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Gene: BMP7 (bone morphogenetic protein 7) Pan paniscus

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Symbol:

BMP7

Name:

bone morphogenetic protein 7 (Ensembl:bone morphotic protein 7)

RGD ID:

11830836

Description:

ENCODES a protein that exhibits heparin binding (ortholog); INVOLVED IN kidney development (ortholog); osteoblast differentiation (ortholog); regulation of phosphorylation (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; ASSOCIATED WITH acute kidney tubular necrosis (ortholog); Acute Otitis Media (ortholog); atrial heart septal defect 8 (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog); vesicle (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	62,920,305 - 63,017,237 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	62,913,422 - 63,010,356 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	53,509,484 - 53,606,889 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	54,788,974 - 54,885,015 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	54,788,974 - 54,885,021 (-)	Ensembl			panPan2	panpan1.1

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney tubular necrosis (ISO)

Acute Otitis Media (ISO)

atrial heart septal defect 8 (ISO)

Bone Fractures (ISO)

bone resorption disease (ISO)

breast cancer (ISO)

CAKUT (ISO)

Congenital Heart Defects, Multiple Types, 4 (ISO)

Diabetic Nephropathies (ISO)

endometriosis (ISO)

Experimental Liver Cirrhosis (ISO)

Femoral Fractures (ISO)

Gliosis (ISO)

kidney disease (ISO)

Neoplasm Metastasis (ISO)

nephroblastoma (ISO)

nephrotic syndrome type 12 (ISO)

obstructive sleep apnea (ISO)

osteoarthritis (ISO)

ovarian carcinoma (ISO)

prostate cancer (ISO)

Prostatic Neoplasms (ISO)

Pulmonary Arterial Hypertension (ISO)

pulmonary fibrosis (ISO)

pyelonephritis (ISO)

renal cell carcinoma (ISO)

scimitar syndrome (ISO)

Stomach Neoplasms (ISO)

tetralogy of Fallot (ISO)

Tibial Fractures (ISO)

Ventricular Septal Defect 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

allantois development (IEA)

ameloblast differentiation (IEA)

anatomical structure formation involved in morphogenesis (IEA)

animal organ morphogenesis (IEA)

axon guidance (IEA)

BMP signaling pathway (IEA)

branching involved in salivary gland morphogenesis (IEA)

branching morphogenesis of an epithelial tube (IEA)

camera-type eye morphogenesis (IEA)

cardiac muscle tissue development (IEA)

cardiac septum morphogenesis (IEA)

cartilage development (IEA)

cell development (IEA)

cell differentiation (IEA)

cell population proliferation (IEA)

cell-cell adhesion (IEA)

cellular response to BMP stimulus (IEA)

chorio-allantoic fusion (IEA)

embryonic camera-type eye morphogenesis (IEA)

embryonic limb morphogenesis (IEA)

embryonic pattern specification (IEA)

embryonic skeletal joint morphogenesis (IEA)

endocardial cushion formation (IEA)

epithelial cell differentiation (IEA)

eye development (IEA)

heart trabecula morphogenesis (IEA)

hindbrain development (IEA)

kidney development (IEA,ISO)

mesenchymal cell apoptotic process involved in nephron morphogenesis (IEA)

mesenchymal cell differentiation (IEA)

mesenchyme development (IEA)

mesoderm formation (IEA)

mesonephros development (IEA)

metanephric mesenchymal cell proliferation involved in metanephros development (IEA)

metanephric mesenchyme morphogenesis (IEA)

metanephros development (IEA)

monocyte aggregation (IEA)

negative regulation of cell cycle (IEA)

negative regulation of cell population proliferation (IEA)

negative regulation of DNA-templated transcription (IEA)

negative regulation of glomerular mesangial cell proliferation (IEA)

negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (IEA)

negative regulation of mitotic nuclear division (IEA)

negative regulation of neurogenesis (IEA)

negative regulation of neuron differentiation (IEA)

negative regulation of Notch signaling pathway (IEA)

negative regulation of prostatic bud formation (IEA)

nephrogenic mesenchyme morphogenesis (IEA)

neural fold elevation formation (IEA)

neuron projection morphogenesis (IEA)

odontogenesis of dentin-containing tooth (IEA)

ossification (IEA)

osteoblast differentiation (IEA,ISO)

pattern specification process (IEA)

pericardium morphogenesis (IEA)

pharyngeal system development (IEA)

positive regulation of apoptotic process (IEA)

positive regulation of bone mineralization (IEA)

positive regulation of brown fat cell differentiation (IEA)

