CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: bromohydrocarbon
Accession: CHEBI:22926
browse the term
Definition: A compound derived from a hydrocarbon by replacing a hydrogen atom with a bromine atom.
Synonyms: related_synonym: brominated hydrocarbons; bromohydrocarbons
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Acsm1
acyl-CoA synthetase medium-chain family member 1
increases expression
ISO
Ethylene Dibromide results in increased expression of ACSM1 mRNA
CTD
PMID:17311802
NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495
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Arid3a
AT-rich interaction domain 3A
increases expression
ISO
Ethylene Dibromide results in increased expression of ARID3A mRNA
CTD
PMID:15612046
NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599
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Ces1d
carboxylesterase 1D
increases expression
ISO
Ethylene Dibromide results in increased expression of CES1 mRNA
CTD
PMID:17311802
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases metabolic processing increases oxidation
ISO
CYP2E1 protein results in increased metabolism of Ethylene Dibromide CYP2E1 protein results in increased oxidation of Ethylene Dibromide
CTD
PMID:1664256 PMID:10841534 PMID:18350910
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Ecm1
extracellular matrix protein 1
decreases expression
ISO
Ethylene Dibromide results in decreased expression of ECM1 mRNA
CTD
PMID:15612046
NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
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Ephx1
epoxide hydrolase 1
decreases expression
ISO
Ethylene Dibromide results in decreased expression of EPHX1 mRNA
CTD
PMID:17311802
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Fgfrl1
fibroblast growth factor receptor-like 1
decreases expression
ISO
Ethylene Dibromide results in decreased expression of FGFRL1 protein
CTD
PMID:22434383
NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928
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Ggt1
gamma-glutamyltransferase 1
increases activity multiple interactions
ISO
Ethylene Dibromide results in increased activity of GGT1 protein Phentolamine inhibits the reaction [Ethylene Dibromide results in increased activity of GGT1 protein]; Phenylephrine promotes the reaction [Ethylene Dibromide results in increased activity of GGT1 protein]
CTD
PMID:12628311
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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Gstt1
glutathione S-transferase theta 1
multiple interactions increases activity affects response to substance increases glutathionylation
ISO EXP
GSTT1 gene SNP inhibits the reaction [GSTT1 protein results in increased glutathionylation of Ethylene Dibromide]; GSTT1 protein affects the metabolism of and results in increased activity of Ethylene Dibromide GSTT1 protein results in increased activity of Ethylene Dibromide GSTT1 protein results in increased metabolism of and results in increased activity of Ethylene Dibromide GSTT1 protein affects the susceptibility to Ethylene Dibromide
CTD
PMID:8565128 PMID:10413528 PMID:12505322 PMID:12902151 PMID:19664997 PMID:21781954 More...
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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Gtf2ird1
GTF2I repeat domain containing 1
decreases expression
ISO
Ethylene Dibromide results in decreased expression of GTF2IRD1 protein
CTD
PMID:22434383
NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
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Krt10
keratin 10
decreases expression
ISO
Ethylene Dibromide results in decreased expression of KRT10 protein
CTD
PMID:22434383
NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
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Lef1
lymphoid enhancer binding factor 1
decreases expression
ISO
Ethylene Dibromide results in decreased expression of LEF1 mRNA
CTD
PMID:15612046
NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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Mapk10
mitogen activated protein kinase 10
increases expression
ISO
Ethylene Dibromide results in increased expression of MAPK10 mRNA
CTD
PMID:15612046
NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
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Mgmt
O-6-methylguanine-DNA methyltransferase
multiple interactions increases response to substance affects binding
ISO
Ethylene Dibromide binds to and results in decreased activity of MGMT protein; MGMT protein affects the metabolism of and results in increased activity of Ethylene Dibromide; MGMT protein results in increased activity of and results in increased susceptibility to Ethylene Dibromide MGMT protein results in increased susceptibility to Ethylene Dibromide Ethylene Dibromide binds to MGMT protein
CTD
PMID:10894884 PMID:12151404 PMID:14645247 PMID:17226938
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity
ISO
Ethylene Dibromide results in increased activity of NFE2L2 protein
CTD
PMID:30114225 PMID:30203046
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nherf1
NHERF family PDZ scaffold protein 1
increases expression
ISO
Ethylene Dibromide results in increased expression of NHERF1 protein
CTD
PMID:22434383
NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
Ethylene Dibromide results in increased expression of NQO1 mRNA
CTD
PMID:17311802
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Odc1
ornithine decarboxylase 1
increases activity
EXP
Ethylene Dibromide results in increased activity of ODC1 protein
CTD
PMID:3801022
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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Pard3
par-3 family cell polarity regulator
increases expression
ISO
Ethylene Dibromide results in increased expression of PARD3 protein
CTD
PMID:22434383
NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
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Pld3
phospholipase D family, member 3
increases expression
ISO
Ethylene Dibromide results in increased expression of PLD3 mRNA
CTD
PMID:15612046
NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072
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Ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
decreases expression
ISO
Ethylene Dibromide results in decreased expression of PPP1R1C mRNA
CTD
PMID:15612046
NCBI chr 3:64,616,700...64,719,696
Ensembl chr 3:64,616,700...64,724,104
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Rad18
RAD18 E3 ubiquitin protein ligase
decreases expression
ISO
Ethylene Dibromide results in decreased expression of RAD18 protein
CTD
PMID:22434383
NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
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St7l
suppression of tumorigenicity 7-like
decreases expression
ISO
Ethylene Dibromide results in decreased expression of ST7L mRNA
CTD
PMID:15612046
NCBI chr 2:192,364,594...192,434,414
Ensembl chr 2:192,364,594...192,487,190
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Tcfl5
transcription factor like 5
increases expression
ISO
Ethylene Dibromide results in increased expression of TCFL5 mRNA
CTD
PMID:15612046
NCBI chr 3:167,734,471...167,754,174
Ensembl chr 3:167,734,473...167,754,282
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Tnf
tumor necrosis factor
increases expression
EXP
Ethylene dibromide increases expression of Tnf mRNA in liver
RGD
PMID:7943184
RGD:14995476
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tp63
tumor protein p63
increases expression
ISO
Ethylene Dibromide results in increased expression of TRP63 mRNA
CTD
PMID:15612046
NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
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Tph1
tryptophan hydroxylase 1
increases expression
ISO
Ethylene Dibromide results in increased expression of TPH1 mRNA
CTD
PMID:15612046
NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
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Trpv2
transient receptor potential cation channel, subfamily V, member 2
increases expression
ISO
Ethylene Dibromide results in increased expression of TRPV2 mRNA
CTD
PMID:15612046
NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
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Abat
4-aminobutyrate aminotransferase
decreases expression
EXP
1-bromopropane results in decreased expression of ABAT protein
CTD
PMID:21925529
NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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Anp32a
acidic nuclear phosphoprotein 32 family member A
increases expression
EXP
1-bromopropane results in increased expression of ANP32A protein
CTD
PMID:21925529
NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443
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Arg1
arginase 1
increases expression multiple interactions
EXP
1-bromopropane results in increased expression of ARG1 protein allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of ARG1 protein]
CTD
PMID:30247689
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Atp5pd
ATP synthase peripheral stalk subunit d
decreases expression
EXP
1-bromopropane results in decreased expression of ATP5PD protein
CTD
PMID:21925529
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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Bcl2l1
Bcl2-like 1
decreases expression
EXP ISO
1-bromopropane results in decreased expression of BCL2L1 mRNA
CTD
PMID:16815550
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bdnf
brain-derived neurotrophic factor
multiple interactions decreases expression
ISO EXP
1-bromopropane inhibits the reaction [Bucladesine results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein] 1-bromopropane results in decreased expression of BDNF mRNA
CTD
PMID:19189864 PMID:23266320
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Casp3
caspase 3
increases cleavage
EXP
1-bromopropane results in increased cleavage of CASP3 protein
CTD
PMID:30247689
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
decreases expression
EXP
1-bromopropane results in decreased expression of CAT mRNA
CTD
PMID:27452781
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccn5
cellular communication network factor 5
multiple interactions increases expression
ISO
ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CCN5 mRNA]
CTD
PMID:23384675
NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636
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Ckb
creatine kinase B
decreases expression
EXP
1-bromopropane results in decreased expression of CKB protein
CTD
PMID:21925529
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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Ckmt1
creatine kinase, mitochondrial 1
decreases expression
EXP
1-bromopropane results in decreased expression of CKMT1 protein
CTD
PMID:21925529
NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758
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Creb1
cAMP responsive element binding protein 1
multiple interactions
ISO
1-bromopropane results in decreased phosphorylation of and results in decreased activity of CREB1 protein
CTD
PMID:19189864
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Cxcl12
C-X-C motif chemokine ligand 12
increases expression multiple interactions
ISO
1-bromopropane results in increased expression of CXCL12 mRNA ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CXCL12 mRNA]
CTD
PMID:23384675
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Cybb
cytochrome b-245 beta chain
increases expression
EXP
1-bromopropane results in increased expression of CYBB mRNA; 1-bromopropane results in increased expression of CYBB protein
CTD
PMID:27452781
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases response to substance increases expression multiple interactions
ISO EXP
CYP2E1 protein results in increased susceptibility to 1-bromopropane 1-bromopropane results in increased expression of CYP2E1 allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1]
CTD
PMID:19638432 PMID:30247689
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Drd1
dopamine receptor D1
decreases expression
EXP
1-bromopropane results in decreased expression of DRD1 mRNA
CTD
PMID:19576243
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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Drd2
dopamine receptor D2
decreases expression
EXP
1-bromopropane results in decreased expression of DRD2 mRNA
CTD
PMID:19576243
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Ech1
enoyl-CoA hydratase 1
decreases expression
EXP
1-bromopropane results in decreased expression of ECH1 protein
CTD
PMID:21925529
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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Esr1
estrogen receptor 1
multiple interactions
ISO
ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CCN5 mRNA]; ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CXCL12 mRNA]
CTD
PMID:23384675
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
increases expression
ISO
1-bromopropane results in increased expression of ESR2 protein alternative form
CTD
PMID:27634370
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
decreases expression
EXP
1-bromopropane results in decreased expression of GABRA1 mRNA
CTD
PMID:19576243
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
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Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
increases expression
EXP
1-bromopropane results in increased expression of GABRG2 mRNA
CTD
PMID:19576243
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
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Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression multiple interactions
ISO
1-bromopropane results in increased expression of GCLC mRNA NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLC mRNA]
CTD
PMID:20211940
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gclm
glutamate cysteine ligase, modifier subunit
multiple interactions increases expression
ISO
NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLM mRNA]
CTD
PMID:20211940
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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Gda
guanine deaminase
decreases expression
EXP
1-bromopropane results in decreased expression of GDA protein
CTD
PMID:21925529
NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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Gpt
glutamic--pyruvic transaminase
increases activity
ISO
1-bromopropane results in increased activity of GPT protein
CTD
PMID:17265426
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Gria1
glutamate ionotropic receptor AMPA type subunit 1
increases expression
EXP
1-bromopropane results in increased expression of GRIA1 mRNA
CTD
PMID:32715571
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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Gsr
glutathione-disulfide reductase
increases expression multiple interactions decreases activity
ISO EXP
1-bromopropane results in increased expression of GSR mRNA NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GSR mRNA] 1-bromopropane results in decreased activity of GSR protein
CTD
PMID:20211940 PMID:23395825
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Gsta3
glutathione S-transferase alpha 3
increases expression
EXP
1-bromopropane results in increased expression of GSTA3 protein
CTD
PMID:21925529
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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Gstp1
glutathione S-transferase pi 1
increases expression
EXP
1-bromopropane results in increased expression of GSTP1 protein
CTD
PMID:21925529
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO
1-bromopropane results in increased expression of HMOX1 mRNA NFE2L2 promotes the reaction [1-bromopropane results in increased expression of HMOX1 mRNA]
CTD
PMID:20211940
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
decreases expression
EXP
1-bromopropane results in decreased expression of HNRNPH1 protein
CTD
PMID:21925529
NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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Hspa5
heat shock protein family A (Hsp70) member 5
increases expression
EXP ISO
1-bromopropane results in increased expression of HSPA5 protein
CTD
PMID:21925529 PMID:27421776
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hspd1
heat shock protein family D (Hsp60) member 1
increases expression
EXP
1-bromopropane results in increased expression of HSPD1 protein
CTD
PMID:21925529
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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Htr1a
5-hydroxytryptamine receptor 1A
decreases expression
EXP
1-bromopropane results in decreased expression of HTR1A mRNA
CTD
PMID:19576243
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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Htr2a
5-hydroxytryptamine receptor 2A
decreases expression
EXP
1-bromopropane results in decreased expression of HTR2A mRNA
CTD
PMID:19576243
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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Htr2c
5-hydroxytryptamine receptor 2C
increases expression
EXP
1-bromopropane results in increased expression of HTR2C mRNA
CTD
PMID:19576243
NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287
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Htr3a
5-hydroxytryptamine receptor 3A
affects expression
EXP
1-bromopropane affects the expression of HTR3A mRNA
CTD
PMID:19576243
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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Il1b
interleukin 1 beta
multiple interactions increases expression increases secretion
ISO
1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] 1-bromopropane results in increased expression of IL1B mRNA 1-bromopropane results in increased secretion of IL1B protein
CTD
PMID:16815550 PMID:18164123
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
increases secretion increases expression
ISO
1-bromopropane results in increased secretion of IL6 protein 1-bromopropane results in increased expression of IL6 mRNA
CTD
PMID:18164123
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation multiple interactions
ISO
1-bromopropane results in increased phosphorylation of MAPK1 protein MAPK1 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD
PMID:18164123 PMID:22353212
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
increases phosphorylation multiple interactions
ISO
1-bromopropane results in increased phosphorylation of MAPK3 protein MAPK3 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD
PMID:18164123 PMID:22353212
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions decreases expression decreases response to substance
ISO EXP
NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLC mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLM mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GSR mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of HMOX1 mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of NQO1 mRNA] 1-bromopropane results in decreased expression of NFE2L2 mRNA NFE2L2 results in decreased susceptibility to 1-bromopropane
CTD
PMID:20211940 PMID:27452781
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]] 1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]; MAPK1 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]; MAPK3 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD
PMID:16815550 PMID:18164123
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkbia
NFKB inhibitor alpha
multiple interactions increases degradation
ISO
1-bromopropane inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] 1-bromopropane results in increased degradation of NFKBIA protein
CTD
PMID:16815550 PMID:18164123
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nos2
nitric oxide synthase 2
multiple interactions increases expression
ISO EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [1-bromopropane results in increased expression of NOS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [1-bromopropane results in increased expression of NOS2 mRNA] 1-bromopropane results in increased expression of NOS2 protein allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of NOS2 protein]
CTD
PMID:18164123 PMID:30247689
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions
ISO
1-bromopropane results in increased expression of NQO1 mRNA NFE2L2 promotes the reaction [1-bromopropane results in increased expression of NQO1 mRNA]
CTD
PMID:20211940
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
decreases expression
EXP
1-bromopropane results in decreased expression of NR3C1 mRNA
CTD
PMID:23266320
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Park7
Parkinsonism associated deglycase
decreases expression
EXP
1-bromopropane results in decreased expression of PARK7 protein
CTD
PMID:21925529
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
G
Phgdh
phosphoglycerate dehydrogenase
increases expression
EXP
1-bromopropane results in increased expression of PHGDH protein
CTD
PMID:21925529
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
G
Pmpcb
peptidase, mitochondrial processing subunit beta
decreases expression
EXP
1-bromopropane results in decreased expression of PMPCB protein
CTD
PMID:21925529
NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367
G
Psma1
proteasome 20S subunit alpha 1
decreases expression
EXP
1-bromopropane results in decreased expression of PSMA1 protein
CTD
PMID:21925529
NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions increases expression
ISO
1-bromopropane results in increased expression of and results in increased activity of PTGS2 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [1-bromopropane results in increased expression of PTGS2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [1-bromopropane results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [1-bromopropane results in increased expression of PTGS2 protein] 1-bromopropane results in increased expression of PTGS2 mRNA
CTD
PMID:22353212
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ran
RAN, member RAS oncogene family
increases expression
EXP ISO
1-bromopropane results in increased expression of RAN protein
CTD
PMID:21925529 PMID:27421776
NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
G
Rbfox3
RNA binding fox-1 homolog 3
multiple interactions increases expression
EXP
allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of RBFOX3 protein]
CTD
PMID:30247689
NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions affects localization
ISO EXP
1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]] 1-bromopropane results in increased phosphorylation of and results in increased activity of RELA protein; allyl sulfide inhibits the reaction [1-bromopropane results in increased phosphorylation of and results in increased activity of RELA protein] 1-bromopropane affects the localization of RELA protein 1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]; MAPK1 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]; MAPK3 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD
PMID:16815550 PMID:18164123 PMID:30247689
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Scn1a
sodium voltage-gated channel alpha subunit 1
increases expression
EXP
1-bromopropane results in increased expression of SCN1A mRNA
CTD
PMID:32715571
NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699
G
Sod1
superoxide dismutase 1
decreases expression
EXP
1-bromopropane results in decreased expression of SOD1 mRNA
CTD
PMID:27452781
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sod2
superoxide dismutase 2
decreases expression
EXP
1-bromopropane results in decreased expression of SOD2 mRNA
CTD
PMID:27452781
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Tnf
tumor necrosis factor
increases expression increases secretion
ISO
1-bromopropane results in increased expression of TNF mRNA 1-bromopropane results in increased secretion of TNF protein
CTD
PMID:18164123
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tpi1
triosephosphate isomerase 1
increases expression decreases expression
EXP
1-bromopropane results in increased expression of TPI1 protein 1-bromopropane results in decreased expression of TPI1 protein
CTD
PMID:21925529
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
G
Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
2,4,5,2',4',5'-hexabromobiphenyl binds to and results in increased activity of AHR protein
CTD
PMID:15099731
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Gja1
gap junction protein, alpha 1
multiple interactions
ISO
[Dieldrin co-treated with 2,4,5,2',4',5'-hexabromobiphenyl] results in decreased expression of GJA1 protein
CTD
PMID:8820588
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Cyp11b3
cytochrome P450, family 11, subfamily b, polypeptide 3
decreases expression
ISO
2,6-dibromophenol results in decreased expression of CYP11B2 mRNA
CTD
PMID:17447562
NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
ISO
2,6-dibromophenol results in decreased expression of CYP17A1 mRNA
CTD
PMID:17447562
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
G
Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
decreases expression
ISO
2,6-dibromophenol results in decreased expression of HSD17B1 mRNA
CTD
PMID:17447562
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
decreases expression
ISO
2,6-dibromophenol results in decreased expression of HSD17B4 mRNA
CTD
PMID:17447562
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
G
Hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
increases expression
ISO
2,6-dibromophenol results in increased expression of HSD3B2 mRNA
CTD
PMID:17447562
NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
G
Star
steroidogenic acute regulatory protein
decreases expression
ISO
2,6-dibromophenol results in decreased expression of STAR mRNA
CTD
PMID:17447562
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
G
Gja1
gap junction protein, alpha 1
decreases activity
EXP
bromoxynil results in decreased activity of GJA1 protein
CTD
PMID:20510257
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Ttr
transthyretin
affects binding
EXP
bromoxynil binds to TTR protein
CTD
PMID:2043046
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
G
Abcb11
ATP binding cassette subfamily B member 11
decreases activity multiple interactions
ISO
Benzbromarone results in decreased activity of ABCB11 protein Benzbromarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD
PMID:20829430 PMID:23956101 PMID:24014644 PMID:28437613
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
G
Abcb1a
ATP binding cassette subfamily B member 1A
affects expression
EXP
Benzbromarone affects the expression of ABCB1A mRNA
CTD
PMID:19483382
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
G
Abcb4
ATP binding cassette subfamily B member 4
decreases activity
ISO
Benzbromarone results in decreased activity of ABCB4 protein
CTD
PMID:28437613
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
G
Abcc1
ATP binding cassette subfamily C member 1
multiple interactions affects activity
ISO
Benzbromarone inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Benzbromarone inhibits the reaction [ABCC1 protein results in increased secretion of Daunorubicin] Benzbromarone affects the activity of ABCC1 protein
CTD
PMID:9096673 PMID:9334814 PMID:15041471 PMID:16101123
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
G
Abcc2
ATP binding cassette subfamily C member 2
multiple interactions decreases activity
EXP ISO
[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD
PMID:19782883 PMID:19853032 PMID:22646477 PMID:31348918
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Abcc3
ATP binding cassette subfamily C member 3
multiple interactions
ISO
Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; yu ping feng san inhibits the reaction [Benzbromarone results in increased activity of ABCC3 protein]
CTD
PMID:31348918 PMID:34135758
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
G
Abcc5
ATP binding cassette subfamily C member 5
multiple interactions
ISO
Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD
PMID:31348918
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
G
Abcc6
ATP binding cassette subfamily C member 6
multiple interactions affects expression decreases activity
ISO EXP
Benzbromarone inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione] Benzbromarone affects the expression of ABCC6 mRNA Benzbromarone results in decreased activity of ABCC6 protein
CTD
PMID:11880368 PMID:14667841 PMID:19483382
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
G
Abcg5
ATP binding cassette subfamily G member 5
affects expression
EXP
Benzbromarone affects the expression of ABCG5 mRNA
CTD
PMID:19483382
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
G
Abhd1
abhydrolase domain containing 1
affects expression
EXP
Benzbromarone affects the expression of ABHD1 mRNA
CTD
PMID:19483382
NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
G
Abhd14b
abhydrolase domain containing 14b
affects expression
EXP
Benzbromarone affects the expression of ABHD14B mRNA
CTD
PMID:19483382
NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
G
Abhd17a
abhydrolase domain containing 17A, depalmitoylase
affects expression
EXP
Benzbromarone affects the expression of ABHD17A mRNA
CTD
PMID:19483382
NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
G
Acaca
acetyl-CoA carboxylase alpha
affects expression
EXP
Benzbromarone affects the expression of ACACA mRNA
CTD
PMID:19483382
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
G
Acadl
acyl-CoA dehydrogenase, long chain
affects expression
EXP
Benzbromarone affects the expression of ACADL mRNA
CTD
PMID:19483382
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
G
Ace2
angiotensin converting enzyme 2
decreases expression
ISO
Benzbromarone results in decreased expression of ACE2 mRNA
CTD
PMID:32808185
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
G
Aco1
aconitase 1
affects expression
EXP
Benzbromarone affects the expression of ACO1 mRNA
CTD
PMID:19483382
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
G
Aco2
aconitase 2
affects expression
EXP
Benzbromarone affects the expression of ACO2 mRNA
CTD
PMID:19483382
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
G
Acot12
acyl-CoA thioesterase 12
affects expression
EXP
Benzbromarone affects the expression of ACOT12 mRNA
CTD
PMID:19483382
NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
G
Acot4
acyl-CoA thioesterase 4
affects expression
EXP
Benzbromarone affects the expression of ACOT4 mRNA
CTD
PMID:19483382
NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
G
Adam15
ADAM metallopeptidase domain 15
affects expression
EXP
Benzbromarone affects the expression of ADAM15 mRNA
CTD
PMID:19483382
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
G
Add1
adducin 1
affects expression
EXP
Benzbromarone affects the expression of ADD1 mRNA
CTD
PMID:19483382
NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
G
Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
affects expression
EXP
Benzbromarone affects the expression of ADH4 mRNA
CTD
PMID:19483382
NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
G
Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions increases expression
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [Benzbromarone results in increased expression of ADIPOQ mRNA] Benzbromarone results in increased expression of ADIPOQ protein
CTD
PMID:19048458 PMID:21329621
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
G
Adtrp
androgen-dependent TFPI-regulating protein
affects expression
EXP
Benzbromarone affects the expression of ADTRP mRNA
CTD
PMID:19483382
NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
G
Afm
afamin
affects expression
EXP
Benzbromarone affects the expression of AFM mRNA
CTD
PMID:19483382
NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870
G
Agt
angiotensinogen
affects expression
EXP
Benzbromarone affects the expression of AGT mRNA
CTD
PMID:19483382
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
G
Agtr1a
angiotensin II receptor, type 1a
affects expression
EXP
Benzbromarone affects the expression of AGTR1A mRNA
CTD
PMID:19483382
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
G
Akr1a1
aldo-keto reductase family 1 member A1
affects expression
EXP
Benzbromarone affects the expression of AKR1A1 mRNA
CTD
PMID:19483382
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
G
Akr1c1
aldo-keto reductase family 1, member C1
multiple interactions
ISO
Benzbromarone binds to and results in decreased activity of AKR1C1 protein
CTD
PMID:12604236
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
G
Akr1c2
aldo-keto reductase family 1, member C2
decreases activity
ISO
Benzbromarone results in decreased activity of AKR1C2 protein
CTD
PMID:12604236
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
G
Akr1c3
aldo-keto reductase family 1, member C3
decreases activity
ISO
Benzbromarone results in decreased activity of AKR1C3 protein
CTD
PMID:12604236
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
G
Akr7a2
aldo-keto reductase family 7, member A2
affects expression
EXP
Benzbromarone affects the expression of AKR7A2 mRNA
CTD
PMID:19483382
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
G
Akr7a3
aldo-keto reductase family 7 member A3
affects expression
EXP
Benzbromarone affects the expression of AKR7A3 mRNA
CTD
PMID:19483382
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
G
Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
EXP
Benzbromarone affects the expression of ALDH1A1 mRNA
CTD
PMID:19483382
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
G
Aldh2
aldehyde dehydrogenase 2 family member
affects expression
EXP
Benzbromarone affects the expression of ALDH2 mRNA
CTD
PMID:19483382
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
G
Alkbh7
alkB homolog 7
affects expression
EXP
Benzbromarone affects the expression of ALKBH7 mRNA
CTD
PMID:19483382
NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
G
Ap2m1
adaptor related protein complex 2 subunit mu 1
affects expression
EXP
Benzbromarone affects the expression of AP2M1 mRNA
CTD
PMID:19483382
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
G
Apcs
amyloid P component, serum
affects expression
EXP
Benzbromarone affects the expression of APCS mRNA
CTD
PMID:19483382
NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
G
Apoa4
apolipoprotein A4
affects expression
EXP
