ONTOLOGY REPORT - ANNOTATIONS
Term: multicellular organismal response to stress
Accession: GO:0033555
browse the term
Definition: Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
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Acp5
acid phosphatase 5, tartrate resistant
IEP
restraint
RGD
PMID:19113077
RGD:2315906
NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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Adam11
ADAM metallopeptidase domain 11
involved_in
ISO
(PMID:26269648)
RGD
PMID:26269648
NCBI chr10:87,724,115...87,742,773
Ensembl chr10:87,724,234...87,741,562
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Adcyap1r1
ADCYAP receptor type I
IEP
RGD
PMID:19181454
RGD:2315958
NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
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Avp
arginine vasopressin
IEP
associated with heroin withdrawal syndrome
RGD
PMID:17443128
RGD:408364980
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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Comt
catechol-O-methyltransferase
acts_upstream_of_or_within
ISO
(PMID:31164811)
RGD
PMID:31164811
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Erbb2
erb-b2 receptor tyrosine kinase 2
IEP
RGD
PMID:27133902
RGD:405650400
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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Erbb4
erb-b2 receptor tyrosine kinase 4
IEP
RGD
PMID:27133902
RGD:405650400
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
IEP
RGD
PMID:26679226
RGD:401940179
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
IEP
RGD
PMID:20309729
RGD:2325868
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Grm7
glutamate metabotropic receptor 7
acts_upstream_of_or_within
ISO
MGI:1857984 (PMID:12814372)
RGD
PMID:12814372
NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344
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Hdac5
histone deacetylase 5
acts_upstream_of_or_within
ISO
MGI:3056065 (PMID:17988634)
RGD
PMID:17988634
NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
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Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
IEP
whole-body immobilization
RGD
PMID:16962226
RGD:2326150
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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Ido1
indoleamine 2,3-dioxygenase 1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3505776 (PMID:19234218)
Ensembl RGD
PMID:19234218
GO_REF:0000107
NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
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Kcne2
potassium voltage-gated channel subfamily E regulatory subunit 2
involved_in
ISO
MGI:3699589 (PMID:24595108)
RGD
PMID:24595108
NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
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Kiaa0319
KIAA0319 homolog
acts_upstream_of_or_within
ISO
MGI:5696928 (PMID:27510895)
RGD
PMID:27510895
NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
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Lrp11
LDL receptor related protein 11
involved_in
ISO
(PMID:25262641)
RGD
PMID:25262641
NCBI chr 1:2,048,307...2,108,115
Ensembl chr 1:2,079,438...2,108,110
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Mecp2
methyl CpG binding protein 2
acts_upstream_of_or_within
ISO
MGI:2183727 (PMID:17108082)
RGD
PMID:17108082
NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689
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Ncam1
neural cell adhesion molecule 1
IDA
RGD
PMID:17429411
RGD:2326013
NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
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Nos1
nitric oxide synthase 1
involved_in
ISO IEA
(PMID:18391107) GO_REF:0000107
RGD Ensembl
PMID:18391107
GO_REF:0000107
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Nrg1
neuregulin 1
IEP
RGD
PMID:27133902
RGD:405650400
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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Ppp3ca
protein phosphatase 3 catalytic subunit alpha
acts_upstream_of_or_within
ISO
(PMID:11782539)
RGD
PMID:11782539
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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Prl
prolactin
IEP
RGD
PMID:17573075
RGD:1642569
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Pten
phosphatase and tensin homolog
involved_in
ISO
(PMID:16675393)
RGD
PMID:16675393
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Selenon
selenoprotein N
acts_upstream_of_or_within
ISO
MGI:5297977 (PMID:21858002)
RGD
PMID:21858002
NCBI chr 5:146,748,638...146,764,656
Ensembl chr 5:146,748,652...146,763,059
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Umod