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis (IEA)

positive regulation of cell differentiation (IEA)

positive regulation of dendrite development (IEA)

positive regulation of DNA-templated transcription (IEA)

positive regulation of epithelial cell differentiation (IEA)

positive regulation of epithelial to mesenchymal transition (IEA)

positive regulation of gene expression (IEA)

positive regulation of heterotypic cell-cell adhesion (IEA)

positive regulation of hyaluranon cable assembly (IEA)

positive regulation of multicellular organismal process (IEA)

positive regulation of neuron differentiation (IEA)

positive regulation of osteoblast differentiation (IEA)

positive regulation of SMAD protein signal transduction (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

regulation of branching involved in prostate gland morphogenesis (IEA)

regulation of multicellular organismal development (IEA)

regulation of phosphorylation (ISO)

response to estradiol (ISO)

response to peptide hormone (ISO)

response to vitamin D (ISO)

salivary gland morphogenesis (IEA)

skeletal system development (IEA)

tube morphogenesis (IEA)

ureteric bud development (IEA)

Cellular Component

extracellular matrix (ISO)

extracellular region (IEA)

extracellular space (IEA,ISO)

vesicle (ISO)

Molecular Function

BMP receptor binding (IEA)

cytokine activity (IEA)

growth factor activity (IEA)

heparin binding (ISO)

protein binding (ISO)

protein serine/threonine kinase activator activity (IEA)

receptor ligand activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Bone morphogenetic proteins signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

BMP7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	62,920,305 - 63,017,237 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	62,913,422 - 63,010,356 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	53,509,484 - 53,606,889 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	54,788,974 - 54,885,015 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	54,788,974 - 54,885,021 (-)	Ensembl			panPan2	panpan1.1

BMP7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	57,168,753 - 57,266,641 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	57,168,753 - 57,266,641 (-)	Ensembl			hg38	GRCh38
GRCh37	20	55,743,809 - 55,841,697 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	55,178,962 - 55,274,708 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	55,178,961 - 55,274,708	NCBI
Celera	20	52,484,025 - 52,581,945 (-)	NCBI		Celera
Cytogenetic Map	20	q13.31	NCBI
HuRef	20	52,525,580 - 52,623,004 (-)	NCBI		HuRef
CHM1_1	20	55,645,001 - 55,742,816 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	58,946,552 - 59,044,382 (-)	NCBI		T2T-CHM13v2.0

Bmp7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	172,709,805 - 172,782,114 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	172,709,805 - 172,782,114 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	172,868,012 - 172,940,321 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	172,868,012 - 172,940,321 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	172,695,187 - 172,765,794 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	172,512,625 - 172,583,232 (-)	NCBI		MGSCv36	mm8
Celera	2	178,834,089 - 178,904,564 (-)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	95.54	NCBI

Bmp7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	182,059,318 - 182,135,273 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	182,052,337 - 182,135,137 (-)	Ensembl				GRCr8
mRatBN7.2	3	161,639,915 - 161,716,938 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,516,462 - 161,716,788 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	165,452,682 - 165,528,533 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	173,951,623 - 174,027,477 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,693,437 - 171,769,286 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	170,879,972 - 170,955,820 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	170,879,973 - 170,955,399 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	176,945,362 - 177,020,745 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	163,723,429 - 163,799,567 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	160,834,683 - 160,910,334 (-)	NCBI		Celera
RGSC_v3.1	3	163,630,250 - 163,704,848 (-)	NCBI
Cytogenetic Map	3	q42	NCBI