Benzbromarone affects the expression of APOA4 mRNA
CTD
PMID:19483382
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
G
Apoh
apolipoprotein H
affects expression
EXP
Benzbromarone affects the expression of APOH mRNA
CTD
PMID:19483382
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
G
Apool
apolipoprotein O-like
affects expression
EXP
Benzbromarone affects the expression of APOOL mRNA
CTD
PMID:19483382
NCBI chr X:77,377,723...77,443,672
Ensembl chr X:77,377,781...77,443,900
G
Arg1
arginase 1
affects expression
EXP
Benzbromarone affects the expression of ARG1 mRNA
CTD
PMID:19483382
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
G
Arl6ip1
ADP-ribosylation factor like GTPase 6 interacting protein 1
affects expression
EXP
Benzbromarone affects the expression of ARL6IP1 mRNA
CTD
PMID:19483382
NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
G
Asgr2
asialoglycoprotein receptor 2
affects expression
EXP
Benzbromarone affects the expression of ASGR2 mRNA
CTD
PMID:19483382
NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
G
Atf5
activating transcription factor 5
affects expression
EXP
Benzbromarone affects the expression of ATF5 mRNA
CTD
PMID:19483382
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
G
Atp5f1e
ATP synthase F1 subunit epsilon
affects expression
EXP
Benzbromarone affects the expression of ATP5F1E mRNA
CTD
PMID:19483382
NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
G
Atp6ap2
ATPase H+ transporting accessory protein 2
affects expression
EXP
Benzbromarone affects the expression of ATP6AP2 mRNA
CTD
PMID:19483382
NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
G
Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
EXP
Benzbromarone affects the expression of ATP6V1A mRNA
CTD
PMID:19483382
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
G
Atp6v1f
ATPase H+ transporting V1 subunit F
affects expression
EXP
Benzbromarone affects the expression of ATP6V1F mRNA
CTD
PMID:19483382
NCBI chr 4:58,067,666...58,070,628
G
Baat
bile acid CoA:amino acid N-acyltransferase
affects expression
EXP
Benzbromarone affects the expression of BAAT mRNA
CTD
PMID:19483382
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
G
Bcl6b
BCL6B, transcription repressor
affects expression
EXP
Benzbromarone affects the expression of BCL6B mRNA
CTD
PMID:19483382
NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
G
Bltp3b
bridge-like lipid transfer protein family member 3B
affects expression
EXP
Benzbromarone affects the expression of BLTP3B mRNA
CTD
PMID:19483382
NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720
G
Bmf
Bcl2 modifying factor
affects expression
EXP
Benzbromarone affects the expression of BMF mRNA
CTD
PMID:19483382
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
G
Bnip3
BCL2 interacting protein 3
affects expression
EXP
Benzbromarone affects the expression of BNIP3 mRNA
CTD
PMID:19483382
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
G
Btf3
basic transcription factor 3
affects expression
EXP
Benzbromarone affects the expression of BTF3 mRNA
CTD
PMID:19483382
NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
G
C1qbp
complement C1q binding protein
affects expression
EXP
Benzbromarone affects the expression of C1QBP mRNA
CTD
PMID:19483382
NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
G
C1s
complement C1s
affects expression
EXP
Benzbromarone affects the expression of C1S mRNA
CTD
PMID:19483382
NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
G
C2cd2
C2 calcium-dependent domain containing 2
affects expression
EXP
Benzbromarone affects the expression of C2CD2 mRNA
CTD
PMID:19483382
NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
G
C4bpa
complement component 4 binding protein, alpha
affects expression
EXP
Benzbromarone affects the expression of C4BPA mRNA
CTD
PMID:19483382
NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
G
C7
complement C7
affects expression
EXP
Benzbromarone affects the expression of C7 mRNA
CTD
PMID:19483382
NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
G
C8b
complement C8 beta chain
affects expression
EXP
Benzbromarone affects the expression of C8B mRNA
CTD
PMID:19483382
NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
G
Cadps2
calcium dependent secretion activator 2
affects expression
EXP
Benzbromarone affects the expression of CADPS2 mRNA
CTD
PMID:19483382
NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
G
Caprin1
cell cycle associated protein 1
affects expression
EXP
Benzbromarone affects the expression of CAPRIN1 mRNA
CTD
PMID:19483382
NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
G
Car2
carbonic anhydrase 2
affects expression
EXP
Benzbromarone affects the expression of CA2 mRNA
CTD
PMID:19483382
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
G
Car3
carbonic anhydrase 3
affects expression
EXP
Benzbromarone affects the expression of CAR3 mRNA
CTD
PMID:19483382
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
G
Casp3
caspase 3
affects expression
EXP
Benzbromarone affects the expression of CASP3 mRNA
CTD
PMID:19483382
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Cat
catalase
increases activity
EXP
Benzbromarone results in increased activity of CAT protein
CTD
PMID:2260096
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cbr1
carbonyl reductase 1
affects expression
EXP
Benzbromarone affects the expression of CBR1 mRNA
CTD
PMID:19483382
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
G
Cd36
CD36 molecule
increases expression
ISO
Benzbromarone results in increased expression of CD36 mRNA
CTD
PMID:19048458
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cdo1
cysteine dioxygenase type 1
affects expression
EXP
Benzbromarone affects the expression of CDO1 mRNA
CTD
PMID:19483382
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
G
Cept1
choline/ethanolamine phosphotransferase 1
affects expression
EXP
Benzbromarone affects the expression of CEPT1 mRNA
CTD
PMID:19483382
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
G
Ces2h
carboxylesterase 2H
affects expression
EXP
Benzbromarone affects the expression of CES2 mRNA
CTD
PMID:19483382
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
G
Cfi
complement factor I
affects expression
EXP
Benzbromarone affects the expression of CFI mRNA
CTD
PMID:19483382
NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
G
Chp1
calcineurin-like EF-hand protein 1
affects expression
EXP
Benzbromarone affects the expression of CHP1 mRNA
CTD
PMID:19483382
NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
G
Cisd1
CDGSH iron sulfur domain 1
affects expression
EXP
Benzbromarone affects the expression of CISD1 mRNA
CTD
PMID:19483382
NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
G
Clcn4
chloride voltage-gated channel 4
affects expression
EXP
Benzbromarone affects the expression of CLCN4 mRNA
CTD
PMID:19483382
NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238
G
Clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
affects expression
EXP
Benzbromarone affects the expression of CLPP mRNA
CTD
PMID:19483382
NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
G
Clptm1l
CLPTM1-like
affects expression
EXP
Benzbromarone affects the expression of CLPTM1L mRNA
CTD
PMID:19483382
NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
G
Cmbl
carboxymethylenebutenolidase homolog
affects expression
EXP
Benzbromarone affects the expression of CMBL mRNA
CTD
PMID:19483382
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
G
Cmpk1
cytidine/uridine monophosphate kinase 1
affects expression
EXP
Benzbromarone affects the expression of CMPK1 mRNA
CTD
PMID:19483382
NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
G
Copg1
COPI coat complex subunit gamma 1
affects expression
EXP
Benzbromarone affects the expression of COPG1 mRNA
CTD
PMID:19483382
NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
G
Cops4
COP9 signalosome subunit 4
affects expression
EXP
Benzbromarone affects the expression of COPS4 mRNA
CTD
PMID:19483382
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
G
Coq3
coenzyme Q3 methyltransferase
affects expression
EXP
Benzbromarone affects the expression of COQ3 mRNA
CTD
PMID:19483382
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
G
Cox4i1
cytochrome c oxidase subunit 4i1
affects expression
EXP
Benzbromarone affects the expression of COX4I1 mRNA
CTD
PMID:19483382
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
G
Cpn1
carboxypeptidase N subunit 1
affects expression
EXP
Benzbromarone affects the expression of CPN1 mRNA
CTD
PMID:19483382
NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
G
Cpq
carboxypeptidase Q
affects expression
EXP
Benzbromarone affects the expression of CPQ mRNA
CTD
PMID:19483382
NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
G
Cpt1a
carnitine palmitoyltransferase 1A
increases expression
ISO
Benzbromarone results in increased expression of CPT1A mRNA; Benzbromarone results in increased expression of CPT1A protein
CTD
PMID:25108121
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Crem
cAMP responsive element modulator
affects expression
EXP
Benzbromarone affects the expression of CREM mRNA
CTD
PMID:19483382
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
G
Crp
C-reactive protein
multiple interactions decreases expression
ISO
Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein] Benzbromarone results in decreased expression of CRP protein
CTD
PMID:21329621
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
G
Csnk2b
casein kinase 2 beta
affects expression
EXP
Benzbromarone affects the expression of CSNK2B mRNA
CTD
PMID:19483382
NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
G
Csrp1
cysteine and glycine-rich protein 1
affects expression
EXP
Benzbromarone affects the expression of CSRP1 mRNA
CTD
PMID:19483382
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
G
Ctnna1
catenin alpha 1
affects expression
EXP
Benzbromarone affects the expression of CTNNA1 mRNA
CTD
PMID:19483382
NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
decreases activity
ISO
Benzbromarone results in decreased activity of CYP1A1 protein
CTD
PMID:33814510
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases activity
ISO
Benzbromarone results in decreased activity of CYP1B1 protein
CTD
PMID:33814510
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
G
Cyp2a1
cytochrome P450, family 2, subfamily a, polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP2A1 mRNA
CTD
PMID:19483382
NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
affects expression
EXP
Benzbromarone affects the expression of CYP2B2 mRNA
CTD
PMID:19483382
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
affects expression
EXP
Benzbromarone affects the expression of CYP2B3 mRNA
CTD
PMID:19483382
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
multiple interactions
ISO
Benzbromarone analog binds to and results in decreased activity of CYP2C19 protein; Benzbromarone binds to and results in decreased activity of CYP2C19 protein
CTD
PMID:15615526
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp2d3
cytochrome P450, family 2, subfamily d, polypeptide 3
affects expression
EXP
Benzbromarone affects the expression of CYP2D3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2D4 mRNA
CTD
PMID:19483382
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2F4 mRNA
CTD
PMID:19483382
NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2J4 mRNA
CTD
PMID:19483382
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
G
Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP2T1 mRNA
CTD
PMID:19483382
NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
G
Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP3A23-3A1 mRNA
CTD
PMID:19483382
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
G
Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
affects expression
EXP
Benzbromarone affects the expression of CYP3A9 mRNA
CTD
PMID:19483382
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
G
Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
affects expression
EXP
Benzbromarone affects the expression of CYP4A8 mRNA
CTD
PMID:19483382
NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
G
Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
affects expression
EXP
Benzbromarone affects the expression of CYP4F6 mRNA
CTD
PMID:19483382
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
G
Dbi
diazepam binding inhibitor
affects expression
EXP
Benzbromarone affects the expression of DBI mRNA
CTD
PMID:19483382
NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
G
Dcaf11
DDB1 and CUL4 associated factor 11
affects expression
EXP
Benzbromarone affects the expression of DCAF11 mRNA
CTD
PMID:19483382
NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
G
Dcxr
dicarbonyl and L-xylulose reductase
affects expression
EXP
Benzbromarone affects the expression of DCXR mRNA
CTD
PMID:19483382
NCBI chr10:106,006,404...106,008,293
G
Decr1
2,4-dienoyl-CoA reductase 1
affects expression
EXP
Benzbromarone affects the expression of DECR1 mRNA
CTD
PMID:19483382
NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
G
Dexi
Dexi homolog
affects expression
EXP
Benzbromarone affects the expression of DEXI mRNA
CTD
PMID:19483382
NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
G
Dgat1
diacylglycerol O-acyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of DGAT1 mRNA
CTD
PMID:19483382
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
G
Dhcr24
24-dehydrocholesterol reductase
affects expression
EXP
Benzbromarone affects the expression of DHCR24 mRNA
CTD
PMID:19483382
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
G
Dhrs4
dehydrogenase/reductase 4
affects expression
EXP
Benzbromarone affects the expression of DHRS4 mRNA
CTD
PMID:19483382
NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
G
Dhrs7b
dehydrogenase/reductase 7B
affects expression
EXP
Benzbromarone affects the expression of DHRS7B mRNA
CTD
PMID:19483382
NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
G
Dhx16
DEAH-box helicase 16
affects expression
EXP
Benzbromarone affects the expression of DHX16 mRNA
CTD
PMID:19483382
NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
G
Dmac2l
distal membrane arm assembly component 2 like
affects expression
EXP
Benzbromarone affects the expression of DMAC2L mRNA
CTD
PMID:19483382
NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
G
Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
affects expression
EXP
Benzbromarone affects the expression of DNAJC3 mRNA
CTD
PMID:19483382
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
G
Dpp4
dipeptidylpeptidase 4
affects expression
EXP
Benzbromarone affects the expression of DPP4 mRNA
CTD
PMID:19483382
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpyd
dihydropyrimidine dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of DPYD mRNA
CTD
PMID:19483382
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
G
Ears2
glutamyl-tRNA synthetase 2, mitochondrial
affects expression
EXP
Benzbromarone affects the expression of EARS2 mRNA
CTD
PMID:19483382
NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
G
Echs1
enoyl-CoA hydratase, short chain 1
affects expression
EXP
Benzbromarone affects the expression of ECHS1 mRNA
CTD
PMID:19483382
NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
G
Eci1
enoyl-CoA delta isomerase 1
affects expression
EXP
Benzbromarone affects the expression of ECI1 mRNA
CTD
PMID:19483382
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
G
Eci2
enoyl-CoA delta isomerase 2
affects expression
EXP
Benzbromarone affects the expression of ECI2 mRNA
CTD
PMID:19483382
NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
G
Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
EXP
Benzbromarone affects the expression of EEF1G mRNA
CTD
PMID:19483382
NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of EHHADH mRNA
CTD
PMID:19483382
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
G
Eif4a2
eukaryotic translation initiation factor 4A2
affects expression
EXP
Benzbromarone affects the expression of EIF4A2 mRNA
CTD
PMID:19483382
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
affects expression
EXP
Benzbromarone affects the expression of EIF4EBP1 mRNA
CTD
PMID:19483382
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
G
Eif4h
eukaryotic translation initiation factor 4H
affects expression
EXP
Benzbromarone affects the expression of EIF4H mRNA
CTD
PMID:19483382
NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
G
Enc1
ectodermal-neural cortex 1
affects expression
EXP
Benzbromarone affects the expression of ENC1 mRNA
CTD
PMID:19483382
NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
G
Eno1
enolase 1
affects expression
EXP
Benzbromarone affects the expression of ENO1 mRNA
CTD
PMID:19483382
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
G
Enpep
glutamyl aminopeptidase
affects expression
EXP
Benzbromarone affects the expression of ENPEP mRNA
CTD
PMID:19483382
NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
G
Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
affects expression
EXP
Benzbromarone affects the expression of ENPP1 mRNA
CTD
PMID:19483382
NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
G
Epcam
epithelial cell adhesion molecule
affects expression
EXP
Benzbromarone affects the expression of EPCAM mRNA
CTD
PMID:19483382
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
G
Erp29
endoplasmic reticulum protein 29
affects expression
EXP
Benzbromarone affects the expression of ERP29 mRNA
CTD
PMID:19483382
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
G
Esd
esterase D
affects expression
EXP
Benzbromarone affects the expression of ESD mRNA
CTD
PMID:19483382
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
G
Etfb
electron transfer flavoprotein subunit beta
affects expression
EXP
Benzbromarone affects the expression of ETFB mRNA
CTD
PMID:19483382
NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
G
Eya2
EYA transcriptional coactivator and phosphatase 2
decreases activity
ISO
Benzbromarone results in decreased activity of EYA2 protein
CTD
PMID:22545090
NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
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Eya3
EYA transcriptional coactivator and phosphatase 3
decreases activity
ISO
Benzbromarone results in decreased activity of EYA3 protein
CTD
PMID:22545090
NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518
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Faah
fatty acid amide hydrolase
affects expression
EXP
Benzbromarone affects the expression of FAAH mRNA
CTD
PMID:19483382
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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Fabp4
fatty acid binding protein 4
increases expression
ISO
Benzbromarone results in increased expression of FABP4 mRNA
CTD
PMID:19048458
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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Fads2
fatty acid desaturase 2
affects expression
EXP
Benzbromarone affects the expression of FADS2 mRNA
CTD
PMID:19483382
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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Fbp1
fructose-bisphosphatase 1
affects expression
EXP
Benzbromarone affects the expression of FBP1 mRNA
CTD
PMID:19483382
NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
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Fdft1
farnesyl diphosphate farnesyl transferase 1
affects expression
EXP
Benzbromarone affects the expression of FDFT1 mRNA
CTD
PMID:19483382
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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Fdps
farnesyl diphosphate synthase
affects expression
EXP
Benzbromarone affects the expression of FDPS mRNA
CTD
PMID:19483382
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Fdx2
ferredoxin 2
affects expression
EXP
Benzbromarone affects the expression of FDX2 mRNA
CTD
PMID:19483382
NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849
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Fmo1
flavin containing dimethylaniline monoxygenase 1
affects expression
EXP
Benzbromarone affects the expression of FMO1 mRNA
CTD
PMID:19483382
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
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Gamt
guanidinoacetate N-methyltransferase
affects expression
EXP
Benzbromarone affects the expression of GAMT mRNA
CTD
PMID:19483382
NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of GAPDH mRNA
CTD
PMID:19483382
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Gbe1
1,4-alpha-glucan branching enzyme 1
affects expression
EXP
Benzbromarone affects the expression of GBE1 mRNA
CTD
PMID:19483382
NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
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Gchfr
GTP cyclohydrolase I feedback regulator
affects expression
EXP
Benzbromarone affects the expression of GCHFR mRNA
CTD
PMID:19483382
NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
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Ggh
gamma-glutamyl hydrolase
affects expression
EXP
Benzbromarone affects the expression of GGH mRNA
CTD
PMID:19483382
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
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Gjb1
gap junction protein, beta 1
affects expression
EXP
Benzbromarone affects the expression of GJB1 mRNA
CTD
PMID:19483382
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
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Gpld1
glycosylphosphatidylinositol specific phospholipase D1
affects expression
EXP
Benzbromarone affects the expression of GPLD1 mRNA
CTD
PMID:19483382
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
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Gpx1
glutathione peroxidase 1
affects expression
EXP
Benzbromarone affects the expression of GPX1 mRNA
CTD
PMID:19483382
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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Gpx4
glutathione peroxidase 4
affects expression
EXP
Benzbromarone affects the expression of GPX4 mRNA
CTD
PMID:19483382
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
affects expression
EXP
Benzbromarone affects the expression of GRINA mRNA
CTD
PMID:19483382
NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
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Grpel1
GrpE-like 1, mitochondrial
affects expression
EXP
Benzbromarone affects the expression of GRPEL1 mRNA
CTD
PMID:19483382
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
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Gstt1
glutathione S-transferase theta 1
affects expression
EXP
Benzbromarone affects the expression of GSTT1 mRNA
CTD
PMID:19483382
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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Gtf2h5
general transcription factor IIH subunit 5
affects expression
EXP
Benzbromarone affects the expression of GTF2H5 mRNA
CTD
PMID:19483382
NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
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Gzma
granzyme A
affects expression
EXP
Benzbromarone affects the expression of GZMA mRNA
CTD
PMID:19483382
NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
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H3f3b
H3.3 histone B
affects expression
EXP
Benzbromarone affects the expression of H3F3B mRNA
CTD
PMID:19483382
NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709
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Hal
histidine ammonia lyase
affects expression
EXP
Benzbromarone affects the expression of HAL mRNA
CTD
PMID:19483382
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
G
Hao2
hydroxyacid oxidase 2
affects expression
EXP
Benzbromarone affects the expression of HAO2 mRNA
CTD
PMID:19483382
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
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Hba-a2
hemoglobin alpha, adult chain 2
affects expression
EXP
Benzbromarone affects the expression of HBA-A2 mRNA
CTD
PMID:19483382
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
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Hbb
hemoglobin subunit beta
affects expression
EXP
Benzbromarone affects the expression of HBB mRNA
CTD
PMID:19483382
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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Hdc
histidine decarboxylase
affects expression
EXP
Benzbromarone affects the expression of HDC mRNA
CTD
PMID:19483382
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
G
Hgd
homogentisate 1, 2-dioxygenase
affects expression
EXP
Benzbromarone affects the expression of HGD mRNA
CTD
PMID:19483382
NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
G
Hmgn1
high mobility group nucleosome binding domain 1
affects expression
EXP
Benzbromarone affects the expression of HMGN1 mRNA
CTD
PMID:19483382
NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of HPRT1 mRNA
CTD
PMID:19483382
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hps5
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
affects expression
EXP
Benzbromarone affects the expression of HPS5 mRNA
CTD
PMID:19483382
NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects expression
EXP
Benzbromarone affects the expression of HSD17B4 mRNA
CTD
PMID:19483382
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
G
Hsdl2
hydroxysteroid dehydrogenase like 2
affects expression
EXP
Benzbromarone affects the expression of HSDL2 mRNA
CTD
PMID:19483382
NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
G
Htra1
HtrA serine peptidase 1
affects expression
EXP
Benzbromarone affects the expression of HTRA1 mRNA
CTD
PMID:19483382
NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
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Igf1
insulin-like growth factor 1
affects expression
EXP
Benzbromarone affects the expression of IGF1 mRNA
CTD
PMID:19483382
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igfals
insulin-like growth factor binding protein, acid labile subunit
affects expression
EXP
Benzbromarone affects the expression of IGFALS mRNA
CTD
PMID:19483382
NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
G
Igfbp2
insulin-like growth factor binding protein 2
affects expression
EXP
Benzbromarone affects the expression of IGFBP2 mRNA
CTD
PMID:19483382
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
G
Il1a
interleukin 1 alpha
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
multiple interactions
ISO
Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein]
CTD
PMID:21329621
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Impa1
inositol monophosphatase 1
affects expression
EXP
Benzbromarone affects the expression of IMPA1 mRNA
CTD
PMID:19483382
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
G
Inhbe
inhibin subunit beta E
affects expression
EXP
Benzbromarone affects the expression of INHBE mRNA
CTD
PMID:19483382
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
G
Isyna1
inositol-3-phosphate synthase 1
affects expression
EXP
Benzbromarone affects the expression of ISYNA1 mRNA
CTD
PMID:19483382
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
G
Itih4
inter-alpha-trypsin inhibitor heavy chain 4
affects expression
EXP
Benzbromarone affects the expression of ITIH4 mRNA
CTD
PMID:19483382
NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
G
Iyd
iodotyrosine deiodinase
decreases activity
ISO
Benzbromarone results in decreased activity of IYD protein
CTD
PMID:24012475
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
G
Jak1
Janus kinase 1
affects expression
EXP
Benzbromarone affects the expression of JAK1 mRNA
CTD
PMID:19483382
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
G
Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
affects expression
EXP
Benzbromarone affects the expression of KDELR2 mRNA
CTD
PMID:19483382
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
G
Kdr
kinase insert domain receptor
affects expression
EXP
Benzbromarone affects the expression of KDR mRNA
CTD
PMID:19483382
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
G
Krt8
keratin 8
affects expression
EXP
Benzbromarone affects the expression of KRT8 mRNA
CTD
PMID:19483382
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
G
Lcat
lecithin cholesterol acyltransferase
affects expression
EXP
Benzbromarone affects the expression of LCAT mRNA
CTD
PMID:19483382
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
G
Lcmt1
leucine carboxyl methyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of LCMT1 mRNA
CTD
PMID:19483382
NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
G
Lipc
lipase C, hepatic type
affects expression
EXP
Benzbromarone affects the expression of LIPC mRNA
CTD
PMID:19483382
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
G
Lox
lysyl oxidase
affects expression
EXP
Benzbromarone affects the expression of LOX mRNA
CTD
PMID:19483382
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Lpl
lipoprotein lipase
increases expression
ISO
Benzbromarone results in increased expression of LPL protein
CTD
PMID:18274627
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
G
Lrp3
LDL receptor related protein 3
affects expression
EXP
Benzbromarone affects the expression of LRP3 mRNA
CTD
PMID:19483382
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
G
Man2b1
mannosidase, alpha, class 2B, member 1
affects expression
EXP
Benzbromarone affects the expression of MAN2B1 mRNA
CTD
PMID:19483382
NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
G
Map2k2
mitogen activated protein kinase kinase 2
affects expression
EXP
Benzbromarone affects the expression of MAP2K2 mRNA
CTD
PMID:19483382
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Masp2
MBL associated serine protease 2
affects expression
EXP
Benzbromarone affects the expression of MASP2 mRNA
CTD
PMID:19483382
NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
G
Me1
malic enzyme 1
affects expression
EXP
Benzbromarone affects the expression of ME1 mRNA
CTD
PMID:19483382
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
G
Mmut
methylmalonyl-CoA mutase
affects expression
EXP
Benzbromarone affects the expression of MMUT mRNA
CTD
PMID:19483382
NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
G
Mro
maestro
affects expression
EXP
Benzbromarone affects the expression of MRO mRNA
CTD
PMID:19483382
NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044
G
Mrpl2
mitochondrial ribosomal protein L2
affects expression
EXP
Benzbromarone affects the expression of MRPL2 mRNA
CTD
PMID:19483382
NCBI chr 9:14,333,233...14,337,006
Ensembl chr 9:14,333,234...14,337,040
G
mrpl9
mitochondrial ribosomal protein L9
affects expression
EXP
Benzbromarone affects the expression of MRPL9 mRNA
CTD
PMID:19483382
NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095
G
Mug2
murinoglobulin 2
affects expression
EXP
Benzbromarone affects the expression of PZP mRNA
CTD
PMID:19483382
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
G
Myadm
myeloid-associated differentiation marker
affects expression
EXP
Benzbromarone affects the expression of MYADM mRNA
CTD
PMID:19483382
NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
G
Mycbp2
MYC binding protein 2
affects expression
EXP
Benzbromarone affects the expression of MYCBP2 mRNA
CTD
PMID:19483382
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
G
Myo1d
myosin ID
affects expression
EXP
Benzbromarone affects the expression of MYO1D mRNA
CTD
PMID:19483382
NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
G
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
affects expression
EXP
Benzbromarone affects the expression of NAA38 mRNA
CTD
PMID:19483382
NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494
G
Nap1l1
nucleosome assembly protein 1-like 1
affects expression
EXP
Benzbromarone affects the expression of NAP1L1 mRNA
CTD
PMID:19483382
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
G
Nat8
N-acetyltransferase 8
affects expression
EXP
Benzbromarone affects the expression of NAT8 mRNA
CTD
PMID:19483382
NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
G
Ndrg2
NDRG family member 2
affects expression
EXP
Benzbromarone affects the expression of NDRG2 mRNA
CTD
PMID:19483382
NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
G
Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
affects expression
EXP
Benzbromarone affects the expression of NDUFS5 mRNA
CTD
PMID:19483382
NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603 Ensembl chr14:135,974,034...135,979,603 Ensembl chr 2:135,974,034...135,979,603
G
Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
affects expression
EXP
Benzbromarone affects the expression of NDUFV3 mRNA
CTD
PMID:19483382
NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074 Ensembl chr13:9,612,431...9,623,074
G
Neu2
neuraminidase 2
affects expression
EXP
Benzbromarone affects the expression of NEU2 mRNA
CTD
PMID:19483382
NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
G
Nfx1
nuclear transcription factor, X-box binding 1
affects expression
EXP
Benzbromarone affects the expression of NFX1 mRNA
CTD
PMID:19483382
NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
G
Nipal2
NIPA-like domain containing 2
affects expression
EXP
Benzbromarone affects the expression of NIPAL2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:65,774,477...65,884,807
G
Nit1
nitrilase 1
affects expression
EXP
Benzbromarone affects the expression of NIT1 mRNA
CTD
PMID:19483382
NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
Benzbromarone affects the expression of NME2 mRNA
CTD
PMID:19483382
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects expression
EXP
Benzbromarone affects the expression of NR1I3 mRNA
CTD
PMID:19483382
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
EXP
Benzbromarone affects the expression of NR3C1 mRNA
CTD
PMID:19483382
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Oaf
out at first homolog
affects expression
EXP
Benzbromarone affects the expression of OAF mRNA
CTD
PMID:19483382
NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
G
Obp3
alpha-2u globulin PGCL4
affects expression
EXP
Benzbromarone affects the expression of OBP3 mRNA
CTD
PMID:19483382
NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
G
Ogdh
oxoglutarate dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of OGDH mRNA
CTD
PMID:19483382
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
G
Olr59
olfactory receptor 59
affects expression
EXP
Benzbromarone affects the expression of OLR59 mRNA
CTD
PMID:19483382
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
G
Ostc
oligosaccharyltransferase complex non-catalytic subunit