uromodulin
acts_upstream_of_or_within
ISO
(PMID:19214995)
RGD
PMID:19214995
NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
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Adcyap1
adenylate cyclase activating polypeptide 1
IDA
RGD
PMID:17641738
RGD:2325286
NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
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Als2
alsin Rho guanine nucleotide exchange factor ALS2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3522476 (PMID:16107644)
Ensembl RGD
PMID:16107644
GO_REF:0000107
NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737
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Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
acts_upstream_of_or_within
ISO
MGI:2183465 (PMID:26131556)
RGD
PMID:26131556
NCBI chr10:74,214,143...74,602,825
Ensembl chr10:74,218,915...74,663,295
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Asic1
acid sensing ion channel subunit 1
acts_upstream_of_or_within
ISO
(PMID:25828470)
RGD
PMID:25828470
NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
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Asic4
acid sensing ion channel subunit family member 4
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:25828470)
Ensembl RGD
PMID:25828470
GO_REF:0000107
NCBI chr 9:76,941,532...76,962,900
Ensembl chr 9:76,941,532...76,962,900
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
acts_upstream_of_or_within
ISO
(PMID:12805306)
RGD
PMID:12805306
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
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Bcl2
BCL2, apoptosis regulator
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857430 (PMID:16095731)
Ensembl RGD
PMID:16095731
GO_REF:0000107
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bdnf
brain-derived neurotrophic factor
acts_upstream_of_or_within
ISO
MGI:2176750 (PMID:15249684)
RGD
PMID:15249684
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Brinp1
BMP/retinoic acid inducible neural specific 1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:5698819 (PMID:24528488)
Ensembl RGD
PMID:24528488
GO_REF:0000107
NCBI chr 5:82,348,501...82,550,506
Ensembl chr 5:82,348,930...82,493,150
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Cacna1e
calcium voltage-gated channel subunit alpha1 E
acts_upstream_of_or_within
ISO
MGI:2451031 (PMID:11854466)
RGD
PMID:11854466
NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
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Comt
catechol-O-methyltransferase
acts_upstream_of_or_within
ISO
(PMID:31164811)
RGD
PMID:31164811
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Dbi
diazepam binding inhibitor
acts_upstream_of_or_within
ISO
(PMID:17150371)
RGD
PMID:17150371
NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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Deaf1
DEAF1 transcription factor
involved_in
ISO
(PMID:24726472)
RGD
PMID:24726472
NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
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Dpp4
dipeptidylpeptidase 4
acts_upstream_of_or_within
ISO
MGI:2150161 (PMID:16712972)
RGD
PMID:16712972
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Drd1
dopamine receptor D1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857158 (PMID:11172752)
Ensembl RGD
PMID:11172752
GO_REF:0000107
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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Drd4
dopamine receptor D4
IMP
RGD
PMID:16708027
RGD:1600974
NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
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Eif4e
eukaryotic translation initiation factor 4E
acts_upstream_of_or_within involved_in
ISO IEA
MGI:1270849|MGI:2384784 (PMID:24990923) GO_REF:0000107
RGD Ensembl
PMID:24990923
GO_REF:0000107
NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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Eif4g1
eukaryotic translation initiation factor 4 gamma 1
acts_upstream_of_or_within
ISO
MGI:1270849|MGI:95305 (PMID:24990923)
RGD
PMID:24990923
NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
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Esr2
estrogen receptor 2
IDA
RGD
PMID:15514081
RGD:1582265
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Fbxl20
F-box and leucine-rich repeat protein 20
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3765911 (PMID:21390313)
Ensembl RGD
PMID:21390313
GO_REF:0000107
NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162
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Gabra5
gamma-aminobutyric acid type A receptor subunit alpha 5
acts_upstream_of_or_within
ISO
MGI:2183170 (PMID:12084936)
RGD
