CD34 (CD34 molecule) - Rat Genome Database

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Gene: CD34 (CD34 molecule) Pan paniscus
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Symbol: CD34
Name: CD34 molecule
RGD ID: 11725421
Description: ENCODES a protein that exhibits carbohydrate binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); sulfate binding (ortholog); INVOLVED IN cell motility (ortholog); cell-cell adhesion (ortholog); endothelial cell proliferation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); diabetic retinopathy (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN apical plasma membrane (ortholog); basal plasma membrane (ortholog); cell periphery (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: hematopoietic progenitor cell antigen CD34
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11188,272,551 - 188,297,384 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1188,272,551 - 188,297,384 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01183,459,028 - 183,489,583 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell motility  (ISO)
cell-cell adhesion  (ISO)
endothelial cell proliferation  (ISO)
endothelium development  (ISO)
extracellular exosome assembly  (ISO)
glomerular endothelium development  (ISO)
glomerular filtration  (ISO)
hematopoietic stem cell proliferation  (ISO)
hemopoiesis  (ISO)
leukocyte migration  (ISO)
mesangial cell-matrix adhesion  (ISO)
metanephric glomerular mesangial cell differentiation  (ISO)
negative regulation of blood coagulation  (ISO)
negative regulation of cellular response to heat  (ISO)
negative regulation of cellular response to hypoxia  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of neuron death  (ISO)
negative regulation of nitric oxide biosynthetic process  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
paracrine signaling  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of glial cell-derived neurotrophic factor production  (ISO)
positive regulation of granulocyte colony-stimulating factor production  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of odontogenesis  (ISO)
positive regulation of transforming growth factor beta production  (ISO)
positive regulation of vasculogenesis  (ISO)
regulation of blood pressure  (ISO)
signal transduction  (ISO)
stem cell proliferation  (ISO)
tissue homeostasis  (ISO)
transdifferentiation  (ISO)
vascular wound healing  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
CD34
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11188,272,551 - 188,297,384 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1188,272,551 - 188,297,384 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01183,459,028 - 183,489,583 (-)NCBIMhudiblu_PPA_v0panPan3
CD34
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1207,880,972 - 207,911,402 (-)EnsemblGRCh38hg38GRCh38
GRCh381207,880,972 - 207,911,125 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371208,054,317 - 208,084,470 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361206,126,506 - 206,151,306 (-)NCBINCBI36hg18NCBI36
Build 341204,448,278 - 204,472,910NCBI
Celera1181,290,338 - 181,315,139 (-)NCBI
Cytogenetic Map1q32.2NCBI
HuRef1178,734,078 - 178,758,883 (-)NCBIHuRef
CHM1_11209,332,232 - 209,357,037 (-)NCBICHM1_1
Cd34
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,621,129 - 194,643,600 (+)NCBIGRCm39mm39
GRCm39 Ensembl1194,621,127 - 194,643,587 (+)Ensembl
GRCm381194,938,821 - 194,961,292 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,938,819 - 194,961,279 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,765,015 - 196,787,486 (+)NCBIGRCm37mm9NCBIm37
MGSCv361196,639,632 - 196,662,003 (+)NCBImm8
Celera1201,838,605 - 201,861,076 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map198.38NCBI
Cd34
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.213106,480,074 - 106,499,462 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl13106,480,043 - 106,499,832 (+)Ensembl
Rnor_6.013113,691,842 - 113,711,259 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13113,691,932 - 113,711,647 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013118,531,837 - 118,551,216 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413110,877,594 - 110,896,722 (+)NCBIRGSC3.4rn4RGSC3.4
Celera13105,904,553 - 105,923,681 (+)NCBICelera
Cytogenetic Map13q27NCBI
Cd34
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540643,117,816 - 43,130,463 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540643,116,688 - 43,130,405 (-)NCBIChiLan1.0ChiLan1.0
CD34
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.176,734,363 - 6,747,991 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl76,734,363 - 6,748,581 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha76,297,083 - 6,321,394 (-)NCBI
ROS_Cfam_1.076,422,992 - 6,447,293 (-)NCBI
UMICH_Zoey_3.176,355,774 - 6,380,048 (-)NCBI
UNSW_CanFamBas_1.076,458,250 - 6,482,488 (-)NCBI
UU_Cfam_GSD_1.076,499,295 - 6,523,438 (-)NCBI
Cd34
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934467,790,294 - 67,811,581 (+)NCBI
SpeTri2.0NW_0049365575,030,788 - 5,051,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD34
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9134,913,121 - 134,937,762 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19134,912,793 - 134,937,763 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29148,445,995 - 148,470,638 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CD34
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12521,534,969 - 21,559,951 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2521,534,983 - 21,561,215 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605522,145,967 - 22,170,846 (+)NCBIVero_WHO_p1.0
Cd34
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248073,936,043 - 3,958,274 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054639   ⟹   ENSPPAP00000031774
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,272,551 - 188,297,384 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054650   ⟹   ENSPPAP00000031785
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,273,756 - 188,275,854 (-)Ensembl
RefSeq Acc Id: XM_003831202   ⟹   XP_003831250
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11188,272,551 - 188,297,384 (-)NCBI
Mhudiblu_PPA_v01183,459,028 - 183,489,583 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003831203   ⟹   XP_003831251
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11188,272,551 - 188,297,384 (-)NCBI
Mhudiblu_PPA_v01183,459,028 - 183,489,535 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003831250 (Get FASTA)   NCBI Sequence Viewer  
  XP_003831251 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003831250   ⟸   XM_003831202
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003831251   ⟸   XM_003831203
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000031774   ⟸   ENSPPAT00000054639
RefSeq Acc Id: ENSPPAP00000031785   ⟸   ENSPPAT00000054650


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038798 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000031774 ENTREZGENE
NCBI Gene CD34 ENTREZGENE