affects expression
EXP
Benzbromarone affects the expression of OSTC mRNA
CTD
PMID:19483382
NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
G
Otc
ornithine transcarbamylase
affects expression
EXP
Benzbromarone affects the expression of OTC mRNA
CTD
PMID:19483382
NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
G
Pabpc4
poly(A) binding protein, cytoplasmic 4
affects expression
EXP
Benzbromarone affects the expression of PABPC4 mRNA
CTD
PMID:19483382
NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
G
Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
affects expression
EXP
Benzbromarone affects the expression of PAICS mRNA
CTD
PMID:19483382
NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
G
Pc
pyruvate carboxylase
affects expression
EXP
Benzbromarone affects the expression of PCX mRNA
CTD
PMID:19483382
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
G
Pccb
propionyl-CoA carboxylase subunit beta
affects expression
EXP
Benzbromarone affects the expression of PCCB mRNA
CTD
PMID:19483382
NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234
G
Pcsk6
proprotein convertase subtilisin/kexin type 6
affects expression
EXP
Benzbromarone affects the expression of PCSK6 mRNA
CTD
PMID:19483382
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
G
Pctp
phosphatidylcholine transfer protein
affects expression
EXP
Benzbromarone affects the expression of PCTP mRNA
CTD
PMID:19483382
NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
G
Pdcl3
phosducin-like 3
affects expression
EXP
Benzbromarone affects the expression of PDCL3 mRNA
CTD
PMID:19483382
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
G
Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
Benzbromarone affects the expression of PDIA3 mRNA
CTD
PMID:19483382
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
G
Pdia6
protein disulfide isomerase family A, member 6
affects expression
EXP
Benzbromarone affects the expression of PDIA6 mRNA
CTD
PMID:19483382
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
G
Pex19
peroxisomal biogenesis factor 19
affects expression
EXP
Benzbromarone affects the expression of PEX19 mRNA
CTD
PMID:19483382
NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
G
Pgam1
phosphoglycerate mutase 1
affects expression
EXP
Benzbromarone affects the expression of PGAM1 mRNA
CTD
PMID:19483382
NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
G
Pgrmc1
progesterone receptor membrane component 1
affects expression
EXP
Benzbromarone affects the expression of PGRMC1 mRNA
CTD
PMID:19483382
NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682
G
Phyh
phytanoyl-CoA 2-hydroxylase
affects expression
EXP
Benzbromarone affects the expression of PHYH mRNA
CTD
PMID:19483382
NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
G
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
affects expression
EXP
Benzbromarone affects the expression of PIGP mRNA
CTD
PMID:19483382
NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321
G
Pklr
pyruvate kinase L/R
affects expression
EXP
Benzbromarone affects the expression of PKLR mRNA
CTD
PMID:19483382
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
G
Plbd1
phospholipase B domain containing 1
affects expression
EXP
Benzbromarone affects the expression of PLBD1 mRNA
CTD
PMID:19483382
NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
G
Plg
plasminogen
affects expression
EXP
Benzbromarone affects the expression of PLG mRNA
CTD
PMID:19483382
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
G
Pls3
plastin 3
affects expression
EXP
Benzbromarone affects the expression of PLS3 mRNA
CTD
PMID:19483382
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
G
Pon2
paraoxonase 2
affects expression
EXP
Benzbromarone affects the expression of PON2 mRNA
CTD
PMID:19483382
NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
G
Pparg
peroxisome proliferator-activated receptor gamma
affects expression
ISO
Benzbromarone affects the expression of PPARG mRNA
CTD
PMID:19048458
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
affects expression
EXP
Benzbromarone affects the expression of PPDPF mRNA
CTD
PMID:19483382
NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036
G
Prdx2
peroxiredoxin 2
affects expression
EXP
Benzbromarone affects the expression of PRDX2 mRNA
CTD
PMID:19483382
NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
G
Prdx6
peroxiredoxin 6
affects expression
EXP
Benzbromarone affects the expression of PRDX6 mRNA
CTD
PMID:19483382
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
G
Proc
protein C, inactivator of coagulation factors Va and VIIIa
affects expression
EXP
Benzbromarone affects the expression of PROC mRNA
CTD
PMID:19483382
NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
G
Prpsap1
phosphoribosyl pyrophosphate synthetase-associated protein 1
affects expression
EXP
Benzbromarone affects the expression of PRPSAP1 mRNA
CTD
PMID:19483382
NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
G
Psma6
proteasome 20S subunit alpha 6
affects expression
EXP
Benzbromarone affects the expression of PSMA6 mRNA
CTD
PMID:19483382
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
G
Psmb1
proteasome 20S subunit beta 1
affects expression
EXP
Benzbromarone affects the expression of PSMB1 mRNA
CTD
PMID:19483382
NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
G
Psmb3
proteasome 20S subunit beta 3
affects expression
EXP
Benzbromarone affects the expression of PSMB3 mRNA
CTD
PMID:19483382
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
G
Psmc1
proteasome 26S subunit, ATPase 1
affects expression
EXP
Benzbromarone affects the expression of PSMC1 mRNA
CTD
PMID:19483382
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
G
Psmc3
proteasome 26S subunit, ATPase 3
affects expression
EXP
Benzbromarone affects the expression of PSMC3 mRNA
CTD
PMID:19483382
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
G
Psmc5
proteasome 26S subunit, ATPase 5
affects expression
EXP
Benzbromarone affects the expression of PSMC5 mRNA
CTD
PMID:19483382
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
G
Psmd1
proteasome 26S subunit, non-ATPase 1
affects expression
EXP
Benzbromarone affects the expression of PSMD1 mRNA
CTD
PMID:19483382
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
G
Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
affects expression
EXP
Benzbromarone affects the expression of PSMD4 mRNA
CTD
PMID:19483382
NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
G
Ptms
parathymosin
affects expression
EXP
Benzbromarone affects the expression of PTMS mRNA
CTD
PMID:19483382
NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Benzbromarone affects the expression of PTPRF mRNA
CTD
PMID:19483382
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
G
Pttg1ip
PTTG1 interacting protein
affects expression
EXP
Benzbromarone affects the expression of PTTG1IP mRNA
CTD
PMID:19483382
NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
G
Pygl
glycogen phosphorylase L
affects expression
EXP
Benzbromarone affects the expression of PYGL mRNA
CTD
PMID:19483382
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
G
Rab5if
RAB5 interacting factor
affects expression
EXP
Benzbromarone affects the expression of RAB5IF mRNA
CTD
PMID:19483382
NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012
G
Rida
reactive intermediate imine deaminase A homolog
affects expression
EXP
Benzbromarone affects the expression of RIDA mRNA
CTD
PMID:19483382
NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
G
Rnase4
ribonuclease A family member 4
affects expression
EXP
Benzbromarone affects the expression of RNASE4 mRNA
CTD
PMID:19483382
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
G
Rnf103
ring finger protein 103
affects expression
EXP
Benzbromarone affects the expression of RNF103 mRNA
CTD
PMID:19483382
NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919
G
Rnps1
RNA binding protein with serine rich domain 1
affects expression
EXP
Benzbromarone affects the expression of RNPS1 mRNA
CTD
PMID:19483382
NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858
G
Rpl11
ribosomal protein L11
affects expression
EXP
Benzbromarone affects the expression of RPL11 mRNA
CTD
PMID:19483382
NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
G
Rpl13
ribosomal protein L13
affects expression
EXP
Benzbromarone affects the expression of RPL13 mRNA
CTD
PMID:19483382
NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
G
Rpl15
ribosomal protein L15
affects expression
EXP
Benzbromarone affects the expression of RPL15 mRNA
CTD
PMID:19483382
NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
G
Rpl17
ribosomal protein L17
affects expression
EXP
Benzbromarone affects the expression of RPL17 mRNA
CTD
PMID:19483382
NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
G
Rpl23
ribosomal protein L23
affects expression
EXP
Benzbromarone affects the expression of RPL23 mRNA
CTD
PMID:19483382
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
G
Rpl3
ribosomal protein L3
affects expression
EXP
Benzbromarone affects the expression of RPL3 mRNA
CTD
PMID:19483382
NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
G
Rpl32
ribosomal protein L32
affects expression
EXP
Benzbromarone affects the expression of RPL32 mRNA
CTD
PMID:19483382
NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
G
Rpl4
ribosomal protein L4
affects expression
EXP
Benzbromarone affects the expression of RPL4 mRNA
CTD
PMID:19483382
NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
G
Rpn2
ribophorin II
affects expression
EXP
Benzbromarone affects the expression of RPN2 mRNA
CTD
PMID:19483382
NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
G
Rps14
ribosomal protein S14
affects expression
EXP
Benzbromarone affects the expression of RPS14 mRNA
CTD
PMID:19483382
NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
G
Rps18
ribosomal protein S18
affects expression
EXP
Benzbromarone affects the expression of RPS18 mRNA
CTD
PMID:19483382
NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146 Ensembl chr20:101,204,500...101,205,146
G
Rps19
ribosomal protein S19
affects expression
EXP
Benzbromarone affects the expression of RPS19 mRNA
CTD
PMID:19483382
NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
G
Rps20
ribosomal protein S20
affects expression
EXP
Benzbromarone affects the expression of RPS20 mRNA
CTD
PMID:19483382
NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475 Ensembl chr 9:16,819,304...16,820,475 Ensembl chr 3:16,819,304...16,820,475
G
Rps3a
ribosomal protein S3a
affects expression
EXP
Benzbromarone affects the expression of RPS3A mRNA
CTD
PMID:19483382
NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
G
Rps6
ribosomal protein S6
affects expression
EXP
Benzbromarone affects the expression of RPS6 mRNA
CTD
PMID:19483382
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
G
Rps8
ribosomal protein S8
affects expression
EXP
Benzbromarone affects the expression of RPS8 mRNA
CTD
PMID:19483382
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
G
Rras2
RAS related 2
affects expression
EXP
Benzbromarone affects the expression of RRAS2 mRNA
CTD
PMID:19483382
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
G
RT1-S3
RT1 class Ib, locus S3
affects expression
EXP
Benzbromarone affects the expression of RT1-S3 mRNA
CTD
PMID:19483382
NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
G
S1pr1
sphingosine-1-phosphate receptor 1
affects expression
EXP
Benzbromarone affects the expression of S1PR1 mRNA
CTD
PMID:19483382
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
G
Sbspon
somatomedin B and thrombospondin, type 1 domain containing
affects expression
EXP
Benzbromarone affects the expression of SBSPON mRNA
CTD
PMID:19483382
NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420
G
Sdc2
syndecan 2
affects expression
EXP
Benzbromarone affects the expression of SDC2 mRNA
CTD
PMID:19483382
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
G
Sdhc
succinate dehydrogenase complex subunit C
affects expression
EXP
Benzbromarone affects the expression of SDHC mRNA
CTD
PMID:19483382
NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253
G
Sdhd
succinate dehydrogenase complex subunit D
affects expression
EXP
Benzbromarone affects the expression of SDHD mRNA
CTD
PMID:19483382
NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238
G
Serinc3
serine incorporator 3
affects expression
EXP
Benzbromarone affects the expression of SERINC3 mRNA
CTD
PMID:19483382
NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
G
Serpina1
serpin family A member 1
affects expression
EXP
Benzbromarone affects the expression of SERPINA1 mRNA
CTD
PMID:19483382
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
G
Serpina10
serpin family A member 10
affects expression
EXP
Benzbromarone affects the expression of SERPINA10 mRNA
CTD
PMID:19483382
NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544
G
Serpina4
serpin family A member 4
affects expression
EXP
Benzbromarone affects the expression of SERPINA4 mRNA
CTD
PMID:19483382
NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082
G
Serpinf2
serpin family F member 2
affects expression
EXP
Benzbromarone affects the expression of SERPINF2 mRNA
CTD
PMID:19483382
NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
G
Sfxn1
sideroflexin 1
affects expression
EXP
Benzbromarone affects the expression of SFXN1 mRNA
CTD
PMID:19483382
NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
G
Shmt2
serine hydroxymethyltransferase 2
affects expression
EXP
Benzbromarone affects the expression of SHMT2 mRNA
CTD
PMID:19483382
NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
G
Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC22A1 mRNA
CTD
PMID:19483382
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
G
Slc22a12
solute carrier family 22 member 12
affects activity decreases activity multiple interactions affects response to substance
ISO EXP
Benzbromarone affects the activity of SLC22A12 protein Benzbromarone results in decreased activity of SLC22A12 protein Benzbromarone inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid] SLC22A12 protein affects the susceptibility to Benzbromarone Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Oxypurinol]; Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
CTD
PMID:14694169 PMID:14747372 PMID:16135657 PMID:18670416 PMID:20486468 PMID:21074513 PMID:21272127 PMID:21449597 More...
NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
G
Slc22a6
solute carrier family 22 member 6
multiple interactions
ISO
Benzbromarone inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid]
CTD
PMID:12472777
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
G
Slc23a1
solute carrier family 23 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC23A1 mRNA
CTD
PMID:19483382
NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
G
Slc25a13
solute carrier family 25 member 13
affects expression
EXP
Benzbromarone affects the expression of SLC25A13 mRNA
CTD
PMID:19483382
NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902
G
Slc25a3
solute carrier family 25 member 3
affects expression
EXP
Benzbromarone affects the expression of SLC25A3 mRNA
CTD
PMID:19483382
NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
G
Slc27a2
solute carrier family 27 member 2
affects expression
EXP
Benzbromarone affects the expression of SLC27A2 mRNA
CTD
PMID:19483382
NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
G
Slc2a9
solute carrier family 2 member 9
multiple interactions
ISO
Benzbromarone inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid] Benzbromarone inhibits the reaction [SLC2A9 protein alternative form results in increased transport of Uric Acid]
CTD
PMID:18842065 PMID:19587147
NCBI chr14:72,328,334...72,461,981
Ensembl chr14:72,328,320...72,461,981
G
Slc39a8
solute carrier family 39 member 8
affects expression
EXP
Benzbromarone affects the expression of SLC39A8 mRNA
CTD
PMID:19483382
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
G
Slc46a1
solute carrier family 46 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC46A1 mRNA
CTD
PMID:19483382
NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
G
Slc66a2
solute carrier family 66 member 2
affects expression
EXP
Benzbromarone affects the expression of SLC66A2 mRNA
CTD
PMID:19483382
NCBI chr18:73,702,472...73,739,678
Ensembl chr18:73,702,564...73,739,676
G
Slc6a6
solute carrier family 6 member 6
affects expression
EXP
Benzbromarone affects the expression of SLC6A6 mRNA
CTD
PMID:19483382
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
G
Sod2
superoxide dismutase 2
increases expression
ISO
Benzbromarone results in increased expression of SOD2 mRNA
CTD
PMID:25108121
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Sppl2a
signal peptide peptidase-like 2A
affects expression
EXP
Benzbromarone affects the expression of SPPL2A mRNA
CTD
PMID:19483382
NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:114,151,069...114,193,264
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Srm
spermidine synthase
affects expression
EXP
Benzbromarone affects the expression of SRM mRNA
CTD
PMID:19483382
NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
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Srprb
SRP receptor subunit beta
affects expression
EXP
Benzbromarone affects the expression of SRPRB mRNA
CTD
PMID:19483382
NCBI chr 8:103,768,685...103,782,632
G
Ssx2ip
SSX family member 2 interacting protein
affects expression
EXP
Benzbromarone affects the expression of SSX2IP mRNA
CTD
PMID:19483382
NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
affects expression
EXP
Benzbromarone affects the expression of ST3GAL6 mRNA
CTD
PMID:19483382
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of ST6GAL1 mRNA
CTD
PMID:19483382
NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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Suclg1
succinate-CoA ligase GDP/ADP-forming subunit alpha
affects expression
EXP
Benzbromarone affects the expression of SUCLG1 mRNA
CTD
PMID:19483382
NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600
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Surf4
surfeit 4
affects expression
EXP
Benzbromarone affects the expression of SURF4 mRNA
CTD
PMID:19483382
NCBI chr 3:10,248,360...10,261,537
Ensembl chr 3:10,241,837...10,263,315
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Synj2bp
synaptojanin 2 binding protein
affects expression
EXP
Benzbromarone affects the expression of SYNJ2BP mRNA
CTD
PMID:19483382
NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
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Tgfbi
transforming growth factor, beta induced
affects expression
EXP
Benzbromarone affects the expression of TGFBI mRNA
CTD
PMID:19483382
NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
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Thnsl2
threonine synthase-like 2
affects expression
EXP
Benzbromarone affects the expression of THNSL2 mRNA
CTD
PMID:19483382
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
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Timm21
translocase of inner mitochondrial membrane 21
affects expression
EXP
Benzbromarone affects the expression of TIMM21 mRNA
CTD
PMID:19483382
NCBI chr18:78,314,900...78,319,362
Ensembl chr18:78,314,909...78,319,454
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Tkfc
triokinase and FMN cyclase
affects expression
EXP
Benzbromarone affects the expression of TKFC mRNA
CTD
PMID:19483382
NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
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Tmbim1
transmembrane BAX inhibitor motif containing 1
affects expression
EXP
Benzbromarone affects the expression of TMBIM1 mRNA
CTD
PMID:19483382
NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
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Tmco1
transmembrane and coiled-coil domains 1
affects expression
EXP
Benzbromarone affects the expression of TMCO1 mRNA
CTD
PMID:19483382
NCBI chr13:79,460,229...79,483,557
Ensembl chr13:79,460,135...79,483,555
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Tmed2
transmembrane p24 trafficking protein 2
affects expression
EXP
Benzbromarone affects the expression of TMED2 mRNA
CTD
PMID:19483382
NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
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Tmed7
transmembrane p24 trafficking protein 7
affects expression
EXP
Benzbromarone affects the expression of TMED7 mRNA
CTD
PMID:19483382
NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
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Tmem123
transmembrane protein 123
affects expression
EXP
Benzbromarone affects the expression of TMEM123 mRNA
CTD
PMID:19483382
NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224
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Tmem97
transmembrane protein 97
affects expression
EXP
Benzbromarone affects the expression of TMEM97 mRNA
CTD
PMID:19483382
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tnf
tumor necrosis factor
increases expression multiple interactions
ISO
Benzbromarone results in increased expression of TNF protein [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101 PMID:19933411
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Txn1
thioredoxin 1
affects expression
EXP
Benzbromarone affects the expression of TXN1 mRNA
CTD
PMID:19483382
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnl1
thioredoxin-like 1
affects expression
EXP
Benzbromarone affects the expression of TXNL1 mRNA
CTD
PMID:19483382
NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
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Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
affects expression
EXP
Benzbromarone affects the expression of UBA52 mRNA
CTD
PMID:19483382
NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
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Ube2n
ubiquitin-conjugating enzyme E2N
affects expression
EXP
Benzbromarone affects the expression of UBE2N mRNA
CTD
PMID:19483382
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
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Ufd1
ubiquitin recognition factor in ER associated degradation 1
affects expression
EXP
Benzbromarone affects the expression of UFD1 mRNA
CTD
PMID:19483382
NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
affects expression
EXP
Benzbromarone affects the expression of UGT1A1 mRNA
CTD
PMID:19483382
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
affects expression
EXP
Benzbromarone affects the expression of UQCR11 mRNA
CTD
PMID:19483382
NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750
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Vnn1
vanin 1
affects expression
EXP
Benzbromarone affects the expression of VNN1 mRNA
CTD
PMID:19483382
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Wdr26
WD repeat domain 26
affects expression
EXP
Benzbromarone affects the expression of WDR26 mRNA
CTD
PMID:19483382
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
affects expression
EXP
Benzbromarone affects the expression of YWHAG mRNA
CTD
PMID:19483382
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
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Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Benzbromarone affects the expression of ZDHHC23 mRNA
CTD
PMID:19483382
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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Zwint
ZW10 interacting kinetochore protein
affects expression
EXP
Benzbromarone affects the expression of ZWINT mRNA
CTD
PMID:19483382
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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Aacs
acetoacetyl-CoA synthetase
decreases expression
EXP
bromobenzene results in decreased expression of AACS mRNA
CTD
PMID:32479839
NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
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Aass
aminoadipate-semialdehyde synthase
increases expression
EXP
bromobenzene results in increased expression of AASS mRNA
CTD
PMID:32479839
NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
EXP
bromobenzene results in increased expression of ABCB1A mRNA
CTD
PMID:15976192
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb7
ATP binding cassette subfamily B member 7
increases expression
EXP
bromobenzene results in increased expression of ABCB7 mRNA
CTD
PMID:32479839
NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858
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Abcc3
ATP binding cassette subfamily C member 3
increases expression
EXP
bromobenzene results in increased expression of ABCC3 mRNA
CTD
PMID:17538237
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc4
ATP binding cassette subfamily C member 4
increases expression
EXP
bromobenzene results in increased expression of ABCC4 mRNA
CTD
PMID:32479839
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Abcc8
ATP binding cassette subfamily C member 8
decreases expression
EXP
bromobenzene results in decreased expression of ABCC8 mRNA
CTD
PMID:15976192
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
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Abcg2
ATP binding cassette subfamily G member 2
decreases expression
EXP
bromobenzene results in decreased expression of ABCG2 mRNA
CTD
PMID:32479839
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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Abhd15
abhydrolase domain containing 15
increases expression
EXP
bromobenzene results in increased expression of ABHD15 mRNA
CTD
PMID:32479839
NCBI chr10:62,363,209...62,368,600
Ensembl chr10:62,363,209...62,368,600
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Ablim3
actin binding LIM protein family, member 3
increases expression
EXP
bromobenzene results in increased expression of ABLIM3 mRNA
CTD
PMID:32479839
NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression
EXP
bromobenzene results in decreased expression of ACAT2 mRNA
CTD
PMID:32479839
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acer2
alkaline ceramidase 2
increases expression
EXP
bromobenzene results in increased expression of ACER2 mRNA
CTD
PMID:32479839
NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
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Ackr2
atypical chemokine receptor 2
increases expression
EXP
bromobenzene results in increased expression of ACKR2 mRNA
CTD
PMID:32479839
NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582
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Acly
ATP citrate lyase
decreases expression
EXP
bromobenzene results in decreased expression of ACLY mRNA
CTD
PMID:32479839
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Acot4
acyl-CoA thioesterase 4
increases expression
EXP
bromobenzene results in increased expression of ACOT4 mRNA
CTD
PMID:32479839
NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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Acsbg1
acyl-CoA synthetase bubblegum family member 1
increases expression
EXP
bromobenzene results in increased expression of ACSBG1 mRNA
CTD
PMID:32479839
NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
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Acsl1
acyl-CoA synthetase long-chain family member 1
decreases expression
EXP
bromobenzene results in decreased expression of ACSL1 mRNA
CTD
PMID:12628495
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsl3
acyl-CoA synthetase long-chain family member 3
decreases expression
EXP
bromobenzene results in decreased expression of ACSL3 mRNA
CTD
PMID:32479839
NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acss2
acyl-CoA synthetase short-chain family member 2
decreases expression
EXP
bromobenzene results in decreased expression of ACSS2 mRNA
CTD
PMID:32479839
NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Actb
actin, beta
increases expression
EXP
bromobenzene results in increased expression of ACTB mRNA
CTD
PMID:16036859
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Actl7b
actin-like 7b
decreases expression
EXP
bromobenzene results in decreased expression of ACTL7B mRNA
CTD
PMID:32479839
NCBI chr 5:71,445,532...71,446,920
Ensembl chr 5:71,445,534...71,446,920
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Actn4
actinin alpha 4
decreases expression
EXP
bromobenzene results in decreased expression of ACTN4 mRNA
CTD
PMID:15056800
NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
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Adamts15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
increases expression
EXP
bromobenzene results in increased expression of ADAMTS15 mRNA
CTD
PMID:32479839
NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249
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Adamts3
ADAM metallopeptidase with thrombospondin type 1, motif 3
increases expression
EXP
bromobenzene results in increased expression of ADAMTS3 mRNA
CTD
PMID:32479839
NCBI chr14:18,231,128...18,437,771
Ensembl chr14:18,231,165...18,435,556
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Adamts7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
decreases expression
EXP
bromobenzene results in decreased expression of ADAMTS7 mRNA
CTD
PMID:32479839
NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328
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Adgrf3
adhesion G protein-coupled receptor F3
increases expression
EXP
bromobenzene results in increased expression of ADGRF3 mRNA
CTD
PMID:32479839
NCBI chr 6:26,133,176...26,144,601
Ensembl chr 6:26,133,192...26,144,601
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Adgrg3
adhesion G protein-coupled receptor G3
decreases expression
EXP
bromobenzene results in decreased expression of ADGRG3 mRNA
CTD
PMID:32479839
NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123
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Adgrg5
adhesion G protein-coupled receptor G5
increases expression
EXP
bromobenzene results in increased expression of ADGRG5 mRNA
CTD
PMID:32479839
NCBI chr19:10,074,787...10,098,640
Ensembl chr19:10,079,375...10,097,214
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Adm2
adrenomedullin 2
increases expression
EXP
bromobenzene results in increased expression of ADM2 mRNA
CTD
PMID:32479839
NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
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Adora2b
adenosine A2B receptor
decreases expression
EXP
bromobenzene results in decreased expression of ADORA2B mRNA
CTD
PMID:32479839
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
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Adra2c
adrenoceptor alpha 2C
decreases expression
EXP
bromobenzene results in decreased expression of ADRA2C mRNA
CTD
PMID:32479839
NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846
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Ahr
aryl hydrocarbon receptor
increases expression
EXP
bromobenzene results in increased expression of AHR mRNA
CTD
PMID:32479839
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Aim2
absent in melanoma 2
decreases expression
EXP
bromobenzene results in decreased expression of AIM2 mRNA
CTD
PMID:32479839
NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
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Aip
aryl-hydrocarbon receptor-interacting protein
decreases expression
EXP
bromobenzene results in decreased expression of AIP mRNA
CTD
PMID:32479839
NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122
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Akr7a3
aldo-keto reductase family 7 member A3
increases expression
EXP
bromobenzene results in increased expression of AKR7A3 mRNA
CTD
PMID:12628495 PMID:15056800 PMID:32479839
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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Alad
aminolevulinate dehydratase
decreases activity multiple interactions decreases expression
ISO EXP
bromobenzene results in decreased activity of ALAD protein [Phenobarbital co-treated with bromobenzene] results in decreased activity of ALAD protein; Carbon Monoxide inhibits the reaction [[Phenobarbital co-treated with bromobenzene] results in decreased activity of ALAD protein] bromobenzene results in decreased expression of ALAD mRNA
CTD
PMID:6740708 PMID:16140629 PMID:32479839
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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Alb
albumin
increases expression affects binding
EXP
bromobenzene results in increased expression of ALB mRNA bromobenzene metabolite binds to ALB protein
CTD
PMID:12018992 PMID:17305373 PMID:23288050
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects binding increases expression
EXP
bromobenzene metabolite binds to ALDH1A1 protein bromobenzene results in increased expression of ALDH1A1 mRNA
CTD
PMID:12628495 PMID:17305373
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh2
aldehyde dehydrogenase 2 family member
affects binding
EXP
bromobenzene metabolite binds to ALDH2 protein
CTD
PMID:17305373
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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Aldh9a1
aldehyde dehydrogenase 9 family, member A1
affects binding
EXP
bromobenzene metabolite binds to ALDH9A1 protein
CTD
PMID:17305373
NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
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Alox15
arachidonate 15-lipoxygenase
increases expression
EXP
bromobenzene results in increased expression of ALOX15 mRNA
CTD
PMID:32479839
NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
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Als2cl
ALS2 C-terminal like
increases expression
EXP
bromobenzene results in increased expression of ALS2CL mRNA
CTD
PMID:32479839
NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
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Ambp
alpha-1-microglobulin/bikunin precursor
increases expression
EXP
bromobenzene results in increased expression of AMBP mRNA
CTD
PMID:23288050
NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
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Angptl1
angiopoietin-like 1
decreases expression
EXP
bromobenzene results in decreased expression of ANGPTL1 mRNA
CTD
PMID:32479839
NCBI chr13:68,963,186...68,981,649
Ensembl chr13:68,962,991...68,992,570
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Angptl4
angiopoietin-like 4
increases expression
EXP
bromobenzene results in increased expression of ANGPTL4 mRNA
CTD
PMID:32479839
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Angptl8
angiopoietin-like 8
