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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-bromocarboxylic acid
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Accession:CHEBI:134367 term browser browse the term
Definition:Any carboxylic acid in which the carbon bearing the carboxy group is substituted by a bromine.
Synonyms:related_synonym: 2-bromocarboxylic acids;   Formula=C2H2BrO2R;   SMILES=OC(C(Br)*)=O;   alpha-bromocarboxylic acid;   alpha-bromocarboxylic acids


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2-bromohexadecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 decreases expression EXP 2-bromopalmitate results in decreased expression of APOA1 mRNA CTD PMID:7556148 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA] CTD PMID:30076181 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 2-bromopalmitate results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases activity EXP 2-bromopalmitate results in increased activity of GAPDH protein CTD PMID:10650946 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA] CTD PMID:30076181 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA] CTD PMID:30076181 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 decreases expression ISO 2-bromopalmitate results in decreased expression of LAT2 protein CTD PMID:23001822 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP 2-bromopalmitate results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA] CTD PMID:30076181 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA] CTD PMID:30076181 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases activity
multiple interactions		 ISO 2-bromopalmitate results in increased activity of PPARD protein
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]		 CTD PMID:15997096 PMID:21543282 PMID:23150725 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP 2-bromopalmitate results in increased expression of PPARG protein CTD PMID:10650946 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein CTD PMID:30076181 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA] CTD PMID:30076181 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rbp1 retinol binding protein 1 increases expression EXP 2-bromopalmitate results in increased expression of RBP1 mRNA CTD PMID:12576510 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein] CTD PMID:15997096 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Spi1 Spi-1 proto-oncogene multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA] CTD PMID:30076181 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA] CTD PMID:30076181 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP 2-bromopalmitate results in increased expression of UCP2 mRNA CTD PMID:11341955 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
bromochloroacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta increases expression ISO bromochloroacetic acid results in increased expression of ACTB protein CTD PMID:21296659 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP bromochloroacetic acid results in decreased expression of ACTG2 mRNA CTD PMID:16460773 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP bromochloroacetic acid results in decreased expression of ACTN1 mRNA CTD PMID:16460773 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP bromochloroacetic acid results in decreased expression of ACTN4 mRNA CTD PMID:16460773 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Afp alpha-fetoprotein decreases expression ISO bromochloroacetic acid results in decreased expression of AFP protein CTD PMID:21296659 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression EXP bromochloroacetic acid results in increased expression of AKT2 mRNA CTD PMID:16460773 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression EXP bromochloroacetic acid results in decreased expression of ARF4 mRNA CTD PMID:16460773 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP bromochloroacetic acid results in increased expression of BNIP3L mRNA CTD PMID:16460773 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression EXP bromochloroacetic acid results in decreased expression of CCN3 mRNA CTD PMID:16460773 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Cd34 CD34 molecule decreases expression ISO bromochloroacetic acid results in decreased expression of CD34 protein CTD PMID:21296659 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP bromochloroacetic acid results in decreased expression of CDKN1A mRNA CTD PMID:16460773 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdx2 caudal type homeo box 2 increases expression ISO bromochloroacetic acid results in increased expression of CDX2 protein CTD PMID:21296659 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO bromochloroacetic acid results in decreased expression of COL1A1 protein CTD PMID:21296659 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP bromochloroacetic acid results in decreased expression of COL1A2 mRNA CTD PMID:16460773 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO bromochloroacetic acid results in decreased expression of COL2A1 protein CTD PMID:21296659 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO bromochloroacetic acid results in increased expression of CRABP2 protein CTD PMID:21296659 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Cripto cripto, EGF-CFC family member increases expression ISO bromochloroacetic acid results in increased expression of CRIPTO protein CTD PMID:21296659 NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308 		JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO bromochloroacetic acid results in decreased expression of DDX4 protein CTD PMID:21296659 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO bromochloroacetic acid results in decreased expression of DNMT3B protein CTD PMID:21296659 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO bromochloroacetic acid results in increased expression of EEF1A1 protein CTD PMID:21296659 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Eomes eomesodermin decreases expression ISO bromochloroacetic acid results in decreased expression of EOMES protein CTD PMID:21296659 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Eras ES cell expressed Ras increases expression ISO bromochloroacetic acid results in increased expression of ERAS protein CTD PMID:21296659 NCBI chr  X:14,573,987...14,578,455