PMID:12084936
NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
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Gng7
G protein subunit gamma 7
acts_upstream_of_or_within
ISO
MGI:2451322 (PMID:12488442)
RGD
PMID:12488442
NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
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Grik2
glutamate ionotropic receptor kainate type subunit 2
acts_upstream_of_or_within
ISO
MGI:1857979 (PMID:15673679)
RGD
PMID:15673679
NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
acts_upstream_of_or_within
IMP ISO
MGI:3701351 (PMID:16710293)
RGD
PMID:16710293 PMID:21285873
RGD:13210750
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Grm7
glutamate metabotropic receptor 7
NOT|involved_in acts_upstream_of_or_within
ISO
(PMID:17167337) MGI:1857984 (PMID:9920659)
RGD
PMID:9920659 PMID:17167337
NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344
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Hcrt
hypocretin neuropeptide precursor
NAS
RGD
PMID:14614918
RGD:1358373
NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
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Htr1a
5-hydroxytryptamine receptor 1A
involved_in
ISS ISO
GO_REF:0000024 (PMID:9826725)
UniProt RGD
PMID:9826725
GO_REF:0000024
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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Htr2c
5-hydroxytryptamine receptor 2C
involved_in
ISS ISO
GO_REF:0000024 (PMID:17451451)
UniProt RGD
PMID:17451451
GO_REF:0000024
NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287
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Large1
LARGE xylosyl- and glucuronyltransferase 1
acts_upstream_of_or_within
ISO
(PMID:29915039)
RGD
PMID:29915039
NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
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Lypd1
Ly6/Plaur domain containing 1
acts_upstream_of_or_within
ISO
MGI:3840549 (PMID:19246390)
RGD
PMID:19246390
NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493
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Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
involved_in
ISO
(PMID:21048139)
RGD
PMID:21048139
NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
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Mdk
midkine
involved_in
IEA ISO
GO_REF:0000107 (PMID:10096022)
Ensembl RGD
PMID:10096022
GO_REF:0000107
NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
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Mecp2
methyl CpG binding protein 2
acts_upstream_of_or_within
ISO
MGI:2158353|MGI:2176754|MGI:3800596 (PMID:16199017), (PMID:16467389)
RGD
PMID:16199017 PMID:16467389
NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689
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Morc1
MORC family CW-type zinc finger 1
acts_upstream_of_or_within
ISO
MGI:1857787 (PMID:26275923)
RGD
PMID:26275923
NCBI chr11:52,178,769...52,384,255
Ensembl chr11:52,178,769...52,384,255
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Neurod2
neuronal differentiation 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2385828 (PMID:16203979)
Ensembl RGD
PMID:16203979
GO_REF:0000107
NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986
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Npy2r
neuropeptide Y receptor Y2
IMP
RGD
PMID:11830176
RGD:633496
NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
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Nr2e1
nuclear receptor subfamily 2, group E, member 1
acts_upstream_of_or_within
ISO
MGI:2151350 (PMID:12527005)
RGD
PMID:12527005
NCBI chr20:46,050,134...46,071,257
Ensembl chr20:46,050,414...46,073,949
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Pde8b
phosphodiesterase 8B
acts_upstream_of_or_within
ISO
(PMID:22925203)
RGD
PMID:22925203
NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209
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Penk
proenkephalin
acts_upstream_of_or_within
ISO
MGI:2388020 (PMID:11172058)
RGD
PMID:11172058
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
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Rps6kb1
ribosomal protein S6 kinase B1
acts_upstream_of_or_within
ISO
MGI:2384784|MGI:95305 (PMID:24990923)
RGD
PMID:24990923
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Slc1a1
solute carrier family 1 member 1
acts_upstream_of_or_within
ISO
MGI:2655190 (PMID:22221107), (PMID:22732503)
RGD
PMID:22221107 PMID:22732503
NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
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Spire1
spire-type actin nucleation factor 1
acts_upstream_of_or_within
ISO
MGI:4310183 (PMID:24345451)
RGD
PMID:24345451
NCBI chr18:61,041,914...61,171,670