decreases expression
EXP
bromobenzene results in decreased expression of ANGPTL8 mRNA
CTD
PMID:32479839
NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
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Ankle1
ankyrin repeat and LEM domain containing 1
increases expression
EXP
bromobenzene results in increased expression of ANKLE1 mRNA
CTD
PMID:32479839
NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729
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Ankmy1
ankyrin repeat and MYND domain containing 1
increases expression
EXP
bromobenzene results in increased expression of ANKMY1 mRNA
CTD
PMID:32479839
NCBI chr 9:93,423,664...93,476,651
Ensembl chr 9:93,423,963...93,477,236
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Ankrd1
ankyrin repeat domain 1
decreases expression
EXP
bromobenzene results in decreased expression of ANKRD1 mRNA
CTD
PMID:32479839
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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Ankrd13d
ankyrin repeat domain 13D
increases expression
EXP
bromobenzene results in increased expression of ANKRD13D mRNA
CTD
PMID:32479839
NCBI chr 1:201,565,712...201,577,987
Ensembl chr 1:201,565,712...201,577,933
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Ankrd33b
ankyrin repeat domain 33B
increases expression
EXP
bromobenzene results in increased expression of ANKRD33B mRNA
CTD
PMID:32479839
NCBI chr 2:82,277,604...82,359,420
Ensembl chr 2:82,283,108...82,358,872
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Anln
anillin, actin binding protein
increases expression
EXP
bromobenzene results in increased expression of ANLN mRNA
CTD
PMID:32479839
NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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Anxa13
annexin A13
increases expression
EXP
bromobenzene results in increased expression of ANXA13 mRNA
CTD
PMID:32479839
NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907
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Apc
APC regulator of WNT signaling pathway
increases expression
EXP
bromobenzene results in increased expression of APC mRNA
CTD
PMID:32479839
NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
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Apoc3
apolipoprotein C3
decreases expression
EXP
bromobenzene results in decreased expression of APOC3 mRNA
CTD
PMID:12628495
NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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Apoh
apolipoprotein H
increases expression
EXP
bromobenzene results in increased expression of APOH mRNA
CTD
PMID:23288050
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
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Apold1
apolipoprotein L domain containing 1
increases expression
EXP
bromobenzene results in increased expression of APOLD1 mRNA
CTD
PMID:32479839
NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
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Apom
apolipoprotein M
increases expression
EXP
bromobenzene results in increased expression of APOM mRNA
CTD
PMID:12628495
NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
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Aptx
aprataxin
decreases expression
EXP
bromobenzene results in decreased expression of APTX mRNA
CTD
PMID:32479839
NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855
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Arg1
arginase 1
affects binding increases expression
EXP
bromobenzene metabolite binds to ARG1 protein bromobenzene results in increased expression of ARG1 mRNA
CTD
PMID:17305373 PMID:32479839
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Arhgap19
Rho GTPase activating protein 19
decreases expression
EXP
bromobenzene results in decreased expression of ARHGAP19 mRNA
CTD
PMID:32479839
NCBI chr 1:240,571,554...240,617,361
Ensembl chr 1:240,580,871...240,617,287
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Arhgap32
Rho GTPase activating protein 32
increases expression
EXP
bromobenzene results in increased expression of ARHGAP32 mRNA
CTD
PMID:32479839
NCBI chr 8:30,421,269...30,681,653
Ensembl chr 8:30,421,515...30,678,454
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Arhgef19
Rho guanine nucleotide exchange factor 19
decreases expression
EXP
bromobenzene results in decreased expression of ARHGEF19 mRNA
CTD
PMID:32479839
NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203
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Arid5a
AT-rich interaction domain 5A
increases expression
EXP
bromobenzene results in increased expression of ARID5A mRNA
CTD
PMID:32479839
NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
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Armc7
armadillo repeat containing 7
increases expression
EXP
bromobenzene results in increased expression of ARMC7 mRNA
CTD
PMID:32479839
NCBI chr10:100,723,080...100,739,636
Ensembl chr10:100,723,105...100,739,636
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Arrdc3
arrestin domain containing 3
decreases expression
EXP
bromobenzene results in decreased expression of ARRDC3 mRNA
CTD
PMID:32479839
NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
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Asb4
ankyrin repeat and SOCS box-containing 4
decreases expression
EXP
bromobenzene results in decreased expression of ASB4 mRNA
CTD
PMID:32479839
NCBI chr 4:33,506,992...33,544,630
Ensembl chr 4:33,506,992...33,544,630
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Asf1a
anti-silencing function 1A histone chaperone
increases expression
EXP
bromobenzene results in increased expression of ASF1A mRNA
CTD
PMID:12628495
NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808
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Asl
argininosuccinate lyase
increases expression
EXP
bromobenzene results in increased expression of ASL mRNA
CTD
PMID:32479839
NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
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Atp12a
ATPase H+/K+ transporting non-gastric alpha2 subunit
increases expression
EXP
bromobenzene results in increased expression of ATP12A mRNA
CTD
PMID:32479839
NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229
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Atp1b1
ATPase Na+/K+ transporting subunit beta 1
increases expression
EXP
bromobenzene results in increased expression of ATP1B1 mRNA
CTD
PMID:32479839
NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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Atp6v0d2
ATPase H+ transporting V0 subunit D2
increases expression
EXP
bromobenzene results in increased expression of ATP6V0D2 mRNA
CTD
PMID:32479839
NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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Atp6v1c2
ATPase H+ transporting V1 subunit C2
increases expression
EXP
bromobenzene results in increased expression of ATP6V1C2 mRNA
CTD
PMID:32479839
NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
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Avpr1a
arginine vasopressin receptor 1A
affects expression
EXP
bromobenzene affects the expression of AVPR1A mRNA
CTD
PMID:32479839
NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
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B3galnt1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
increases expression
EXP
bromobenzene results in increased expression of B3GALNT1 mRNA
CTD
PMID:32479839
NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332
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Baat
bile acid CoA:amino acid N-acyltransferase
decreases expression
EXP
bromobenzene results in decreased expression of BAAT mRNA
CTD
PMID:32479839
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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Bach1
BTB domain and CNC homolog 1
increases expression
EXP
bromobenzene results in increased expression of BACH1 mRNA
CTD
PMID:32479839
NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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Banp
Btg3 associated nuclear protein
decreases expression
EXP
bromobenzene results in decreased expression of BANP mRNA
CTD
PMID:32479839
NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
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Bex1
brain expressed X-linked 1
increases expression
EXP
bromobenzene results in increased expression of BEX2 mRNA
CTD
PMID:32479839
NCBI chr X:99,219,014...99,220,518
Ensembl chr X:99,219,014...99,220,958
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Bhlha15
basic helix-loop-helix family, member a15
decreases expression
EXP
bromobenzene results in decreased expression of BHLHA15 mRNA
CTD
PMID:32479839
NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
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Bhlhe40
basic helix-loop-helix family, member e40
decreases expression
EXP
bromobenzene results in decreased expression of BHLHE40 mRNA
CTD
PMID:32479839
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Bhmt
betaine-homocysteine S-methyltransferase
decreases expression increases expression
EXP
bromobenzene results in decreased expression of BHMT mRNA bromobenzene results in increased expression of BHMT mRNA
CTD
PMID:12628495 PMID:15056800 PMID:32479839
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Bmal1
basic helix-loop-helix ARNT like 1
increases expression
EXP
bromobenzene results in increased expression of BMAL1 mRNA
CTD
PMID:32479839
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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Bmal2
basic helix-loop-helix ARNT like 2
decreases expression
EXP
bromobenzene results in decreased expression of BMAL2 mRNA
CTD
PMID:32479839
NCBI chr 4:179,699,432...179,747,710
Ensembl chr 4:179,699,502...179,746,949
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Bmf
Bcl2 modifying factor
decreases expression
EXP
bromobenzene results in decreased expression of BMF mRNA
CTD
PMID:32479839
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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Brinp2
BMP/retinoic acid inducible neural specific 2
increases expression
EXP
bromobenzene results in increased expression of BRINP2 mRNA
CTD
PMID:32479839
NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
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Btbd19
BTB domain containing 19
increases expression
EXP
bromobenzene results in increased expression of BTBD19 mRNA
CTD
PMID:32479839
NCBI chr 5:130,596,966...130,605,403
Ensembl chr 5:130,597,684...130,604,335
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C14h2orf73
similar to human chromosome 2 open reading frame 73
increases expression
EXP
bromobenzene results in increased expression of C14H2ORF73 mRNA
CTD
PMID:32479839
NCBI chr14:104,145,818...104,178,973
Ensembl chr14:104,145,818...104,178,973
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C1qtnf7
C1q and TNF related 7
increases expression
EXP
bromobenzene results in increased expression of C1QTNF7 mRNA
CTD
PMID:32479839
NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410
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C1r
complement C1r
decreases expression
EXP
bromobenzene results in decreased expression of C1R mRNA
CTD
PMID:12628495
NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
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C8h11orf54
similar to human chromosome 11 open reading frame 54
affects binding
EXP
bromobenzene metabolite binds to C8H11ORF54 protein
CTD
PMID:17305373
NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
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C8h15orf39
similar to human chromosome 15 open reading frame 39
increases expression
EXP
bromobenzene results in increased expression of C8H15ORF39 mRNA
CTD
PMID:32479839
NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941
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C9
complement C9
decreases expression
EXP
bromobenzene results in decreased expression of C9 mRNA
CTD
PMID:12628495
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
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Calml3
calmodulin-like 3
increases expression
EXP
bromobenzene results in increased expression of CALML3 mRNA
CTD
PMID:32479839
NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
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Capn1
calpain 1
decreases expression
EXP
bromobenzene results in decreased expression of CAPN1 mRNA
CTD
PMID:15056800
NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
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Car1
carbonic anhydrase 1
decreases expression
EXP
bromobenzene results in decreased expression of CAR1 mRNA
CTD
PMID:32479839
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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Car12
carbonic anhydrase 12
increases expression
EXP
bromobenzene results in increased expression of CA12 mRNA
CTD
PMID:32479839
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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Car2
carbonic anhydrase 2
increases expression
EXP
bromobenzene results in increased expression of CAR2 mRNA
CTD
PMID:32479839
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car3
carbonic anhydrase 3
affects binding decreases expression
EXP
bromobenzene metabolite binds to CA3 protein bromobenzene results in decreased expression of CA3 mRNA
CTD
PMID:17305373 PMID:32479839
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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Card19
caspase recruitment domain family, member 19
increases expression
EXP
bromobenzene results in increased expression of CARD19 mRNA
CTD
PMID:32479839
NCBI chr17:15,432,632...15,445,317
Ensembl chr17:15,432,612...15,445,318
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Cblc
Cbl proto-oncogene C
decreases expression
EXP
bromobenzene results in decreased expression of CBLC mRNA
CTD
PMID:32479839
NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
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Ccdc106
coiled-coil domain containing 106
increases expression
EXP
bromobenzene results in increased expression of CCDC106 mRNA
CTD
PMID:32479839
NCBI chr 1:68,779,882...68,783,975
Ensembl chr 1:68,779,882...68,786,846
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Ccdc122
coiled-coil domain containing 122
increases expression
EXP
bromobenzene results in increased expression of CCDC122 mRNA
CTD
PMID:32479839
NCBI chr15:52,407,717...52,470,163
Ensembl chr15:52,407,717...52,470,163
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Ccdc96
coiled-coil domain containing 96
increases expression
EXP
bromobenzene results in increased expression of CCDC96 mRNA
CTD
PMID:32479839
NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
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Ccl7
C-C motif chemokine ligand 7
decreases expression
EXP
bromobenzene results in decreased expression of CCL7 mRNA
CTD
PMID:32479839
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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Ccn2
cellular communication network factor 2
increases expression
EXP
bromobenzene results in increased expression of CCN2 mRNA
CTD
PMID:32479839
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccnd1
cyclin D1
decreases expression
EXP
bromobenzene results in decreased expression of CCND1 mRNA
CTD
PMID:32479839
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccne1
cyclin E1
decreases expression
EXP
bromobenzene results in decreased expression of CCNE1 mRNA
CTD
PMID:32479839
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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Ccser2
coiled-coil serine-rich protein 2
increases expression
EXP
bromobenzene results in increased expression of CCSER2 mRNA
CTD
PMID:32479839
NCBI chr16:12,613,103...12,725,764
Ensembl chr16:12,613,103...12,725,738
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Cd274
CD274 molecule
decreases expression
EXP
bromobenzene results in decreased expression of CD274 mRNA
CTD
PMID:32479839
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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Cd3e
CD3 epsilon subunit of T-cell receptor complex
increases expression
EXP
bromobenzene results in increased expression of CD3E mRNA
CTD
PMID:32479839
NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
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Cd99l2
CD99 molecule-like 2
increases expression
EXP
bromobenzene results in increased expression of CD99L2 mRNA
CTD
PMID:32479839
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Cdc34
cell division cycle 34, ubiqiutin conjugating enzyme
increases expression
EXP
bromobenzene results in increased expression of CDC34 mRNA
CTD
PMID:15056800
NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
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Cdh10
cadherin 10
increases expression
EXP
bromobenzene results in increased expression of CDH10 mRNA
CTD
PMID:32479839
NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
EXP
bromobenzene results in increased expression of CDKN1A mRNA
CTD
PMID:32479839
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdo1
cysteine dioxygenase type 1
decreases expression increases expression
EXP
bromobenzene results in decreased expression of CDO1 mRNA bromobenzene results in increased expression of CDO1 mRNA
CTD
PMID:12628495 PMID:15056800
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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Cds2
CDP-diacylglycerol synthase 2
increases expression
EXP
bromobenzene results in increased expression of CDS2 mRNA
CTD
PMID:32479839
NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
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Cdt1
chromatin licensing and DNA replication factor 1
decreases expression
EXP
bromobenzene results in decreased expression of CDT1 mRNA
CTD
PMID:32479839
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
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Cebpd
CCAAT/enhancer binding protein delta
decreases expression
EXP
bromobenzene results in decreased expression of CEBPD mRNA
CTD
PMID:12628495
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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Cemip
cell migration inducing hyaluronidase 1
increases expression
EXP
bromobenzene results in increased expression of CEMIP mRNA
CTD
PMID:32479839
NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
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Cenpk
centromere protein K
decreases expression
EXP
bromobenzene results in decreased expression of CENPK mRNA
CTD
PMID:32479839
NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706
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Cenpt
centromere protein T
increases expression
EXP
bromobenzene results in increased expression of CENPT mRNA
CTD
PMID:32479839
NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
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Cenpw
centromere protein W
increases expression
EXP
bromobenzene results in increased expression of CENPW mRNA
CTD
PMID:32479839
NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
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Cfap95
cilia and flagella associated protein 95
decreases expression
EXP
bromobenzene results in decreased expression of CFAP95 mRNA
CTD
PMID:32479839
NCBI chr 1:221,123,786...221,242,963
Ensembl chr 1:221,131,813...221,242,963
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Cfl1
cofilin 1
increases expression
EXP
bromobenzene results in increased expression of CFL1 mRNA
CTD
PMID:12628495
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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Chac1
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
increases expression
EXP
bromobenzene results in increased expression of CHAC1 mRNA
CTD
PMID:32479839
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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Chmp4c
charged multivesicular body protein 4C
increases expression
EXP
bromobenzene results in increased expression of CHMP4C mRNA
CTD
PMID:32479839
NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668
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Chrdl1
chordin-like 1
decreases expression
EXP
bromobenzene results in decreased expression of CHRDL1 mRNA
CTD
PMID:32479839
NCBI chr X:106,889,125...106,992,937
Ensembl chr X:106,889,125...106,992,921
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Chrna1
cholinergic receptor nicotinic alpha 1 subunit
increases expression
EXP
bromobenzene results in increased expression of CHRNA1 mRNA
CTD
PMID:32479839
NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840
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Chrna5
cholinergic receptor nicotinic alpha 5 subunit
increases expression
EXP
bromobenzene results in increased expression of CHRNA5 mRNA
CTD
PMID:32479839
NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
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Ciart
circadian associated repressor of transcription
decreases expression
EXP
bromobenzene results in decreased expression of CIART mRNA
CTD
PMID:32479839
NCBI chr 2:183,419,819...183,424,845
Ensembl chr 2:183,419,819...183,423,313
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Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
affects expression
EXP
bromobenzene affects the expression of CITED4 mRNA
CTD
PMID:32479839
NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
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Clcf1
cardiotrophin-like cytokine factor 1
increases expression
EXP
bromobenzene results in increased expression of CLCF1 mRNA
CTD
PMID:32479839
NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
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Cldn1
claudin 1
increases expression
EXP
bromobenzene results in increased expression of CLDN1 mRNA
CTD
PMID:32479839
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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Cldn3
claudin 3
decreases expression
EXP
bromobenzene results in decreased expression of CLDN3 mRNA
CTD
PMID:32479839
NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
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Clec2dl1
C-type lectin domain family 2 member D-like 1
increases expression
EXP
bromobenzene results in increased expression of CLEC2DL1 mRNA
CTD
PMID:32479839
NCBI chr 4:162,263,635...162,274,882
Ensembl chr 4:162,263,639...162,274,880
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Clock
clock circadian regulator
increases expression
EXP
bromobenzene results in increased expression of CLOCK mRNA
CTD
PMID:32479839
NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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Clspn
claspin
decreases expression
EXP
bromobenzene results in decreased expression of CLSPN mRNA
CTD
PMID:32479839
NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
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Clstn3
calsyntenin 3
decreases expression
EXP
bromobenzene results in decreased expression of CLSTN3 mRNA
CTD
PMID:32479839
NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
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Cltb
clathrin, light chain B
increases expression
EXP
bromobenzene results in increased expression of CLTB mRNA
CTD
PMID:12628495
NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
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Cntnap4
contactin associated protein family member 4
decreases expression
EXP
bromobenzene results in decreased expression of CNTNAP4 mRNA
CTD
PMID:32479839
NCBI chr19:40,568,684...40,861,879
Ensembl chr19:40,568,684...40,854,656
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Colq
collagen like tail subunit of asymmetric acetylcholinesterase
increases expression
EXP
bromobenzene results in increased expression of COLQ mRNA
CTD
PMID:32479839
NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107
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Coq10b
coenzyme Q10B
affects expression
EXP
bromobenzene affects the expression of COQ10B mRNA
CTD
PMID:32479839
NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663
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Coro6
coronin 6
increases expression
EXP
bromobenzene results in increased expression of CORO6 mRNA
CTD
PMID:32479839
NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659
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Cpeb2
cytoplasmic polyadenylation element binding protein 2
increases expression
EXP
bromobenzene results in increased expression of CPEB2 mRNA
CTD
PMID:32479839
NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743
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Cpne1
copine 1
increases expression
EXP
bromobenzene results in increased expression of CPNE1 mRNA
CTD
PMID:32479839
NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636
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Crat
carnitine O-acetyltransferase
increases expression
EXP
bromobenzene results in increased expression of CRAT mRNA
CTD
PMID:32479839
NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
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Creb3l3
cAMP responsive element binding protein 3-like 3
increases expression
EXP
bromobenzene results in increased expression of CREB3L3 mRNA
CTD
PMID:32479839
NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
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Creg1
cellular repressor of E1A-stimulated genes 1
increases expression
EXP
bromobenzene results in increased expression of CREG1 mRNA
CTD
PMID:32479839
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
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Crmp1
collapsin response mediator protein 1
affects expression
EXP
bromobenzene affects the expression of CRMP1 mRNA
CTD
PMID:32479839
NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177
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Cry1
cryptochrome circadian regulator 1
decreases expression
EXP
bromobenzene results in decreased expression of CRY1 mRNA
CTD
PMID:32479839
NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
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Cryga
crystallin, gamma A
decreases expression
EXP
bromobenzene results in decreased expression of CRYGA mRNA
CTD
PMID:32479839
NCBI chr 9:66,482,176...66,484,638
Ensembl chr 9:66,482,176...66,509,896
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Csad
cysteine sulfinic acid decarboxylase
increases expression
EXP
bromobenzene results in increased expression of CSAD mRNA
CTD
PMID:12628495
NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
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Csmd1
CUB and Sushi multiple domains 1
increases expression
EXP
bromobenzene results in increased expression of CSMD1 mRNA
CTD
PMID:32479839
NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
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Csnk2b
casein kinase 2 beta
increases expression
EXP
bromobenzene results in increased expression of CSNK2B mRNA
CTD
PMID:16036859
NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
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Ctsl
cathepsin L
increases expression
EXP
bromobenzene results in increased expression of CTSL mRNA
CTD
PMID:12628495
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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Cux2
cut-like homeobox 2
increases expression
EXP
bromobenzene results in increased expression of CUX2 mRNA
CTD
PMID:32479839
NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806
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Cxcl13
C-X-C motif chemokine ligand 13
decreases expression
EXP
bromobenzene results in decreased expression of CXCL13 mRNA
CTD
PMID:32479839
NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
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Cxcr6
C-X-C motif chemokine receptor 6
decreases expression
EXP
bromobenzene results in decreased expression of CXCR6 mRNA
CTD
PMID:32479839
NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526
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Cyb5a
cytochrome b5 type A
increases expression
EXP
bromobenzene results in increased expression of CYB5A mRNA
CTD
PMID:12628495
NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
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Cycs
cytochrome c, somatic
increases expression
EXP
bromobenzene results in increased expression of CYCS mRNA
CTD
PMID:12628495
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
increases expression
EXP
bromobenzene results in increased expression of CYP17A1 mRNA
CTD
PMID:32479839
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
affects expression
EXP
bromobenzene affects the expression of CYP1A1 protein
CTD
PMID:10445401
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
increases expression
EXP
bromobenzene results in increased expression of CYP26A1 mRNA
CTD
PMID:32479839
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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Cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
decreases expression
EXP
bromobenzene results in decreased expression of CYP26B1 mRNA
CTD
PMID:32479839
NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
increases expression
EXP
bromobenzene results in increased expression of CYP27B1 mRNA
CTD
PMID:32479839
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression
EXP
bromobenzene results in increased expression of CYP2B2 mRNA
CTD
PMID:32479839
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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Cyp2c12
cytochrome P450, family 2, subfamily c, polypeptide 12
increases expression
EXP
bromobenzene results in increased expression of CYP2C12 mRNA
CTD
PMID:32479839
NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases expression
EXP
bromobenzene results in increased expression of CYP2E1 mRNA
CTD
PMID:12628495
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
decreases expression
EXP
bromobenzene results in decreased expression of CYP3A9 mRNA
CTD
PMID:17538237
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Cyp4a3
cytochrome P450, family 4, subfamily a, polypeptide 3
increases expression
EXP
bromobenzene results in increased expression of CYP4A3 mRNA
CTD
PMID:15056800
NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
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Cyp51
cytochrome P450, family 51
decreases expression
EXP
bromobenzene results in decreased expression of CYP51 mRNA
CTD
PMID:12628495 PMID:32479839
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases expression
EXP
bromobenzene results in increased expression of CYP7A1 mRNA
CTD
PMID:32479839
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Cyp8b1
cytochrome P450 family 8 subfamily B member 1
affects expression
EXP
bromobenzene affects the expression of CYP8B1 mRNA
CTD
PMID:32479839
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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Dbp
D-box binding PAR bZIP transcription factor
decreases expression
EXP
bromobenzene results in decreased expression of DBP mRNA
CTD
PMID:32479839
NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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Ddit3
DNA-damage inducible transcript 3
decreases expression
EXP
bromobenzene results in decreased expression of DDIT3 mRNA
CTD
PMID:32479839
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddt
D-dopachrome tautomerase
affects binding
EXP
bromobenzene metabolite binds to DDT protein
CTD
PMID:17305373
NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
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Depp1
DEPP autophagy regulator 1
increases expression
EXP
bromobenzene results in increased expression of DEPP1 mRNA
CTD
PMID:32479839
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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Derl3
derlin 3
decreases expression
EXP
bromobenzene results in decreased expression of DERL3 mRNA
CTD
PMID:32479839
NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
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Dhcr7
7-dehydrocholesterol reductase
decreases expression
EXP
bromobenzene results in decreased expression of DHCR7 mRNA
CTD
PMID:32479839
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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Dhx40
DEAH-box helicase 40
increases expression
EXP
bromobenzene results in increased expression of DHX40 mRNA
CTD
PMID:32479839
NCBI chr10:71,584,546...71,621,479
Ensembl chr10:71,583,716...71,621,445
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Dipk1c
divergent protein kinase domain 1C
increases expression
EXP
bromobenzene results in increased expression of DIPK1C mRNA
CTD
PMID:32479839
NCBI chr18:78,087,972...78,109,910
Ensembl chr18:78,087,991...78,109,904
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Disp1
dispatched RND transporter family member 1
increases expression
EXP
bromobenzene results in increased expression of DISP1 mRNA
CTD
PMID:32479839
NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702
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Dlgap5
DLG associated protein 5
increases expression
EXP
bromobenzene results in increased expression of DLGAP5 mRNA
CTD
PMID:32479839
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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Dmtn
dematin actin binding protein
decreases expression
EXP
bromobenzene results in decreased expression of DMTN mRNA
CTD
PMID:32479839
NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601
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Dnah17
dynein, axonemal, heavy chain 17
increases expression
EXP
bromobenzene results in increased expression of DNAH17 mRNA
CTD
PMID:32479839
NCBI chr10:103,244,144...103,364,953
Ensembl chr10:103,249,363...103,364,901
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Dnase1l2
deoxyribonuclease 1 like 2
increases expression
EXP
bromobenzene results in increased expression of DNASE1L2 mRNA
CTD
PMID:32479839
NCBI chr10:13,471,850...13,473,447
Ensembl chr10:13,471,479...13,473,763
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Dnmt3b
DNA methyltransferase 3 beta
increases expression
EXP
bromobenzene results in increased expression of DNMT3B mRNA
CTD
PMID:32479839
