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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ranitidine
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Accession:CHEBI:8776 term browser browse the term
Definition:A member of the class of furans used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease.
Synonyms:exact_synonym: (E)-N-{2-[({5-[(dimethylamino)methyl]-2-furyl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine
 related_synonym: Formula=C13H22N4O3S;   InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+;   InChIKey=VMXUWOKSQNHOCA-UKTHLTGXSA-N;   SMILES=CN\\C(NCCSCc1ccc(CN(C)C)o1)=C/[N+]([O-])=O;   ranitidina;   ranitidinum
 xref: Beilstein:4327819;   CAS:66357-35-5;   DrugBank:DB00863;   HMDB:HMDB0001930;   KEGG:D00422
 xref_mesh: MESH:D011899
 xref: PMID:18609122;   PMID:19694603;   Patent:FR2384765;   Patent:US4128658;   Reaxys:4327819;   Wikipedia:Ranitidine


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ranitidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO
EXP		 Ranitidine binds to and results in decreased activity of ACHE protein; Ranitidine inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]
Ranitidine affects the reaction [Paraoxon results in decreased activity of ACHE protein]		 CTD PMID:15669026 PMID:15669039 PMID:16193528 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ackr3 atypical chemokine receptor 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ACKR3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ACKR3 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ACKR3 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ADAMTS1 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ADAMTS1 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ADAMTS1 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Alb albumin multiple interactions EXP [Ranitidine co-treated with Diclofenac] results in decreased expression of ALB protein; Quercetin inhibits the reaction [[Ranitidine co-treated with Diclofenac] results in decreased expression of ALB protein] CTD PMID:28400101 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ALDOA mRNA CTD PMID:16415329 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Amotl2 angiomotin like 2 multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in increased expression of AMOTL2 mRNA] CTD PMID:16415329 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910 		JBrowse link
G Arhgef11 Rho guanine nucleotide exchange factor 11 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ARHGEF11 mRNA CTD PMID:16415329 NCBI chr 2:173,074,383...173,195,962
Ensembl chr 2:173,074,368...173,196,010 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATF3 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ATF3 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATP1B1 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATP1B1 mRNA]; Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of ATP1B1 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP		 Ranitidine inhibits the reaction [Rotenone results in increased expression of BAX protein]
Ranitidine inhibits the reaction [Aspirin results in increased expression of BAX protein]		 CTD PMID:19723537 PMID:30885738 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO Ranitidine binds to and results in decreased activity of BCHE protein; Ranitidine inhibits the reaction [Paraoxon results in decreased activity of BCHE protein] CTD PMID:15669026 PMID:16193528 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Ranitidine inhibits the reaction [Rotenone results in decreased expression of BCL2 protein] CTD PMID:19723537 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of BHLHE40 mRNA] CTD PMID:16415329 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of BMP2 mRNA] CTD PMID:16415329 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of BNIP3 mRNA CTD PMID:16401727 PMID:16415329 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of BTG2 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of BTG2 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO Ranitidine results in increased expression of CALCA protein CTD PMID:12495560 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP		 Ranitidine inhibits the reaction [Rotenone results in increased cleavage of and results in increased activity of CASP3 protein]
Ranitidine inhibits the reaction [Aspirin results in increased expression of CASP3 mRNA]; Ranitidine inhibits the reaction [Aspirin results in increased expression of CASP3 protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of CASP3 mRNA]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of CASP3 protein]		 CTD PMID:19723537 PMID:28648817 PMID:29523851 PMID:30580614 PMID:30885738 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Ranitidine inhibits the reaction [Rotenone results in increased cleavage of CASP9 protein] CTD PMID:19723537 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Ranitidine inhibits the reaction [Indomethacin results in increased activity of CAT protein] CTD PMID:16169175 PMID:16397915 PMID:17895592 PMID:18087811 PMID:18726076 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnl1 cyclin L1 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CCNL1 mRNA] CTD PMID:16415329 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein]] CTD PMID:12538815 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of CDK6 mRNA CTD PMID:16415329 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CREM mRNA] CTD PMID:16415329 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA] CTD PMID:16401727 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Ctsl cathepsin L multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CTSL mRNA CTD PMID:16415329 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP Ranitidine results in decreased expression of CXCL1 protein CTD PMID:12023551 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CXCL2 mRNA; [Ranitidine co-treated with Lipopolysaccharides] results in increased expression of CXCL2 protein; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CXCL2 mRNA]; Heparin inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 protein]]; Pentoxifylline inhibits the reaction [[Ranitidine co-treated with Lipopolysaccharides] results in increased expression of CXCL2 protein]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 protein] CTD PMID:16401727 PMID:16415329 PMID:17698507 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in decreased expression of DDAH1 mRNA] CTD PMID:29523851 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of DDIT4 mRNA CTD PMID:16415329 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of DIO3 mRNA] CTD PMID:16415329 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of DUSP1 mRNA CTD PMID:16415329 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Efna1 ephrin A1 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of EFNA1 mRNA] CTD PMID:16415329 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Egfl7 EGF-like-domain, multiple 7 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of EGFL7 mRNA CTD PMID:16415329 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGLN3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGLN3 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766 		JBrowse link
G Egr1 early growth response 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGR1 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of F3 mRNA] CTD PMID:16415329 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fgf23 fibroblast growth factor 23 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FGF23 mRNA CTD PMID:16415329 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 affects metabolic processing ISO FMO3 protein affects the metabolism of Ranitidine CTD PMID:15286053 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FOS mRNA CTD PMID:16415329 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of FOSL2 mRNA] CTD PMID:16415329 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxq1 forkhead box Q1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FOXQ1 mRNA CTD PMID:16415329 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 		JBrowse link
G Fst follistatin multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of FST mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of FST mRNA] CTD PMID:16415329 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GADD45A mRNA CTD PMID:16415329 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gast gastrin affects expression
multiple interactions		 ISO
EXP		 Ranitidine affects the expression of GAST protein
Ranitidine inhibits the reaction [GAST protein modified form results in increased secretion of Acids]		 CTD PMID:2470453 PMID:12503773 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GOT1 mRNA CTD PMID:16415329 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gzmb granzyme B multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GZMB mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GZMB mRNA] CTD PMID:16401727 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G H2ac25 H2A clustered histone 25 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of H2A mRNA CTD PMID:16415329 NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in decreased expression of HMOX1 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of HMOX1 mRNA] CTD PMID:16415329 PMID:30580614 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of HNF4A mRNA CTD PMID:16415329 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of HOMER1 mRNA CTD PMID:16415329 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Hoxa5 homeo box A5 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of HOXA5 mRNA CTD PMID:16415329 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234 		JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions
decreases activity		 ISO
EXP		 [Ranitidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin; Ranitidine binds to and results in decreased activity of HRH2 protein; Ranitidine inhibits the reaction [tiotidine binds to HRH2 protein]
Ranitidine results in decreased activity of HRH2 protein
Ranitidine binds to and results in decreased activity of HRH2 protein; Ranitidine inhibits the reaction [Dimaprit binds to and results in increased activity of HRH2 protein]; Ranitidine inhibits the reaction [Melitten results in increased activity of HRH2 protein]		 CTD PMID:6106871 PMID:6835285 PMID:7512805 PMID:9681472 PMID:9819373 More... NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of HSPA1A mRNA CTD PMID:16415329 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of HSPB8 mRNA] CTD PMID:16415329 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] CTD PMID:11752121 PMID:12538815 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of ID2 mRNA] CTD PMID:16415329 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id4 inhibitor of DNA binding 4 multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of ID4 mRNA] CTD PMID:16415329 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP		 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]]
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IFNG protein]		 CTD PMID:10569698 PMID:11752121 PMID:16415329 PMID:17698507 PMID:19362101 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IFRD1 mRNA CTD PMID:16415329 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Igsf10 immunoglobulin superfamily, member 10 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IGSF10 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IGSF10 mRNA] CTD PMID:16401727 NCBI chr 2:143,575,710...143,605,044
Ensembl chr 2:143,576,070...143,604,773 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP
ISO		 Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]		 CTD PMID:11752121 PMID:17698507 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12A protein] CTD PMID:9819373 PMID:11752121 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12B protein] CTD PMID:9819373 PMID:11752121 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO Ranitidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]] CTD PMID:11752121 PMID:16723495 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine CTD PMID:19362101 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 EXP Pentoxifylline inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of IL1B mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Ranitidine results in increased expression of IL1B protein		 CTD PMID:15265675 PMID:17698507 PMID:30580614 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il4 interleukin 4 multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in increased expression of IL4 protein] CTD PMID:29523851 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IL6 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IL6 mRNA]; Pentoxifylline inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of IL6 protein]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:15265675 PMID:16401727 PMID:16415329 PMID:17698507 PMID:28648817 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhbe inhibin subunit beta E multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of INHBE mRNA CTD PMID:16415329 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of INSIG1 mRNA] CTD PMID:16415329 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of INSIG2 mRNA] CTD PMID:16415329 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of IRS2 mRNA] CTD PMID:16415329 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ITPKC mRNA] CTD PMID:16415329 NCBI chr 1:82,500,957...82,522,533
Ensembl chr 1:82,500,957...82,522,779 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of JUN mRNA] CTD PMID:16415329 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of KLF4 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of KLF4 mRNA] CTD PMID:16401727 PMID:16415329 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klf6 KLF transcription factor 6 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of KLF6 mRNA] CTD PMID:16415329 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Ranitidine inhibits the reaction [Rotenone results in increased phosphorylation of MAPK1 protein] CTD PMID:19723537 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Ranitidine inhibits the reaction [Rotenone results in increased phosphorylation of MAPK3 protein] CTD PMID:19723537 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression
multiple interactions		 EXP Ranitidine results in increased expression of MAPKAPK2 mRNA
[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of MAPKAPK2 mRNA		 CTD PMID:16401727 PMID:16415329 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Ranitidine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of MMP9 protein] CTD PMID:17603938 PMID:29523851 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase decreases expression
multiple interactions		 EXP Ranitidine results in decreased expression of MPO protein
Ranitidine inhibits the reaction [Aspirin results in increased expression of MPO protein]; Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]		 CTD PMID:12023551 PMID:16169175 PMID:17895592 PMID:18726076 PMID:28648817 More... NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of MYC mRNA] CTD PMID:16415329 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NEDD4L mRNA CTD PMID:16415329 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in decreased expression of NFE2L2 mRNA] CTD PMID:28648817 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP Ranitidine inhibits the reaction [Capsaicin results in increased expression of NGF protein] CTD PMID:15265675 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Noct nocturnin multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NOCT mRNA CTD PMID:16415329 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] CTD PMID:16169175 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in decreased expression of NQO1 protein] CTD PMID:30580614 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NR4A1 mRNA CTD PMID:16415329 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NUPR1 mRNA CTD PMID:16415329 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of P4HA1 mRNA CTD PMID:16415329 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Ranitidine inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:19723537 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pfkl phosphofructokinase, liver type multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of PFKL mRNA CTD PMID:16415329 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of PPP1R15A mRNA] CTD PMID:16415329 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Preb prolactin regulatory element binding multiple interactions EXP Ranitidine inhibits the reaction [Lipopolysaccharides results in increased expression of PREB mRNA] CTD PMID:16415329 NCBI chr 6:25,418,805...25,422,594
Ensembl chr 6:25,418,776...25,422,590 		JBrowse link
G Prl prolactin affects expression
increases secretion		 ISO Ranitidine affects the expression of PRL protein
Ranitidine results in increased secretion of PRL protein		 CTD PMID:7878608 PMID:9037573 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of PTGS2 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of PTGS2 mRNA]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:16401727 PMID:16415329 PMID:29523851 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pvr PVR cell adhesion molecule multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of PVR mRNA] CTD PMID:16415329 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of RAC1 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of RAC1 mRNA] CTD PMID:16401727 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Ranitidine inhibits the reaction [Indomethacin results in increased expression of RELA mRNA]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of RELA protein] CTD PMID:28648817 PMID:30580614 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ren renin affects activity ISO Ranitidine affects the activity of REN protein CTD PMID:1972605 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of RGS2 mRNA] CTD PMID:16415329 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of RGS4 mRNA] CTD PMID:16415329 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rhob ras homolog family member B multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ARHB