Bmp7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	2,153,170 - 2,235,795 (+)	Ensembl
ChiLan1.0	NW_004955445	2,154,057 - 2,235,594 (+)	NCBI	ChiLan1.0	ChiLan1.0

BMP7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	42,203,183 - 42,294,105 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	42,204,823 - 42,294,653 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	41,452,207 - 41,541,996 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	43,068,237 - 43,159,868 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	43,069,877 - 43,159,842 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	42,155,146 - 42,244,886 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	42,294,769 - 42,384,624 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	42,952,879 - 43,042,732 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Bmp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	183,162,668 - 183,234,253 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	71,920 - 143,940 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	71,965 - 143,940 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BMP7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	57,584,956 - 57,675,986 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	57,567,770 - 57,676,516 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	64,737,755 - 64,840,710 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BMP7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	6,856,396 - 6,954,948 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	6,856,453 - 6,954,944 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	54,918,476 - 55,017,287 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bmp7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	23,658,004 - 23,737,742 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	23,658,214 - 23,743,227 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003806158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000041671 ⟹ ENSPPAP00000018925

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	20	54,788,974 - 54,885,021 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000041679 ⟹ ENSPPAP00000018932

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	20	54,791,175 - 54,885,006 (-)	Ensembl

RefSeq Acc Id:

XM_003806158 ⟹ XP_003806206

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	21	62,920,305 - 63,017,237 (-)	NCBI
NHGRI_mPanPan1	20	62,913,422 - 63,010,356 (-)	NCBI
Mhudiblu_PPA_v0	20	53,509,484 - 53,606,889 (-)	NCBI
PanPan1.1	20	54,788,974 - 54,885,015 (-)	NCBI

Sequence:

show sequence

GCCGGCGCGATGCACGTGCGCTCACTGCGAGCTGCGGCGCCGCACAGCTTCGTGGCGCTCTGGG
CACCCCTGTTCCTGCTGCGCTCCGCCCTGGCCGACTTCAGCCTGGACAACGAGGTGCACTCGAG
CTTCATCCACCGGCGCCTCCGCAGCCAGGAGCGGCGGGAGATGCAGCGCGAGATCCTCTCCATT
TTGGGCTTGCCCCACCGCCCGCGCCCGCACCTCCAGGGCAAGCACAACTCGGCACCCATGTTCA
TGCTGGACCTGTACAACGCCATGGCGGTGGAGGAGGGCGGCGGGCCCGGCGGCCAGGGCTTCTC
CTACCCCTACAAGGCCGTCTTCAGTACCCAGGGCCCCCCTCTGGCCAGCCTGCAAGATAGCCAT
TTCCTCACCGACGCCGACATGGTCATGAGCTTCGTCAACCTCGTGGAACATGACAAGGAATTCT
TCCACCCACGCTACCACCATCGAGAGTTCCGGTTTGATCTTTCCAAGATCCCAGAAGGGGAAGC
TGTCACGGCAGCCGAATTCCGGATCTACAAGGACTACATCCGGGAACGCTTCGACAATGAGACG
TTCCGGATCAGCGTTTATCAGGTGCTCCAGGAGCACTTGGGCAGGGAATCGGATCTCTTCCTGC
TCGACAGCCGTACCCTCTGGGCCTCGGAGGAGGGCTGGCTGGTGTTTGACATCACAGCCACCAG
CAACCACTGGGTGGTCAATCCACGGCACAACCTGGGCCTGCAGCTCTCGGTGGAGACGCTGGAT
GGGCAGAGCATCAACCCCAAGTTGGCGGGCCTGATTGGGCGGCACGGGCCCCAGAACAAGCAGC
CCTTCATGGTGGCTTTCTTCAAGGCCACAGAGGTCCACTTCCGCAGCATCCGGTCCACGGGGAG
CAAACAGCGCAGCCAGAACCGCTCCAAGACGCCCAAGAACCAGGAAGCCCTGCGGATGGCCAAC
GTGGCAGAGAACAGCAGCAGCGACCAGAGGCAGGCCTGTAAGAAGCACGAGCTGTATGTCAGCT
TCCGAGACCTGGGCTGGCAGGACTGGATCATCGCGCCCGAAGGCTACGCCGCCTACTACTGTGA
GGGGGAGTGTGCCTTCCCTCTGAACTCCTACATGAACGCCACCAACCACGCCATCGTGCAGACG
CTGGTCCACTTCATCAACCCGGAAACGGTGCCCAAGCCCTGCTGTGCGCCCACGCAGCTCAATG
CCATCTCCGTCCTCTACTTCGATGACAGCTCCAACGTCATCCTGAAGAAATACAGAAACATGGT
GGTCCGGGCCTGTGGCTGCCACTAGCTCCTCCGAGAATTCAGACCCTTTGGGGCCAAGTTTTTC
TGGATCCTCCATTGCTCGCCTTGGCCAGGAACCAGCAGACCAACTGCCTTTTGTGAGACCTTCC
CCTCCCTATCCCCAACTTTAAAGGTGTAAGAGTATTAGGAAACATGAGCAGCATATGGCTTTTG
ATCAGTTTTTCAGTGGCAGCATCCAATGAACAAGATCCTACAAGCTGTGCAGGCAAAACCTAGC
AGGAAAAAAAACACGCATAAAGAAAAATGGCCGGGCCAGGTCATTGGCTGGGAAGTCTCAGCCA
TGCACGGACTCGTTTCCAGAGGTAATTATGAGCGCCCGCCAGCCAGGCCACCCAGCCGTGGGAG
GAAGGGGGCGTGGTAAGGGGTGGGCACATTGGTGTCTGTGCGAAAGGAAAATTGACCCAGAAGT
TCCTGTAATAAATGTCACAATAAAACGAATGAATGAAAATGGTTAGGACGTTACAGATATATTT
TCCTAAACAATTTATCCCCATTTCTCGGTTTATCCTGATGCGTAAACAGAAGCTGTGTCAAGTG
GAGGGCGGGGAGGTCCCTCTCCATTCCCTACAGTTTTCATTCTGAGGCTTGCAGAGGCCCAGTG
TTTACCGAGGTTTGCCCAAATCCAAGATCTAGTGGGAGGGGAAAGAGCAAATGTCTGCTCCGAG
GAGGGCGGTGTGTTGATCTTTGGAGGAAAAATATGTTCTGTTGTTCAGCTGGATTTGCAGTGGC
AGAAATGAAACTAGGTGTGTGAAATACCCGTAGACGTTTGGGATTGGCTTTTCACCTCGCCCCA
GTGGTAGTAAATCCATGTGAAATTGCAGAGGGGACAAGGACAGCAAGTAGGATGGAACTTGCAA
CTCAACCCTGTTGTTAAGAAGCACCAATGGGCCGGGCACAGTAGCTGCCACCTGTAATCCCAGC
ACTTCGGGAGGCTGAGGTGGGCGGATCATTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACA
TGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCACGCACCTGTAA
TCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTG
AGCCAAGATCGTCCCACTGCACTCCAGCTTGGGTGACAAAACAAGACTCCATCTCAAAAGAAAA
AAACAGCACCAATGAAGCCTAGTTCTCCACGGGAGTGTGGTGAGCAGGAGCACTGCACATCCCC
CCAGTGGACCCTCTGGTCTTTGTCTGCAGTGGCATTCCAAGGCTGGGCCCTGGCAAGGGCACCC
GTGGCTGTCTCTTCATTTGCAGACCCTGATCAGAAGTCTCTGCAAACAAATTTGCTCCTTGAAT
TAAGGGGGAGATGGCATAATAGGAGGTCTGATGGGTGCAGGATGTGCTGGACTTACATTGCAAA
TAGAAGCCTTGTTGAGGGTGACATCCTAACCAAGTGTCCCGATTTGGAGGTGGCATTTCTGACG
TGGCTCTTGGTGTAAGCCTGCCTTGCCTTGGCTGGTGAGTCCCATAAATAGTATGCACCCAGCC
TCCGGCCACAAACACAAGGCCTCGGGGAGGGCTAGACTGTCTGCAAACGTTTTCTGCATCTGTG
AAGAAAACAAGGTGATCCAAAACTGTGGCCATGTGGAACCCGGTCTTGTGGGGGACTGTTTCTC
CATCTTGACTCAGACAGTTCCTGGAAACACCAGGGCTCTGTTTTTATTTTCTTTGATGTTTTTC
TTCTTTAGTAGCTTGGGCTGCAGCCTCCACTCTCTAGTCACTGGGGAGGAGTATTTTTTGTTAT
GTTTGGTTTCATTTGCTGGCAGAGCTGGGGCTTTTTGTGTGATCCCTCTTGGTGTGAGTTTTCT
GACCCAACCAGCCTCTGGTTAGCATCATTTGTACATTTAAACCTGTAAATAGTTGTTACAAAGC
AAAGAGATTATTTATTTCCATCCAAAGCTCTTTTGAACACCCCCCCCCCTTTAATCCCTCGTTC
AGGACGATGAGCTTGCTTTCCTTCAACCTGTTTGTTTTCTTATTTAAGACTATTTATTAATGGT
TGGACCAATGTACTCACGGCTGTTGCGTCGAGCAGTCCTTAGTGAAAATTCTGTATAAATAGAC
AAAATAAAAAGGGTTTGACTTTGCAATAAAAGGAGACGTTTGGTTCTGGC