Ensembl chr  X:14,573,987...14,578,374 		JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP bromochloroacetic acid results in decreased expression of FAS mRNA CTD PMID:16460773 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fat1 FAT atypical cadherin 1 decreases expression EXP bromochloroacetic acid results in decreased expression of FAT1 mRNA CTD PMID:16460773 NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107 		JBrowse link
G Fgf4 fibroblast growth factor 4 increases expression ISO bromochloroacetic acid results in increased expression of FGF4 protein CTD PMID:21296659 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466 		JBrowse link
G Fgf5 fibroblast growth factor 5 increases expression ISO bromochloroacetic acid results in increased expression of FGF5 protein CTD PMID:21296659 NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO bromochloroacetic acid results in decreased expression of FLT1 protein CTD PMID:21296659 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO bromochloroacetic acid results in increased expression of FN1 protein CTD PMID:21296659 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP bromochloroacetic acid results in decreased expression of FOS mRNA CTD PMID:16460773 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit decreases expression EXP bromochloroacetic acid results in decreased expression of FOSL1 mRNA CTD PMID:16460773 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxa2 forkhead box A2 affects expression ISO bromochloroacetic acid affects the expression of FOXA2 protein CTD PMID:21296659 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression EXP bromochloroacetic acid results in decreased expression of FZD2 mRNA CTD PMID:16460773 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 affects expression ISO bromochloroacetic acid affects the expression of GABRB3 protein CTD PMID:21296659 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression EXP bromochloroacetic acid results in decreased expression of GADD45A mRNA CTD PMID:16460773 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO bromochloroacetic acid results in increased expression of GAL protein CTD PMID:21296659 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO bromochloroacetic acid results in increased expression of GAPDH protein CTD PMID:21296659 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO bromochloroacetic acid results in increased expression of GATA6 protein CTD PMID:21296659 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gbx2 gastrulation brain homeobox 2 increases expression ISO bromochloroacetic acid results in increased expression of GBX2 protein CTD PMID:21296659 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212 		JBrowse link
G Gcm1 glial cells missing transcription factor 1 increases expression ISO bromochloroacetic acid results in increased expression of GCM1 protein CTD PMID:21296659 NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924 		JBrowse link
G Gdf3 growth differentiation factor 3 increases expression ISO bromochloroacetic acid results in increased expression of GDF3 protein CTD PMID:21296659 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO bromochloroacetic acid results in decreased expression of GFAP protein CTD PMID:21296659 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gnaq G protein subunit alpha q decreases expression EXP bromochloroacetic acid results in decreased expression of GNAQ mRNA CTD PMID:16460773 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Grb7 growth factor receptor bound protein 7 increases expression ISO bromochloroacetic acid results in increased expression of GRB7 protein CTD PMID:21296659 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects expression EXP bromochloroacetic acid affects the expression of GSK3B mRNA CTD PMID:16460773 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain affects expression ISO bromochloroacetic acid affects the expression of HBB-B2 protein CTD PMID:21296659 NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbz hemoglobin subunit zeta increases expression ISO bromochloroacetic acid results in increased expression of HBZ protein CTD PMID:21296659 NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312 		JBrowse link
G Iapp islet amyloid polypeptide decreases expression ISO bromochloroacetic acid results in decreased expression of IAPP protein CTD PMID:21296659 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 increases expression ISO bromochloroacetic acid results in increased expression of IFITM1 protein CTD PMID:21296659 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO bromochloroacetic acid results in decreased expression of IFITM2 protein CTD PMID:21296659 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP bromochloroacetic acid results in increased expression of IGF1 mRNA CTD PMID:16460773 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP
ISO		 bromochloroacetic acid results in increased expression of IGFBP2 mRNA
bromochloroacetic acid results in increased expression of IGFBP2 protein		 CTD PMID:16460773 PMID:21296659 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression EXP bromochloroacetic acid results in increased expression of IGFBP3 mRNA CTD PMID:16460773 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression EXP bromochloroacetic acid results in increased expression of IGFBP6 mRNA CTD PMID:16460773 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer increases expression ISO bromochloroacetic acid results in increased expression of IL6ST protein CTD PMID:21296659 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Ilk integrin-linked kinase decreases expression EXP bromochloroacetic acid results in decreased expression of ILK mRNA CTD PMID:16460773 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Ins2 insulin 2 decreases expression ISO bromochloroacetic acid results in decreased expression of INS2 protein CTD PMID:21296659 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itga8 integrin subunit alpha 8 decreases expression EXP bromochloroacetic acid results in decreased expression of ITGA8 mRNA CTD PMID:16460773 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression EXP bromochloroacetic acid results in decreased expression of ITGB1 mRNA CTD PMID:16460773 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb2 integrin subunit beta 2 increases expression EXP bromochloroacetic acid results in increased expression of ITGB2 mRNA CTD PMID:16460773 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO bromochloroacetic acid results in decreased expression of KIT protein CTD PMID:21296659 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Krt1 keratin 1 decreases expression ISO bromochloroacetic acid results in decreased expression of KRT1 protein CTD PMID:21296659 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844 		JBrowse link