Ensembl chr18:61,041,290...61,171,899
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Taar4
trace amine-associated receptor 4
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:21,481,050...21,482,093
Ensembl chr 1:21,481,050...21,482,093
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Usp46
ubiquitin specific peptidase 46
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:5438668 (PMID:22720038)
Ensembl RGD
PMID:22720038
GO_REF:0000107
NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
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Vdac1
voltage-dependent anion channel 1
acts_upstream_of_or_within
ISO
MGI:2182154 (PMID:11907043)
RGD
PMID:11907043
NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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Vdac3
voltage-dependent anion channel 3
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2182182 (PMID:11907043)
Ensembl RGD
PMID:11907043
GO_REF:0000107
NCBI chr16:69,434,982...69,451,473
Ensembl chr16:69,435,005...69,451,471
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Adam11
ADAM metallopeptidase domain 11
involved_in
ISO
(PMID:16729981)
RGD
PMID:16729981
NCBI chr10:87,724,115...87,742,773
Ensembl chr10:87,724,234...87,741,562
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Scn11a
sodium voltage-gated channel alpha subunit 11
involved_in
IEA ISO
GO_REF:0000107 MGI:3528983 (PMID:19931571)
Ensembl RGD
PMID:19931571
GO_REF:0000107
NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044
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Adam11
ADAM metallopeptidase domain 11
involved_in
ISO
(PMID:16729981)
RGD
PMID:16729981
NCBI chr10:87,724,115...87,742,773
Ensembl chr10:87,724,234...87,741,562
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Ntrk1
neurotrophic receptor tyrosine kinase 1
acts_upstream_of_or_within
ISO
(PMID:24760869)
RGD
PMID:24760869
NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
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P2rx3
purinergic receptor P2X 3
IMP
RGD
PMID:24120766
RGD:10043614
NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
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Scn11a
sodium voltage-gated channel alpha subunit 11
involved_in
IEA ISO
GO_REF:0000107 MGI:3528983 (PMID:19931571)
Ensembl RGD
PMID:19931571
GO_REF:0000107
NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044
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Scn9a
sodium voltage-gated channel alpha subunit 9
IMP
RGD
PMID:31550995
RGD:150429745
NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516
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Akt1
AKT serine/threonine kinase 1
involved_in
IEA ISO
GO_REF:0000107 MGI:1914047|MGI:1928394 (PMID:31874168)
Ensembl RGD
PMID:31874168
GO_REF:0000107
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Cacna1a
calcium voltage-gated channel subunit alpha1 A
acts_upstream_of_or_within
ISO
MGI:2180190 (PMID:16890369)
RGD
PMID:16890369
NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
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Cacna1e
calcium voltage-gated channel subunit alpha1 E
acts_upstream_of_or_within
ISO
MGI:2179732 (PMID:10801976)
RGD
PMID:10801976
NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
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Capn2
calpain 2
IDA
RGD
PMID:25150005
RGD:13792585
NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
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Cntnap2
contactin associated protein 2
involved_in
ISO
MGI:1928394|MGI:87986 (PMID:31874168)
RGD
PMID:31874168
NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
G
Crhr1
corticotropin releasing hormone receptor 1
IMP
RGD
PMID:17550594
RGD:1626231
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
G
Git2
GIT ArfGAP 2
acts_upstream_of_or_within
ISO
MGI:3762635 (PMID:23870131)
RGD
PMID:23870131
NCBI chr12:41,829,717...41,872,621
Ensembl chr12:41,829,730...41,871,097
G
Gria1
glutamate ionotropic receptor AMPA type subunit 1
IEP
RGD
PMID:25716866
RGD:401976466
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
G
Grik1
glutamate ionotropic receptor kainate type subunit 1
acts_upstream_of_or_within
ISO
MGI:2176347 (PMID:15673679)
RGD
PMID:15673679
NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
acts_upstream_of_or_within
ISO
MGI:1928295 (PMID:11711849)
RGD
PMID:11711849
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Htr7
5-hydroxytryptamine receptor 7
IMP
RGD
PMID:16098671
RGD:6480679
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
G
Kcnip3
potassium voltage-gated channel interacting protein 3
acts_upstream_of_or_within
ISO
MGI:2679303 (PMID:14534243)
RGD
PMID:14534243
NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
G
Lpar5
lysophosphatidic acid receptor 5
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 MGI:5431493 (PMID:22461625)
GO_Central RGD
PMID:22461625
GO_REF:0000033
NCBI chr 4:157,870,493...157,883,979
Ensembl chr 4:157,881,796...157,882,950
G
Mtor
mechanistic target of rapamycin kinase
involved_in
IEA ISO
GO_REF:0000107 MGI:1914047|MGI:87986 (PMID:31874168)
Ensembl RGD
PMID:31874168
GO_REF:0000107
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Osm
oncostatin M
acts_upstream_of_or_within
ISO
MGI:3574987 (PMID:14985435)
RGD
PMID:14985435
NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
G
P2rx2
purinergic receptor P2X 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1097160|MGI:2687349 (PMID:15961431)
Ensembl RGD
PMID:15961431
GO_REF:0000107
NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
G
P2rx3
purinergic receptor P2X 3
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1934019|MGI:2385840|MGI:2665170 (PMID:11069181), (PMID:11069182), (PMID:15961431)
Ensembl RGD
PMID:11069181 PMID:11069182 PMID:15961431
GO_REF:0000107
NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
G
P2rx4
purinergic receptor P2X 4
involved_in
IMP
PMID:12917686
ARUK-UCL
PMID:12917686
RGD:13673840
NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
treatment
IDA
RGD
PMID:25919859
RGD:152025537
NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
G
Pirt
phosphoinositide-interacting regulator of transient receptor potential channels
acts_upstream_of_or_within
ISO
MGI:3834636 (PMID:18455988)
RGD
PMID:18455988
NCBI chr10:51,613,202...51,628,108
Ensembl chr10:51,613,126...51,632,264
G
Runx1
RUNX family transcription factor 1
acts_upstream_of_or_within
ISO
(PMID:16446141)
RGD
PMID:16446141
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
G
Scn10a
sodium voltage-gated channel alpha subunit 10
involved_in
ISO
MGI:2180183 (PMID:24440715)
RGD
PMID:24440715
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
G
Scn11a
sodium voltage-gated channel alpha subunit 11
involved_in
ISO
MGI:3528983 (PMID:19931571)
RGD
PMID:19931571
NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044
G
Scn3a
sodium voltage-gated channel alpha subunit 3
involved_in
IEA ISO
GO_REF:0000107 MGI:5505523 (PMID:24440715)
Ensembl RGD
PMID:24440715
GO_REF:0000107
NCBI chr 3:50,146,411...50,258,119
Ensembl chr 3:50,148,139...50,258,119
G
Scn9a
sodium voltage-gated channel alpha subunit 9
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3053097 (PMID:24440715) MGI:3053098 (PMID:15314237)
Ensembl RGD
PMID:15314237 PMID:24440715
GO_REF:0000107
NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516
G
Tacr1
tachykinin receptor 1
IMP
RGD
PMID:18407414
RGD:2304276
NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
G
Thbs1
thrombospondin 1
involved_in
ISO
(PMID:22745497)
RGD
PMID:22745497
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
G
Thbs4
thrombospondin 4
involved_in
IMP ISO IEA
PMID:22745497 (PMID:22745497) GO_REF:0000107
RGD Ensembl
PMID:22745497 PMID:22745497
GO_REF:0000107, RGD:8553360
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
acts_upstream_of_or_within
ISO
MGI:1934023 (PMID:17767493), (PMID:18272658), (PMID:18455988)
RGD
PMID:17767493 PMID:18272658 PMID:18455988
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
G
Tspo
translocator protein
IMP
RGD
PMID:19555675
RGD:2317138
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
G
Vwa1
von Willebrand factor A domain containing 1
acts_upstream_of_or_within
ISO
MGI:3809230 (PMID:19279005)
RGD
PMID:19279005
NCBI chr 5:166,377,451...166,382,784
Ensembl chr 5:166,377,455...166,382,637
G
Adra2a
adrenoceptor alpha 2A
acts_upstream_of_or_within
ISO
(PMID:15105370)
RGD
PMID:15105370
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
G
Adrb1
adrenoceptor beta 1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:15066288)
Ensembl RGD
PMID:15066288
GO_REF:0000107
NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
G
Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
acts_upstream_of_or_within
ISO
MGI:6729893 (PMID:21731499)
RGD
PMID:21731499
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
G
Atp1a3
ATPase Na+/K+ transporting subunit alpha 3
acts_upstream_of_or_within
ISO
MGI:4356167 (PMID:26463346), (PMID:26501181)
RGD
PMID:26463346 PMID:26501181
NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
G
Bdnf
brain-derived neurotrophic factor
acts_upstream_of_or_within
ISO
MGI:2176750 (PMID:15249684)
RGD
PMID:15249684
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
G
Cacna1e
calcium voltage-gated channel subunit alpha1 E
acts_upstream_of_or_within
ISO
MGI:2179732 (PMID:10801976)
RGD