hide sequence

Protein Sequences


Protein RefSeqs	XP_003806206	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000018925.1
	ENSPPAP00000018932.1
	ENSPPAP00050014775

RefSeq Acc Id:

XP_003806206 ⟸ XM_003806158

- UniProtKB:

A0A2R9AT21 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGL
PHRPRPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLT
DADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFDNETFRI
SVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQS
INPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAE
NSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVH
FINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH

hide sequence

Ensembl Acc Id:

ENSPPAP00000018932 ⟸ ENSPPAT00000041679

Ensembl Acc Id:

ENSPPAP00000018925 ⟸ ENSPPAT00000041671

Protein Domains

TGF-beta family profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000032623	Ensembl, UniProtKB/TrEMBL
	ENSPPAG00050011278	ENTREZGENE
Ensembl Transcript	ENSPPAT00000041671.1	UniProtKB/TrEMBL
	ENSPPAT00000041679.1	UniProtKB/TrEMBL
	ENSPPAT00050023642	ENTREZGENE
Gene3D-CATH	2.10.90.10	UniProtKB/TrEMBL
	2.60.120.970	UniProtKB/TrEMBL
InterPro	Cystine-knot_cytokine	UniProtKB/TrEMBL
	TGF-b_C	UniProtKB/TrEMBL
	TGF-b_propeptide	UniProtKB/TrEMBL
	TGF-beta-rel	UniProtKB/TrEMBL
	TGFb_CS	UniProtKB/TrEMBL
KEGG Report	pps:100979629	UniProtKB/TrEMBL
NCBI Gene	BMP7	ENTREZGENE
PANTHER	BONE MORPHOGENETIC PROTEIN 7	UniProtKB/TrEMBL
	PTHR11848	UniProtKB/TrEMBL
Pfam	TGF_beta	UniProtKB/TrEMBL
	TGFb_propeptide	UniProtKB/TrEMBL
PRINTS	INHIBINA	UniProtKB/TrEMBL
PROSITE	TGF_BETA_1	UniProtKB/TrEMBL
	TGF_BETA_2	UniProtKB/TrEMBL
SMART	TGFB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57501	UniProtKB/TrEMBL
UniProt	A0A2R9ANI4_PANPA	UniProtKB/TrEMBL
	A0A2R9AT21	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Annotations - PID (archival)