G Lama1 laminin subunit alpha 1 increases expression ISO bromochloroacetic acid results in increased expression of LAMA1 protein CTD PMID:21296659 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478 		JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO bromochloroacetic acid results in decreased expression of LAMB1 protein CTD PMID:21296659 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585 		JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression ISO bromochloroacetic acid results in increased expression of LAMC1 protein CTD PMID:21296659 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492 		JBrowse link
G Lefty1 left right determination factor 1 affects expression ISO bromochloroacetic acid affects the expression of LEFTY1 protein CTD PMID:21296659 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720 		JBrowse link
G Lifr LIF receptor subunit alpha increases expression ISO bromochloroacetic acid results in increased expression of LIFR protein CTD PMID:21296659 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
G Lin28a lin-28 homolog A decreases expression ISO bromochloroacetic acid results in decreased expression of LIN28A protein CTD PMID:21296659 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression EXP bromochloroacetic acid results in increased expression of MAPKAPK2 mRNA CTD PMID:16460773 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 decreases expression ISO bromochloroacetic acid results in decreased expression of MNX1 protein CTD PMID:21296659 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465 		JBrowse link
G Msln mesothelin increases expression EXP bromochloroacetic acid results in increased expression of MSLN mRNA CTD PMID:16460773 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP bromochloroacetic acid results in increased expression of MYC mRNA CTD PMID:16460773 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myf5 myogenic factor 5 decreases expression ISO bromochloroacetic acid results in decreased expression of MYF5 protein CTD PMID:21296659 NCBI chr 7:42,802,946...42,806,177
Ensembl chr 7:42,802,946...42,806,177 		JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO bromochloroacetic acid results in decreased expression of MYOD1 protein CTD PMID:21296659 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Nanog Nanog homeobox increases expression ISO bromochloroacetic acid results in increased expression of NANOG protein CTD PMID:21296659 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Neurod1 neuronal differentiation 1 increases expression ISO bromochloroacetic acid results in increased expression of NEUROD1 protein CTD PMID:21296659 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nodal nodal growth differentiation factor affects expression ISO bromochloroacetic acid affects the expression of NODAL protein CTD PMID:21296659 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Nog noggin increases expression ISO bromochloroacetic acid results in increased expression of NOG protein CTD PMID:21296659 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nppa natriuretic peptide A increases expression ISO bromochloroacetic acid results in increased expression of NPPA protein CTD PMID:21296659 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO bromochloroacetic acid results in increased expression of NR5A2 protein CTD PMID:21296659 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Nras NRAS proto-oncogene, GTPase increases expression EXP bromochloroacetic acid results in increased expression of NRAS mRNA CTD PMID:16460773 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 decreases expression ISO bromochloroacetic acid results in decreased expression of OLIG2 protein CTD PMID:21296659 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152 		JBrowse link
G Pax6 paired box 6 increases expression ISO bromochloroacetic acid results in increased expression of PAX6 protein CTD PMID:21296659 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression ISO bromochloroacetic acid results in decreased expression of IPF1 protein CTD PMID:21296659 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Podxl podocalyxin-like increases expression ISO bromochloroacetic acid results in increased expression of PODXL protein CTD PMID:21296659 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO bromochloroacetic acid results in increased expression of POU5F1 protein CTD PMID:21296659 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A decreases expression EXP bromochloroacetic acid results in decreased expression of PPP1R12A mRNA CTD PMID:16460773 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases expression EXP bromochloroacetic acid results in increased expression of PPP2R2B mRNA CTD PMID:16460773 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP bromochloroacetic acid results in increased expression of PRKCZ mRNA CTD PMID:16460773 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Rala RAS like proto-oncogene A decreases expression EXP bromochloroacetic acid results in decreased expression of RALA mRNA CTD PMID:16460773 NCBI chr17:47,092,163...47,145,192
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Rest RE1-silencing transcription factor decreases expression ISO bromochloroacetic acid results in decreased expression of REST protein CTD PMID:21296659 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Sema3a semaphorin 3A decreases expression ISO bromochloroacetic acid results in decreased expression of SEMA3A protein CTD PMID:21296659 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression ISO bromochloroacetic acid results in decreased expression of SFRP2 protein CTD PMID:21296659 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression ISO bromochloroacetic acid results in decreased expression of SOX17 protein CTD PMID:21296659 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox2 SRY-box transcription factor 2 affects expression ISO bromochloroacetic acid affects the expression of SOX2 protein CTD PMID:21296659 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sst somatostatin increases expression ISO bromochloroacetic acid results in increased expression of SST protein CTD PMID:21296659 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression ISO bromochloroacetic acid results in decreased expression of SYCP3 protein CTD PMID:21296659 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511 		JBrowse link
