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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dibromoacetic acid
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Accession:CHEBI:90124 term browser browse the term
Definition:A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are replaced by bromo groups.
Synonyms:related_synonym: 2,2-Dibromoacetic acid;   2,2-dibromoethanoic acid;   DBAA;   Dibromoethanoic acid;   Formula=C2H2Br2O2;   InChI=1S/C2H2Br2O2/c3-1(4)2(5)6/h1H,(H,5,6);   InChIKey=SIEILFNCEFEENQ-UHFFFAOYSA-N;   SMILES=C(Br)(Br)C(=O)O
 xref: CAS:631-64-1;   KEGG:C20123;   LIPID_MAPS_instance:LMFA01090076
 xref_mesh: MESH:C088674
 xref: PMID:23348848;   PMID:25556763;   PMID:25955755;   PMID:26052022;   PMID:26188195;   Reaxys:1700457


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dibromoacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 increases expression ISO dibromoacetic acid results in increased expression of ATF2 mRNA CTD PMID:29155130 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO dibromoacetic acid results in decreased expression of BCL2 mRNA CTD PMID:18628252 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 increases expression ISO dibromoacetic acid results in increased expression of CASP3 protein modified form CTD PMID:29155130 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ces3a carboxylesterase 3a decreases expression EXP dibromoacetic acid results in decreased expression of CES3 mRNA CTD PMID:21046364 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP dibromoacetic acid results in decreased expression of COL1A2 mRNA CTD PMID:21046364 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP17A1 mRNA CTD PMID:21046364 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP1B1 mRNA CTD PMID:21046364 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Dpt dermatopontin decreases expression EXP dibromoacetic acid results in decreased expression of DPT mRNA CTD PMID:21046364 NCBI chr13:77,122,926...77,151,646
Ensembl chr13:77,123,115...77,151,639
JBrowse link
G Elk1 ETS transcription factor ELK1 increases expression ISO dibromoacetic acid results in increased expression of ELK1 mRNA CTD PMID:29155130 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP dibromoacetic acid inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:10580743 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP dibromoacetic acid results in decreased expression of FADS1 mRNA CTD PMID:21046364 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO dibromoacetic acid results in increased expression of FAS mRNA; dibromoacetic acid results in increased expression of FAS protein CTD PMID:18628252 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression ISO dibromoacetic acid results in increased expression of FASL protein CTD PMID:18628252 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP dibromoacetic acid results in decreased expression of HAO2 mRNA CTD PMID:21046364 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP dibromoacetic acid results in decreased expression of HBA-A2 mRNA CTD PMID:21046364 NCBI chr10:15,323,830...15,324,677 JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP dibromoacetic acid results in decreased expression of HBB mRNA CTD PMID:21046364 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP dibromoacetic acid results in decreased expression of IGFBP7 mRNA CTD PMID:21046364 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
JBrowse link
G Insl3 insulin-like 3 decreases expression EXP dibromoacetic acid results in decreased expression of INSL3 mRNA CTD PMID:21046364 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO dibromoacetic acid results in decreased methylation of MYC promoter CTD PMID:16014735 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression ISO dibromoacetic acid results in increased expression of TRAF2 mRNA CTD PMID:18628252 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          apoptosis inducer 13236
            dibromoacetic acid 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        monocarboxylic acid 17636
                                          acetic acid 10853
                                            dibromoacetic acid 20
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