mRNA] CTD PMID:16415329 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SERPINE1 mRNA; Heparin inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]]; Pentoxifylline inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein] CTD PMID:16401727 PMID:16415329 PMID:17698507 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of APS mRNA CTD PMID:16415329 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of SHANK3 mRNA CTD PMID:16415329 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Sik1 salt-inducible kinase 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SIK1 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SIK1 mRNA] CTD PMID:16415329 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Slc16a6 solute carrier family 16, member 6 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC16A6 mRNA CTD PMID:16415329 NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC20A1 mRNA CTD PMID:16415329 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions
affects transport
increases uptake		 ISO
EXP		 Ranitidine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
SLC22A1 protein affects the transport of Ranitidine
SLC22A1 protein results in increased uptake of Ranitidine		 CTD PMID:16006492 PMID:16141367 PMID:16263091 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases uptake
multiple interactions		 ISO
EXP		 SLC22A2 protein results in increased uptake of Ranitidine
Ranitidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]		 CTD PMID:16006492 PMID:16141367 PMID:16263091 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Ranitidine inhibits the reaction [SLC22A3 protein affects the transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Ranitidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16141367 PMID:16263091 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases uptake ISO SLC22A6 protein results in increased uptake of Ranitidine CTD PMID:16006492 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases uptake ISO SLC22A7 protein results in increased uptake of Ranitidine CTD PMID:16006492 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake
multiple interactions		 ISO
EXP		 SLC22A8 protein results in increased uptake of Ranitidine
Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Ranitidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Ranitidine]; Ranitidine inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]		 CTD PMID:15319347 PMID:16006492 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SLC2A1 mRNA] CTD PMID:16415329 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SLC38A2 mRNA] CTD PMID:16415329 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Ranitidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Ranitidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC5A3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC5A3 mRNA] CTD PMID:16401727 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Slk STE20-like kinase multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLK mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLK mRNA] CTD PMID:16401727 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530 		JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SPHK1 mRNA] CTD PMID:16415329 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO Ranitidine results in increased expression of TAC1 protein CTD PMID:12495560 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tfrc transferrin receptor multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TFRC mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TFRC mRNA] CTD PMID:16401727 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]]; Ranitidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Ranitidine; Ranitidine inhibits the reaction [Aspirin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Indomethacin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]		 CTD PMID:11752121 PMID:12023551 PMID:12538815 PMID:15265675 PMID:17698507 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNFAIP6 mRNA] CTD PMID:16415329 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNFRSF12A mRNA] CTD PMID:16415329 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tpm3 tropomyosin 3 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TPM3 mRNA CTD PMID:16415329 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Trak2 trafficking kinesin protein 2 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TRAK2 mRNA CTD PMID:16415329 NCBI chr 9:60,348,531...60,414,036
Ensembl chr 9:60,350,012...60,413,996 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of UBE2B mRNA CTD PMID:16415329 NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of VEGFA mRNA CTD PMID:16415329 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 multiple interactions EXP [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ZBTB10 mRNA CTD PMID:16415329 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515 		JBrowse link
G Zfyve27 zinc finger FYVE-type containing 27 multiple interactions EXP Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ZFYVE27 mRNA] CTD PMID:16415329 NCBI chr 1:240,979,831...241,003,193
Ensembl chr 1:240,979,842...241,003,193 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        xenobiotic 18739
          ranitidine 136
            ranitidine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    main group molecular entity 19789
                      s-block molecular entity 19626
                        hydrogen molecular entity 19613
                          hydrides 19120
                            inorganic hydride 18118
                              pnictogen hydride 18107
                                nitrogen hydride 18014
                                  azane 17824
                                    ammonia 17823
                                      organic amino compound 17823
                                        tertiary amino compound 10142
                                          ranitidine 136
                                            ranitidine hydrochloride 0
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