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Dok7
docking protein 7
increases expression
EXP
bromobenzene results in increased expression of DOK7 mRNA
CTD
PMID:32479839
NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386
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Dpp6
dipeptidyl peptidase like 6
decreases expression
EXP
bromobenzene results in decreased expression of DPP6 mRNA
CTD
PMID:32479839
NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532
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Dr1
down-regulator of transcription 1
increases expression
EXP
bromobenzene results in increased expression of DR1 mRNA
CTD
PMID:32479839
NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
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Dsc2
desmocollin 2
increases expression
EXP
bromobenzene results in increased expression of DSC2 mRNA
CTD
PMID:32479839
NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
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Dtx3
deltex E3 ubiquitin ligase 3
increases expression
EXP
bromobenzene results in increased expression of DTX3 mRNA
CTD
PMID:32479839
NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
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Duoxa1
dual oxidase maturation factor 1
decreases expression
EXP
bromobenzene results in decreased expression of DUOXA1 mRNA
CTD
PMID:32479839
NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499
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Dus4l
dihydrouridine synthase 4-like
increases expression
EXP
bromobenzene results in increased expression of DUS4L mRNA
CTD
PMID:32479839
NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449
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Dusp6
dual specificity phosphatase 6
decreases expression
EXP
bromobenzene results in decreased expression of DUSP6 mRNA
CTD
PMID:32479839
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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Dusp8
dual specificity phosphatase 8
increases expression
EXP
bromobenzene results in increased expression of DUSP8 mRNA
CTD
PMID:32479839
NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
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Dynlt4
dynein light chain Tctex-type 4
increases expression
EXP
bromobenzene results in increased expression of DYNLT4 mRNA
CTD
PMID:32479839
NCBI chr 5:130,605,437...130,607,224
Ensembl chr 5:130,605,399...130,607,666
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E2f7
E2F transcription factor 7
increases expression
EXP
bromobenzene results in increased expression of E2F7 mRNA
CTD
PMID:32479839
NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
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Eci1
enoyl-CoA delta isomerase 1
increases expression
EXP
bromobenzene results in increased expression of ECI1 mRNA
CTD
PMID:12628495
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
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Ecm2
extracellular matrix protein 2
increases expression
EXP
bromobenzene results in increased expression of ECM2 mRNA
CTD
PMID:32479839
NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
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Edar
ectodysplasin-A receptor
decreases expression
EXP
bromobenzene results in decreased expression of EDAR mRNA
CTD
PMID:32479839
NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494
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Eea1
early endosome antigen 1
increases expression
EXP
bromobenzene results in increased expression of EEA1 mRNA
CTD
PMID:32479839
NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
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Egln1
egl-9 family hypoxia-inducible factor 1
multiple interactions
EXP
[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HIF1A protein; [bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HMOX1 mRNA; [bromobenzene co-treated with EGLN1 mutant form] results in increased expression of PTGS2 mRNA
CTD
PMID:24190904
NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
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Eif3c
eukaryotic translation initiation factor 3, subunit C
increases expression
EXP
bromobenzene results in increased expression of EIF3C mRNA
CTD
PMID:12628495
NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
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Eif5a
eukaryotic translation initiation factor 5A
increases expression
EXP
bromobenzene results in increased expression of EIF5A mRNA
CTD
PMID:12628495
NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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Eno1
enolase 1
affects binding
EXP
bromobenzene metabolite binds to ENO1 protein
CTD
PMID:17305373
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
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Enpp7
ectonucleotide pyrophosphatase/phosphodiesterase 7
decreases expression
EXP
bromobenzene results in decreased expression of ENPP7 mRNA
CTD
PMID:32479839
NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589
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Ephx1
epoxide hydrolase 1
increases expression
EXP
bromobenzene results in increased expression of EPHX1 mRNA
CTD
PMID:12628495 PMID:17538237 PMID:32479839
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Epop
elongin BC and polycomb repressive complex 2 associated protein
increases expression
EXP
bromobenzene results in increased expression of EPOP mRNA
CTD
PMID:32479839
NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912
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Eps8l3
EPS8 like 3
increases expression
EXP
bromobenzene results in increased expression of EPS8L3 mRNA
CTD
PMID:32479839
NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085
G
Erich5
glutamate-rich 5
decreases expression
EXP
bromobenzene results in decreased expression of ERICH5 mRNA
CTD
PMID:32479839
NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207
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Ero1b
endoplasmic reticulum oxidoreductase 1 beta
increases expression
EXP
bromobenzene results in increased expression of ERO1B mRNA
CTD
PMID:32479839
NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
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Erp29
endoplasmic reticulum protein 29
affects binding
EXP
bromobenzene metabolite binds to ERP29 protein
CTD
PMID:12018992
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Etnppl
ethanolamine-phosphate phospho-lyase
increases expression
EXP
bromobenzene results in increased expression of ETNPPL mRNA
CTD
PMID:32479839
NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212
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Eva1c
eva-1 homolog C
increases expression
EXP
bromobenzene results in increased expression of EVA1C mRNA
CTD
PMID:32479839
NCBI chr11:30,089,510...30,163,596
Ensembl chr11:30,089,365...30,163,596
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F12
coagulation factor XII
increases expression
EXP
bromobenzene results in increased expression of F12 mRNA
CTD
PMID:32479839
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
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Fabp1
fatty acid binding protein 1
decreases expression affects binding
EXP
bromobenzene results in decreased expression of FABP1 mRNA bromobenzene metabolite binds to FABP1 protein
CTD
PMID:12628495 PMID:17305373
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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Fabp12
fatty acid binding protein 12
increases expression
EXP
bromobenzene results in increased expression of FABP12 mRNA
CTD
PMID:32479839
NCBI chr 2:91,539,568...91,554,999
Ensembl chr 2:91,500,539...91,554,996
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Fabp7
fatty acid binding protein 7
affects binding
EXP
bromobenzene metabolite binds to FABP7 protein
CTD
PMID:17305373
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
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Fads1
fatty acid desaturase 1
decreases expression
EXP
bromobenzene results in decreased expression of FADS1 mRNA
CTD
PMID:32479839
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
G
Fads2
fatty acid desaturase 2
decreases expression
EXP
bromobenzene results in decreased expression of FADS2 mRNA
CTD
PMID:32479839
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
G
Fah
fumarylacetoacetate hydrolase
affects binding
EXP
bromobenzene metabolite binds to FAH protein
CTD
PMID:17305373
NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
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Fam180a
family with sequence similarity 180, member A
increases expression
EXP
bromobenzene results in increased expression of FAM180A mRNA
CTD
PMID:32479839
NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047
G
Fam222a
family with sequence similarity 222, member A
increases expression
EXP
bromobenzene results in increased expression of FAM222A mRNA
CTD
PMID:32479839
NCBI chr12:41,982,064...42,033,085
Ensembl chr12:41,986,780...42,033,682
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Fam83d
family with sequence similarity 83, member D
increases expression
EXP
bromobenzene results in increased expression of FAM83D mRNA
CTD
PMID:32479839
NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
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Fam83f
family with sequence similarity 83, member F
increases expression
EXP
bromobenzene results in increased expression of FAM83F mRNA
CTD
PMID:32479839
NCBI chr 7:112,211,164...112,240,454
Ensembl chr 7:112,211,164...112,240,452
G
Fam89a
family with sequence similarity 89, member A
decreases expression
EXP
bromobenzene results in decreased expression of FAM89A mRNA
CTD
PMID:32479839
NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631
G
Fasn
fatty acid synthase
decreases expression
EXP
bromobenzene results in decreased expression of FASN mRNA
CTD
PMID:32479839
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fbn2
fibrillin 2
increases expression
EXP
bromobenzene results in increased expression of FBN2 mRNA
CTD
PMID:32479839
NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976
G
Fbxo30
F-box protein 30
increases expression
EXP
bromobenzene results in increased expression of FBXO30 mRNA
CTD
PMID:32479839
NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441
G
Fcamr
Fc alpha and mu receptor
increases expression
EXP
bromobenzene results in increased expression of FCAMR mRNA
CTD
PMID:32479839
NCBI chr13:42,273,891...42,288,002
Ensembl chr13:42,273,628...42,287,113
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
decreases expression
EXP
bromobenzene results in decreased expression of FDFT1 mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
G
Fdps
farnesyl diphosphate synthase
decreases expression
EXP
bromobenzene results in decreased expression of FDPS mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
G
Fen1
flap structure-specific endonuclease 1
decreases expression
EXP
bromobenzene results in decreased expression of FEN1 mRNA
CTD
PMID:32479839
NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
G
Fgf21
fibroblast growth factor 21
increases expression
EXP
bromobenzene results in increased expression of FGF21 mRNA
CTD
PMID:32479839
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
G
Fgg
fibrinogen gamma chain
decreases expression
EXP
bromobenzene results in decreased expression of FGG mRNA
CTD
PMID:12628495
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
G
Fgl1
fibrinogen-like 1
decreases expression
EXP
bromobenzene results in decreased expression of FGL1 mRNA
CTD
PMID:12628495
NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
G
Fgr
FGR proto-oncogene, Src family tyrosine kinase
decreases expression
EXP
bromobenzene results in decreased expression of FGR mRNA
CTD
PMID:32479839
NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
G
Fibin
fin bud initiation factor homolog
increases expression
EXP
bromobenzene results in increased expression of FIBIN mRNA
CTD
PMID:32479839
NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
G
Fkbp5
FKBP prolyl isomerase 5
increases expression
EXP
bromobenzene results in increased expression of FKBP5 mRNA
CTD
PMID:32479839
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
G
Flii
FLII, actin remodeling protein
increases expression
EXP
bromobenzene results in increased expression of FLII mRNA
CTD
PMID:12628495 PMID:16036859
NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970
G
Flnb
filamin B
increases expression
EXP
bromobenzene results in increased expression of FLNB mRNA
CTD
PMID:32479839
NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
G
Flvcr2
FLVCR choline and putative heme transporter 2
increases expression
EXP
bromobenzene results in increased expression of FLVCR2 mRNA
CTD
PMID:32479839
NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353
G
Fmnl1
formin-like 1
decreases expression
EXP
bromobenzene results in decreased expression of FMNL1 mRNA
CTD
PMID:32479839
NCBI chr10:88,115,876...88,143,342
Ensembl chr10:88,116,009...88,143,357
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
increases expression
EXP
bromobenzene results in increased expression of FMO1 mRNA
CTD
PMID:15056800
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
G
Fmo2
flavin containing dimethylaniline monoxygenase 2
increases expression
EXP
bromobenzene results in increased expression of FMO2 mRNA
CTD
PMID:32479839
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
G
Fmo3
flavin containing dimethylaniline monoxygenase 3
increases expression
EXP
bromobenzene results in increased expression of FMO3 mRNA
CTD
PMID:32479839
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
G
Fn1
fibronectin 1
decreases expression
EXP
bromobenzene results in decreased expression of FN1 mRNA
CTD
PMID:12628495
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
G
Fndc1
fibronectin type III domain containing 1
increases expression
EXP
bromobenzene results in increased expression of FNDC1 mRNA
CTD
PMID:32479839
NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:47,281,844...47,364,259
G
Fosl1
FOS like 1, AP-1 transcription factor subunit
decreases expression
EXP
bromobenzene results in decreased expression of FOSL1 mRNA
CTD
PMID:32479839
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
G
Fstl3
follistatin like 3
increases expression
EXP
bromobenzene results in increased expression of FSTL3 mRNA
CTD
PMID:32479839
NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639
G
Fth1
ferritin heavy chain 1
increases expression
EXP
bromobenzene results in increased expression of FTH1 mRNA
CTD
PMID:12628495
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Fut1
fucosyltransferase 1
increases expression
EXP
bromobenzene results in increased expression of FUT1 mRNA
CTD
PMID:32479839
NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
G
Fzd7
frizzled class receptor 7
increases expression
EXP
bromobenzene results in increased expression of FZD7 mRNA
CTD
PMID:32479839
NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
G
G6pd
glucose-6-phosphate dehydrogenase
increases expression
EXP
bromobenzene results in increased expression of G6PDX mRNA
CTD
PMID:12628495
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gad2
glutamate decarboxylase 2
increases expression
EXP
bromobenzene results in increased expression of GAD2 mRNA
CTD
PMID:32479839
NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
EXP
bromobenzene results in increased expression of GADD45A mRNA
CTD
PMID:32479839
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
EXP
bromobenzene results in increased expression of GADD45B mRNA
CTD
PMID:32479839
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
decreases expression
EXP
bromobenzene results in decreased expression of GADD45G mRNA
CTD
PMID:32479839
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
G
Gal3st1
galactose-3-O-sulfotransferase 1
increases expression
EXP
bromobenzene results in increased expression of GAL3ST1 mRNA
CTD
PMID:32479839
NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
G
Galnt2
polypeptide N-acetylgalactosaminyltransferase 2
decreases expression
EXP
bromobenzene results in decreased expression of GALNT2 mRNA
CTD
PMID:32479839
NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
G
Gamt
guanidinoacetate N-methyltransferase
affects binding
EXP
bromobenzene metabolite binds to GAMT protein
CTD
PMID:17305373
NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778
G
Gast
gastrin
decreases expression
EXP
bromobenzene results in decreased expression of GAST mRNA
CTD
PMID:15976192
NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
G
Gba3
glucosylceramidase beta 3
increases expression
EXP
bromobenzene results in increased expression of GBA3 mRNA
CTD
PMID:32479839
NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653
G
Gbp2
guanylate binding protein 2
decreases expression
EXP
bromobenzene results in decreased expression of GBP2 mRNA
CTD
PMID:32479839
NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
G
Gbp3
guanylate binding protein 3
decreases expression
EXP
bromobenzene results in decreased expression of GBP3 mRNA
CTD
PMID:32479839
NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098
G
Gc
GC, vitamin D binding protein
increases expression
EXP
bromobenzene results in increased expression of GC mRNA
CTD
PMID:15056800 PMID:23288050
NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
bromobenzene results in increased expression of GCLC protein
CTD
PMID:18078705
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
EXP
bromobenzene results in increased expression of GCLM mRNA
CTD
PMID:12628495
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdf15
growth differentiation factor 15
increases expression
EXP
bromobenzene results in increased expression of GDF15 mRNA
CTD
PMID:32479839
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gem
GTP binding protein overexpressed in skeletal muscle
increases expression
EXP
bromobenzene results in increased expression of GEM mRNA
CTD
PMID:32479839
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
G
Gfm1
G elongation factor, mitochondrial 1
increases expression
EXP
bromobenzene results in increased expression of GFM1 mRNA
CTD
PMID:12628495
NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
G
Ghrhr
growth hormone releasing hormone receptor
decreases response to substance
ISO
GHRHR gene mutant form results in decreased susceptibility to bromobenzene
CTD
PMID:17521389
NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776
G
Gimd1
GIMAP family P-loop NTPase domain containing 1
decreases expression
EXP
bromobenzene results in decreased expression of GIMD1 mRNA
CTD
PMID:32479839
NCBI chr 2:221,103,878...221,138,559
Ensembl chr 2:221,103,878...221,138,553
G
Gja4
gap junction protein, alpha 4
increases expression
EXP
bromobenzene results in increased expression of GJA4 mRNA
CTD
PMID:32479839
NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
G
Gjb2
gap junction protein, beta 2
increases expression
EXP
bromobenzene results in increased expression of GJB2 mRNA
CTD
PMID:32479839
NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
G
Gli3
GLI family zinc finger 3
increases expression
EXP
bromobenzene results in increased expression of GLI3 mRNA
CTD
PMID:32479839
NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
G
Glud1
glutamate dehydrogenase 1
increases activity
EXP
bromobenzene results in increased activity of GLUD1 protein
CTD
PMID:3012827
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Gnat1
G protein subunit alpha transducin 1
increases expression
EXP
bromobenzene results in increased expression of GNAT1 mRNA
CTD
PMID:32479839
NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
G
Gnmt
glycine N-methyltransferase
affects binding
EXP
bromobenzene metabolite binds to GNMT protein
CTD
PMID:17305373
NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
G
Got1
glutamic-oxaloacetic transaminase 1
increases expression
EXP
bromobenzene results in increased expression of GOT1 mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Gpat3
glycerol-3-phosphate acyltransferase 3
increases expression
EXP
bromobenzene results in increased expression of GPAT3 mRNA
CTD
PMID:32479839
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
G
Gpatch4
G patch domain containing 4
increases expression
EXP
bromobenzene results in increased expression of GPATCH4 mRNA
CTD
PMID:32479839
NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684
G
Gpbp1l1
GC-rich promoter binding protein 1-like 1
increases expression
EXP
bromobenzene results in increased expression of GPBP1L1 mRNA
CTD
PMID:32479839
NCBI chr 5:130,009,768...130,050,636
Ensembl chr 5:130,023,137...130,050,459
G
Gpd1
glycerol-3-phosphate dehydrogenase 1
affects binding
EXP
bromobenzene metabolite binds to GPD1 protein
CTD
PMID:17305373
NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
G
Gpr21
G protein-coupled receptor 21
decreases expression
EXP
bromobenzene results in decreased expression of GPR21 mRNA
CTD
PMID:32479839
NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:21,275,007...21,277,930
G
Gpr39
G protein-coupled receptor 39
increases expression
EXP
bromobenzene results in increased expression of GPR39 mRNA
CTD
PMID:32479839
NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267
G
Gpr65
G-protein coupled receptor 65
decreases expression
EXP
bromobenzene results in decreased expression of GPR65 mRNA
CTD
PMID:32479839
NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
G
Gprin3
GPRIN family member 3
decreases expression
EXP
bromobenzene results in decreased expression of GPRIN3 mRNA
CTD
PMID:32479839
NCBI chr 4:88,572,062...88,657,369
Ensembl chr 4:88,563,607...88,657,429
G
Gpt
glutamic--pyruvic transaminase
multiple interactions increases activity
ISO EXP
diisopropyl 1,3-dithiol-2-ylidenemalonate inhibits the reaction [bromobenzene results in increased activity of GPT protein]
CTD
PMID:3795300 PMID:32479839
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpx1
glutathione peroxidase 1
decreases expression
EXP
bromobenzene results in decreased expression of GPX1 mRNA
CTD
PMID:12628495
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx2
glutathione peroxidase 2
increases expression
EXP
bromobenzene results in increased expression of GPX2 mRNA
CTD
PMID:17538237
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Gsta2
glutathione S-transferase alpha 2
increases expression
EXP
bromobenzene results in increased expression of GSTA2 mRNA
CTD
PMID:12628495
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gsta5
glutathione S-transferase alpha 5
increases expression
EXP
bromobenzene results in increased expression of GSTA5 mRNA
CTD
PMID:17538237
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Gstm1
glutathione S-transferase mu 1
increases expression affects binding
EXP
bromobenzene results in increased expression of GSTM1 mRNA bromobenzene metabolite binds to GSTM1 protein
CTD
PMID:12628495 PMID:17305373
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gstm2
glutathione S-transferase mu 2
affects binding
EXP
bromobenzene metabolite binds to GSTM2 protein
CTD
PMID:17305373
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
Gstp3
glutathione S-transferase pi 3
decreases expression
EXP
bromobenzene results in decreased expression of GSTP3 mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr 1:201,355,682...201,358,216
Ensembl chr 1:201,355,682...201,358,330
G
Gstt1
glutathione S-transferase theta 1
decreases expression
EXP
bromobenzene results in decreased expression of GSTT1 mRNA
CTD
PMID:15056800
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gucy1b2
guanylate cyclase 1 soluble subunit beta 2
decreases expression
EXP
bromobenzene results in decreased expression of GUCY1B2 mRNA
CTD
PMID:32479839
NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441
G
Gzma
granzyme A
decreases expression
EXP
bromobenzene results in decreased expression of GZMA mRNA
CTD
PMID:32479839
NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
G
Hamp
hepcidin antimicrobial peptide
decreases expression
EXP
bromobenzene results in decreased expression of HAMP mRNA
CTD
PMID:32479839
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
G
Hao2
hydroxyacid oxidase 2
decreases expression
EXP
bromobenzene results in decreased expression of HAO2 mRNA
CTD
PMID:32479839
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
G
Hba-a1
hemoglobin alpha, adult chain 1
decreases expression
EXP
bromobenzene results in decreased expression of HBA-A1 mRNA
CTD
PMID:12628495
NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392
G
Hbb
hemoglobin subunit beta
affects binding
EXP
bromobenzene metabolite binds to HBB protein
CTD
PMID:17305373
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
G
Hbegf
heparin-binding EGF-like growth factor
increases expression
EXP
bromobenzene results in increased expression of HBEGF mRNA
CTD
PMID:32479839
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
G
Hemgn
hemogen
increases expression
EXP
bromobenzene results in increased expression of HEMGN mRNA
CTD
PMID:32479839
NCBI chr 5:60,679,633...60,698,597
Ensembl chr 5:60,679,633...60,698,669
G
Hes6
hes family bHLH transcription factor 6
decreases expression
EXP
bromobenzene results in decreased expression of HES6 mRNA
CTD
PMID:32479839
NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
G
Hhip
Hedgehog-interacting protein
decreases expression
EXP
bromobenzene results in decreased expression of HHIP mRNA
CTD
PMID:32479839
NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
G
Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
EXP
[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HIF1A protein
CTD
PMID:24190904
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hif3a
hypoxia inducible factor 3 subunit alpha
increases expression
EXP
bromobenzene results in increased expression of HIF3A mRNA
CTD
PMID:32479839
NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
G
Hjurp
Holliday junction recognition protein
increases expression
EXP
bromobenzene results in increased expression of HJURP mRNA
CTD
PMID:32479839
NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
G
Hjv
hemojuvelin BMP co-receptor
increases expression
EXP
bromobenzene results in increased expression of HJV mRNA
CTD
PMID:32479839
NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850
G
Hk3
hexokinase 3
decreases expression
EXP
bromobenzene results in decreased expression of HK3 mRNA
CTD
PMID:32479839
NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863
G
Hlf
HLF transcription factor, PAR bZIP family member
decreases expression
EXP
bromobenzene results in decreased expression of HLF mRNA
CTD
PMID:32479839
NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
G
Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
decreases expression
EXP
bromobenzene results in decreased expression of HMGCS1 mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
decreases expression
EXP
bromobenzene results in decreased expression of HMGCS2 mRNA
CTD
PMID:12628495
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
G
Hmgn5
high mobility group nucleosome binding domain 5
increases expression
EXP
bromobenzene results in increased expression of HMGN5 mRNA
CTD
PMID:32479839
NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441
G
Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO EXP
bromobenzene results in increased expression of HMOX1 protein [bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HMOX1 mRNA bromobenzene results in increased expression of HMOX1 mRNA; bromobenzene results in increased expression of HMOX1 protein
CTD
PMID:3343248 PMID:12628495 PMID:15056800 PMID:15976192 PMID:18078705 PMID:24190904 PMID:32479839 More...
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnf4a
hepatocyte nuclear factor 4, alpha
increases expression
EXP
bromobenzene results in increased expression of HNF4A mRNA
CTD
PMID:32479839
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
G
Homer2
homer scaffold protein 2
increases expression
EXP
bromobenzene results in increased expression of HOMER2 mRNA
CTD
PMID:12628495
NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
G
Hpdl
4-hydroxyphenylpyruvate dioxygenase-like
increases expression
EXP
bromobenzene results in increased expression of HPDL mRNA
CTD
PMID:32479839
NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233
G
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
decreases expression
EXP
bromobenzene results in decreased expression of HSD11B2 mRNA
CTD
PMID:32479839
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
G
Hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
decreases expression
EXP
bromobenzene results in decreased expression of HSD17B2 mRNA
CTD
PMID:32479839
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
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Hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
decreases expression
EXP
bromobenzene results in decreased expression of HSD17B7 mRNA
CTD
PMID:32479839
NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
ISO
bromobenzene results in increased expression of HSPA1A mRNA; bromobenzene results in increased expression of HSPA1A protein
CTD
PMID:8917683
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
EXP
bromobenzene results in increased expression of HSPA1B mRNA
CTD
PMID:32479839
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
G
Hspa4l
heat shock protein family A (Hsp70) member 4 like
decreases expression
EXP
bromobenzene results in decreased expression of HSPA4L mRNA
CTD
PMID:32479839
NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
G
Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression affects binding increases expression
EXP
bromobenzene results in decreased expression of HSPA5 mRNA bromobenzene metabolite binds to HSPA5 protein bromobenzene results in increased expression of HSPA5 mRNA
CTD
PMID:12018992 PMID:12628495 PMID:15056800
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Hspa8
heat shock protein family A (Hsp70) member 8
affects binding
EXP
bromobenzene metabolite binds to HSPA8 protein
CTD
PMID:17305373
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Htatip2
HIV-1 Tat interactive protein 2
increases expression
EXP
bromobenzene results in increased expression of HTATIP2 mRNA
CTD
PMID:32479839
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
G
Icam1
intercellular adhesion molecule 1
increases expression
ISO
bromobenzene analog results in increased expression of ICAM1 protein
CTD
PMID:19427879
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Id2
inhibitor of DNA binding 2
increases expression
EXP
bromobenzene results in increased expression of ID2 mRNA
CTD
PMID:32479839
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
G
Idh1
isocitrate dehydrogenase (NADP(+)) 1
affects binding
EXP
bromobenzene metabolite binds to IDH1 protein
CTD
PMID:17305373
NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
G
Idi1
isopentenyl-diphosphate delta isomerase 1
decreases expression
EXP
bromobenzene results in decreased expression of IDI1 mRNA
CTD
PMID:32479839
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
G
Ier3
immediate early response 3
increases expression
EXP
bromobenzene results in increased expression of IER3 mRNA
CTD
PMID:32479839
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
G
Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
decreases expression
EXP
bromobenzene results in decreased expression of ISG12(B) mRNA
CTD
PMID:12628495
NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
G
Ifrd1
interferon-related developmental regulator 1
increases expression
EXP
bromobenzene results in increased expression of IFRD1 mRNA
CTD
PMID:32479839
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
G
Ift122
intraflagellar transport 122
increases expression
EXP
bromobenzene results in increased expression of IFT122 mRNA
CTD
PMID:32479839
NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458
G
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
decreases expression
EXP
bromobenzene results in decreased expression of IGDCC3 mRNA
CTD
PMID:32479839
NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959
G
Igf1
insulin-like growth factor 1
decreases expression
EXP
bromobenzene results in decreased expression of IGF1 mRNA
CTD
PMID:12628495
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igfbp2
insulin-like growth factor binding protein 2
increases expression
EXP
bromobenzene results in increased expression of IGFBP2 mRNA
CTD
PMID:32479839
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
G
Igsf7 l1
immunoglobulin superfamily, member 7 like 1
decreases expression
EXP
bromobenzene results in decreased expression of IGSF7 L1 mRNA
CTD
PMID:32479839
NCBI chr10:100,174,955...100,182,713
Ensembl chr10:100,156,238...100,182,647
G
Ihh
Indian hedgehog signaling molecule
decreases expression
EXP
bromobenzene results in decreased expression of IHH mRNA
CTD
PMID:32479839
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
G
Ikzf4
IKAROS family zinc finger 4
increases expression
EXP
bromobenzene results in increased expression of IKZF4 mRNA
CTD
PMID:32479839
NCBI chr 7:1,063,283...1,102,940
Ensembl chr 7:1,056,890...1,084,341
G
Il13ra2
interleukin 13 receptor subunit alpha 2
decreases expression
EXP
bromobenzene results in decreased expression of IL13RA2 mRNA
CTD
PMID:32479839
NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381
G
Il17rb
interleukin 17 receptor B
increases expression
EXP
bromobenzene results in increased expression of IL17RB mRNA
CTD
PMID:32479839
NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
G
Il6r
interleukin 6 receptor
increases expression
EXP
bromobenzene results in increased expression of IL6R mRNA
CTD
PMID:32479839
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
G
Inhba
inhibin subunit beta A
decreases expression
EXP
bromobenzene results in decreased expression of INHBA mRNA
CTD
PMID:32479839
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
G
Inka1
inka box actin regulator 1
decreases expression
EXP
bromobenzene results in decreased expression of INKA1 mRNA
CTD
PMID:32479839
NCBI chr 8:108,674,263...108,675,953
Ensembl chr 8:108,674,263...108,675,953
G
Inpp4b
inositol polyphosphate-4-phosphatase type II B
increases expression
EXP
bromobenzene results in increased expression of INPP4B mRNA
CTD
PMID:32479839
NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
G
Insc
INSC, spindle orientation adaptor protein
increases expression
EXP
bromobenzene results in increased expression of INSC mRNA
CTD
PMID:32479839
