebellum, Purkinje cell RGD PMID:24810053 RGD:13462056 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Mapk14 mitogen activated protein kinase 14 IDA associated with Diabetes Mellitus, Experimental RGD PMID:18579738 RGD:2311567 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mbp myelin basic protein IEP associated with Diabetes Mellitus, Experimental; protein:decreased expression:sciatic nerve: RGD PMID:23735240 RGD:7327194 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mme membrane metallo-endopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20148083 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20213226 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20213226 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpz myelin protein zero treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:22158827 RGD:9685782 NCBI chr13:89,524,204...89,530,070
Ensembl chr13:89,524,329...89,530,068
JBrowse link
G Ngf nerve growth factor IEP mRNA,protein:decreased expression:sciatic nerve RGD PMID:12469361 RGD:5508379 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor IEP mRNA,protein:decreased expression:dorsal root ganglia (GK/KyoSwe) RGD PMID:12469361 RGD:5508379 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18802679 RGD:2313218 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nrg1 neuregulin 1 treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:24288572 RGD:10053667 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ntf3 neurotrophin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11779407 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP mRNA,protein:decreased expression:dorsal root ganglia RGD PMID:12469361 RGD:5508379 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:17976390, PMID:21978940 RGD:5510012, RGD:5683915 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pgf placental growth factor ISO associated with Diabetes Mellitus, Experimental RGD PMID:21056561 RGD:6483583 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Plat plasminogen activator, tissue type ISO RGD PMID:17636064 RGD:2311667 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
IEP
mRNA, protein:increased expression:peripheral nerve RGD PMID:17720896, PMID:21951301 RGD:1642588, RGD:5508311 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Retn resistin ISO associated with Diabetes Mellitus, Type 2 RGD PMID:17919381 RGD:7207161 NCBI chr12:2,201,909...2,203,649
Ensembl&