G Syp synaptophysin decreases expression ISO bromochloroacetic acid results in decreased expression of SYP protein CTD PMID:21296659 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tat tyrosine aminotransferase decreases expression ISO bromochloroacetic acid results in decreased expression of TAT protein CTD PMID:21296659 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tbxt T-box transcription factor T increases expression ISO bromochloroacetic acid results in increased expression of T protein CTD PMID:21296659 NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864 		JBrowse link
G Tert telomerase reverse transcriptase increases expression ISO bromochloroacetic acid results in increased expression of TERT protein CTD PMID:21296659 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression EXP bromochloroacetic acid results in decreased expression of TGFB2 mRNA CTD PMID:16460773 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression EXP bromochloroacetic acid results in decreased expression of TGFB3 mRNA CTD PMID:16460773 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression EXP bromochloroacetic acid results in increased expression of TGFBR2 mRNA CTD PMID:16460773 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Th tyrosine hydroxylase affects expression ISO bromochloroacetic acid affects the expression of TH protein CTD PMID:21296659 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP bromochloroacetic acid promotes the reaction [Bromates results in increased phosphorylation of TP53 protein] CTD PMID:21864635 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Utf1 undifferentiated embryonic cell transcription factor 1 affects expression ISO bromochloroacetic acid affects the expression of UTF1 protein CTD PMID:21296659 NCBI chr 1:194,740,339...194,741,465
Ensembl chr 1:194,740,339...194,741,465 		JBrowse link
G Wnt4 Wnt family member 4 increases expression EXP bromochloroacetic acid results in increased expression of WNT4 mRNA CTD PMID:16460773 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO bromochloroacetic acid results in decreased expression of WT1 protein CTD PMID:21296659 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xist X inactive specific transcript decreases expression ISO bromochloroacetic acid results in decreased expression of XIST protein CTD PMID:21296659 NCBI chr  X:68,474,987...68,492,500 JBrowse link
G Zfp42 zinc finger protein 42 increases expression ISO bromochloroacetic acid results in increased expression of ZFP42 protein CTD PMID:21296659 NCBI chr16:48,836,463...48,845,443
Ensembl chr16:48,836,648...48,845,401 		JBrowse link
dibromoacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 increases expression ISO dibromoacetic acid results in increased expression of ATF2 mRNA CTD PMID:29155130 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO dibromoacetic acid results in decreased expression of BCL2 mRNA CTD PMID:18628252 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases expression ISO dibromoacetic acid results in increased expression of CASP3 protein modified form CTD PMID:29155130 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ces3a carboxylesterase 3a decreases expression EXP dibromoacetic acid results in decreased expression of CES3 mRNA CTD PMID:21046364 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP dibromoacetic acid results in decreased expression of COL1A2 mRNA CTD PMID:21046364 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP17A1 mRNA CTD PMID:21046364 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP1B1 mRNA CTD PMID:21046364 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Dpt dermatopontin decreases expression EXP dibromoacetic acid results in decreased expression of DPT mRNA CTD PMID:21046364 NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases expression ISO dibromoacetic acid results in increased expression of ELK1 mRNA CTD PMID:29155130 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP dibromoacetic acid inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:10580743 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP dibromoacetic acid results in decreased expression of FADS1 mRNA CTD PMID:21046364 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO dibromoacetic acid results in increased expression of FAS mRNA; dibromoacetic acid results in increased expression of FAS protein CTD PMID:18628252 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO dibromoacetic acid results in increased expression of FASL protein CTD PMID:18628252 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP dibromoacetic acid results in decreased expression of HAO2 mRNA CTD PMID:21046364 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP dibromoacetic acid results in decreased expression of HBA-A2 mRNA CTD PMID:21046364 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP dibromoacetic acid results in decreased expression of HBB mRNA CTD PMID:21046364 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP dibromoacetic acid results in decreased expression of IGFBP7 mRNA CTD PMID:21046364 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Insl3 insulin-like 3 decreases expression EXP dibromoacetic acid results in decreased expression of INSL3 mRNA CTD PMID:21046364 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO dibromoacetic acid results in decreased methylation of MYC promoter CTD PMID:16014735 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression ISO dibromoacetic acid results in increased expression of TRAF2 mRNA CTD PMID:18628252 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      chemical role 19451
        donor 18913
          Bronsted acid 18794
            oxoacid 18768
              carbon oxoacid 18641
                carboxylic acid 18638
                  2-bromocarboxylic acid 145
                    2-bromodecanoic acid 0
                    2-bromohexadecanoic acid 20
                    bromochloroacetic acid 110
                    bromosuccinic acid 0
                    dibromoacetic acid 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      2-bromocarboxylic acid 145
                                        2-bromodecanoic acid 0
                                        2-bromohexadecanoic acid 20
                                        bromochloroacetic acid 110
                                        bromosuccinic acid 0
                                        dibromoacetic acid 20
paths to the root