NCBI chr 1:168,993,032...169,100,438
Ensembl chr 1:168,993,032...169,100,433
G
Insig1
insulin induced gene 1
decreases expression
EXP
bromobenzene results in decreased expression of INSIG1 mRNA
CTD
PMID:32479839
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
G
Insig2
insulin induced gene 2
increases expression
EXP
bromobenzene results in increased expression of INSIG2 mRNA
CTD
PMID:32479839
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
G
Ip6k2
inositol hexakisphosphate kinase 2
affects expression
EXP
bromobenzene affects the expression of IP6K2 mRNA
CTD
PMID:32479839
NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
G
Iqgap3
IQ motif containing GTPase activating protein 3
increases expression
EXP
bromobenzene results in increased expression of IQGAP3 mRNA
CTD
PMID:32479839
NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956
G
Irf2bp2
interferon regulatory factor 2 binding protein 2
increases expression
EXP
bromobenzene results in increased expression of IRF2BP2 mRNA
CTD
PMID:32479839
NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642
G
Irs2
insulin receptor substrate 2
increases expression
EXP
bromobenzene results in increased expression of IRS2 mRNA
CTD
PMID:32479839
NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
G
Irx1
iroquois homeobox 1
decreases expression
EXP
bromobenzene results in decreased expression of IRX1 mRNA
CTD
PMID:32479839
NCBI chr 1:31,294,615...31,300,444
Ensembl chr 1:31,294,615...31,300,444
G
Itih4
inter-alpha-trypsin inhibitor heavy chain 4
decreases expression
EXP
bromobenzene results in decreased expression of ITIH4 mRNA
CTD
PMID:12628495
NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
G
Jakmip1
janus kinase and microtubule interacting protein 1
increases expression
EXP
bromobenzene results in increased expression of JAKMIP1 mRNA
CTD
PMID:32479839
NCBI chr14:73,646,299...73,766,830
Ensembl chr14:73,632,428...73,713,993
G
Jakmip2
janus kinase and microtubule interacting protein 2
increases expression
EXP
bromobenzene results in increased expression of JAKMIP2 mRNA
CTD
PMID:32479839
NCBI chr18:35,532,552...35,747,938
Ensembl chr18:35,532,552...35,747,775
G
Kcnf1
potassium voltage-gated channel modifier subfamily F member 1
increases expression
EXP
bromobenzene results in increased expression of KCNF1 mRNA
CTD
PMID:32479839
NCBI chr 6:39,962,301...39,964,979
Ensembl chr 6:39,962,307...39,964,979
G
Kcnj15
potassium inwardly-rectifying channel, subfamily J, member 15
decreases expression
EXP
bromobenzene results in decreased expression of KCNJ15 mRNA
CTD
PMID:32479839
NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952
G
Kcnk1
potassium two pore domain channel subfamily K member 1
increases expression
EXP
bromobenzene results in increased expression of KCNK1 mRNA
CTD
PMID:32479839
NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
G
Kcnk2
potassium two pore domain channel subfamily K member 2
increases expression
EXP
bromobenzene results in increased expression of KCNK2 mRNA
CTD
PMID:32479839
NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
G
Kcnt1
potassium sodium-activated channel subfamily T member 1
increases expression
EXP
bromobenzene results in increased expression of KCNT1 mRNA
CTD
PMID:32479839
NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667
G
Kctd15
potassium channel tetramerization domain containing 15
increases expression
EXP
bromobenzene results in increased expression of KCTD15 mRNA
CTD
PMID:32479839
NCBI chr 1:87,258,658...87,271,979
Ensembl chr 1:87,258,658...87,273,497
G
Kif23
kinesin family member 23
increases expression
EXP
bromobenzene results in increased expression of KIF23 mRNA
CTD
PMID:32479839
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
G
Kif6
kinesin family member 6
increases expression
EXP
bromobenzene results in increased expression of KIF6 mRNA
CTD
PMID:32479839
NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
G
Kir3dl1
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
increases expression
EXP
bromobenzene results in increased expression of KIR3DL1 mRNA
CTD
PMID:32479839
NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050
G
Kirrel3
kirre like nephrin family adhesion molecule 3
decreases expression
EXP
bromobenzene results in decreased expression of KIRREL3 mRNA
CTD
PMID:32479839
NCBI chr 8:32,865,779...33,407,555
Ensembl chr 8:32,862,776...33,405,676
G
Klc3
kinesin light chain 3
affects binding
EXP
bromobenzene metabolite binds to KLC3 protein
CTD
PMID:17305373
NCBI chr 1:79,045,842...79,055,809
Ensembl chr 1:79,045,844...79,055,416
G
Klf10
KLF transcription factor 10
increases expression
EXP
bromobenzene results in increased expression of KLF10 mRNA
CTD
PMID:32479839
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
G
Klf12
KLF transcription factor 12
decreases expression
EXP
bromobenzene results in decreased expression of KLF12 mRNA
CTD
PMID:32479839
NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
G
Klf15
KLF transcription factor 15
increases expression
EXP
bromobenzene results in increased expression of KLF15 mRNA
CTD
PMID:32479839
NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
G
Klf9
KLF transcription factor 9
increases expression
EXP
bromobenzene results in increased expression of KLF9 mRNA
CTD
PMID:32479839
NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
G
Krt23
keratin 23
increases expression
EXP
bromobenzene results in increased expression of KRT23 mRNA
CTD
PMID:32479839
NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983
G
Lad1
ladinin 1
increases expression
EXP
bromobenzene results in increased expression of LAD1 mRNA
CTD
PMID:32479839
NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967
G
Lap3
leucine aminopeptidase 3
decreases expression
EXP
bromobenzene results in decreased expression of LAP3 mRNA
CTD
PMID:15056800
NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
G
Ldhb
lactate dehydrogenase B
decreases expression
EXP
bromobenzene results in decreased expression of LDHB mRNA
CTD
PMID:15056800
NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
G
Ldlr
low density lipoprotein receptor
decreases expression
EXP
bromobenzene results in decreased expression of LDLR mRNA
CTD
PMID:32479839
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
G
Lgi2
leucine-rich repeat LGI family, member 2
increases expression
EXP
bromobenzene results in increased expression of LGI2 mRNA
CTD
PMID:32479839
NCBI chr14:58,415,965...58,443,450
Ensembl chr14:58,415,965...58,443,407
G
Lgr5
leucine rich repeat containing G protein coupled receptor 5
decreases expression
EXP
bromobenzene results in decreased expression of LGR5 mRNA
CTD
PMID:32479839
NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
G
Lgsn
lengsin, lens protein with glutamine synthetase domain
decreases expression
EXP
bromobenzene results in decreased expression of LGSN mRNA
CTD
PMID:32479839
NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907
G
Lonp1
lon peptidase 1, mitochondrial
increases expression
EXP
bromobenzene results in increased expression of LONP1 mRNA
CTD
PMID:15056800
NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
G
Lonrf3
LON peptidase N-terminal domain and ring finger 3
increases expression
EXP
bromobenzene results in increased expression of LONRF3 mRNA
CTD
PMID:32479839
NCBI chr X:115,565,214...115,603,886
Ensembl chr X:115,565,267...115,598,809
G
Lox
lysyl oxidase
increases expression
EXP
bromobenzene results in increased expression of LOX mRNA
CTD
PMID:32479839
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Lpar3
lysophosphatidic acid receptor 3
increases expression
EXP
bromobenzene results in increased expression of LPAR3 mRNA
CTD
PMID:32479839
NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357
G
Lpin1
lipin 1
increases expression
EXP
bromobenzene results in increased expression of LPIN1 mRNA
CTD
PMID:32479839
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
G
Lrrc4
leucine rich repeat containing 4
increases expression
EXP
bromobenzene results in increased expression of LRRC4 mRNA
CTD
PMID:32479839
NCBI chr 4:57,433,518...57,437,114
Ensembl chr 4:57,433,428...57,437,911
G
Lrrc58
leucine rich repeat containing 58
increases expression
EXP
bromobenzene results in increased expression of LRRC58 mRNA
CTD
PMID:32479839
NCBI chr11:62,850,507...62,862,829
Ensembl chr11:62,847,562...62,862,829
G
Lst1
leukocyte specific transcript 1
decreases expression
EXP
bromobenzene results in decreased expression of LST1 mRNA
CTD
PMID:32479839
NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
G
Ltbp2
latent transforming growth factor beta binding protein 2
decreases expression
EXP
bromobenzene results in decreased expression of LTBP2 mRNA
CTD
PMID:32479839
NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
G
Lypd1
Ly6/Plaur domain containing 1
increases expression
EXP
bromobenzene results in increased expression of LYPD1 mRNA
CTD
PMID:32479839
NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493
G
Lypd3
Ly6/Plaur domain containing 3
affects expression
EXP
bromobenzene affects the expression of LYPD3 mRNA
CTD
PMID:32479839
NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
G
Mab21l3
mab-21 like 3
increases expression
EXP
bromobenzene results in increased expression of MAB21L3 mRNA
CTD
PMID:32479839
NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652
G
Mafb
MAF bZIP transcription factor B
increases expression
EXP
bromobenzene results in increased expression of MAFB mRNA
CTD
PMID:32479839
NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
G
Maff
MAF bZIP transcription factor F
increases expression
EXP
bromobenzene results in increased expression of MAFF mRNA
CTD
PMID:32479839
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
G
Magi3
membrane associated guanylate kinase, WW and PDZ domain containing 3
decreases expression
EXP
bromobenzene results in decreased expression of MAGI3 mRNA
CTD
PMID:32479839
NCBI chr 2:191,514,726...191,717,048
Ensembl chr 2:191,518,506...191,716,735
G
Mal
mal, T-cell differentiation protein
decreases expression
EXP
bromobenzene results in decreased expression of MAL mRNA
CTD
PMID:32479839
NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
G
Map3k5
mitogen-activated protein kinase kinase kinase 5
increases expression
EXP
bromobenzene results in increased expression of MAP3K5 mRNA
CTD
PMID:32479839
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
G
Map3k6
mitogen-activated protein kinase kinase kinase 6
increases expression
EXP
bromobenzene results in increased expression of MAP3K6 mRNA
CTD
PMID:32479839
NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212
G
Map3k9
mitogen-activated protein kinase kinase kinase 9
increases expression
EXP
bromobenzene results in increased expression of MAP3K9 mRNA
CTD
PMID:32479839
NCBI chr 6:101,423,754...101,488,822
Ensembl chr 6:101,430,292...101,488,822
G
Mapk14
mitogen activated protein kinase 14
increases phosphorylation
ISO
bromobenzene analog results in increased phosphorylation of MAPK14 protein
CTD
PMID:19427879
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
G
Mapkapk3
MAPK activated protein kinase 3
increases expression
EXP
bromobenzene results in increased expression of MAPKAPK3 mRNA
CTD
PMID:32479839
NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
G
Marchf1
membrane associated ring-CH-type finger 1
increases expression
EXP
bromobenzene results in increased expression of MARCHF1 mRNA
CTD
PMID:32479839
NCBI chr16:23,255,551...24,114,290
Ensembl chr16:23,258,799...24,114,277
G
Mat1a
methionine adenosyltransferase 1A
increases expression
EXP
bromobenzene results in increased expression of MAT1A mRNA
CTD
PMID:32479839
NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
G
Mb
myoglobin
decreases expression
EXP
bromobenzene results in decreased expression of MB mRNA
CTD
PMID:32479839
NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
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Mcf2
MCF.2 cell line derived transforming sequence
increases expression
EXP
bromobenzene results in increased expression of MCF2 mRNA
CTD
PMID:32479839
NCBI chr X:138,414,077...138,514,828
Ensembl chr X:138,409,256...138,514,446
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Mcm10
minichromosome maintenance 10 replication initiation factor
increases expression
EXP
bromobenzene results in increased expression of MCM10 mRNA
CTD
PMID:32479839
NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
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Mcm3
minichromosome maintenance complex component 3
decreases expression
EXP
bromobenzene results in decreased expression of MCM3 mRNA
CTD
PMID:32479839
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
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Mcm6
minichromosome maintenance complex component 6
decreases expression
EXP
bromobenzene results in decreased expression of MCM6 mRNA
CTD
PMID:32479839
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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Mcoln2
mucolipin TRP cation channel 2
increases expression
EXP
bromobenzene results in increased expression of MCOLN2 mRNA
CTD
PMID:32479839
NCBI chr 2:235,053,816...235,102,703
Ensembl chr 2:235,053,816...235,102,702
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Mcub
mitochondrial calcium uniporter dominant negative subunit beta
increases expression
EXP
bromobenzene results in increased expression of MCUB mRNA
CTD
PMID:32479839
NCBI chr 2:218,479,301...218,549,594
Ensembl chr 2:218,479,301...218,549,593
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Mdh1b
malate dehydrogenase 1B
decreases expression
EXP
bromobenzene results in decreased expression of MDH1B mRNA
CTD
PMID:32479839
NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933
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Meiob
meiosis specific with OB-fold
decreases expression
EXP
bromobenzene results in decreased expression of MEIOB mRNA
CTD
PMID:32479839
NCBI chr10:13,833,170...13,865,684
Ensembl chr10:13,833,750...13,865,046
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Metap2
methionyl aminopeptidase 2
increases expression
EXP
bromobenzene results in increased expression of METAP2 mRNA
CTD
PMID:12628495
NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
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Mex3b
mex-3 RNA binding family member B
increases expression
EXP
bromobenzene results in increased expression of MEX3B mRNA
CTD
PMID:32479839
NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354
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Mfsd2a
MFSD2 lysolipid transporter A, lysophospholipid
increases expression
EXP
bromobenzene results in increased expression of MFSD2A mRNA
CTD
PMID:32479839
NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
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Mgat4b
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
decreases expression
EXP
bromobenzene results in decreased expression of MGAT4B mRNA
CTD
PMID:32479839
NCBI chr10:34,548,918...34,559,229
Ensembl chr10:34,549,433...34,559,229
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Mid1ip1
MID1 interacting protein 1
decreases expression
EXP
bromobenzene results in decreased expression of MID1IP1 mRNA
CTD
PMID:32479839
NCBI chr X:12,060,993...12,063,318
Ensembl chr X:12,060,883...12,065,774
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Mif
macrophage migration inhibitory factor
affects binding
EXP
bromobenzene metabolite binds to MIF protein
CTD
PMID:17305373
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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Mipol1
mirror-image polydactyly 1
increases expression
EXP
bromobenzene results in increased expression of MIPOL1 mRNA
CTD
PMID:32479839
NCBI chr 6:74,755,293...75,090,403
Ensembl chr 6:74,755,395...75,086,811
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Mknk2
MAPK interacting serine/threonine kinase 2
decreases expression
EXP
bromobenzene results in decreased expression of MKNK2 mRNA
CTD
PMID:32479839
NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
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Mmd2
monocyte to macrophage differentiation-associated 2
decreases expression
EXP
bromobenzene results in decreased expression of MMD2 mRNA
CTD
PMID:32479839
NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773
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Mocos
molybdenum cofactor sulfurase
increases expression
EXP
bromobenzene results in increased expression of MOCOS mRNA
CTD
PMID:32479839
NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187
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Mprip
myosin phosphatase Rho interacting protein
increases expression
EXP
bromobenzene results in increased expression of MPRIP mRNA
CTD
PMID:15056800
NCBI chr10:44,453,949...44,573,843
Ensembl chr10:44,453,929...44,569,118
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Mrc1
mannose receptor, C type 1
increases expression
EXP
bromobenzene results in increased expression of MRC1 mRNA
CTD
PMID:32479839
NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
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Mroh9
maestro heat-like repeat family member 9
increases expression
EXP
bromobenzene results in increased expression of MROH9 mRNA
CTD
PMID:32479839
NCBI chr13:75,387,800...75,443,118
Ensembl chr13:75,387,746...75,443,092
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Ms4a1
membrane spanning 4-domains A1
decreases expression
EXP
bromobenzene results in decreased expression of MS4A1 mRNA
CTD
PMID:32479839
NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512
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Ms4a6bl1
membrane-spanning 4-domains, subfamily A, member 6B-like 1
increases expression
EXP
bromobenzene results in increased expression of MS4A6BL1 mRNA
CTD
PMID:32479839
NCBI chr 1:208,243,561...208,255,400
Ensembl chr 1:208,243,559...208,257,340
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Msantd1
Myb/SANT DNA binding domain containing 1
increases expression
EXP
bromobenzene results in increased expression of MSANTD1 mRNA
CTD
PMID:32479839
NCBI chr14:75,832,368...75,845,687
Ensembl chr14:75,835,380...75,844,183
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Msmo1
methylsterol monooxygenase 1
decreases expression
EXP
bromobenzene results in decreased expression of MSMO1 mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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Mst1r
macrophage stimulating 1 receptor
decreases expression
EXP
bromobenzene results in decreased expression of MST1R mRNA
CTD
PMID:32479839
NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455
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Mt1
metallothionein 1
increases expression
EXP
bromobenzene results in increased expression of MT1 mRNA
CTD
PMID:32479839
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt2A
metallothionein 2A
increases expression
EXP
bromobenzene results in increased expression of MT2A mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mt4
metallothionein 4
increases expression
EXP
bromobenzene results in increased expression of MT4 mRNA
CTD
PMID:15056800
NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909
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Mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
increases expression
EXP
bromobenzene results in increased expression of MTHFD2 mRNA
CTD
PMID:32479839
NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
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Mthfr
methylenetetrahydrofolate reductase
decreases expression
EXP
bromobenzene results in decreased expression of MTHFR mRNA
CTD
PMID:32479839
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Mtss1
MTSS I-BAR domain containing 1
increases expression
EXP
bromobenzene results in increased expression of MTSS1 mRNA
CTD
PMID:32479839
NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
G
Muc13
mucin 13, cell surface associated
decreases expression
EXP
bromobenzene results in decreased expression of MUC13 mRNA
CTD
PMID:32479839
NCBI chr11:66,957,208...66,980,264
Ensembl chr11:66,960,595...66,984,727
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Mug1
murinoglobulin 1
decreases expression
EXP
bromobenzene results in decreased expression of MUG1 mRNA
CTD
PMID:12628495
NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
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Mug2
murinoglobulin 2
decreases expression
EXP
bromobenzene results in decreased expression of PZP mRNA
CTD
PMID:12628495
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
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Mvd
mevalonate diphosphate decarboxylase
decreases expression
EXP
bromobenzene results in decreased expression of MVD mRNA
CTD
PMID:32479839
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Mvk
mevalonate kinase
decreases expression
EXP
bromobenzene results in decreased expression of MVK mRNA
CTD
PMID:32479839
NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
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Mx1
MX dynamin like GTPase 1
decreases expression
EXP
bromobenzene results in decreased expression of MX1 mRNA
CTD
PMID:32479839
NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
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Mybl1
MYB proto-oncogene like 1
increases expression
EXP
bromobenzene results in increased expression of MYBL1 mRNA
CTD
PMID:32479839
NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
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Myc
MYC proto-oncogene, bHLH transcription factor
increases expression
EXP
bromobenzene results in increased expression of MYC mRNA
CTD
PMID:32479839
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myh7b
myosin heavy chain 7B
increases expression
EXP
bromobenzene results in increased expression of MYH7B mRNA
CTD
PMID:32479839
NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084
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Mylk3
myosin light chain kinase 3
decreases expression
EXP
bromobenzene results in decreased expression of MYLK3 mRNA
CTD
PMID:32479839
NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954
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Myo9b
myosin IXb
decreases expression
EXP
bromobenzene results in decreased expression of MYO9B mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126
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Myom2
myomesin 2
increases expression
EXP
bromobenzene results in increased expression of MYOM2 mRNA
CTD
PMID:32479839
NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772
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Nampt
nicotinamide phosphoribosyltransferase
increases expression
EXP
bromobenzene results in increased expression of NAMPT mRNA
CTD
PMID:32479839
NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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Nat8f5
N-acetyltransferase 8 (GCN5-related) family member 5
decreases expression
EXP
bromobenzene results in decreased expression of NAT8F5 mRNA
CTD
PMID:32479839
NCBI chr 4:118,260,323...118,285,038
Ensembl chr 4:118,260,252...118,285,704
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Ncald
neurocalcin delta
increases expression
EXP
bromobenzene results in increased expression of NCALD mRNA
CTD
PMID:32479839
NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496
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Nceh1
neutral cholesterol ester hydrolase 1
increases expression
EXP
bromobenzene results in increased expression of NCEH1 mRNA
CTD
PMID:32479839
NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
G
Ndst1
N-deacetylase and N-sulfotransferase 1
decreases expression
EXP
bromobenzene results in decreased expression of NDST1 mRNA
CTD
PMID:32479839
NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
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Neil2
nei-like DNA glycosylase 2
increases expression
EXP
bromobenzene results in increased expression of NEIL2 mRNA
CTD
PMID:32479839
NCBI chr15:37,444,676...37,454,863
Ensembl chr15:37,445,381...37,454,863
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Nes
nestin
increases expression
EXP
bromobenzene results in increased expression of NES mRNA
CTD
PMID:12628495
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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Nfe2
nuclear factor, erythroid 2
decreases expression
EXP
bromobenzene results in decreased expression of NFE2 mRNA
CTD
PMID:32479839
NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases localization increases expression
ISO
bromobenzene results in increased localization of NFE2L2 protein bromobenzene analog results in increased expression of NFE2L2 protein
CTD
PMID:18078705 PMID:19427879
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nherf1
NHERF family PDZ scaffold protein 1
decreases expression
EXP
bromobenzene results in decreased expression of NHERF1 mRNA
CTD
PMID:32479839
NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
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Nim1k
NIM1 serine/threonine protein kinase
increases expression
EXP
bromobenzene results in increased expression of NIM1K mRNA
CTD
PMID:32479839
NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762
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Nkx1-2
NK1 homeobox 2
increases expression
EXP
bromobenzene results in increased expression of NKX1-2 mRNA
CTD
PMID:32479839
NCBI chr 1:187,386,370...187,391,252
Ensembl chr 1:187,388,711...187,391,149
G
Nmrk2
nicotinamide riboside kinase 2
increases expression
EXP
bromobenzene results in increased expression of NMRK2 mRNA
CTD
PMID:32479839
NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922
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Noct
nocturnin
increases expression
EXP
bromobenzene results in increased expression of NOCT mRNA
CTD
PMID:32479839
NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
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Nol8
nucleolar protein 8
increases expression
EXP
bromobenzene results in increased expression of NOL8 mRNA
CTD
PMID:32479839
NCBI chr17:14,990,394...15,013,784
Ensembl chr17:14,990,417...15,013,848
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Nox4
NADPH oxidase 4
decreases expression
EXP
bromobenzene results in decreased expression of NOX4 mRNA
CTD
PMID:15976192
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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Npas2
neuronal PAS domain protein 2
increases expression
EXP
bromobenzene results in increased expression of NPAS2 mRNA
CTD
PMID:32479839
NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
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Npm1
nucleophosmin 1
increases expression
EXP
bromobenzene results in increased expression of NPM1 mRNA
CTD
PMID:12628495
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
G
Npr3
natriuretic peptide receptor 3
decreases expression
EXP
bromobenzene results in decreased expression of NPR3 mRNA
CTD
PMID:32479839
NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
G
Npsr1
neuropeptide S receptor 1
decreases expression
EXP
bromobenzene results in decreased expression of NPSR1 mRNA
CTD
PMID:32479839
NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558
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Nqo1
NAD(P)H quinone dehydrogenase 1
affects response to substance increases expression
ISO EXP
NQO1 protein affects the susceptibility to bromobenzene bromobenzene results in increased expression of NQO1 mRNA
CTD
PMID:10092053 PMID:15976192 PMID:17538237 PMID:32479839
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nrbf2
nuclear receptor binding factor 2
increases expression
EXP
bromobenzene results in increased expression of NRBF2 mRNA
CTD
PMID:32479839
NCBI chr20:21,308,555...21,326,881
Ensembl chr20:21,308,576...21,326,818
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Nrep
neuronal regeneration related protein
decreases expression
EXP
bromobenzene results in decreased expression of NREP mRNA
CTD
PMID:32479839
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Ntrk1
neurotrophic receptor tyrosine kinase 1
increases expression
EXP
bromobenzene results in increased expression of NTRK1 mRNA
CTD
PMID:32479839
NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
G
Nudt4
nudix hydrolase 4
increases expression
EXP
bromobenzene results in increased expression of NUDT4 mRNA
CTD
PMID:32479839
NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615
G
Nupr1
nuclear protein 1, transcriptional regulator
decreases expression
EXP
bromobenzene results in decreased expression of NUPR1 mRNA
CTD
PMID:15056800
NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
G
Nxph3
neurexophilin 3
decreases expression
EXP
bromobenzene results in decreased expression of NXPH3 mRNA
CTD
PMID:32479839
NCBI chr10:80,456,283...80,459,949
Ensembl chr10:80,455,429...80,462,415
G
Odf2l
outer dense fiber of sperm tails 2-like
increases expression
EXP
bromobenzene results in increased expression of ODF2L mRNA
CTD
PMID:32479839
NCBI chr 2:234,036,049...234,072,751
Ensembl chr 2:234,033,652...234,072,747
G
Olr35
olfactory receptor 35
increases expression
EXP
bromobenzene results in increased expression of OLR35 mRNA
CTD
PMID:32479839
NCBI chr 1:153,994,678...154,043,281
Ensembl chr 1:154,041,306...154,043,257
G
Omd
osteomodulin
increases expression
EXP
bromobenzene results in increased expression of OMD mRNA
CTD
PMID:32479839
NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441
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Orc1
origin recognition complex, subunit 1
increases expression
EXP
bromobenzene results in increased expression of ORC1 mRNA
CTD
PMID:32479839
NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
G
Orm1
orosomucoid 1
increases expression
EXP
bromobenzene results in increased expression of ORM1 mRNA
CTD
PMID:16036859
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
G
Osbp2
oxysterol binding protein 2
increases expression
EXP
bromobenzene results in increased expression of OSBP2 mRNA
CTD
PMID:32479839
NCBI chr14:78,585,088...78,746,785
Ensembl chr14:78,585,089...78,746,786
G
Osbpl8
oxysterol binding protein-like 8
decreases expression
EXP
bromobenzene results in decreased expression of OSBPL8 mRNA
CTD
PMID:32479839
NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
G
Osgin1
oxidative stress induced growth inhibitor 1
increases expression
EXP
bromobenzene results in increased expression of OSGIN1 mRNA
CTD
PMID:32479839
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
G
Otud6b
OTU deubiquitinase 6B
increases expression
EXP
bromobenzene results in increased expression of OTUD6B mRNA
CTD
PMID:32479839
NCBI chr 5:28,181,992...28,214,486
Ensembl chr 5:28,023,594...28,214,334
G
Oxct1
3-oxoacid CoA transferase 1
decreases expression
EXP
bromobenzene results in decreased expression of OXCT1 mRNA
CTD
PMID:15056800
NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
G
P2ry12
purinergic receptor P2Y12
increases expression
EXP
bromobenzene results in increased expression of P2RY12 mRNA
CTD
PMID:32479839
NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
G
P4hb
prolyl 4-hydroxylase subunit beta
affects binding
EXP
bromobenzene metabolite binds to P4HB protein
CTD
PMID:12018992
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
G
Padi1
peptidyl arginine deiminase 1
increases expression
EXP
bromobenzene results in increased expression of PADI1 mRNA
CTD
PMID:32479839
NCBI chr 5:153,119,566...153,152,034
Ensembl chr 5:153,119,566...153,152,034
G
Park7
Parkinsonism associated deglycase
affects binding
EXP
bromobenzene metabolite binds to PARK7 protein
CTD
PMID:17305373
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
G
Parp14
poly (ADP-ribose) polymerase family, member 14
decreases expression
EXP
bromobenzene results in decreased expression of PARP14 mRNA
CTD
PMID:32479839
NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916
G
Pax3
paired box 3
decreases expression
EXP
bromobenzene results in decreased expression of PAX3 mRNA
CTD
PMID:32479839
NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
G
Pax8
paired box 8
increases expression
EXP
bromobenzene results in increased expression of PAX8 mRNA
CTD
PMID:32479839
NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
G
Pcdh8
protocadherin 8
increases expression
EXP
bromobenzene results in increased expression of PCDH8 mRNA
CTD
PMID:32479839
NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872
G
Pcdhb3
protocadherin beta 3
decreases expression
EXP
bromobenzene results in decreased expression of PCDHB3 mRNA
CTD
PMID:32479839
NCBI chr18:29,011,667...29,014,221
Ensembl chr18:29,011,816...29,015,188
G
Pcp4
Purkinje cell protein 4
increases expression
EXP
bromobenzene results in increased expression of PCP4 mRNA
CTD
PMID:32479839
NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
G
Pcsk1
proprotein convertase subtilisin/kexin type 1
increases expression
EXP
bromobenzene results in increased expression of PCSK1 mRNA
CTD
PMID:32479839
NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
G
Pcsk9
proprotein convertase subtilisin/kexin type 9
decreases expression
EXP
bromobenzene results in decreased expression of PCSK9 mRNA
CTD
PMID:32479839
NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
G
Pcyt1a
phosphate cytidylyltransferase 1A, choline
increases expression
EXP
bromobenzene results in increased expression of PCYT1A mRNA
CTD
PMID:32479839
NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
G
Pde6c
phosphodiesterase 6C
decreases expression
EXP
bromobenzene results in decreased expression of PDE6C mRNA
CTD
PMID:32479839
NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315
G
Pdgfrb
platelet derived growth factor receptor beta
increases expression
EXP
bromobenzene results in increased expression of PDGFRB mRNA
CTD
PMID:32479839
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
G
Pdia3
protein disulfide isomerase family A, member 3
affects binding
EXP
bromobenzene metabolite binds to PDIA3 protein
CTD
PMID:12018992
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
G
Pdia5
protein disulfide isomerase family A, member 5
decreases expression
EXP
bromobenzene results in decreased expression of PDIA5 mRNA
CTD
PMID:32479839
NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
G
Pdia6
protein disulfide isomerase family A, member 6
affects binding
EXP
bromobenzene metabolite binds to PDIA6 protein
CTD
PMID:12018992
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
