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Gene: Gdf3 (growth differentiation factor 3) Rattus norvegicus
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Symbol: Gdf3
Name: growth differentiation factor 3
Description: Predicted to have cytokine activity; protein kinase binding activity; and transforming growth factor beta receptor binding activity. Predicted to be involved in several processes, including anterior/posterior axis specification; regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to localize to the cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome and isolated microphthalmia 7. Orthologous to human GDF3 (growth differentiation factor 3); INTERACTS WITH 1,2-dimethylhydrazine; bisphenol A; Monobutylphthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: growth/differentiation factor 3; LOC500311; RGD1564178; similar to growth/differentiation factor GDF-3 precursor - mouse
Orthologs:
Homo sapiens (human) : GDF3 (growth differentiation factor 3)  HGNC  Alliance
Mus musculus (house mouse) : Gdf3 (growth differentiation factor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf3 (growth differentiation factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF3 (growth differentiation factor 3)
Canis lupus familiaris (dog) : GDF3 (growth differentiation factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf3 (growth differentiation factor 3)
Sus scrofa (pig) : GDF3 (growth differentiation factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04155,417,667 - 155,422,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,417,004 - 155,421,998 (-)Ensembl
Rnor_5.04222,441,866 - 222,445,551 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44159,064,054 - 159,067,854 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4144,650,730 - 144,655,147 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gdf3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564178
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.