PMID:10801976
NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
G
Comt
catechol-O-methyltransferase
acts_upstream_of_or_within
ISO
MGI:2178542 (PMID:22192380), (PMID:24509724)
RGD
PMID:22192380 PMID:24509724
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
G
Crhr1
corticotropin releasing hormone receptor 1
involved_in
IEA ISO
GO_REF:0000107 (PMID:9655498)
Ensembl RGD
PMID:9655498
GO_REF:0000107
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
G
Dbh
dopamine beta-hydroxylase
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857556 (PMID:15066288)
Ensembl RGD
PMID:15066288
GO_REF:0000107
NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
G
Drd4
dopamine receptor D4
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2178631 (PMID:11860516)
Ensembl RGD
PMID:11860516
GO_REF:0000107
NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
G
Ext1
exostosin glycosyltransferase 1
acts_upstream_of_or_within
ISO
(PMID:22411800)
RGD
PMID:22411800
NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
acts_upstream_of_or_within
ISO
(PMID:16157280)
RGD
PMID:16157280
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Nr4a2
nuclear receptor subfamily 4, group A, member 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2429971 (PMID:12385813)
Ensembl RGD
PMID:12385813
GO_REF:0000107
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
G
Crhr1
corticotropin releasing hormone receptor 1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2178543 (PMID:11988580)
Ensembl RGD
PMID:11988580
GO_REF:0000107
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
G
Hcn1
hyperpolarization-activated cyclic nucleotide-gated potassium channel 1
acts_upstream_of_or_within
ISO
(PMID:30886335)
RGD
PMID:30886335
NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774
G
Penk
proenkephalin
IEP
RGD
PMID:23665402
RGD:10003151
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
G
Tmem74
transmembrane protein 74
acts_upstream_of_or_within
ISO
MGI:6690870 (PMID:30886335)
RGD
PMID:30886335
NCBI chr 7:74,929,290...74,937,929
Ensembl chr 7:74,931,694...74,937,934
G
Zfp212
Zinc finger protein 212
acts_upstream_of_or_within
ISO
MGI:6830528 (PMID:34815492)
RGD
PMID:34815492
NCBI chr 4:76,923,638...76,936,076
Ensembl chr 4:76,923,668...76,936,066
G
Cck
cholecystokinin
IMP
RGD
PMID:12450740
RGD:1626100
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
IMP
RGD
PMID:31329100
RGD:407571699
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Cck
cholecystokinin
IDA
RGD
PMID:12373548
RGD:1358453
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
G
Cckbr
cholecystokinin B receptor
IMP
RGD
PMID:12373548
RGD:1358453
NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
G
Crh
corticotropin releasing hormone
IDA
RGD
PMID:10366634
RGD:5508167
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Gja1
gap junction protein, alpha 1
IMP
RGD
PMID:22665389
RGD:7207267
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Grp
gastrin releasing peptide
involved_in
ISS ISO
GO_REF:0000024 (PMID:34610277)
UniProt RGD
PMID:34610277
GO_REF:0000024
NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
G
Grpr
gastrin releasing peptide receptor
involved_in
ISS ISO
GO_REF:0000024 (PMID:34610277)
UniProt RGD
PMID:34610277
GO_REF:0000024
NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
G
Mef2c
myocyte enhancer factor 2C
involved_in
ISS ISO
GO_REF:0000024 (PMID:18579729)
UniProt RGD
PMID:18579729
GO_REF:0000024
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
G
Npas2
neuronal PAS domain protein 2
involved_in
ISO
(PMID:29163035)
RGD
PMID:29163035
NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
G
Penk
proenkephalin
IMP
RGD
PMID:23368426
RGD:10040949
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
G
Ucn
urocortin
IDA
RGD
PMID:10366634
RGD:5508167
NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
G
Prkar1b
protein kinase cAMP-dependent type I regulatory subunit beta
IMP
RGD
PMID:33479380
RGD:150519900
NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942
G
Apoe
apolipoprotein E
involved_in
ISO IEA
(PMID:24412220) GO_REF:0000107
RGD Ensembl
PMID:24412220
GO_REF:0000107
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Ephb2
Eph receptor B2
IMP
RGD
PMID:26354908
RGD:127285622
NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
G
Rag1
recombination activating 1
IMP
RGD
PMID:22964459
RGD:12907572
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
G
Shank3
SH3 and multiple ankyrin repeat domains 3
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:21423165) GO_REF:0000107
BHF-UCL RGD Ensembl
PMID:21423165
GO_REF:0000024 GO_REF:0000107
NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
G
Aqp9
aquaporin 9