G
Pdk4
pyruvate dehydrogenase kinase 4
increases expression
EXP
bromobenzene results in increased expression of PDK4 mRNA
CTD
PMID:32479839
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
G
Pebp1
phosphatidylethanolamine binding protein 1
affects binding
EXP
bromobenzene metabolite binds to PEBP1 protein
CTD
PMID:17305373
NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
G
Per1
period circadian regulator 1
increases expression
EXP
bromobenzene results in increased expression of PER1 mRNA
CTD
PMID:32479839
NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
G
Per2
period circadian regulator 2
decreases expression
EXP
bromobenzene results in decreased expression of PER2 mRNA
CTD
PMID:32479839
NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
G
Pex11a
peroxisomal biogenesis factor 11 alpha
increases expression
EXP
bromobenzene results in increased expression of PEX11A mRNA
CTD
PMID:32479839
NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
G
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
increases expression
EXP
bromobenzene results in increased expression of PFKFB1 mRNA
CTD
PMID:32479839
NCBI chr X:19,508,522...19,562,165
Ensembl chr X:19,508,546...19,562,182
G
Pgk1
phosphoglycerate kinase 1
affects binding
EXP
bromobenzene metabolite binds to PGK1 protein
CTD
PMID:17305373
NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
G
Phlda1
pleckstrin homology-like domain, family A, member 1
increases expression
EXP
bromobenzene results in increased expression of PHLDA1 mRNA
CTD
PMID:15976192
NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
G
Pigu
phosphatidylinositol glycan anchor biosynthesis, class U
increases expression
EXP
bromobenzene results in increased expression of PIGU mRNA
CTD
PMID:32479839
NCBI chr 3:143,784,831...143,881,268
Ensembl chr 3:143,784,832...143,880,807
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
decreases expression
EXP
bromobenzene results in decreased expression of PIK3R1 mRNA
CTD
PMID:32479839
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
G
Pim3
Pim-3 proto-oncogene, serine/threonine kinase
increases expression
EXP
bromobenzene results in increased expression of PIM3 mRNA
CTD
PMID:32479839
NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587
G
Pip4p2
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
increases expression
EXP
bromobenzene results in increased expression of PIP4P2 mRNA
CTD
PMID:32479839
NCBI chr 5:28,259,821...28,307,225
Ensembl chr 5:28,259,760...28,307,225
G
Pir
pirin
increases expression
EXP
bromobenzene results in increased expression of PIR mRNA
CTD
PMID:32479839
NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
G
Pklr
pyruvate kinase L/R
decreases expression
EXP
bromobenzene results in decreased expression of PKLR mRNA
CTD
PMID:32479839
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
G
Plekhm3
pleckstrin homology domain containing M3
increases expression
EXP
bromobenzene results in increased expression of PLEKHM3 mRNA
CTD
PMID:32479839
NCBI chr 9:66,166,233...66,325,332
Ensembl chr 9:66,166,321...66,325,294
G
Plin2
perilipin 2
increases expression
EXP
bromobenzene results in increased expression of PLIN2 mRNA
CTD
PMID:32479839
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Plin5
perilipin 5
increases expression
EXP
bromobenzene results in increased expression of PLIN5 mRNA
CTD
PMID:32479839
NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
G
Plk3
polo-like kinase 3
increases expression
EXP
bromobenzene results in increased expression of PLK3 mRNA
CTD
PMID:32479839
NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
G
Plppr1
phospholipid phosphatase related 1
increases expression
EXP
bromobenzene results in increased expression of PLPPR1 mRNA
CTD
PMID:32479839
NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
G
Plppr3
phospholipid phosphatase related 3
decreases expression
EXP
bromobenzene results in decreased expression of PLPPR3 mRNA
CTD
PMID:32479839
NCBI chr 7:9,831,162...9,842,434
Ensembl chr 7:9,831,162...9,845,296
G
Pls1
plastin 1
decreases expression
EXP
bromobenzene results in decreased expression of PLS1 mRNA
CTD
PMID:32479839
NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
G
Plxna2
plexin A2
decreases expression
EXP
bromobenzene results in decreased expression of PLXNA2 mRNA
CTD
PMID:32479839
NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979
G
Pnpla3
patatin-like phospholipase domain containing 3
decreases expression
EXP
bromobenzene results in decreased expression of PNPLA3 mRNA
CTD
PMID:32479839
NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
G
Polg2
DNA polymerase gamma 2, accessory subunit
increases expression
EXP
bromobenzene results in increased expression of POLG2 mRNA
CTD
PMID:32479839
NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008
G
Polq
DNA polymerase theta
increases expression
EXP
bromobenzene results in increased expression of POLQ mRNA
CTD
PMID:32479839
NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
G
Por
cytochrome p450 oxidoreductase
increases expression
EXP
bromobenzene results in increased expression of POR mRNA
CTD
PMID:12628495 PMID:32479839
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Ppargc1a
PPARG coactivator 1 alpha
increases expression
EXP
bromobenzene results in increased expression of PPARGC1A mRNA
CTD
PMID:32479839
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
G
Ppat
phosphoribosyl pyrophosphate amidotransferase
increases expression
EXP
bromobenzene results in increased expression of PPAT mRNA
CTD
PMID:32479839
NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
G
Ppcs
phosphopantothenoylcysteine synthetase
increases expression
EXP
bromobenzene results in increased expression of PPCS mRNA
CTD
PMID:32479839
NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
G
Ppm1k
protein phosphatase, Mg2+/Mn2+ dependent, 1K
increases expression
EXP
bromobenzene results in increased expression of PPM1K mRNA
CTD
PMID:32479839
NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:87,612,204...87,636,152
G
Ppp1r3g
protein phosphatase 1, regulatory subunit 3G
increases expression
EXP
bromobenzene results in increased expression of PPP1R3G mRNA
CTD
PMID:32479839
NCBI chr17:28,874,956...28,878,288
Ensembl chr17:28,876,482...28,877,525
G
Ppp2r1b
protein phosphatase 2 scaffold subunit A beta
increases expression
EXP
bromobenzene results in increased expression of PPP2R1B mRNA
CTD
PMID:32479839
NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
G
Pptc7
protein phosphatase targeting COQ7
increases expression
EXP
bromobenzene results in increased expression of PPTC7 mRNA
CTD
PMID:32479839
NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339
G
Prdx6
peroxiredoxin 6
affects binding
EXP
bromobenzene metabolite binds to PRDX6 protein
CTD
PMID:17305373
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
G
Prickle1
prickle planar cell polarity protein 1
increases expression
EXP
bromobenzene results in increased expression of PRICKLE1 mRNA
CTD
PMID:32479839
NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113
G
Prima1
proline rich membrane anchor 1
decreases expression
EXP
bromobenzene results in decreased expression of PRIMA1 mRNA
CTD
PMID:32479839
NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921
G
Prkag3
protein kinase AMP-activated non-catalytic subunit gamma 3
increases expression
EXP
bromobenzene results in increased expression of PRKAG3 mRNA
CTD
PMID:32479839
NCBI chr 9:76,295,715...76,304,959
Ensembl chr 9:76,295,715...76,304,959
G
Prmt7
protein arginine methyltransferase 7
increases expression
EXP
bromobenzene results in increased expression of PRMT7 mRNA
CTD
PMID:32479839
NCBI chr19:34,110,724...34,161,531
Ensembl chr19:34,110,747...34,162,577
G
Prok1
prokineticin 1
decreases expression
EXP
bromobenzene results in decreased expression of PROK1 mRNA
CTD
PMID:32479839
NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250
G
Prpf3
pre-mRNA processing factor 3
decreases expression
EXP
bromobenzene results in decreased expression of PRPF3 mRNA
CTD
PMID:32479839
NCBI chr 2:183,379,041...183,403,526
Ensembl chr 2:183,378,718...183,403,489
G
Prr30
proline rich 30
increases expression
EXP
bromobenzene results in increased expression of PRR30 mRNA
CTD
PMID:32479839
NCBI chr 6:25,415,069...25,417,582
Ensembl chr 6:25,414,868...25,417,585
G
Prrg4
proline rich and Gla domain 4
decreases expression
EXP
bromobenzene results in decreased expression of PRRG4 mRNA
CTD
PMID:32479839
NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273
G
Prtfdc1
phosphoribosyl transferase domain containing 1
decreases expression
EXP
bromobenzene results in decreased expression of PRTFDC1 mRNA
CTD
PMID:32479839
NCBI chr17:83,549,608...83,654,517
Ensembl chr17:83,548,803...83,655,179
G
Psma1
proteasome 20S subunit alpha 1
increases expression
EXP
bromobenzene results in increased expression of PSMA1 mRNA
CTD
PMID:12628495
NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
G
Psma3
proteasome 20S subunit alpha 3
increases expression
EXP
bromobenzene results in increased expression of PSMA3 mRNA
CTD
PMID:12628495
NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
G
Psmb3
proteasome 20S subunit beta 3
increases expression
EXP
bromobenzene results in increased expression of PSMB3 mRNA
CTD
PMID:12628495
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
G
Psmb5
proteasome 20S subunit beta 5
increases expression
EXP
bromobenzene results in increased expression of PSMB5 mRNA
CTD
PMID:12628495
NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
G
Psmc3
proteasome 26S subunit, ATPase 3
affects binding
EXP
bromobenzene metabolite binds to PSMC3 protein
CTD
PMID:17305373
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
G
Psmc4
proteasome 26S subunit, ATPase 4
affects binding
EXP
bromobenzene metabolite binds to PSMC4 protein
CTD
PMID:17305373
NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
G
Psmc5
proteasome 26S subunit, ATPase 5
increases expression
EXP
bromobenzene results in increased expression of PSMC5 mRNA
CTD
PMID:12628495
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
G
Psmd5
proteasome 26S subunit, non-ATPase 5
increases expression
EXP
bromobenzene results in increased expression of PSMD5 mRNA
CTD
PMID:12628495
NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
G
Psme1
proteasome activator subunit 1
affects binding
EXP
bromobenzene metabolite binds to PSME1 protein
CTD
PMID:17305373
NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
G
Ptgds
prostaglandin D2 synthase
increases expression
EXP
bromobenzene results in increased expression of PTGDS mRNA
CTD
PMID:32479839
NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP
[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of PTGS2 mRNA
CTD
PMID:24190904
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptma
prothymosin alpha
increases expression
EXP
bromobenzene results in increased expression of PTMA mRNA
CTD
PMID:12628495
NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
G
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
increases expression
EXP
bromobenzene results in increased expression of PTPN14 mRNA
CTD
PMID:32479839
NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088
G
Ptprcap
protein tyrosine phosphatase, receptor type, C-associated protein
decreases expression
EXP
bromobenzene results in decreased expression of PTPRCAP mRNA
CTD
PMID:32479839
NCBI chr 1:201,449,133...201,451,293
Ensembl chr 1:201,449,113...201,451,288
G
Ptprg
protein tyrosine phosphatase, receptor type, G
increases expression
EXP
bromobenzene results in increased expression of PTPRG mRNA
CTD
PMID:32479839
NCBI chr15:12,871,706...13,552,186
Ensembl chr15:12,871,721...13,554,094
G
Ptpru
protein tyrosine phosphatase, receptor type, U
increases expression
EXP
bromobenzene results in increased expression of PTPRU mRNA
CTD
PMID:32479839
NCBI chr 5:143,950,542...144,024,791
Ensembl chr 5:143,950,965...144,024,768
G
Pvr
PVR cell adhesion molecule
increases expression
EXP
bromobenzene results in increased expression of PVR mRNA
CTD
PMID:32479839
NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
G
Pygm
glycogen phosphorylase, muscle associated
decreases expression
EXP
bromobenzene results in decreased expression of PYGM mRNA
CTD
PMID:32479839
NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
G
Qrfpr
pyroglutamylated RFamide peptide receptor
increases expression
EXP
bromobenzene results in increased expression of QRFPR mRNA
CTD
PMID:32479839
NCBI chr 2:119,053,083...119,096,864
Ensembl chr 2:119,053,511...119,096,792
G
Rab23
RAB23, member RAS oncogene family
increases expression
EXP
bromobenzene results in increased expression of RAB23 mRNA
CTD
PMID:32479839
NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
G
Rab30
RAB30, member RAS oncogene family
increases expression
EXP
bromobenzene results in increased expression of RAB30 mRNA
CTD
PMID:32479839
NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
G
Rab9b
RAB9B, member RAS oncogene family
decreases expression
EXP
bromobenzene results in decreased expression of RAB9B mRNA
CTD
PMID:32479839
NCBI chr X:100,220,897...100,231,591
Ensembl chr X:100,220,894...100,231,701
G
Rad51
RAD51 recombinase
decreases expression
EXP
bromobenzene results in decreased expression of RAD51 mRNA
CTD
PMID:32479839
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
G
Rad54l2
RAD54 like 2
decreases expression
EXP
bromobenzene results in decreased expression of RAD54L2 mRNA
CTD
PMID:32479839
NCBI chr 8:107,324,945...107,427,033
Ensembl chr 8:107,327,420...107,427,106
G
Ran
RAN, member RAS oncogene family
increases expression
EXP
bromobenzene results in increased expression of RAN mRNA
CTD
PMID:12628495
NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
G
Rasd1
ras related dexamethasone induced 1
increases expression
EXP
bromobenzene results in increased expression of RASD1 mRNA
CTD
PMID:32479839
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
G
Rasl10a
RAS-like, family 10, member A
decreases expression
EXP
bromobenzene results in decreased expression of RASL10A mRNA
CTD
PMID:32479839
NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468
G
Rec8
REC8 meiotic recombination protein
increases expression
EXP
bromobenzene results in increased expression of REC8 mRNA
CTD
PMID:32479839
NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326
G
Reg4
regenerating family member 4
decreases expression
EXP
bromobenzene results in decreased expression of REG4 mRNA
CTD
PMID:32479839
NCBI chr 2:185,818,946...185,833,252
Ensembl chr 2:185,821,210...185,833,353
G
RGD1562699
RGD1562699
decreases expression
EXP
bromobenzene results in decreased expression of RGD1562699 mRNA
CTD
PMID:32479839
NCBI chr18:57,826,815...57,831,464
Ensembl chr18:57,827,117...57,827,989
G
Rgma
repulsive guidance molecule BMP co-receptor a
increases expression
EXP
bromobenzene results in increased expression of RGMA mRNA
CTD
PMID:32479839
NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918
G
Rgn
regucalcin
affects binding
EXP
bromobenzene metabolite binds to RGN protein
CTD
PMID:17305373
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
G
Rgs1
regulator of G-protein signaling 1
increases expression
EXP
bromobenzene results in increased expression of RGS1 mRNA
CTD
PMID:32479839
NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984
G
Rgs20
regulator of G-protein signaling 20
increases expression
EXP
bromobenzene results in increased expression of RGS20 mRNA
CTD
PMID:32479839
NCBI chr 5:14,484,436...14,614,317
Ensembl chr 5:14,534,775...14,614,084
G
Rgs3
regulator of G-protein signaling 3
decreases expression
EXP
bromobenzene results in decreased expression of RGS3 mRNA
CTD
PMID:32479839
NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894
G
Rgs9bp
regulator of G protein signaling 9 binding protein
decreases expression
EXP
bromobenzene results in decreased expression of RGS9BP mRNA
CTD
PMID:32479839
NCBI chr 1:88,249,438...88,250,151
Ensembl chr 1:88,249,438...88,250,151
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Rhbdd2
rhomboid domain containing 2
increases expression
EXP
bromobenzene results in increased expression of RHBDD2 mRNA
CTD
PMID:32479839
NCBI chr12:21,043,605...21,054,305
Ensembl chr12:21,043,608...21,054,289
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Rida
reactive intermediate imine deaminase A homolog
affects binding
EXP
bromobenzene metabolite binds to RIDA protein
CTD
PMID:17305373
NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
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Rlim
ring finger protein, LIM domain interacting
increases expression
EXP
bromobenzene results in increased expression of RLIM mRNA
CTD
PMID:32479839
NCBI chr X:68,983,259...69,004,368
Ensembl chr X:68,988,375...69,004,271
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Rnase11
ribonuclease A family member 11
affects expression
EXP
bromobenzene affects the expression of RNASE11 mRNA
CTD
PMID:32479839
NCBI chr15:24,268,206...24,270,192
Ensembl chr15:24,268,207...24,270,192
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Rnf151
ring finger protein 151
increases expression
EXP
bromobenzene results in increased expression of RNF151 mRNA
CTD
PMID:32479839
NCBI chr10:13,742,682...13,747,192
Ensembl chr10:13,742,682...13,745,000
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Ropn1
rhophilin associated tail protein 1
increases expression
EXP
bromobenzene results in increased expression of ROPN1 mRNA
CTD
PMID:32479839
NCBI chr11:66,097,854...66,127,148
Ensembl chr11:66,097,856...66,127,148
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Rpl15
ribosomal protein L15
increases expression
EXP
bromobenzene results in increased expression of RPL15 mRNA
CTD
PMID:12628495
NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
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Rpl22
ribosomal protein L22
increases expression
EXP
bromobenzene results in increased expression of RPL22 mRNA
CTD
PMID:15056800
NCBI chr 5:162,835,241...162,843,394
Ensembl chr 5:162,833,740...162,843,368 Ensembl chr 7:162,833,740...162,843,368 Ensembl chr 4:162,833,740...162,843,368
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Rpl27a
ribosomal protein L27A
increases expression
EXP
bromobenzene results in increased expression of RPL27A mRNA
CTD
PMID:16036859
NCBI chr 1:163,539,732...163,542,771
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Rpl35
ribosomal protein L35
increases expression decreases expression
EXP
bromobenzene results in increased expression of RPL35 mRNA bromobenzene results in decreased expression of RPL35 mRNA
CTD
PMID:12628495 PMID:15056800
NCBI chr 3:22,753,255...22,756,217
Ensembl chr 3:22,753,253...22,756,243
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Rpl6
ribosomal protein L6
increases expression
EXP
bromobenzene results in increased expression of RPL6 mRNA
CTD
PMID:12628495
NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
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Rprm
reprimo, TP53 dependent G2 arrest mediator homolog
increases expression
EXP
bromobenzene results in increased expression of RPRM mRNA
CTD
PMID:32479839
NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998
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Rps11
ribosomal protein S11
increases expression
EXP
bromobenzene results in increased expression of RPS11 mRNA
CTD
PMID:12628495
NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874
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Rps2
ribosomal protein S2
increases expression
EXP
bromobenzene results in increased expression of RPS2 mRNA
CTD
PMID:12628495
NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
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Rps26
ribosomal protein S26
increases expression
EXP
bromobenzene results in increased expression of RPS26 mRNA
CTD
PMID:12628495
NCBI chr 7:1,057,332...1,058,882
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Rps26l1
ribosomal protein S26 like 1
increases expression
EXP
bromobenzene results in increased expression of RPS26L1 mRNA
CTD
PMID:32479839
NCBI chr 7:62,981,687...62,982,757
Ensembl chr 7:62,981,946...62,982,326
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Rps3a
ribosomal protein S3a
increases expression
EXP
bromobenzene results in increased expression of RPS3A mRNA
CTD
PMID:12628495
NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
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Rps6kb1
ribosomal protein S6 kinase B1
increases expression
EXP
bromobenzene results in increased expression of RPS6KB1 mRNA
CTD
PMID:15056800
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Rps8
ribosomal protein S8
increases expression
EXP
bromobenzene results in increased expression of RPS8 mRNA
CTD
PMID:12628495
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
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Rrp9
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
decreases expression
EXP
bromobenzene results in decreased expression of RRP9 mRNA
CTD
PMID:12628495
NCBI chr 8:107,116,411...107,126,123
Ensembl chr 8:107,117,471...107,126,123
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Rsrp1
arginine and serine rich protein 1
decreases expression
EXP
bromobenzene results in decreased expression of RSRP1 mRNA
CTD
PMID:32479839
NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523
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RT1-CE10
RT1 class I, locus CE10
increases expression
EXP
bromobenzene results in increased expression of RT1-CE10 mRNA
CTD
PMID:32479839
NCBI chr20:3,377,284...3,380,301
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RT1-CE3
RT1 class I, locus CE3
increases expression
EXP
bromobenzene results in increased expression of RT1-CE3 mRNA
CTD
PMID:32479839
NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081
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RT1-M2
RT1 class Ib, locus M2
increases expression
EXP
bromobenzene results in increased expression of RT1-M2 mRNA
CTD
PMID:32479839
NCBI chr20:978,918...981,510
Ensembl chr20:978,935...981,723
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RT1-M6-2
RT1 class I, locus M6, gene 2
increases expression
EXP
bromobenzene results in increased expression of RT1-M6-2 mRNA
CTD
PMID:32479839
NCBI chr20:1,583,267...1,587,099
Ensembl chr20:1,583,299...1,586,215
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RT1-N1
RT1 class Ib, locus N1
increases expression decreases expression
EXP
bromobenzene results in increased expression of RT1-N1 mRNA bromobenzene results in decreased expression of RT1-N1 mRNA
CTD
PMID:12628495 PMID:15056800
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RT1-S2
RT1 class Ib, locus S2
increases expression
EXP
bromobenzene results in increased expression of RT1-S2 mRNA
CTD
PMID:32479839
NCBI chr20:2,650,233...2,651,654
Ensembl chr20:2,649,964...2,652,027
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Rtn4rl2
reticulon 4 receptor-like 2
decreases expression
EXP
bromobenzene results in decreased expression of RTN4RL2 mRNA
CTD
PMID:32479839
NCBI chr 3:69,954,557...69,971,108
Ensembl chr 3:69,955,169...69,971,488
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Sacs
sacsin molecular chaperone
increases expression
EXP
bromobenzene results in increased expression of SACS mRNA
CTD
PMID:32479839
NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335
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Samd4a
sterile alpha motif domain containing 4A
increases expression
EXP
bromobenzene results in increased expression of SAMD4A mRNA
CTD
PMID:32479839
NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380
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Sapcd2
suppressor APC domain containing 2
increases expression
EXP
bromobenzene results in increased expression of SAPCD2 mRNA
CTD
PMID:32479839
NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546
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Sash1
SAM and SH3 domain containing 1
increases expression
EXP
bromobenzene results in increased expression of SASH1 mRNA
CTD
PMID:32479839
NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870
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Saxo2
stabilizer of axonemal microtubules 2
increases expression
EXP
bromobenzene results in increased expression of SAXO2 mRNA
CTD
PMID:32479839
NCBI chr 1:136,596,445...136,638,444
Ensembl chr 1:136,623,493...136,638,454
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Sbds
Sbds, ribosome maturation factor
decreases expression
EXP
bromobenzene results in decreased expression of SBDS mRNA
CTD
PMID:12628495
NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649
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Sc5d
sterol-C5-desaturase
decreases expression
EXP
bromobenzene results in decreased expression of SC5D mRNA
CTD
PMID:32479839
NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
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Scd
stearoyl-CoA desaturase
decreases expression increases expression
EXP
bromobenzene results in decreased expression of SCD1 mRNA bromobenzene results in increased expression of SCD mRNA
CTD
PMID:15976192 PMID:32479839
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Scn4b
sodium voltage-gated channel beta subunit 4
increases expression
EXP
bromobenzene results in increased expression of SCN4B mRNA
CTD
PMID:32479839
NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292
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Scnn1a
sodium channel epithelial 1 subunit alpha
increases expression
EXP
bromobenzene results in increased expression of SCNN1A mRNA
CTD
PMID:32479839
NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
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Sdc4
syndecan 4
increases expression
EXP
bromobenzene results in increased expression of SDC4 mRNA
CTD
PMID:32479839
NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
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Sds
serine dehydratase
increases expression
EXP
bromobenzene results in increased expression of SDS mRNA
CTD
PMID:32479839
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
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Sebox
SEBOX homeobox
decreases expression
EXP
bromobenzene results in decreased expression of SEBOX mRNA
CTD
PMID:32479839
NCBI chr10:63,399,215...63,400,086
Ensembl chr10:63,399,165...63,400,606
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Selenbp1
selenium binding protein 1
affects binding
EXP
bromobenzene metabolite binds to SELENBP1 protein
CTD
PMID:17305373
NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
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Selenop
selenoprotein P
decreases expression
EXP
bromobenzene results in decreased expression of SELENOP mRNA
CTD
PMID:12628495
NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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Sell
selectin L
decreases expression
EXP
bromobenzene results in decreased expression of SELL mRNA
CTD
PMID:32479839
NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
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Sema6b
semaphorin 6B
increases expression
EXP
bromobenzene results in increased expression of SEMA6B mRNA
CTD
PMID:32479839
NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521
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Sesn2
sestrin 2
increases expression
EXP
bromobenzene results in increased expression of SESN2 mRNA
CTD
PMID:32479839
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Setbp1
SET binding protein 1
increases expression
EXP
bromobenzene results in increased expression of SETBP1 mRNA
CTD
PMID:32479839
NCBI chr18:72,190,542...72,551,272
Ensembl chr18:72,191,035...72,552,556
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Sgk1
serum/glucocorticoid regulated kinase 1
increases expression
EXP
bromobenzene results in increased expression of SGK1 mRNA
CTD
PMID:32479839
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Sgk2
serum/glucocorticoid regulated kinase 2
decreases expression
EXP
bromobenzene results in decreased expression of SGK2 mRNA
CTD
PMID:32479839
NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
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Sh2d4a
SH2 domain containing 4A
decreases expression
EXP
bromobenzene results in decreased expression of SH2D4A mRNA
CTD
PMID:32479839
NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260
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Sh3pxd2b
SH3 and PX domains 2B
increases expression
EXP
bromobenzene results in increased expression of SH3PXD2B mRNA
CTD
PMID:32479839
NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170
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Sidt1
SID1 transmembrane family, member 1
increases expression
EXP
bromobenzene results in increased expression of SIDT1 mRNA
CTD
PMID:32479839
NCBI chr11:56,362,788...56,459,939
Ensembl chr11:56,363,512...56,459,050
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Slamf6
SLAM family member 6
increases expression
EXP
bromobenzene results in increased expression of SLAMF6 mRNA
CTD
PMID:32479839
NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300
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Slc10a2
solute carrier family 10 member 2
decreases expression
EXP
bromobenzene results in decreased expression of SLC10A2 mRNA
CTD
PMID:32479839
NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
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Slc10a6
solute carrier family 10 member 6
increases expression
EXP
bromobenzene results in increased expression of SLC10A6 mRNA
CTD
PMID:32479839
NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037
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Slc11a1
solute carrier family 11 member 1
decreases expression
EXP
bromobenzene results in decreased expression of SLC11A1 mRNA
CTD
PMID:32479839
NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
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Slc13a2
solute carrier family 13 member 2
decreases expression
EXP
bromobenzene results in decreased expression of SLC13A2 mRNA
CTD
PMID:32479839
NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
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Slc13a4
solute carrier family 13 member 4
decreases expression
EXP
bromobenzene results in decreased expression of SLC13A4 mRNA
CTD
PMID:32479839
NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857
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Slc13a5
solute carrier family 13 member 5
increases expression
EXP
bromobenzene results in increased expression of SLC13A5 mRNA
CTD
PMID:32479839
NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945
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Slc15a4
solute carrier family 15 member 4
increases expression
EXP
bromobenzene results in increased expression of SLC15A4 mRNA
CTD
PMID:12628495
NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480
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Slc16a5
solute carrier family 16 member 5
increases expression
EXP
bromobenzene results in increased expression of SLC16A5 mRNA
CTD
PMID:32479839
NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338
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Slc17a9
solute carrier family 17 member 9
decreases expression
EXP
bromobenzene results in decreased expression of SLC17A9 mRNA
CTD
PMID:32479839
NCBI chr 3:167,839,246...167,857,462
Ensembl chr 3:167,839,385...167,855,985
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Slc19a2
solute carrier family 19 member 2
decreases expression
EXP
bromobenzene results in decreased expression of SLC19A2 mRNA
CTD
PMID:32479839
NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
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Slc1a3
solute carrier family 1 member 3
affects expression
EXP
bromobenzene affects the expression of SLC1A3 mRNA
CTD
PMID:32479839
NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
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Slc1a4
solute carrier family 1 member 4
increases expression
EXP
bromobenzene results in increased expression of SLC1A4 mRNA
CTD
PMID:32479839
NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
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Slc22a5
solute carrier family 22 member 5
increases expression
EXP
bromobenzene results in increased expression of SLC22A5 mRNA
CTD
PMID:32479839
NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
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Slc25a15
solute carrier family 25 member 15
increases expression
EXP
bromobenzene results in increased expression of SLC25A15 mRNA
CTD
PMID:32479839
NCBI chr16:69,631,581...69,654,869
Ensembl chr16:69,634,414...69,653,010
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Slc25a25
solute carrier family 25 member 25
increases expression
EXP
bromobenzene results in increased expression of SLC25A25 mRNA
CTD
PMID:32479839
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
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Slc25a27
solute carrier family 25, member 27
increases expression
EXP
bromobenzene results in increased expression of SLC25A27 mRNA
CTD
PMID:32479839
NCBI chr 9:17,306,898...17,333,942
Ensembl chr 9:17,307,023...17,332,731
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Slc25a29
solute carrier family 25 member 29
increases expression
EXP
bromobenzene results in increased expression of SLC25A29 mRNA
CTD
PMID:32479839
NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940
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Slc25a30
solute carrier family 25, member 30
decreases expression
EXP
bromobenzene results in decreased expression of SLC25A30 mRNA
CTD
PMID:32479839
NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
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Slc25a32
solute carrier family 25 member 32
increases expression
EXP
bromobenzene results in increased expression of SLC25A32 mRNA
CTD
PMID:32479839
NCBI chr 7:70,142,958...70,160,726
Ensembl chr 7:70,142,964...70,160,770
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Slc29a4
solute carrier family 29 member 4
decreases expression
EXP
bromobenzene results in decreased expression of SLC29A4 mRNA
CTD
PMID:32479839
NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834
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Slc2a1
solute carrier family 2 member 1
increases expression
EXP
bromobenzene results in increased expression of SLC2A1 mRNA
CTD
PMID:32479839
