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Gene: Scn11a (sodium voltage-gated channel alpha subunit 11) Rattus norvegicus
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Symbol: Scn11a
Name: sodium voltage-gated channel alpha subunit 11
RGD ID: 3630
Description: Predicted to have voltage-gated sodium channel activity. Predicted to be involved in several processes, including membrane depolarization during action potential; neuronal action potential; and regulation of sensory perception of pain. Localizes to axon; glutamatergic synapse; and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 3 and hereditary sensory and autonomic neuropathy type 7. Orthologous to human SCN11A (sodium voltage-gated channel alpha subunit 11); INTERACTS WITH 6-propyl-2-thiouracil; amitriptyline; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: NaN; sensory neuron sodium channel 2; sodium channel protein type 11 subunit alpha; sodium channel protein type XI subunit alpha; sodium channel voltage-gated type 11 alpha polypeptide; sodium channel voltage-gated type XI alpha polypeptide; sodium channel, voltage-gated, type 11, alpha polypeptide; sodium channel, voltage-gated, type XI, alpha; sodium channel, voltage-gated, type XI, alpha polypeptide; sodium channel, voltage-gated, type XI, alpha subunit; sodium channel, voltage-gated, type11, alpha polypeptide; voltage-gated sodium channel NAV1.9b; voltage-gated sodium channel subunit alpha Nav1.9
Orthologs:
Homo sapiens (human) : SCN11A (sodium voltage-gated channel alpha subunit 11)  HGNC  Alliance
Mus musculus (house mouse) : Scn11a (sodium channel, voltage-gated, type XI, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn11a (sodium voltage-gated channel alpha subunit 11)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Canis lupus familiaris (dog) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn11a (sodium voltage-gated channel alpha subunit 11)
Sus scrofa (pig) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Chlorocebus sabaeus (African green monkey) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Heterocephalus glaber (naked mole-rat) : Scn11a (sodium voltage-gated channel alpha subunit 11)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08128,450,793 - 128,527,510 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,450,801 - 128,521,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,654,010 - 127,724,293 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,724,493 - 124,794,654 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,744,232 - 124,814,391 (-)NCBI
Celera8118,645,022 - 118,713,950 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scn11a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3630
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.