IMP
RGD
PMID:31746418
RGD:152995474
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
G
Atat1
alpha tubulin acetyltransferase 1
involved_in
IEA ISO
GO_REF:0000107 MGI:5549959 (PMID:27976998)
Ensembl RGD
PMID:27976998
GO_REF:0000107
NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964
G
Cacna1a
calcium voltage-gated channel subunit alpha1 A
acts_upstream_of_or_within
ISO
MGI:1856210 (PMID:11718712)
RGD
PMID:11718712
NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
G
Cacna1b
calcium voltage-gated channel subunit alpha1 B
acts_upstream_of_or_within
ISO
(PMID:12074836)
RGD
PMID:12074836
NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
G
Cacna1e
calcium voltage-gated channel subunit alpha1 E
acts_upstream_of_or_within
ISO
(PMID:12074836)
RGD
PMID:12074836
NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
G
Calca
calcitonin-related polypeptide alpha
acts_upstream_of_or_within
ISO
MGI:2148771 (PMID:10208559)
RGD
PMID:10208559
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
G
Cntnap2
contactin associated protein 2
involved_in
ISO
MGI:2677631 (PMID:29429934)
RGD
PMID:29429934
NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
G
Col6a1
collagen type VI alpha 1 chain
acts_upstream_of_or_within
ISO
MGI:2153356 (PMID:24277578)
RGD
PMID:24277578
NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
G
Comt
catechol-O-methyltransferase
IMP
RGD
PMID:17084978
RGD:2289747
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
G
Crh
corticotropin releasing hormone
IEP
RGD
PMID:21463663
RGD:5490545
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Dbh
dopamine beta-hydroxylase
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857556 (PMID:11805341)
Ensembl RGD
PMID:11805341
GO_REF:0000107
NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
G
Ednrb
endothelin receptor type B
IMP
RGD
PMID:12847519
RGD:1581889
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
G
Gch1
GTP cyclohydrolase 1
involved_in
IDA
PMID:17057711
UniProt
PMID:17057711
RGD:8554553
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
G
Gja4
gap junction protein, alpha 4
IEP
RGD
PMID:11978404
RGD:728686
NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
G
Kcnip3
potassium voltage-gated channel interacting protein 3
acts_upstream_of_or_within
ISO
MGI:2179103 (PMID:11792319)
RGD
PMID:11792319
NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
G
Mir154
microRNA 154
IEP
RGD
PMID:31746418
RGD:152995474
NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
G
Nmur2
neuromedin U receptor 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3701426 (PMID:17030627)
Ensembl RGD
PMID:17030627
GO_REF:0000107
NCBI chr10:40,166,223...40,182,078
Ensembl chr10:40,166,226...40,182,078
G
Prkcg
protein kinase C, gamma
involved_in
ISS ISO
GO_REF:0000024 (PMID:9323205)
UniProt RGD
PMID:9323205
GO_REF:0000024
NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
G
Reln
reelin
involved_in acts_upstream_of_or_within
ISS ISO IEA
GO_REF:0000024 MGI:1856398 (PMID:16580148) GO_REF:0000107
UniProt RGD Ensembl
PMID:16580148
GO_REF:0000024 GO_REF:0000107
NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
G
Ret
ret proto-oncogene
involved_in
ISO
(PMID:20237269)
RGD
PMID:20237269
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
G
Scn11a
sodium voltage-gated channel alpha subunit 11
involved_in
ISO
MGI:3604572|MGI:6392908|MGI:6415024|MGI:6415027 (PMID:17167076), (PMID:17363266), (PMID:27224030), (PMID:30557356)
RGD
PMID:17167076 PMID:17363266 PMID:27224030 PMID:30557356
NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044
G
Slc6a2
solute carrier family 6 member 2
acts_upstream_of_or_within
ISO
(PMID:11805341)
RGD
PMID:11805341
NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
G
Tac1
tachykinin, precursor 1
acts_upstream_of_or_within
ISO
(PMID:11805341)
RGD
PMID:11805341
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
G
Tacr1
tachykinin receptor 1
acts_upstream_of_or_within
ISO
(PMID:11805341)
RGD
PMID:11805341
NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
G
Trpa1
transient receptor potential cation channel, subfamily A, member 1
acts_upstream_of_or_within
ISO
MGI:3624810 (PMID:16630838), (PMID:18272293), (PMID:18297068)
RGD
PMID:16630838 PMID:18272293 PMID:18297068
NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
acts_upstream_of_or_within
ISO
MGI:1934023 (PMID:18272293), (PMID:18297068)
RGD
PMID:18272293 PMID:18297068
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
G
Tspo
translocator protein
IEP
RGD
PMID:19555675
RGD:2317138
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
G
Ucn
urocortin
IEP
RGD
PMID:21463663
RGD:5490545
NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all