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc34a2
solute carrier family 34 member 2
decreases expression
EXP
bromobenzene results in decreased expression of SLC34A2 mRNA
CTD
PMID:32479839
NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
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Slc35g1
solute carrier family 35, member G1
increases expression
EXP
bromobenzene results in increased expression of SLC35G1 mRNA
CTD
PMID:32479839
NCBI chr 1:236,163,593...236,172,115
Ensembl chr 1:236,163,175...236,170,262
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Slc38a2
solute carrier family 38, member 2
increases expression
EXP
bromobenzene results in increased expression of SLC38A2 mRNA
CTD
PMID:32479839
NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
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Slc43a1
solute carrier family 43 member 1
decreases expression
EXP
bromobenzene results in decreased expression of SLC43A1 mRNA
CTD
PMID:32479839
NCBI chr 3:69,920,586...69,946,768
Ensembl chr 3:69,920,649...69,946,768
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Slc44a3
solute carrier family 44, member 3
increases expression
EXP
bromobenzene results in increased expression of SLC44A3 mRNA
CTD
PMID:32479839
NCBI chr 2:209,552,138...209,628,182
Ensembl chr 2:209,552,144...209,629,044
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Slc45a3
solute carrier family 45, member 3
decreases expression
EXP
bromobenzene results in decreased expression of SLC45A3 mRNA
CTD
PMID:32479839
NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588
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Slc4a11
solute carrier family 4 member 11
decreases expression
EXP
bromobenzene results in decreased expression of SLC4A11 mRNA
CTD
PMID:32479839
NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674
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Slc4a4
solute carrier family 4 member 4
increases expression
EXP
bromobenzene results in increased expression of SLC4A4 mRNA
CTD
PMID:32479839
NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
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Slc4a5
solute carrier family 4 member 5
increases expression
EXP
bromobenzene results in increased expression of SLC4A5 mRNA
CTD
PMID:32479839
NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323
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Slc51a
solute carrier family 51 member A
increases expression
EXP
bromobenzene results in increased expression of SLC51A mRNA
CTD
PMID:32479839
NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485
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Slc5a8
solute carrier family 5 member 8
increases expression
EXP
bromobenzene results in increased expression of SLC5A8 mRNA
CTD
PMID:32479839
NCBI chr 7:23,272,891...23,313,811
Ensembl chr 7:23,272,427...23,314,642
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Slc6a14
solute carrier family 6 member 14
increases expression
EXP
bromobenzene results in increased expression of SLC6A14 mRNA
CTD
PMID:32479839
NCBI chr X:112,314,643...112,375,412
Ensembl chr X:112,314,691...112,375,096
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Slc6a6
solute carrier family 6 member 6
increases expression
EXP
bromobenzene results in increased expression of SLC6A6 mRNA
CTD
PMID:32479839
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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Slc7a1
solute carrier family 7 member 1
increases expression
EXP
bromobenzene results in increased expression of SLC7A1 mRNA
CTD
PMID:32479839
NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
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Slc7a11
solute carrier family 7 member 11
increases expression
EXP
bromobenzene results in increased expression of SLC7A11 mRNA
CTD
PMID:32479839
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slco1a4
solute carrier organic anion transporter family, member 1a4
decreases expression
EXP
bromobenzene results in decreased expression of SLCO1A4 mRNA
CTD
PMID:15976192 PMID:32479839
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
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Slco1c1
solute carrier organic anion transporter family, member 1c1
increases expression
EXP
bromobenzene results in increased expression of SLCO1C1 mRNA
CTD
PMID:32479839
NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289
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Slit1
slit guidance ligand 1
increases expression
EXP
bromobenzene results in increased expression of SLIT1 mRNA
CTD
PMID:32479839
NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
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Slitrk1
SLIT and NTRK-like family, member 1
increases expression
EXP
bromobenzene results in increased expression of SLITRK1 mRNA
CTD
PMID:32479839
NCBI chr15:85,723,252...85,727,290
Ensembl chr15:85,724,475...85,727,509
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Smox
spermine oxidase
increases expression
EXP
bromobenzene results in increased expression of SMOX mRNA
CTD
PMID:32479839
NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
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Sntb1
syntrophin, beta 1
increases expression
EXP
bromobenzene results in increased expression of SNTB1 mRNA
CTD
PMID:32479839
NCBI chr 7:87,060,926...87,329,315
Ensembl chr 7:87,060,926...87,329,315
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Sod1
superoxide dismutase 1
affects binding
EXP
bromobenzene metabolite binds to SOD1 protein
CTD
PMID:17305373
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sord
sorbitol dehydrogenase
increases activity
EXP
bromobenzene results in increased activity of SORD protein
CTD
PMID:3012827
NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
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Spdya
speedy/RINGO cell cycle regulator family member A
decreases expression
EXP
bromobenzene results in decreased expression of SPDYA mRNA
CTD
PMID:32479839
NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850
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Spib
Spi-B transcription factor
decreases expression
EXP
bromobenzene results in decreased expression of SPIB mRNA
CTD
PMID:32479839
NCBI chr 1:95,018,939...95,024,804
Ensembl chr 1:95,018,947...95,024,780
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Spring1
SREBF pathway regulator in golgi 1
increases expression
EXP
bromobenzene results in increased expression of SPRING1 mRNA
CTD
PMID:32479839
NCBI chr12:38,306,227...38,329,175
Ensembl chr12:38,297,837...38,329,138
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Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
increases expression
EXP
bromobenzene results in increased expression of SPSB1 mRNA
CTD
PMID:32479839
NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
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Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
increases expression
EXP
bromobenzene results in increased expression of SPSB4 mRNA
CTD
PMID:32479839
NCBI chr 8:97,536,519...97,609,757
Ensembl chr 8:97,536,520...97,609,787
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Sqle
squalene epoxidase
decreases expression
EXP
bromobenzene results in decreased expression of SQLE mRNA
CTD
PMID:32479839
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
EXP
bromobenzene results in decreased expression of SREBF1 mRNA
CTD
PMID:32479839
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srp68
signal recognition particle 68
increases expression
EXP
bromobenzene results in increased expression of SRP68 mRNA
CTD
PMID:32479839
NCBI chr10:101,481,213...101,508,035
Ensembl chr10:101,481,212...101,508,035
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Sstr3
somatostatin receptor 3
increases expression
EXP
bromobenzene results in increased expression of SSTR3 mRNA
CTD
PMID:32479839
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
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St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
increases expression
EXP
bromobenzene results in increased expression of ST8SIA1 mRNA
CTD
PMID:32479839
NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
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Stac3
SH3 and cysteine rich domain 3
decreases expression
EXP
bromobenzene results in decreased expression of STAC3 mRNA
CTD
PMID:32479839
NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
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Stard4
StAR-related lipid transfer domain containing 4
decreases expression
EXP
bromobenzene results in decreased expression of STARD4 mRNA
CTD
PMID:32479839
NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
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Stc1
stanniocalcin 1
decreases expression
EXP
bromobenzene results in decreased expression of STC1 mRNA
CTD
PMID:32479839
NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
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Steap2
STEAP2 metalloreductase
increases expression
EXP
bromobenzene results in increased expression of STEAP2 mRNA
CTD
PMID:32479839
NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
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Stoml3
stomatin like 3
increases expression
EXP
bromobenzene results in increased expression of STOML3 mRNA
CTD
PMID:32479839
NCBI chr 2:137,572,691...137,582,402
Ensembl chr 2:137,572,691...137,590,681
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Stxbp5l
syntaxin binding protein 5L
increases expression
EXP
bromobenzene results in increased expression of STXBP5L mRNA
CTD
PMID:32479839
NCBI chr11:63,334,667...63,654,270
Ensembl chr11:63,334,667...63,657,014
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Sult1b1
sulfotransferase family 1B member 1
affects binding
EXP
bromobenzene metabolite binds to SULT1B1 protein
CTD
PMID:17305373
NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
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Sult1c3
sulfotransferase family 1C member 3
decreases expression
EXP
bromobenzene results in decreased expression of SULT1C1 mRNA
CTD
PMID:15976192
NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
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Svop
SV2 related protein
increases expression
EXP
bromobenzene results in increased expression of SVOP mRNA
CTD
PMID:32479839
NCBI chr12:42,530,991...42,589,381
Ensembl chr12:42,531,032...42,590,572
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Synj2
synaptojanin 2
decreases expression
EXP
bromobenzene results in decreased expression of SYNJ2 mRNA
CTD
PMID:12628495
NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687
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Synpr
synaptoporin
decreases expression
EXP
bromobenzene results in decreased expression of SYNPR mRNA
CTD
PMID:32479839
NCBI chr15:11,573,373...11,900,255
Ensembl chr15:11,574,231...11,900,243
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Sypl1
synaptophysin-like 1
increases expression
EXP
bromobenzene results in increased expression of SYPL1 mRNA
CTD
PMID:32479839
NCBI chr 6:49,565,111...49,585,205
Ensembl chr 6:49,565,154...49,585,330
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Syt2
synaptotagmin 2
decreases expression
EXP
bromobenzene results in decreased expression of SYT2 mRNA
CTD
PMID:32479839
NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
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Taf9b
TATA-box binding protein associated factor 9b
increases expression
EXP
bromobenzene results in increased expression of TAF9B mRNA
CTD
PMID:12628495
NCBI chr X:71,289,290...71,300,142
Ensembl chr X:71,289,290...71,300,604
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Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
increases expression
EXP
bromobenzene results in increased expression of TANC1 mRNA
CTD
PMID:32479839
NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627
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Tat
tyrosine aminotransferase
increases expression
EXP
bromobenzene results in increased expression of TAT mRNA
CTD
PMID:32479839
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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Tbx3
T-box transcription factor 3
increases expression
EXP
bromobenzene results in increased expression of TBX3 mRNA
CTD
PMID:32479839
NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
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Tcea3
transcription elongation factor A3
decreases expression
EXP
bromobenzene results in decreased expression of TCEA3 mRNA
CTD
PMID:32479839
NCBI chr 5:148,476,941...148,509,452
Ensembl chr 5:148,476,941...148,509,448
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Tcim
transcriptional and immune response regulator
increases expression
EXP
bromobenzene results in increased expression of TCIM mRNA
CTD
PMID:32479839
NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581
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Tdrd1
tudor domain containing 1
increases expression
EXP
bromobenzene results in increased expression of TDRD1 mRNA
CTD
PMID:32479839
NCBI chr 1:255,871,939...255,919,222
Ensembl chr 1:255,875,887...255,915,871
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Tekt4
tektin 4
increases expression
EXP
bromobenzene results in increased expression of TEKT4 mRNA
CTD
PMID:32479839
NCBI chr10:14,487,760...14,492,936
Ensembl chr10:14,487,760...14,492,936
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Tenm2
teneurin transmembrane protein 2
decreases expression
EXP
bromobenzene results in decreased expression of TENM2 mRNA
CTD
PMID:32479839
NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597
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Tex36
testis expressed 36
increases expression
EXP
bromobenzene results in increased expression of TEX36 mRNA
CTD
PMID:32479839
NCBI chr 1:188,390,062...188,404,448
Ensembl chr 1:188,390,064...188,404,377
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Tex52
testis expressed 52
increases expression
EXP
bromobenzene results in increased expression of TEX52 mRNA
CTD
PMID:32479839
NCBI chr 4:161,651,232...161,663,250
Ensembl chr 4:161,638,816...161,660,540
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Tf
transferrin
decreases expression
EXP
bromobenzene results in decreased expression of TF mRNA
CTD
PMID:12628495
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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Tfcp2
transcription factor CP2
increases expression
EXP
bromobenzene results in increased expression of TFCP2 mRNA
CTD
PMID:32479839
NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:131,616,785...131,658,939
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Tg
thyroglobulin
decreases expression
EXP
bromobenzene results in decreased expression of TG mRNA
CTD
PMID:32479839
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
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Thbs4
thrombospondin 4
increases expression
EXP
bromobenzene results in increased expression of THBS4 mRNA
CTD
PMID:32479839
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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Thra
thyroid hormone receptor alpha
decreases expression
EXP
bromobenzene results in decreased expression of THRA mRNA
CTD
PMID:15976192
NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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Thrsp
thyroid hormone responsive
decreases expression
EXP
bromobenzene results in decreased expression of THRSP mRNA
CTD
PMID:32479839
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Thsd7b
thrombospondin type 1 domain containing 7B
increases expression
EXP
bromobenzene results in increased expression of THSD7B mRNA
CTD
PMID:32479839
NCBI chr13:40,768,567...41,667,262
Ensembl chr13:40,768,570...41,666,501
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Timeless
timeless circadian regulator
decreases expression
EXP
bromobenzene results in decreased expression of TIMELESS mRNA
CTD
PMID:32479839
NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
EXP
bromobenzene results in increased expression of TIMP1 mRNA
CTD
PMID:12628495 PMID:15056800
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Tlr5
toll-like receptor 5
increases expression
EXP
bromobenzene results in increased expression of TLR5 mRNA
CTD
PMID:32479839
NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738
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Tmem179
transmembrane protein 179
increases expression
EXP
bromobenzene results in increased expression of TMEM179 mRNA
CTD
PMID:32479839
NCBI chr 6:131,569,289...131,580,413
Ensembl chr 6:131,569,290...131,580,305
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Tmem252
transmembrane protein 252
increases expression
EXP
bromobenzene results in increased expression of TMEM252 mRNA
CTD
PMID:32479839
NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943
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Tmem26
transmembrane protein 26
increases expression
EXP
bromobenzene results in increased expression of TMEM26 mRNA
CTD
PMID:32479839
NCBI chr20:19,820,768...19,872,561
Ensembl chr20:19,822,975...19,872,023
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Tmem30b
transmembrane protein 30B
increases expression
EXP
bromobenzene results in increased expression of TMEM30B mRNA
CTD
PMID:32479839
NCBI chr 6:92,251,626...92,254,702
Ensembl chr 6:92,249,790...92,254,842
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Tmprss13
transmembrane serine protease 13
increases expression
EXP
bromobenzene results in increased expression of TMPRSS13 mRNA
CTD
PMID:32479839
NCBI chr 8:45,625,759...45,653,943
Ensembl chr 8:45,625,626...45,653,938
G
Tmsb10
thymosin, beta 10
decreases expression
EXP
bromobenzene results in decreased expression of TMSB10 mRNA
CTD
PMID:12628495
NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
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Tnfaip2
TNF alpha induced protein 2
decreases expression
EXP
bromobenzene results in decreased expression of TNFAIP2 mRNA
CTD
PMID:32479839
NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
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Tnfaip8l3
TNF alpha induced protein 8 like 3
decreases expression
EXP
bromobenzene results in decreased expression of TNFAIP8L3 mRNA
CTD
PMID:32479839
NCBI chr 8:54,413,503...54,455,512
Ensembl chr 8:54,414,457...54,500,079
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Tnfrsf11a
TNF receptor superfamily member 11A
increases expression
EXP
bromobenzene results in increased expression of TNFRSF11A mRNA
CTD
PMID:32479839
NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
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Tnfrsf4
TNF receptor superfamily member 4
increases expression
EXP
bromobenzene results in increased expression of TNFRSF4 mRNA
CTD
PMID:32479839
NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
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Tnnc2
troponin C2, fast skeletal type
increases expression
EXP
bromobenzene results in increased expression of TNNC2 mRNA
CTD
PMID:32479839
NCBI chr 3:153,513,272...153,516,033
Ensembl chr 3:153,513,271...153,516,029
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Tnrc6a
trinucleotide repeat containing adaptor 6A
increases expression
EXP
bromobenzene results in increased expression of TNRC6A mRNA
CTD
PMID:32479839
NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
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Togaram2
TOG array regulator of axonemal microtubules 2
decreases expression
EXP
bromobenzene results in decreased expression of TOGARAM2 mRNA
CTD
PMID:32479839
NCBI chr 6:23,770,979...23,828,884
Ensembl chr 6:23,771,052...23,828,499
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Tom1l2
target of myb1 like 2 membrane trafficking protein
increases expression
EXP
bromobenzene results in increased expression of TOM1L2 mRNA
CTD
PMID:32479839
NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,036,035...45,158,032
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Tonsl
tonsoku-like, DNA repair protein
decreases expression
EXP
bromobenzene results in decreased expression of TONSL mRNA
CTD
PMID:32479839
NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750
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Tor3a
torsin family 3, member A
increases expression
EXP
bromobenzene results in increased expression of TOR3A mRNA
CTD
PMID:32479839
NCBI chr13:68,769,893...68,798,738
Ensembl chr13:68,769,605...68,798,475
G
Tpi1
triosephosphate isomerase 1
affects binding
EXP
bromobenzene metabolite binds to TPI1 protein
CTD
PMID:17305373
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
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Tpm1
tropomyosin 1
affects binding
EXP
bromobenzene metabolite binds to TPM1 protein
CTD
PMID:17305373
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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Trib3
tribbles pseudokinase 3
increases expression
EXP
bromobenzene results in increased expression of TRIB3 mRNA
CTD
PMID:32479839
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Trim15
tripartite motif containing 15
decreases expression
EXP
bromobenzene results in decreased expression of TRIM15 mRNA
CTD
PMID:32479839
NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249
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Trim24
tripartite motif-containing 24
increases expression
EXP
bromobenzene results in increased expression of TRIM24 mRNA
CTD
PMID:32479839
NCBI chr 4:66,567,342...66,692,029
Ensembl chr 4:66,566,686...66,717,241
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Trim36
tripartite motif-containing 36
increases expression
EXP
bromobenzene results in increased expression of TRIM36 mRNA
CTD
PMID:32479839
NCBI chr18:38,859,604...38,912,859
Ensembl chr18:38,861,018...38,912,859
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Trim43a
tripartite motif-containing 43A
increases expression
EXP
bromobenzene results in increased expression of TRIM43A mRNA
CTD
PMID:32479839
NCBI chr 8:89,562,568...89,568,716
Ensembl chr 8:89,562,568...89,568,716
G
Trim45
tripartite motif-containing 45
decreases expression
EXP
bromobenzene results in decreased expression of TRIM45 mRNA
CTD
PMID:32479839
NCBI chr 2:188,349,979...188,359,205
Ensembl chr 2:188,349,744...188,359,204
G
Trim47
tripartite motif-containing 47
decreases expression
EXP
bromobenzene results in decreased expression of TRIM47 mRNA
CTD
PMID:32479839
NCBI chr10:101,337,573...101,342,044
Ensembl chr10:101,337,573...101,342,044
G
Trpm3
transient receptor potential cation channel, subfamily M, member 3
decreases expression
EXP
bromobenzene results in decreased expression of TRPM3 mRNA
CTD
PMID:32479839
NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
G
Tsc22d1
TSC22 domain family, member 1
decreases expression
EXP
bromobenzene results in decreased expression of TSC22D1 mRNA
CTD
PMID:15056800 PMID:32479839
NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
G
Tshr
thyroid stimulating hormone receptor
decreases expression increases expression
EXP
bromobenzene results in decreased expression of TSHR mRNA bromobenzene results in increased expression of TSHR mRNA
CTD
PMID:12628495 PMID:15976192
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
G
Tsku
tsukushi, small leucine rich proteoglycan
increases expression
EXP
bromobenzene results in increased expression of TSKU mRNA
CTD
PMID:32479839
NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
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Ttr
transthyretin
affects binding
EXP
bromobenzene metabolite binds to TTR protein
CTD
PMID:12018992
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
G
Tuba1a
tubulin, alpha 1A
increases expression
EXP
bromobenzene results in increased expression of TUBA1A mRNA
CTD
PMID:16036859
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
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Tubb2a
tubulin, beta 2A class IIa
decreases expression
EXP
bromobenzene results in decreased expression of TUBB2A mRNA
CTD
PMID:32479839
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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Tubb2b
tubulin, beta 2B class IIb
decreases expression
EXP
bromobenzene results in decreased expression of TUBB2B mRNA
CTD
PMID:15056800
NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
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Tubb4b
tubulin, beta 4B class IVb
increases expression
EXP
bromobenzene results in increased expression of TUBB4B mRNA
CTD
PMID:12628495
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
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Txn1
thioredoxin 1
affects binding
EXP
bromobenzene metabolite binds to TXN1 protein
CTD
PMID:17305373
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnrd1
thioredoxin reductase 1
increases expression
EXP
bromobenzene results in increased expression of TXNRD1 mRNA
CTD
PMID:32479839
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Ubd
ubiquitin D
decreases expression
EXP
bromobenzene results in decreased expression of UBD mRNA
CTD
PMID:15056800
NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
G
Ugdh
UDP-glucose 6-dehydrogenase
affects binding
EXP
bromobenzene metabolite binds to UGDH protein
CTD
PMID:17305373
NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
G
Upb1
beta-ureidopropionase 1
affects binding
EXP
bromobenzene metabolite binds to UPB1 protein
CTD
PMID:17305373
NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590
G
Upp2
uridine phosphorylase 2
increases expression
EXP
bromobenzene results in increased expression of UPP2 mRNA
CTD
PMID:32479839
NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417
G
Usp2
ubiquitin specific peptidase 2
increases expression
EXP
bromobenzene results in increased expression of USP2 mRNA
CTD
PMID:32479839
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
G
Usp49
ubiquitin specific peptidase 49
increases expression
EXP
bromobenzene results in increased expression of USP49 mRNA
CTD
PMID:32479839
NCBI chr 9:13,305,640...13,366,132
Ensembl chr 9:13,308,178...13,366,132
G
Vegfd
vascular endothelial growth factor D
increases expression
EXP
bromobenzene results in increased expression of VEGFD mRNA
CTD
PMID:32479839
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
G
Vtn
vitronectin
decreases expression
EXP
bromobenzene results in decreased expression of VTN mRNA
CTD
PMID:12628495
NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
G
Wdr27
WD repeat domain 27
decreases expression
EXP
bromobenzene results in decreased expression of WDR27 mRNA
CTD
PMID:32479839
NCBI chr 1:55,832,240...55,950,457
Ensembl chr 1:55,832,248...55,969,038
G
Wdr91
WD repeat domain 91
increases expression
EXP
bromobenzene results in increased expression of WDR91 mRNA
CTD
PMID:32479839
NCBI chr 4:63,554,364...63,591,733
Ensembl chr 4:63,554,364...63,591,733
G
Wnt4
Wnt family member 4
increases expression
EXP
bromobenzene results in increased expression of WNT4 mRNA
CTD
PMID:32479839
NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
G
Wsb1
WD repeat and SOCS box-containing 1
increases expression
EXP
bromobenzene results in increased expression of WSB1 mRNA
CTD
PMID:32479839
NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
G
Xbp1
X-box binding protein 1
decreases expression
EXP
bromobenzene results in decreased expression of XBP1 mRNA
CTD
PMID:32479839
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
G
Xiap
X-linked inhibitor of apoptosis
decreases expression
EXP
bromobenzene results in decreased expression of XIAP mRNA
CTD
PMID:32479839
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
G
Xpo7
exportin 7
increases expression
EXP
bromobenzene results in increased expression of XPO7 mRNA
CTD
PMID:32479839
NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050
G
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
decreases expression
EXP
bromobenzene results in decreased expression of YWHAQ mRNA
CTD
PMID:15056800
NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
G
Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
decreases expression
EXP
bromobenzene results in decreased expression of YWHAZ mRNA
CTD
PMID:12628495
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
G
Zbp1
Z-DNA binding protein 1
decreases expression
EXP
bromobenzene results in decreased expression of ZBP1 mRNA
CTD
PMID:32479839
NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870
G
Zbtb16
zinc finger and BTB domain containing 16
decreases expression increases expression
EXP
bromobenzene results in decreased expression of ZBTB16 mRNA bromobenzene results in increased expression of ZBTB16 mRNA
CTD
PMID:32479839
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
G
Zbtb7c
zinc finger and BTB domain containing 7C
decreases expression
EXP
bromobenzene results in decreased expression of ZBTB7C mRNA
CTD
PMID:32479839
NCBI chr18:69,441,616...69,765,744
Ensembl chr18:69,441,616...69,765,297
G
Zbtb8b
zinc finger and BTB domain containing 8b
increases expression
EXP
bromobenzene results in increased expression of ZBTB8B mRNA
CTD
PMID:32479839
NCBI chr 5:141,765,925...141,781,619
Ensembl chr 5:141,766,309...141,781,600
G
Zfand2a
zinc finger AN1-type containing 2A
increases expression
EXP
bromobenzene results in increased expression of ZFAND2A mRNA
CTD
PMID:32479839
NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
G
Zfp136
zinc finger protein 136
increases expression
EXP
bromobenzene results in increased expression of ZFP136 mRNA
CTD
PMID:32479839
NCBI chr18:609,472...618,190
Ensembl chr18:474,716...615,539
G
Zfp354a
zinc finger protein 354A
affects expression
EXP
bromobenzene affects the expression of ZFP354A mRNA
CTD
PMID:32479839
NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
G
Zfp385a
zinc finger protein 385A
decreases expression
EXP
bromobenzene results in decreased expression of ZFP385A mRNA
CTD
PMID:32479839
NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
G
Zfp385b
zinc finger protein 385B
decreases expression
EXP
bromobenzene results in decreased expression of ZFP385B mRNA
CTD
PMID:32479839
NCBI chr 3:62,355,182...62,640,417
Ensembl chr 3:62,355,196...62,640,510
G
Zfp418
zinc finger protein 418
increases expression
EXP
bromobenzene results in increased expression of ZFP418 mRNA
CTD
PMID:32479839
NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242
G
Zfp647
zinc finger protein 647
increases expression
EXP
bromobenzene results in increased expression of ZFP647 mRNA
CTD
PMID:32479839
NCBI chr 7:108,632,248...108,649,264
Ensembl chr 7:108,632,250...108,637,433
G
Zmynd8
zinc finger, MYND-type containing 8
increases expression
EXP
bromobenzene results in increased expression of ZMYND8 mRNA
CTD
PMID:32479839
NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
G
Zscan18
zinc finger and SCAN domain containing 18
increases expression
EXP
bromobenzene results in increased expression of ZSCAN18 mRNA
CTD
PMID:32479839
NCBI chr 1:73,332,883...73,349,846
Ensembl chr 1:73,332,889...73,345,897
G
Esr1
estrogen receptor 1
increases expression
ISO
bromoethane results in increased expression of ESR1 mRNA; bromoethane results in increased expression of ESR1 protein
CTD
PMID:15922381
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases oxidation
ISO
CYP2E1 protein results in increased oxidation of vinyl bromide
CTD
PMID:1664256
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
H2ax
H2A.X variant histone
increases phosphorylation
EXP
vinyl bromide results in increased phosphorylation of H2AX protein
CTD
PMID:37527026
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
G
Mki67
marker of proliferation Ki-67
increases expression
EXP
vinyl bromide results in increased expression of MKI67 protein
CTD
PMID:37527026
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
bromoform binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD
PMID:12505655
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
bromoform binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD
PMID:12505655
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
bromoform binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD
PMID:12505655
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Myc
MYC proto-oncogene, bHLH transcription factor
decreases methylation
ISO
bromoform results in decreased methylation of MYC promoter
CTD
PMID:11099637
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Pcna
proliferating cell nuclear antigen
increases expression
ISO
bromoform results in increased expression of PCNA protein
CTD
PMID:11099637
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
G
Gstt1
glutathione S-transferase theta 1
increases metabolic processing
ISO
GSTT1 protein results in increased metabolism of methyl bromide
CTD
PMID:11305778
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gstt1
glutathione S-transferase theta 1
multiple interactions affects metabolic processing
ISO EXP
GSTT1 protein affects the metabolism of and results in increased activity of methylene bromide GSTT1 protein affects the metabolism of methylene bromide
CTD
PMID:8565128 PMID:11511186 PMID:14727918
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19808
chemical entity
19806
molecular entity
19806
polyatomic entity
19764
heteroatomic molecular entity
19720
halide
18630
organohalogen compound
18502
halohydrocarbon
15686
bromohydrocarbon
1159
1,2,3,4,5,6-hexabromocyclohexane
0
1,2,3-tribromopropane
0
1,2,5,6,9,10-hexabromocyclododecane
0
1,2-dibromoethane
28
1-bromopropane
61
2,6-dibromohydroquinone
0
2,6-dibromophenol +
351
3-bromopropane-1,2-diol
0
bromoalkene +
3
bromoarene +
795
bromoethane
1
bromoform
5
bromomethane
1
dibromomethane
1
Path 2
CHEBI ontology
19808
subatomic particle
19806
composite particle
19806
hadron
19806
baryon
19806
nucleon
19806
atomic nucleus
19806
atom
19806
main group element atom
19756
main group molecular entity
19756
s-block molecular entity
19595
hydrogen molecular entity
19582
hydrides
19095
organic hydride
18669
organic fundamental parent
18669
hydrocarbon
18415
halohydrocarbon
15686
bromohydrocarbon
1159
1,2,3,4,5,6-hexabromocyclohexane
0
1,2,3-tribromopropane
0
1,2,5,6,9,10-hexabromocyclododecane
0
1,2-dibromoethane
28
1-bromopropane
61
2,6-dibromohydroquinone
0
2,6-dibromophenol +
351
3-bromopropane-1,2-diol
0
bromoalkene +
3
bromoarene +
795
bromoethane
1
bromoform
5
bromomethane
1
dibromomethane
1